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RICARDO JORGE PIMENTEL SOARES DOS REIS. Concluiu o(a) Mestrado em Mestrado Integrado em Medicina em 2013/07 pelo(a) Universidade do Porto Faculdade de Medicina. Frequenta o(a) Doutoramento em Neurociências pelo(a) Universidade do Porto Faculdade de Medicina. É Assistente no(a) Centro Hospitalar Universitário de São João e Assistente Convidado no(a) Universidade do Porto Faculdade de Medicina. Publicou 19 artigos em revistas especializadas. Orientou 1 dissertação(ões) de mestrado. Recebeu 1 prémio(s) e/ou homenagens. Participa e/ou participou como Investigador em 2 projeto(s) e Investigador responsável em 1 projeto(s). Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Medicina Clínica com ênfase em Neurologia Clínica, Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Neurociências e Ciências Médicas e da Saúde com ênfase em Ciências da Saúde com ênfase em Epidemiologia. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: desenvolvimento do sistema nociceptivo; Prrxl1; Factor de transcrição do tipo homeodomain; Promotor alternativo; .
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Identification

Personal identification

Full name
RICARDO JORGE PIMENTEL SOARES DOS REIS

Citation names

  • Reis, Ricardo
  • Soares-dos-Reis, Ricardo
  • Soares dos Reis, Ricardo

Author identifiers

Ciência ID
C41C-4691-79E4
ORCID iD
0000-0001-6878-8568

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Health Sciences - Epidemiology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2015/10 - 2022/12
Ongoing
 Neurociências (Doutoramento)
Major in Área de especialidade: Neurociências Experimentais
Universidade do Porto Faculdade de Medicina, Portugal
"Nonconventional biomarkers in multiple sclerosis" (THESIS/DISSERTATION)
2015/02 - 2017/02
Concluded
 Clinical Scholars Research Training (Pós-Graduação)
Harvard Medical School, United States
2013/07
Concluded
 Mestrado Integrado em Medicina (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
"Identification and functional study of PRRXL1 phosphorylation sites" (THESIS/DISSERTATION)
 17
2007/07
Concluded
 Ciências e Tecnologias (Ensino secundário)
Escola Secundária de Monserrate, Portugal
 20
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2019/09 - Current Invited Assistant (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2017/10 - 2018/01 Invited Assistant (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2013/09 - 2014/09 Tutor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal

Other Careers

Category
Host institution 		Employer
2020/10/12 - Current Assistente (Médica) Centro Hospitalar Universitário de São João, Portugal
2014/01/01 - 2020/10/12 Interno (Médica) Centro Hospitalar Universitário de São João, Portugal
Projects

Grant

Designation Funders
2022/09 - 2024/08 MSense a miniaturized biosensor technology for personalized diagnostics and monitoring of multiple sclerosis
COTEC | Alfredo da Silva
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação Amélia de Mello
Ongoing

Contract

Designation Funders
2017/02 - Current Feasibility of developing serum NfL assay on a point-of-care immunosensor platform
PT-MSG-11588
Principal investigator
Centro Hospitalar Universitário de São João, Portugal
 Biogen Portugal
Ongoing
2022/01/01 - 2023/06/30 Aumentando a captação de Vitamina C pela microglia para melhorar a Doença de Alzheimer
EXPL/MED-NEU/0588/2021
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
LA/P/0070/2020
10.54499/LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Mecanismos moleculares que modulam a acção do Prrxl1 no desenvolvimento dos neurónios nociceptivos
PTDC/SAU-OBD/099886/2008
Researcher
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2018/06 - 2021/01 EVT-PT: Caraterização do acesso à trombectomia mecânica em Portugal
sem referencia
Researcher
Centro Hospitalar Universitário de São João, Portugal
 Sociedade Portuguesa do AVC
Concluded
Outputs

Publications

Book chapter
  1. Castro, P.; Soares-Dos-reis, R.. "Ischemic Stroke in the ICU: Bedside Monitoring of the Cerebral Autoregulation Status by Transcranial Doppler (TCD/TCCS) in the Acute Stage". 581-591. 2021.
Conference abstract
  1. Soares dos Reis, Ricardo; Vieira, Sara; Sá, MJ. "Where Parkinson meets Charcot: a clinical report". Paper presented in 4th International Porto Congress of Multiple Sclerosis, Porto, 2017.
    Published
Conference paper
  1. Cruz, Andrea; Queirós, Raquel; Abreu, Catarina; Barata, Catarina; Fernandes, Rosa; Silva, Rufino; Ambrósio, António; et al. Corresponding author: Mendes Pinto, Inês. "Electrochemical-based sensing device for the detection of inflammatory cytokines". Paper presented in MNE2017 - 43rd International Conference on Micro and Nanoengineering, Braga, Portugal, 2017.
    Published
Conference poster
  1. Soares-dos-Reis, Ricardo; Moreira, Daniel; Carvalho, Duarte; Santos, Evelyn; Neves, Miguel; Mendes Pinto, Inês. Corresponding author: Mendes Pinto, Inês. "MSense: a miniaturized biosensor technology for personalized diagnostics and monitoring of multiple sclerosis". Paper presented in Biosensors 2023, 33rd Anniversary World Congress on Biosensors, South Korea, 2023.
  2. Santos, Evelyn; Carvalho, Duarte Nuno ; Moreira, Daniel; Soares-dos-Reis, Ricardo; Bettencourt Relvas, João; Neves, Miguel; Mendes Pinto, Inês. Corresponding author: Mendes Pinto, Inês. "A Miniaturized Point-of-Care Biosensor as a Precise Molecular Analysis Tool for Monitoring Neurodegeneration". Paper presented in 15th Biennial ISN Satellite Meeting on Myelin Biology, Portugal, 2023.
  3. Soares dos Reis, Ricardo; Vieira, Sara; Sá, MJ. "Where Parkinson meets Charcot: a clinical report. 4th International Porto Congress of Multiple Sclerosis". Paper presented in 4th International Porto Congress of Multiple Sclerosis, 2017.
Journal article
  1. Fernandes, André Aires; Neves, Ana Lídia; Ferro, Daniela; Seabra, Mafalda; Mendonça, Teresa; Soares-dos-Reis, Ricardo; Sá, Maria José; Guimarães, Joana; Abreu, Pedro. "Clinical and analytical monitoring of patients with multiple sclerosis on anti-CD20 therapeutics: a real-world safety profile study". Frontiers in Neurology 15 (2025): https://doi.org/10.3389/fneur.2024.1500763.
    10.3389/fneur.2024.1500763
  2. Cardoso, D.; Bezerra, S.; Soares-dos-Reis, R.; Sá, M.J.; Guimarães, J.. "Optic neuropathy diagnosis in the emergency room - retrospective observational study of the last 18 years". European Journal of Ophthalmology 34 1 (2024): 267-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-85163016384&partnerID=MN8TOARS.
    10.1177/11206721231173005
  3. Margarida Ribeiro; Joana Oliveira; Jorge Meira; Ricardo Soares-dos-Reis; Maria Luís Silva; Luís Albuquerque; Fernando Falcão-Reis; João Barbosa-Breda. "When a Red Eye Is a Red Flag: A Nontraumatic Case of a Direct Carotid-Cavernous Fistula". Journal of Neuro-Ophthalmology (2023): http://dx.doi.org/10.1097/wno.0000000000001847.
    10.1097/wno.0000000000001847
  4. Ferreira, F.; Ferreira, D.; Guimarães, J.; Soares-dos-Reis, R.. "Recurrent encephalopathy associated with pegylated beta-interferon treatment". Journal of Neuroimmunology 376 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85147203722&partnerID=MN8TOARS.
    10.1016/j.jneuroim.2023.578037
  5. Silva AS; Guimarães J; Sousa C; Mendonça L; Soares-Dos-Reis R; Mendonça T; Abreu P; Sequeira L; Sá MJ. "Metabolic syndrome parameters and multiple sclerosis disease outcomes: A Portuguese cross-sectional study.". Multiple sclerosis and related disorders (2022): http://europepmc.org/abstract/med/36401965.
    10.1016/j.msard.2022.104370
  6. Martins AI; Soares-Dos-Reis R; Jorge A; Duque C; Pereira DJ; Fontes Ribeiro C; Sargento-Freitas J; et al. "A 6-month trial of memantine for nystagmus and associated phenomena in oculopalatal tremor.". Frontiers in neurology (2022): http://europepmc.org/abstract/med/36061989.
    10.3389/fneur.2022.921341
  7. Vilares-Morgado R; Nunes HMM; Dos Reis RS; Barbosa-Breda J. "Management of ocular arterial ischemic diseases: a review.". Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2022): http://europepmc.org/abstract/med/35838806.
    10.1007/s00417-022-05747-x
  8. Dias R; Dos Reis RS; de Sousa SP; Rocha AF; Ribeiro AM; Almeida J. "Cerebral venous thrombosis in a young asymptomatic COVID-19 patient.". Porto biomedical journal (2022): http://europepmc.org/abstract/med/36186117.
    10.1097/j.pbj.0000000000000165
  9. Pedro, T.; Maia, R.; Costa, R.; Martins, B.; Ribeiro, J.; Domingues, R.; Brito, T.; et al. "Superior Cerebellar Artery Dissection in a Patient Diagnosed with Reversible Cerebral Vasoconstriction Syndrome: A Case Report,Disseção da Artéria Cerebelosa Superior numa Doente Diagnosticada com Síndrome de Vasoconstrição Cerebral Reversível: Um Caso Clínico". Sinapse 22 4 (2022): 169-172. http://www.scopus.com/inward/record.url?eid=2-s2.0-85152370822&partnerID=MN8TOARS.
    10.46531/sinapse/CC/220056/2022
  10. Dias MC; Dos Reis RS; Santos JV; Nunes AP; Ferreira P; Maia B; Fragata I; et al. "Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal.". Acta medica portuguesa (2021): http://europepmc.org/abstract/med/34499849.
    Accepted • 10.20344/amp.15031
  11. Ricardo Soares-dos-Reis; Jessica Li Tsz-Ching; Su-Hyun Kim; Anu Jacob; Daniel Whittam; Emeline Berthelot; Friedemann Paul; et al. "Asian and African/Caribbean AQP4-NMOSD patient outcomes according to self-identified race and place of residence". Multiple Sclerosis and Related Disorders 53 (2021): 103080-103080. https://doi.org/10.1016/j.msard.2021.103080.
    10.1016/j.msard.2021.103080
  12. Verónica Cabreira; Pedro Abreu; Ricardo Soares-dos-Reis; Joana Guimarães; Maria José Sá. "Multiple Sclerosis, Disease-Modifying Therapies and COVID-19: A Systematic Review on Immune Response and Vaccination Recommendations". Vaccines 9 7 (2021): 773-773. https://doi.org/10.3390/vaccines9070773.
    10.3390/vaccines9070773
  13. Leonor Dias; Ricardo Soares-dos-Reis; João Meira; Diana Ferrão; Pedro Ribeirinho Soares; Ana Pastor; Guilherme Gama; et al. "Cerebral Venous Thrombosis after BNT162b2 mRNA SARS-CoV-2 vaccine". Journal of Stroke and Cerebrovascular Diseases (2021): https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105906.
    10.1016/j.jstrokecerebrovasdis.2021.105906
  14. Sá MJ; Soares Dos Reis R; Altintas A; Celius EG; Chien C; Comi G; Graus F; et al. "State of the Art and Future Challenges in Multiple Sclerosis Research and Medical Management: An Insight into the 5th International Porto Congress of Multiple Sclerosis.". Neurology and therapy (2020): http://europepmc.org/abstract/med/32666470.
    10.1007/s40120-020-00202-7
  15. Ferraz, Beatriz; Reis, Ricardo; Rocha, Ana Luísa Carvalho; Moreira, Goreti; Fonseca, Luísa; Parreira, Tiago; Azevedo, Elsa; Castro, Pedro. "Prognostic yield of imaging before and after recanalization treatments in ischemic stroke". Acta Neurologica Scandinavica 141 3 (2020): 226-235. http://dx.doi.org/10.1111/ane.13208.
    10.1111/ane.13208
  16. Carolina Soares; Maria do Carmo Vilas-Boas; Elodie Murias Lopes; Hugo Choupina; Ricardo Soares-dos-Reis; Diogo Fitas; João Paulo Silva Cunha; et al. "Automated and objective measures of gait dynamics in camptocormia Parkinson’s Disease subthalamic deep brain stimulation". Clinical Neurology and Neurosurgery 186 (2019): 105537-105537. https://doi.org/10.1016/j.clineuro.2019.105537.
    10.1016/j.clineuro.2019.105537
  17. Luís Braz; Ricardo Soares-dos-Reis; Mafalda Seabra; Fernando Silveira; Joana Guimarães. "Brody disease: when myotonia is not myotonia". Practical Neurology 19 5 (2019): 417-419. https://doi.org/10.1136/practneurol-2019-002224.
    10.1136/practneurol-2019-002224
  18. Soares-Dos-Reis R; Messina S. "Cautious Interpretation of Observational Data.". JAMA neurology (2019): http://europepmc.org/abstract/med/31609379.
    10.1001/jamaneurol.2019.3456
  19. Leitão L; Soares-Dos-Reis R; Neves JS; Baptista RB; Bigotte Vieira M; Mc Causland FR. "Intensive Blood Pressure Treatment Reduced Stroke Risk in Patients With Albuminuria in the SPRINT Trial.". Stroke (2019): http://europepmc.org/abstract/med/31637971.
    10.1161/strokeaha.119.026316
  20. Soares MI; Soares-Dos-Reis R; Rosas MJ; Monteiro P; Massano J. "Intraoperative microelectrode recording in Parkinson's disease subthalamic deep brain stimulation: Analysis of clinical utility.". Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia (2019): http://europepmc.org/abstract/med/31416732.
    10.1016/j.jocn.2019.08.021
  21. Cruz A; Queirós R; Abreu CM; Barata C; Fernandes R; Silva R; Ambrósio AF; et al. "Electrochemical Immunosensor for TNFa-Mediated Inflammatory Disease Screening.". ACS chemical neuroscience (2019): http://europepmc.org/abstract/med/30985099.
    10.1021/acschemneuro.9b00036
  22. Ricardo Soares-dos-Reis; Ana Inês Martins; Ana Brás; Anabela Matos; Conceição Bento; João Lemos. "Ocular neuromyotonia". Practical Neurology 18 5 (2018): 389-390. https://doi.org/10.1136/practneurol-2017-001866.
    10.1136/practneurol-2017-001866
  23. Vasques-Nóvoa F; Laundos TL; Cerqueira RJ; Quina-Rodrigues C; Soares-Dos-Reis R; Baganha F; Ribeiro S; et al. "MicroRNA-155 Amplifies Nitric Oxide/cGMP Signaling and Impairs Vascular Angiotensin II Reactivity in Septic Shock.". Critical care medicine (2018): http://europepmc.org/abstract/med/29979224.
    10.1097/ccm.0000000000003296
  24. Abreu CM; Soares-Dos-Reis R; Melo PN; Relvas JB; Guimarães J; Sá MJ; Cruz AP; Mendes Pinto I. "Emerging Biosensing Technologies for Neuroinflammatory and Neurodegenerative Disease Diagnostics.". Frontiers in molecular neuroscience (2018): http://europepmc.org/abstract/med/29867354.
    10.3389/fnmol.2018.00164
  25. Soares-Dos-Reis, R.; Sofia Pessoa, A.; Dias, A.F.; Falcão, M.; Matos, M.R.; Vitorino, R.; Monteiro, F.A.; Lima, D.; Reguenga, C.. "A role for prolyl isomerase PIN1 in the phosphorylation-dependent modulation of PRRXL1 function". Biochemical Journal 474 5 (2017): 683-697. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014580896&partnerID=MN8TOARS.
    10.1042/BCJ20160560
  26. Soares-dos-Reis, Ricardo. "Spinal cord imaging in spastic paraparesis: are we cutting it thin enough?". International Journal of Clinical Neurosciences and Mental Health 3 Suppl.1 (2016): S19.
    Open access • Published • 10.21035/ijcnmh.2016.3(Suppl.1).S19
  27. Soares-dos-Reis, Ricardo. "Autoimmune polyglandular syndrome: coincidental or multiple sclerosis mimic?". International Journal of Clinical Neurosciences and Mental Health 3 Suppl.3 (2016): S05.
    Open access • Published • 10.21035/ijcnmh.2016.3(Suppl.3).S05
  28. Regadas, I.; Soares-dos-Reis, R.; Falcão, M.; Matos, M.R.; Monteiro, F.A.; Lima, D.; Reguenga, C.. "Dual role of Tlx3 as modulator of Prrxl1 transcription and phosphorylation". Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1839 11 (2014): 1121-1131. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907484335&partnerID=MN8TOARS.
    10.1016/j.bbagrm.2014.08.007
  29. Soares-Dos-Reis, R.; Pessoa, A.S.; Matos, M.R.; Falcão, M.; Mendes, V.M.; Manadas, B.; Monteiro, F.A.; Lima, D.; Reguenga, C.. "Ser119 phosphorylation modulates the activity and conformation of PRRXL1, a homeodomain transcription factor". Biochemical Journal 459 3 (2014): 441-453. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898656809&partnerID=MN8TOARS.
    10.1042/BJ20131014
  30. Pessoa A; Soares-dos-Reis R; Falcão M; Matos M; Monteiro C; Monteiro F; Reguenga C; Lima D. "Modulation of Prrxl1 transcriptional activity by phosphorylation.". (2012): http://europepmc.org/abstract/PMC/PMC3426046.
  31. Soares-dos-Reis R; Freitas J; Costa-Pereira A. "Incidence, costs and outcomes of avoidable hospitalizations in a southern European country: is there room for improvement?". (2012): http://europepmc.org/abstract/PMC/PMC3426026.

Intellectual property

Patent
  1. Mendes Pinto, Inês; Neves, Miguel; Santos, Evelyn; Bettencourt Relvas, João; Soares-dos-Reis, Ricardo. 2023. "Miniaturized ultrasensitive point-of-case biosensor for minimally invasive and quantitative molecular profile of neurodegeneration. PT01 118565". Portugal.
    Pending
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2018 - 2020 Influence of infarct location on the clinical outcome in patients who have suffered anterior circulation ischemic stroke
Supervisor
 Medicina (Master)
Universidade do Minho Escola de Medicina, Portugal
Distinctions

Award

2018 1st Prize Oral communication
Sociedade Portuguesa do AVC, Portugal