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LUIS DANIEL MACHADO CRISÓSTOMO. Completed the Doutoramento in Ciências Biomédicas in 2022/03 by Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Mestrado in Ciências Biomédicas in 2013/07/23 by Universidade da Beira Interior Faculdade de Ciencias da Saude, Licenciatura in Ciências Biomédicas in 2011/07/08 by Universidade da Beira Interior Faculdade de Ciencias da Saude, Graduado in Nature Masterclass - Effective collaboration in Research in 2021/08/19 by Springer Nature, Graduado in Practical Peer-Review course in 2019/05/13 by Publons Academy and Graduado in Scientific Writing and Communication Seminar in 2020/04/15 by Universitetet i Bergen. Is Postdoc in Turun yliopisto lääketieteellinen tiedekunta. Published 25 articles in journals. Has 2 section(s) of books. Organized 3 event(s). Co-supervised 1 MSc dissertation(s). Co-supervised 2 work(s) of course completion of LSc/BSc. Has received 15 awards and/or honors. Participates and/or participated as Master Student Fellow in 1 project(s), PhD Student Fellow in 2 project(s) and Researcher in 2 project(s). Works in the area(s) of Natural sciences with emphasis on Biological Sciences, Natural sciences with emphasis on Biological Sciences, Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics, Medical and Health Sciences with emphasis on Basic Medicine, Medical and Health Sciences with emphasis on Basic Medicine, Medical and Health Sciences with emphasis on Basic Medicine and Natural sciences with emphasis on Biological Sciences with emphasis on Cell Biology. In their professional activities interacted with 893 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Diabetes; Obesidade; Epigenética; Fertilidade masculina; Glutationa S-Transferases; Stress oxidativo - Treino desportivo; Espécies reactivas de oxigénio; Expressão génica; metabolism; obesity; Metabolómica; Stress oxidativo; Doenças metabólicas; Espermatogénese; Efeitos transgeracionais; Transmissão paternal; High-fat diet; Sperm quality; Diet reversion; Metabolomics; Lipidomics; Parâmetros espermáticos; Dietas gordas; Síndrome metabólica; Transgenerational epigenetic inheritance; Metabolic syndrome ; Lipidómica; Childhood obesity; Reversão da dieta; Mitochondrial physiology; Metabolic syndrome ; DESeq2; R; Linux; sncRNA; Análise Multivariada; Metabolismo; Fisiologia mitocondrial; Esteatose; Ciências da Reprodução; mixOmics; RNAseq analysis; sc & snRNAseq pipelines; Epigenetics; Proteomics; Transcriptomics; Biochemistry; Obesity; Male fertility; Immunology; Flow cytometry; metabolic assays; Seahorse; antioxidant mechanisms; Metabolic profiling; Enzymatic activity quantification; macrophage; monocyte; innate immunology; ontogeny; steady-state; tissue-resident macrophage; .
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Identification

Personal identification

Full name
LUIS DANIEL MACHADO CRISÓSTOMO

Citation names

  • Crisóstomo, Luís

Author identifiers

Ciência ID
B81B-CA37-E6D7
ORCID iD
0000-0002-9563-6364
Google Scholar ID
L5IfRskAAAAJ
Scopus Author Id
56781569200

Email addresses

  • luis.crisostomo@utu.fi (Professional)

Telephones

Mobile phone
  • (+358) 451592412 (Personal)

Addresses

  • Medicity Research lab, Tykistökatu 6, 20720, Turku, Turku, Finland (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences
  • Natural sciences - Biological Sciences
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Basic Medicine
  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Elementary (A2) Upper intermediate (B2) Intermediate (B1) Intermediate (B1) Beginner (A1)
Spanish; Castilian Elementary (A2) Intermediate (B1) Intermediate (B1) Intermediate (B1) Elementary (A2)
Education
Degree Classification
2017/10 - 2022/03
Concluded
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
"Paternally induced transgenerational effects of high fat diets" (THESIS/DISSERTATION)
2020/11/11 - 2021/08/19
Concluded
 Nature Masterclass - Effective collaboration in Research (Graduado)
Springer Nature, Luxembourg
2020/04/12 - 2020/04/15
Concluded
 Scientific Writing and Communication Seminar (Graduado)
Universitetet i Bergen, Norway
2019/05/06 - 2019/05/24
Concluded
 Laboratory Animal Science Course - FELASA C (Outros)
Major in Functions A, B and D - Mouse, rat, fish and zebra-fish
Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
 Approved
2019/03/01 - 2019/05/13
Concluded
 Practical Peer-Review course (Graduado)
Publons Academy, New Zealand
 Approved
2013/10 - 2014/09
Concluded
 Biomedicina (Curso de doutoramento (conclusão de unidades curriculares))
Universidade da Beira Interior Faculdade de Ciencias da Saude, Portugal
 15
2011/09/22 - 2013/07/23
Concluded
 Ciências Biomédicas (Mestrado)
Universidade da Beira Interior Faculdade de Ciencias da Saude, Portugal
"Pilot-Model for oxidative post-competition recovery in swimmers" (THESIS/DISSERTATION)
 17
2008/09/22 - 2011/07/08
Concluded
 Ciências Biomédicas (Licenciatura)
Universidade da Beira Interior Faculdade de Ciencias da Saude, Portugal
"Gene manipulation towards a perfect Man" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2022/07/11 - Current Postdoc (Research) Turun yliopisto lääketieteellinen tiedekunta, Finland
MediCity Research Laboratory, Finland
2016/09/05 - 2022/12/31 Researcher (Research) Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal
2021/07/01 - 2022/06/30 Researcher (Research) Turun yliopisto Biolääketieteen laitos, Finland
Turun yliopisto Integratiivinen fysiologia ja farmakologia, Finland
2020/01/02 - 2020/06/30 Visiting Researcher (Research) Turun yliopisto Integratiivinen fysiologia ja farmakologia, Finland
Turun yliopisto Integratiivinen fysiologia ja farmakologia, Finland
2017/02/06 - 2020/02/06 Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
2017/02/06 - 2020/02/01 Researcher (Research) Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
2011/01/04 - 2016/09/02 Researcher (Research) Centro de Investigacao em Desporto Saude e Desenvolvimento Humano, Portugal
2012/06/23 - 2013/10/31 Research Trainee (Research) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2012/06/23 - 2013/10/31 Research Trainee (Research) Universidade da Beira Interior Faculdade de Ciencias da Saude, Portugal

Positions / Appointments

Category
Host institution 		Employer
2012/01 - 2013/12 Conselheiro Pedagógico Universidade da Beira Interior Faculdade de Ciencias da Saude, Portugal

Others

Category
Host institution 		Employer
2014/06/16 - 2016/09/02 Consultor de Informática Accenture Technical Solutions, S.A., Portugal
Projects

Grant

Designation Funders
2017/09/01 - 2021/08/31 Paternally induced transgenerational effects of high fat diets
SFRH/BD/128584/2017
PhD Student Fellow
Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal

Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
Fundacao para a Ciencia e a Tecnologia
Ongoing
2017/03 - 2018/03 Biomarcadores transgeracionais da Diabetes Mellitus tipo 2: ficção ou necessidade de ação?
Bolsa Nuno Castel Branco
Master Student Fellow
Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal

Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal
Sociedade Portuguesa de Diabetologia
Concluded
2007 - 2013 Laboratório de Investigação em Desporto e Saúde
ALENT-07-0262-FEDER-001883
 Universidade de Coimbra

Contract

Designation Funders
2018/07/26 - 2021/01/21 TRaitor - Tracking TRAnsgenerational epigenetic Inheritance of metabolic diseases Transmitted via overweight or obese fathers
PTDC/MEC-AND/28691/2017
PhD Student Fellow
Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal
 Fundacao para a Ciencia e a Tecnologia
Ongoing
2019/03 - 2020/03 Paternal glucose metabolism deregulation and diabetes predisposition
GIFT Project Grants 2019
Researcher
Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal

Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
Sociedade Portuguesa de Diabetologia
Concluded
2015 - 2020 Aquaporins as molecular partners of CFTR in the Blood-Testis Barrier: a crossroad between human male infertility and cystic fibrosis?
FCT - PTDC/BBB-BQB/1368/2014
Researcher
Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal

Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
Fundacao para a Ciencia e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Crisóstomo, Luís; Parena, Ae; Hyseni, Besmir; Bergman, Hans; Mildner, Alexander. Corresponding author: Mildner, Alexander. "Homeostatic Functions of Tissue-Resident Macrophages and Their Role in Tissue Maintenance". In Monocytes and Macrophages in Development, Regeneration, and Disease, edited by Malgorzata Kloc; Jacek Z. Kubiak; Marta Halasa, 3-54. Springer Nature Switzerland, 2024.
    Published • 10.1007/978-3-031-65944-7_1
  2. Crisóstomo, Luís; Alves MG; Gorga A; Sousa M; Riera MF; Galardo MN; Meroni SB; Oliveira, Pedro F.. Corresponding author: Meroni SB. "Molecular Mechanisms and Signaling Pathways Involved in the Nutritional Support of Spermatogenesis by Sertoli Cells.". In Methods in molecular biology (Clifton, N.J.), edited by Alves MG; Oliveira, Pedro F.. New York, United States: Humana Press, 2018.
    Published • 10.1007/978-1-4939-7698-0_11
Conference abstract
  1. Crisóstomo, Luís; Rato, Luis; Videira, Romeu; Jarak, Ivana; Starcevic, Kristina; Masek, Tomislav; JOAO FILIPE RAPOSO; Oliveira, Pedro F.; Alves, Marco G.. "Diet intervention after childhood obesity is insufficient to revert changes in testicular metabolic/lipidomic profiles and sperm quality". Paper presented in 45th FEBS Congress, Ljubljana, 2020.
    Accepted
  2. Alves, Marco G.; Crisóstomo, Luís; Videira, Romeu; Rato, Luis; Jarak, Ivana; JOAO FILIPE RAPOSO; Oliveira, Pedro F.. "A pré-diabetes associada à síndrome metabólica induzida por uma dieta rica em gordura promove alterações no metabolismo testicular dos descendentes". Paper presented in 16º Congresso Português de Diabetes, Vilamoura, 2020.
    Published
  3. Alves, Marco G.; Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.. "Uma dieta rica em gordura altera o metabolismo testicular o que compromete a qualidade reprodutiva". Paper presented in 15º Congresso Português de Diabetes, Vilamoura, 2019.
    Accepted
  4. Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.; Alves, Marco G.. "Reversão da dieta rica em gordura para uma dieta normal, no início da idade adulta, previne a síndrome metabólica mas não melhora a qualidade espermática". Paper presented in 15º Congresso Português de Diabetes, Vilamoura, 2019.
    Published
Conference poster
  1. Agualusa, Nair; Carrageta, David F; Pereira, Sara C; Barros, Alberto; Crisóstomo, Luís; Álves, Marco G; Oliveira, Pedro F. "Insulin-like growth factors: possible players regarding male fertility". Paper presented in 25th European Congress of Endocrinology, 2023.
  2. Pereira, Sara C; Freire-Brito, Lais; Guerra-Carvalho, Bárbara; Carrageta, David F; Bernardino, Raquel L; Crisóstomo, Luís; Terzo, S; et al. "High-fat diet promotes 3¿mt-tiRNA-Met epididymosome enrichment which correlates to lower spermatozoa mitochondrial translation". Paper presented in 25th European Congress of Endocrinology, 2023.
  3. Pereira, Sara C; Freire-Brito, Laís; Guerra-Carvalho, Bárbara; Carrageta, David F; Bernardino, Raquel L; Crisóstomo, Luís; Terzo, S; et al. "Epididymosome 3¿mt-tiRNA-Met responds to high-fat diet and is negatively correlated with sperm quality". Paper presented in 57th Annual Scientific Meeting of the European Society for Clinical Investigation, 2023.
  4. Crisóstomo, Luís; Bourgery, Matthieu; Rato, Luis (A914-6344-CD2D); RAPOSO, JOAO; Kotaja, Noora; Oliveira, Pedro F.; Alves, Marco G.. "Testicular “inherited metabolic memory” of ancestral high-fat diet depends on sperm sncRNA content". Paper presented in EMBL symposium The non-coding genome, 2021.
  5. Crisóstomo, Luís; Videira, Romeu; Jarak, Ivana; Starcevic, Kristina; Masek, Tomislav; Rato, Luis (A914-6344-CD2D); RAPOSO, JOAO; Oliveira, Pedro F.; Alves, Marco G.. "Testicular "Inherited metabolic memory" of high-fat diet causes sperm defects up to grandsons". Paper presented in WebRePRO, 2021.
  6. Crisóstomo, Luís; Rato, Luis (A914-6344-CD2D); Jarak, Ivana; Videira, Romeu; Starcevic, Kristina; Masek, Tomislav; JOAO FILIPE RAPOSO; et al. "Ancestral paternal exposure to high-fat diets causes testicular metabolic and functional disturbances in mice up to two generations". Paper presented in 45th FEBS Congress, 2021.
  7. Alves, Marco G.; Crisóstomo, Luís; Videira, Romeu; Rato, Luis; Jarak, Ivana; JOAO FILIPE RAPOSO; Oliveira, Pedro F.. "A diabetes tipo 2 associada ao síndrome metabólico induzido por uma dieta rica em gordura promove alterações no metabolismo testicular dos descendentes". Paper presented in 16º Congresso Português de Diabetes, 2020.
  8. Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Videira, Romeu; Starcevic, Kristina; Masek, Tomislav; Silva, Branca M; et al. "Can a diet intervention in young mice fed with high fat diet lead to better sperm quality?". Paper presented in 2º Meeting do 3º Ciclo em Ciências Biomédicas, 2019.
  9. Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.; Alves, Marco G.. "Paternal inheritance of metabolic syndrome traits and sperm anomalies induced by high-fat diet in mice". Paper presented in Epigenetic Inheritance Symposium, 2019.
  10. Alves, Marco G.; Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.. "Uma dieta rica em gordura altera o metabolismo testicular o que compromete a qualidade reprodutiva". Paper presented in 15º Congresso Português de Diabetes, 2019.
  11. Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.; Alves, Marco G.. "Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility?". Paper presented in 11th MitoEAGLE Training School - MiPschool 2018, 2018.
  12. Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.; Alves, Marco G.. "Diet reversion prevents the onset of a pre-diabetic state in mice, but not male reproductive dysfunction". Paper presented in International Congress of Diabetes & Metabolism, 2018.
  13. Crisóstomo, Luís; Rato, Luis; Jarak, Ivana; Silva, Branca M; JOAO FILIPE RAPOSO; Oliveira, Pedro F.; Alves, Marco G.. "Can weight loss revert the damage induced by obesity in male fertility?". Paper presented in I NoTeS Congress, 2018.
  14. Crisóstomo, Luís; Jarak, Ivana; Carvalho, Rui; Sousa, Mário; Barros, Alberto; Alves, Marco G.; Oliveira, Pedro F.. "Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential". 2017.
Journal article
  1. Kristiina Makkonen; Meeri Jännäri; Crisóstomo, Luís; Matilda Kuusi; Konrad Patyra; Vladyslav Melnyk; Veli Linnossuo; et al. Corresponding author: Jukka Kero. "Mechanisms of thyrotropin receptor-mediated phenotype variability deciphered by gene mutations and M453T knock-in model". JCI Insight (2024): https://doi.org/10.1172/jci.insight.167092.
    In press
  2. Soraia Pinto; Bárbara Guerra-Carvalho; Luís Crisóstomo; António Rocha; Alberto Barros; Marco G. Alves; Pedro F. Oliveira. "Metabolomics Integration in Assisted Reproductive Technologies for Enhanced Embryo Selection beyond Morphokinetic Analysis". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms25010491.
    Published • 10.3390/ijms25010491
  3. Agarwal, Ashok; Cannarella, Rossella; Saleh, Ramadan; Boitrelle, Florence; Gül, Murat; Toprak, Tuncay; Salvio, Gianmaria; et al. Corresponding author: Agarwal, Ashok. "Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis". The World Journal of Men's Health 41 2 (2023): 289. http://dx.doi.org/10.5534/wjmh.220142.
    10.5534/wjmh.220142
  4. Luís Crisóstomo; Pedro F. Oliveira; Marco G. Alves. "Antioxidants, Oxidative Stress, and Non-Communicable Diseases". Antioxidants 11 6 (2022): 1080-1080. https://doi.org/10.3390/antiox11061080.
    10.3390/antiox11061080
  5. Crisóstomo, Luís; Matthieu Bourgery; Luís Pedro Rato; João F. Raposo; R.L.Batterham; Noora Kotaja; Alves, Marco G.. Corresponding author: Alves, Marco G.. "Testicular "Inherited Metabolic Memory" of Ancestral High-Fat Diet Is Associated with Sperm sncRNA Content". Biomedicines (2022): https://www.mdpi.com/2227-9059/10/4/909.
    Open access • Published • 10.3390/biomedicines10040909
  6. Luís Crisóstomo; Romeu A. Videira; Ivana Jarak; Kristina Starcevic; Tomislav Mašek; Luís Rato; João F. Raposo; et al. "Inherited Metabolic Memory of High-Fat Diet Impairs Testicular Fatty Acid Content and Sperm Parameters". Molecular Nutrition & Food Research (2022): 2100680-2100680. https://doi.org/10.1002/mnfr.202100680.
    10.1002/mnfr.202100680
  7. Ashok Agarwal; Renata Finelli; Damayanthi Durairajanayagam; Kristian Leisegang; Ralf Henkel; Gianmaria Salvio; Azin Aghamajidi; et al. "Comprehensive Analysis of Global Research on Human Varicocele: A Scientometric Approach". The World Journal of Men's Health (2022): https://doi.org/10.5534/wjmh.210202.
    10.5534/wjmh.210202
  8. Crisostomo L; Jarak I; Rato LP; Raposo JF; Batterham RL; Oliveira PF; Alves MG. "Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in mice". 11 (2021): https://www.nature.com/articles/s41598-021-88981-3.pdf?origin=ppub.
    10.1038/s41598-021-88981-3
  9. Crisostomo, Luis; Oliveira, Pedro F; Alves, Marco G; Luís Crisóstomo; Pedro F. Oliveira; Marco G. Alves. "Sperm, metabolic memory, and echoes from Lamarck". European Journal of Clinical Investigation (2021): https://publons.com/publon/35702805/.
    10.1111/ECI.13492
  10. Bárbara Guerra-Carvalho; David F. Carrageta; Luís Crisóstomo; Rui A. Carvalho; Marco G. Alves; Pedro F. Oliveira. "Molecular mechanisms regulating spermatogenesis in vertebrates: Environmental, metabolic, and epigenetic factor effects". Animal Reproduction Science (2021): https://publons.com/wos-op/publon/50521594/.
    10.1016/J.ANIREPROSCI.2021.106896
  11. Crisóstomo L; Pereira SC; Monteiro MP; Raposo JF; Oliveira PF; Alves MG; Crisostomo, Luis; et al. "Lifestyle, metabolic disorders and male hypogonadism - A one-way ticket?". Molecular and cellular endocrinology (2020): http://europepmc.org/abstract/med/32707080.
    10.1016/j.mce.2020.110945
  12. Sara C Pereira; Luís Crisóstomo; Mário Sousa; Pedro F Oliveira; Marco G Alves; Caroline Burson; Pereir, Sara C.; et al. "Metabolic diseases affect male reproduction and induce signatures in gametes that may compromise the offspring health". Environmental Epigenetics (2020): https://doi.org/10.1093/eep/dvaa019.
    10.1093/eep/dvaa019
  13. Crisostomo, Luis; Videira, Romeu A; Jarak, Ivana; Starcevic, Kristina; Masek, Tomislav; Rato, Luis; Raposo, Joao F; et al. "Diet during early life defines testicular lipid content and sperm quality in adulthood". American Journal of Physiology-Endocrinology and Metabolism (2020): https://publons.com/publon/35539412/.
    10.1152/AJPENDO.00235.2020
  14. Crisostomo, L.; Rato, L.; Jarak, I.; Videira, R.; Starcevic, K.; Masek, T.; Raposo, J.; Pedro, O.; Alves, M. G.. "Permanent testicular metabolomic and lipidomic signatures induced by the adoption of a high-fat diet in childhood and sperm quality in adulthood". Human Reproduction (2020): https://publons.com/publon/35539382/.
  15. Erich Gnaiger; Eleonor Aasander Frostner; Norwahidah Abdul Karim; Engy Ali Abdel-Rahman; Nada A Abumrad; Dario Acuna-Castroviejo; Reginald C Adiele; et al. "Mitochondrial physiology". (2020): https://publons.com/wos-op/publon/32435926/.
    10.26124/BEC:2020-0001.V1
  16. Crisóstomo, Luís; Crisostomo, Luis; Rato, Luis; Jarak, Ivana; Silva, Branca M.; Raposo, Joao F.; Batterham, Rachel L.; Oliveira, Pedro F.; Alves, Marco G.. "A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome". Reproduction (2019): http://dx.doi.org/10.1530/rep-19-0259.
    10.1530/rep-19-0259
  17. Crisóstomo, Luís; Boussada, Marwa; Dias, Tania R.; Crisostomo, Luis; Akacha, Azaiez B.; Ali, Ridha B.; El May, Michele V.; Alves, Marco G.; Oliveira, Pedro F.. "A new thiocyanoacetamide (2-cyano-2-p-nitrophenyl-Nbenzylthioamide) reduces Doxorubicin-induced in vitro toxicity in Sertoli cells by decreasing apoptosis and autophagy". Theriogenology (2019): http://dx.doi.org/10.1016/j.theriogenology.2019.08.030.
    10.1016/j.theriogenology.2019.08.030
  18. Crisostomo, L.; Rato, L.; Jarak, I.; Silva, B. M.; Raposo, J. F.; Oliveira, P. F.; Alves, M. G.; et al. "High-fat diet compromises male fertility that is not surpassed by reversion to a controlled diet". FEBS Open Bio (2018): https://publons.com/publon/10779205/.
  19. Oliveira, Pedro F.; Crisóstomo, Luís; Sousa, Mário; Monteiro, Mariana P.; Macedo, Maria; JOAO FILIPE RAPOSO; Alves, Marco G.. "O papel do Espermatozoide na Transmissão à Descendência do Risco para Diabetes Mellitus". Revista Portuguesa de Diabetes 12 4 (2017): 149-158. http://www.revportdiabetes.com/wp-content/uploads/2018/02/RPD-Vol-12-n%C2%BA-4-Dezembro-2017-Artigo-Revis%C3%A3o-p%C3%A1g-149-158.pdf.pdf.
    Open access • Published
  20. Luís Crisóstomo; Marco G Alves; Giuseppe Calamita; Mário Sousa; Pedro F Oliveira. "Glycerol and testicular activity: the good, the bad and the ugly". MHR: Basic science of reproductive medicine 23 11 (2017): 725-737. https://doi.org/10.1093/molehr/gax049.
    10.1093/molehr/gax049
  21. Crisóstomo, Luís; Luís Daniel Machado Crisóstomo; Sousa M; Alves MG; Oliveira PF. "The Burden of Metabolic Diseases on Male Reproductive Health". International Journal of Diabetology & Vascular Disease Research (2017): http://scidoc.org/IJDVR-2328-353X-05-001e.php.
    10.19070/2328-353X-1700012E
  22. Costa, A.M.; Grazina, C.; Miragaia, D.; Crisóstomo, L.; de Carvalho Pedro, G.; Costa, Aldo; Grazina, Cide; et al. "Contexto de desenvolvimento desportivo em clubes de natação: Um estudo preliminar sobre as perceções dos nadadores portugueses | Sports development environment in swimming clubs: A preliminary study on portuguese swimmers' perceptions". Revista Iberoamericana de Psicologia del Ejercicio y el Deporte 12 2 (2017): 231-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020233697&partnerID=MN8TOARS.
    Published
  23. Costa, Aldo M.; Grazina, Cide; Miragaia, Dina; Crisostomo, Luis; de Carvalho, Pedro G.; Costa AM; Grazina C; et al. "SPORTS DEVELOPMENT ENVIRONMENT IN SWIMMING CLUBS: A PRELIMINARY STUDY ON PORTUGUESE SWIMMERS' PERCEPTIONS". Revista Iberoamericana de Psicologia del Ejercicio Y el Deporte 12 (2017): 231-236. https://publons.com/publon/27439978/.
  24. Monteiro, J. P.; Jesus, T. T.; Crisostomo, L.; Sousa, M.; Barros, A.; Oliveira, P. F.; Alves, M. G.. "mTOR coordinates the response to available energy substrates in human Sertoli cells: A defining point for male fertility?". The FEBS Journal (2017): https://publons.com/publon/6295754/.
  25. Casanova N; Palmeira-De-Oliveira A; Pereira A; Crisostomo L; Travassos B; Costa AM; Casanova, N.; et al. "Cortisol, testosterone and mood state variation during an official female football competition". Journal of Sports Medicine and Physical Fitness 56 6 (2016): 775-781. https://www.minervamedica.it/en/journals/sports-med-physical-fitness/article.php?cod=R40Y2016N06A0775.
    Published • 10.1111/febs.14171
Thesis / Dissertation
  1. Crisóstomo, Luís Daniel Machado. "Pilot-model for oxidative post-competition recovery in swimmers". Master, Universidade da Beira Interior Faculdade de Ciencias da Saude, 2013. http://hdl.handle.net/10400.6/1340.

Other

Other output
  1. Permanent testicular metabolomic and lipidomic signatures induced by the adoption of a high-fat diet in childhood and sperm quality in adulthood. 2020. https://academic.oup.com/humrep/article/35/Supplement_1/i1/5867890.
    10.1093/humrep/35.Supplement_1.1
  2. High-fat diet compromises male fertility that is not surpassed by reversion to a controlled diet. 2018. https://febs.onlinelibrary.wiley.com/toc/22115463/2018/8/S1.
    10.1002/2211-5463.12453
  3. mTOR coordinates the response to available energy substrates in human Sertoli cells: A defining point for male fertility?. 2017. https://febs.onlinelibrary.wiley.com/toc/17424658/2017/284/S1.
    https://doi.org/10.1111/febs.14174
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/11/04 Sperm small RNAs modulate testicular "inherited metabolic memory" of ancestral high-fat diet in mice Endopäivat – The Finnish Endocrinology Society Symposium
The Finnish Endocrinology Society (Helsínquia, Finland)
2019/10/14 “Mitogheist” – Is testicular mitochondrial dysfunction a ghost pattern of paternal high-fat diet in mice? MiP Conference MitoEAGLE 2019
COST Action MitoEAGLE; Faculty of Medicine of the University of Belgrade (Belgrado, Serbia)
2019/03/08 Reversão da dieta rica em gordura para uma dieta normal, no início da idade adulta, previne a síndrome metabólica mas não melhora a qualidade espermática 15º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia (Vilamoura, Portugal)
2018/10/23 Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility? 11th MitoEAGLE Training School - MiPschool 2018
COST Action MitoEAGLE; The Arctic University of Norway (Tromsø e Bergen, Norway)
2018/06/23 Can weight loss revert the damage induced by obesity in male fertility? I NoTeS Congress - Novel Therapeutic Strategies for Non-Communicable Diseases
Faculdade de Medicina Universidade do Porto (Porto, Portugal)
2018/05/07 Weight increase causes permanent damage on mice male fertility I Meeting PhD in Biomedical Sciences
Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2018/04/21 Obesidade e Diabetes - Da Prática Clínica à Investigação Básica Ciclo de Palestras "Amigos das Letras"
Associação "Amigos das Letras"; Biblioteca Municipal de Alcobaça (Alcobaça, Portugal)
2018/02/02 Obesidade e Diabetes - As epidemias silenciosas do Séc. XXI Colóquio do Rotary Club da Benedita
Rotary Club da Benedita (Benedita, Portugal)
2017/11/17 Glycerol metabolism and mitochondrial function in human Sertoli cells - a preliminary study MiP Conference MitoEAGLE 2017
Univerzita Karlova - Lékarská fakulta v Hradci Kralové (Hradec Kralové, Czech Republic)
2017/11/09 Glycerol and male reproductive (dys)function – an underestimated threat? i3S Annual Meeting
Instituto de Investigação e Inovação em Ciências da Saúde (Póvoa do Varzim, Portugal)
2017/10/27 Glycerol and testicular activity: the good, the bad and the ugly 3º Ciclo de Seminários Científicos UMIB
Unidade Multidisciplinar de Investigação Biomédica (UMIB-ICBAS) (Porto, Portugal)
2017/07/29 Glycerol metabolism in testicular cells - A mitochondrial tale that may control male reproductive potential 10th MiPschool & MITOEAGLE Workshop
COST Action CA15203 MitoEAGLE; University Center Obergurgl (Obergurgl, Austria)
2014/05/02 Pilot-model for oxidative post-competition recovery in swimmers Congresso em Ciências do Desporto, Exercício e Saúde
Departamento de Desporto, Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2013/04/29 Expressão de antioxidantes endógenos ao longo de uma Época Desportiva XXXVI Congresso Técnico-Científico APTN
Associação Portuguesa de Técnicos de Natação (Guimarães, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/09 - 2023/12/11 Abundância de mRNA de IGFs nos espermatozoides humanos e a sua associação com os resultados de técnicas de reprodução assistida
Co-supervisor of Nair Canoso Vicente Agualusa
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2021/12/01 - 2022/09/09 Testicular “Inherited metabolic memory” of ancestral exposure to high-fat diets is encoded by sperm RNAs
Co-supervisor of Ana Beatriz Teixaira Correia de Matos
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2020/12/01 - 2021/07/23 Mitochondria and antioxidants: the silent toll of childhood obesity to hepatic function
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/07/26 - 2021/07/31 WebRePRO - I Reproductive Sciences & Fertility Virtual Summit (2021/01/01 - 2021/07/27)
Congress (Member of the Organising Committee)
 Universidade de Aveiro, Portugal

Universidade do Porto, Portugal

Universidade do Minho, Portugal
2018/01 - 2018/07 I NoTeS Congress - Novel Therapeutic Strategies for Noncommunicable Diseases (2018/06/22 - 2018/06/23)
Congress (Member of the Organising Committee)
 Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal

Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal

Universidade do Porto Unidade de Investigacao e Desenvolvimento Cardiovascular, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Faculdade de Desporto, Portugal

Universidade de Tras-os-Montes e Alto Douro Centro de Investigacao e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade de Aveiro Unidade de Investigacao de Quimica Organica Produtos Naturais e Agroalimentares, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
2010/03/22 - 2011/03/22 II Jornadas Nacionais de Ciências Biomédicas (2011/03/03 - 2011/03/05)
Conference (President of the Organising Committee)
 BioMedUBI - Núcleo de Estudantes de Ciências Biomédicas da Universidade da Beira Interior, Portugal

Universidade da Beira Interior Faculdade de Ciencias da Saude, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/12/19 Dieta Rica em Gordura num Modelo Transgeracional: Genes Associados à Obesidade e Stress Oxidativo em Vesículas Seminais de Ratinho
(Thesis) Main arguer
 Beatriz Gonzalez Rodrigues (Master)
Universidade de Aveiro, Portugal
2021/07/23 Mitochondria and antioxidants: the silent toll of childhood obesity to hepatic function
Supervisor
 Bárbara Soares Ferreira (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Conference scientific committee

Conference name Conference host
2021/07/23 - 2021/07/25 XI International Natural Sciences Tournament (INST) Online
2020/02/07 - 2020/02/12 X International Natural Sciences Tournament (INST) Centro de Ciências Biológico-Químicas da Universidade de Varsóvia, Varsóvia, Polónia
2019/02/01 - 2019/02/06 IX International Natural Sciences Tournament (INST) Tallinn University of Technology

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/11/02 - 2021/11/30 Métodos moleculares Metabolismo - Biopatologia e Experimentação (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2021/01/01 - 2021/01/31 Métodos moleculares Metabolismo - Biopatologia e Experimentação (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2021/11 - Current PLoS One (1932-6203) Public Library of Science
2021/10 - Current Frontiers in Cell and Developmental Biology (2296-634X) Frontiers Media S.A.
2021/09 - Current Environmental International (0160-4120) Elsevier
2021/01 - Current Reproductive Biology (1642-431X) Elsevier
2021/01 - Current Reproductive Sciences (1933-7205) Springer Nature
2020/01 - Current Clinical Epidemiology (1179-1349) Dove Medical Press
2020/01 - Current Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy (1178-7007) Dove Medical Press
2020/01 - Current International Journal of General Medicine (1178-7074) Dove Medical Press
Distinctions

Award

2022 Best pitch talk - Endopäivät 2021
The Finnish Endocrine Society, Finland
2021 Honorable mention - Best poster presentation
WebRePRO Scientific Committee, Portugal
2021 Poster of the day - the 45th FEBS Virtual Congress
Federation of European Biochemical Societies, United Kingdom

FEBS Letters, United Kingdom
2019 Melhor Poster - 2º Meeting to 3º Ciclo em Ciências Biomédicas do ICBAS
Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
2018 Melhor apresentação de poster - Investigação Básica
Sociedade Portuguesa de Diabetologia, Portugal
2013 3º Prémio - Melhor comunicação livre na categoria de Treino
Associação Portuguesa de Técnicos de Natação, Portugal

Other distinction

2021 Conference Grant - virtual EMBO | EMBL Symposium: The Non-Coding Genome
European Molecular Biology Laboratory, Germany
2020 YSF & FEBS Congress Grant
Federation of European Biochemical Societies, United Kingdom
2019 EFSD Albert Renold Travelling Grant
European Foundation for the Study of Diabetes, Germany
2019 Congress Grant MitoEAGLE
COST Action MitoEAGLE, Austria
2018 MiPschool 2017 MITOEAGLE Scholarship
COST Action MitoEAGLE, Austria
2018 ICDM Travelling Grant
Korean Diabetes Association, South Korea
2017 MiPschool 2017 MITOEAGLE and MITOEAGLE workshop Extended Scholarship
COST Action MitoEAGLE, Austria
2017 MiP conference 2017 Hradec Králové - ITC Conference Grant
COST Action MitoEAGLE, Austria
2017 Bolsa Individual de Doutoramento FCT
Fundacao para a Ciencia e a Tecnologia, Portugal