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Ana Sofia Martins Serras completed the Integrated Master Degree in Pharmaceutical Sciences in 2014/12/04 by Instituto Superior de Ciências da Saúde Egas Moniz and is currently an effective member of the Ordem dos Farmacêuticos and student member of Sociedade Portuguesa de Farmacologia (SPF) and Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC). Is presently PhD student at the Research Institute for Medicines from the University of Lisbon (iMed.ULisboa). Has previously been the technical director of VF 1883 Pharmaceuticals and the responsible pharmacist in two pharmacies. Has authored 4 journal articles (3 as first author) and 2 book chapters, 9 conference abstract, 12 oral communications and 18 poster communications. Organized 1 event and participated in 2 scientific expeditions, namely a Summer School in Estonia and a Short-term Scientific Mission in Spain. Supervised 5 students and professionals at the pharmacy and was the tutor of 2 other students at the Faculty of Pharmacy. Works in Medical and Health Sciences with emphasis on Basic Medicine, namely Pharmacology and Toxicology. In her curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Human umbilical cord mesenchymal stem cells; Exosomes; Secretome; Hepatocyte-like cells; Hepatic differentiation; In vitro toxicology; In vitro alternative models; Hepatotoxicity; Liver regeneration; Pharmacy; Medicine; Leadership; Public advice; Pharmaceutical Sciences.
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Identification

Personal identification

Full name
Ana Sofia Martins Serras

Citation names

  • Serras, Ana Sofia
  • Serras, Ana S.

Author identifiers

Ciência ID
B41D-2E23-CD07
ORCID iD
0000-0002-7941-9511

Email addresses

  • ana.serras@edu.ulisboa.pt (Professional)
  • ana.sm.serras@gmail.com (Personal)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Toxicology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Upper intermediate (B2) Advanced (C1)
Education
Degree Classification
2021/03/05 - 2025
Ongoing
 Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02/18 - 2019/06/28
Attended
 Biopharmaceutical Sciences - 3 curricular units (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/07/09 - 2017/07/01
Concluded
 Homeopathic Medicines (Module I and II) (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
 18 / 17
2017/03/07 - 2017/06/01
Concluded
 Pharmaceutical Marketing (Pós-Graduação)
Ordem dos Farmaceuticos, Portugal

Centro de formação CaF, Portugal
17
2009/09/15 - 2014/12/04
Concluded
 Pharmaceutical Sciences (Mestrado integrado)
Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
"Células estromais mesenquimais (MSC) como agentes terapêuticos" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2019/06/03 - 2021/03/04 Research Trainee (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Other Careers

Category
Host institution 		Employer
2020/06 - 2021/10 Assessor Superior (Técnico Superior de Saúde - Farmácia) VF 1883 Pharmaceuticals, Lda., Portugal
2020/08 - 2021/02 Assistente Principal (Técnico Superior de Saúde) Farmodisseia, Lda., Portugal
2017/05/01 - 2020/07 Assessor (Técnico Superior de Saúde - Farmácia) Laziapho, Lda., Portugal
Chemist Store - Farmácia Silva Carvalho, Portugal
2016/03/01 - 2017/04/30 Assessor (Técnico Superior de Saúde - Farmácia) Laziapho, Lda., Portugal
Farmácia Alvalade, Portugal
2015/03/01 - 2016/02/29 Assistente Principal (Técnico Superior de Saúde - Farmácia) Farmodisseia, Lda., Portugal
Farmácia Sanex, Portugal
2014/12/01 - 2015/02/28 Assistente Principal (Técnico Superior de Saúde - Farmácia) Farmodisseia, Lda., Portugal
Farmácia Fernandes Borges, Portugal
2014/05 - 2014/07 Estagiário (3º e 4º Ano) (Técnico Superior de Saúde - Farmácia) Farmácia Duque D' Ávila, Portugal
Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
2014/03 - 2014/04 Estagiário (3º e 4º Ano) (Técnico Superior de Saúde - Farmácia) Hospital Garcia de Orta EPE, Portugal
Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
2013/08/05 - 2013/08/21 Estagiário (3º e 4º Ano) (Técnico Superior de Saúde - Farmácia) CEFARM Bialystok S.A. Apteka, Poland
International Pharmaceutical Student's Federation, Netherlands
Projects

Grant

Designation Funders
2020/01/06 - Current Understanding the underlying mechanisms by which mesenchymal stem cells promote liver regeneration: the specific role of exosomes (EXO-THER)
PTDC/MEDTOX/ 29183/2017
2021.04902.BD
PhD Student Fellow
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Miranda, Joana P; Rodrigues, JS; Serras, Ana S.; Camões, SP. "Metodologias avançadas para a avaliação da toxicidade alimentar". In Toxicologia Alimentar. Pactor-LIDEL–Edições Técnica, Lda, 2023.
    Accepted
  2. Serras, Ana S. (B41D-2E23-CD07); Cipriano, Madalena; Silva, Pedro; Miranda, Joana P. (001A-6278-C231). "Challenges for Deriving Hepatocyte-Like Cells from Umbilical Cord Mesenchymal Stem Cells for In Vitro Toxicology Applications". In Novel Perspectives of Stem Cell Manufacturing and Therapies, edited by Maurício, Ana Collette. United Kingdom: IntechOpen, 2020.
    Published
Conference abstract
  1. Segovia-Zafra, Antonio; Villanueva, Marina; Serras, Ana Sofia; Matilla, Gonzalo; Bodoque-García, Ana; Di Zeo-Sánchez, Daniel E.; Niu, Hao; et al. "Control compounds used to validate in vitro models of idiosyncratic drug-induced liver injury: a systematic review". Paper presented in 5th Meeting of Translational Hepatology, Seville, 2023.
    10.1016/s0168-8278(23)00648-7
  2. Serras, A.S.; Camões, S.P.; Rodrigues, J.S.; Vej-Nielsen, J.M.; Vitorino, R.; Miranda, J.P.. "Exosomes derived from mesenchymal stem cells exposed to hepatic injury signals reveal a distinct protein signature associated to pro-regenerative effects". Paper presented in EUROTOX 2023 - 57th Congress of the European Societies of Toxicology, Ljubljana, 2023.
    10.1016/s0378-4274(23)00966-9
  3. Segovia-Zafra, A.; Villanueva-Paz, M.; Serras, A.S.; Matilla-Cabello, G.; Bodoque, A.; Di Zeo-Sánchez, D.E.; Niu, H.; et al. "A systematic review of control compounds tested for validation of Drug-Induced Liver Injury (DILI) in vitro models". Paper presented in EUROTOX 2023 – 57th Congress of the European Societies of Toxicology, Ljubljana, 2023.
    10.1016/s0378-4274(23)00727-0
  4. Trigo, C.M.; Camões, S.P.; Serras, Ana S.; Gava, M.; Vitorino, R.; Vaz, A.R.; Brites, D.; Solá, S.; Miranda, J.P.. "Preconditioning MSCs with IFN-y as a promising therapeutic strategy towards COVID-19-induced neurological damage". Paper presented in EUROTOX 2023 - 57th Congress of the European Societies of Toxicology, Ljubljana, 2023.
    10.1016/s0378-4274(23)00823-8
  5. Saraiva Rodrigues, J.; Faria-Pereira, A.; Camões, S.P.; Serras, Ana S.; Morais, V.A.; Ruas, J.L.; Miranda, J.P.. "The role of glucose homeostasis and glucocorticoid signalling for the development of relevant hepatic in vitro models for toxicology, drug metabolism and energy metabolism studies". Paper presented in EUROTOX 2023 - 57th Congress of the European Societies of Toxicology, Ljubljana, 2023.
    10.1016/s0378-4274(23)00710-5
  6. Camões, S.P.; Simões, I.T.; Trigo, C.M.; Serras, Ana S.; Miranda, J.P.. "Pro-inflammatory INF-y and TNF-a stimuli induce MSC-derived exosomes immunosuppressive and tissue regenerative effects". Paper presented in EUROTOX 2023 - 57th Congress of the European Societies of Toxicology, Ljubljana, 2023.
    10.1016/s0378-4274(23)00548-9
  7. Serras, Ana S.; Camões, S.P.; Rodrigues, J.S.; Miranda, J.P.. "Exosomes derived from primed Mesenchymal Stem Cells improve cell viability on an APAP-induced hepatic injury in vitro model". Paper presented in ICT 2022 - XVIth International Congress of Toxicology, Maastricht, 2022.
    10.1016/j.toxlet.2022.07.476
  8. Serras, Ana S. (B41D-2E23-CD07); Ribero, Daniela; Camões, Sérgio P.; Rodrigues, Joana S. (531C-FA09-7DBD); Miranda, Joana P. (001A-6278-C231). "The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Drug-induced Hepatic Injury". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Braga, 2022.
  9. Rodrigues, Joana S. (531C-FA09-7DBD); Gonçalves, Madalena T.; Serras, Ana S.; Camões, Sérgio P.; Miranda, Joana P. (001A-6278-C231). "Glucagon Induces a More Periportal Phenotype in Hepatocyte-Like Cells". Paper presented in 51ª Reunião Sociedade Portuguesa de Farmacologia (SPF)/39ª Reunião Farmacologia Clínica/20ª Reunião Toxicologia, Lisbon (online), 2021.
  10. Serras, Ana S. (B41D-2E23-CD07); Antunes, Bernardo; Camões, Sérgio P.; Dionísio, Flávio; Costa, Vera M.; Yazar, Volkan; Remião, Fernando; et al. "The Secretome of Mesenchymal Stem Cells Modulates Doxorubicin-induced Cytotoxicity". Paper presented in 51ª Reunião Sociedade Portuguesa de Farmacologia (SPF)/39ª Reunião Farmacologia Clínica/20ª Reunião Toxicologia, Lisbon (online), 2021.
  11. Serras, Ana S. (B41D-2E23-CD07); Rodrigues, Armanda; Rodrigues, Joana S. (531C-FA09-7DBD); Miranda, Joana P. (001A-6278-C231). "Hepatocyte-like Cells as a Model for Hepatotoxicity Studies". Paper presented in 50ª Reunião Sociedade Portuguesa de Farmacologia (SPF)/38ª Reunião Farmacologia Clínica/19ª Reunião Toxicologia, Coimbra, 2020.
  12. Camões, Sérgio P.; Dias, Catarina T.; Rodrigues, Joana S. (531C-FA09-7DBD); Serras, Ana S. (B41D-2E23-CD07); Gaspar, Maria M.; Simões, Sandra; Ferreira, Rita; et al. "Delivery of exosomes derived from 3D-cultured human neonatal mesenchymal stromal cells improves cutaneous wound healing". Paper presented in 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Lisbon, 2019.
    10.3389/978-2-88945-675-8
Conference poster
  1. Serras, Ana S.; Camões SP; Rodrigues JS; Vej-Nielsen JM; Vitorino R; Miranda JP. "Hepatic SOS signals preconditioning modulate MSC secretome and derived exosomes towards a more pro-regenerative profile". Paper presented in ETRS & SPCE-TC Joint Meeting 2023, 2023.
  2. Segovia-Zafra, Antonio; Villanueva, Marina; Serras, Ana S.; Matilla, Gonzalo; Bodoque-García, Ana; Di Zeo-Sánchez, Daniel E.; Niu, Hao; et al. "Control compounds used to validate in vitro models of idiosyncratic drug-induced liver injury: a systematic review". Paper presented in 5th Meeting of Translational Hepatology, 2023.
    10.1016/s0168-8278(23)00648-7
  3. Camões SP; Simões IT; Trigo CT; Serras, Ana S.; Miranda JP. "IFN-y and TNF-a preconditioning enhances the MSCs immunosuppressive and tissue regenerative abilities". Paper presented in ETRS & SPCE-TC Joint Meeting 2023, 2023.
  4. Trigo CT; Camões SP; Branco S; Serras, Ana S.; Matos AT; Gava M; Vitorino R; et al. "Preconditioning mesenchymal stem cells with IFN-y enhances their neuroregeneration and immunomodulatory properties". Paper presented in ETRS & SPCE-TC Joint Meeting 2023, 2023.
  5. Serras, Ana S.; Camões, S.P.; Rodrigues, J.S.; Vej-Nielsen, J.M.; Vitorino, R.; Miranda, J.P.. "Exosomes derived from mesenchymal stem cells exposed to hepatic injury signals reveal a distinct protein signature associated to pro-regenerative effects". Paper presented in EUROTOX 2023 – 57th Congress of the European Societies of Toxicology, 2023.
    10.1016/s0378-4274(23)00966-9
  6. Segovia-Zafra, A.; Villanueva-Paz, M.; Serras, Ana S.; Matilla-Cabello, G.; Bodoque, A.; Di Zeo-Sánchez, D.E.; Niu, H.; et al. "A systematic review of control compounds tested for validation of Drug-Induced Liver Injury (DILI) in vitro models". Paper presented in EUROTOX 2023 – 57th Congress of the European Societies of Toxicology, 2023.
    10.1016/s0378-4274(23)00727-0
  7. Trigo, C.M.; Camões, S.P.; Serras, Ana S.; Gava, M.; Vitorino, R.; Vaz, A.R.; Brites, D.; Solá, S.; Miranda, J.P.. "Preconditioning MSCs with IFN-y as a promising therapeutic strategy towards COVID-19-induced neurological damage". Paper presented in EUROTOX 2023 - 57th Congress of the European Societies of Toxicology, 2023.
    10.1016/s0378-4274(23)00823-8
  8. Saraiva Rodrigues, J.; Faria-Pereira, A.; Camões, S.P.; Serras, Ana S.; Morais, V.A.; Ruas, J.L.; Miranda, J.P.. "The role of glucose homeostasis and glucocorticoid signalling for the development of relevant hepatic in vitro models for toxicology, drug metabolism and energy metabolism studies". Paper presented in EUROTOX 2023 – 57th Congress of the European Societies of Toxicology, 2023.
    10.1016/s0378-4274(23)00710-5
  9. Camões, S.P.; Simões, I.T.; Trigo, C.M.; Serras, Ana S.; Miranda, J.P.. "Pro-inflammatory INF-y and TNF-a stimuli induce MSC-derived exosomes immunosuppressive and tissue regenerative effects". Paper presented in EUROTOX 2023 - 57th Congress of the European Societies of Toxicology, 2023.
    10.1016/s0378-4274(23)00548-9
  10. Segovia-Zafra, Antonio; Villanueva, Marina; Serras, Ana S.; Matilla, Gonzalo; Bodoque-García, Ana; Di Zeo-Sánchez, Daniel E.; Niu, Hao; et al. "Control compounds used to validate in vitro models of idiosyncratic drug-induced liver injury: a systematic review". Paper presented in 5th Meeting of Translational Hepatology, 2023.
    10.1016/s0168-8278(23)00648-7
  11. Serras, Ana S.; Camões SP; Rodrigues JS; Vej-Nielsen JM; Vitorino R; Miranda JP. "Exosomes derived from MSCs primed with APAP injury signals reveal a pro-regenerative signature". Paper presented in 14th iMed.ULisboa Meeting, 2023.
  12. Trigo CM; Camões SP; Simões IT; Serras, Ana S.; Matos AT; Gava M; Vitorino R; et al. "Preconditioning MSCs with IFN-y enhances the neuroregenerative and immunomodulatory profile of MSC-derived secretome and exosomes". Paper presented in 14th iMed.ULisboa Meeting, 2023.
  13. Segovia-Zafra A; Villanueva-Paz M; Serras, Ana S.; Matilla-Cabello G; Bodoque A; Zeo-Sánchez D; Niu H; et al. "Control compounds used to validate in vitro models of idiosyncratic drug-induced liver injury: a systematic review". Paper presented in EASL Congress 2023, 2023.
  14. Serras, Ana S.; Camões SP; Rodrigues JS; Vej-Nielsen JM; Vitorino R; Miranda JP. "Exosomes derived from MSCs primed with APAP injury signals reveal a pro-regenerative signature". Paper presented in 2nd Meeting of the Portuguese Network on Extracellular Vesicles, 2023.
  15. Segovia-Zafra A; Villanueva-Paz M; Matilla-Cabello G; Bodoque A; Zeo-Sánchez D; Niu H; Álvarez-Álvarez I; et al. "Compuestos control utilizados para validar modelos in vitro de hepatotoxicidad idiosincrásica inducida por fármacos (DILI): una revisión sistemática". Paper presented in XVI Jornadas Científicas del CIBER de Hepáticas y Digestivas (CIBEREHD), 2022.
  16. Serras, Ana S.; Camões, S.P.; Rodrigues, J.S.; Miranda, J.P.. "Exosomes derived from primed Mesenchymal Stem Cells improve cell viability on an APAP-induced hepatic injury in vitro model". Paper presented in ICT 2022 - XVIth International Congress of Toxicology, 2022.
    10.1016/j.toxlet.2022.07.476
  17. Serras, Ana S.; Ribeiro D; Camões SP; Rodrigues JS; Miranda JP. "The mesenchymal stem cells secretome modulates APAP-induced Hepatic Injury". Paper presented in 13th iMed.ULisboa Postgraduate Students Meeting, 2022.
  18. Serras, Ana S. (B41D-2E23-CD07); Ribeiro, Daniela; Camões, Sérgio P.; Rodrigues, Joana S. (531C-FA09-7DBD); Miranda, Joana P. (001A-6278-C231). "The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Drug-induced Hepatic Injury". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapy, 2022.
  19. Serras, Ana S.; Ribeiro D; Camões SP; Rodrigues JS; Miranda JP. "The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Drug-induced Hepatic Injury". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), 2022.
Journal article
  1. Rodrigues, Joana Saraiva; Faria-Pereira, Andreia; Camões, Sérgio Póvoas; Serras, Ana Sofia; Morais, Vanessa Alexandra; Ruas, Jorge Lira; Miranda, Joana Paiva. "Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling". Frontiers in Endocrinology 13 (2023): http://dx.doi.org/10.3389/fendo.2022.1043543.
    10.3389/fendo.2022.1043543
  2. Serras, Ana S. (B41D-2E23-CD07); Camões, Sérgio P.; Antunes, Bernardo; Costa, Vera M.; Dionísio, Flávio; Yazar, Volkan; Vitorino, Rui; et al. "The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Doxorubicin-Induced Cytotoxicity: Impact in Non-Tumor Cells". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms222313072.
    10.3390/ijms222313072
  3. Serras, Ana S. (B41D-2E23-CD07); Rodrigues, Joana S. (531C-FA09-7DBD); Cipriano, Madalena; Rodrigues, Armanda V.; Oliveira, Nuno G.; Miranda, Joana P. (001A-6278-C231). "A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies". Frontiers in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.626805.
    Published • 10.3389/fcell.2021.626805
Preprint
  1. Segovia-Zafra, Antonio; Villanueva-Paz, Marina; Serras, Ana S.; Matilla-Cabello, Gonzalo; Bodoque-García, Ana; Zeo-Sánchez, Daniel Enrique Di; Niu, Hao; et al. "Control Compounds for Preclinical Drug-Induced Liver Injury Assessment: Consensus-driven systematic review by the ProEuroDILI Network". 2023. http://dx.doi.org/10.21203/rs.3.rs-3578817/v1.
    10.21203/rs.3.rs-3578817/v1
Thesis / Dissertation
  1. Serras, Ana Sofia Martins. "Células estromais mesenquimais (MSC) como agentes terapêuticos". Master, Instituto Superior de Ciências da Saúde Egas Moniz, 2014. http://hdl.handle.net/10400.26/13018.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02 Mesenchymal stem cells-derived conditioned media and exosomes exhibit neuroregenerative and immunomodulatory properties 54th Meeting of the Portuguese Society of Pharmacology, 42nd Meeting of Clinical Pharmacology and 23rd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia (Lisbon, Portugal)
2023/10 Stem cell-derived hepatocyte-like cells recapitulate cues of insulin resistance progression ETRS & SPCE-TC Joint Meeting 2023
European Tissue Repair Society (ETRS) & Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC) (Coimbra, Portugal)
2023/10 Exosomes derived from MSCs preconditioned with IFN-y and TNF-a show improved immunosuppressive and pro-regenerative effects for chronic wounds 2nd Meeting of the Portuguese Network on Extracellular Vesicles
Portuguese Network on Extracellular Vesicles
2023/02 Exosomes derived from mesenchymal stem cells primed with hepatic SOS signals carry pro-regenerative cargo 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia (SPF) (Coimbra, Portugal)
2023/02 Pro-inflammatory stimuli with INF-y and TNF-a promotes immunosupressive and tissue regenerative effects of MSC-derived exosomes 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia (SPF) (Coimbra, Portugal)
2023/02 Preconditioning MSCs with inflammatory stimuli as a promising therapeutic strategy towards neuroinflammation-mediated diseases 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia (SPF) (Coimbra, Portugal)
2022/10 As células estaminais no desenvolvimento de medicamentos Stem cell awareness day 2022
Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC)
2022/07 Towards a microphysiological stem cell-based hepatic in vitro model for studying insulin signaling pathway 13th iMed.ULisboa Postgraduate Students Meeting
Research Institute for Medicines (imed.ULisboa) (Lisbon, Portugal)
2022/02/09 The Secretome of Mesenchymal Stem Cells Ameliorates APAP-induced Hepatic Injury 52ª Reunião da Sociedade Portuguesa de Farmacologia, 40ª Reunião de Farmacologia Clínica e 21ª Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2021/10 Células estamimais no desenvolvimento de medicamentos Stem cell awareness day 2021
Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC)
2021/02/18 Glucagon Induces a More Periportal Phenotype in Hepatocyte-Like Cells 51ª Reunião Sociedade Portuguesa de Farmacologia (SPF)/39ª Reunião Farmacologia Clínica/20ª Reunião Toxicologia
Sociedade Portuguesa de Farmacologia, Faculdade de Farmácia da Universidade de Lisboa (Lisbon (online), Portugal)
2021/02/17 The Secretome of Mesenchymal Stem Cells Modulates Doxorubicin-induced Cytotoxicity 51ª Reunião Sociedade Portuguesa de Farmacologia (SPF)/39ª Reunião Farmacologia Clínica/20ª Reunião Toxicologia
Sociedade Portuguesa de Farmacologia, Faculdade de Farmácia da Universidade de Lisboa (Lisbon (online), Portugal)
2020/02/07 Hepatocyte-like Cells as a Model for Hepatotoxicity Studies 50ª Reunião Sociedade Portuguesa de Farmacologia (SPF)/38ª Reunião Farmacologia Clínica/19ª Reunião Toxicologia
Portuguese Society of Pharmacology, Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2019/10/11 Delivery of exosomes derived from 3D-cultured human neonatal mesenchymal stromal cells improves cutaneous wound healing 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
Portuguese Society for Stem Cells and Cell Therapies (Lisbon, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/10/10 - 2019/10/12 Conference staff member of the 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) (2019/10/10 - 2019/10/12)
Meeting
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Association member

Society Organization name Role
2022/01 - Current Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC) Student member
2022/01 - Current Sociedade Portuguesa de Farmacologia (SPF) Student member
2014/12/17 - Current Ordem dos Farmacêuticos Effective member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/05/01 - 2023/05/31 Analytical Chemistry - laboratory lessons Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/04/27 - 2023/04/27 Mesenchymal Stem Cells: Therapeutic, Toxicological and Disease Modelling Applications Biologia Evolutiva e do Desenvolvimento (Mestrado integrado) Universidade de Lisboa Faculdade de Ciências, Portugal

Mentoring / Tutoring

Topic Student name
2022 - 2023 Master thesis: The role of the endocannabinoid system on tissue regeneration Guilherme Pargana
2021/07 - 2021/10 Short term scientific mission: Advancing in vitro models of DILI: key techniques for the study of hepatotoxicity in cell cultures Daniel E. Di Zeo Sánchez
2017/09 - 2018/08 Professional Internship in Community Pharmacy (Dermopharmacy/Auxiliary Technician) Joana Campana
2016/03 - 2017/02 Professional Internship in Community Pharmacy (Pharmacist) Filipa Carvalho
2016/03 - 2017/02 Professional Internship in Community Pharmacy (Pharmacist) Margarida Rocha
2016/07 - 2016/10 Curricular Internship in Community Pharmacy (Pharmaceutical Sciences student) João Gonçalves
2016/03 - 2016/08 Curricular Internship in Community Pharmacy (Pharmaceutical Sciences student) Bernardo Henriques

Scientific expedition

Activity description Institution / Organization
2022/08/29 - 2022/11/04 Short-term Scientific Mission: Project entitled “Priming hnMSCs-secretome for liver injury: The role on DILI immune response” - Grant from COST Action CA17112 (PROEURO DILI NETWORK) Instituto de Investigación Biomédica de Málaga, Spain
2021/08/23 - 2021/08/25 Summer School on the Basics to Work with Extracellular Vesicles - Grant from COST Action CA16119 (CellFit) COMBIVET, Estonia

Doctoral School of Biomedicine and Biotechnology, Estonia
Distinctions

Award

2023 Top 4 Abstract at the EUROTOX Molecular Toxicology Speciality Section, at EUROTOX 2023: Exosomes derived from mesenchymal stem cells exposed to hepatic injury signals reveal a distinct protein signature associated to pro-regenerative effects
2023 SPF EUROTOX 2023 bursary, from Sociedade Portuguesa de Farmacologia, to attend EUROTOX 2023: Exosomes derived from mesenchymal stem cells exposed to hepatic injury signals reveal a distinct protein signature associated to pro-regenerative effects
Sociedade Portuguesa de Farmacologia, Portugal
2023 ETRS & SPCE-TC 2023 Conference bursary, from the SPCE-TC, for attendance at the ETRS & SPCE-TC Joint Meeting 2023: Hepatic SOS signals preconditioning modulate MSC-secretome and derived exosomes towards a more pro-regenerative profile
2023 Best Poster Award, at the 2nd Meeting of the Portuguese Network on Extracellular Vesicles: Exosomes derived from MSCs primed with APAP injury signals reveal a pro-regenerative signature
2022 STSM Grant from COST Action CA17112 Pro-EuroDILI, for a collaboration with Prof. Dr. M. Isabel Lucena, at the Biomedical Research Institute of Malaga (IBIMA): Priming hnMSCs-secretome for liver injury: The role on DILI immune response
2022 ITC Grant, from COST Action CA17112 Pro-EuroDILI, for attendance at the ICT 2022 ¿ XVI International Congress of Toxicology: Exosomes derived from primed Mesenchymal Stem Cells improve cell viability on an APAP-induced hepatic injury in vitro model
2021 Bursary, from the EUROTOX 2021 Congress Organizers, for attendance at the 56th Congress of the European Societies of Toxicology: The secretome of mesenchymal stem cells ameliorates the cytotoxic effects of doxorubicin in non-tumoral cells
2021 ITC Grant, from COST Action CA16119 CellFit, for participation on the Summer School entitled Basics to Work with Extracellular Vesicles, at the Centre of Translational Medicine at the University of Tartu

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2017 Responsible Pharmacist
Laziapho, Lda., Portugal
2016 Responsible Pharmacist
Laziapho, Lda., Portugal