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Doutora em Biofísica Molecular pela UNESP de São José do Rio Preto, Brasil, (2015) com estágio DAAD no German Research School for Simulation Sciences, Forschungszentrum Jülich, na Alemanha. Possui graduação em Física Biológica (2007) e mestrado em Biofísica Molecular (2010) também pela UNESP de São José do Rio Preto. Durante o doutorado trabalhou principalmente em dinâmica molecular clássica, dinâmica molecular ab initio (Car-Parrinello) e métodos híbridos (QM/MM) aplicados ao estudo de catálise enzimática. Foi pós-doutoranda do Programa de Genética e Biologia Molecular na Universidade Federal de Goiás (UFG-Goiânia) e atuou na Rede Centro-Oeste de Formação e Pesquisa em Biologia Computacional junto ao Núcleo Colaborativo de Biossistemas (UFG-Jataí), com projetos incluindo virtual screening de produtos naturais e biologia de sistemas. Atualmente é pós-doutoranda na área de Bioinformática do Centro de Pesquisa de Oncologia Molecular no Hospital de Cancer de Barretos. Atua principalmente na análise de dados de expressão de mRNA e miRNA provenientes da plataforma NanoString e implementação de interface gráfica para ferramentas de diagnóstico molecular em Galaxy server. Possui experiência em R e clusters de alta performance. Contato: lsussuchi@gmail.com.
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Identification

Personal identification

Full name
Sussuchi da Silva Luciane

Citation names

  • Sussuchi, Luciane
  • da Silva, LS

Author identifiers

Ciência ID
C31C-9882-435B
ORCID iD
0000-0002-7470-4655

Addresses

  • Molecular Oncology Research Center, Rua Antenor Duarte Viléla, 1331, 14784-400, São Paulo, Barretos, Brazil (Professional)

Knowledge fields

  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Exact Sciences - Physical Sciences - Molecular Physics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2)
Education
Degree Classification
2015/09/01
Concluded
 Biofísica Molecular (Doctor of Philosophy)
Major in Biofísica Molecular Computacional
Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de São José do Rio Preto, Brazil
2010/03/01
Concluded
 Biofísica Molecular (Master Universitario)
Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de São José do Rio Preto, Brazil
2007/06/01
Concluded
 Física Biológica (Bachelor)
Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de São José do Rio Preto, Brazil
Affiliation

Science

Category
Host institution 		Employer
2018/02/01 - Current Postdoc (Research) Hospital de Amor, Brazil
2016/04/01 - Current Postdoc (Research) Universidade Federal de Goiás, Brazil
Outputs

Publications

Conference abstract
  1. Luciane, Sussuchi. "P1.03-13 Genomic Landscape of Brazilian Non-Small Cell Lung Cancer". 2019.
    10.1016/j.jtho.2019.08.865
  2. Luciane, Sussuchi. "P2.03-07 Frequency of Driver Genes (EGFR, KRAS, BRAF, ALK, RET and ROS1) Alterations in Brazilian Patients with Lung Adenocarcinoma". 2019.
    10.1016/j.jtho.2019.08.1454
  3. Luciane, Sussuchi. "Evaluation of inductor factors in the epithelial-mesenchymal transition (EMT) in testicular germ cell tumours (TGCT) and their roles in cisplatin resistance". 2019.
    10.1016/s1569-9056(19)32542-4
Conference poster
  1. Luciane, Sussuchi. "Implementation of machine learning algorithms for medulloblastoma classification in a local galaxy server". 2018.
    10.7490/F1000RESEARCH.1115815.1
Journal article
  1. Sussuchi, Luciane. "Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide". Journal of Neuro-Oncology (2021): http://dx.doi.org/10.1007/s11060-020-03675-6.
    10.1007/s11060-020-03675-6
  2. Sussuchi, Luciane. "Simultaneous analysis of ALK, RET, and ROS1 gene fusions by NanoString in Brazilian lung adenocarcinoma patients.". Translational lung cancer research (2021): https://europepmc.org/articles/PMC7867767.
    10.21037/tlcr-20-740
  3. Sussuchi, Luciane. "Cell-free DNA promotes malignant transformation in non-tumor cells". Scientific Reports (2020): http://dx.doi.org/10.1038/s41598-020-78766-5.
    10.1038/s41598-020-78766-5
  4. Sussuchi, Luciane. "Whole blood mRNA expression-based targets to discriminate active tuberculosis from latent infection and other pulmonary diseases". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-78793-2.
    10.1038/s41598-020-78793-2
  5. Sussuchi, Luciane. "Expression of GNAS, TP53, and PTEN Improves the Patient Prognostication in SHH Medulloblastoma Subgroup". The Journal of Molecular Diagnostics (2020): http://dx.doi.org/10.1016/j.jmoldx.2020.04.207.
    10.1016/j.jmoldx.2020.04.207
  6. Weder Pereira de Menezes; Viviane Aline Oliveira Silva; Izabela Natália Faria Gomes; Marcela Nunes Rosa; Maria Luisa Corcoll Spina; Adriana Cruvinel Carloni; Ana Laura Vieira Alves; et al. "Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness". Cells 9 2 (2020): 492-492. https://doi.org/10.3390/cells9020492.
    10.3390/cells9020492
  7. Luciane, Sussuchi. "Identification of a new antifungal compound against isocitrate lyase of Paracoccidioides brasiliensis". Future Microbiology (2019): http://dx.doi.org/10.2217/fmb-2019-0166.
    10.2217/fmb-2019-0166
  8. Ricardo Lemes Gonçalves; Gabriela de Lima Menezes; Luciane Sussuchi; Marcos Lázaro Moreli; Melina Mottin; Carolina Horta Andrade; Maristela Pereira; Roosevelt Alves da Silva. "Dynamic behavior of Dengue and Zika viruses NS1 protein reveals monomer–monomer interaction mechanisms and insights to rational drug design". Journal of Biomolecular Structure and Dynamics (2019): 1-11. https://doi.org/10.1080/07391102.2019.1677504.
    10.1080/07391102.2019.1677504
  9. Luciane, Sussuchi. "Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D". Journal of Cellular Biochemistry (2017): http://dx.doi.org/10.1002/jcb.25678.
    10.1002/jcb.25678
  10. Luciane, Sussuchi. "Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D". Current Protein & Peptide Science (2015): http://dx.doi.org/10.2174/1389203716666150505231625.
    10.2174/1389203716666150505231625