???global.info.a_carregar???
Daniela Patrício holds a Bachelor's degree in Biology and a Master'd degree in Molecular and Cellular Biology both from the Department of Biology, University of Aveiro (Aveiro, Potugal). Her master thesis untitled "Implementation of mammalian two-hybrid system for highthroughput drug screening" was developed in the Institute for Biomedicine under the supervision of Doctor Margarida Fardilha, Doctor Ana Sofia Guimarães and Doctor Vírgilia Silva. She was a Research-fellow in the project "RUNNING away from prostate cancer: WALKING through the molecular basis of physical activity" at Fardilha's Lab. Currently, she is developing her PhD work in the Fardilha's lab under the supervision of Prof. Margarida Fardilha and Prof. João Mano. Her PhD project, entitled "Organoid technology meets male fertility: an innovative strategy to study and modulate sperm function" aims to develop an in vivo 3D epididymal organoid culture able to mimic the epididymis and blood epididymal barrier (BEB) functions to study the role of this organ on sperm physiology and as a tool for pharmacological testing. Daniela is co-investigator of a European Proteomics Infrastructure Consortium (EPIC-XS) funded project and participated as a team member actively engaged in the execution and management of 2 funded projects. In total, she is author of 3 full papers in international peer-review journals with a cumulative impact factor of 21.4, 2 book chapters, received 1 award, and given non-official supervision to several BSc and MSc students. Besides, Daniela collaborated in the organization of scientific meetings and is actively engaged in several science dissemination activities to non-scientific audiences, namely "Techdays", "UA Open Campus", "Futuralia" and "Biologia na Noite".
Read full resume ↓
Identification

Personal identification

Full name
DANIELA MARQUES PATRÍCIO

Citation names

  • Patrício, D

Author identifiers

Ciência ID
B017-5405-058B
ORCID iD
0000-0002-3373-8074
Researcher Id
ABE-6114-2020
Scopus Author Id
58249920600

Email addresses

  • dmpatricio@ua.pt (Professional)

Addresses

  • Universidade de Aveiro - Departamento de Ciências Médicas. Campus Universitário de Santiago - Agra do Crasto , 3810-193 , Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Reproductive Biology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2018/11/01 - 2022
Ongoing
 Biomedicina (Doutoramento)
Universidade de Aveiro, Portugal
2017/09/27
Concluded
 Biologia Molecular e Celular (Mestrado)
Major in Sem especialização
Universidade de Aveiro, Portugal
"Implementation of Mammalian two-hybrid system for highthroughput drugs screnning" (THESIS/DISSERTATION)
 17 (Thesis classification- 18)
2015/07/31
Concluded
 Biologia (Licenciatura)
Universidade de Aveiro, Portugal
"Effects of herbicides in larvae and adults of Zebrafish (Danio rerio)" (THESIS/DISSERTATION)
 14 (Project classification - 19)
Affiliation

Science

Category
Host institution 		Employer
2017/12/01 - 2018/11/30 Researcher (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
2016/06/22 - 2016/09/22 Visiting Researcher (Research) Science Faculty, University of Novi Sad, Serbia

Others

Category
Host institution 		Employer
2018/12/01 - Current PhD Student Universidade de Aveiro, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
(...)
Projects

Grant

Designation Funders
2018/12/01 - Current Organoid technology meets male fertility: an innovative strategy to study and modulate sperm function
SFRH/BD/137487/2018
PhD Student Fellow
Universidade de Aveiro Instituto de Biomedicina, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016/07 - 2019/12 Interacções proteína-proteína como alvos terapêuticos: modulação de complexos da Fosfoproteina Fosfatase 1 na fertilidade masculina
Provided by PTCRIS: PTDC/BBB-BQB/3804/2014
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2019/01/01 - 2019/12/31 Institute for Biomedicine - Aveiro
UID/BIM/04501/2019
Universidade de Aveiro, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/12/01 - 2018/11/30 RUNNING away from prostate cancer: WALKING through the molecular basis of physical activity
PTDC/DTP-DES/6077/2014
Research Fellow
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2017/11/30 Protein-protein interactions as drug targets: modulation of Phosphoprotein Phosphatase 1 complexes in male fertility
PTDC/BBB-BQB/3804/2014
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Other

Designation Funders
2020 - Current Unravelling the PP1 interactome in human dental pulp and its regenerative potential
EPIC-XS-0000085
PhD Student Fellow
European Proteomics Infrastructure Consortium (EPIC-XS)
Ongoing
Outputs

Publications

Book chapter
  1. Freitas, Maria João; Patrício, Daniela; Fardilha, Margarida. "Sperm Signaling Specificity: From Sperm Maturation to Oocyte Recognition". In Tissue-Specific Cell Signaling, edited by Fardilha, Margarida; Silva, Joana V.; Freitas, Maria João, 257-277. Springer International Publishing, 2020.
    10.1007/978-3-030-44436-5_9
  2. Patrício, Daniela; Santiago, Joana; Silva, Joana Vieira. "Testicular Signaling: Team Work in Sperm Production". In Tissue-Specific Cell Signaling, edited by Fardilha, Margarida; Silva, Joana V.; Freitas, Maria João, 225-255. Springer International Publishing, 2020.
    10.1007/978-3-030-44436-5_8
Conference poster
  1. Matos, Bárbara; Patrício, D; Henriques, Magda C.; Freitas, Maria João; Vitorino, Rui; Duarte, Iola F; Oliveira, Paula; et al. "Chronic exercise training attenuates prostate cancer induced molecular remodelling in the testis.". Paper presented in XXI SPB: National Congress of Biochemistry, 2021.
  2. Margarida Fardilha; Mariana Cruz; Jorge Freitas; Patrício, D; Pedro Gomes. "PP1 regenerative potential in tooth decay". Paper presented in 3rd General Meeting of ERNEST COST Action (CA 18133), 2020.
  3. Patrício, D; Mano, JF; Fardilha, Margarida. "Generation of an epididymal organoid: a new path to understand sperm physiology". Paper presented in 7th Advanced Summer School - Interrogations at the Biointerface: “Do organoids fill the in vitro/in vivo gap?”, 2019.
  4. Patrício, D; Fardilha, Margarida. "Epididymal organoid to study and modulate sperm maturation". Paper presented in V Post-Graduate Symposium in Biomedicine, 2019.
  5. Matos, B; Faustino-Rocha, A; Oliveira, P; Patrício, D; Duarte, JA; Henriques, MC; Freitas, MJ; Ferreira, R; Fardilha, M. "Prostate cancer: new insights in prevention of testicular dysfunction by treadmill training". Paper presented in International Conference on cancer and oncology, Amsterdam, 2018.
  6. Matos, B; Oliveira, P; Duarte, JA; Patrício, D; Henriques, MC; Freitas, MJ; Ferreira, R; Fardilha, M. "Treadmill training as a preventive measure for Prostate cancer-induced testicular dysfunction". Paper presented in IV Post-Graduate Symposium in Biomedicine, 2018.
  7. Matos, B.; Oliveira, P; Duarte, JA; Patrício, D; Henriques, MC; Freitas, MJ; Ferreira, R; Fardilha, M. "Prostate cancer: Exercise training in prevention of testicular dysfunction". Paper presented in I NoTeS Congress, 2018.
  8. Matos, B; Oliveira, P; Duarte, JA; Patrício, D; Henriques, MC; Freitas, MJ; Ferreira, R; Fardilha, M. "Unraveling the effect of Exercise training in testis of Prostate cancer subjects". Paper presented in X Biochemistry day, 2018.
  9. Starovlah, IM; Radovic, SM; Patrício, D; Kostic, TS; Andric, SA. "Profile of mitochondrial biogenesis markers and acromosomal reaction are disturbed in spermatozoa from stressed adult rats". Paper presented in CoMBoS - First Congress of Molecular Biologists of Serbia, 2017.
  10. Patrício, D; Freitas, MJ; Guimarães, AS ; Fardilha, M. "Drug screening using Mammalian Two-Hybrid System". Paper presented in III Post-Graduated Symposium on Biomedicine, 2017.
  11. Patrício, D; Freitas, Maria Jo; Guimarães, AS; Fardilha, Margarida. "Targeting protein-protein interaction using mammalian two-hybrid.". Paper presented in Sinal 2017 - 8th Meeting on Signal Transduction, 2017.
Journal article
  1. Anna Kobrock; Bárbara Matos; Daniela Patrício; Liliana Grenho; John Howl; Margarida Fardilha; Pedro S. Gomes. "Enhancing Dental Pulp Stem Cell Proliferation and Odontogenic Differentiation with Protein Phosphatase 1-Disrupting Peptide: An In Vitro Study". Cells (2024): https://doi.org/10.3390/cells13131143.
    10.3390/cells13131143
  2. Elisabete Nascimento-Gonçalves; Fernanda Seixas; Carlos Palmeira; Gabriela Martins; Carolina Fonseca; José Alberto Duarte; Ana I. Faustino-Rocha; et al. "Lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of prostate carcinogenesis". GeroScience (2023): https://doi.org/10.1007%2Fs11357-023-00806-5.
    10.1007/s11357-023-00806-5
  3. Daniela Patrício; Joana Santiago; João F. Mano; Margarida Fardilha. "Organoids of the male reproductive system: Challenges, opportunities, and their potential use in fertility research". WIREs Mechanisms of Disease (2022): https://doi.org/10.1002%2Fwsbm.1590.
    10.1002/wsbm.1590
  4. Joana V. Silva; Joana Santiago; Bárbara Matos; Magda C. Henriques; Daniela Patrício; Ana D. Martins; José A. Duarte; et al. "Effects of Age and Lifelong Moderate-Intensity Exercise Training on Rats’ Testicular Function". International Journal of Molecular Sciences 23 19 (2022): 11619-11619. https://doi.org/10.3390%2Fijms231911619.
    10.3390/ijms231911619
  5. Matos, Bárbara; Patrício, D; Henriques, Magda C.; FREITAS, MARIA JOÃO; Vitorino, Rui; Iola F. Duarte; Howl, John; et al. "Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the testis". Cellular Oncology (2020): http://dx.doi.org/10.1007/s13402-020-00567-9.
    10.1007/s13402-020-00567-9
  6. Patrício, D; Fardilha, Margarida. "The mammalian two-hybrid system as a powerful tool for high-throughput drug screening". Drug Discovery Today (2020): http://dx.doi.org/10.1016/j.drudis.2020.01.022.
    10.1016/j.drudis.2020.01.022
  7. Patricio, Daniela; Fardilha, Margarida. "The mammalian two-hybrid system as a powerful tool for high-throughput drug screening". Drug Discovery Today (2020): https://publons.com/wos-op/publon/35209039/.
    10.1016/J.DRUDIS.2020.01.022
  8. Starovlah, I.; Radovic, S.; Patricio, D.; Kostic, T.; Andric, S.. "Profile of mitochondrial biogenesis markers and acrosomal reaction are disturbed in spermatozoa from stressed adult rats". FEBS Open Bio (2018): https://publons.com/wos-op/publon/35209041/.
  9. Quintaneiro, C.; Patrício, D.; Novais, S.C.; Soares, A.M.V.M.; Monteiro, M.S.. "Endocrine and physiological effects of linuron and S-metolachlor in zebrafish developing embryos". Science of the Total Environment 586 (2017): 390-400. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012285888&partnerID=MN8TOARS.
    10.1016/j.scitotenv.2016.11.153
Thesis / Dissertation
  1. Patrício, D. "Implementation of Mammalian two-hybrid system for highthroughput drugs screnning". Master, Universidade de Aveiro Departamento de Biologia, 2017.
  2. Patrício, D. ""Effects of herbicides in larvae and adults of Zebrafish (Danio rerio)"". Degree, Universidade de Aveiro Departamento de Biologia, 2015.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/06/24 Development of an epididymal organoid: an innovative strategy to study and modulate sperm function Research Summit 2020
University of Aveiro (Aveiro, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/07/26 - 2021/07/27 I Reproductive Science & Fertility Virtual Summit (WebRePRO) (2021/01 - 2021/07)
Conference (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2019/06/27 - 2019/06/27 V Post-graduate Symposium in Biomedicine (2019/07 - 2019/07)
Symposium (Member of the Organising Committee)
 Universidade de Aveiro Instituto de Biomedicina, Portugal
2018/05 - 2018/06/22 Member of the Organizing Committee of I NoTeS Congress - Novel Therapeutic Strategies for Noncommunicable Diseases (2018/06/21 - 2018/06/22)
Congress (Member of the Organising Committee)
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2018/03/23 - 2018/03/25 Organization and participation in UA Open Campus 2018 in Aveiro, Portugal (2018)
Exhibition (Other)
 Universidade de Aveiro, Portugal
2017/10/12 - 2017/10/14 Organization and participation of Techdays: Moduladores da Fertilidade Masculina (2017/10/12 - 2017/10/14)
Exhibition (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2017 - 2017 Vice-President Organizing Committee of the National Biology Student Meeting - 2017 (2017 - 2017)
Congress (Member of the Organising Committee)
2016/10/18 - 2016/10/18 Biologia na Noite 2016 (2016/10/18 - 2016/10/18)
Seminar (Member of the Organising Committee)
 Universidade de Aveiro Departamento de Biologia, Portugal

Núcleo de Estudantes de Biologia - Associação Académica da Universidade de Aveiro, Portugal
2015 - 2015 Biologia na Noite 2015 (2015 - 2015)
Seminar (Member of the Organising Committee)
 Universidade de Aveiro Departamento de Biologia, Portugal

Núcleo de Estudantes de Biologia - Associação Académica da Universidade de Aveiro, Portugal
2014/10/30 - 2014/10/31 VI Jornadas de Cunicultura ASPOC (2014/10/30 - 2014/10/31)
Other (Other)
 Associação Portuguesa de Cunicultura, Portugal

Universidade de Aveiro Departamento de Biologia, Portugal
2014/06/22 - 2014/07/02 7th International Research School (IRS) in Moscow - (2014/06/22 - 2014/07/02)
Other (Other)
 Milset - The International Movement for Leisure Activities in Science and Technology, Belgium
2013/12/06 - 2013/12/08 MicroBiotec'13 - Iberian Congress of Microbiology and Biotechnology 2013 (2013/12/06 - 2013/12/08)
Conference (Other)
 Universidade de Aveiro Departamento de Biologia, Portugal
2013/11 - 2013/11 400 Million Trees Penacova 2013 - Management of volunteers for tree replanting (2013/11 - 2013/11)
Other (Other)
 Floresta Unida, Portugal
2012/10 - 2012/10 400 Million Trees Lousã 2012 - Management of volunteers for tree replanting (2012/10 - 2012/10)
Other (Other)
 Floresta Unida, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/03/22 - 2023/03/24 Functional Supramolecular Polymeric Biomaterials - soft skills training program
Conference
 Functional Supramolecular Polymeric Biomaterials
Universidade de Aveiro CICECO, Portugal
2021/10/06 - 2021/10/07 Jornadas do CICECO21
Meeting
 Jornadas do CICECO21
Universidade de Aveiro CICECO, Portugal
2021/09/29 - 2021/10/01 The genetics of male infertility
Workshop
 The genetics of male infertility
European Society of Human Reproduction and Embryology, Belgium
2021/09/09 - 2021/09/10 Reproductive tissue engineering and fertility preservation
Workshop
 Reproductive tissue engineering and fertility preservation
European Society of Human Reproduction and Embryology, Belgium
2020/11/23 - 2020/11/23 Organoids With]Out[ Borders
Symposium
 Organoids With]Out[ Borders
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/07/05 - 2020/07/08 ESHRE virtual 36th Annual Meeting
Meeting
 ESRHE Annual Meeting 2020
European Society of Human Reproduction and Embryology, Belgium
2019/10/11 - 2019/10/11 Fostering Responsible Conduct of Research
Seminar
 Fostering Responsible Conduct of Research
Universidade de Aveiro Escola Superior Aveiro Norte, Portugal
2019/09/24 - 2019/09/26 6th International workshop: Molecular Andrology 2019
Workshop
 Molecular Andrology 2019
Justus-Liebig-University of Giessen, Germany
2019/09/23 - 2019/09/24 12th meeting of the Network for Young Researchers in Andrology (NYRA)
Meeting
 12th NYRA meeting
Justus Liebig Universitat Giessen, Germany
2019/09/11 - 2019/09/13 1st European Training Schoolof the European Network Riseup-PPD Systematic Reviews and Meta-Analysis
Workshop
 1st European Training Schoolof the European Network Riseup-PPD
European Cooperation in Science and Technology, Belgium

Universidade de Coimbra Faculdade de Psicologia e de Ciências da Educação, Portugal
2019/07/03 - 2019/07/05 Research summit 2019
Symposium
 Research summit 2019
Universidade de Aveiro, Portugal
2019/06/27 - 2019/06/28 7th Advanced Summer School - "Interrogations at the Biointerface: Do organoids fill the in vitro/in vivo gap?”
Conference
 7th Advanced Summer School - "Interrogations at the Biointerface: Do organoids fill the in vitro/in vivo gap?”
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/06/14 - 2019/06/14 “Como comunicar ciência”
Workshop
 “Como comunicar ciência”
Universidade de Aveiro, Portugal
2019/04/04 - 2019/04/04 Futurália 2019 (Lisboa, Portugal) representing the Department of Medical Sciences, University of Aveiro and Foundation for Science and Technology
Exhibition
 Futurália 2019
Fundação para a Ciência e a Tecnologia, Portugal
2019 - 2019/02/22 “Scientific Writing” during the PhD preparation
Seminar
 “Scientific Writing” during the PhD preparation
2018/11/28 - 2018/11/29 Research Summit 2018
Symposium
 Research Summit 2018
Universidade de Aveiro, Portugal
2018/11/14 - 2018/11/14 Conferência "Humanos do Futuro", integrada no Ciclo de Conferências "Mês da Educação e da Ciência 2018" organizado pela Fundação Francisco Manuel dos Santos
Conference
 Humano do Futuro
Universidade de Aveiro, Portugal
2018/09/20 - 2018/09/20 Organoids and other advanced tissue models for biomedical research
Meeting
 Organoids and other advanced tissue models for biomedical research
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/07/05 - 2018/07/05 IV Post-graduate Symposium in Biomedicine
Symposium
 IV Postgrad Symposium in Biomedicine
Universidade de Aveiro Instituto de Biomedicina, Portugal
2018/03/07 - 2018/03/07 Application of bioinformatics tools to data analysis in Systems Medicine
Workshop
 Application of bioinformatics tools to data analysis in Systems Medicine
Universidade de Aveiro Instituto de Biomedicina, Portugal
2018/01/08 - 2018/01/12 Advanced Course in Cancer Biology
Other
 International Intensive Course of Cancer Biology - Advances in epidemiology, etiology & therapy
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2017/06/07 III Post-graduate Symposium in Biomedicine
Symposium
 III Post-graduate Symposium in Biomedicine
Universidade de Aveiro Instituto de Biomedicina, Portugal
2017/06/01 - 2017/06/02 8th Meeting on Signal transduction- SINAL 2017
Meeting
 8th Meeting on Signal transduction- SINAL 2017
Instituto de Medicina Molecular, Portugal
2017 - 2017/04/27 To move or not to move: How to control sperm motility?
Meeting
 To move or not to move: How to control sperm motility?
Universidade de Aveiro Instituto de Biomedicina, Portugal
2015/05 - 2015/05 3rd Workshop of Immunology
Workshop
 3rd Workshop of Immunology
Universidade de Aveiro Departamento de Química, Portugal

Association member

Society Organization name Role
2020/05 - Current Network for Young Researchers in Andrology - International Network for Young Researchers in Male Fertility
2019/02/01 - Current European Society of Human Reproduction and Embryology Student membership (E-19-00254)
2017/03 - 2018/03 Ordem dos Biólogos
2016/01 - 2016/12 Núcleo de Estudantes de Biologia - Associação Académica da Universidade de Aveiro Member responsible of communication and image department
2015/01 - 2015/12 Núcleo de Estudantes de Biologia - Associação Académica da Universidade de Aveiro Member responsible for administrative department

Committee member

Activity description
Role 		Institution / Organization
2017 - 2017 Vice-President Organizing Committee of the National Biology Student Meeting - 2017
President / Vice-president

Mentoring / Tutoring

Topic Student name
2019/09/15 - 2020/02/19 Characterization of the phosphoprotein phosphatase 1 interactome in human dental pulp and its regenerative potential Jorge Freitas
2018/11/15 - 2019/06 Cell Culture Joana Tulha
2018/06 - 2018/08 Molecular biology techniques - Gonçalo Outeiro
Distinctions

Award

2019 Full grant to participate in the 1st European Training School of the European Network Riseup-PPD
European Cooperation in Science and Technology, Belgium

Other distinction

2021 Image selected for cover of scientific journal "Cellular Oncology" April - volume 44
Springer Nature Switzerland AG, Switzerland
2018 PhD Grant SFRH/BD/137487/2018
Fundação para a Ciência e a Tecnologia, Portugal
2016 Erasmus Internship Grant
University of Novi Sad, Serbia

Universidade de Aveiro, Portugal
2014 Erasmus Internship Grant
Universidade de Aveiro, Portugal