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Alexandre Augusto da Silva Figueiredo e Raposo. Completed the Licenciatura in Engenharia Física Tecnológica in 1999 by Universidade de Lisboa Instituto Superior Técnico and Doctor of Philosophy in Biology in 2009/02/21 by University of Cambridge. Is Auxiliary Researcher in Instituto de Medicina Molecular. Published 11 articles in journals. Participated in 8 event(s). Supervised 1 MSc dissertation(s) e co-supervised 1. Has received 5 awards and/or honors. Participates and/or participated as Pos-doctoral Fellow in 2 project(s) and Researcher in 2 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Immunology, Natural sciences with emphasis on Biological Sciences with emphasis on Cell Biology, Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics and Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Gene-based Diagnostics and Therapeutic Interventions. In their professional activities interacted with 58 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Data analysis; Precision Medicine; Health technologies; Oncology; Immunology; mRNA localization; RNA biology; regulation of gene expression; neurogenesis; proneural factor; ChIP-on-chip/ChIP-seq; transcription; Neurogenesis; Mash1/Ascl1; Notch; ChIP-seq; Drosophila; nuclear migration; cytoskeleton; cell polarity; Gene Expression; Epigenetics; Reprogramming; Transcription Regulation; Stem Cells; RNAi; Microscopy; Cell culture; DNA Transfection; Immunostaining; Live Imaging; Hippocampal Neurons; Computational Biology; Genomics; Cell Biology; Neural Stem Cells; Chromatin; Functional Genomics; Gene Regulatory Networks; Data mining; Knowledege Discovery; Drug discovery; Complex Disease; Transcriptomics; Bioinformatics; NGS; Human Genomics; Multifactorial Disorders; Machine Learning; T cells; Common Variable Immunodeficiency; Optical Networks; SDH; Systems Engineering; Telecom; Autoimmunity; Inborn Errors of Immunity; Immune Complex Disorders; .
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Identification

Personal identification

Full name
Alexandre Augusto da Silva Figueiredo e Raposo

Citation names

  • Raposo, AASF

Author identifiers

Ciência ID
C113-64CC-5065
ORCID iD
0000-0002-2794-0508

Email addresses

  • alexandre.raposo@cantab.net (Professional)

Addresses

  • Gulbenkian Institute for Molecular Medicine, Avenida Professor Egas Moniz, 1649-028, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Natural sciences - Biological Sciences - Cell Biology
  • Exact Sciences - Computer and Information Sciences - Bioinformatics

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Portuguese (Mother tongue)
Education
Degree Classification
2009/02/21
Concluded
 Biology (Doctor of Philosophy)
University of Cambridge, United Kingdom
"Nuclear migration and the regulation of microtubules in the Drosophila oocyte" (THESIS/DISSERTATION)
 n/a
1999/09
Concluded
 Engenharia Física Tecnológica (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Diagnósticos ópticos em plasmas de fusão termonuclear" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2019/03/01 - Current Auxiliary Researcher (Research) Instituto de Medicina Molecular, Portugal
2017/03/27 - 2019/03/01 Contracted Researcher (Research) Instituto de Medicina Molecular, Portugal
2010/07/12 - 2017/03/27 Postdoc (Research) Instituto Gulbenkian de Ciência, Portugal
Instituto Gulbenkian de Ciência, Portugal
2008/04/12 - 2010/07/31 Postdoc (Research) Medical University of Vienna Center for Brain Research, Austria

Others

Category
Host institution 		Employer
2002/09/01 - 2003/07/31 Post-graduate student 3rd Gulbenkian PhD Programme in Biomedicine Instituto Gulbenkian de Ciência, Portugal
2001/01/01 - 2002/07/31 Systems and Telecom engineer Research/Engineering/Teaching Siemens SA, Spain
2000/09/01 - 2000/12/31 Systems Analyst for web and databases BPI, Portugal
Projects

Grant

Designation Funders
2013/01 - 2015/01 Transcriptional Integration of Notch and Proneural pathways in vertebrate neurgenesis
PTDC/NEU-NMC/0315/2012
Researcher
Instituto Gulbenkian de Ciência, Portugal

National Institute for Medical Research, United Kingdom
Foundation for Science and Tecnology
Concluded
2010/04 - 2013/06 Characterization of a neurogenic program activated by the proneural factor Mash1
100208
Post-doc Fellow
Instituto Gulbenkian de Ciência, Portugal

National Institute for Medical Research, United Kingdom
Fundação para a Ciência e a Tecnologia, I.P.
Concluded

Contract

Designation Funders
2024/09/10 - Current GLIM-BioData – Gateway for Living Data Management
RE-C05-i08
RI/00138/2024
BioData.pt, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Institute of Molecular Medicine João Lobo Antunes
LA/P/0082/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/03/29 - 2024/09/28 Targeting naïve CD4 T cells to avoid human immunodeficiency
PTDC/MED-IMU/0938/2020
10.54499/PTDC/MED-IMU/0938/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/01 - 2021/05/31 Células T foliculares no cerne da infecção HIV
PTDC/MED-IMU/30474/2017
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2017/04/12 - 2019/09/30 PRECISE-Accelerating progress toward the new era of precision medicine
SAICTPAC/0021/2015
Researcher
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/04/04 - 2013/06/30 Caracterização de um programa de neurogénese activado pelo factor proneural Mash1
PTDC/SAU-NEU/100208/2008
National Institute for Medical Research, United Kingdom

Fundação Calouste Gulbenkian, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/04/12 - 2010/08/01 A link between RNA localization, mRNA degradation and miRNA-mediated translational silencing
API00127FW
Post-doc Fellow
Medical University of Vienna Center for Brain Research, Austria
 European Science Foundation
Concluded
Outputs

Publications

Conference poster
  1. Conti, Eller; Rosmaninho, Pedro; Moleirinho, Beatriz; Marques, Madalena; Afonso RM Almeida; Ana Espada de Sousa; Raposo, AASF. "Chromatin Landscapes Controlling CD8 Regulatory T Cells in The Human Thymus". Paper presented in ThymE 24: T Cell & Thymus Biology, 2024.
  2. Conti, Eller; Rosmaninho, Pedro; Moleirinho, Beatriz; Marques, Madalena; Afonso RM Almeida; Ana Espada de Sousa; Raposo, AASF. "Defining a CD8 Regulatory T Cell Lineage in The Human Thymus". Paper presented in 17th ENII EFIS EJI Summer School on Advanced Immunology, 2024.
  3. Paulo-Pedro, Margarida; Moleirinho, Beatriz; Diana F Santos; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Raposo, AASF; Afonso RM Almeida; Ana Espada de Sousa. "The T-cell compartment at a single-cell level 17 years post thymus transplantation in a patient with FOXN1 mutation". Paper presented in SPI’49 XLIX Annual Meeting Portuguese Society for Immunology, 2024.
  4. Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; PAÇO, SUSANA; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". Paper presented in 12th ESLHO Symposium on New developments in flow cytometry, immunogenetics and MRD assessment, 2023.
  5. Raposo, AASF; Rosmaninho, Pedro; PAÇO, SUSANA; Ângelo-Dias, M; Godinho-Santos, Ana; Nunes-Cabaço, Helena; Tokunaga-Mizoro, Yumie; et al. "Differential Binding in human thymic regulatory T cells refine whole-genome analyses of complex immune diseases". Paper presented in XLVIII Annual Meeting of the Portuguese Society for Immunology, 2023.
Journal article
  1. Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; PAÇO, SUSANA; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". Genome Research (2024):
    Open access • Submitted
  2. Marta F Fidalgo; Catarina G Fonseca; Paulo Caldas; Alexandre ASF Raposo; Tania Balboni; Lenka Henao-Mišíková; Ana R Grosso; Francisca F Vasconcelos; Cláudio A Franco. "Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes". Life Science Alliance (2022): https://doi.org/10.26508/lsa.202201554.
    10.26508/lsa.202201554
  3. Monteiro FA; Miranda RM; Samina MC; Dias AF; Raposo AASF; Oliveira P; Reguenga C; Castro DS; Lima D. "Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory Neurons in the Dorsal Spinal Cord.". Frontiers in cell and developmental biology (2021): http://europepmc.org/abstract/med/33996801.
    10.3389/fcell.2021.642697
  4. Silva, Susana L.; Fonseca, Mariana; Pereira, Marcelo L. M.; Silva, Sara P.; Barbosa, Rita R.; Serra-Caetano, Ana; Blanco, Elena; et al. "Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden". Frontiers in Immunology 10 (2019): http://dx.doi.org/10.3389/fimmu.2019.02503.
    10.3389/fimmu.2019.02503
  5. Raposo, AASF. "PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination.". Cell reports (2019): http://europepmc.org/articles/PMC6486480.
    10.1016/j.celrep.2019.03.108
  6. Pedro Rosmaninho; Susanne Mükusch; Valerio Piscopo; Vera Teixeira; Alexandre ASF Raposo; Rolf Warta; Romina Bennewitz; et al. "Zeb1 potentiates genome-wide gene transcription with Lef1 to promote glioblastoma cell invasion". The EMBO Journal (2018): e97115-e97115. https://doi.org/10.15252/embj.201797115.
    10.15252/embj.201797115
  7. Vasconcelos FF; Sessa A; Laranjeira C; Raposo AA; Teixeira V; Hagey DW; Tomaz DM; et al. "MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis.". (2016): http://europepmc.org/abstract/med/27705795.
    10.1016/j.celrep.2016.09.024
  8. Shalini Singh; Danielle Howell; Niraj Trivedi; Ketty Kessler; Taren Ong; Pedro Rosmaninho; Alexandre ASF Raposo; et al. "Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition". eLife 5 (2016): https://doi.org/10.7554/eLife.12717.
    10.7554/eLife.12717
  9. Raposo, Alexandre; Raposo, A.A.S.F.; Vasconcelos, F.F.; Drechsel, D.; Marie, C.; Johnston, C.; Dolle, D.; et al. "Ascl1 coordinately regulates gene expression and the chromatin landscape during neurogenesis". Cell Reports 10 9 (2015): 1544-1556. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931281902&partnerID=MN8TOARS.
    http://dx.doi.org/10.1016/j.celrep.2015.02.025
  10. Raposo, Alexandre. "A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development". Frontiers in Neuroscience (2014):
    10.3389/fnins.2014.00257
  11. Zhao T; Graham OS; Raposo A; St Johnston D. "Growing microtubules push the oocyte nucleus to polarize the Drosophila dorsal-ventral axis.". (2012): http://europepmc.org/abstract/med/22499806.
    10.1126/science.1219147
  12. Konecna A; Heraud JE; Schoderboeck L; Raposo AA; Kiebler MA. "What are the roles of microRNAs at the mammalian synapse?". (2009): http://europepmc.org/abstract/med/19545603.
    10.1016/j.neulet.2009.06.050
  13. Dahlgaard K; Raposo AA; Niccoli T; St Johnston D. "Capu and Spire assemble a cytoplasmic actin mesh that maintains microtubule organization in the Drosophila oocyte.". (2007): http://europepmc.org/abstract/med/17925229.
    10.1016/j.devcel.2007.09.003
  14. Stevens NR; Raposo AA; Basto R; St Johnston D; Raff JW. "From stem cell to embryo without centrioles.". (2007): http://europepmc.org/abstract/med/17716897.
    10.1016/j.cub.2007.07.060
Preprint
  1. Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; Paço, Susana; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. Corresponding author: Raposo, AASF. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". 2023. http://dx.doi.org/10.1101/2023.12.27.573411.
    10.1101/2023.12.27.573411
  2. Marta F. Fidalgo; Catarina G. Fonseca; Paulo Caldas; Alexandre A. S. F. Raposo; Tania Balboni; Ana R. Grosso; Francisca F. Vasconcelos; Cláudio A. Franco. "Alternative splicing changes are associated with pre-birth adaptation during lung development". 2022. https://doi.org/10.1101/2022.01.19.476886.
    10.1101/2022.01.19.476886
  3. Falcão, Ana Mendanha; Meijer, Mandy; Scaglione, Antonella; Rinwa, Puneet; Agirre, Eneritz; Liang, Jialiang; Larsen, Sara C.; et al. "PADI2-mediated citrullination is required for efficient oligodendrocyte differentiation and myelination". 2018. http://dx.doi.org/10.1101/425348.
    10.1101/425348

Intellectual property

Provisional application for patent
  1. 2023. "Genomic Mutations".
    Protected • 10.5281/zenodo.10684403.

Other

Software
  1. Raposo, AASF; Tiago João Carrilho Lima do Val. "ASAP - ATAC-Seq Automated Pipeline". Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes. This version was developed for iMM-LOBO HPC, with Slurm/Shifter.. 2023.
    https://zenodo.org/doi/10.5281/zenodo.10683658
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/24 Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells 15TH INTERNATIONAL SYMPOSIUM ON VARIANTS IN THE GENOME
HUGO - Human Genome Organisation (Póvoa de Varzim, Porto, Portugal)
2023/11/17 Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells 3rd Symposium of the National Research Infrastructure for Genome Sequencing and Analyisis (“GenomePT Symposium”)
National Institute of Health Doutor Ricardo Jorge (INSA) (Lisbon, Portugal)
2021/05/20 The signature of human regulatory CD4 thymocytes and its modulation by the chromatin landscape XLVI Annual Meeting of the Portuguese Society for Immunology
Portuguese Society for Immunology (online) (Portugal)
2020/10/14 The signature of human CD4 regulatory thymocytes and its modulation by the chromatin landscape 19th Biennial Meeting of the European Society for Immunodeficiencies
European Society for Immunodeficiencies (Birmingham, United Kingdom)
2019/09/20 Homeostasis of Human NaÏve CD4 T Cells: Changes in Transcriptomes of Regulatory or Conventional Cells Reveal Distinct Mechanisms of Maintenance Independent of Thymic Output 2019 Focused Meeting of the European Society for Immunodeficiencies - Malignancy and PID
European Society for Immunodeficiencies (Brussels, Belgium)
2018/10/25 Transcriptional Signature of Thymic-committed Human Regulatory T Cells 18th Biennial Meeting of the European Society for Immunodeficiencies
European Society for Immunodeficiencies (Lisbon, Portugal)
2015/10/10 selected abstract: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" 3rd Joint Meeting of the Societies for Developmental Biology SPBD (PT), SEBD (ES), and BSDB (UK)
Sociedade de Biologia do Desenvolvimento (Albufeira, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019/09/01 - 2021/11/30 Data Science Methods Applied to the Study of The Signature of Regulatory CD4 T Cells in the Human Thymus and its modulation by the Chromatin Landscape
Co-supervisor of Susana Maria Santos do Paço
 Mestrado em Métodos Analíticos Avançados (Master)
Instituto de Medicina Molecular, Portugal

Universidade Nova de Lisboa Instituto Superior de Estatística e Gestão de Informação, Portugal
2018 - 2019 Identification of novel potential therapeutic targets for T-cell Acute Lymphoblastic Leukemia
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2017 - 2018 Uncovering the regulatory T cell transcriptional signature in the human thymus
Supervisor of Miguel Ângelo Simão Dias
 Mestrado de Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/11/19 - 2024/11/19 Meeting of members of the Federated Human Data Community of the ELIXIR consortium
Meeting
 Elixir Federated Human Data Community F2F/hybrid meeting
ELIXIR Europe, United Kingdom

BioData.pt, Portugal
2024/11/07 - 2024/11/07 Symposium of the European Scientific Foundation for Laboratory Hemato-oncology (ESLHO)
Symposium
 13th ESLHO Symposium on Multi-omics approaches for diagnosis and monitoring of hematological malignancies.
European Scientific Foundation for Laboratory Hemato-oncology (ESLHO), Netherlands
2024/05/12 - 2024/05/12 Workshop preceding conference on the ACMG-AMP classification system, the UCSC recommended track set, HGVS Nomenclature and gene variant databases.
Workshop
 15th International Symposium on Variants in the Genome: Optional Workshop Day
Sociedade Portuguesa de Genética Humana, Portugal

Human Genome Organization (HUGO), United States
2016/10 - 2016/10 Poster presentation: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" Raposo AASF*, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DL, Ettwiller L, Flicek P, Crawford GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS
Conference
 Big Data in Biology and Health
EMBL Heidelberg Genome Biology, Germany
2016/09/01 - 2016/09/02 Poster presentation: "Functional Genomics of Neurogenesis: A crosstalk between Notch/RBPJ and Ascl1 Transcriptional pathways" Raposo AASF, Vasconcelos FF, Laranjeira C, Castro DS, EMBO Young Scientists' Forum 2016, 1-2 September 2016, Lisbon, Portugal
Meeting
 EMBO Young Scientists' Forum 2016
European Molecular Biology Organisation , Germany
2015/11/30 - 2015/12/03 Hands-on workshop on Translational Bioinformatics in Heath and Disease, from data mining of human genomic databases to drug discovery
Workshop
 TBHD15 Translational Bioinformatics in Heath and Disease
Instituto Gulbenkian de Ciência, Portugal
2015/09/28 - 2015/10/01 Hands-on workshop on Genomic Architecture of Complex Traits
Workshop
 GACT15 Genomic Architecture of Complex Traits
Instituto Gulbenkian de Ciência, Portugal
2015/06/04 - 2015/06/05 Poster presentation: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" Raposo AASF*, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DL, Ettwiller L, Flicek P, Crawford GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS,
Conference
 XIV Meeting of Portuguese Society for Neuroscience
Sociedade Portuguesa de Neurociências, Portugal
2013/09/14 - 2013/09/21 Workshop: tools/public data resources in neurogenomics and brain diseases. Mornings/evenings with lectures on areas in which large datasets are available, such as the synaptic complex, synaptic plasticity, mRNAs, neuro-ontology, neurogenomics, and neurogenesis. In the afternoons, students and lecturers worked to apply the new tools and datasets to answer specific research questions. By the end of the course we had six jointly written draft papers for each of the questions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341549
Workshop
 INCF short course on neuroinformatics, neurogenomics, and brain disease
International Neuroinformatics Coordinating Facility, Sweden
2012/10 - 2012/10 Poster presentation: "Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis" Raposo AASF*, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DL, Ettwiller L, Flicek P, Crawford GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS
Conference
 From Functional Genomics to Systems Biology
EMBL Heidelberg Genome Biology, Germany
2011/09/05 - 2011/09/09 Hands-on workshop on Microarray Data Analysis using R and Bioconductor
Workshop
 MDARB11 Microarray Data Analysis using R and Bioconductor
Instituto Gulbenkian de Ciência, Portugal
2011 - 2011 EMBL-European Bioinformatics Institute Workshop: Advanced Next-Generation Sequencing ChIP-seq Data analysis and European Nucleotide Archive database course.
Workshop
 Advanced Next-Generation Sequencing Bioinformatics
European Bioinformatics Institute, United Kingdom

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/10/22 Deciphering FOXO1-Mediated Gene Regulation Through Multi-Omics Integration http://hdl.handle.net/10362/174682
(Thesis) Main arguer
 FREDERICO DIAS ÁGUA (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/12/12 Computational Analysis of FoxO1-mediated transcriptome alterations in Endothelial cells
(Thesis) Main arguer
 Paulo Ricardo Viana Mendonça (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/11/07 Single-cell transcriptional landscape of circulating Tfh nd Treg cells in COVID-19 patients
(Thesis) Main arguer
 Diogo Martins Fonseca (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024/10/20 - 2024/11/21 Molecular Biology Reports (0301-4851) Springer Science+Business Media

Association member

Society Organization name Role
2023/10/10 - Current Sociedade Portuguesa de Genética Humana Member
2022/01/01 - Current ERN RITA – European Reference Network for Immunodeficiency, autoinflammatory and autoimmune diseases Participant
2022/01/01 - Current Co-Lab AccelBio https://accelbio.pt/ Participant
2020/01/01 - Current Estratégia Nacional para a Medicina Genómica - PT_MedGen iMM node representative
2018 - Current Sociedade Portuguesa de Imunologia member
2018 - Current European Society of Immunodeficiency member
2017/05/01 - Current Beyond One Million Genomes. A distributed genome sequencing and analysis infrastructure integrated in the Portuguese Roadmap of Research Infrastructures. It congregates over 50 researchers and technical personnel and amasses important bioinformatics expertise into a single genomics consortium. Participant in workgroup 6, "Health economics and outcome research"
2017/04/30 - Current GenomePT iMM node member
2021/10/06 - 2025/10/05 Mye-INFOBANK COST Action (European cooperation in Science and Technology) Converting molecular profiles of myeloid cells into biomarkers for inflammation and cancer Participant in Workgroup Mye-Matrix (Omics, data, computational biology)

Conference scientific committee

Conference name Conference host
2024/04/16 - 2024/04/19 Annual International (Bio)Medical Students Meeting - AIMS Meeting 2024 Medical School of the University of Lisbon
2023/11 - 2023/11 3rd Symposium of the National Research Infrastructure for Genome Sequencing and Analysis National Institute of Health Doutor Ricardo Jorge
2022/03/10 - 2022/03/13 AIMS Meeting 2022 Medical School of the University of Lisbon
2012/10/03 - 2012/10/05 HCist'2012 - International Conference on Health and Social Care Information Systems and Technology

Consulting

Activity description Institution / Organization
2010 - 2010 GoBusiness/FCT-UNL, "A stock market crash alarm system based on a Hurst Index Neural Network", 2010 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2001 - 2001 Training of Siemens SA clients in Management, Operation and Maintenance of Optical Networks and their equipment. Engineer level, to Vodafone and Portugal Telecom in Portugal; Airtel and Telefónica in Spain. Siemens SA, Portugal, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/11/13 - 2023/12/20 "Modelling multiomics data for Precision Medicine" Data Science and Engineering (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2009/11/23 - 2009/11/25 Basics of Neuroscience – first course 4.11. 2009 to 4.12.2009 Lectures and laboratorial work. Lecturers: Prof. Dr. Michael Kiebler, Dr. Georgia Vendra, Dr. Alexandre Raposo Neuronal Cell Biology (Magister) Medical University of Vienna Center for Brain Research, Austria
2009 - 2009 Advanced Neuronal Cell Biology Advanced Neuronal Cell Biology (Doktor (PhD)) Medical University of Vienna Center for Brain Research, Austria

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2012/05 Interview upon publication "Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila D-V Axis", Science, 2012: «Alexandre Raposo contribui para nova visão sobre o desenvolvimento da Drosophila» "CienciaHoje", a digital news outlet for science. Original URL broken.

Interview (tv / radio show)

Program Topic
2021/05/29 - Current Weekly show "Os Dias do Futuro", Antena 1 national radio (RTP), focused on science, researchers, and innovation. https://www.rtp.pt/play/p383/e548566/os-dias-do-futuro https://www.rtp.pt/programa/radio/p3000 My professional trajectory and research. Here I had the opportunity to describe my work on Precision Medicine at the IMM.
2012/10/15 - 2012/10/15 Antena 2 Ciência, interview to comment on Nobel Prize Physiology or Medicine 2012, given to Sir John Gurdon and S. Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent" O nobéis de medicina, física e química - o que pode mudar nas nossas vidas por causa do trabalho dos cientistas, agora galardoados.
2012/05/07 - 2012/05/07 Antena 2 Ciência: Os trabalhos e os dias dos cientistas e o que muda nas nossas vidas "Núcleo da Célula" (in PT). I was interviewed about my publication of "Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila D-V Axis" in Science, 2012 Nuclear migration and cell polarity

Journal scientific committee

Journal title (ISSN) Publisher
2022/10/10 - 2022/10/24 Immunology Letters (0165-2478) Elsevier

Mentoring / Tutoring

Topic Student name
2022/12/05 - 2023/12/15 Variant calling of Human Genomes in a High-Performance Computer cluster environment Maria Escórcio Brazão
2019/09/01 - 2020/09/01 Benchmarking of clustering algorithms for analysis of human CD4 T cell transcriptomes Susana Maria Santos do Paço
2017 - 2018 RNA-seq Data Analysis Francisca Ferreira Vasconcelos
2017 - 2017 Next Generation Sequencing Data Analysis Marta Ferreira
2017 - 2017 High-Performance Computer Cluster with SLURM/Docker Several users of the HPC cluster LOBO
Distinctions

Other distinction

2018 CEEC Assistant Researcher contract
Fundação para a Ciência e a Tecnologia, Portugal
2012 Fee waiver
European Molecular Biology Laboratory, Germany
2003 PhD Studentship
Fundação para a Ciência e a Tecnologia, Portugal
2002 PhD Biomedicine Programme studentship
Fundação Calouste Gulbenkian, Portugal
1996 Studentship
EU Framework Programme for Research and Innovation Euratom, Belgium