Personal identification

Full name

Paula Cristina Veríssimo Pires

Citation names

• Pires, Paula
• Paula Veríssimo

Author identifiers

Ciência ID

B917-929D-23FC

ORCID iD

0000-0003-0532-4242

Google Scholar ID

https://scholar.google.com/citations?user=9GIiEiIAAAAJ&hl=pt-PT

Scopus Author Id

https://www.scopus.com/authid/detail.uri?authorId=7003870479

Email addresses

• pverissimo@bioq.uc.pt (Professional)

Telephones

Telephone

• 304502911 (Professional)

Addresses

• Centro de Neurociências de Coimbra. Department of Life Science, University of Coimbra, Apartado 3126, 3000, Coimbra, Coimbra, Portugal (Professional)

Websites

• https://www.researchgate.net/profile/Paula-Verissimo (Scholar)

Knowledge fields

• Natural sciences - Biological Sciences - Biochemistry

	Degree	Classification
1996 Concluded	Bioquímica (Doutoramento) Major in Especialidade: Enzimologia Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Cardosina a e Cardosina B: Proteases Aspárticas de Cynara Cardunculus L. Purificação, Caracterização e Sequência Parcial de Aminoácidos" (THESIS/DISSERTATION)
1991 Concluded	Biologia (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal	15 valores

Teaching in Higher Education

	Category Host institution	Employer
2000 - Current	Assistant Professor (University Teacher)	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Positions / Appointments

	Category Host institution	Employer
2022/02 - Current	Organic Unit Sub-director	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2021	Coordinator of the MSc in Biochemistry	Universidade de Coimbra Departamento de Ciências da Vida, Portugal
	Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2017 - 2019	Subdirector Departamento	Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2015 - 2017	Subdirector Departamento	Universidade de Coimbra Departamento de Ciências da Vida, Portugal
	Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Others

	Category Host institution	Employer
1997 - 2000	Pos-doctoral fellow	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1992 - 1996	PhD student	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Grant

	Designation	Funders
2002 - 2006	BIOCHEMICAL AND MOLECULAR ANALYSIS OF HEPSIN, A MEMBRANE SERINE PROTEASE IMPLICATED IN PROSTATE CANCER 49334 POCTI/CBO/49334/2002	Fundação para a Ciência e a Tecnologia, I.P.
2002 - 2005	CR(VI)-INDUCED GENOTOXIC STRESS: THE SIGNALLING MECHANISMS THAT LINK CELL CYCLE AND CELL FATE 48631 Researcher	Universidade do Algarve Faculdade de Ciências e Tecnologia Concluded
1998 - 2000	PRAXIS /P/BIA/11160/1998 Expressão e caracterização de uma protease serínica recombinante do polen de Parietária judaica PRAXIS /P/BIA/11160/1998 Post-doc Fellow CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2013 - 2015	FungiSensor: Biossensor de Toxicidade e Identificação de Biomoléculas em Fungos 34076 Researcher	Concluded
2008/05/23 - 2012/05/22	Proteases de Polens, relevância nas doenças alérgicas PTDC/SAU-ESA/72571/2006 Principal investigator Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2008/01/01 - 2011/12/31	BIOINK - Aprendizagem Incremental de "Kernel Machines" para Análise de Dados em Bioinformática PTDC/EIA/71770/2006 Universidade de Coimbra, Portugal Universidade de Coimbra Centro de Informatica e Sistemas, Portugal Instituto Politécnico de Coimbra, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2006 - 2008	Programa de Cooperacão GRICES-SECYT : Peptidases Vegetais com aplicação alimentar PO/PA05-BI/004 Researcher	Concluded
2003 - 2007	Programa de Cooperação Multilateral CYTED- Projecto IV.22 ¿Aplicação Industrial de Enzimas Proteolíticas de Vegetais superiores¿- 2003-2007 Programa de Cooperação Multilateral CYTED- Projecto IV.22 Programa de Cooperação Multilateral CYTED- Projecto IV.22 Post-doc Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	N/A Concluded
2002 - 2006	Biochemical and molecular analysis of hepsin, a membrane serine protease implicated in prostate cancer POCTI/CBO/49334/2002 Post-doc	Concluded
2003 - 2005	ASPARTIC PROTEINASE CONTENT OF ARABIDOPSIS GENOME: IDENTIFICATION, EXPRESSION AND CHARACTERIZATION 48400 POCTI/BCI/2002 POCTI/BCI/2002 Researcher CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2000/07/01 - 2003/09/30	CHARACTERIZATION, PRIMARY STRUCTURE AND HETEROLOGOUS EXPRESSION OF A SERINE PROTEASE OF THE POLLEN OF PARIETARIA JUDAICA SFRH/BPD/1615/2000 Post-doc Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1998 - 2001	Structure and function of PSI, the saposin-like domain of procardosin A PRAXIS/C/BIA/11168/98 CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1997 - 2001	Localization and biological function of cardosins PRAXIS/PCNA/BIA/0171/96 Researcher CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1997/04/01 - 2000/03/31	PROTEOLYTIC PROCESSING OF CARDOSIN B, AN ASPARTIC PROTEINASE FROM THE FLOWERS OF CARDOON PRAXIS XXI/BPD/11824/97 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1996 - 1999	PRAXIS XXI 2/2.1/BIO/1121/95 IMPACTO PRAXIS XXI 2/2.1/BIO/1121/95 Researcher	Concluded
1995 - 1998	PRAXIS XXI 2/2.1/BIO/20/94Microorganismos em ambientes extremos: mecanismos de adaptação PRAXIS XXI 2/2.1/BIO/20/94 Researcher CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1995 - 1998	Identificação e caracterização de novas enzimas coagulantes de origem vegetal PBIC/C/BIO/2002/95 Researcher	Fundação para a Ciência e a Tecnologia Concluded
1994 - 1997	PRAXIS XXI 2/2.1/QUI/17/94 Cristalografia Molecular PRAXIS XXI 2/2.1/QUI/17/94 Researcher	Concluded
1994/10/01 - 1995/09/30	CARACTERIZAÇÃO FÍSICO-QUÍMICA DAS FORMAS ACTIVAS DAS PROTEASES DE CYNARA CARDUNCULUS L PRAXIS XXI/BD/3987/94 Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1992 - 1995	PAMAF 95.09.6547.5 Melhoramento da produção do queijo Serra PAMAF 95.09.6547.5 Researcher

Other

	Designation	Funders
2001 - 2005	X-Prot- unidade de produção de proteínas recombinantes PRAI 3.1/2001 Researcher	European Commission Seventh Framework Programme for Research and Technological Development IDEAS The European Research Council Concluded

Publications

Book chapter	Tiago Parracho; Daniela C. Vaz; Paula Veríssimo; Vânia Ribeiro. "Green Biomaterials: Applications of Plant-Derived Biofilms". 2023. 10.1007/978-3-031-26849-6_29 Tiago Parracho; Daniela C. Vaz; Paula Veríssimo; Vânia Ribeiro. "Sand-Dune Plants from the Atlantic Coast of the Iberian Peninsula: Features and Applications". 127-136. Springer International Publishing, 2021. 10.1007/978-3-030-75315-3_15 Correia, D.; Pereira, C.; Veríssimo, P.; Dourado, A.. "A platform for peptidase detection based on text mining techniques and support vector machines". 449-459. 2013. 10.1007/978-94-007-4722-7_42 Morgado, L.; Pereira, C.; Veríssimo, P.; Dourado, A.. "Efficient discriminative models for proteomics with simple and optimized features". 89-98. 2013. 10.1007/978-94-007-4722-7_9 Oliveira, J.; Correia, D.; Pereira, C.; Veríssimo, P.; Dourado, A.. "A tool for biomedical – documents classification using support vector machines". 407-416. 2013. 10.1007/978-94-007-4722-7_38 Morgado, L.; Pereira, C.; Veríssimo, P.; Dourado, A.. "Peptidase detection and classification using enhanced kernel methods with feature selection". 2011. 10.1007/978-3-642-19914-1_4 Faro, C.; Ramalho-Santos, M.; Veríssimo, P.; Pissarra, J.; Frazão, C.; Costa, J.; Lin, X.-L.; Tang, J.; Pires, E.. "Structural and functional aspects of cardosins". 1998. Bento, I.; Coelho, R.; Frazão, C.; Costa, J.; Faro, C.; Veríssimo, P.; Pires, E.; et al. "Crystallisation, structure solution, and initial refinement of plant cardosin-A". 1998. Veríssimo, P.; Ramalho-Santos, M.; Faro, C.; Pires, E.. "A comparative study on the aspartic proteinases from different species of Cynara". 1998.
Journal article	Bruno Casimiro; Inês Mota; Paula Veríssimo; Jorge Canhoto; Sandra Correia. "Enhancing the Production of Hydrolytic Enzymes in Elicited Tamarillo (Solanum betaceum Cav.) Cell Suspension Cultures". Plants (2023): https://doi.org/10.3390/plants12010190. 10.3390/plants12010190 Paula Verissimo; João Martins; Paula Veríssimo; Jorge Canhoto. "Isolation and identification of Arbutus unedo L. fungi endophytes and biological control of Phytophthora cinnamomi in vitro". Protoplasma 259 3 (2022): 659-677. http://dx.doi.org/10.1007/s00709-021-01686-2. 10.1007/s00709-021-01686-2 Elisabete Ferreira; Zaida L. Almeida; Pedro F. Cruz; Marta Silva e Sousa; Paula Veríssimo; Rui M. M. Brito. "Searching for the Best Transthyretin Aggregation Protocol to Study Amyloid Fibril Disruption". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms23010391. 10.3390/ijms23010391 Gaspar, Ricardo; de Matos, Mafalda Ramos; Cortes, Luísa; Nunes-Correia, Isabel; Todo-Bom, Ana; Pires, Euclides; Veríssimo, Paula. "Pollen Proteases Play Multiple Roles in Allergic Disorders". International Journal of Molecular Sciences 21 10 (2020): 3578. http://dx.doi.org/10.3390/ijms21103578. 10.3390/ijms21103578 Barcia, Cristina; Coelho, Ana Sofia; Barberis, Sonia; Veríssimo, Paula. "Acaciain peptidase : The first South American pollen peptidase potentially involved in respiratory allergy". Biotechnology and Applied Biochemistry 67 2 (2019): 224-233. http://dx.doi.org/10.1002/bab.1837. 10.1002/bab.1837 Correia, Sandra; Alhinho, Ana T.; Casimiro, Bruno; Miguel, Célia M.; Oliveira, Margarida; Veríssimo, Paula; Canhoto, Jorge; et al. "NEP-TC a rRNA methyltransferase involved on somatic embryogenesis of tamarillo (Solanum betaceum cav.)". Frontiers in Plant Science 10 (2019): http://hdl.handle.net/10362/92155. https://doi.org/10.3389/fpls.2019.00438 Colombo, M.L.; Fernández, A.; Cimino, C.V.; Liggieri, C.; Bruno, M.; Faro, C.; Veríssimo, P.C.; Vairo-Cavalli, S.. "Miniature cheeses made with blends of chymosin and a vegetable rennet from flowers of Silybum marianum: Enzymatic characterization of the flower-coagulant peptidase". Food Chemistry 266 (2018): 223-231. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048117086&partnerID=MN8TOARS. 10.1016/j.foodchem.2018.06.007 Alves, A.; Caeiro, A.; Correia, S.I.; Veríssimo, P.; Canhoto, J.. "Establishment and biochemical characterization of tamarillo (Solanum betaceum Cav.) embryogenic cell suspension cultures". In Vitro Cellular and Developmental Biology - Plant 53 6 (2017): 606-618. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032991015&partnerID=MN8TOARS. 10.1007/s11627-017-9864-z Correia SI; Alves AC; Veríssimo P; Canhoto JM. "Somatic Embryogenesis in Broad-Leaf Woody Plants: What We Can Learn from Proteomics.". Methods in molecular biology (Clifton, N.J.) (2016): http://europepmc.org/abstract/med/26619861. 10.1007/978-1-4939-3061-6_6 Azul, A.M.; Nunes, J.; Ferreira, I.; Coelho, A.S.; Veríssimo, P.; Trovão, J.; Campos, A.; Castro, P.; Freitas, H.. "Valuing native ectomycorrhizal fungi as a mediterranean forestry component for sustainable and innovative solutions1". Botany 92 2 (2014): 161-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893861095&partnerID=MN8TOARS. 10.1139/cjb-2013-0170 Paiva, Gabriel; Proença, Diogo Neves; Francisco, Romeu; Verissimo, Paula; Santos, Susana S.; Fonseca, Luís; Abrantes, Isabel M. O.; Morais, Paula V.. "Nematicidal Bacteria Associated to Pinewood Nematode Produce Extracellular Proteases". PLoS ONE 8 11 (2013): e79705. http://dx.doi.org/10.1371/journal.pone.0079705. 10.1371/journal.pone.0079705 Lufrano, D.; Faro, R.; Castanheira, P.; Parisi, G.; Veríssimo, P.; Vairo-Cavalli, S.; Simões, I.; Faro, C.. "Molecular cloning and characterization of procirsin, an active aspartic protease precursor from Cirsium vulgare (Asteraceae)". Phytochemistry 81 (2012): 7-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864746972&partnerID=MN8TOARS. 10.1016/j.phytochem.2012.05.028 Correia, S.; Vinhas, R.; Manadas, B.; Lourenço, A.S.; Veríssimo, P.; Canhoto, J.M.. "Comparative proteomic analysis of auxin-induced embryogenic and nonembryogenic tissues of the solanaceous tree c yphomandra betacea (tamarillo)". Journal of Proteome Research 11 3 (2012): 1666-1675. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857806173&partnerID=MN8TOARS. 10.1021/pr200856w Vinhas, R.; Cortes, L.; Cardoso, I.; Mendes, V.M.; Manadas, B.; Todo-Bom, A.; Pires, E.; Veríssimo, P.. "Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides". Allergy: European Journal of Allergy and Clinical Immunology 66 8 (2011): 1088-1098. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960015037&partnerID=MN8TOARS. 10.1111/j.1398-9995.2011.02598.x Morgado, L.; Pereira, C.; Veríssimo, P.; Dourado, A.. "Modelling proteolytic enzymes with Support Vector Machines.". Journal of integrative bioinformatics 8 3 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84855526191&partnerID=MN8TOARS. 10.2390/biecoll-jib-2011-170 Toubarro, D.; Lucena-Robles, M.; Nascimento, G.; Santos, R.; Montiel, R.; Veríssimo, P.; Pires, E.; et al. "Serine protease-mediated host invasion by the parasitic nematode Steinernema carpocapsae". Journal of Biological Chemistry 285 40 (2010): 30666-30675. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957259709&partnerID=MN8TOARS. 10.1074/jbc.M110.129346 Hansen, Daiane; Macedo-Ribeiro, Sandra; Veríssimo, Paula; Yoo Im, Sonia; Sampaio, Misako Uemura; Oliva, Maria Luiza Vilela; Hansen, D.; et al. "Crystal structure of a novel cysteinless plant Kunitz-type protease inhibitor". Biochemical and Biophysical Research Communications 360 4 (2007): 735-740. http://hdl.handle.net/10316/3858. 10.1016/j.bbrc.2007.06.144 Cortes, L.; Carvalho, A.L.; Todo-Bom, A.; Faro, C.; Pires, E.; Veríssimo, P.. "Purification of a novel aminopeptidase from the pollen of Parietaria judaica that alters epithelial integrity and degrades neuropeptides". Journal of Allergy and Clinical Immunology 118 4 (2006): 878-884. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749349447&partnerID=MN8TOARS. 10.1016/j.jaci.2006.05.029 Guevara, M.G.; Almeida, C.; Mendieta, J.R.; Faro, C.J.; Veríssimo, P.; Pires, E.V.; Daleo, G.R.. "Molecular cloning of a potato leaf cDNA encoding an aspartic protease (StAsp) and its expression after P. infestans infection". Plant Physiology and Biochemistry 43 9 (2005): 882-889. http://www.scopus.com/inward/record.url?eid=2-s2.0-28444471988&partnerID=MN8TOARS. 10.1016/j.plaphy.2005.07.004 Guevara, M.G.; Veríssimo, P.; Pires, E.; Faro, C.; Daleo, G.R.. "Potato aspartic proteases: Induction, antimicrobial activity and substrate specificity". Journal of Plant Pathology 86 3 (2004): 233-238. http://www.scopus.com/inward/record.url?eid=2-s2.0-12144266872&partnerID=MN8TOARS. Vieira, M.; Pissarra, J.; Veríssimo, P.; Castanheira, P.; Costa, Y.; Pires, E.; Faro, C.; et al. "Molecular cloning and characterization of cDNA encoding cardosin B, an aspartic proteinase accumulating extracellularly in the transmitting tissue of Cynara cardunculus L.". Plant Molecular Biology 45 5 (2001): 529-539. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034982756&partnerID=MN8TOARS. 10.1023/A:1010675015318 Frazão, C.; Bento, I.; Costa, J.; Soares, C.M.; Veríssimo, P.; Faro, C.; Pires, E.; Cooper, J.; Carrondo, M.A.. "Crystal structure of cardosin A, a glycosylated and Arg-Gly-Asp- containing aspartic proteinase from the flowers of Cynara cardunculus L.". Journal of Biological Chemistry 274 39 (1999): 27694-27701. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033600810&partnerID=MN8TOARS. 10.1074/jbc.274.39.27694 Faro, C.; Ramalho-Santos, M.; Vieira, M.; Mendes, A.; Simões, I.; Andrade, R.; Veríssimo, P.; et al. "Cloning and characterization of cDNA encoding cardosin A, an RGD- containing plant aspartic proteinase". Journal of Biological Chemistry 274 40 (1999): 28724-28729. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033214046&partnerID=MN8TOARS. 10.1074/jbc.274.40.28724 Ramalho-Santos, M.; Verissimo, P.; Cortes, L.; Samyn, B.; Beeumen, J.V.; Pires, E.; Faro, C.; et al. "Identification and proteolytic processing of procardosin A". European Journal of Biochemistry 255 1 (1998): 133-138. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032127477&partnerID=MN8TOARS. 10.1046/j.1432-1327.1998.2550133.x Bento I; Coelho R; Frazão C; Costa J; Faro C; Veríssimo P; Pires E; et al. "Crystallisation, structure solution, and initial refinement of plant cardosin-A.". Advances in experimental medicine and biology (1998): http://europepmc.org/abstract/med/9580380. Veríssimo P; Ramalho-Santos M; Faro C; Pires E. "A comparative study on the aspartic proteinases from different species of Cynara.". Advances in experimental medicine and biology (1998): http://europepmc.org/abstract/med/9561253. Faro C; Ramalho-Santos M; Veríssimo P; Pissarra J; Frazão C; Costa J; Lin XL; Tang J; Pires E. "Structural and functional aspects of cardosins.". Advances in experimental medicine and biology (1998): http://europepmc.org/abstract/med/9580379. Costa J; Ashford DA; Nimtz M; Bento I; Frazäo C; Esteves CL; Faro CJ; et al. "The glycosylation of the aspartic proteinases from barley (Hordeum vulgare L.) and cardoon (Cynara cardunculus L.).". European journal of biochemistry 243 3 (1997): 695-700. http://europepmc.org/abstract/med/9057834. 10.1111/j.1432-1033.1997.t01-1-00695.x Ramalho-Santos, M.; Pissarra, J.; Veríssimo, P.; Pereira, S.; Salema, R.; Pires, E.; Faro, C.J.. "Cardosin A, an abundant aspartic proteinase, accumulates in protein storage vacuoles in the stigmatic papillae of Cynara cardunculus L.". Planta 203 2 (1997): 204-212. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031257393&partnerID=MN8TOARS. 10.1007/s004250050183 Verissimo, P.; Cliveira; Andrade, I.L.; Faro, C.; Pires, E.. "A pistil-specific aspartic proteinase from cynara humilis: purification, characterization and edna cloning". FASEB Journal 11 9 (1997): http://www.scopus.com/inward/record.url?eid=2-s2.0-33750255079&partnerID=MN8TOARS. Duarte EP; Baltazar G; Veríssimo P; Carvalho AP. "Release of catecholamines and enkephalin peptides induced by reversal of the Na(+)-Ca2+ exchanger in chromaffin cells.". Annals of the New York Academy of Sciences (1996): http://europepmc.org/abstract/med/8659852. 10.1111/j.1749-6632.1996.tb44810.x Veríssimo, Paula; Faro, Carlos; Moir, Arthur J. G.; Lin, Yingzhang; Tang, Jordan; Pires, Euclides. "Purification, Characterization and Partial Amino Acid Sequencing of Two New Aspartic Proteinases from Fresh Flowers of Cynara cardunculus L.". (1996): http://hdl.handle.net/10316/8139. Veríssimo, P.; Faro, C.; Moir, A.J.G.; Lin, Y.; Tang, J.; Pires, E.. "Purification, characterization and partial amino acid sequencing of two new aspartic proteinases from fresh flowers of Cynara cardunculus L.". European Journal of Biochemistry 235 3 (1996): 762-768. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030060726&partnerID=MN8TOARS. 10.1111/j.1432-1033.1996.00762.x Ramalho-Santos, M.; Veríssimo, P.; Faro, C.; Pires, E.. "Action on bovine a(s1)-casein of cardosins A and B, aspartic proteinases from the flowers of the cardoon Cynara cardunculus L.". Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology 1297 1 (1996): 83-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030582404&partnerID=MN8TOARS. 10.1016/0167-4838(96)00103-3 Verissimo, P.; Esteves, C.; Faro, C.; Pires, E.. "The vegetable rennet of Cynara cardunculus L. contains two proteinases with chymosin and pepsin-like specificities". Biotechnology Letters 17 6 (1995): 621-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029018457&partnerID=MN8TOARS. 10.1007/BF00129389 Faro C; Verissimo P; Lin Y; Tang J; Pires E; Faro, C.; Verissimo, P.; et al. "Cardosin A and B, aspartic proteases from the flowers of cardoon.". Advances in experimental medicine and biology 362 (1995): 373-377. http://europepmc.org/abstract/med/8540346.
Thesis / Dissertation	Pires, Paula Cristina Veríssimo. "Cardosina A e Cardosina B : proteases aspárticas de Cynara cardunculus L : purificação, caracterização e sequência parcial de aminoácidos". PhD, 1996. http://hdl.handle.net/10316/1770.

Other distinction

2004	European Regional Innovation Award