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Ana Gonçalves Domingos is a coordinator investigator at the Medical Parasitology Unit, at the Institute of Hygiene and Tropical Medicine, NOVA University of Lisboa (IHMT/UNL). She has a PhD in Biology by University of Lisbon (1997) and obtained the Habilitation degree in Biomedical Sciences – Parasitology, at UNL (2011). She was invited professor at the University of Lurio, Mozambique (2014-2017). Ana Domingos teaches in the Medical Parasitology and Biomedical Sciences Master courses being the coordinator of two curricular Units, at IHMT/UNL, and in other Master Courses in countries such as Mozambique and Angola. In parallel, she is also participating or participated in several in PhD Courses namely Biomedical Sciences, Genetic of Human Diseases, Tropical Knowledge and Management at UNL and GABBA-PhD Course at the University of Oporto. She takes part, as organizer and teacher, in short courses held in Portuguese speaking countries as Mozambique and Cape Verde. Last 5 years, Ana Domingos supervised several Post-Doc Fellows, PhD students, and MSc students and many grant holders. Her research interest is focused in improving knowledge on parasite and vectors interaction. Research activities rely on a system biology approach, under funded projects, using methodologies such as proteomics, transcriptomics and functional genomics and immunoinformatic. Such methodologies allowed the identification of vaccine candidates and drug targets in both parasites and vectors of diseases having a great human health and animal production impact such as malaria, babesiosis and theileriosis. Her team recently achieved and analyzed the transcriptome and proteome of different arthropods and tested newly identified antigens on vaccination trials. Last 10 years she developed 12 funded projects (6, as Principal investigator) and published 30 peer-reviewed scientific papers. Currently she belongs to the editorial board of four journals such as the “Scientific Journals” and “Frontiers” and was recently the national representant of two Cyted networkings being from the scientific committee of the Cyted InCoCarr. She is also participating in two COST Actions. She is member of the Scientific Commission of the “In Vivo Arthropod Security Facility (VIASEF)”, IHMT/UNL, since 2021. She is takes part of the International Scientific Committee of the congress on “Tick and Tick-borne Pathogens – TTP11” that will be held in August, 2024 Since 2022, she member of the General Council of the University Nova of Lisbon.
Identification

Personal identification

Full name
Ana Isabel Amaro Gonçalves Domingos

Citation names

  • Domingos, Ana
  • Ana Gonçalves Domingos

Author identifiers

Ciência ID
B917-8F1A-9C57
ORCID iD
0000-0002-4570-2060
Researcher Id
I-8409-2012
Scopus Author Id
7003637537

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Parasitology

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Intermediate (B1) Upper intermediate (B2) Advanced (C1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Intermediate (B1) Beginner (A1)
Portuguese (Mother tongue)
Spanish; Castilian Elementary (A2) Intermediate (B1) Beginner (A1) Elementary (A2) Elementary (A2)
Education
Degree Classification
2011 - 2011
Concluded
Ana Isabel Amaro Gonçalves Domingos (Título de Agregado)
Major in Biomedical Sciences - Parasitology
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"Curricular unit: "Molecular biology tools applied to Babesiose study" Seminar: "Gene functional analyses for the development of vaccines against ticks and tick-transmitted diseases"" (THESIS/DISSERTATION)
unanimity
1997/10/20
Concluded
Biologia (Doutoramento)
Major in Especialidade: Biotecnologia Vegetal
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
"An Aspartic Proteinase from Flowers of Centaurea Calcitrapa: Purification, Molecular Cloning and Modelling of Its Three-dimensional Struture" (THESIS/DISSERTATION)
unanimity
Affiliation

Science

Category
Host institution
Employer
2010 - Current Coordinating Researcher (Research) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projects

Grant

Designation Funders
2007/10 - 2012/08 Protein-disulfide isomerase as a target for besnoitiosis therapy. Molecular characterization and studies of its role in infection and host immune response
PTDC/CVT/65674/2006
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Instituto de Investigação Científica Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade de Évora, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluded
2006/08 - 2009/09 Biochemical characterization and inhibition studies of recombinant cysteine proteases of Plasmodium chabaudi, an animal model for human malaria.
Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
1995/01/01 - 1995/12/31 PROTEASES COM ACTIVIDADE COAGULANTE DO LEITE DE CENTAUREA CALCITRAPA - PURIFICAÇÃO E CARACTERIZAÇÃO
PRAXIS XXI/BD/3796/94
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2024/02 - 2026/01 Indicadores de resistência ao carrapato Rhipicephalus microplus e às babesiose em bovinos da raça Canchim: novas estratégias
Fapesp 2022/16262-3
Fapesp 2022/16262-3
Research Fellow
Fundação de Amparo à Pesquisa do Estado de São Paulo
Ongoing
2021/01/01 - 2025/12/31 Translation and Innovation towards Global Health
LA/P/0117/2020
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade de Lisboa Faculdade de Medicina Dentária, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/12 - 2024/09/11 A toolbox to decipher the cross-talk between Babesia ovis and the host cell
2022.03176.PTDC
Researcher
Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/09/01 - 2022/09/30 The Ixodes ricinus group of ticks in the western Mediterranean region and north Africa: new insights in to their population genetics and microbiome fauna.
PTDC/SAU-PAR/28947/2017
Researcher
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/04 - 2022/04/03 TICKOMIC: Exploring the tick-host interactome: on the path to vaccine development.
PTDC/CVT-CVT/29073/2017
Universidade Nova de Lisboa, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/02/07 - 2021/02/06 Influência da imunidade da carraça na competência vetorial e atividade anti-parasitária”,
42295NE
Principal investigator
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Global Health and Tropical Medicine
UID/Multi/04413/2019
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/06/01 - 2019/08/31 TickVac: A proteomic and functional genomic insight into the Rhipicephalus sanguineus-Ehrlichia canis interactome towards disease control.
PTDC/CVT-WEL/1807/2014
Principal investigator
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Instituto de Investigación en Recursos Cinegéticos, Spain

Universidade Estadual Paulista Júlio de Mesquita Filho, Brazil
Fundação para a Ciência e a Tecnologia
Concluded
2013/07/01 - 2015/12/31 Functional genomics of Rhipicephalus bursa and Babesia ovis interactions towards disease control.
PTDC/CVT-EPI/4339/2012
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Instituto de Investigación en Recursos Cinegéticos, Spain
Fundação para a Ciência e a Tecnologia
Concluded
2013/05/01 - 2015/12/31 Let´s make them fall: A genomic, proteomic and immuno-histologic approach on the involution of tick aggregation cement.
PTDC/CVT-EPI/3460/2012
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Instituto de Investigação Científica Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Instituto de Investigação Científica Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2014/06/30 Differential expression and functional characterization of tick (Rhipicephalus annulatus) genes in response to pathogen infection (Babesia bigemina).
PTDC/CVT/112050/2009
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Kimron Veterinary Institute, Israel

Instituto de Investigación en Recursos Cinegéticos, Spain
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010/03/01 - 2013/08/31 A challenge for the treatment of parasitic diseases: rational design of Trifluralin derivatives and appropriate nanoformulations
PTDC/CVT/098290/2008
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Laboratório Nacional de Energia e Geologia - Campus do Lumiar, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 18 - 2011-2012
PEst-OE/SAU/LA0018/2011
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/10/01 - 2011/09/30 Trypanosome brucei peptidase inhibitors. Immunolocalization, secretion and potential use as targets for therapy
PTDC/CVT/67086/2006
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2004 - 2006 Efeito da cloroquina na modulação da resposta do mosquito à infecção por Plasmodium spp.
POCTI/MGI/44905/2002
Research Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal

Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
1999 - 2000 Toward a rational design of mechanism-based irreversible protease inhibitors using the ¿-lactam motif.
PRAXIS/P/QUI/10039/1998
Co-Principal Investigator (Co-PI)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
1997 - 1998 MECASCI - Melhoramento do queijo Castelões por utilização de Ciprozinas para coagulação de leite de vaca
na
Co-Principal Investigator (Co-PI)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal

Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
Concluded
Outputs

Publications

Book
  1. Patrício, Catarina ; Antunes, Sandra. Recombinant protein production: A case study research report. 2015.
    Published
  2. Couto, Joana; Renato Silva-Pinheiro. Transcriptomic analysis of Anopheles stephensis salivary glands. Ed. Verlag: LAP - Lambert Academic Publishing. 2015.
    Published
  3. Lérias, Joana; Luís Madeira de Carvalho; Antunes, Sandra. Calreticulin from Rhipicephalus annulatus infected by Babesia bigemina. LAP - Lambert Academic Publishing. 2013.
    Published
Book chapter
  1. Antunes, Sandra; Margarita M. Villar-Rayo; de la Fuente, José. "Functional genomics of tick vectors challenged with the cattle parasite Babesia bigemina". In Molecular Diagnostics in Laboratory Veterinary Practice – Section IV: Integrative Omics and High-Throughput Platforms to Unravel the Biology of Pathogens and their Interaction with the host, edited by Springer, 475-489. Springer – Series “Methods in Molecular Biology, 2018.
    Published
  2. S Couri; Y Park; G Pastore. "Enzimas na produção de alimentos e bebidas". In Enzimas em Biotecnologia, produção, aplicações e mercado, 153-178. ISBN: 9788571931893, 2008.
    Published
  3. DOMINGOS, A; MIGUEL, G; CLEMENTE, A; PAIS, MS; VARDARSUKAN, F; SUKAN, SS. "PRODUCTION OF CLOTTING ENZYMES BY CENTAUREA-CALCITRAPA L (COMPOSITAE)". 511-512. 1992.
Book review
  1. de la Fuente, José; Antunes, Sandra; Bonnet, Sarah; Cabezas-Cruz, Alejandro; Domingos, Ana G.; Estrada-Peña, Agustín; Johnson, Nicholas; et al. "Tick-pathogen interactions and vector competence:". http://www.scopus.com/inward/record.url?scp=85027443270&partnerID=8YFLogxK.
    https://doi.org/10.3389/fcimb.2017.00114
Conference paper
  1. Ana Armada; Carlos Novo; do Rosario, Virgilio. "Preliminary results on the presence of proteases on malaria patient’s urine". Paper presented in 3rd European Congress on Tropical Medicine and International Health, 2012.
    Published
  2. Ana Gonçalves Domingos. "Aspartic proteases of the rodent malaria parasite Plasmodium chabaudi.". Paper presented in 3rd European Congress on Tropical Medicine and International Health, 2002.
    Published • doi10.1016/S0001-706X(03)00199-2
  3. Reis, Patrícia J. M.; Lourenço, Pedro L.; Domingos, Ana; Clemente, Alda; Malcata, F. Xavier. "Utilização de proteases de Centaurea calcitrapa L. no fabrico de queijo de vaca: efeitos microbiológicos". 1999.
Journal article
  1. Giglioti, Rodrigo; Filho, Anibal Eugênio Vercesi; Domingos, Ana Gonçalves; da Silva, Sérgio Silva; Cunha, Rodrigo Casquero; Ibelli, Adriana Mércia Guaratini; Okino, Cintia Hiromi; de Sena Oliveira, Márcia Cristina. "Detection and quantification of Babesia bovis and Babesia bigemina using different target genes". Research in Veterinary Science 168 (2023): 105122. http://dx.doi.org/10.1016/j.rvsc.2023.105122.
    10.1016/j.rvsc.2023.105122
  2. Alina Rodríguez-Mallon; Pedro E. Encinosa Guzmán; Yamil Bello; Ana Domingos; Sandra Antunes; Petr Kopacek; Ana Sofia Santos; et al. "Efficacy of the Vaccine Candidate Based on the P0 Peptide against Dermacentor nitens and Ixodes ricinus Ticks". Pathogens (2023): https://doi.org/10.3390/pathogens12111365.
    10.3390/pathogens12111365
  3. Rita Velez; Thierry De Meeûs; Lorenza Beati; Hend Younsi; Elyes Zhioua; Sandra Antunes; Ana Domingos; et al. "Development and testing of microsatellite loci for the study of population genetics of Ixodes ricinus Linnaeus, 1758 and Ixodes inopinatus Estrada-Peña, Nava and Petney, 2014 (Acari: Ixodidae) in the western Mediterranean region". Acarologia (2023): https://doi.org/10.24349/bvem-4h49.
    10.24349/bvem-4h49
  4. Sandra Antunes; Ana Domingos. "Tick Vaccines and Concealed versus Exposed Antigens". Pathogens (2023): https://doi.org/10.3390/pathogens12030374.
    10.3390/pathogens12030374
  5. Magdalena Szczotko; Katarzyna Kubiak; Miroslaw Mariusz Michalski; Leonardo Moerbeck; Sandra Antunes; Ana Domingos; Malgorzata Dmitryjuk. "Neoehrlichia mikurensis—A New Emerging Tick-Borne Pathogen in North-Eastern Poland?". Pathogens (2023): https://doi.org/10.3390/pathogens12020307.
    10.3390/pathogens12020307
  6. Patrícia Gonzaga Paulino; Maristela Peckle; Leo Paulis Mendonça; Carlos Luiz Massard; Sandra Antunes; Joana Couto; Ana Domingos; et al. "Differential Expression of Immune Genes in the Rhipicephalus microplus Gut in Response to Theileria equi Infection". Pathogens (2022): https://doi.org/10.3390/pathogens11121478.
    10.3390/pathogens11121478
  7. Leonardo Moerbeck; Ana Domingos; Sandra Antunes. "Tick-Borne Rickettsioses in the Iberian Peninsula". Pathogens (2022): https://doi.org/10.3390/pathogens11111377.
    10.3390/pathogens11111377
  8. Agustín Estrada-Peña; Alina Rodríguez Mallón; Sergio Bermúdez; José de la Fuente; Ana Domingos; Mario Pablo Estrada García; Marcelo B. Labruna; et al. "One Health Approach to Identify Research Needs on Rhipicephalus microplus Ticks in the Americas". Pathogens (2022): https://doi.org/10.3390/pathogens11101180.
    10.3390/pathogens11101180
  9. Estefania Torrejón; Gustavo Seron Sanches; Leonardo Moerbeck; Lenira Santos; Marcos Rogério André; Ana Domingos; Sandra Antunes. "Molecular Survey of Bartonella Species in Stray Cats and Dogs, Humans, and Questing Ticks from Portugal". Pathogens 11 7 (2022): 749-749. https://doi.org/10.3390/pathogens11070749.
    10.3390/pathogens11070749
  10. de la Fuente, José; Armas, Octavio; Sánchez-Rodríguez, Luis; Gortázar, Christian; Lukashev, Alexander N.; Almazán, Consuelo; Fernández de Mera, Isabel G.; et al. "Citizen science initiative points at childhood BCG vaccination as a risk factor for COVID-19". Transboundary and Emerging Diseases 68 6 (2021): 3114-3119. http://dx.doi.org/10.1111/tbed.14097.
    10.1111/tbed.14097
  11. Pacheco, Iván; Prado, Eduardo; Artigas-Jerónimo, Sara; Lima-Barbero, José Francisco; de la Fuente, Gabriela; Antunes, Sandra; Couto, Joana; et al. "Comparative analysis of Rhipicephalus tick salivary gland and cement elementome". Heliyon 7 4 (2021): e06721. http://dx.doi.org/10.1016/j.heliyon.2021.e06721.
    10.1016/j.heliyon.2021.e06721
  12. Joana Couto; Gonçalo Seixas; Christian Stutzer; Nicholas A. Olivier; Christine Maritz-Olivier; Sandra Antunes; Ana Domingos. "Probing the Rhipicephalus bursa Sialomes in Potential Anti-Tick Vaccine Candidates: A Reverse Vaccinology Approach". Biomedicines 9 4 (2021): 363-363. https://doi.org/10.3390/biomedicines9040363.
    10.3390/biomedicines9040363
  13. Patrícia Paulino; Gabriela Vitari; Antonio Rezende; Joana Couto; Sandra Antunes; Ana Domingos; Maristela Peckle; et al. "Characterization of the Rhipicephalus (Boophilus) microplus Sialotranscriptome Profile in Response to Theileria equi Infection". Pathogens 10 2 (2021): 167-167. https://doi.org/10.3390/pathogens10020167.
    10.3390/pathogens10020167
  14. Sanches, Gustavo Seron; Villar, Margarita; Couto, Joana; Ferrolho, Joana; Fernández de Mera, Isabel G.; André, Marcos Rogério; Barros-Battesti, Darci Moraes; et al. "Comparative Proteomic Analysis of Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) Tropical and Temperate Lineages: Uncovering Differences During Ehrlichia canis Infection". Frontiers in Cellular and Infection Microbiology 10 (2021): http://dx.doi.org/10.3389/fcimb.2020.611113.
    Published • 10.3389/fcimb.2020.611113
  15. Joana Couto; Margarita M. Villar-Rayo; Lourdes Mateos-Hernández; Joana Ferrolho; Gustavo S. Sanches; Ana Sofia Santos; Maria Margarida Santos-Silva; et al. "Quantitative Proteomics Identifies Metabolic Pathways Affected by Babesia Infection and Blood Feeding in the Sialoproteome of the Vector Rhipicephalus bursa". Vaccines (2020): https://www.mdpi.com/2076-393X/8/1/91.
    10.3390/vaccines8010091
  16. Estrada-Peña, Agustin; Nava, Santiago; Tarragona, Evelina; Bermúdez, Sergio; de la Fuente, José; Domingos, Ana; Labruna, Marcelo; et al. "Species occurrence of ticks in South America, and interactions with biotic and abiotic traits". Scientific Data 6 1 (2019): http://dx.doi.org/10.1038/s41597-019-0314-0.
    10.1038/s41597-019-0314-0
  17. Domingos, Ana. "Transient transfection of Babesia ovis using heterologous promoters.". Ticks and tick-borne diseases (2019): https://doi.org/10.1016/j.ttbdis.2019.101279.
    10.1016/j.ttbdis.2019.101279
  18. Domingos, Ana. "Folate pathway modulation in Rhipicephalus ticks in response to infection.". Transboundary and emerging diseases (2019): https://doi.org/10.1111/tbed.13231.
    10.1111/tbed.13231
  19. Domingos, Ana. "Transcriptome and Proteome Response of Rhipicephalus annulatus Tick Vector to Babesia bigemina Infection.". Frontiers in Physiology (2019): http://europepmc.org/articles/PMC6454348.
    10.3389/fphys.2019.00318
  20. Alina Rodríguez-Mallon; Jose Luis Cenis Anadón; Antonio Abel Lozano Pérez; Gervasio H. Bechara; Rosangela Zacarias Machado; Ricardo Lleonart Cruz; Ana Domingos; Alma R. Tamayo Sosa. "CYTED Network to develop an immunogen compatible with integrated management strategies for tick control in cattle". Vaccine 36 45 (2018): 6581-6586. https://doi.org/10.1016/j.vaccine.2018.09.064.
    10.1016/j.vaccine.2018.09.064
  21. Gustavo S. Sanches; Joana Couto; Rita Silva-Pedrosa; Joana Ferrolho; Ana Sofia Santos; Maria Margarida Santos-Silva; Sandra Antunes; Ana Domingos. "Molecular heterogeneity of Rhipicephalus sanguineus sensu lato and screening for Ehrlichia canis in mainland Portugal". Ticks and Tick-borne Diseases 9 6 (2018): 1383-1390. https://doi.org/10.1016/j.ttbdis.2018.06.002.
    10.1016/j.ttbdis.2018.06.002
  22. Ferrolho, Joana; Couto, Joana; Sanches, Gustavo Seron; Antunes, Sandra; Domingos, Ana Gonçalves. "The Secret Life Inside Ticks". Frontiers for Young Minds 6 (2018): http://dx.doi.org/10.3389/frym.2018.00035.
    10.3389/frym.2018.00035
  23. Joana Couto; Miray Tonk; Joana Ferrolho; Sandra Antunes; Andreas Vilcinskas; José de la Fuente; Ana Domingos; Alejandro Cabezas-Cruz. "Antiplasmodial activity of tick defensins in a mouse model of malaria". Ticks and Tick-borne Diseases 9 4 (2018): 844-849. https://doi.org/10.1016/j.ttbdis.2018.03.011.
    10.1016/j.ttbdis.2018.03.011
  24. Antunes, Sandra; Couto, Joana; Ferrolho, Joana; Rodrigues, Fabio; Nobre, Joao; Santos, Ana S.; Santos-Silva, M. Margarida; de la Fuente, Jose; Domingos, Ana. "Rhipicephalus bursa Sialotranscriptomic Response to Blood Feeding and Babesia ovis Infection: Identification of Candidate Protective Antigens". Frontiers in Cellular and Infection Microbiology 8 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000431438000001&KeyUID=WOS:000431438000001.
    10.3389/fcimb.2018.00116
  25. Antunes, Sandra; Lérias, Joana; Merino, Octávio; do Rosário, Virgílio; de la Fuente, José; Domingos, Ana. "Effect of polyclonal antibodies applied by artificial feeding to Rhipicephalus microplus ticks". (2018): http://anaisihmt.com/index.php/ihmt/article/view/191.
  26. Ana Marcília Matsimbe; Vlademiro Magaia; Gustavo Seron Sanches; Luís Neves; Emília Noormahomed; Sandra Antunes; Ana Domingos. "Molecular detection of pathogens in ticks infesting cattle in Nampula province, Mozambique". Experimental and Applied Acarology (2017): https://doi.org/10.1007/s10493-017-0155-5.
    10.1007/s10493-017-0155-5
  27. Domingos, Ana. "Solute carriers affect Anopheles stephensi survival and Plasmodium berghei infection in the salivary glands.". Scientific reports (2017): http://europepmc.org/abstract/med/28733628.
    10.1038/s41598-017-06317-6
  28. Ferrolho, Joana; Sanches, Gustavo S.; Couto, Joana; Antunes, Sandra; Domingos, Ana. "What Makes Your Dog Itch? Maybe It Is the Kennel Tick!". Frontiers for Young Minds 5 (2017): http://dx.doi.org/10.3389/frym.2017.00028.
    10.3389/frym.2017.00028
  29. Domingos, Ana. "Inhibition of the in vitro growth of Babesia bigemina, Babesia caballi and Theileria equi parasites by trifluralin analogues.". Ticks and tick-borne diseases (2017): http://europepmc.org/abstract/med/28416183.
    10.1016/j.ttbdis.2017.04.002
  30. A. Domingos; R. Pinheiro-Silva; J. Couto; V. do Rosário; J. de la Fuente. "The Anopheles gambiae transcriptome - a turning point for malaria control". Insect Molecular Biology (2017): https://doi.org/10.1111%2Fimb.12289.
    10.1111/imb.12289
  31. Domingos, Ana. "Prion protein 2 (dublet) gene (PRND): Role in ovine semen capacitation, cryopreservation and fertility". Reproduction, Fertility and Development (2017):
    doi: 10.1071/RD15214.
  32. Silaghi C; Santos AS; Gomes J; Christova I; Matei IA; Walder G; Domingos A; et al. "Guidelines for the Direct Detection of Anaplasma spp. in Diagnosis and Epidemiological Studies.". (2017): http://europepmc.org/abstract/med/28055579.
  33. Lempereur L; Beck R; Fonseca I; Marques C; Duarte A; Santos M; Zúquete S; et al. "Guidelines for the Detection of Babesia and Theileria Parasites.". (2017): http://europepmc.org/abstract/med/28055573.
  34. Ferrolho J; Antunes S; Sanches GS; Couto J; Évora PM; Rosa C; André MR; et al. "Ferritin 1 silencing effect in Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) during experimental infection with Ehrlichia canis.". (2017): http://europepmc.org/abstract/med/27825659.
    10.1016/j.ttbdis.2016.10.015
  35. J. Couto; S. Antunes; J. Ferrolho; J. de la Fuente; A. Domingos. "Reduction of Mosquito Survival in Mice Vaccinated with Anopheles stephensi Glucose Transporter". BioMed Research International (2017):
    10.1155/2017/3428186
  36. Domingos, Ana. "Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases.". Frontiers in cellular and infection microbiology (2017): http://europepmc.org/abstract/med/28439499.
    10.3389/fcimb.2017.00114
  37. Antunes, Sandra; Rosa, Catarina; Couto, Joana; Ferrolho, Joana; Domingos, Ana; Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM); Vector borne diseases and pathogens (VBD); Domingos, Ana. "Deciphering babesia-vector interactions". Front. Cell. Infect. Microbiol. (2017): http://www.scopus.com/inward/record.url?scp=85031399495&partnerID=8YFLogxK.
    https://doi.org/10.3389/fcimb.2017.00429
  38. Elelu N; Ferrolho J; Couto J; Domingos A; Eisler MC. "Molecular diagnosis of the tick-borne pathogen Anaplasma marginale in cattle blood samples from Nigeria using qPCR.". (2016): http://europepmc.org/abstract/med/27787614.
    10.1007/s10493-016-0081-y
  39. Santos-Silva MM; Melo P; Santos N; Antunes S; Duarte LR; Ferrolho J; Milhano N; et al. "PCR screening of tick-borne agents in sensitive conservation areas, Southeast Portugal.". (2016): http://europepmc.org/abstract/med/27894847.
    10.1016/j.mcp.2016.11.005
  40. Antunes S; Ferrolho J; Domingues N; Santos AS; Santos-Silva MM; Domingos A. "Anaplasma marginale and Theileria annulata in questing ticks from Portugal.". (2016): http://europepmc.org/abstract/med/27394441.
    10.1007/s10493-016-0057-y
  41. Joana Ferrolho; Sandra Antunes; Ana S. Santos; Rita Velez; Ludovina Padre; Alejandro Cabezas-Cruz; Maria Margarida Santos-Silva; et al. "Detection and phylogenetic characterization of Theileria spp. and Anaplasma marginale in Rhipicephalus bursa in Portugal". Ticks and Tick-borne Diseases 7 3 (2016): 443-448. http://dx.doi.org/10.1016/j.ttbdis.2016.01.004.
    10.1016/j.ttbdis.2016.01.004
  42. Domingos, Ana. "Anopheles gambiae and A. stephensi Immune Response during Plasmodium berghei Infection Uncovered by Sialotranscriptomic Analysis". Int. Trends in Immunity 4 2 (2016): 58-72.
    Open access • Published • 10.18281/iti.2016.2.4.
  43. Contreras M; Moreno-Cid JA; Domingos A; Canales M; Díez-Delgado I; Pérez de la Lastra JM; Sánchez E; et al. "Bacterial membranes enhance the immunogenicity and protective capacity of the surface exposed tick Subolesin-Anaplasma marginale MSP1a chimeric antigen.". (2015): http://europepmc.org/abstract/med/26219233.
    10.1016/j.ttbdis.2015.07.010
  44. Antunes S; Merino O; Lérias J; Domingues N; Mosqueda J; de la Fuente J; Domingos A. "Artificial feeding of Rhipicephalus microplus female ticks with anti calreticulin serum do not influence tick and Babesia bigemina acquisition.". (2015): http://europepmc.org/abstract/med/25262467.
    10.1016/j.ttbdis.2014.09.003
  45. Domingos, A.. "Proteomic informed by transcriptomic towards the selection of vaccine candidate against vector-borne diseases". Tropical Medicine & International Health 20 (2015): 424-424. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000360758802301&KeyUID=WOS:000360758802301.
  46. Domingos A; Antunes S; Villar M; de la Fuente J. "Functional genomics of tick vectors challenged with the cattle parasite Babesia bigemina.". (2015): http://europepmc.org/abstract/med/25399115.
    10.1007/978-1-4939-2004-4_32
  47. Pinheiro-Silva, Renato; Borges, Lara; Coelho, Luís Pedro; Cabezas-Cruz, Alejandro; Valdés, James J.; Do Rosário, Virgílio; De La Fuente, José; et al. "Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection". (2015): http://www.scopus.com/inward/record.url?scp=84942328850&partnerID=8YFLogxK.
    https://doi.org/10.1186/s13071-015-1079-8
  48. Ana Gonçalves Domingos. "The regulatory CD4+CD25+T cell subset in host homeostasis during protozoan infection: an overview". Int. Trends in Immunity 3 1 (2015): 6-16.
    Published
  49. da Costa M; Pinheiro-Silva R; Antunes S; Moreno-Cid JA; Custódio A; Villar M; Silveira H; de la Fuente J; Domingos A. "Mosquito Akirin as a potential antigen for malaria control.". (2014): http://europepmc.org/abstract/med/25472895.
    10.1186/1475-2875-13-470
  50. Antunes S; Merino O; Mosqueda J; Moreno-Cid JA; Bell-Sakyi L; Fragkoudis R; Weisheit S; et al. "Tick capillary feeding for the study of proteins involved in tick-pathogen interactions as potential antigens for the control of tick infestation and pathogen infection.". (2014): http://europepmc.org/abstract/med/24450836.
    10.1186/1756-3305-7-42
  51. Fafetine, J.M.; Domingos, A.; Antunes, S.; Esteves, A.; Paweska, J.T.; Coetzer, J.A.W.; Rutten, V.P.M.G.; Neves, L.. "Generation and Characterization of Monoclonal Antibodies Against Rift Valley Fever Virus Nucleoprotein". Transboundary and Emerging Diseases 60 SUPPL.2 (2013): 24-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887368964&partnerID=MN8TOARS.
    10.1111/tbed.12140
  52. Silva, M.G.; Domingos, A.; Esteves, M.A.; Cruz, M.E.M.; Suarez, C.E.. "Evaluation of the growth-inhibitory effect of trifluralin analogues on in vitro cultured Babesia bovis parasites". International Journal for Parasitology: Drugs and Drug Resistance 3 (2013): 59-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873974204&partnerID=MN8TOARS.
    10.1016/j.ijpddr.2013.01.003
  53. Pimenta, J.; Sardinha, J.; Marques, C.C.; Domingos, A.; Baptista, M.C.; Barbas, J.P.; Martins, I.C.; et al. "Inhibition of ovine in vitro fertilization by anti-Prt antibody: Hypothetical model for Prt/ZP interaction". Reproductive Biology and Endocrinology 11 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875307776&partnerID=MN8TOARS.
    10.1186/1477-7827-11-25
  54. Domingos, A.; Antunes, S.; Borges, L.; Do Rosário, V.E.. "Approaches towards tick and tick-borne diseases control". Revista da Sociedade Brasileira de Medicina Tropical 46 3 (2013): 265-269. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880026193&partnerID=MN8TOARS.
    10.1590/0037-8682-0014-2012
  55. Popara, M.; Villar, M.; Mateos-Hernández, L.; de Mera, I.G.F.; Marina, A.; del Valle, M.; Almazán, C.; Domingos, A.; de la Fuente, J.. "Lesser protein degradation machinery correlates with higher BM86 tick vaccine efficacy in Rhipicephalus annulatus when compared to Rhipicephalus microplus". Vaccine 31 42 (2013): 4728-4735. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884209801&partnerID=MN8TOARS.
    10.1016/j.vaccine.2013.08.031
  56. Merino, O.; Antunes, S.; Mosqueda, J.; Moreno-Cid, J.A.; Pérez de la Lastra, J.M.; Rosario-Cruz, R.; Rodríguez, S.; Domingos, A.; de la Fuente, J.. "Vaccination with proteins involved in tick-pathogen interactions reduces vector infestations and pathogen infection". Vaccine (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84885144503&partnerID=MN8TOARS.
    10.1016/j.vaccine.2013.09.037
  57. Armada, A.; Gazarini, M.L.; Gonçalves, L.M.; Antunes, S.; Custódio, A.; Rodrigues, A.; Almeida, A.J.; et al. "Generation of an antibody that recognizes Plasmodium chabaudi cysteine protease (chabaupain-1) in both sexual and asexual parasite life cycle and evaluation of chabaupain-1 vaccine potential". Experimental Parasitology 135 1 (2013): 166-174. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882761205&partnerID=MN8TOARS.
    10.1016/j.exppara.2013.06.009
  58. Pérez, B.; Antunes, S.; Gonçalves, L.M.; Domingos, A.; Gomes, J.R.B.; Gomes, P.; Teixeira, C.; Faculdade de Ciências. "Toward the discovery of inhibitors of babesipain-1, a Babesia bigemina cysteine protease: In vitro evaluation, homology modeling and molecular docking studies". Journal of Computer-Aided Molecular Design 27 9 (2013): 823-835. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887039079&partnerID=MN8TOARS.
    10.1007/s10822-013-9682-2
  59. Silva, R.; do Rosario, V.; de la Fuente, J.; Domingos, A.. "Identification of genes differentially expressed in Anopheles gambiae salivary glands in response to infection with Plasmodium berghei". Tropical Medicine & International Health 18 (2013): 155-155. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000324029000422&KeyUID=WOS:000324029000422.
  60. Ana Gonçalves Domingos. "Alimentação artificial de Rhipicephalus microplus: Avaliação do efeito de anticorpos policlonais.". Anais do Instituto de Higiene e Medicina Tropical 12 (2013):
    Published
  61. Ana Gonçalves Domingos. "Análise funcional de genes aplicada ao desenvolvimento de vacinas contra carraças e seus agentes etiológicos". Acta Parasitológica Portuguesa 18 (2013): 53-62.
    Published
  62. Antunes, S.; Galindo, R.C.; Almazán, C.; Rudenko, N.; Golovchenko, M.; Grubhoffer, L.; Shkap, V.; et al. "Functional genomics studies of Rhipicephalus (Boophilus) annulatus ticks in response to infection with the cattle protozoan parasite, Babesia bigemina". International Journal for Parasitology 42 2 (2012): 187-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856502455&partnerID=MN8TOARS.
    10.1016/j.ijpara.2011.12.003
  63. Pimenta, J.; Domingos, A.; Santos, P.; Marques, C.C.; Cantante, C.; Santos, A.; Barbas, J.P.; et al. "Is prnt a pseudogene? identification of ram prt in testis and ejaculated spermatozoa". PLoS ONE 7 8 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865296947&partnerID=MN8TOARS.
    10.1371/journal.pone.0042957
  64. Martins, T.M.; do Rosário, V.E.; Domingos, A.. "Expression and characterization of the Babesia bigemina cysteine protease BbiCPL1". Acta Tropica 121 1 (2012): 1-5. http://www.scopus.com/inward/record.url?eid=2-s2.0-81255136137&partnerID=MN8TOARS.
    10.1016/j.actatropica.2011.09.008
  65. Awad, H.; Antunes, S.; Galindo, R.C.; do Rosário, V.E.; de la Fuente, J.; Domingos, A.; El Hussein, A.M.. "Prevalence and genetic diversity of Babesia and Anaplasma species in cattle in Sudan". Veterinary Parasitology 181 2-4 (2011): 146-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052543727&partnerID=MN8TOARS.
    10.1016/j.vetpar.2011.04.007
  66. Martins, T.M.; do Rosário, V.E.; Domingos, A.. "Identification of papain-like cysteine proteases from the bovine piroplasm Babesia bigemina and evolutionary relationship of piroplasms C1 family of cysteine proteases". Experimental Parasitology 127 1 (2011): 184-194. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650532877&partnerID=MN8TOARS.
    10.1016/j.exppara.2010.07.012
  67. Martins, T.M.; Gonçalves, L.M.D.; Capela, R.; Moreira, R.; do Rosário, V.E.; Domingos, A.. "Effect of synthesized inhibitors on Babesipain-1, a new cysteine protease from the bovine piroplasm Babesia bigemina". Transboundary and Emerging Diseases 57 1-2 (2010): 68-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954450507&partnerID=MN8TOARS.
    10.1111/j.1865-1682.2010.01102.x
  68. Martins, T.M.; Neves, L.; Pedro, O.C.; Fafetine, J.M.; Do Rosário, V.E.; Domingos, A.. "Molecular detection of Babesia spp. and other haemoparasitic infections of cattle in Maputo Province, Mozambique". Parasitology 137 6 (2010): 939-946. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953614417&partnerID=MN8TOARS.
    10.1017/S003118200999196X
  69. Capela, R.; Oliveira, R.; Gonçalves, L.M.; Domingos, A.; Gut, J.; Rosenthal, P.J.; Lopes, F.; Moreira, R.. "Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: Design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition". Bioorganic and Medicinal Chemistry Letters 19 12 (2009): 3229-3232. http://www.scopus.com/inward/record.url?eid=2-s2.0-65749094248&partnerID=MN8TOARS.
    10.1016/j.bmcl.2009.04.100
  70. Caldeira, R.L.; Gonçalves, L.M.D.; Martins, T.M.; Silveira, H.; Novo, C.; Rosário, V.d.; Domingos, A.. "Plasmodium chabaudi: Expression of active recombinant chabaupain-1 and localization studies in Anopheles sp.". Experimental Parasitology 122 2 (2009): 97-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-65749109757&partnerID=MN8TOARS.
    10.1016/j.exppara.2009.03.003
  71. Caldeira, Rubina L.; Goncalves, Lidia M. D.; Martins, Tiago M.; Silveira, Henrique; Novo, Carlos; do Rosario, Virgilio; Domingos, Ana. "Plasmodium chabaudi". (2009): http://hdl.handle.net/10451/21317.
    http://dx.doi.org/10.1016/j.exppara.2009.03.003
  72. Capela, Rita; Oliveira, Rudi; Goncalves, Lidia M.; Domingos, Ana; Gut, Jiri; Rosenthal, Philip J.; Lopes, Francisca; Moreira, Rui. "Artemisinin-dipeptidyl vinyl sulfone hybrid molecules". (2009): http://hdl.handle.net/10451/21198.
    http://dx.doi.org/10.1016/j.bmcl.2009.04.100
  73. Martins, Tiago M.; Pedro, Olívia C.; Rubina, Caldeira; Rosário, Virgílio do; Neves, L.; Domingos, Ana; Martins, T.M.; et al. "Detection of bovine Babesiosis in Mozambique by a novel seminested hot-start PCR method.". Veterinary Parasitology 153 3-4 (2008): 225-230. http://hdl.handle.net/10400.9/1042.
    10.1016/j.vetpar.2008.01.037
  74. Raposo, Sara; Domingos, Ana; Raposo, S.; Domingos, A.. "Purification and characterization milk-clotting aspartic proteinases from Centaurea calcitrapa cell suspension cultures". Process Biochemistry 43 2 (2008): 139-144. http://hdl.handle.net/10400.1/4797.
    http://dx.doi.org/ 10.1016/j.procbio.2007.11.003
  75. Salvador, S.M.; Novo, C.; Domingos, A.. "Evaluation of the presence of aspartic proteases from Centaurea calcitrapa during seed germination". Enzyme and Microbial Technology 38 7 (2006): 893-898. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645223242&partnerID=MN8TOARS.
    10.1016/j.enzmictec.2005.06.025
  76. Martins, T.M.; Domingos, A.; Berry, C.; Wyatt, D.M.. "The activity and inhibition of the food vacuole plasmepsin from the rodent malaria parasite Plasmodium chabaudi". Acta Tropica 97 2 (2006): 212-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-30644473620&partnerID=MN8TOARS.
    10.1016/j.actatropica.2005.11.001
  77. Martins, T.M.; Domingos, A.; Novo, C.; Lourenço, P.M.L.. "Effect of Agrobacterium rhizogenes infection on in vitro rooting of Vitis vinifera". Vitis 42 3 (2003): 159-161. http://www.scopus.com/inward/record.url?eid=2-s2.0-0142060031&partnerID=MN8TOARS.
  78. Martins, T.M.; Novo, C.; Do Rosário, V.E.; Domingos, A.. "Aspartic proteases from Plasmodium chabaudi: A rodent model for human malaria". Acta Tropica 89 1 (2003): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242493166&partnerID=MN8TOARS.
    10.1016/S0001-706X(03)00199-2
  79. Lourenço, P.M.L.; De Castro, S.; Martins, T.M.; Clemente, A.; Domingos, A.. "Growth and proteolytic activity of hairy roots from Centaurea calcitrapa: Effect of nitrogen and sucrose". Enzyme and Microbial Technology 31 3 (2002): 242-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037008379&partnerID=MN8TOARS.
    10.1016/S0141-0229(02)00117-5
  80. Clemente, A.; Domingos, A.; Grancho, A.P; Iley, J.; Moreira, R.; Neres, J.; Palma, N.; Santana, A.B; Valente, E.. "Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors". Bioorganic and Medicinal Chemistry Letters 11 8 (2001): 1065-1068. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035938401&partnerID=MN8TOARS.
    10.1016/S0960-894X(01)00131-7
  81. Novo, C.; Domingos, A.; Karmali, A.. "Purification and characterization of monoclonal antibodies against the free a-subunit of human chorionic gonadotrophin". Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology 17 2 (2001): 119-128. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034998636&partnerID=MN8TOARS.
    10.1385/MB:17:2:119
  82. Domingos A; Cardoso PC; Xue ZT; Clemente A; Brodelius PE; Pais MS. "Purification, cloning and autoproteolytic processing of an aspartic proteinase from Centaurea calcitrapa.". (2000): http://europepmc.org/abstract/med/11082193.
    10.1046/j.1432-1033.2000.01780.x
  83. Reis, Patrícia M.; Lourenço, Pedro L.; Domingos, Ana; Clemente, Alda F.; Reis, P.M.; Lourenço, P.L.; Domingos, A.; et al. "Applicability of extracts from Centaurea calcitrapa in ripening of bovine cheese". International Dairy Journal 10 11 (2000): 775-780. http://hdl.handle.net/10400.14/6882.
    10.1016/S0958-6946(00)00105-9
  84. Domingos A; Xue ZT; Guruprasad K; Clemente A; Blundell T; Pais MS; Brodelius PE. "An aspartic proteinase from flowers of Centaurea calcitrapa. Purification, characterization, molecular cloning, and modelling of its three-dimensional structure.". (1998): http://europepmc.org/abstract/med/9561254.
  85. Brodelius, P.E.; Cordeiro, M.; Mercke, P.; Domingos, A.; Clemente, A.; Pais, M.S.. "Molecular cloning of aspartic proteinases from flowers of Cynara cardunculus subsp. flavescens cv. cardoon and Centaurea calcitrapa". Advances in Experimental Medicine and Biology 436 (1998): 435-439. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031894720&partnerID=MN8TOARS.
  86. Tavaria, F.K.; Sousa, M.J.; Domingos, A.; Malcata, F.X.; Brodelius, P.; Clemente, A.; Pais, M.S.; et al. "Degradation of Caseins from Milk of Different Species by Extracts of Centaurea calcitrapa". Journal of Agricultural and Food Chemistry 45 10 (1997): 3760-3765. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001357634&partnerID=MN8TOARS.
  87. Karmali, A.; Domingos, A.. "Monoclonal antibodies against urease from Canavalia ensiformis". Biochimie 75 11 (1993): 1001-1006. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027788117&partnerID=MN8TOARS.
    10.1016/0300-9084(93)90152-I
  88. Domingos, Ana. "One-step affinity purification of amidase from mutant strains of Pseudomonas aeruginosa.". Biochimie (1989): http://europepmc.org/abstract/med/2517478.
    10.1016/0300-9084(89)90021-7
Thesis / Dissertation
  1. "Biologia Molecular Aplicada ao Estudo da Babesiose (Agregação)". Degree, Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, 2011.
  2. Domingos, Ana. "An aspartic proteinase from flowers of Centaurea calcitrapa: purification, molecular cloning and modelling of its three-dimensional structure". PhD, Fundação da Faculdade de Ciências da Universidade de Lisboa, 1997.
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2020/10/01 - Current Characterization of the Hazara virus and tick cell lines interactions towards Crimean-Congo hemorrhagic fever virus control
Co-supervisor
Virus and tick cell lines characterization and infection. (Master)
Universidade Nova de Lisboa, Portugal
2019/01/01 - Current Tick and parasite interactions.
Supervisor
Tick and parasite interactions. (Other)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2017/10/01 - Current Microbiota and pathogens harboured by hard ticks throughout Portugal.
Co-supervisor of Leonardo Moerbeck da Costa Moreira
Tick microbiome and epidemiology (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2017/04/01 - Current TickProVac: An insight into the Rhipicephalus sanguineus tick salivary gland proteome during Ehrlichia canis infection towards vaccine development.
Supervisor
Tick proteomic and functional analysis. Erlichia canis infection. (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/01/11 - 2022/04/10 In vitro evaluation of an acaricide effect on embryo tick cell lines non-infected and infected with Ehrlichia canis..
Supervisor
Tick vector control (PhD)
Universidade Estadual Paulista Júlio de Mesquita Filho Instituto de Artes de São Paulo, Brazil
2018/09/01 - 2022/03/30 Exploring the interactome of tick-host towards vaccine development.
Supervisor
Tick genomics and proteomics. Reverse immunology. Vaccination. (Other)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/07 - 2021/12/06 Detection of Candidatus Neoehrlichia mikurensis and Borrelia burgdorferi sensu lato in Ixodes ricinus ticks from urban and natural forested areas of Northeastern Poland.
Supervisor
Tick pathogens detection. (Other)
Universidade Nova de Lisboa, Portugal
2021/10/06 - 2021/10/20 Detection of tick zoonotic parasites by molecular methods.
Supervisor
Tick zoonotic pathogens identification. (Other)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/11 - 2021/10/11 Evaluation of the efficiency of the immunization with recombinant peptides in the control of R. bursa infestations and B. ovis.
Supervisor
Evaluation of vaccines on tick survival and development. (Scientific initiation)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2017/01/02 - 2021/09/20 Vector pathogen interactomics: conneting the dots.
Supervisor
Biomedical Sciences (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/09/15 - 2020/03/03 Molecular Detection of Bartonella spp. in humans, domestic animals and ectoparasites sampled in Lisbon, Portugal.
Supervisor of Estefania Navarro
Epidemiology (Master)
Universidade Nova de Lisboa, Portugal
2017/09/01 - 2018/12/15 Regulation of the apoptosis pathway in Rhipicephalus annulatus ticks by the protozoan Babesia bigemina.
Supervisor of Filipa Dias
Vector parasite interactions. (Master)
Universidade de Aveiro, Portugal
2017 - 2018 Caracterização da via metabólica de apoptose na interação Rhipicephalus spp. –Babesia spp.
Supervisor of Catarina Monteiro
Vector - parasite interactions. (Master)
Universidade Nova de Lisboa, Portugal
2015/03/06 - 2016/09/06 Functional genomics of Rhipicephalus bursa – Babesia ovis interactions towards disease control.
Co-supervisor
Parasite and vector interaction (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/09/15 - 2015/11/20 Funcional analysis of genes differentially expressed in salivary glands of Anopheles coluzzii and Anopheles stephensi in response to infection by Plasmodium berghei
Supervisor
Malaria. Transcriptomics. Gene silencing. (PhD)
Universidade Nova de Lisboa, Portugal
2013/09/10 - 2015/07/07 Transcriptomic analysis of Anopheles Stephensi salivary glands during the infection with Plasmodium Berghei
Supervisor of Joana Couto
Malaria. Transcriptomics (Master)
Universidade de Aveiro, Portugal
2010 - 2014 Differential expression and functional characterization of cattle tick genes in response to pathogen infection (Babesia bigemina)
Supervisor of Sandra Antunes
Vector differential dene expression upon parasite infection (PhD)
Universidade Nova de Lisboa, Portugal
2011 - 2012/05/17 Expression and characterization of calreticulin gene isolated from Rhipicephalus annulatus after Babesia bigemina infection.
Supervisor of Joana Lérias
Recombinant proteins expression. (Master)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2010 - 2012 Estudos do efeito da proteína recombinante Akirin na infeção por Plasmodium berghei em Anopheles gambiae s.s.
Supervisor
malaria. vaccines (Master)
Universidade Nova de Lisboa, Portugal
2006 - 2010 Identification of proteases as diagnostic and therapeutic targets for bovine babbesiosis.
Supervisor of Tiago Martins
Proteases. Babesiosis. Tick diseases. (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2007 - 2009 Isolamento de inibidores de proteases a partir de culturas de células vegetais com actividade antimalárica.
Supervisor
Cell cultures. Anti-malarial inhibitors. (Master)

Event participation

Activity description
Type of event
Event name
Institution / Organization
2022/02/22 - Current Speaker
Conference
2ª Edição do NOVA Quality Day
Universidade Nova de Lisboa, Portugal
2021/06 - Current Student/attendee.
Other
Course for teaching skills improvement. Curso de formação de professores.
Universidade Nova de Lisboa, Portugal
2021/03/24 - Current Chair of three sessions.
Conference
14th International Symposium on Ticks and Tick-borne Diseases

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2021/09/20 Vector-pathogen interactomics: connecting the dots
Supervisor
Joana Manuel Gonçalves Teixeira Couto (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/07/27 Detección de Leishmania spp. en reservorios atípicos y caracterización molecular
(Thesis) Main arguer
María Victoria Ortega García (PhD)
Universidad Complutense de Madrid, Spain
2021/06/21 The role of a-Gal (Gala1-3Galß1-4GlcNAc-R) on Plasmodium spp. sporozoites in Anopheles spp. mosquito salivary glands invasion.
(Thesis) Main arguer
Hélio Daniel Ribeiro Rocha (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2019/12/19 Identification of vaccine candidates for the control of Dermanyssus gallinae: A One Health issue.
Thesis Member
José Francisco Lima Barbero (PhD)
Instituto de Investigación en Recursos Cinegéticos, Spain

Association member

Society Organization name Role
2010 - Current R&D center GHTM – Global Health and Tropical Medicine.Reserach Center Reseracher at the Vector Borne Diseases Group
1999 - 2010 CMDT- Center for malaria and other tropical diseases Researcher

Conference scientific committee

Conference name Conference host
2024/08 - Current
2024 - 2024 11th Tick & Tick-borne Pathogen Conference Centro de Ingeniería Genética y Biotecnología, Cuba
2022 - 2022 26th Congress of the Polish Parasitological Society University of Warmia and Mazury, Olsztyn, Poland
2019/12/15 - 2019/12/18 Bioticks 2019: The challenge of tick control, Varadero, Cuba. Centro de Ingeniería Genética y Biotecnología, Cuba
2015 - 2015 Vectors and parasites in Global Health IHMT-UNL
2014 - 2014 Vectors of human and animal disease: from epidemiology to control FMV, IICT, INSA. IHMT-UNL
2011 - 2011 On control, diagnosis and epidemiology in tick and tick-borne Diseases IHMT-UNL
2009 - 2009 Functional Genomics of Tick-Anaplasma Interactions and Vaccine Development IHMT-UNL

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2016 - Current Genomics and proteomics: 1. Microarrays and RNA sequencing. 2. Gene expression in procarionts. Biomedical Sciences (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - Current Protozoology: 1. Babesia and Theileria genus 2- PCR detection of Babesia and Theileria Medical Parasitology (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - Current Translational research. Ciências Biomédicas (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - Current Translational research. TROPIKMAn - TROPICAL KNOWLEDGE AND MANAGEMENT (Doktor (PhD)) Universidade Nova de Lisboa Nova School of Business and Economics, Portugal
2014 - Current Scientific writing Biomedical Sciences (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014 - Current Monoclonal antibody production Biotechnology (Master) Universidade Eduardo Mondlane, Mozambique

Journal scientific committee

Journal title (ISSN) Publisher
2020 - Current Annals of Medicine Taylor and Francis
2019 - Current Pathogens MDPI, Multidisciplinary Digital Publishing Institute
2019 - Current Journal of Veterinary Science and Research RAFT Publications
2018 - Current Scientific Reports Nature
2018 - Current Vaccines MPDI