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Nádia E. Santos received her Biochemistry degree from the University of Aveiro (UA) in 2016 and masters in biotechnology from the same institution in 2017, having, since then, devoted her professional life to Medicinal Chemistry. During her bachelors degree, she developed research on ruthenium complexes with 3,5-disubstitited pyrazoles for cytotoxic activity. The topic was further developed in her masters thesis, during which she identified a few complexes with activity against stomach cancer cell lines. The masters helped Nadia improve her skills in both organic and inorganic chemistry and in characterisation methods such as NMR, MS and FTIR. She further pursued her keen interest in drug development during a one-year research internship in the medicinal chemistry department of Bial where she learned how to search and design new compounds, interpret NMR results, and discuss structure-activity relationship. She prepared a library of proprietary drug candidates that for subsequent testing at Bial's biology department. Working in a team with various international members, she strengthened her command in English. Language skills were regularly use in the monthly meetings of the Medicinal Chemistry group, which had English as official language. Presently, Nádia is back to academic research, working with the Bioplus project: Development of diamond-optic fibre biosensors for detection of IgE. Merging optoelectronics with organic and analytical chemistry, this interdisciplinary project has constantly pushed her to develop and deepen her skills and to learn new concepts and techniques (SEM, powder X-Ray diffraction, Raman, XPS). Outcomes of the first six months with Bioplus include one poster presentation on surface functionalisation of diamond by photochemical grafting, recently presented in the 13th Inorganic & Bioinorganic Chemistry Conference of SPQ, and a background review paper on diamond sensors for biomolecules in the journal "Applied Sciences". Production: Nádia authored four SCI-indexed papers, one bookchapter, and presented three posters in national/international conferences. Science dissemination: Nádia authored one science dissemination paper (in "Boletim da Sociedade Portuguesa da Química"). She participated in a science communication contest called "Famelab", having qualified as a semifinalist (top10). She gave an interview on her participation at Famelab in 2017 at the radio show "Click" in Antena 1 RTP. In 2018, she was a science communication coach at the soft skills workshop cycle organized by UA¿s "Núcleo de Estudantes de Química ".
Identification

Personal identification

Full name
Nádia Alexandra Esteves Santos

Citation names

  • Santos, Nádia
  • Nádia E. Santos

Author identifiers

Ciência ID
B119-FAE8-F47B
ORCID iD
0000-0003-4560-6172

Telephones

Mobile phone
  • 914106170 (Personal)

Addresses

  • Rua 62, número 156, Apartamento 103, , 4500-363, Espinho, Espinho, Portugal (Personal)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences - Inorganic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2022/10 - 2026/10/21
Ongoing
Química (Doutoramento)
Major in Química inorgânica
Universidade de Aveiro, Portugal
2016/03/29 - 2017/07/27
Concluded
Biotecnologia (Mestrado)
Major in Molecular
Universidade de Aveiro, Portugal
"Synthesis and evaluation of new pyrazoles, glycosylpyrazoles and rutheniumpyrazoles for antioxidant and antitumoral activity " (THESIS/DISSERTATION)
16 (out of 20)
2011/09/20 - 2016/01/19
Concluded
Bioquímica (Licenciatura)
Universidade de Aveiro, Portugal
12 (out of 20)
Affiliation

Science

Category
Host institution
Employer
2021/10/01 - 2022/01/31 Researcher (Research) Instituto de Telecomunicações Campus Universitário de Santiago, Portugal
Universidade de Aveiro, Portugal
2019/01/01 - 2019/12/31 Research Trainee (Research) Laboratórios Bial, Portugal

Others

Category
Host institution
Employer
2018/05/01 - 2018/12/28 Analista químico Grupo Tecnimede, Portugal
Outputs

Publications

Book chapter
  1. Santos, Nádia E.; Braga, Susana S.; Almeida Paz, Filipe A.. "Ruthenophenanthroline complexes active against tripanosomids". In A closer look at phenanthroline, edited by Amies, William. Hauppage, NY, United States: Novascience, 2020.
    Published
Conference poster
  1. Santos, Nádia; Braga, Susana S.; Figueira, Flávio; A. Almeida Paz, Filipe. Corresponding author: Santos, Nádia. "A new cerium-based metal-organic framework with azobenzene-4,4’-dicarboxylic acid as ligand". Paper presented in XXVII Encontro Nacional da SPQ, 2023.
  2. MENDES, JOANA C.; Braga, Susana S.; Deuermeier, Jonas; Guieu, Samuel; Figueira, Flávio; Filipe A. Paz; Neto, Miguel Ângelo da Costa. "Functionalisation of HFCVD diamond for the recognition of biomolecules". Paper presented in Biophysics Festival 2022, 2022.
  3. Santos, Nádia; Figueira, Flávio; Neto, Miguel Ângelo da Costa; Guieu, Samuel; Deuermeier, Jonas; Paz, Filipe A. Almeida; MENDES, JOANA C.; Braga, Susana S.. Corresponding author: Santos, Nádia. "Functionalisation of HFCVD diamond for the regognition of biomolecules". Paper presented in 2nd Biophysics Festival (Encontro de Jovens Biofísicos), 2022.
  4. Nádia E. Santos; Braga, Susana S.; Joana C. Mendes; Miguel Neto; Flávio Figueira; Filipe A. Paz; Deuermeier, Jonas; Leandro Felício. Corresponding author: Nádia E. Santos. "Functionalisation of HFCVD diamond with (3-aminopropyl)triethoxysilane and fluorescein isothiocyanate (FITC)". Paper presented in 13 th Inorganic & Bioinorganic Chemistry Conference, 2022.
  5. Nádia E. Santos; Leandro Felício; Susana Santos Braga; Joana C. Mendes; Flávio Figueira; Miguel Neto; Jonas Deuermeir. "Functionalization of HFCV diamond with (3-aminopropyl)triethoxysilane and fluorescein isothiocyanate (FITC)". Paper presented in XIII Inorganic and Bioinorganic Chemistry, 2022.
  6. Santos, Nádia E. (B119-FAE8-F47B); Braga, Susana S.; Cardoso, Susana M.; Silva, Vera L. M.. "Probing the medicinal properties of 3(5)-(2-hydroxyphenyl)-5(3)styryl-1H-pyrazoles and their ruthenium complexes". Paper presented in 13º Encontro Nac. Química Orgânica – 6º Encontro Nac. Química Medicinal (13ENQO-6ENQT), 2020.
  7. Nádia E. Santos; Cardoso, Susana M.; Silva, Vera L. M.; Braga, Susana S.. "Quercetin encapsulation into beta and gamma cyclodextrins and its effects on the antioxidant activity". Paper presented in Iberphenol, 2020.
Journal article
  1. Nádia E. Santos; Flávio Figueira; Miguel Neto; Filipe A. Almeida Paz; Susana Santos Braga; Joana C. Mendes. "Diamonds for Life: Developments in Sensors for Biomolecules". Applied Sciences (2022): https://doi.org/10.3390/app12063000.
    10.3390/app12063000
  2. Susana Santos Braga; Jéssica S. Barbosa; Nádia E. Santos; Firas El-Saleh; Filipe A. Almeida Paz. "Correction: Braga et al. Cyclodextrins in Antiviral Therapeutics and Vaccines. Pharmaceutics 2021, 13, 409". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14030499.
    10.3390/pharmaceutics14030499
  3. Nádia Santos; Susana Braga. "Redesigning Nature: Ruthenium Flavonoid Complexes with Antitumour, Antimicrobial and Cardioprotective Activities". Molecules (2021): https://doi.org/10.3390/molecules26154544.
    10.3390/molecules26154544
  4. Nádia E. Santos; Braga, Susana S.; Almeida Paz, Filipe A. (FC11-CD20-CC3E). "Terapêutica farmacológica da Leishmaniose: perspetiva atual e desenvolvimento de complexos de ruténio leishmanicidas". Boletim da Sociedade Portuguesa da Química (2020): https://www.spq.pt/files/files/BSPQ/15.pdf.
    Published
  5. Santos, Nádia E.; Carreira, Ana R.F.; Silva, Vera L. M.; Braga, Susana Santos. "Natural and Biomimetic Antitumor Pyrazoles, A Perspective". Molecules 25 6 (2020): 1364. http://dx.doi.org/10.3390/molecules25061364.
    Published • 10.3390/molecules25061364
Activities

Event participation

Activity description
Type of event
Event name
Institution / Organization
2018/03/12 - 2018/03/12 Coach on science communication at the soft skills workshop cycle, organized by "Núcleo de Estudantes de Química da Universidade de Aveiro".
Workshop
1ª Semana de Workshops de Soft Skills
Universidade de Aveiro Departamento de Química, Portugal

Interview (tv / radio show)

Program Topic
2017/05/27 - 2017/05/27 Interviewed at the radio show "Click" in Antena 1 - RTP Famelab: projetos finalistas de 2 cientistas da Universidade de Aveiro e a investigação de Cátia Santos e Nádia Santos
Distinctions

Award

2017 (Top10) Finalist at Famelab
Instituto Gulbenkian de Ciência, Portugal

British Council Portugal, Portugal