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In 2023 I finished the Health Sciences Master’s degree program from the Health and Life Sciences Research Institute (ICVS), from the University of Minho, in Braga, with a final grade of 19/20. In the second year I started my thesis project named “Characterization and biological impact of medulloblastoma immune profile”, under the supervision of Dr. Rui Manuel Reis in partnership with his team from the Cancer Hospital of Barretos in Brazil and the Tumor and Microenvironment Interactions team from the Institute for Research and Innovation in Health, in Porto. I’ve concluded the project with a grade of 20/20. For this I developed microarray and RNA sequencing analysis skills with the R software through online courses, help from colleagues and other available sources. Additionally improved my cell culture skills and developed and characterized 3D spheroid models using cell lines. This project enabled 4 poster and 2 oral presentations in congresses and symposiums. Importantly, it resulted in my first published scientific article. In 2023 our team was awarded a grant for the project "Role of CD24, an immune checkpoint, in the biology and therapy of medulloblastoma". After the master's became a research fellow at ICVS under that same project. Accepted for the FCT Doctoral Fellowship 2024 with the project "Unravelling the role of CCL18 in promoting colorectal cancer aggressiveness".
Identification

Personal identification

Full name
Rui Marques

Citation names

  • Marques, Rui F.

Author identifiers

Ciência ID
B419-4576-86F9

Telephones

Mobile phone
  • (+351) 934691584 (Personal)

Addresses

  • Rua do Pinheiral, n36, 4esq, 4805-640, Sande São Clemente, Guimarães, Portugal (Personal)

Knowledge fields

  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2021/09/06 - 2023/11/30
Concluded
Mestrado em Ciências da Saúde (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"Characterization and biological impact of medulloblastoma immune profile " (THESIS/DISSERTATION)
19
2023 - 2023
Concluded
Cell functional and phenotypical analysis: the usefulness of flow cytometry and related tools (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
17
2022 - 2022
Concluded
Laboratory Animal Science (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
16
2018/09/27 - 2021/06/27
Concluded
Ciências Biomédicas (Licenciatura)
Major in Molecular
Universidade de Aveiro, Portugal
16
Affiliation

Science

Category
Host institution
Employer
2023/11/02 - 2024/06/30 Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Projects

Grant

Designation Funders
2023/11/02 - 2024/06/30 Role of CD24, an immune checkpoint, in the biology and therapy of medulloblastoma
Research Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Hospital de Câncer de Barretos Instituto de Ensino e Pesquisa, Brazil

Hospital de Câncer de Barretos, Brazil
Fundação Rui Osório de Castro (FROC)
Ongoing
Outputs

Publications

Conference poster
  1. Marques, Rui F.. "Characterization of the immune microenvironment of medulloblastoma’s molecular subgroups". Paper presented in ASPIC-ASEICA International Meeting 2023 - Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  2. Marques, Rui F.. "Characterization and biological impact of medulloblastoma's immune profile". Paper presented in Innovate Competition 14.0, iMED Conference, 2022.
  3. Marques, Rui F.. "Identification and validation of CD276, PVR, CD47 and CD24 as ideal targets forimmunotherapy in medulloblastoma". Paper presented in 4th National Encounter for Young Researchers in Oncology, 2022.
  4. Marques, Rui F.. "Digital expression profile of immune checkpoint genes across medulloblastoma subgroups". Paper presented in Portuguese Association of Cancer Research 5th International Congress, 2022.
Journal article
  1. Zucca, Luis Eduardo Rosa; Laus, Ana Carolina; Sorroche, Bruna Pereira; Paro, Eduarda; Sussuchi, Luciane; Marques, Rui Ferreira; Teixeira, Gustavo Ramos; et al. "Immune-checkpoint gene expression and BCG response in non-muscle invasive bladder cancer". Translational Oncology 46 (2024): 102003. http://dx.doi.org/10.1016/j.tranon.2024.102003.
    10.1016/j.tranon.2024.102003
  2. Marques, Rui F.. "Digital expression profile of immune checkpoint genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets". Frontiers in Immunology 14 (2023): 1664-3224. https://www.frontiersin.org/articles/10.3389/fimmu.2023.1062856.
    Open access • Published
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/03/12 Deciphering the Immune Signature of Medulloblastoma Subgroups: Implications for Immunotherapy Paedriatic Cancer Symposium
Champalimaud Centre for the Unknown (Lisbon, Portugal)
2023/02/03 Identification of CD24 and CD276 as promising targets for immune checkpoint blockade in medulloblastoma XIII National Congress
Portuguese Association of Neuro-oncology (Porto, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2024 - 2024 2024 World Cancer Day Event - Cancro em Perspetiva (2024 - 2024)
Round table (Member of the Organising Committee)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2018 Staff member of the “X National Journeys of Biomedical Sciences.” (2018 - 2018)
Congress (Member of the Organising Committee)
Universidade de Aveiro, Portugal
Distinctions

Award

2023 Research Grant
Fundação Rui Osório de Castro (FROC), Portugal