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Identification

Personal identification

Full name
Maria Rita Branco Garcia

Citation names

  • Garcia, MR
  • Garcia, M.R.

Author identifiers

Ciência ID
BE19-523C-1D5B
ORCID iD
0000-0003-0914-1734

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Toxicology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Elementary (A2) Beginner (A1) Elementary (A2)
Education
Degree Classification
2023/12/13 - 2023/12/13
Concluded
 Data Analysis with R (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
2023/12/11 - 2023/12/11
Concluded
 Introduction to Data Science (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/11/07 - 2023/10/31
Attended
 PhD in Toxicology (Doutoramento)
Instituto Universitário de Ciências da Saúde, Portugal
2023/09/11 - 2023/09/22
Concluded
 Laboratory Animal Sciences (FELASA Category C) (Pós-Graduação)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Approved
2022/05/01 - 2022/07/13
Concluded
 POSTGRADUATE COURSE IN LABORATORY ANIMAL SCIENCES (CATEGORY B) - THEORETICAL (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
82/100
2018 - 2021/11/10
Concluded
 Ciências Farmacêuticas (Mestrado integrado)
Universidade do Porto Faculdade de Farmácia, Portugal
 15/20
2016 - 2018
Concluded
 Ciências Farmacêuticas (Preparatórios) (Mestrado integrado)
Universidade dos Açores - Campus de Angra do Heroísmo, Portugal
Affiliation

Others

Category
Host institution 		Employer
2022/10/01 - Current PhD student REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2022/01/25 - Current PhD student Instituto Universitário de Ciências da Saúde Unidade de Investigação em Toxicologia, Portugal
Instituto Universitário de Ciências da Saúde Unidade de Investigação em Toxicologia, Portugal
2020/01/01 - Current Master student REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2020/01/01 - Current Master student i4HB-Institute for Health and Bioeconomy, Portugal
Projects

Grant

Designation Funders
2019/09/01 - 2021/12/31 PTDC/SAU-TOX/29584/2017 NEUROSCANN
POCI-01-0145-FEDER-029584
Master student
Universidade do Porto Faculdade de Farmácia, Portugal

Other

Designation Funders
2024/03/16 - Current Desenvolvimento de uma Solução Digital Dinâmica para Capacitar a Consciência Global e a Notificação sobre Interações entre Plantas e Medicamentos
Desenvolvimento de uma Solução Digital Dinâmica para Capacitar a Consciência Global e a Notificação sobre Interações entre Plantas e Medicamentos
Other
REQUIMTE LAQV Porto, Portugal
Under evaluation
2024/03/14 - Current Perfil de segurança e potencial terapêutico da psilocibina e outros compostos de Psilocybe spp. no tratamento da depressão: Estudo pré-clínico
Perfil de segurança e potencial terapêutico da psilocibina e outros compostos de Psilocybe spp. no tratamento da depressão: Estudo pré-clínico
Other
Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Under evaluation
Outputs

Publications

Conference abstract
  1. Garcia, MR; Dutka, Mykhaylo ; Guimarães, Sofia; Andrade, Paula; Seabra, Vitor; Dias da Silva, Diana; Gomes, Nelson. "Preliminary chemical profile and in vitro pharmacological evaluation of the hallucinogenic plant Diplopterys cabrerana". Paper presented in III 1H-TOXRUN International Congress 2024, Porto, 2024.
    Published • https://doi.org/10.48797/sl.2024.221
  2. Garcia, MR; Mineiro, Tiago; Andrade, Paula; Ferreres, Federico; Gil-Izquierdo, Ángel; Seabra, Vitor; Dias da Silva, Diana; Gomes, Nelson. "Chemical characterization and in vitro studies on the impact of the 'Dream Herb' Calea zacatechichi Schltdl. upon neuronal cells". Paper presented in III 1H-TOXRUN International Congress 2024, Porto, 2024.
    Published • https://doi.org/10.48797/sl.2024.202
  3. Garcia, M.R.; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias da Silva, Diana. "Mitochondrial effects and Caspase-3 activation induced by synthetic cannabinoids in NG108-15 cells.". Paper presented in Annual Congress of APCF-TOXRUN, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.264
  4. Pereira Teixeira, Catarina; Garcia, MR; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias da Silva, Diana. "Synthetic cannabinoids affect the expression of autophagic mediators ATG5, BECLIN-1, RAB7A and LC3 in brain-derived NG108-15 cells". Paper presented in Annual Congress of APCF-TOXRUN, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.371
Conference poster
  1. Dias da Silva, Diana; Pereira Teixeira, C; Garcia, MR; Roque-Bravo, R.; Carmo, H; Carvalho, F; Silva, JP. "Crosstalk between autophagic intermediaries in the event of neurotoxic effects mediated by Synthetic Cannabinoids in NG108-15 cells". Paper presented in Lisbon Addictions, 2022.
  2. Pereira Teixeira, C; Garcia, MR; Roque Bravo, Rita; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "Synthetic cannabinoids affect expression of autophagic mediators ATG5, beclin-a, Rab7a and LC3 in NG108-15 brain-derived cells". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  3. Correia, Danilo; Cláudia Chaves; Garcia, MR. "What impact does cancer stem cell plasticity have in resistance to therapy". Paper presented in Conferences in Oncobiology 2019/20, 2019.
  4. Correia, Danilo; Ana Fernandes; Bernardo Rodrigues; Cláudia Chaves; Garcia, MR; Nayara Diniz. "Sitagliptin: a hypoglycemic used in the treatment of type 2 diabetes". Paper presented in 1ª Conferência eletrónica em Química Orgânica e Farmacêutica, 2018.
Journal article
  1. Melissa Soun-udom; Maria Rita Garcia; Andreia P. Oliveira; Paula B. Andrade; Srunya Vajrodaya; Sutsawat Duangsrisai; Nelson G.M. Gomes. "LED light treatments enhance neuroprotective properties and differentially impact phenolic compounds and triterpenoid content in Gotu Kola (Centella asiatica (L.) Urb.)". Current Plant Biology (2024): http://dx.doi.org/10.1016/j.cpb.2024.100386.
    10.1016/j.cpb.2024.100386
  2. Maria Rita Garcia; Federico Ferreres; Tiago Mineiro; Romeu A. Videira; Ángel Gil-Izquierdo; Paula B. Andrade; Vítor Seabra; Diana Dias-da-Silva; Nelson G.M. Gomes. "Mexican calea (Calea zacatechichi Schltdl.) interferes with cholinergic and dopaminergic pathways and causes neuroglial toxicity". Journal of Ethnopharmacology (2024): https://doi.org/10.1016/j.jep.2024.118915.
    10.1016/j.jep.2024.118915
  3. Maria Rita Garcia; Paula B. Andrade; Florence Lefranc; Nelson G. M. Gomes. "Marine-Derived Leads as Anticancer Candidates by Disrupting Hypoxic Signaling through Hypoxia-Inducible Factors Inhibition". Marine Drugs (2024): https://doi.org/10.3390/md22040143.
    10.3390/md22040143
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/07/04 Poster presentation: "CHEMICAL AND IN VITRO PHARMACOLOGICAL DATA TO AID A REGULATORY FRAMEWORK ON THE HALLUCINOGENIC PLANT DIPLOPTERYS CABRERANA" Encontro Ciência 2024
FCT (Porto, Portugal)
2024/05/03 "Preliminary chemical profile and in vitro pharmacological evaluation of the hallucinogenic plant Diplopterys cabrerana" III 1H-TOXRUN International Congress 2024
(Porto, Portugal)
2024/05/03 Chemical characterization and in vitro studies on the impact of the 'Dream Herb' Calea zacatechichi Schltdl. upon neuronal cells III 1H-TOXRUN International Congress 2024
1H-TOXRUN (Porto, Portugal)
2024/03/19 "Dream Herbs: Delivering data for a proper regulatory framework" Ciclo de Seminários em Farmácia
Instituto Politécnico do Porto- Escola Superior de Saúde (Porto, Portugal)
2024/02/09 Chemical profiling and in vitro pharmacological evaluation of the oneirogenic plant Calea zacatechichi Schltdl. upon neuronal cells 54th Meeting of the Portuguese Society of Pharmacology; 42nd Meeting of Clinical Pharmacology; 23rd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia (Lisbon, Portugal)
2023/11/23 Chemical characterization and in vitro studies on the impact of the oneirogenic plant Calea zacatechichi Schltdl. upon neuronal cells XVII Encontro Luso-Galego de Química
Portuguese Society of Chemistry (Porto, Portugal)
2023/07/07 Chemical characterization and in vitro studies on the impact of the oneirogenic plant Calea zacatechichi Schltdl. upon neuronal cells - Is there any need for a forensic regulatory framework? Ciência 2023 - Encontro com a Ciência e Tecnologia em Portugal
Fundação para a Ciência e a Tecnologia (Aveiro, Portugal)
2022/11/25 Crosstalk between autophagic intermediaries in the event of neurotoxic effects mediated by Synthetic Cannabinoids in NG108-15 cells Lisbon Addictions
EMCDDA (Lisbon, Portugal)
2022/05/06 Autophagic proteins ATG 5 Beclin 1 Rab 7 A and LC 3 are altered by Synthetic Cannabinoids in NG108-15 cells Scientific meetings-Young Research at University of Porto (IJUP)
University of Porto (Porto, Portugal)
2022/05/06 IN VITRO NEUROTOXICITY INDUCED BY A SET OF SYNTHETIC CANNABINOID RECEPTOR AGONISTS IN NG108-15 CELLS Scientific meetings-Young Research at University of Porto (IJUP)
University of Porto (Porto, Portugal)
2022/04/08 Synthetic cannabinoids affect expression of autophagic mediators ATG5, beclin-a Rab7a and LC3 in NG108-15 brain-derived cells 2022 Annual Congress of APCF-TOXRUN
APCF-TOXRUN (Porto, Portugal)
2022/04/08 Mitochondrial effects and caspase 3 activation induced by synthetic cannabinoids in NG108-15 cells 2022 Annual Congress of APCF-TOXRUN
APCF-TOXRUN (Porto, Portugal)
2021/10/25 NEUROTOXICITY OF A SET OF SYNTHETIC CANNABINOID RECEPTOR AGONISTS IN NG108-15 CELLS 2nd Edition of the Research Symposium of the Faculty of Pharmacy of The University of Porto (SIFFUP)
Faculty of Pharmacy of the University of Porto (Porto, Portugal)
2021/02/18 NEUROTOXICITY OF A SET OF SYNTHETIC CANNABINOID RECEPTOR AGONISTS IN NG108-15 CELLS. 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of the Toxicology
Faculty of Pharmacy of The University of Lisbon (Portugal)
2021/02/18 SYNTHETIC CANNABINOIDS INCREASE AUTOPHAGIC VACUOLES IN NG108-15 CELLS: INFLUENCE OF CB1R ACTIVATION 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of the Toxicology
Faculty of Pharmacy of The University of Lisbon (Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/02/07 - 2023/04/28 Auxiliary role (Logistics) on the Organizing Committee of the "II TOXRUN INTERNATIONAL CONGRESS 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet" (2023/04/27 - 2023/04/28)
Congress (Other)
 Instituto Universitário de Ciências da Saúde Unidade de Investigação em Toxicologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/05/27 - 2024/05/27 Conference "The Chromatography and Mass Spectrometry Techniques for the Identification of Bioactive Plant Secondary Metabolites"
Conference
 "The Chromatography and Mass Spectrometry Techniques for the Identification of Bioactive Plant Secondary Metabolites"
Universidade do Porto Faculdade de Farmácia, Portugal
2024/05/16 - 2024/05/16 Conference: "Chemical synthesis as a solution to the problem of supplying bioactive marine natural products"
Conference
 "Chemical synthesis as a solution to the problem of supplying bioactive marine natural products"
Universidade do Porto Faculdade de Farmácia, Portugal
2024/05/14 - 2024/05/14 Conference: "Drugs from the sea: an update of marine natural products in medicinal chemistry and the UDC experience"
Conference
 "Drugs from the sea: an update of marine natural products in medicinal chemistry and the UDC experience"
Universidade do Porto Faculdade de Farmácia, Portugal
2024/02/15 - 2024/02/15 Online lecture entitled “Forensic Toxicology: Overview of Psychedelics, from Prehistory to the Present”
Other
 “Forensic Toxicology: Overview of Psychedelics, from Prehistory to the Present”
Associação Portuguesa de Ciências Forenses, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
2024/02/07 - 2024/02/09 54th Meeting of the Portuguese Society of Pharmacology; 42nd Meeting of Clinical Pharmacology; 23rd Meeting of Toxicology
Meeting
 54th Meeting of the Portuguese Society of Pharmacology; 42nd Meeting of Clinical Pharmacology; 23rd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia, Portugal
2023/12/09 - 2023/12/09 Conference: "Palinologia Forense: O pólen como auxílio no Sistema de Justiça"
Conference
 Palinologia Forense: O pólen como auxílio no Sistema de Justiça
Universidade do Porto Faculdade de Farmácia, Portugal
2023/11/22 - 2023/11/24 XVII Encontro Luso-Galego de Química
Congress
 XVII Encontro Luso-Galego de Química
Sociedade Portuguesa de Química, Portugal
2023/07/05 - 2023/07/07 Ciência 2023 - Encontro com a Ciência e Tecnologia em Portugal
Conference
 Ciência 2023 - Encontro com a Ciência e Tecnologia em Portugal
Fundação para a Ciência e a Tecnologia, Portugal
2023/04/27 - 2023/04/28 II TOXRUN INTERNATIONAL CONGRESS 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet
Congress
 II TOXRUN INTERNATIONAL CONGRESS 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet"
Instituto Universitário de Ciências da Saúde Unidade de Investigação em Toxicologia, Portugal
2023/04/04 - 2023/04/04 Conference: "The Richness of the Medicinal Plants of Turkey"
Conference
 The Richness of the Medicinal Plants of Turkey
Universidade do Porto Faculdade de Farmácia, Portugal
2020/02/16 - 2020/02/18 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of the Toxicology
Conference
 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of the Toxicology
Sociedade Portuguesa de Farmacologia, Portugal
2019/12/03 - 2019/12/03 Conferences in Oncobiology 2019/2020
Conference
 Conferences in Oncobiology 2019/2020
Universidade do Porto Faculdade de Farmácia, Portugal
2018/11/30 - 2018/11/30 Conferência Eletrónica em Química Orgânica e Farmacêutica
Conference
 1ª Conferência eletrónica em Química Orgânica e Farmacêutica
Universidade do Porto Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/07/04 Inhibition of cytochrome P450 isoenzymes by classic hallucinogens
(Thesis) Main arguer
 Steven Van Droogenbroeck (Other)
Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal

Mentoring / Tutoring

Topic Student name
2024/02/01 - Current "Delivering chemical and pharmacological data for an appropriate regulatory framework on psychoactive plants" Sofia Guimarães
2024/01/01 - Current "Chemical characterization of the Ayahuasca ingredient Chaliponga (Diplopterys cabrerana) and impact upon neurological events" Mykhaylo Dutka