Degree in Chemical Engineering from the Polytechnic Institute of Viana do Castelo. Master's degree in Medicinal Chemistry from the University of Minho. PhD in Chemistry from the University of Évora. Synthesis of compounds with potential anti-tumor and / or anti-angiogenic activities (eg thienopyridines, thienopyrimidines, thienopyrazines, thienoquinolines, thienoquinoxalines ...); Synthesis of compounds with potential Alzheimer's and / or Parkinson's activity (eg Isoquinolinones, Azepinones, Dibenzodiazepines, Acridines ...); Mechanistic studies for the formation of different compounds using NHO; New heterocyclic compounds for dual activity, anti-tumoral and anti-multidrug resistence Characterization of the compounds by NMR spectrometry, including heteronuclear homo and bidimensional correlations, COZY, HSQC and HMBC. Analysis of purity of the compounds by HPLC; Development of a new generation of hydrogels based on natural polymers combined with catechol groups, in particular hyaluronic acid and chitosan that have demonstrated adequate properties such as biocompatibility for several biomedical applications; Characterization of the modification of the natural polymers and hydrogel by chemical and physical properties: FTIR, NMR, GPC, SEM coupled with EDS, AFM, micro-CT, rheology, swelling and compressive experiments and bioactivity studies.