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Margarida Isabel Nascimento Vaz. Completed the Mestrado in Biomedicina Molecular in 2019 by Universidade de Aveiro Departamento de Ciências Médicas and Licenciatura in Ciências Biomédicas in 2017 by Universidade da Beira Interior Faculdade de Ciências da Saúde. Attends the Doutoramento in Biomedicine by Universidade de Aveiro since 2020/09. Is PhD scholarship supported by FCT - UI/BD/151354/2021 in Fundação para a Ciência e a Tecnologia. Published 5 articles in journals. Organized 2 event(s). Participated in 12 event(s). Has received 1 awards and/or honors. Participates and/or participated as Research Fellow in 1 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Neurosciences, Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism, Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Health-Related Biotechnology and Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology.
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Identification

Personal identification

Full name
Margarida Isabel Nascimento Vaz

Citation names

  • Vaz, Margarida

Author identifiers

Ciência ID
C218-3261-2649
ORCID iD
0000-0001-5425-1495

Email addresses

  • margaridavaz@ua.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2020/09 - 2024
Ongoing
 Biomedicine (Doutoramento)
Universidade de Aveiro, Portugal
2017 - 2019
Concluded
 Biomedicina Molecular (Mestrado)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
"Chemokines effect on kinases and phosphatases involved in Alzheimer’s disease pathology" (THESIS/DISSERTATION)
 18/20
2014 - 2017
Concluded
 Ciências Biomédicas (Licenciatura)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
 16/20
Affiliation

Science

Category
Host institution 		Employer
2020/09/01 - 2021/03/31 Researcher (Research) Universidade de Aveiro Instituto de Biomedicina, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal

Others

Category
Host institution 		Employer
2021/04/01 - Current PhD scholarship supported by FCT - UI/BD/151354/2021 Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
Projects

Grant

Designation Funders
2020/09/01 - Current Exosomes as Diagnostic Tools for Alzheimer´s Disease - EXO_DIAG_AD
2019-AARG-644347
Research Fellow
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Alzheimer's Association
Ongoing
Outputs

Publications

Conference poster
  1. Vaz, Margarida; Soares Martins, Tânia; da Cruz e Silva, Odete; Ana Gabriela Henriques. Corresponding author: Ana Gabriela Henriques. "Extracellular vesicles biogenesis and release are affected by Aß peptide". Paper presented in AD/PD 2024, 2024.
  2. Vaz, Margarida; Tânia Soares Martins; Odete da Cruz e Silva; Ana Gabriela Henriques. "FTIR analysis of neuronal-like cells upon Aß exposure". Paper presented in Alzheimer's Association International Conference, 2023.
    10.1002/alz.082671
  3. Vaz, Margarida; Tânia Soares Martins; Odete da Cruz e Silva; Ana Gabriela Henriques. "Aß effect in extracellular vesicles biogenesis and secretion". Paper presented in First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV), 2023.
  4. Vaz, Margarida; Tânia Soares Martins; Odete da Cruz e Silva; Ana Gabriela Henriques. "Biogenesis and secretion of extracellular vesicles upon Aß treatment". Paper presented in Workshop on “Novel Diagnosis Tools for Alzheimer's Disease”, 2023.
  5. Tânia Soares Martins; Beatriz Pinho; Dário Trindade; Vaz, Margarida; Ana Gabriela Henriques. "Exosomes signatures with putative diagnostic value for Alzheimer's disease". Paper presented in Workshop on “Novel Diagnosis Tools for Alzheimer's Disease”, 2023.
  6. Vaz, Margarida; Tânia Soares Martins; Odete da Cruz e Silva; Ana Gabriela Henriques. "Metabolic Profile of Neuronal-Like Cells Lines in Response to Aß Treatment.". Paper presented in VI iBiMED Symposium: From Fundamental Research to Clinical Practice., 2023.
  7. Vaz, Margarida; Tânia Soares Martins; Odete da Cruz e Silva; Alexandra Nunes; Ana Gabriela Henriques. "Aß EFFECT ON NEURONAL-LIKE CELLS’ METABOLIC PROFILE". Paper presented in AD/PD 2023, 2023.
  8. Vaz, Margarida; Trindade, Dário; Domingues, Catarina; da Cruz e Silva, Odete; Henriques, Ana Gabriela. "IL-8 and MCP-1 impact on kinases and phosphatases involved in Tau phosphorylation". Paper presented in Sinal 2019 - 10th Meeting in Signal Transduction, 2019.
Journal article
  1. Vaz, Margarida; Soares Martins, Tânia; Henriques, Ana Gabriela. "Extracellular vesicles in the study of Alzheimer's and Parkinson's diseases: Methodologies applied from cells to biofluids". Journal of Neurochemistry 163 4 (2022): 266-309. http://dx.doi.org/10.1111/jnc.15697.
    10.1111/jnc.15697
  2. Martins, Tânia Soares; Vaz, Margarida; Henriques, Ana Gabriela. "A review on comparative studies addressing exosome isolation methods from body fluids". Analytical and Bioanalytical Chemistry 415 7 (2022): 1239-1263. http://dx.doi.org/10.1007/s00216-022-04174-5.
    10.1007/s00216-022-04174-5
  3. Soares Martins, Tânia; Marçalo, Rui; Ferreira, Maria; Vaz, Margarida; Silva, Raquel M.; Martins Rosa, Ilka; Vogelgsang, Jonathan; et al. "Exosomal Aß-Binding Proteins Identified by “In Silico” Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease". International Journal of Molecular Sciences 22 8 (2021): 3933. http://dx.doi.org/10.3390/ijms22083933.
    Open access • Published • 10.3390/ijms22083933
  4. Vaz, Margarida; Domingues, Catarina; Trindade, Dário; Barra, Cátia; Oliveira, Joana M.; Rosa, Ilka M.; da Cruz e Silva, Odete A.B.; Henriques, Ana G.. "IL-8 and MCP-1 Impact on Tau Phosphorylation and Phosphatase Activity". Current Alzheimer Research 17 11 (2021): 985-1000. http://dx.doi.org/10.2174/1567205017666201130091129.
    Published • 10.2174/1567205017666201130091129
  5. Soares Martins, Tânia; Trindade, Dário; Vaz, Margarida; Campelo, Inês; Almeida, Martim; Trigo, Guilherme; da Cruz e Silva, Odete A. B.; Henriques, Ana Gabriela. "Diagnostic and therapeutic potential of exosomes in Alzheimer’s disease". Journal of Neurochemistry (2020): http://dx.doi.org/10.1111/jnc.15112.
    Published • 10.1111/jnc.15112
Thesis / Dissertation
  1. Vaz, Margarida. "Chemokines effect on kinases and phosphatases involved in Alzheimer’s disease pathology". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/07/13 Extracellular vesicles biogenesis and secretion in response to Aß Research Summit 2023
2022/07/15 Unravelling Abeta impact on exosome secretion and signal pathways relevant to Alzheimer’s disease pathogenesis Research Summit 2022

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/06/16 - 2023/06/17 Workshop on “Novel Diagnosis Tools for Alzheimer's Disease” (2023/06/16 - 2023/06/17)
Workshop (Member of the Organising Committee)
2018/11/20 - 2018/11/20 Signaling Afternoon - event about cell signaling whose focus was to show the importance of various signaling pathways in the most diverse areas of biomedicine and how they contribute to some pathologies. (2018/11/20 - 2018/11/20)
Seminar (Member of the Organising Committee)
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/03/08 - 2017/03/11 8ª Jornadas de Ciências Biomédicas na Faculdade das Ciências da Saúde da Universidade da Beira Interior (2017/03/08 - 2017/03/11)
Meeting (Other)
 Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/07/16 - 2023/07/20 Alzheimer's Association International Conference
Conference
2023/03/28 - 2023/04/01 AD/PD™ 2023 | Advances in Science & Therapy | Gothenburg, Sweden
Conference
2023/02/10 - 2023/02/11 2nd Symposium on Alzheimer's Disease: An Update on Pathology and Therapeutics
Symposium
2022/03/02 - 2022/03/02 New methodologies for diagnosing Alzheimer's disease from blood
Round table
 New methodologies for diagnosing Alzheimer's disease from blood
Universidade de Aveiro, Portugal
2022/02/23 - 2022/02/23 MEDISIS open day 2022
Conference
 MEDISIS open day 2022
Universidade de Aveiro Instituto de Biomedicina, Portugal
2021/09/13 - 2021/09/14 First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
Conference
 First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/07/26 - 2021/07/30 Alzheimer's Association International Conference - AAIC 2021
Conference
 Alzheimer's Association International Conference - AAIC 2021
Alzheimer's Association, United States
2021/07/09 - 2021/07/09 UA Research summit - 2021
Conference
 UA Research summit - 2021
Universidade de Aveiro, Portugal
2020/12/18 - 2020/12/18 First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
Conference
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/03/29 - 2019/03/29 XPERiMENTA Universidade de Aveiro - participated in the activity developed by the Neuroscience and Signaling group within the scope of the Exhibition of the Department of Medical Sciences.
Workshop
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019/03/13 - 2019/03/13 Semana Internacional do Cérebro - Visit to a primary school in Aveiro where she participated in the various didactic activities that were carried out with students about the brain, its functions and its importance in our daily lives.
Workshop
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016/03/10 - 2016/03/10 7ª Jornadas de Ciências Biomédicas na Universidade de Aveiro
Meeting
Universidade de Aveiro, Portugal
2015/03/12 - 2015/03/14 6ª Jornadas de Ciências Biomédicas no Campus da Gambelas da Universidade do Algarve
Meeting
Universidade do Algarve - Campus de Gambelas, Portugal

Association member

Society Organization name Role
2015 - 2016 Start Up Resarch - volunteer group, consisting of students of Biomedical Sciences from the University of Beira Interior that aims to: learning laboratory techniques; discussion of scientific topics; conducting scientific mini-projects; organization of the Summer University - Health and Research. The scientific activities developed were: mini-course in advanced reproduction; electronic microscopy; magnetic resonance; automatic sequencing. Active member

Mentoring / Tutoring

Topic Student name
2021/09/01 - 2022/02/28 Laboratorial tutor of a MSc student in Molecular and Cell Biology Ema Figueiredo
2021/03/01 - 2021/07/31 Laboratorial tutor of a BSc student in Biomedical Engineering Sara Pereira
Distinctions

Other distinction

2017 Certificado de Mérito
Universidade da Beira Interior, Portugal