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Identification

Personal identification

Full name
Sara Maria Lopes Marques

Citation names

  • Marques, Sara

Author identifiers

Ciência ID
BB17-0F5D-A4FB
ORCID iD
0000-0001-6784-5612
Education
Degree Classification
1998/12/10
Concluded
 Bioquímica (Licenciatura)
Major in Bioquímica Aplicada
Universidade do Porto Faculdade de Ciências, Portugal
"Purificação da p43 e estudos de efeitos imunológicos induzidos pela p36, proteínas imunomodeladoras de origem microbiana" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2014/11/01 - Current Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2006 - 2016 Researcher (Research) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
1999/02 - 2006 Researcher (Research) Instituto Gulbenkian de Ciência, Portugal
Instituto Gulbenkian de Ciência, Portugal
1998 - 1999/02 Research Trainee (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Projects

Contract

Designation Funders
2018/09/01 - 2021/08/31 Role of CCBE1 during coronary vasculature development and neo-angiogenesis upon myocardial infarction, through stimulation of VEGF-C signaling.
PTDC/MEC-CAR/29590/2017
Universidade Nova de Lisboa, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016/05/01 - 2019/10/31 Control of cardiomyocyte proliferation in disease and regenerative medicine
PTDC/BIM-MED/3363/2014
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

iNOVA4Health, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015/01/01 - 2018/03/31 CardioRegen: Integrative studies from the embryo to Scalable Multipronged Generation of hESC-derived Myocardial progenitors for heart repair
HMSP-ICT/0039/2013
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Role of the novel gene Ccbe in heart induction and organogenesis
PTDC/SAU-BID/114902/2009
Universidade do Algarve, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/01/01 - 2012/12/31 Study of heart formation at molecular terms to understand congenital heart malformations
PTDC/SAU-GMG/101890/2008
Universidade do Algarve, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/05/01 - 2010/12/31 Genetic and biochemical control of Cerl-2 activity during early development
PTDC/SAU-OBD/69928/2006
Universidade do Algarve, Portugal

Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal

Fundação Calouste Gulbenkian, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/11/15 - 2010/11/14 Study of the role of vertebrate ADTK1, a novel dual-specificity Ser/Thr/Tyr kinase gene family
PTDC/BIA-BCM/69912/2006
Universidade do Algarve, Portugal

Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal

Fundação Calouste Gulbenkian, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2001/01/01 - 2003/12/31 Genetic ontrol of vertebrate development: The role of the cerberus-like family of secreted inhibitors and Anterior Visceral Endoderm signalling
POCTI/BCI/34350/2000
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book review
  1. Belo, José A; Marques, Sara; Inácio, José M; Centro de Estudos de Doenças Crónicas (CEDOC); NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM). "The Role of Cerl2 in the Establishment of Left-Right Asymmetries during Axis Formation and Heart Development". http://hdl.handle.net/10362/40540.
    https://doi.org/10.3390/jcdd4040023
Conference paper
  1. Inacio, Jose M.; Marques, Sara; Belo, José A.. "Functional analysis of the mouse Nodal antagonist, Cerl2, during left-right axis formation". 2010.
    10.1016/j.ydbio.2010.05.209
  2. Becker, Jorg D.; Steinbeisser, Herbert; Belo, A.; Silva, Ana C.; Vitorino, Marta; Filipa, Mário; Marques, Sara. "Study of Xenopus orthologs of novel genes expressed in the mouse AVE". 2007.
    10.1016/j.ydbio.2007.03.607
Journal article
  1. Marques, Sara. "CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart". Developmental Dynamics (2018): http://dx.doi.org/10.1002/dvdy.24670.
    10.1002/dvdy.24670
  2. Marques, Sara. "The Role of Cerl2 in the Establishment of Left-Right Asymmetries during Axis Formation and Heart Development". Journal of Cardiovascular Development and Disease (2017): http://www.mdpi.com/2308-3425/4/4/23.
    10.3390/jcdd4040023
  3. Araújo AC; Marques S; Belo JA. "Targeted inactivation of Cerberus like-2 leads to left ventricular cardiac hyperplasia and systolic dysfunction in the mouse.". (2014): http://europepmc.org/abstract/med/25033293.
    10.1371/journal.pone.0102716
  4. Inácio JM; Marques S; Nakamura T; Shinohara K; Meno C; Hamada H; Belo JA. "The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node.". (2013): http://europepmc.org/abstract/med/23544137.
    10.1371/journal.pone.0060406
  5. Gonçalves L; Filipe M; Marques S; Salgueiro AM; Becker JD; Belo JA. "Identification and functional analysis of novel genes expressed in the Anterior Visceral Endoderm.". (2011): http://europepmc.org/abstract/med/21553379.
    10.1387/ijdb.103273lg
  6. Goncalves, Lisa; Filipe, Mario; Marques, Sara; Salgueiro, Ana-Marisa; Becker, Jorg D.; Belo, Jose Antonio. "Identification and functional analysis of novel genes expressed in the Anterior Visceral Endoderm". (2011): http://hdl.handle.net/10400.7/692.
    10.1387/ijdb.103273lg
  7. Oki S; Kitajima K; Marques S; Belo JA; Yokoyama T; Hamada H; Meno C. "Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.". (2009): http://europepmc.org/abstract/med/19906859.
    10.1242/dev.039305
  8. Belo JA; Silva AC; Borges AC; Filipe M; Bento M; Gonçalves L; Vitorino M; et al. "Generating asymmetries in the early vertebrate embryo: the role of the Cerberus-like family.". (2009): http://europepmc.org/abstract/med/19247954.
    10.1387/ijdb.072297jb
  9. Echevarria D; Martinez S; Marques S; Lucas-Teixeira V; Belo JA. "Mkp3 is a negative feedback modulator of Fgf8 signaling in the mammalian isthmic organizer.". (2005): http://europepmc.org/abstract/med/15572144.
    10.1016/j.ydbio.2004.09.011
  10. Marques S; Borges AC; Silva AC; Freitas S; Cordenonsi M; Belo JA. "The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis.". (2004): http://europepmc.org/abstract/med/15466485.
    10.1101/gad.306504
  11. Borges AC; Marques S; Belo JA. "Goosecoid and cerberus-like do not interact during mouse embryogenesis.". (2002): http://europepmc.org/abstract/med/11934155.
  12. Borges AC; Marques S; Belo JA. "The BMP antagonists cerberus-like and noggin do not interact during mouse forebrain development.". (2001): http://europepmc.org/abstract/med/11330864.
  13. Belo JA; Bachiller D; Agius E; Kemp C; Borges AC; Marques S; Piccolo S; De Robertis EM. "Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development.". (2000): http://europepmc.org/abstract/med/10748465.
    10.1002/(SICI)1526-968X(200004)26:4<265::AID-GENE80>3.3.CO;2-W
Activities

Association member

Society Organization name Role
2017 - Current CONGENTO - Consortium for Genetically Tractable Organisms Representative of the Rodent Animal Facility as Facility Manager and Animal Welfare Officer

Committee member

Activity description
Role 		Institution / Organization
2019 - Current Animal Welfare Body (ORBEA)
Member
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2016 - Current Biosafety and Good Laboratory Practices Committee, Nova Medical School
Member
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 - 2019 Installation Committee of the Animal Welfare Body, Nova Medical School
Member
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Distinctions

Award

2005 Prémio SPGH - Portuguese first author of the best paper published in the previous year in the field of Human Genetics
Sociedade Portuguesa de Genética Humana, Portugal
2001 Best Communication (poster)
Scientific committee of the III Congress of the Spanish Society of Developmental Biology, Spain