Marta Alexandra Rodrigues Casanova (B71B-4CAF-F47F)

Curriculum Vitae

Marta Alexandra Rodrigues Casanova

Marta Rodrigues Casanova is a renowned researcher in Tissue Engineering, Regenerative Medicine, and Stem Cells, as well as biomedical sciences. Her education includes a Bachelor's in Biomedical Sciences from the University of Algarve, focusing on pharmacogenetics, and a Master's in Molecular Genetics from the University of Minho, where she developed a new approach for preventing and treating colorectal cancer. After completing her PhD at Minho University, she innovated in medical devices and techniques for treating bone and nerve disorders. Her work led to the development of new materials for tissue regeneration and diagnostics. Casanova continued her research at the 3B's Research Group Laboratory, working on materials science, protein engineering, and innovations to prevent infections. Her recent project involves developing new methods for targeting cancer cells and creating cost-effective technologies for detecting and evaluating colorectal cancer treatments. Her achievements include publishing 20 articles, holding two patents, contributing to a book chapter, and receiving several awards. Her research has spanned various roles, from leading projects to post-doctoral work, in areas like medical biotechnology and health sciences. Currently, Casanova is focused on developing devices and models for early colorectal cancer diagnosis and personalized medicine, aiming to make detection faster, more accurate, and widely accessible. She is also working on personalized treatments to improve patient outcomes. Casanova's collaborations worldwide have helped her access advanced technologies, significantly contributing to her field. Her dedication and innovative work are set to make a lasting impact on medical diagnostics and treatment, improving global health care. In her Ciência Vitae profile, the predominant terms reflecting Marta Rodrigues Casanova's scientific, technological, and artistic-cultural contributions include: Tissue Engineering; Regenerative Medicine; Stem Cells; Biofunctionalized Nanofibrous Substrates; Surface Biofunctionalization Techniques; Pharmacogenetics; Molecular Genetics; Biomaterials Science; Protein Engineering; Surgical Innovation; Infection Prevention and Control; Point-of-Care Technologies; Colorectal Cancer Detection and Therapy; Organ-on-a-Chip; Liquid Biopsy-on-a-Chip; Early Diagnosis; Precision Medicine; Personalized Therapies; Biomedical Sciences; Medical Device Development; and International Collaboration.

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Identification

Personal identification

Full name: Marta Alexandra Rodrigues Casanova

Citation names

Casanova, Marta R.

Author identifiers

Ciência ID: B71B-4CAF-F47F
ORCID iD: 0000-0002-9413-7977
Researcher Id: AAL-5693-2020

Email addresses

marta.casanova@i3bs.uminho.pt (Professional)

Telephones

Fax

253510909 (Professional)

Telephone

253510912 (Professional)

Addresses

3B´s Research Group . Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra , 4805-017 , Barco GMR, Guimarães, Portugal (Professional)

Websites

http://www.3bs.uminho.pt/users/martacasanova (Professional)

Knowledge fields

Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
Medical and Health Sciences - Medical Biotechnology - Biomaterials
Medical and Health Sciences - Health Sciences - Social Biomedical Sciences
Natural sciences - Biological Sciences - Cell Biology
Exact Sciences - Physical Sciences
Exact Sciences - Computer and Information Sciences - Bioinformatics
Medical and Health Sciences - Clinical Medicine - Oncology
Engineering and Technology - Industrial Biotechnology - Fermentation

Languages

Language	Speaking	Reading	Writing	Listening
Portuguese	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)
Spanish; Castilian	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)

Education

	Degree	Classification
2015/10/01 - 2020/02/20 Concluded	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Major in Substrate Biofunctionalization Universidade do Minho, Portugal "Surface biofunctionalization of polycaprolactone fibrous meshes for skeletal and neural tissue advanced therapies." (THESIS/DISSERTATION)	"Muito Bom"
2015 - 2016 Concluded	Biomateriais (Outros) I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	17
2015 - 2016 Concluded	Estratégias Avançadas em Engenharia de Tecidos (Outros) I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	19
2015 - 2016 Concluded	Nanobiomateriais (Outros) I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	16
2015 - 2016 Concluded	Células Estaminais em Medicina Regenerativa (Outros) I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2012/09 - 2015/03 Concluded	Mestrado em Genética Molecular (Mestrado) Universidade do Minho Escola de Ciências, Portugal "“Development of an improved propionibacteria for potential use as a nutraceutical towards the prevention/treatment of colorectal carcinoma” " (THESIS/DISSERTATION)	18
2012 - 2013 Concluded	Sinalização, Expressão Génica e Regulação Pós-Transcripcional (Outros) Universidade do Minho, Portugal	18
2012 - 2013 Concluded	Protein Degradation and Trafficking in Heath and Disease (Outros) Universidade do Minho, Portugal	18
2012 - 2013 Concluded	Pharmacological Development: From Organic Synthesis to Clinical Trials (Outros) Universidade do Minho, Portugal	18
2012 - 2013 Concluded	Cancer Therapy: From Basic Research to Clinic (Outros) Universidade do Minho, Portugal	18
2008/09 - 2011 Concluded	Ciências Biomédicas (Licenciatura) Universidade do Algarve, Portugal "Pharmacogenetics in Chemotherapy Response" (THESIS/DISSERTATION)	14

Affiliation

Science

	Category Host institution	Employer
2020/11/02 - 2023/06/30	Contracted Researcher (Research)	Universidade do Minho, Portugal
	I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2019/12/01 - 2020/10/31	Researcher (Research)	Universidade do Minho, Portugal
	Biomaterials Biodegradables and Biomimetics, Portugal
2015/03 - 2015/10	Researcher (Research)	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Positions / Appointments

	Category Host institution	Employer
2015/10/01 - 2019/10/30	The PhD student was selected for a PhD grant of the Doctoral Program PATH	Universidade do Minho, Portugal
	I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2014/09 - 2015/07	Laboratory assistant, Support in lab classes of the Biochemistry Bachelor, Cell Biology curricular unit	Universidade do Minho Escola de Ciências, Portugal

2013/09/30 - 2015/03/30	The MSc student work on master thesis	Universidade do Minho, Portugal

Others

	Category Host institution	Employer
2014/05 - 2014/05	Coordinator of scientific activities with children	Universidade do Minho Escola de Ciências, Portugal

2010/11 - 2011/06	Bachelor student	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Projects

Grant

	Designation	Funders
2023/01/01 - 2026/12/31	ONCOSCREEN - A European “shield” against colorectal cancer based on novel, more precise and affordable risk-based screening methods and viable policy pathways 101097036 Post-doc EXUS SOFTWARE MONOPROSOPI ETAIRIA PERIORISMENIS EVTHINIS , Greece UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ , Germany EREVNITIKO PANEPISTIMIAKO INSTITOUTO SYSTIMATON EPIKOINONION KAI YPOLOGISTON , Greece FIRALIS , France Universitätsklinikum Schleswig-Holstein, Germany UNIVERSITAET zu LUEBECK , Germany Lietuvos sveikatos mokslu universitetas, Lithuania Medizinische Universität Graz, Austria Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal INSTITUTUL ONCOLOGIC PROF. DR. ALEXANDRU TRESTIOREANU BUCURESTI, Romania Guangdong Technion-Israel Institute of Technology, China Universidade do Minho, Portugal TILBURG UNIVERSITY- UNIVERSITEIT VAN TILBURG , Ireland VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V., Belgium ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS, Greece INNOVACIONES GENETICAS SL, Spain SCIENTIFIC ACADEMY FOR SERVICE TECHNOLOGY EV, Germany AINIGMA TECHNOLOGIES , Belgium CATALINK LIMITED, Cyprus KONNEKT ABLE TECHNOLOGIES LIMITED, Ireland BEIA CONSULT INTERNATIONAL SRL, Romania Universidad de la Rioja, Spain TIMELEX, Belgium CARR COMMUNICATIONS LIMITED , Ireland Ellenike Demokratia Ypourgeio Ygeias, Greece PAGALBOS ONKOLOGINIAMS LIGONIAMS ASOCIACIJA, Lithuania EUROPACOLON PORTUGAL- ASSOCIACAO DE LUTA CONTRA O CANCRO DO INTESTINO, Portugal ELLINIKI ETAIREIA OGKOLOGIAS PEPTIKOU, Greece EUROPAISCHE VEREINIGUNG DER GASTROINTESTINALEN ONKOLOGIE(EUROPEAN SOCIETY OF DIGESTIVE ONCOLOGY - ESDO) , Austria FUNDATIA YOUTH CANCER EUROPE , Romania Landeskrankenhaus Department für Kinder- und Jugendheilkunde, Austria LIETUVOS RESPUBLIKOS SVEIKATOS APSAUGOS MINISTERIJA , Lithuania EY ADVISORY SPA , Italy Agencia Estatal Consejo Superior de Investigaciones Científicas, Spain Université de Franche-Comté, France ROZENBAUM KONSULTING, Bulgaria AXA SA, France ASSOCIATION GERCOR, France LOUWEN ROGIER , Ireland SANNE VOOGD, Ireland	European Commission Ongoing
2022/05/01 - 2023/06/30	JUSThera - Janus Approach to Cancer Theranostics NORTE-01-0145-FEDER-000055 Post-doc	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2020/11/01 - 2022/02/28	ChimericFibre4Tendon – Advanced bioinspired drug- free materials for tendon-ligament repair PTDC/BII-BIO/28870/2017 Post-doc	Fundação para a Ciência e a Tecnologia Concluded
2019/12/01 - 2020/02/29	VESCells - Single-step fabrication of biofunctional blood vessel substitutes by using electrospinning technologies and mesenchymal stem cells PTDC/BBB-BMD/5468/2014 Master Student Fellow I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015/10 - 2019/10	Doctoral program an advanced therapies for health FSE/POCH/PD/169/2013 PD/BD/113797/2015 PhD Student Fellow Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015/03 - 2015/10	RuPMC project (IF/01302/2013) IF/01302/2013 Master Student Fellow Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2022/01/01 - Current	SpyPatch - Modular spider silk and elastin recombinamers for soft tissue repair patches PTDC/BTM-MAT/2844/2021 Post-doc I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/10/01 - 2023/09/30	HEALTH-UNORTE: Setting-up biobanks and regenerative medicine strategies to boost research in cardiovascular, musculoskeletal, neurological, oncological, immunological and infectious diseases NORTE-01-0145-FEDER-000039 Post-doc	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2018/06 - 2022/06/30	Cells4_IDs: Cell-based therapy for the treatment of articular inflammatory diseases PTDC/BTM-SAL/28882/2017 Post-doc I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015/07 - 2021/12	FoReCaST - Forefront Research in 3D Disease Cancer Models as in vitro Screening Technologies 668983-FoReCaST Researcher I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal The Hebrew University of Jerusalem Department of Cognitive and Brain Sciences, Israel University of Cambridge Computer Laboratory, United Kingdom Universiteit Maastricht Department of International Health, Netherlands Hubrecht Institute, Netherlands Candiolo Cancer Institute, Italy IRCCS Ospedale Policlinico San Martino, Italy	European Commission Concluded
2016/10 - 2020/07	FROnTHERA - Frontiers of technology for theranostics of cancer, metabolic and neurodegenerative diseases NORTE-01-0145-FEDER-000023 PhD Student Fellow I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal International Iberian Nanotechnology Laboratory, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2016/05 - 2019/11	SPARTAN - Preclinical Validation of a TNF-Capturing Device as Therapeutics of Inflammatory Arthritic Diseases PTDC/CTM-BIO/4388/2014 PhD Student Fellow I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book chapter	Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "The Use of Electrospinning Technique on Osteochondral Tissue Engineering". In Advances in Experimental Medicine and Biology, 247-263. Springer International Publishing, 2018. Published • 10.1007/978-3-319-76711-6_11
Conference abstract	Casanova, Marta R.; Franco A. R.; Martins A.; Leonor I. B.; Reis R. L.. "Bioengineered spider silk immobilized on a nanofibrous mesh inhibit bacteria adherence and anticipate new prospects for abdominal muscle tissue repair". Paper presented in TERMIS European Chapter Meeting 2023, Manchester, 2023. MOTA, PAULO; Casanova, Marta R.; Vala, Helena; Nóbrega, Carmen ; da Silva Morais, Alain; Silva, Catarina Santos; Anacleto, Sara; et al. "Bioactive Fibrous Membrane Containing Endogenous Nerve Growth Factor Promotes Celular and Functional Recuperation of Impaired Cavernous Nerve: An In Vivo Animal Study.". Paper presented in American Urological Association Annual Meeting, New Orleans, 2022. Published • https://doi.org/10.1097/JU.0000000000002592.01 Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenic Inductive Nanofibrous Mesh Biofunctionalized with Human Fibronectin". Paper presented in Society For Biomaterials 2019 Annual Meeting, 2019. https://abstracts.biomaterials.org/data/papers/2019/abstracts/961.pdf Casanova, Marta R.; Fernandes, Emanuel M.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Parallel binding of autologous BMP-2 and VEGF envisioning a vascularized bone tissue engineering approach". Paper presented in 45th ESAO Congress, Madrid, 2018. doi.org/10.1177/0391398818785526 Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenesis-inductive nanofibrous substrate biofunctionalized with autologous growth factors from platelet lysates for stem cell based therapies". Paper presented in TERMIS EU, 2017. https://ecmconferences.org/abstracts/2017/Collection2/pdf/collection2_poster.pdf Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenic-Inductive Nanofibrous Substrates Biofunctionalized with Immobilized Autologous TGF-b3 and IGF-I". Paper presented in Transactions of the Society For Biomaterials 2017 Annual Meeting, 2017. https://abstracts.biomaterials.org/data/papers/2017/abstracts/0700.pdf Casanova, Marta R.; Preto, Ana; Rodrigues, Ligia R.. "Improved production of acetate and propionate by Propionibacterium freudenreichii". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014. https://www.ceb.uminho.pt/bridge/Publications/Details/19677
Conference paper	Casanova, M.R.; Reis, R.L.; Martins, A.; Neves, N.M.. "Chondrogenic inductive nanofibrous mesh biofunctionalized with human fibronectin". 2019.
Conference poster	Franco A. R.; Casanova, Marta R.; Martins A.; Leonor I. B.; Reis R. L.. "Immobilized bioengineered spider silk ion a nanofibrous mesh reduces bacteria adhesion while improving abdominal muscle tissue repair". Paper presented in REMIX Final Workshop, 2023. Casanova, Marta R.; Oliveira, J. M.; Reis, R. L.. "Design and technological approaches for the detection and isolation of Circulating Tumor Cells". Paper presented in REMIX Final Workshop, 2023. Franco A. R.; Casanova, Marta R.; Cruz-Moreira D.; Martins A.; Neves N. M.; Leonor I. B.; Reis R. L.. "Functionalization of surgical meshes with bioengineered spider silk proteins to impair surgical site infections". Paper presented in TERMIS European Chapter Conference 2022, 2022. Casanova, Marta R.; Mota P.; Vala H.; Nóbrega C.; da Silva Morais A.; Silva C. S.; Barros, A. A.; et al. "MP38-01: Bioactive fibrous membrane containing endogenous nerve growth factor promotes cellular and functional recuperation of impaired cavernous nerve: an in vivo animal study". Paper presented in American Urological Association Annual Meeting - 2022, 2022. Casanova, Marta R.; Mota P.; Vala H.; Nóbrega C.; da Silva Morais A.; Silva C. S.; Barros, A. A.; et al. "Cellular and Functional Recuperation of Impaired Cavernous Nerve Mediated by a Personalized Cell-free Fibrous Bioimplant". Paper presented in Final Achilles Conference and MIcSeaOnMed Workshop, 2022. Mendanha, D; Vieira de Castro, J.; Casanova, Marta R.; Gimondi, S.; Ferreira, H.; Neves, N. M.. "Macrophage cell membrane biomimetic liposomes for glioblastoma targeting therapy". Paper presented in Final Achilles Conference and MIcSeaOnMed Workshop, 2022. Casanova, Marta R.; MOTA, PAULO; Vala, Helena; Nóbrega, Carmen ; da Silva Morais, Alain; Silva, Catarina Santos; Barros, Alexandre; et al. "Cellular and Functional Recuperation of Impaired Cavernous Nerve Mediated By a Personalized Cell-free Fibrous Implant". Paper presented in Final Achilles Conference, 2022. Albina Cristina Ribeiro Franco; Casanova, Marta R.; Neves, Nuno M.; Leonor, Isabel B.; Reis, Rui L.; Martins, A. "Exploitation of the potential of the functionalization of surgical meshes with bioengineered spider silk proteins to impair surgical site infections". Paper presented in Tissue Engineering International Regenerative Medicine Society - European Chapter Meeting (TERMIS-EU), 2022. Casanova, Marta R.; Mota P.; Vala H.; Nóbrega C.; da Silva Morais A.; Silva C. S.; Barros, A. A.; et al. "A Personalized Bioactive Fibrous Membrane Capable to Promote the Functional Recovery of Injured Cavernous Nerve". Paper presented in Third Achilles Workshop and Final FoReCaST Conference, 2021. Monteiro N. O.; Casanova, Marta R.; Quinteira R.; Fangueiro J. F.; Reis R. L.; Neves N. M.. "Biomimetic Surface Topography as a Potential Modulator of Macrophages Inflammatory Response to Implanted Biomaterial Scaffolds". Paper presented in Third Achilles Workshop and Final FoReCaST Conference, 2021. Tas S.; Casanova, Marta R.; Rodrigues L.; Reis R. L.; Martins A.; Neves N. M.. "Development of a Bioactive Fibrous Scaffold with Osteoinductive Properties". Paper presented in Third Achilles Workshop and Final FoReCaST Conference, 2021. Casanova, Marta R.; Reis, R. L.; Martins, A.; Neves, N. M.. "Chondrogenesis-inductive Systems Comprising Extracellular Vesicles Derived from Chondrocytic Cells". Paper presented in 2nd Achilles Conference and TERM STEM 2019, 2019. Casanova, Marta R.; Reis, Rui L.; Martins, Albino. "Autologous NGF Immobilized at the Surface of a Nanofibrous Mesh for Guided Nerve Regeneration". Paper presented in 1st Discoveries Forum on Regenerative and Precision Medicine, 2019. Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Autologous NGF Immobilized on a Nanofibrous Substrate as an Approach to Guided Nerve Regeneration". Paper presented in Achilles Conference and FoReCaST Workshop, 2019. Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenic Inductive Nanofibrous Mesh Biofunctionalized with Human Fibronectin". Paper presented in Society for Biomaterials Annual Meeting and Exposition 2019, 2019. Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Endogenous fibronectin bound to nanofibrous substrate is able to conduct the chondrogenesis of mesenchymal stem cells". Paper presented in GENE2SKIN and CHEM2NATURE FINAL CONFERENCE, 2018. Casanova, Marta R.; Fernandes, Emanuel M.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Adjacent immobilization of autologous BMP-2 and VEGF envisioning a vascularized bone tissue engineering approach". Paper presented in 29th Annual meeting of the European Society for Biomaterials (ESB), 2018. Casanova, Marta R.; Fernandes, Emanuel M.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Vascularized bone tissue engineered system comprising autologous growth differentiation factors and mesenchymal stem cells". Paper presented in 5th TERMIS World Congress, 2018. https://www2.convention.co.jp/termis-wc2018/pdf/s_poster3.pdf Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Personalized advanced therapies for skeletal tissue regeneration". Paper presented in Ciência 2018 - Encontro com a Ciência e Tecnologia em Portugal, 2018. Casanova, Marta R.; Fernandes, Emanuel M.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Vascularized bone tissue engineered platform comprising autologous BMP-2 and VEGF parallel immobilized". Paper presented in Winter School Gene2Skin and 1o Workshop do FoReCaST -The Tumour Microenvironment, 2017. Alves da Silva, Marta; Costa-Pinto, Ana R.; Casanova, Marta R.; Reis, Rui L.; Nogueira-Silva, Cristina; Neves, Nuno M.. "Isolation methods of human and bovine adipose tissue derived stem cells". Paper presented in Winter School Gene2Skin and 1o Workshop do FoReCaST -The Tumour Microenvironment, 2017. Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenesis-inductive nanofibrous substrate biofunctionalized with autologous growth factors from platelet lysates for stem cell-based therapies". Paper presented in TERMIS-EU 2017 Conference, 2017. Casanova, Marta R.; Fernandes, Emanuel M.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Adjacent immobilization of autologous BMP-2 and VEGF envisioning a vascularized bone tissue engineering approach". Paper presented in CHEM2NATURE Second School, 2017. Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino. "Chondrogenic-Inductive Nanofibrous Substrates Biofunctionalized with Immobilized Autologous TGF-b3 and IGF-I". Paper presented in Society for Biomaterials 2017Annual Meeting and Exposition, 2017. Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenesis-inductive nanofibrous substrate comprising autologous TGF-b3 and IGF-I from platelet lysates". Paper presented in GENE2SKIN Conference & TERM STEM, 2016. Casanova, Marta R.; Rodrigues, Ligia R.; Preto, Ana. "Propionibacterium freudenreichii short-chain fatty acids inhibit the proliferation of colorectal cancer cells". Paper presented in XXXIX Portuguese Genetics Conference, 2015. Casanova, Marta R.; Rodrigues, Ligia R.; Preto, Ana. "Short chain fatty acids produced by Propionibacterium freudenreichii inhibit colorectal cancer cells survival". Paper presented in XXIII Porto Cancer Meeting - Stem Cells and Cancer, 2015. Casanova, Marta R.; Preto, Ana; Rodrigues, Ligia R.. "Improved production of acetate and propionate by Propionibacterium freudenreichii". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014. Casanova, Marta R.; Preto, Ana; Rodrigues, Ligia R.. "Propionibacterium freudenreichii as a producer of acetate and propionate". Paper presented in II Symposium of the PhD Programme on Molecular and Environmental Biology, 2014.
Journal article	Casanova, Marta R.; Carvalho, M. R.; Oliveira, J; Oliveira, J. M.; Reis, R. L.. "Electrospinning Technology for Enhanced Capture and Efficiency of Circulating Tumor Cells: Designing Fiber Networks for Improved Detection and Isolation". (2023): Submitted Casanova, Marta R.; Franco A. R.; Martins A.; Leonor I. B.; Reis, R. L.. "Spider Silk-Based Nanofibrous Meshes: A Promising Bioengineering Approach for Preventing Bacterial Adhesion and Improving Abdominal Muscle Tissue Repair". (2023): Submitted Casanova, Marta R.; Oliveira, J. M.; Reis, R. L.. "Recent Advances and Future Directions in Detection and Isolation of Circulating Tumor Cells (CTCs): A Comprehensive Review". (2023): Submitted Paulo Mota; Helena Vala; Carmen Nóbrega; A. da Silva Morais; Catarina S. Silva; Alexandre A. Barros; Rui L. Reis; et al. "Functional recovery of injured cavernous nerves achieved through endogenous nerve growth factor-containing bioactive fibrous membrane". Acta Biomaterialia 168 (2023): 416-428. http://dx.doi.org/10.1016/j.actbio.2023.07.015. 10.1016/j.actbio.2023.07.015 Marta R. Casanova; Hugo Osório; Rui L. Reis; Albino Martins; Nuno M. Neves. "Author Correction: Chondrogenic differentiation induced by extracellular vesicles bound to a nanofibrous substrate". npj Regenerative Medicine (2023): https://doi.org/10.1038/s41536-023-00300-8. 10.1038/s41536-023-00300-8 Monteiro, N O; Casanova, M R; Fangueiro, J F; Reis, R L; Neves, N M. "The biomimetic surface topography of Rubus fruticosus leaves stimulate the induction of osteogenic differentiation of rBMSCs". Biomedical Materials 18 3 (2023): 035008. http://dx.doi.org/10.1088/1748-605x/acc55f. Published • 10.1088/1748-605x/acc55f Mendanha, D.; Vieira de Castro, J.; Casanova, Marta R.; Gimondi, S.; Ferreira, H.; Neves, N.M.. "Macrophage cell membrane infused biomimetic liposomes for glioblastoma targeted therapy". Nanomedicine: Nanotechnology, Biology and Medicine 49 (2023): 102663. http://dx.doi.org/10.1016/j.nano.2023.102663. Published • 10.1016/j.nano.2023.102663 Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Neves, Nuno M.; Nogueira-Silva, Cristina. "Human Amniotic Membrane Stem Cells Isolation and Characterization". (2023): Submitted Tas S.; Casanova, Marta R.; Rodrigues L.; Reis R. L.; Martins A.; Neves N. M.. "Development of a Bioactive Fibrous Scaffold with Osteoinductive Properties". (2023): Submitted Monteiro, N.O.; Casanova, Marta R.; Quinteira, R.; Fangueiro, J.F.; Reis, R.L.; Neves, N.M.. "Biomimetic surface topography as a potential modulator of macrophages inflammatory response to biomaterials". Biomaterials Advances 141 (2022): 213128. http://dx.doi.org/10.1016/j.bioadv.2022.213128. Published • 10.1016/j.bioadv.2022.213128 Mota, Paulo; Casanova, Marta R.; Vala, Helena; Nóbrega, Carmen; Morais, Alain; Silva, Catarina; Anacleto, Sara; et al. "BIOACTIVE FIBROUS MEMBRANE CONTAINING ENDOGENOUS NERVE GROWTH FACTOR PROMOTES CELLULAR AND FUNCTIONAL RECUPERATION OF IMPAIRED CAVERNOUS NERVE: AN IN VIVO ANIMAL STUDY". Journal of Urology 207 Supplement (2022): http://dx.doi.org/10.1097/ju.0000000000002592.01. 10.1097/ju.0000000000002592.01 Mota, Paulo; Casanova, Marta; Vala, Helena; Nobrega, Carmen; Morais, Alain; Silva, Catarina; Anacleto, Sara; et al. "BIOACTIVE FIBROUS MEMBRANE CONTAINING ENDOGENOUS NERVE GROWTH FACTOR PROMOTES CELLULAR AND FUNCTIONAL RECUPERATION OF IMPAIRED CAVERNOUS NERVE: AN IN VIVO ANIMAL STUDY". Journal of Urology (2022): https://publons.com/wos-op/publon/54571906/. Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Stimulation of Neurite Outgrowth Using Autologous NGF Bound at the Surface of a Fibrous Substrate". Biomolecules 12 1 (2021): 25. http://dx.doi.org/10.3390/biom12010025. Published • 10.3390/biom12010025 Casanova, Marta R.; Osório, Hugo; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenic differentiation induced by extracellular vesicles bound to a nanofibrous substrate". npj Regenerative Medicine 6 1 (2021): http://dx.doi.org/10.1038/s41536-021-00190-8. 10.1038/s41536-021-00190-8 Gomes, Sara Daniela; Oliveira, Cláudia Suellen; Azevedo-Silva, João; Casanova, Marta R.; Barreto, Judite; Pereira, Helena; Chaves, Susana R.; et al. "The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications". Current Medicinal Chemistry 27 24 (2020): 4087-4108. http://dx.doi.org/10.2174/0929867325666180530102050. 10.2174/0929867325666180530102050 Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Fibronectin Bound to a Fibrous Substrate Has Chondrogenic Induction Properties". Biomacromolecules 21 4 (2020): 1368-1378. http://dx.doi.org/10.1021/acs.biomac.9b01546. 10.1021/acs.biomac.9b01546 Casanova, Marta R.; Oliveira, Catarina; Fernandes, Emanuel M.; Reis, Rui L.; Silva, Tiago H.; Martins, Albino; Neves, Nuno M.; et al. "Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineering". Biomaterials Science 8 9 (2020): 2577-2589. http://dx.doi.org/10.1039/d0bm00087f. 10.1039/d0bm00087f Casanova, Marta R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.; Marta R. Casanova; Rui L. Reis; Albino Martins; Nuno M. Neves. "Surface biofunctionalization to improve the efficacy of biomaterial substrates to be used in regenerative medicine". Materials Horizons 7 9 (2020): 2258-2275. http://dx.doi.org/10.1039/d0mh00542h. 10.1039/d0mh00542h Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenesis-inductive nanofibrous substrate using both biological fluids and mesenchymal stem cells from an autologous source". Materials Science and Engineering: C 98 (2019): 1169-1178. http://dx.doi.org/10.1016/j.msec.2019.01.069. 10.1016/j.msec.2019.01.069 Casanova, Marta R.; Azevedo-Silva, João; Rodrigues, Ligia R.; Preto, Ana. "Colorectal Cancer Cells Increase the Production of Short Chain Fatty Acids by Propionibacterium freudenreichii Impacting on Cancer Cells Survival". Frontiers in Nutrition 5 (2018): http://dx.doi.org/10.3389/fnut.2018.00044. Published • 10.3389/fnut.2018.00044
Thesis / Dissertation	Casanova, Marta R.. "Surface biofunctionalization of polycaprolactone fibrous meshes for skeletal and neural tissue advanced therapies". PhD, Universidade do Minho, 2020. Casanova, Marta. "Development of an improved propionibacterium for potential use as a nutraceutical towards the prevention - treatment of colorectal cancer". Master, 2015. http://hdl.handle.net/1822/35685. Casanova, Marta R.. "Pharmacogenetics in Chemotherapy Response". Degree, Universidade do Algarve Centro de Investigação em Biomedicina, 2011.

Intellectual property

Patent

Casanova, Marta R.; Martins A.; Mota P.; Reis R. L.; Neves N. M.; Dias, E. C.; Barros A.. 2021. "Polimeric substrates for nerve regeneration, methods and uses thereof".
Granted/Issued
Casanova, Marta R.; Albino Martins; Mota, Paulo; Reis, Rui L.; Neves, Nuno M.; Carvalho Dias, Emanuel; Barros, Alexandre. 2020. "POLIMERIC SUBSTRATES FOR NERVE REGENERATION, METHODS AND USES THEREOF". Portugal.
Granted/Issued

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/03	Bioengineered spider silk immobilized on a nanofibrous mesh inhibit bacteria adherence and anticipate new prospects for abdominal muscle tissue repair	TERMIS European Chapter Meeting 2023 TERMIS European (Manchester, United Kingdom)
2021/05/11	"Biofuncionalização de superficies"	VII Jornadas de Química e Bioquímica Universidade da Beira Interior (Portugal)
2020/12	Chondrogenesis-inductive Nanofibrous Substrate Comprising Extracellular Vesicles Derived from Chondrocytic Cells	WBC2020 World Biomaterials Committee (Scotland, United Kingdom)
2018/09	Parallel binding of autologous BMP-2 and VEGF envisioning a vascularized bone tissue engineering approach	XLV ESAO Congress (Madrid, Spain)
2018/06	Nanofibrous substrate functionalized with fibronectin is able to conduct the chondrogenesis of mesenchymal stem cells	CHEM2NATURE (Porto, Portugal)
2016/11	Chondrogenesis-inductive nanofibrous substrate comprising autologous TGF-b3 and IGF-I from platelet lysates	CHEM2NATURE First School (Guimarães, Portugal)
2014/11	Propionibacterium freudenreichii as a producer of acetate and propionate	II Symposium of the PhD Programme on Molecular and Environmental Biology (Braga, Portugal)

Event organisation

	Event name Type of event (Role)	Institution / Organization
2021/10 - 2021/10	Third Achilles Workshop and Final FoReCaST Conference (2021/10) Conference (Member of the Organising Committee)	Universidade do Minho, Portugal Laboratório Associado ICVS 3B's, Portugal
2021/06 - 2021/06	TERM STEM 2021 (2021/06) Conference (Member of the Organising Committee)	Universidade do Minho, Portugal Laboratório Associado ICVS 3B's, Portugal
2018/12 - 2018/12	Interactive exposition at "GALERIA DE ARTES E OFÍCIOS DE AMARES" (2018/12) Exhibition	Laboratório Associado ICVS 3B's, Portugal
2018/11 - 2018/11	Scientific Photo Exposition at “Centro Ciência Viva” (2018/11)	Laboratório Associado ICVS 3B's, Portugal
2018/10 - 2018/11	Scientific Photo Exposition at FNAC Braga (2018/10)	Laboratório Associado ICVS 3B's, Portugal
2017/06 - 2017/06	Chem2Nature Second School Conference (2017/06 - 2017/06)	Laboratório Associado ICVS 3B's, Portugal
2016/11 - 2016/11	Chem2Nature First School Conference (2016/11 - 2016/11)

Event participation

	Activity description Type of event	Event name Institution / Organization
2020/09/23 - 2020/09/23	Training and certification for working with Countess Other	Countess I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2020/02/06 - 2020/02/06	Training seminar on Quality System ISO 9001:2015 Seminar	Quality Management System on ISO 9001:2015 I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2018/07 - 2018/07	Horizon 2020 Entrepreneurship for Researchers Workshop
2016/06/08 - 2016/06/08	Training/certification for working with/on PCR lab Other	PCR I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2016/04/27 - 2016/04/27	Training for working with/on Cell Culture Lab (CCL) Other	Cell Culture Lab (CCL) I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2016/02/22 - 2016/02/22	Training and certification for working with/on Transmitted and Reflected Light Microscope with Apotome 2. Other	Transmitted and Reflected Light Microscope I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2010 - 2016	English course	Wall Street English, United States
2015/10/20 - 2015/10/20	Training and certification for working with/on Electrospinning Other	Electrospinning I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
2014 - 2014	Workshop "Eppendorf Micropipettes"	Universidade do Minho, Portugal
2013 - 2013	Protein Degradation and Trafficking in Health and Disease	Universidade do Minho, Portugal
2013 - 2013	Pharmacological Development: From Organic Synthesis to Clinical Trials	Universidade do Minho, Portugal
2013 - 2013	Cancer Therapy: From Basic Research to Clinic	Universidade do Minho, Portugal
2012 - 2012	Initial Pedagogical Training of Trainers	Cefolgest – Formação e Consultoria, LDA, Portugal
2011 - 2011	Basic Life Support course	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Association member

	Society Organization name	Role
2023 - Current	European Association for Cancer Research (EACR)	Postdoctoral researcher
2019/12/31 - Current	Tissue Engineering and Regenerative Medicine International Society
2018/09 - Current	yESAO member

Committee member

	Activity description Role	Institution / Organization
2018/09 - 2020/02	PhDynamics Program Coordinator	Laboratório Associado ICVS 3B's, Portugal

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2023/04 - Current	“Apendiz por um dia”	(Ensino básico 3º ciclo)
2022/12 - Current	SAW Program: Colégio do Ave	(Ensino secundário)
2021 - Current	ANEM Estágio Cien1fico	(Curso de Especialização Tecnológica)
2014/06 - 2014/06	Cancer Therapy: From Basic Research to Clinic	Genética Molecular (Mestrado integrado)	Universidade do Minho, Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2022 - Current	Frontiers in Bioengineering and Biotechnology
2022 - Current	International Journal of Molecular Sciences
2022 - Current	ACS Journals	Americal Chemical Society
2021/06 - Current	Journal of Agricultural and Food Chemistry (1520-5118)	ACS Publications
2021/04 - Current	Sciences Advanced (2375-2548)	American Association for the Advancement of Science
2021 - Current	ACS Omega
2020/05 - Current	ACS Applied Materials & Interfaces (1944-8252)	American Chemical Society Publications
2017/04 - Current	Journal of Bioactive and Compatible Polymers (1530-8030)	Sage Publications

Mentoring / Tutoring

	Topic	Student name
2021/06 - Current	Real-time PCR analysis	Daniel Mendanha (PhD)
2021/03 - Current	Cell culture practices and analysis	Sellin Tas (PhD)
2020/04 - 2023	Real-time PCR analysis	Nelson O. Monteiro (PhD)
2019/08 - 2023	Cell culture practices and analysis	Catarina Silva (PhD)
2021/08/01 - 2021/08/31	Tissue Engineering and Regenerative Medicine	Bruna
2018/05 - 2019/10	Statistical analysis - SPSS	Cátia Sofia Oliveira (MSc)
2018/02 - 2018/10	Statistical analysis - SPSS	Ariana Silva (MSc)

Distinctions

Award

2019	Quiz Time organized as part of the First Achilles Conference, 1st edition – “Molecular and Biological Mechanisms of Tendon Homeostasis and Repair”
2018	Contest CHEM2BRAIN organized as part of the CHEM2NATURE Summer School, 3th edition
2014	Poster award II Symposium of the PhD Programme on Molecular and Environmental Biology, Portugal