Alexandre Augusto da Silva Figueiredo e Raposo (C113-64CC-5065)

Curriculum Vitae

Alexandre Augusto da Silva Figueiredo e Raposo

Alexandre Augusto da Silva Figueiredo e Raposo. Completed the Licenciatura in Engenharia Física Tecnológica in 1999 by Universidade de Lisboa Instituto Superior Técnico and Doctor of Philosophy in Biology in 2009/02/21 by University of Cambridge. Is Auxiliary Researcher in Instituto de Medicina Molecular. Published 11 articles in journals. Participated in 8 event(s). Supervised 1 MSc dissertation(s) e co-supervised 1. Has received 5 awards and/or honors. Participates and/or participated as Pos-doctoral Fellow in 2 project(s) and Researcher in 2 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Immunology, Natural sciences with emphasis on Biological Sciences with emphasis on Cell Biology, Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics and Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Gene-based Diagnostics and Therapeutic Interventions. In their professional activities interacted with 58 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Data analysis; Precision Medicine; Health technologies; Oncology; Immunology; mRNA localization; RNA biology; regulation of gene expression; neurogenesis; proneural factor; ChIP-on-chip/ChIP-seq; transcription; Neurogenesis; Mash1/Ascl1; Notch; ChIP-seq; Drosophila; nuclear migration; cytoskeleton; cell polarity; Gene Expression; Epigenetics; Reprogramming; Transcription Regulation; Stem Cells; RNAi; Microscopy; Cell culture; DNA Transfection; Immunostaining; Live Imaging; Hippocampal Neurons; Computational Biology; Genomics; Cell Biology; Neural Stem Cells; Chromatin; Functional Genomics; Gene Regulatory Networks; Data mining; Knowledege Discovery; Drug discovery; Complex Disease; Transcriptomics; Bioinformatics; NGS; Human Genomics; Multifactorial Disorders; Machine Learning; T cells; Common Variable Immunodeficiency; Optical Networks; SDH; Systems Engineering; Telecom; Autoimmunity; Inborn Errors of Immunity; Immune Complex Disorders; .

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Identification

Personal identification

Full name: Alexandre Augusto da Silva Figueiredo e Raposo

Citation names

Raposo, AASF

Author identifiers

Ciência ID: C113-64CC-5065
ORCID iD: 0000-0002-2794-0508

Email addresses

alexandre.raposo@medicina.ulisboa.pt (Professional)

Addresses

Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa. Avenida Professor Egas Moniz, 1649-028 L, Lisboa, Lisboa, Portugal (Professional)

Websites

https://imm.medicina.ulisboa.pt/en/ (Professional)

Knowledge fields

Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
Medical and Health Sciences - Basic Medicine - Immunology
Exact Sciences - Computer and Information Sciences - Bioinformatics
Natural sciences - Biological Sciences - Cell Biology

Languages

Language	Speaking	Reading	Writing	Listening
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
German	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)
Spanish; Castilian	Intermediate (B1)	Intermediate (B1)	Beginner (A1)	Intermediate (B1)
Portuguese (Mother tongue)

Education

	Degree	Classification
2009/02/21 Concluded	Biology (Doctor of Philosophy) University of Cambridge, United Kingdom "Nuclear migration and the regulation of microtubules in the Drosophila oocyte" (THESIS/DISSERTATION)	n/a
1999 Concluded	Engenharia Física Tecnológica (Licenciatura) Universidade de Lisboa Instituto Superior Técnico, Portugal "Diagnósticos ópticos em plasmas de fusão termonuclear" (THESIS/DISSERTATION)	14

Affiliation

Science

	Category Host institution	Employer
2019/03/01 - Current	Auxiliary Researcher (Research)	Instituto de Medicina Molecular, Portugal

2017/03/27 - 2019/03/01	Contracted Researcher (Research)	Instituto de Medicina Molecular, Portugal

2010/07/12 - 2017/03/27	Postdoc (Research)	Instituto Gulbenkian de Ciência, Portugal
	Instituto Gulbenkian de Ciência, Portugal
2008/04/12 - 2010/07/31	Postdoc (Research)	Medical University of Vienna Center for Brain Research, Austria

Others

	Category Host institution	Employer
2002/09/01 - 2003/07/31	Post-graduate student 3rd Gulbenkian PhD Programme in Biomedicine	Instituto Gulbenkian de Ciência, Portugal

2001/01/01 - 2002/07/31	Systems and Telecom engineer Research/Engineering/Teaching	Siemens SA, Spain

2000/09/01 - 2000/12/31	Systems Analyst for web and databases	BPI, Portugal

Projects

Grant

	Designation	Funders
2013/01 - 2015/01	Transcriptional Integration of Notch and Proneural pathways in vertebrate neurgenesis PTDC/NEU-NMC/0315/2012 Researcher Instituto Gulbenkian de Ciência, Portugal National Institute for Medical Research, United Kingdom	Foundation for Science and Tecnology Concluded
2010/04 - 2013/06	Characterization of a neurogenic program activated by the proneural factor Mash1 100208 Post-doc Fellow Instituto Gulbenkian de Ciência, Portugal National Institute for Medical Research, United Kingdom	Fundação para a Ciência e a Tecnologia, I.P. Concluded

Contract

	Designation	Funders
2024/09/10 - Current	GLIM-BioData – Gateway for Living Data Management RE-C05-i08 RI/00138/2024 BioData.pt, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	Institute of Molecular Medicine João Lobo Antunes LA/P/0082/2020 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/03/29 - 2024/09/28	Targeting naïve CD4 T cells to avoid human immunodeficiency PTDC/MED-IMU/0938/2020 10.54499/PTDC/MED-IMU/0938/2020 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/06/01 - 2021/05/31	Células T foliculares no cerne da infecção HIV PTDC/MED-IMU/30474/2017 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2019/01/01 - 2019/12/31	Instituto de Medicina Molecular UID/BIM/50005/2019 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017/04/12 - 2019/09/30	PRECISE-Accelerating progress toward the new era of precision medicine SAICTPAC/0021/2015 Researcher Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04/04 - 2013/06/30	Caracterização de um programa de neurogénese activado pelo factor proneural Mash1 PTDC/SAU-NEU/100208/2008 National Institute for Medical Research, United Kingdom Fundação Calouste Gulbenkian, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2008/04/12 - 2010/08/01	A link between RNA localization, mRNA degradation and miRNA-mediated translational silencing API00127FW Post-doc Fellow Medical University of Vienna Center for Brain Research, Austria	European Science Foundation Concluded

Outputs

Publications

Conference poster	Conti, Eller; Rosmaninho, Pedro; Moleirinho, Beatriz; Marques, Madalena; Afonso RM Almeida; Ana Espada de Sousa; Raposo, AASF. "Chromatin Landscapes Controlling CD8 Regulatory T Cells in The Human Thymus". Paper presented in ThymE 24: T Cell & Thymus Biology, 2024. Conti, Eller; Rosmaninho, Pedro; Moleirinho, Beatriz; Marques, Madalena; Afonso RM Almeida; Ana Espada de Sousa; Raposo, AASF. "Defining a CD8 Regulatory T Cell Lineage in The Human Thymus". Paper presented in 17th ENII EFIS EJI Summer School on Advanced Immunology, 2024. Paulo-Pedro, Margarida; Moleirinho, Beatriz; Diana F Santos; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Raposo, AASF; Afonso RM Almeida; Ana Espada de Sousa. "The T-cell compartment at a single-cell level 17 years post thymus transplantation in a patient with FOXN1 mutation". Paper presented in SPI’49 XLIX Annual Meeting Portuguese Society for Immunology, 2024. Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; PAÇO, SUSANA; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". Paper presented in 12th ESLHO Symposium on New developments in flow cytometry, immunogenetics and MRD assessment, 2023. Raposo, AASF; Rosmaninho, Pedro; PAÇO, SUSANA; Ângelo-Dias, M; Godinho-Santos, Ana; Nunes-Cabaço, Helena; Tokunaga-Mizoro, Yumie; et al. "Differential Binding in human thymic regulatory T cells refine whole-genome analyses of complex immune diseases". Paper presented in XLVIII Annual Meeting of the Portuguese Society for Immunology, 2023.
Journal article	Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; PAÇO, SUSANA; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". Genome Research (2024): Open access • Submitted Marta F Fidalgo; Catarina G Fonseca; Paulo Caldas; Alexandre ASF Raposo; Tania Balboni; Lenka Henao-Mišíková; Ana R Grosso; Francisca F Vasconcelos; Cláudio A Franco. "Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes". Life Science Alliance (2022): https://doi.org/10.26508/lsa.202201554. 10.26508/lsa.202201554 Monteiro FA; Miranda RM; Samina MC; Dias AF; Raposo AASF; Oliveira P; Reguenga C; Castro DS; Lima D. "Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory Neurons in the Dorsal Spinal Cord.". Frontiers in cell and developmental biology (2021): http://europepmc.org/abstract/med/33996801. 10.3389/fcell.2021.642697 Silva, Susana L.; Fonseca, Mariana; Pereira, Marcelo L. M.; Silva, Sara P.; Barbosa, Rita R.; Serra-Caetano, Ana; Blanco, Elena; et al. "Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden". Frontiers in Immunology 10 (2019): http://dx.doi.org/10.3389/fimmu.2019.02503. 10.3389/fimmu.2019.02503 Raposo, AASF. "PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination.". Cell reports (2019): http://europepmc.org/articles/PMC6486480. 10.1016/j.celrep.2019.03.108 Pedro Rosmaninho; Susanne Mükusch; Valerio Piscopo; Vera Teixeira; Alexandre ASF Raposo; Rolf Warta; Romina Bennewitz; et al. "Zeb1 potentiates genome-wide gene transcription with Lef1 to promote glioblastoma cell invasion". The EMBO Journal (2018): e97115-e97115. https://doi.org/10.15252/embj.201797115. 10.15252/embj.201797115 Vasconcelos FF; Sessa A; Laranjeira C; Raposo AA; Teixeira V; Hagey DW; Tomaz DM; et al. "MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis.". (2016): http://europepmc.org/abstract/med/27705795. 10.1016/j.celrep.2016.09.024 Shalini Singh; Danielle Howell; Niraj Trivedi; Ketty Kessler; Taren Ong; Pedro Rosmaninho; Alexandre ASF Raposo; et al. "Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition". eLife 5 (2016): https://doi.org/10.7554/eLife.12717. 10.7554/eLife.12717 Raposo, Alexandre; Raposo, A.A.S.F.; Vasconcelos, F.F.; Drechsel, D.; Marie, C.; Johnston, C.; Dolle, D.; et al. "Ascl1 coordinately regulates gene expression and the chromatin landscape during neurogenesis". Cell Reports 10 9 (2015): 1544-1556. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931281902&partnerID=MN8TOARS. http://dx.doi.org/10.1016/j.celrep.2015.02.025 Raposo, Alexandre. "A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development". Frontiers in Neuroscience (2014): 10.3389/fnins.2014.00257 Zhao T; Graham OS; Raposo A; St Johnston D. "Growing microtubules push the oocyte nucleus to polarize the Drosophila dorsal-ventral axis.". (2012): http://europepmc.org/abstract/med/22499806. 10.1126/science.1219147 Konecna A; Heraud JE; Schoderboeck L; Raposo AA; Kiebler MA. "What are the roles of microRNAs at the mammalian synapse?". (2009): http://europepmc.org/abstract/med/19545603. 10.1016/j.neulet.2009.06.050 Dahlgaard K; Raposo AA; Niccoli T; St Johnston D. "Capu and Spire assemble a cytoplasmic actin mesh that maintains microtubule organization in the Drosophila oocyte.". (2007): http://europepmc.org/abstract/med/17925229. 10.1016/j.devcel.2007.09.003 Stevens NR; Raposo AA; Basto R; St Johnston D; Raff JW. "From stem cell to embryo without centrioles.". (2007): http://europepmc.org/abstract/med/17716897. 10.1016/j.cub.2007.07.060
Preprint	Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; Paço, Susana; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. Corresponding author: Raposo, AASF. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". 2023. http://dx.doi.org/10.1101/2023.12.27.573411. 10.1101/2023.12.27.573411 Marta F. Fidalgo; Catarina G. Fonseca; Paulo Caldas; Alexandre A. S. F. Raposo; Tania Balboni; Ana R. Grosso; Francisca F. Vasconcelos; Cláudio A. Franco. "Alternative splicing changes are associated with pre-birth adaptation during lung development". 2022. https://doi.org/10.1101/2022.01.19.476886. 10.1101/2022.01.19.476886 Falcão, Ana Mendanha; Meijer, Mandy; Scaglione, Antonella; Rinwa, Puneet; Agirre, Eneritz; Liang, Jialiang; Larsen, Sara C.; et al. "PADI2-mediated citrullination is required for efficient oligodendrocyte differentiation and myelination". 2018. http://dx.doi.org/10.1101/425348. 10.1101/425348

Intellectual property

Provisional application for patent

2023. "Genomic Mutations".
Protected • 10.5281/zenodo.10684403.

Other

Software

Raposo, AASF; Tiago João Carrilho Lima do Val. "ASAP - ATAC-Seq Automated Pipeline". Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes. This version was developed for iMM-LOBO HPC, with Slurm/Shifter.. 2023.
https://zenodo.org/doi/10.5281/zenodo.10683658

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/05/24	Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells	15TH INTERNATIONAL SYMPOSIUM ON VARIANTS IN THE GENOME HUGO - Human Genome Organisation (Póvoa de Varzim, Porto, Portugal)
2023/11/17	Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells	3rd Symposium of the National Research Infrastructure for Genome Sequencing and Analyisis (“GenomePT Symposium”) National Institute of Health Doutor Ricardo Jorge (INSA) (Lisbon, Portugal)
2021/05/20	The signature of human regulatory CD4 thymocytes and its modulation by the chromatin landscape	XLVI Annual Meeting of the Portuguese Society for Immunology Portuguese Society for Immunology (online) (Portugal)
2020/10/14	The signature of human CD4 regulatory thymocytes and its modulation by the chromatin landscape	19th Biennial Meeting of the European Society for Immunodeficiencies European Society for Immunodeficiencies (Birmingham, United Kingdom)
2019/09/20	Homeostasis of Human NaÏve CD4 T Cells: Changes in Transcriptomes of Regulatory or Conventional Cells Reveal Distinct Mechanisms of Maintenance Independent of Thymic Output	2019 Focused Meeting of the European Society for Immunodeficiencies - Malignancy and PID European Society for Immunodeficiencies (Brussels, Belgium)
2018/10/25	Transcriptional Signature of Thymic-committed Human Regulatory T Cells	18th Biennial Meeting of the European Society for Immunodeficiencies European Society for Immunodeficiencies (Lisbon, Portugal)
2015/10/10	selected abstract: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis"	3rd Joint Meeting of the Societies for Developmental Biology SPBD (PT), SEBD (ES), and BSDB (UK) Sociedade de Biologia do Desenvolvimento (Albufeira, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2019/09/01 - 2021/11/30	Data Science Methods Applied to the Study of The Signature of Regulatory CD4 T Cells in the Human Thymus and its modulation by the Chromatin Landscape Co-supervisor of Susana Maria Santos do Paço	Mestrado em Métodos Analíticos Avançados (Master) Instituto de Medicina Molecular, Portugal Universidade Nova de Lisboa Instituto Superior de Estatística e Gestão de Informação, Portugal
2018 - 2019	Identification of novel potential therapeutic targets for T-cell Acute Lymphoblastic Leukemia Co-supervisor	Mestrado Integrado em Medicina (Master) Universidade de Lisboa Faculdade de Medicina, Portugal
2017 - 2018	Uncovering the regulatory T cell transcriptional signature in the human thymus Supervisor of Miguel Ângelo Simão Dias	Mestrado de Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2024/11/19 - 2024/11/19	Meeting of members of the Federated Human Data Community of the ELIXIR consortium Meeting	Elixir Federated Human Data Community F2F/hybrid meeting ELIXIR Europe, United Kingdom BioData.pt, Portugal
2024/11/07 - 2024/11/07	Symposium of the European Scientific Foundation for Laboratory Hemato-oncology (ESLHO) Symposium	13th ESLHO Symposium on Multi-omics approaches for diagnosis and monitoring of hematological malignancies. European Scientific Foundation for Laboratory Hemato-oncology (ESLHO), Netherlands
2024/05/12 - 2024/05/12	Workshop preceding conference on the ACMG-AMP classification system, the UCSC recommended track set, HGVS Nomenclature and gene variant databases. Workshop	15th International Symposium on Variants in the Genome: Optional Workshop Day Sociedade Portuguesa de Genética Humana, Portugal Human Genome Organization (HUGO), United States
2016/10 - 2016/10	Poster presentation: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" Raposo AASF*, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DL, Ettwiller L, Flicek P, Crawford GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS Conference	Big Data in Biology and Health EMBL Heidelberg Genome Biology, Germany
2016/09/01 - 2016/09/02	Poster presentation: "Functional Genomics of Neurogenesis: A crosstalk between Notch/RBPJ and Ascl1 Transcriptional pathways" Raposo AASF, Vasconcelos FF, Laranjeira C, Castro DS, EMBO Young Scientists' Forum 2016, 1-2 September 2016, Lisbon, Portugal Meeting	EMBO Young Scientists' Forum 2016 European Molecular Biology Organisation , Germany
2015/11/30 - 2015/12/03	Hands-on workshop on Translational Bioinformatics in Heath and Disease, from data mining of human genomic databases to drug discovery Workshop	TBHD15 Translational Bioinformatics in Heath and Disease Instituto Gulbenkian de Ciência, Portugal
2015/09/28 - 2015/10/01	Hands-on workshop on Genomic Architecture of Complex Traits Workshop	GACT15 Genomic Architecture of Complex Traits Instituto Gulbenkian de Ciência, Portugal
2015/06/04 - 2015/06/05	Poster presentation: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" Raposo AASF*, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DL, Ettwiller L, Flicek P, Crawford GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS, Conference	XIV Meeting of Portuguese Society for Neuroscience Sociedade Portuguesa de Neurociências, Portugal
2013/09/14 - 2013/09/21	Workshop: tools/public data resources in neurogenomics and brain diseases. Mornings/evenings with lectures on areas in which large datasets are available, such as the synaptic complex, synaptic plasticity, mRNAs, neuro-ontology, neurogenomics, and neurogenesis. In the afternoons, students and lecturers worked to apply the new tools and datasets to answer specific research questions. By the end of the course we had six jointly written draft papers for each of the questions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341549 Workshop	INCF short course on neuroinformatics, neurogenomics, and brain disease International Neuroinformatics Coordinating Facility, Sweden
2012/10 - 2012/10	Poster presentation: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" Raposo AASF*, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DL, Ettwiller L, Flicek P, Crawford GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS Conference	From Functional Genomics to Systems Biology EMBL Heidelberg Genome Biology, Germany
2011/09/05 - 2011/09/09	Hands-on workshop on Microarray Data Analysis using R and Bioconductor Workshop	MDARB11 Microarray Data Analysis using R and Bioconductor Instituto Gulbenkian de Ciência, Portugal
2011 - 2011	EMBL-European Bioinformatics Institute Workshop: Advanced Next-Generation Sequencing ChIP-seq Data analysis and European Nucleotide Archive database course. Workshop	Advanced Next-Generation Sequencing Bioinformatics European Bioinformatics Institute, United Kingdom

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2024/10/22	Deciphering FOXO1-Mediated Gene Regulation Through Multi-Omics Integration http://hdl.handle.net/10362/174682 (Thesis) Main arguer	FREDERICO DIAS ÁGUA (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/12/12	Computational Analysis of FoxO1-mediated transcriptome alterations in Endothelial cells (Thesis) Main arguer	Paulo Ricardo Viana Mendonça (Master) Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/11/07	Single-cell transcriptional landscape of circulating Tfh nd Treg cells in COVID-19 patients (Thesis) Main arguer	Diogo Martins Fonseca (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2024/10/20 - 2024/11/21	Molecular Biology Reports (0301-4851)	Springer Science+Business Media

Association member

	Society Organization name	Role
2023/10/10 - Current	Sociedade Portuguesa de Genética Humana	Member
2022/01/01 - Current	ERN RITA – European Reference Network for Immunodeficiency, autoinflammatory and autoimmune diseases	Participant
2022/01/01 - Current	Co-Lab AccelBio https://accelbio.pt/	Participant
2020/01/01 - Current	Estratégia Nacional para a Medicina Genómica - PT_MedGen	iMM node representative
2018 - Current	Sociedade Portuguesa de Imunologia	member
2018 - Current	European Society of Immunodeficiency	member
2017/05/01 - Current	Beyond One Million Genomes. A distributed genome sequencing and analysis infrastructure integrated in the Portuguese Roadmap of Research Infrastructures. It congregates over 50 researchers and technical personnel and amasses important bioinformatics expertise into a single genomics consortium.	Participant in workgroup 6, "Health economics and outcome research"
2017/04/30 - Current	GenomePT	iMM node member
2021/10/06 - 2025/10/05	Mye-INFOBANK COST Action (European cooperation in Science and Technology) Converting molecular profiles of myeloid cells into biomarkers for inflammation and cancer	Participant in Workgroup Mye-Matrix (Omics, data, computational biology)

Conference scientific committee

	Conference name	Conference host
2024/04/16 - 2024/04/19	Annual International (Bio)Medical Students Meeting - AIMS Meeting 2024	Medical School of the University of Lisbon
2023/11 - 2023/11	3rd Symposium of the National Research Infrastructure for Genome Sequencing and Analysis	National Institute of Health Doutor Ricardo Jorge
2022/03/10 - 2022/03/13	AIMS Meeting 2022	Medical School of the University of Lisbon
2012/10/03 - 2012/10/05	HCist'2012 - International Conference on Health and Social Care Information Systems and Technology

Consulting

	Activity description	Institution / Organization
2010 - 2010	GoBusiness/FCT-UNL, "A stock market crash alarm system based on a Hurst Index Neural Network", 2010	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2001 - 2001	Training of Siemens SA clients in Management, Operation and Maintenance of Optical Networks and their equipment. Engineer level, to Vodafone and Portugal Telecom in Portugal; Airtel and Telefónica in Spain.	Siemens SA, Portugal, Portugal

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2023/11/13 - 2023/12/20	"Modelling multiomics data for Precision Medicine"	Data Science and Engineering (Mestrado)	Universidade de Lisboa Instituto Superior Técnico, Portugal
2009/11/23 - 2009/11/25	Basics of Neuroscience – first course 4.11. 2009 to 4.12.2009 Lectures and laboratorial work. Lecturers: Prof. Dr. Michael Kiebler, Dr. Georgia Vendra, Dr. Alexandre Raposo	Neuronal Cell Biology (Magister)	Medical University of Vienna Center for Brain Research, Austria
2009 - 2009	Advanced Neuronal Cell Biology	Advanced Neuronal Cell Biology (Doktor (PhD))	Medical University of Vienna Center for Brain Research, Austria

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2012/05	Interview upon publication "Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila D-V Axis", Science, 2012: «Alexandre Raposo contribui para nova visão sobre o desenvolvimento da Drosophila»	"CienciaHoje", a digital news outlet for science. Original URL broken.

Interview (tv / radio show)

	Program	Topic
2021/05/29 - Current	Weekly show "Os Dias do Futuro", Antena 1 national radio (RTP), focused on science, researchers, and innovation. https://www.rtp.pt/play/p383/e548566/os-dias-do-futuro https://www.rtp.pt/programa/radio/p3000	My professional trajectory and research. Here I had the opportunity to describe my work on Precision Medicine at the IMM.
2012/10/15 - 2012/10/15	Antena 2 Ciência, interview to comment on Nobel Prize Physiology or Medicine 2012, given to Sir John Gurdon and S. Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"	O nobéis de medicina, física e química - o que pode mudar nas nossas vidas por causa do trabalho dos cientistas, agora galardoados.
2012/05/07 - 2012/05/07	Antena 2 Ciência: Os trabalhos e os dias dos cientistas e o que muda nas nossas vidas "Núcleo da Célula" (in PT). I was interviewed about my publication of "Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila D-V Axis" in Science, 2012	Nuclear migration and cell polarity

Journal scientific committee

	Journal title (ISSN)	Publisher
2022/10/10 - 2022/10/24	Immunology Letters (0165-2478)	Elsevier

Mentoring / Tutoring

	Topic	Student name
2022/12/05 - 2023/12/15	Variant calling of Human Genomes in a High-Performance Computer cluster environment	Maria Escórcio Brazão
2019/09/01 - 2020/09/01	Benchmarking of clustering algorithms for analysis of human CD4 T cell transcriptomes	Susana Maria Santos do Paço
2017 - 2018	RNA-seq Data Analysis	Francisca Ferreira Vasconcelos
2017 - 2017	Next Generation Sequencing Data Analysis	Marta Ferreira
2017 - 2017	High-Performance Computer Cluster with SLURM/Docker	Several users of the HPC cluster LOBO

Distinctions

Other distinction

2018	CEEC Assistant Researcher contract Fundação para a Ciência e a Tecnologia, Portugal
2012	Fee waiver European Molecular Biology Laboratory, Germany
2003	PhD Studentship Fundação para a Ciência e a Tecnologia, Portugal
2002	PhD Biomedicine Programme studentship Fundação Calouste Gulbenkian, Portugal
1996	Studentship EU Framework Programme for Research and Innovation Euratom, Belgium