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After graduating from the University of Coimbra (UC) in 2012 with a Bachelor's Degree in Biology, Sara Escada-Rebelo has enrolled in the Cellular and Molecular Master program (UC). Having always had a passion for the Biology of Reproduction field, during her masters she has developed her thesis on studying potential new biomarkers for the preservation of endangered felines at the Biology of Reproduction and Stem Cell group (Center for Neuroscience and Cell Biology - CNC- Coimbra). She obtained her Master Degree in 2014 with the thesis entitled "A Cat Problem: Characterization of Feline Spermatogonial Stem Cells" that resulted in 2 scientific publications and 2 oral presentations in international conferences. After graduating, Sara kept working in the lab, joined several projects and also had the opportunity to do an internship in human Andrology/Embryology at the Serviço de Medicina da Reprodução (CHUC). In 2016, she was granted and FCT scholarship and enrolled the Biomedicine and Experimental Biology (BEB) PhD program. Ever since, Sara continued to work on the Biology of Reproduction field, now focusing on human male infertility. She has developed her PhD thesis entitled "Mitochondria-targeted molecules to assess and improve human sperm quality: a mitochondrial perspective". To this date Sara has 8 peer-reviewed publications (3 as first author), 3 book chapters (1 as first author) and 4 international conference proceedings. She actively participates in several Science Communication activities, national and international meetings, symposiums and workshops. Sara has also been part of the organizing committee of an international conference (ETW 20 - European Testis Workshop, in 2018) as well as of a PhD student event (BEB Day 2018). Throughout the years, Sara has tutored several undergrad students that came to visit the lab and has lectured in several practical/laboratorial classes.
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Identification

Personal identification

Full name
Sara Escada Rebelo

Citation names

  • Escada-Rebelo, Sara
  • Escada-Rebelo, S.

Author identifiers

Ciência ID
AE18-0048-62E4
ORCID iD
0000-0001-8895-7867

Email addresses

  • sara.rebelo@cnc.uc.pt (Professional)
  • saraescadarebelo@gmail.com (Personal)

Telephones

Telephone
  • 239104422 (Professional)

Addresses

  • Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Rua Larga, Faculdade de Medicina, Pólo I, 1º piso, 3004-517, Coimbra, Coimbra, Portugal (Professional)
  • Center for Innovative Biomedicine and Biotechnology (CIBB), Universidade de Coimbra, 3004-517, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Reproductive Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Clinical Medicine - Andrology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
German Beginner (A1) Intermediate (B1) Intermediate (B1) Elementary (A2) Beginner (A1)
Spanish; Castilian Elementary (A2) Intermediate (B1) Beginner (A1) Elementary (A2) Beginner (A1)
Education
Degree Classification
2016/06 - 2022
Ongoing
 Biologia Experimental e Biomedicina (Doutoramento)
Major in Biologia da Reprodução
Universidade de Coimbra, Portugal
"Targeted molecules to assess and improve human sperm quality: a mitochondrial perspective" (THESIS/DISSERTATION)
2019/05/06 - 2019/05/10
Concluded
 Proteomics Approaches in Life Sciences (Curso de doutoramento (conclusão de unidades curriculares))
Major in Proteomics
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/05/15 - 2017/05/26
Concluded
 Drug Development (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/04/04 - 2017/04/07
Concluded
 Soft Skills for PhD Students in Biomedical Research - Science Communication (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/05/18 - 2016/05/18
Concluded
 OCDE Principles on Good Laboratory Practice (GLP) and Compliance Monitoring – Organization and Studies (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/02/10 - 2016/03/11
Concluded
 Entrepreneurship course: Ineo Start Program (Outros)
Instituto Pedro Nunes, Portugal
2016/03/04 - 2016/03/04
Concluded
 Introduction to the ISO/IEC 17025 of 2005 (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/07 - 2015/10
Concluded
 Estágio em Andrologia/Embriologia Clínica (Outros)
Major in Biologia da Reprodução, Infertilidade
Centro Hospitalar e Universitario de Coimbra EPE Campus dos Hospitais da Universidade de Coimbra, Portugal
2012/09 - 2014/09
Concluded
 Biologia Celular e Molecular (Mestrado integrado)
Major in Biologia da Reprodução
Universidade de Coimbra, Portugal
"A Cat Problem: Characterization of Feline Spermatogonial Stem Cells" (THESIS/DISSERTATION)
 17
2009/09 - 2012/07
Concluded
 Biologia (Licenciatura)
Universidade de Coimbra, Portugal
 14
2010/05 - 2010/07
Concluded
 Estágio de Licenciatura (Outros)
Major in Biologia da Reprodução
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Affiliation

Science

Category
Host institution 		Employer
2015/11/02 - 2016/08/31 Researcher (Research) Laboratoire INNOTECH International, France
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/09/11 - 2015/06/30 Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Projects

Contract

Designation Funders
2018 - Current SR&TD Project: "Searching for novel biomarkers in unknown origin (UOMI) male infertility"
PTDC/MEC-AND/28599/2017
POCI-01-0145-FEDER-028599
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2015/11 - 2016/08 INNOTECH 2015
INNOTECH 2015
Master Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Laboratoire INNOTECH International
2012 - 2015/09/30 "New strategies to recover fertility and genetic variability of endangered felids: development of xenografting and spermatogonial stem cell transplantation in domestic cat as model for endangered felids"
PTDC/CVT/119477/2010
Aluna de Mestrado
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/06/01 - 2015/06/30 "Fertility preservation in endangered felids"
57035966
Aluna de Mestrado
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie, Germany
Associação para a Inovação e Desenvolvimento da FCT

Deutscher Akademischer Austauschdienst
Concluded
Outputs

Publications

Book chapter
  1. Tavares, Renata S.; Escada-Rebelo, Sara; Soares, Maria; Silva, Andreia F; Almeida-Santos, Teresa: AT Santos; Amaral, Sandra; Sousa, Ana Paula; Ramalho-Santos, João. "Mitochondrial Functional Assessment in Mammalian Gametes Using Fluorescent Probes". In Methods in Molecular Biology, edited by Palmeira, Carlos M.; Rolo, Anabela, 57-68. Springer US, 2021.
    Published • 10.1007/978-1-0716-1433-4_5
  2. Escada-Rebelo, Sara; Ramalho-Santos, João. "Oxidative Stress Detection in Human Sperm using Fluorescent Probes". In Methods in Molecular Biology, edited by Carlo Pellicciari; Marco Biggiogera; Manuela Malatesta. Springer Nature, 2021.
    Submitted
  3. Amaral, Sandra; Tavares, Renata S.; Escada-Rebelo, Sara; Silva, Andreia F; Ramalho-Santos, João. "Mammalian Sperm Mitochondrial Function as Affected by Environmental Toxicants, Substances of Abuse, and Other Chemical Compounds". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, edited by Will, Y; Fellow, ATS; Dykens, JA, 185-203. John Wiley & Sons, Inc., 2018.
    Published
Conference abstract
  1. Tavares, Renata S.; Silva, Andreia F; Escada-Rebelo, Sara; Sousa, AP; Almeida-Santos, Teresa: AT Santos; Mas, Y; Jabbour, V; Ramalho-Santos, João. "Spermicidal agents Benzalkonium chloride and Nonoxynol-9: in vitro comparative efficacy and tolerance". Paper presented in 15th Congress of the European Society of Contraception and Reproductive Health (Book of abstracts), Budapest, 2018.
    Published
  2. Escada-Rebelo, Sara; Sousa, AP; Almeida-Santos, Teresa: AT Santos; Paiva, Artur; Ramalho-Santos, João. "On the hunt for quality: Reactive Oxygen Species – can we use them in our favor?". Paper presented in 18th European Testis Workshop (ETW), Óbidos, 2018.
    Published
  3. Escada-Rebelo, Sara; Silva, Andreia F; Amaral, Sandra; Tavares, Renata S.; Baptista, Marta; Ramalho-Santos, João; Mota, Paula C. "Can We Induce Spermatogenesis In Domestic Cat Using An Organ Culture Approach?". Paper presented in 19th European Testis Workshop, Saint-Malo, 2016.
    Published
  4. Escada-Rebelo, Sara; Silva, Andreia F; Ramalho-Santos, João; Mota, Paula C. "New Insights in Spermatogonial Stem Cell Markers". Paper presented in 18th European Testis Workshop (ETW), Elsinore, 2014.
    Published
Conference poster
  1. Escada-Rebelo, Sara; Sousa, Ana P; Almeida-Santos, Teresa; Paiva, Artur; Ramalho-Santos, João. "On the hunt for quality: Reactive Oxygen Species ¿ can we use them in our favor?". Paper presented in Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  2. Escada-Rebelo, Sara; Sousa, Ana P; Almeida-Santos, Teresa: AT Santos; Paiva, Artur; Ramalho-Santos, João (0613-688D-A30E). "Espécies Reativas de Oxigénio: ¿ Poderão ser usadas como indicadores de qualidade espermática?". Paper presented in Sociedade Portuguesa de Medicina da Reprodução (SPMR), 2019.
  3. Escada-Rebelo, Sara; Sousa, Ana P; Almeida-Santos, Teresa; Paiva, Artur; Ramalho-Santos, João. "Reactive Oxygen Species and human sperm quality: Comparisons between distinct fluorescent probes". Paper presented in Society for the Study of Reproduction, 2018.
  4. Escada-Rebelo, Sara; Sousa, Ana P; Almeida-Santos, Teresa; Paiva, Artur; Ramalho-Santos, João. "On the hunt for quality: Reactive Oxygen Species :¿ Can we use them in our favor?". Paper presented in 20th European Testis Workshop, 2018.
  5. Tavares, Renata S.; Silva, Andreia F; Escada-Rebelo, Sara; Sousa, AP; Almeida-Santos, Teresa: AT Santos; Mas, Y; Jabbour, V; Ramalho-Santos, João. "Spermicidal agents Benzalkonium Chloride and Nonoxynol- 9: In vitro comparative efficacy and tolerance". Paper presented in 15th Congress of the European Society of Contraception and Reproductive Health (ESCRH), Budapest, Hungary, 2018.
  6. Escada-Rebelo, Sara; Silva, Andreia F; Amaral, Sandra; Tavares, Renata S.; Baptista, Marta; Ramalho-Santos, João; Mota, Paula C. "Can We Induce Spermatogenesis In Domestic Cat Using An Organ Culture Approach?". Paper presented in 19th European Testis Workshop (ETW), 2016.
  7. Escada-Rebelo, Sara; Silva, Andreia F; Ramalho-Santos, João; Mota, Paula C. "New Insights In Spermatogonial Stem Cell Markers". Paper presented in 18th European Testis Workshop (ETW), 2014.
Journal article
  1. Escada-Rebelo, Sara; Cristo, MI; Amaral, Sandra; Ramalho-Santos, João. "Mitochondrial-targeted Compounds to Assess and Improve Mitochondrial Function in Human Sperm". Antioxidant and Redox Signaling (2022):
    Accepted
  2. Escada-Rebelo, Sara; Mora, FranciscaG; Sousa, AnaP; Almeida-Santos, Teresa: AT Santos; Paiva, Artur; Ramalho-Santos, João. "Fluorescent Probes for the Detection of Reactive Oxygen Species in Human Spermatozoa". Asian Journal of Andrology 22 5 (2020): 465-471. http://dx.doi.org/10.4103/aja.aja_132_19.
    Published • 10.4103/aja.aja_132_19
  3. Tavares, Renata S.; Escada-Rebelo, Sara; Sousa, M.I.; Silva, Andreia F; Ramalho-Santos, João; Amaral, Sandra. "Can Antidiabetic Drugs Improve Male Reproductive (Dys)Function Associated with Diabetes?". Current Medicinal Chemistry 26 22 (2019): 4191-4222. http://dx.doi.org/10.2174/0929867325666181101111404.
    Published • 10.2174/0929867325666181101111404
  4. Silva, Andreia F.; Escada-Rebelo, Sara; Amaral, Sandra; Tavares, Renata S.; Schlatt, Stefan; Ramalho-Santos, João; Mota, Paula C.. "Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?". PLOS ONE 13 2 (2018): e0191912. http://dx.doi.org/10.1371/journal.pone.0191912.
    10.1371/journal.pone.0191912
  5. Tavares, Renata S.; Escada-Rebelo, Sara; Silva, Andreia F; Sousa, M I; Ramalho-Santos, João; Amaral, Sandra. "Antidiabetic therapies and male reproductive function: where do we stand?". Reproduction 155 1 (2018): R13-R37. http://dx.doi.org/10.1530/rep-17-0390.
    Published • 10.1530/rep-17-0390
  6. Escada-Rebelo, S.; Silva, A. F.; Amaral, S.; Tavares, R. S.; Paiva, C.; Schlatt, S.; Ramalho-Santos, J.; Mota, P. C.. "Spermatogonial stem cell organization in felid testis as revealed by Dolichos biflorus lectin". Andrology 4 6 (2016): 1159-1168. http://dx.doi.org/10.1111/andr.12223.
    10.1111/andr.12223
  7. "Mitochondrial functionality and chemical compound action on sperm function.". Current Medicinal Chemistry (2016): http://europepmc.org/abstract/med/27109577.
  8. Tavares, Renata S.; Escada-Rebelo, S.; Correia, M; Mota, Paula C; Ramalho-Santos, João. "The non-genomic effects of endocrine-disrupting chemicals on mammalian sperm". Reproduction 151 1 (2016): R1-R13. http://dx.doi.org/10.1530/rep-15-0355.
    Published • 10.1530/rep-15-0355
Thesis / Dissertation
  1. Rebelo, Sara. "A Cat Problem: Characterization of Feline Spermatogonial Stem Cells". Master, Universidade de Coimbra Centro de Neurociências e Biologia Celular, 2014. http://hdl.handle.net/10316/31333.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/05 On the hunt for quality: Reactive Oxygen Species – can we use them in our favor? 20th European Testis Workshop (ETW)
(Óbidos, Portugal)
2016/06 Can We Induce Spermatogenesis In Domestic Cat Using An Organ Culture Approach? 19th European Testis Workshop (ETW)
(Saint-Malo, France)
2014/05 New Insights in Spermatogonial Stem Cell Markers 18th European Testis Workshop (ETW)
(Elsinore, Denmark)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018/05/23 - 2018/05/27 20th European Testis Workshop (ETW) The ETW is a well-renowned international scientific meeting in the field of Reproduction/Infertility that brings together several experts from different Institutes/Universities all over the world in a very unique, relaxed and "away from any distraction" environment, enhancing the discussion of several up to date topics, boosting collaborations and creating bridges of research excellence between Centers (2018/05/23 - 2018/05/27)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/01/18 - 2018/01/19 BEB Day 2018 Students from the Biomedicine and Experimental Biology (BEB) PhD program promote an annual meeting between current and former students, where they share past experiences, work, advice, among others. This gives the students new perspectives on future careers, particularly on "non-traditional academic careers". During the event, current students are encouraged to submit an abstract of their on-going work. One student will be selected and awarded a prize of 500€, sponsored by Bluepharma, to participate in an international conference (2018/01/18 - 2018/01/19)
Meeting (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/05/16 - 2019/05/16 O gâmeta masculino: o que conseguimos saber só de olhar para ele? Neste workshop irão ser abordados vários assuntos relacionados com o gâmeta masculino, o espermatozoide, com especial foco nas técnicas de análise seminal rotineiramente realizadas num ambiente clínico e de investigação. Serão também abordados alguns projetos presentemente a serem desenvolvidos no grupo de Biologia da Reprodução e Células Estaminais.
Workshop
 Meet.Lab Coimbra
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2014/09 - 2017/09 European Researchers Night (2014, 2015 and 2017), a science communication event where researchers talk about their work to the general non-scientific population
Workshop
 Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/01 - 2019/01 Biology of Reproduction - practical/laboatorial lectures on sperm function analysis to students from the Masters in Biology, Cell and Molecular Biology, and Biochemistry at University of Coimbra Biology of Reproduction (Mestrado) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal