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Fabio Rocha Formiga graduated in Pharmaceutical Sciences, obtaining his bachelor¿s degree in 2004 from the Federal University of Rio Grande do Norte in Brazil, where he also concluded a master¿s course in Health Sciences. In 2011, he obtained a PhD in pharmaceutical technology from the University of Navarra in Spain, with distinctions, as a MAEC-AECID scholar. In 2018, he completed a research training in nanobiomaterials at the Rice University (Houston, USA). Dr. Formiga has worked as a Visiting Professor at the University of Coimbra, Portugal. He has experience in teaching/supervision at the BSc, MSc, PhD and postdoctoral levels. In addition, he has acted as referee for national and foreign funding agencies. He has participated as member of university committees, examining boards and has organized scientific meetings. Dr. Formiga has also been strongly involved in collaborative programs for exchange with European universities (from Portugal, Spain and Denmark). Co-founder and vice-President of the Brazilian Chapter of Controlled Release Society (CRS, 2019-present). He serves editorial board of peer-reviewed qualified journals, including the Frontiers in Medical Technology (Frontiers), Pharmaceutics (MDPI) and Drug Delivery and Translational Research (Springer). He is a member of the Brazilian Association of Pharmaceutical Sciences (ABCF) and the European Foundation for Clinical Nanomedicine (CLINAM). Currently, Dr. Formiga is a research scientist and Head of the Department of Immunology at the Aggeu Magalhães Institute, Oswaldo Cruz Foundation (FIOCRUZ) in Brazil. He also holds a tenured adjunct professor position at the Faculty of Medical Sciences of the University of Pernambuco (FCM/UPE). Dr. Formiga was acknowledged with the Research Award from Spanish Society of Pharmaceutics and Pharmaceutical Technology (SEFIG) in 2013 and the Benjamin Gilbert Award from FIOCRUZ in 2017. His research has focused on pharmaceutics, drug delivery and nanotechnology towards neglected diseases and regenerative medicine.
Identification

Personal identification

Full name
FABIO ROCHA FORMIGA

Citation names

  • FORMIGA, FABIO
  • Formiga, F.R.
  • Fabio Rocha Formiga

Author identifiers

Ciência ID
C610-F1F3-3EE0
ORCID iD
0000-0003-1553-0533
Scopus Author Id
55400495600

Email addresses

  • fabio.formiga@upe.br (Professional)

Telephones

Telephone
  • (+55) 8121012559 (Professional)

Addresses

  • Oswaldo Cruz Foundation (FIOCRUZ), Aggeu Magalhães Institute. Av. Professor Moraes Rego, 50740-465, Recife, PE, Brazil (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
Spanish; Castilian Proficiency (C2) Proficiency (C2) Advanced (C1) Proficiency (C2) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2018/08/09 - 2018/08/12
Concluded
Advances in Tissue Engineering (Postgraduate Certificate)
Rice University, United States
2007/11/01 - 2011/12/15
Concluded
Doctorado en Biofarmacia, Farmacologia y Calidad de Medicamentos (Doctor)
Universidad de Navarra Departamento de Tecnología y Química Farmacéuticas, Spain
"Growth factor loaded-microparticles as a tool for cardiac repair" (THESIS/DISSERTATION)
2005/03/01 - 2007/05/01
Concluded
Ciências da Saude (Master)
Universidade Federal do Rio Grande do Norte Centro de Ciências da Saúde, Brazil
"INFLUÊNCIA DE FÁRMACOS LIPOFÍLICOS NA ESTABILIDADE DE EMULSÕES DE USO TERAPÊUTICO" (THESIS/DISSERTATION)
1999/03/01 - 2004/06/01
Concluded
Farmácia (Bachelor)
Universidade Federal do Rio Grande do Norte Centro de Ciências da Saúde, Brazil
Affiliation

Science

Category
Host institution
Employer
2014/11/24 - Current Principal Investigator (Research) Fundação Oswaldo Cruz, FIOCRUZ, Instituto Aggeu Magalhães, Brazil
Fundação Oswaldo Cruz, FIOCRUZ, Instituto Aggeu Magalhães, Brazil

Teaching in Higher Education

Category
Host institution
Employer
2017/09/20 - Current Visiting Professor (University Teacher) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/12/20 - Current Associate Professor (University Teacher) Universidade de Pernambuco, Brazil
2008/03/01 - 2011/09/30 Tutor (University Teacher) Universidad de Navarra Facultad de Farmacia y Nutrición, Spain
Projects

Grant

Designation Funders
2020/07/01 - Current Evaluation of SARS-CoV-2 filtration and inactivation efficiency in N95 respirator with filter element containing nanoparticles
Inova
Principal investigator
Fundação Oswaldo Cruz, FIOCRUZ, Instituto Aggeu Magalhães, Brazil
Ongoing

Contract

Designation Funders
2020/08/01 - Current Repositioning of ivermectin for Covid-19: Development of an inhalation formulation from nanoaggregates (nano-embedded microparticles)
Principal investigator
Fundação Oswaldo Cruz, FIOCRUZ, Instituto Aggeu Magalhães, Brazil

Empresa Brasileira de Pesquisa Agropecuária, Brazil

Universidade de Pernambuco, Brazil
Fundação Oswaldo Cruz
Ongoing
2019/03/01 - 2021/03/01 Nanotecnologia aplicada ao desenvolvimento de novos larvicidas para o controle do Aedes aegypti
3631545903
Principal investigator
Fundação Oswaldo Cruz
2018/06/01 - 2020/02/01 Formulações inovadoras de base natural para o controle do Aedes aegypti nas regiões Iberoamericanas
88881.156340/2017-01
Researcher
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação para a Ciência e a Tecnologia
2016/06/01 - 2019/03/01 Nanoformulações de fatores de crescimento para regeneração cardiovascular
0018/2016
Principal investigator
Centro de Pesquisas Gonçalo Moniz, Brazil

Fundação Oswaldo Cruz, FIOCRUZ, Instituto Aggeu Magalhães, Brazil
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado da Bahia
Concluded
2017/03/01 - 2018/09/01 Nanotecnologia aplicada a terapia celular como estratégia para regeneração miocárdica
PIAP17
Principal investigator

Other

Designation Funders
2019/06/01 - Current LeishDerm: Topical formulation for adjuvant treatment of cutaneous leishmaniasis
Fiocruz
Researcher
Fundação Oswaldo Cruz, Brazil
Ongoing
Outputs

Publications

Book
  1. Formiga, F.R.; Patricia Severino; Inamuddin. Applications of Nanobiotechnology for Neglected Tropical Diseases. San Diego, United States: Elsevier. 2021.
    Published • Editor
Book chapter
  1. Formiga, F.R.. "Molecular Modification of Levan and Biotechnological Applications of its Derivatives". 2019.
    10.21775/9781912530267.10
Conference paper
  1. Formiga, F.R.. "Overexpression of the kinase Jean3 from Leishmania major may attenuate parasites infectivity in Balb/C mice by imparing the Th2-type immune response through the downregulation of IL4, IL10, and Arg1". 2019.
    10.4269/ajtmh.abstract2019
Edited book
  1. Formiga, F.R.. E-Book 22nd International Symposium on Microencapsulation. Brazil: ISBN 978-6-50-001292-7. 2020.
    Published • Editor
Journal article
  1. "Wild Passiflora (Passiflora spp.) seed oils and their nanoemulsions induce proliferation in HaCaT keratinocytes cells". Journal of Drug Delivery Science and Technology (2021): 102803-102803. http://dx.doi.org/10.1016/j.jddst.2021.102803.
    10.1016/j.jddst.2021.102803
  2. Cruz, Kercia P.; Patricio, Beatriz F. C.; Pires, Vinícius C.; Amorim, Marina F.; Pinho, Alan G. S. F.; Quadros, Helenita C.; Dantas, Diana A. S.; et al. "Development and Characterization of PLGA Nanoparticles Containing 17-DMAG, an Hsp90 Inhibitor". Frontiers in Chemistry 9 (2021): http://dx.doi.org/10.3389/fchem.2021.644827.
    10.3389/fchem.2021.644827
  3. Formiga, Fabio Rocha; Senel, Sevda. "Nanotechnology and Veterinary Drug/Vaccine Delivery". Pharmaceutical Nanotechnology 9 1 (2021): 4-4. http://dx.doi.org/10.2174/221173850901210312165458.
    10.2174/221173850901210312165458
  4. Fabio Rocha Formiga; Roger Leblanc; Juliana de Souza Rebouças; Leonardo Paiva Farias; Ronaldo Nascimento de Oliveira; Lindomar Pena. "Ivermectin: an award-winning drug with expected antiviral activity against COVID-19". Journal of Controlled Release (2021): https://doi.org/10.1016/j.jconrel.2020.10.009.
    10.1016/j.jconrel.2020.10.009
  5. "Emerging trends in nano- and microencapsulation science: hallmarks of the 22nd International Symposium on Microencapsulation". Drug Delivery and Translational Research 10 6 (2020): 1535-1536. http://dx.doi.org/10.1007/s13346-020-00865-7.
    10.1007/s13346-020-00865-7
  6. Jéssica Rebouças-Silva; Maraine Catarina Tadini; Danielle Devequi-Nunes; Ana Luíza Mansur; Paulo S Silveira-Mattos; Camila I de Oliveira; Fábio R Formiga; et al. "

    Evaluation of in vitro and in vivo Efficacy of a Novel Amphotericin B-Loaded Nanostructured Lipid Carrier in the Treatment of Leishmania braziliensis Infection

    ". International Journal of Nanomedicine (2020): https://doi.org/10.2147/IJN.S262642.
    10.2147/IJN.S262642
  7. Formiga, F.R.. "Nano-emulsification of Aeollanthus suaveolens Mart. Ex Spreng essential oil modifies its neuroeffects?". Drug Delivery and Translational Research (2020): http://dx.doi.org/10.1007/s13346-020-00846-w.
    10.1007/s13346-020-00846-w
  8. Formiga, F.R.. "Solid lipid nanoparticles as a novel formulation approach for tanespimycin (17-AAG) against Leishmania infections: preparation, characterization and macrophage uptake". Acta Tropica (2020): http://dx.doi.org/10.1016/j.actatropica.2020.105595.
    10.1016/j.actatropica.2020.105595
  9. FORMIGA, FABIO. "Levan-based nanostructured systems: An overview". International Journal of Pharmaceutics (2020): http://dx.doi.org/10.1016/j.ijpharm.2020.119242.
    10.1016/j.ijpharm.2020.119242
  10. Karoll Moangella Andrade De Assis; Renaly Ivyna de Araújo Rêgo; Demis Ferreira de Melo; Laryssa Mirelle da Silva; João Augusto Oshiro-Jr; Fábio Rocha Formiga; Vinícius Couto Pires; et al. "Therapeutic potential of Melaleuca alternifolia essential oil in new drug delivery systems". Current Pharmaceutical Design 26 (2020): https://doi.org/10.2174/1381612826666200305124041.
    10.2174/1381612826666200305124041
  11. FORMIGA, FABIO. "Development and in vitro characterization of polymeric nanoparticles containing recombinant adrenomedullin-2 intended for therapeutic angiogenesis". International Journal of Pharmaceutics (2020): http://dx.doi.org/10.1016/j.ijpharm.2019.118997.
    10.1016/j.ijpharm.2019.118997
  12. FORMIGA, FABIO. "The Novel Serine/Threonine Protein Kinase LmjF.22.0810 from Leishmania major may be Involved in the Resistance to Drugs such as Paromomycin". Biomolecules (2019): http://dx.doi.org/10.3390/biom9110723.
    10.3390/biom9110723
  13. FORMIGA, FABIO. "Encapsulation of the HSP-90 Chaperone Inhibitor 17-AAG in Stable Liposome Allow Increasing the Therapeutic Index as Assessed, in vitro, on Leishmania (L) amazonensis Amastigotes-Hosted in Mouse CBA Macrophages". Frontiers in Cellular and Infection Microbiology (2018): http://dx.doi.org/10.3389/fcimb.2018.00303.
    10.3389/fcimb.2018.00303
  14. FORMIGA, FABIO. "2017 TERMIS - Americas Conference & Exhibition Charlotte, NC December 3–6, 2017". Tissue Engineering Part A (2017): http://dx.doi.org/10.1089/ten.tea.2017.29003.abstracts.
    10.1089/ten.tea.2017.29003.abstracts
  15. Rebouças, J.S.; Santos-Magalhães, N.S.; Formiga, F.R.. "Cardiac regeneration using growth factors: Advances and challenges". Arquivos Brasileiros de Cardiologia 107 3 (2016): 271-275. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991336243&partnerID=MN8TOARS.
    10.5935/abc.20160097
  16. Formiga, F.R.; Pelacho, B.; Garbayo, E.; Imbuluzqueta, I.; Díaz-Herráez, P.; Abizanda, G.; Gavira, J.J.; et al. "Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration". Journal of Controlled Release 173 1 (2014): 132-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888106647&partnerID=MN8TOARS.
    10.1016/j.jconrel.2013.10.034
  17. Díaz-Herráez, P.; Garbayo, E.; Simón-Yarza, T.; Formiga, F.R.; Prosper, F.; Blanco-Prieto, M.J.. "Adipose-derived stem cells combined with Neuregulin-1 delivery systems for heart tissue engineering". European Journal of Pharmaceutics and Biopharmaceutics 85 1 (2013): 143-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882999655&partnerID=MN8TOARS.
    10.1016/j.ejpb.2013.03.022
  18. Simon-Yarza, T.; Tamayo, E.; Benavides, C.; Lana, H.; Formiga, F.R.; Grama, C.N.; Ortiz-de-Solorzano, C.; et al. "Functional benefits of PLGA particulates carrying VEGF and CoQ10 in an animal of myocardial ischemia". International Journal of Pharmaceutics 454 2 (2013): 784-790. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884151469&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2013.04.015
  19. Formiga, F.R.; Garbayo, E.; Díaz-Herráez, P.; Abizanda, G.; Simón-Yarza, T.; Tamayo, E.; Prósper, F.; Blanco-Prieto, M.J.. "Biodegradation and heart retention of polymeric microparticles in a rat model of myocardial ischemia". European Journal of Pharmaceutics and Biopharmaceutics 85 3 PART A (2013): 665-672. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888368659&partnerID=MN8TOARS.
    10.1016/j.ejpb.2013.02.017
  20. Simón-Yarza, T.; Formiga, F.R.; Tamayo, E.; Pelacho, B.; Prosper, F.; Blanco-Prieto, M.J.. "PEGylated-PLGA microparticles containing VEGF for long term drug delivery". International Journal of Pharmaceutics 440 1 (2013): 13-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871622076&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2012.07.006
  21. Formiga, F.R.; Tamayo, E.; Simón-Yarza, T.; Pelacho, B.; Prósper, F.; Blanco-Prieto, M.J.. "Angiogenic therapy for cardiac repair based on protein delivery systems". Heart Failure Reviews 17 3 (2012): 449-473. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862539591&partnerID=MN8TOARS.
    10.1007/s10741-011-9285-8
  22. Simón-Yarza, T.; Formiga, F.R.; Tamayo, E.; Pelacho, B.; Prosper, F.; Blanco-Prieto, M.J.. "Vascular endothelial growth factor-delivery systems for cardiac repair: An overview". Theranostics 2 6 (2012): 541-552. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864413702&partnerID=MN8TOARS.
    10.7150/thno.3682
  23. Formiga, F.R.; Pelacho, B.; Garbayo, E.; Abizanda, G.; Gavira, J.J.; Simon-Yarza, T.; Mazo, M.; et al. "Sustained release of VEGF through PLGA microparticles improves vasculogenesis and tissue remodeling in an acute myocardial ischemia-reperfusion model". Journal of Controlled Release 147 1 (2010): 30-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955824571&partnerID=MN8TOARS.
    10.1016/j.jconrel.2010.07.097
  24. FORMIGA, FABIO. "Spanish Society of Gene and Cell Therapy 2009 Oral Presentations". Human Gene Therapy (2009): http://dx.doi.org/10.1089/hum.2009.1721.
    10.1089/hum.2009.1721
  25. Formiga, F.R.; Fonseca, I.A.A.; Souza, K.B.; Silva, A.K.A.; Macedo, J.P.F.; Araújo, I.B.; Soares, L.A.L.; Egito, E.S.T.. "Influence of a lipophilic drug on the stability of emulsions: An important approach on the development of lipidic carriers". International Journal of Pharmaceutics 344 1-2 (2007): 158-160. http://www.scopus.com/inward/record.url?eid=2-s2.0-34648837038&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2007.05.052
  26. Macedo, J.P.F.; Fernandes, L.L.; Formiga, F.R.; Reis, M.F.; Nagashima Jr., T.; Soares, L.A.L.; Egito, E.S.T.. "Micro-emultocrit technique: A valuable tool for determination of critical HLB value of emulsions". AAPS PharmSciTech 7 1 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33645028206&partnerID=MN8TOARS.
    10.1208/pt070121
  27. Macedo, J.P.; Fernandes, L.L.; Formiga, F.R.; Reis, M.F.; Júnior, T.N.; Soares, L.A.; Egito, E.S.. "Micro-emultocrit technique: a valuable tool for determination of critical HLB value of emulsions.". AAPS PharmSciTech [electronic resource]. 7 1 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33645749359&partnerID=MN8TOARS.
  28. Do Egito, E.S.T.; Formiga, F.R.; Maurício, C.R.F.; Barbosa, R.J.F.; Prata, R.P.. "Tecnologia de fabricação de protectores solares empregando a emulsificação espontânea". Revista Portuguesa de Farmacia 51 4 (2001): 149-156. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042815016&partnerID=MN8TOARS.
Distinctions

Award

2017 Prêmio Benjamin Gilbert - Categoria Desenvolvimento Farmacêutico
Fundação Oswaldo Cruz, Brazil
2016 Vevo Award competition - Cardiovascular track
FUJIFILM VisualSonics, Inc.., Canada
2013 IV Edición del Premio de Investigación
Sociedad Española de Farmacia Industrial y Galénica (SEFIG), Spain

Other distinction

2019 Chair of the 22nd International Symposium on Microencapsulation
International Microencapsulation Society, Netherlands
2019 Vice-President - Brazilian Chapter of Controlled Release Society (CRS)
Controlled Release Society, United States
2019 Associate Editor - Drug Delivery and Translational Research (Springer)
Drug Delivery and Translational Research , United States