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Mariana Bento has been part of the BioNanoCiências group of the Medicine Research Institute (iMed.Ulisboa) since 2018, developing polymeric nanoparticles for immunotherapy of various types of cancer. She completed the Integrated Master's degree in Pharmaceutical Sciences at the Faculty of Pharmacy of the University of Lisbon in 2020, after which she worked as a pharmacist in Community Pharmacy. In October 2021 she started her PhD in Pharmacy, in the specialty of Pharmaceutical Technology at the same institution. Her work consists of the development of a nanoplatform to modulate the interaction between immune cells-vasculature-tumor for the treatment of pancreatic cancer.
Identification

Personal identification

Full name
Mariana Santos Bento
Date of birth
1997/11/29
Gender
Female

Citation names

  • Bento, Mariana

Author identifiers

Ciência ID
B815-B6EA-63B9
ORCID iD
0000-0001-6005-9926

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Engineering and Technology - Medical Engineering - Medical Engineering
  • Engineering and Technology - Nano-technology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Italian Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2021/10/01 - 2025
Ongoing
Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/01/01 - 2022/09/30
Concluded
Ciências em Animais de Laboratório - Categoria B (Pós-Graduação)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
19
2015/09 - 2020/12/11
Concluded
Pharmaceutical Sciences (Mestrado integrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Development and Characterization of Delivery Systems" (THESIS/DISSERTATION)
15
Affiliation

Science

Category
Host institution
Employer
2023/03/01 - 2023/10/31 Visiting Researcher (Research) Eberhard Karls Universität Tübingen, Germany
Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen, Germany
2022/06/01 - 2022/06/30 Visiting Researcher (Research) Centro de Investigación Príncipe Felipe, Spain
2020/02/01 - 2020/04/30 Research Trainee (Research) Università degli Studi di Torino Dipartimento di Scienza e Tecnologia del Farmaco, Italy
Università degli Studi di Torino Dipartimento di Scienza e Tecnologia del Farmaco, Italy

Others

Category
Host institution
Employer
2021/03/01 - 2022/12/31 Mentor Universidade de Lisboa, Portugal
Universidade de Lisboa, Portugal
2020/10/01 - 2021/09/30 Pharmacist Farmácia Guerra Rico, Portugal
2020/06/01 - 2020/09/30 Internship in Community Pharmacy Farmácia Guerra Rico, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/04/15 - 2020/05/31 Volunteer Work Centro Hospitalar Universitário Lisboa Central, EPE, Portugal
Ordem dos Farmaceuticos, Portugal
2019/09/01 - 2019/12/31 Internship in Infarmed Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2018/07/16 - 2018/07/27 Internship in Community Pharmacy Farmácia Silveira, Portugal
Projects

Grant

Designation Funders
2020/02/01 - 2020/04/30 Development and Characterization of Delivery Systems
NA
Erasmus
Universidade de Lisboa Faculdade de Farmácia, Portugal

Università degli Studi di Torino Dipartimento di Scienza e Tecnologia del Farmaco, Italy
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluded

Contract

Designation Funders
2018/09/01 - 2020/09/30 Modulation of melanoma-stroma interaction using the BRAFi, and MEKi nanomedicines and immunotherapies
ENMed/0051/2016
Volunteer Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/11/01 - 2017/07/31 Comparing the spectral components of laser Doppler flowmetry and photoplethysmography signals for the assessment of the vascular response to hyperoxia
UID/DTP/04567/2016
Volunteer Researcher
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Journal article
  1. Carreira, Barbara; Acúrcio, Rita C.; Matos, Ana I.; Peres, Carina; Pozzi, Sabina; Vaskovich-Koubi, Daniella; Kleiner, Ron; et al. "Nanomedicines as Multifunctional Modulators of Melanoma Immune Microenvironment". Advanced Therapeutics 4 1 (2020): 2000147. http://dx.doi.org/10.1002/adtp.202000147.
  2. Silva, Henrique; Bento, Mariana; Vieira, Helena; Monteiro Rodrigues, Luis. "Comparing the spectral components of laser Doppler flowmetry and photoplethysmography signals for the assessment of the vascular response to hyperoxia". Journal Biomedical and Biopharmaceutical Research 14 2 (2017): 187-194. http://dx.doi.org/10.19277/bbr.14.2.161.
Thesis / Dissertation
  1. Bento, Mariana. "Development and Characterization of Delivery Systems". Master, Universidade de Lisboa Faculdade de Farmácia, 2020.
  2. Bento, Mariana. "Development of Polysaccharide-Based Biodegradable Nanovaccines for Dendritic Cell Targeting". Master, Universidade de Lisboa Faculdade de Farmácia, 2019.
  3. Bento, Mariana. "Optimization of Polymeric based- Nanovaccines for Dendritic Cell Targeting". Degree, Universidade de Lisboa Faculdade de Farmácia, 2019.
Activities

Event organisation

Event name
Type of event (Role)
Institution / Organization
2020/09/01 - Current ULisses Project - Oceans without plastic The main goal of this project is the development of innovative technological solutions to characterize and mitigate ocean pollution by plastics, ensuring biodiversity and sustainable reuse of these materials in applications with economic value. (2021/03/22)
Other (Member of the Organising Committee)
Universidade de Lisboa , Portugal

UNITE - University Network for Innovation, Technology and Engineering, Germany
2018/01/15 - 2018/10/27 «A Evolução da (cons)Ciência» was the theme of the 2018 AEFFUL Congress. This event aimed to reflect and discuss the most varied bioethical problems, demonstrating that health decisions are not always clear and easy to take. Several topics went under debate, including the equality of access to health, medical confidentiality and big data. (2018/10/26 - 2018/10/27)
Congress (Member of the Organising Committee)
Associação dos Estudantes da Faculdade de Farmácia da Universidade de Lisboa (AEFFUL), Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2020/03/01 - 2020/07/10 INSPIRED 2020 was a project where, as part of a dynamic team of young researchers and (bio-)engineers, we were tasked with a manufacture design of a functional, sustainable, and efficient bioreactor concept to sustain a crew stationed in Mars.
Other
Inspired 2020 Project
Technische Universitat Darmstadt, Germany

UNITE - University Network for Innovation, Technology and Engineering, Germany
2020/02/01 - 2020/04/30 In the Erasmus Traineeship Mobility Program I joined Professor Roberta Cavalli’s group to compare the immune-mediated effect induced by the polymeric based nanoparticle with the one triggered by cyclodextrin-based nanosponges. These nanocarriers were to be applied for the immunotherapy of melanoma skin cancer.
Other
Erasmus Traineeship Mobility
Università degli Studi di Torino Dipartimento di Scienza e Tecnologia del Farmaco, Italy
2019/10/14 - 2019/10/28 Public Speaking Course by Speak and Lead.
Workshop
Public Speaking Course
Speak and Lead, Portugal
2017/10/17 - 2017/10/17 Basic Life Support Course - development of skills to the perform of basic life support maneuvers in situations of cardiorespiratory arrest.
Workshop
Basic Life Support Course
Conselho Português de Ressuscitação, Portugal

European Resuscitation Council, Belgium
2016/10/15 - 2017/03/15 Uriage Schools Project «Acneic Skin Care» - training actions on acneic skincare in 3rd cycle schools.
Seminar
Uriage Schools Project «Acneic Skin Care»
Laboratoires Dermatologiques d'Uriage, France
2013/07/15 - 2013/07/19 Internship in «Tecnologias de Química na Saúde» - Ciência Viva Program: scientific occupation of young people on Summer.
Other
Ciência Viva no Laboratório - Ocupação Cientifica dos Jovens nas Férias
Universidade Lusófona, Portugal

Ciência Viva, Portugal

Association member

Society Organization name Role
2018/09/01 - Current Portuguese Pharmacists Association Full-member (2021-present); Student-member (2018-2020)
2018/01/05 - 2018/12/15 Departamento de Inovação e Ciência of the Associação dos Estudantes da Faculdade de Farmácia da Universidade de Lisboa. Member

Committee member

Activity description
Role
Institution / Organization
2022/09/01 - 2024/02/29 Member of the Young Scientific Committee (YSC) of the Spain Portuguese Local Chapter from the Controlled Release Society (SPLC-CRS). We organized the 4th SPLC-CRS Young Scientists Meeting that that took place on February 2023 in Porto, Portugal
Member
Spanish Portuguese Local Chapter, Controlled Release Society, Spain
2018/09/01 - 2020/11/26 Student's representative (elected) of Faculdade de Farmácia of the Universidade de Lisboa's board.
Member
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/09/01 - 2020/07/31 Student Representative (elected) - member of the Comissão de Curso of the Integrated Master's degree in Pharmaceutical Sciences (Faculty of Pharmacy, University of Lisbon, Portugal) during the academic years of 2016/17, 2017/18, 2018/19 and 2019/20.
Other
Universidade de Lisboa Faculdade de Farmácia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2017/09/01 - 2019/01/31 Mentoring of practical classes of the Human Physiology Course in the academic years 2017/18 and 2018/19. Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal

Mentoring / Tutoring

Topic Student name
2016/09/01 - 2019/07/31 Explanations of Mathematics, Natural Sciences, Physico-Chemical Sciences and English. Elementary School Students
Distinctions

Other distinction

2020 INSPIRED 2020 Project
Technische Universitat Darmstadt, Germany