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Identification

Personal identification

Full name
Maria José da Chão Alves

Citation names

  • Alves, Maria
  • Alves, M.J.

Author identifiers

Ciência ID
BB1D-869F-9EE3
ORCID iD
0000-0002-1864-2277

Telephones

Mobile phone
  • 916295655 (Personal)

Addresses

  • Rua Do Caires, nº 302, 8º Dto, 4700-207, Braga, Braga, Portugal (Personal)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences
Education
Degree Classification
1996/09/12 - 1997/09/30
Concluded
 Bolsa pós-doc (Pós-doutoramento)
University of Liverpool Department of Chemistry, United Kingdom
1985/10/28 - 1990/06/11
Concluded
 Doutoramento em Ciências (Doutoramento)
Major in Química
Universidade do Minho, Portugal
"O diaminomaleonitrilo na síntese de purinas e compostos relacionados" (THESIS/DISSERTATION)
 Distinção e Louvor
1983/10/03 - 1985/10/27
Concluded
 Provas de Capacidade Científica e Aptidão Pedagógica (Outros)
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Muito bom
1975/10/02 - 1980/07/30
Concluded
 Ciências Farmacêuticas/Farmácia Industrial (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
 16
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
1999/03/22 - Current Associate Professor (University Teacher) Universidade do Minho, Portugal
Universidade do Minho Centro de Química, Portugal
1990/06/11 - 1999/03/21 Assistant Professor (University Teacher) Universidade do Minho, Portugal
1985/10/29 - 1990/06/10 Assistant (University Teacher) Universidade do Minho Centro de Química, Portugal
1982/01/05 - 1985/10/28 Trainee Assistant (University Teacher) Universidade de Lisboa, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Contract

Designation Funders
2012/05 - 2015/10 Estratégias Concisas e Estereoseletivas de Síntese de Aza-açúcares. Estudos Teóricos e Biológicos dos Produtos.
PTDC/QEQ-MED/1671/2012
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2006 - 2010 Estratégia Comum de Síntese de Aza-açúcares e Nucleósidos Modificados. Avaliação Biológica dos Produtos.
PTDC/QUI/67407/2006
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001/01 - 2005/07 Síntese e Reactividade de 2H-Azirinas Electrofílicas
POCTI/QUI/32723/2000
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
1992/10/10 - 1995/10/10 Amidinas Derivadas do Diaminomaleonitrilo na Síntese de Compostos Heterocíclicos
PBIC/C/CEN/1028/92
Principal investigator
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Journal article
  1. Akhundova, Fidan N.; Kurbanova, Malahat M.; Huseynzada, Alakbar E.; Alves, Maria J.; Sujayev, Afsun R.. "Synthesis and Bioactivity of New Analogue of Bicyclic 1-Azafagomine". ChemistrySelect 4 45 (2019): 13384-13387. http://dx.doi.org/10.1002/slct.201903190.
    10.1002/slct.201903190
  2. Alves, Maria. "A Short Synthesis of (2S,3S,4R)-Dihydroxyhomoprolines from d-Erythrose-Derived 5,6-Dihydro-2H-pyran-2-one". Synthesis (2019): http://dx.doi.org/10.1055/s-0037-1611479.
    10.1055/s-0037-1611479
  3. David S. Freitas; Cristina E. A. Sousa; Joana Parente; Artem Drogalin; António Gil Fortes; Nuno M. F. S. A. Cerqueira; Maria J. Alves. "(3S,4R)-3,4-Dihydroxy-N-alkyl-l-homoprolines: synthesis and computational mechanistic studies". Organic & Biomolecular Chemistry (2019): https://doi.org/10.1039/C9OB02141H.
    10.1039/C9OB02141H
  4. Juliana F. Rocha; David S. Freitas; Jennifer Noro; Carla S. Silva Teixeira; Cristina E. A. Sousa; Maria J. Alves; Nuno M. F. S. A. Cerqueira. "Total Stereoselective Michael Addition of N- and S- Nucleophiles to a d-Erythrosyl 1,5-Lactone Derivative. Experimental and Theoretical Studies Devoted to the Synthesis of 2,6-Dideoxy-4-functionalized-d-ribono-hexono-1,4-lactone". The Journal of Organic Chemistry (2018): https://doi.org/10.1021/acs.joc.8b00769.
    10.1021/acs.joc.8b00769
  5. Babar, Ayesha; Yar, Muhammad; Tarazi, Hamadeh; Duarte, Vera; Alshammari, Mohammed B.; Gilani, Mazhar Amjad; Iqbal, Haffsah; et al. "Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates". Medicinal Chemistry Research 26 12 (2017): 3247-3261. http://dx.doi.org/10.1007/s00044-017-2018-3.
    Published • 10.1007/s00044-017-2018-3
  6. Cristina E. A. Sousa; António M. P. Ribeiro; António Gil Fortes; Nuno M. F. S. A. Cerqueira; Maria J. Alves. "Total Facial Discrimination of 1,3-Dipolar Cycloadditions in a d-Erythrose 1,3-Dioxane Template: Computational Studies of a Concerted Mechanism". The Journal of Organic Chemistry 82 2 (2017): 982-991. https://doi.org/10.1021/acs.joc.6b02518.
    10.1021/acs.joc.6b02518
  7. Kuzniarska-Biernacka, I.; Lisinska-Czekaj, A.; Czekaj, D.; Alves, M. José; Fonseca, A. Mauricio; Neves, I. Correia. "Styrene Epoxidation Over Heterogeneous Manganese(III) Complexes". Archives of Metallurgy and Materials 61 3 (2016): 1477-1482. http://dx.doi.org/10.1515/amm-2016-0242.
    10.1515/amm-2016-0242
  8. Alves, Maria. "Total Facial Selectivity of a D-Erythrosyl Aromatic Imine in [4p+2p] Cycloadditions; Synthesis of 2-Alkylpolyol 1,2,3,4-Tetrahydroquinolines". Organic & Biomolecular Chemistry (2016):
    10.1039/c5ob02594j
  9. Alves, Maria. "Exploiting the Antiparasitic Activity of Naphthalimides Derivatives". Int. J. Chem. Pharm. Sci 4 1 (2016): 19-23.
    Published
  10. J, Noro; J, Maciel. "Evaluation of New Naphthalimides as Potential Anticancer Agents against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT- 15 Cell Lines". Organic Chemistry: Current Research 04 03 (2015): http://dx.doi.org/10.4172/2161-0401.1000144.
    10.4172/2161-0401.1000144
  11. Riaz, Sadaf; Khan, Islam Ullah; Yar, Muhammad; Ashraf, Muhammad; Rehman, Tanzeel Ur; Shaukat, Ayesha; Jamal, Syed Babar; Duarte, Vera C.M.; Alves, Maria J.. "Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as a- and ß-glucosidase inhibitors". Bioorganic Chemistry 57 (2014): 148-154. http://dx.doi.org/10.1016/j.bioorg.2014.10.007.
    Published • 10.1016/j.bioorg.2014.10.007
  12. Kuzniarska-Biernacka, I.; Parpot, P.; Oliveira, C.; Silva, A. R.; Alves, M. J.; Fonseca, A. M.; Neves, I. C.. "Norbornene Oxidation by Chiral Complexes Encapsulated in NaY Zeolite". The Journal of Physical Chemistry C 118 33 (2014): 19042-19050. http://dx.doi.org/10.1021/jp5031812.
    Published • 10.1021/jp5031812
  13. Alves, Maria. "Enantioselective Diels-Alder Cycloadditions in the Synthesis of Two Enantiomeric Sets of Chiral Polihydroxylated Pipecolic Acid Derivatives". Synlett (2014):
    10.1055/s-0034-1378227
  14. Alves, Maria. "Synthesis and evaluation of a-, ß-glucosidase inhibition of 1-N-carboxamide-1-azafagomines and 5-epi-1-azafagomines". Carbohydrate Research (2014):
    10.1016/j.carres.2014.06.015
  15. Alves, Maria. "Synthesis of Iminosugars from Tetroses". Curr. Org. Synth. (2014):
    10.2174/15701794113106660074
  16. RUIZ-BLANCO, YASSER B; ALVES, MARIA J; RODRÍGUEZ-BORGES, JOSÉ E; MOLINA, REINALDO. "STUDY BASED ON ELECTRONIC DESCRIPTORS OF THE DIASTEREOSELECTIVE AZA-DIELS-ALDER CYCLOADDITION OF [(1R)-10-(N,N-DIETHYLSULFAMOYL)ISOBORNYL] 2H-AZIRINE-3-CARBOXYLATE TO E,E-1,4-DIACETOXY-1,3-BUTADIENE". Journal of the Chilean Chemical Society 58 4 (2013): 2243-2247. http://dx.doi.org/10.4067/s0717-97072013000400074.
    Published • 10.4067/s0717-97072013000400074
  17. Duarte, V.C.M.; Faustino, H.; Alves, M.J.; Gil Fortes, A.; Micaelo, N.. "Asymmetric Diels-Alder cycloadditions of d-erythrose 1,3-butadienes to achiral t-butyl 2H-azirine 3-carboxylate". Tetrahedron Asymmetry 24 18 (2013): 1063-1068. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884583990&partnerID=MN8TOARS.
    10.1016/j.tetasy.2013.05.015
  18. García-Mera, X.; Alves, M.J.; Goth, A.; Do Vale, M.L.; Rodríguez-Borges, J.E.. "Highly stereoselective cycloadditions of Danishefsky's diene to (-)-8-phenylmenthyl and (+)-8-phenylneomenthyl glyoxylate N-phenylethylimines". Tetrahedron 69 14 (2013): 2909-2919. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874645262&partnerID=MN8TOARS.
    10.1016/j.tet.2013.02.027
  19. Salgueiro, D.A.L.; Sousa, C.E.A.; Fortes, A.G.; Alves, M.J.. "Diels-alder cycloaddition in the synthesis of 1-azafagomine, analogs, and derivatives as glycosidase inhibitors". Mini-Reviews in Medicinal Chemistry 12 14 (2012): 1465-1476. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873105709&partnerID=MN8TOARS.
    10.2174/138955712803832663
  20. Salgueiro, D.A.L.; Duarte, V.M.; Sousa, C.E.A.; Alves, M.J.; Gil Fortes, A.. "Diastereoselectivity in diels-alder cycloadditions of erythrose benzylidene-acetal 1,3-butadienes with maleimides". Synlett 23 12 (2012): 1765-1768. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862627344&partnerID=MN8TOARS.
    10.1055/s-0031-1289785
  21. Alves, M.J.; Costa, F.T.; Duarte, V.C.M.; Fortes, A.G.; Martins, J.A.; Micaelo, N.M.. "Advances in the synthesis of homochiral (-)-1-azafagomine and (+)-5-epi-1-azafagomine. 1-N-phenyl carboxamide derivatives of both enantiomers of 1-azafagomine: Leads for the synthesis of active a-glycosidase inhibitors.". Journal of Organic Chemistry 76 23 (2011): 9584-9592. http://www.scopus.com/inward/record.url?eid=2-s2.0-82255170789&partnerID=MN8TOARS.
    10.1021/jo201486q
  22. García-Mera, X.; Rodríguez-Borges, J.E.; Vale, M.L.C.; Alves, M.J.. "Highly diastereoselective synthesis of 2-azabicyclo[2.2.1]hept-5-ene derivatives: Bronsted acid catalyzed aza-Diels-Alder reaction between cyclopentadiene and imino-acetates with two chiral auxiliaries". Tetrahedron 67 37 (2011): 7162-7172. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051699686&partnerID=MN8TOARS.
    10.1016/j.tet.2011.06.097
  23. Alves, M.J.; Duarte, V.C.M.; Faustino, H.; Gil Fortes, A.. "Diastereo-controlled DielsAlder cycloadditions of erythrose benzylidene-acetal 1,3-butadienes by 4-substituted-1,2,4-triazoline-3,5-dione: Evidence for the stereoelectronic effects on the dienes". Tetrahedron Asymmetry 21 15 (2010): 1817-1820. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957563959&partnerID=MN8TOARS.
    10.1016/j.tetasy.2010.05.001
  24. Alves, M.J.; Lemos, A.; Rodriguez-Borges, J.E.; Garcia-Mera, X.; Fortes, A.G.. "Ethyl 2-(diisopropoxyphosphoryl)-2h-azirine-3-carboxylate: Reactions with nucleophilic 1,3-dienes". Synthesis 19 (2009): 3263-3266. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350456477&partnerID=MN8TOARS.
    10.1055/s-0029-1216945
  25. Alves, M.J.; Costa, C.; Durães, M.M.. "Diastereoselective Diels-Alder cycloaddition of [(1R)-10-(N,N-diethylsulfamoyl)isobornyl] 2H-azirine to nucleophilic 1,4-disubstituted 1,3-dienes". Tetrahedron Asymmetry 20 12 (2009): 1378-1382. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649664199&partnerID=MN8TOARS.
    10.1016/j.tetasy.2009.05.035
  26. Rodriguez-Borges, J.E.; Vale, M.L.C.; Aguiar, F.R.; Alves, M.J.; García-Mera, X.. "Synthesis of polyhydroxylated pyrrolidines and aziridinopyrrolidines from [4p+2p] cycloadducts of cyclopentadiene and imines/2H-azirines". Synthesis 6 (2008): 971-977. http://www.scopus.com/inward/record.url?eid=2-s2.0-41349123253&partnerID=MN8TOARS.
    10.1055/s-2008-1032196
  27. Alves, M.J.; Carvalho, M.A.; Carvalho, S.; Dias, A.M.; Fernandes, F.H.; Proença, M.F.. "A new approach to the synthesis of N,N-dialkyladenine derivatives". European Journal of Organic Chemistry 29 (2007): 4881-4887. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348953727&partnerID=MN8TOARS.
    10.1002/ejoc.200700416
  28. Alves, M.J.; Fortes, A.G.; Costa, F.T.; Duarte, V.C.M.. "Formation of pyridin-4(1H)-one versus 1H-azepin-4(7H)-one by treatment of 4-tert-butyldimethylsilyloxy-2-amino-1-aza-bicyclo[4.1.0]hept-3-enes with tetrabutylammonium fluoride". Tetrahedron 63 45 (2007): 11167-11173. http://www.scopus.com/inward/record.url?eid=2-s2.0-34648840828&partnerID=MN8TOARS.
    10.1016/j.tet.2007.08.007
  29. Alves, M.J.; Azoia, N.G.; Fortes, A.G.. "Regio- and stereo-selective aza-Diels-Alder reaction of ethyl glyoxylate 4-methoxyphenylimine with 1,3-dienes in the presence of BF3·Et2O. Evidence for a non-concerted mechanism". Tetrahedron 63 3 (2007): 727-734. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845322646&partnerID=MN8TOARS.
    10.1016/j.tet.2006.10.085
  30. Alves, M.J.; García-Mera, X.; Vale, M.L.C.; Santos, T.P.; Aguiar, F.R.; Rodríguez-Borges, J.E.. "Stereoselective synthesis of polyhydroxylated pyrrolidines: a route to novel 3,5-bis(hydroxymethyl)pyrrolidines from 2-azabicyclo[2.2.1]hept-5-enes". Tetrahedron Letters 47 43 (2006): 7595-7597. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748752613&partnerID=MN8TOARS.
    10.1016/j.tetlet.2006.08.077
  31. Alves, M.J.; Fortes, A.G.; Costa, F.T.. "Diels-Alder cycloaddition of electrophilic 2H-azirines with 3-(3-(tert-butyldimethylsilyloxy)buta-1,3-dienyl)oxazolidin-2-ones. Treatment of the cycloadducts under acidic conditions". Tetrahedron 62 13 (2006): 3095-3102. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644693780&partnerID=MN8TOARS.
    10.1016/j.tet.2006.01.035
  32. Alves, M.J.; Azoia, N.G.; Fortes, A.G.. "Synthesis of 1,3,8,8a-tetrahydro-3,8-epoxyazirino[1,2-b]isoquinolines and their reactions with oxygen nucleophiles". Heterocycles 65 6 (2005): 1329-1345. http://www.scopus.com/inward/record.url?eid=2-s2.0-31344461850&partnerID=MN8TOARS.
    10.3987/COM-05-10365
  33. Alves, M.J.; Fortes, A.G.; Lemos, A.; Martins, C.. "Ethyl 3-(2-pyridyl)-2H-azirine-2-carboxylate: Synthesis and reaction with dienes". Synthesis 4 (2005): 555-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-15444362226&partnerID=MN8TOARS.
    10.1055/s-2004-837296
  34. Alves, M.J.; Durães, M.M.; Fortes, A.G.. "Diels-Alder cycloaddition of 2-azadienes to methyl 2-(2,6-dichlorophenyl)- 2H-azirine-3-carboxylate in the synthesis of methyl 4-oxo-1,3-diazabicyclo[4.1. 0]heptane-6-carboxylates". Tetrahedron 60 31 (2004): 6541-6553. http://www.scopus.com/inward/record.url?eid=2-s2.0-4143055091&partnerID=MN8TOARS.
    10.1016/j.tet.2004.06.004
  35. Alves, M.J.; Fortes, G.; Guimarães, E.; Lemos, A.. "Intermolecular alkyl radical addition to methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate". Synlett 10 (2003): 1403-1406. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042069858&partnerID=MN8TOARS.
  36. Alves, M.J.; Fortes, A.G.; Gonçalves, L.F.. "Optically active aziridine esters by nucleophilic addition of nitrogen heterocycles to a chiral 2H-azirine-2-carboxylic ester". Tetrahedron Letters 44 33 (2003): 6277-6279. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042848821&partnerID=MN8TOARS.
    10.1016/S0040-4039(03)01531-4
  37. Alves, M.J.; Durães, M.M.; Fortes, A.G.. "Cycloaddition of methyl 2-(2,6-dichorophenyl)-2H-azirine-3-carboxylate to electron-rich 2-azadienes". Tetrahedron Letters 44 27 (2003): 5079-5082. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038180383&partnerID=MN8TOARS.
    10.1016/S0040-4039(03)01138-9
  38. Alves, Maria. "Stereoselective Cycloaddition of 1-Glucosyl-1,3-butadienes with t-Butyl 2H-Azirine-3-carboxylate, Glyoxylates and Imines". Tetrahedron Letters 44 (2003): 6561-6565.
    Published
  39. Álvares, Y.S.P.; Alves, M.J.; Azoia, N.G.; Bickley, J.F.; Gilchrist, T.L.. "Diastereoselective synthesis of aziridines from (1R)-10-(N,N-dialkylsulfamoyl)isobornyl 2H-azirine-3-carboxylates". Journal of the Chemical Society. Perkin Transactions 1 16 (2002): 1911-1919. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035982161&partnerID=MN8TOARS.
  40. Alves, M.J.; Azoia, N.G.; Bickley, J.F.; Fortes, A.G.; Gilchrist, T.L.; Mendonça, R.. "Diels-Alder reactions of alkyl 2H-azirine-3-carboxylates with furans". Journal of the Chemical Society. Perkin Transactions 1 22 (2001): 2969-2976. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034746876&partnerID=MN8TOARS.
  41. Alves, M.J.; Ferreira, P.M.T.; Maia, H.L.S.; Monteiro, L.S.; Gilchrist, T.L.. "Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester". Tetrahedron Letters 41 25 (2000): 4991-4995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034686275&partnerID=MN8TOARS.
  42. Alves, M.J.; Carvalho, M.A.; Proenca, M.F.J.R.P.; Booth, B.L.. "Reactivity studies of ethyl(Z)-N-(2-amino-1,2-dicyanovinyl) formimidate with carbonyl compounds in the presence of base". Journal of Heterocyclic Chemistry 37 5 (2000): 1041-1048. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033763068&partnerID=MN8TOARS.
  43. Alves, M.J.; Gilchrist, T.L.; Sousa, J.H.. "Reactions of methyl 2-aryl-2H-azirine-3-carboxylates with nucleophiles". Journal of the Chemical Society - Perkin Transactions 1 10 (1999): 1305-1310. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001324963&partnerID=MN8TOARS.
  44. Alves, M.J.; Carvalho, M.A.; Proença, M.F.J.R.P.; Booth, B.L.; Pritchard, R.G.; Alves, Maria. "Synthesis and mechanism of formation of novel 2,5-dihydro-2,5-diimino- 3,4-di[(n,n-dimethylamino)methylideneamino]pyrroles and 5-amino-3,4-di[(n,n- dimethylamino)methylideneamino]2h-2-iminopyrroles". Journal of Heterocyclic Chemistry 36 1 (1999): 193-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032903661&partnerID=MN8TOARS.
    Published
  45. Alves, M. José; Bickley, Jamie F; Gilchrist, Thomas L.. "Diastereoselectivity in the addition and cycloaddition reactions of a chiral ester of 2H-azirine-3-carboxylic acid". Journal of the Chemical Society, Perkin Transactions 1 11 (1999): 1399-1402. http://dx.doi.org/10.1039/a902182e.
    10.1039/a902182e
  46. Alves, M.J.; Gilchrist, T.L.. "Generation and diels-alder reactions of t-butyl 2H-azirine-3-carboxylate". Tetrahedron Letters 39 41 (1998): 7579-7582. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032497610&partnerID=MN8TOARS.
  47. Alves, M.J.; Gilchrist, T.L.. "Methyl 2-aryl-2H-azirine-3-carboxylates as dienophiles". Journal of the Chemical Society - Perkin Transactions 1 2 (1998): 299-303. http://www.scopus.com/inward/record.url?eid=2-s2.0-4143057898&partnerID=MN8TOARS.
  48. Alves, M.J.; Carvalho, M.A.; Proença, M.F.J.R.P.; Booth, B.L.; Pritcbard, R.G.. "Synthesis of 6-Cyanopurines and the Isolation and X-ray Structure of Novel 2H-Pyrroles". Journal of Heterocyclic Chemistry 34 3 (1997): 739-743. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542498824&partnerID=MN8TOARS.
  49. Alves, M.J.; Booth, B.L.; Carvalho, A.; Dias, A.M.; Pritchard, R.G.; Proença, M.F.J.R.P.. "X-Ray Structure of 4-[5-Amino-1-(4-tolyl)-1H-imidazol-4-yl]-5-imino-2,2-dimethyl-2,5-dihydrooxazole and the Synthesis of a Related N3-Acetyl Analogue". Journal of Chemical Research - Part S 5 (1996): 212-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-2742607225&partnerID=MN8TOARS.
  50. Alves, Maria. "A Tautomeric Pair of 2,2-Dimethyl-6-carbamoyl-9-phenyl-dihydropurine". Acta Crystallographica, Section C, Crystal Structure Communications (1995): 1467-1470.
  51. Alves, M.J.; Booth, B.L.; Carvalho, A.; Eastwood, P.R.; Nezhat, L.; Pritchard, R.G.; Proença, M.F.J.R.P.. "Synthesis of 9-aryl-6-carbamoyl-1,2-dihydropurines and a study of their tautomerism". Journal of the Chemical Society, Perkin Transactions 2 9 (1994): 1949-1956. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049073318&partnerID=MN8TOARS.
  52. Alves, M.J.; Fernanda, M.; Proenca, J.R.P.; Booth, B.L.. "Synthesis of 4- and 5-disubstituted 1-benzylimidazoles, important precursors of purine analogs". Journal of Heterocyclic Chemistry 31 2 (1994): 345-350. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028356397&partnerID=MN8TOARS.
  53. Alves, M.J.; Al-Duaij, O.Kh.; Booth, B.L.; Carvalho, A.; Eastwood, P.R.; Proença, M.F.J.R.P.. "Synthesis of 4-substituted 8-amino-4,5-dihydro-3H-pyrrolo[3,4-f]-1,3,5- triazepin-6-ones and 5-amino-2-aryl-4-(1-aryl-5-alkylideneaminoimidazol-4-yl)-1, 3-oxazoles". Journal of the Chemical Society, Perkin Transactions 1 24 (1994): 3571-3577. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049087721&partnerID=MN8TOARS.
  54. Alves, M.J.; Booth, B.L.; Eastwood, P.; Pritchard, R.; Proença, M.F.J.R.P.. "Novel 4-substituted 4,5-dihydro-3H-(8-amino-6-oxo)pyrrolo[3,4-f][1,3,5] triazepines from(Z)-N2-(2-amino-1,2-dicyano)formamidine and carbonyl compounds". Journal of the Chemical Society, Chemical Communications 10 (1993): 834-836. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049079010&partnerID=MN8TOARS.
    10.1039/C39930000834
  55. Alves, M.J.; Booth, B.L.; Freitas, A.P.; Proença, M.F.J.R.P.. "(Z)-N3-(2-Amino-1,2-dicyanovinyl)formamidrazone: A precursor in the synthesis of 1,5-diaminoimidazoles and 6-carbamoyl-1,2-dihydropurines". Journal of the Chemical Society, Perkin Transactions 1 7 (1992): 913-918. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049082680&partnerID=MN8TOARS.
  56. Alves, M.J.; Booth, B.L.; Proenç, M.F.J.R.P.. "Synthesis of 5-amino-4-(cyanoformimidoyl)-1H-imidazole: A reactive intermediate for the synthesis of 6-carbamoyl-1,2-dihydropurines and 6-carbamoylpurines". Journal of the Chemical Society, Perkin Transactions 1 6 (1990): 1705-1712. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049074462&partnerID=MN8TOARS.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2013/04/01 - 2020/01/25 Synthesis and Computational Studies of Iminosugar Type Products Obtained from D-Erythrose
Supervisor
 Doutoramento em Ciências, especialidade em Química (PhD)
Universidade do Minho Centro de Química, Portugal
2018/09/15 - 2019/12/06 Tentativas de Síntese de análogos de Immucilina H a partir de um derivado daD-eritrose
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2018/09/15 - 2019/12/04 Design and synthesis of swainsonine analogs from 2,4-benzilidene D-erythrose, assisted by theoretical studies
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2017/09/10 - 2018/12/05 Selectividade divergente de nucleófilos em iminas e d-lactonas derivadas de 2,4-benzilidene D-eritrose
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2016/09/14 - 2018/03/01 Síntese de pirrolidinas e delta-lactonas polihidroxiladas, obtidas a partir da D-eritrose com potencial atividade enzimática em glicosidases
Supervisor
 Mestrado em Química Medicinal
Universidade do Minho Centro de Química, Portugal
2016/09/10 - 2017/09/11 Computational mechanistic studies in the synthesis of polyhydroxylated lactones obtained from a D-erythrosyl 1,3-dioxane template
Co-supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2015/09/15 - 2017/03/11 Preparation and Application of Chitosan-based Nano/Microstructures for Antimicrobial Protection of Leather
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2014/09/10 - 2015/12/04 Synthesis of polyhydroxylated compounds from D-erythrose. Enzymatic inhibition studies
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2013/10/13 - 2014/10/09 “Síntese e Avaliação Biológica de Naftalimidas N-Funcionalizadas”, 12 setembro 2014.
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2009/09/20 - 2014/02/02 Synthesis of iminosugars through diasteo/enantioselective Diels-Alder cycloaddition
Co-supervisor
 Doutoramento em Ciências, especialidade em Química (PhD)
Universidade do Minho Centro de Química, Portugal
2012/10/08 - 2013/12/10 Síntese de derivados do ácido cinâmico. Testes biológicos em linhas celulares de cancro”. Início em Outubro de 2012, fim em Dezembro 2013. (co-orientação)
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Centro de Química, Portugal
2011/09 - 2013/09 Reações 1,3-Dipolares entre uma Lactone a,ß-Insaturada Contendo um Sintão de D-Eritrose, com Vários 1,3-Dipolos. Estudos de Seletividade.
Supervisor
 Mestrado em Química Medicinal (Master)
Universidade do Minho Departamento de Química, Portugal
2002/09/03 - 2009/05 Reacções de Aza-Diels-Alder dirigidas à síntese de piperidinas polihidroxiladas e tetrahidroquinolinas
Supervisor
 Doutoramento em Ciências, especialidade em Química (PhD)
Universidade do Minho Escola de Ciências, Portugal
2001/10/02 - 2007/03/20 Síntese e Reactividade de 2H-Azirinas
Supervisor
 Doutoramento em Ciências, especialidade em Química (PhD)
Universidade do Minho Centro de Química, Portugal
1994/03/03 - 1997/07/18 Derivados do diaminomaleonitrilo na síntese de heterociclos
Supervisor
 Doutoramento em Ciências, especialidade em Química (PhD)
Universidade do Minho Departamento de Química, Portugal

Committee member

Activity description
Role 		Institution / Organization
2019/05/06 - 2022/05/06 Diretor Programa Doutoral em Química
Director
 Universidade do Minho Centro de Química, Portugal
2018/05/12 - 2021/05/12 Membro da Comissõa direta no triénio 2018-2021
Member
 Universidade do Minho Centro de Química, Portugal
2018/05 - 2021/05 Membro Comissão Diretiva do Mestrado em Química Medicinal
Member
 Universidade do Minho Centro de Química, Portugal
2014/01/20 - 2016/01/20 Diretor de Departamento
Director
 Universidade do Minho Departamento de Química, Portugal
2011/05/06 - 2014/05/06 Diretor do Programa Doutoral em Química no triénio 2011 2014
Director
 Universidade do Minho Departamento de Química, Portugal