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Marília Mateus is an assistant professor at the Department of Bioengineering of Instituto Superior Técnico and senior researcher of iBB - Institute for Bioengineering and Biosciences, Universidade de Lisboa. She graduated in chemical engineering in 1984, got a master's degree in biotechnology (biochemical engineering) in 1988, and a doctoral degree in chemical engineering in 1994. Currently at academia, she coordinates the curricular units of "biological reactors" and "food technology". Her field of expertise is biomolecular and bioprocesses engineering with emphasis on bioreactors, purification of cell culture products and encapsulation of bioactives. One of her research focuses is the application of synthetic membranes to bioengineering fields; others , deal with the production of proteins (food and feed, immunogenic peptides) and nucleic acid vaccines. Recent projects encompass biorefinery and fermentation of marine resources (seaweeds and industrial fish discards). She has published 3 book chapters and 32 scientific articles in peer reviewed journals, supervised 3 doctoral and over 70 master theses, coordinated 3 national research projects and participated in other 5 (FCT funded), participates in one ongoing European project and coordinated another (at national level).
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Identification

Personal identification

Full name
Marília Clemente Velez Mateus

Author identifiers

Ciência ID
C713-2A86-7E83
ORCID iD
0000-0002-2235-3988
Scopus Author Id
6603684675

Email addresses

  • marilia.mateus@tecnico.ulisboa.pt (Professional)

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology - Bioprocessing Technologies
  • Engineering and Technology - Other Engineering and Technologies - Food and Beverages
  • Engineering and Technology - Nano-technology
Education
Degree Classification
1994/07
Concluded
 Engenharia Química (Doutoramento)
Major in Outra:Processos de Separação
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
"Recuperação de Esteróides de Meios de Biotransformação por Processos de Membranas" (THESIS/DISSERTATION)
 Distinção e Louvor
1988/10
Concluded
 Biotecnologia (Mestrado)
Major in Engenharia Bioquímica
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
"Separação de Células de Arthrobacter simplex com Actividade de Desidrogenase delta-1,2 por Processos de Membranas" (THESIS/DISSERTATION)
 Muito Bom
1984/09
Concluded
 Engenharia Química (Licenciatura)
Major in Tecnologia e Indústria
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 15 (quinze) valores
Affiliation

Science

Category
Host institution 		Employer
1988 - 1990/01/02 Research Trainee (Research) Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
Instituto Superior Técnico, Departamento de Engenharia Química, Portugal
1985 - 1987 Research Trainee (Research) Junta Nacional de Investigação Científica e Tecnológica, Portugal
Laboratório Nacional de Engenharia e Tecnologia Industrial, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2013 - Current Assistant Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal
Instituto Superior Técnico, Departamento de Bioengenharia, Portugal
2015/02/01 - 2015/07/31 Visiting Professor (University Teacher) University College London - Advanced Centre for Biochemical Engineering, United Kingdom
University College London - Advanced Centre for Biochemical Engineering, United Kingdom
(...)
2011 - 2013 Assistant Professor (University Teacher) Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
Instituto Superior Técnico, Departamento de Bioengenharia, Portugal
1994/07 - 2010 Assistant Professor (University Teacher) Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
Instituto Superior Técnico, Departamento de Engenharia Biológica e Química, Portugal
1990/01/03 - 1994/07 Assistant (University Teacher) Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
Instituto Superior Técnico, Departamento de Engenharia Química, Portugal

Others

Category
Host institution 		Employer
1987 - 1988/10 Bolseira de Mestrado Junta Nacional de Investigação Científica e Tecnológica, Portugal
Instituto Superior Técnico, Departamento de Engenharia Química, Portugal
Projects

Contract

Designation Funders
2023/09 - 2027/08 Alternative PROteins from MIcrobial fermentation of non-conventional SEA sources for Next-Generation food, feed and non-food bio-based applications
101112378
Co-Principal Investigator (Co-PI)
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
European Commission
Ongoing
2019 - 2021 Smart Valorisation of Macroalgae
FA_05_2017_033
Researcher
Instituto Superior Técnico, Departamento de Bioengenharia, Portugal
 Ministério do Mar
Concluded
2016/04/01 - 2019/06/30 PureMAb - Multimodal chromatography as an alternative to pure chromatographic modes for the capture and polishing of antibody streams.
PTDC/QEQ-PRS/0286/2014
Researcher
Fundação para a Ciência e a Tecnologia
2012/01/01 - 2014/12/31 DSPMab - Intensification of the Downstream Process of Monoclonal Antibodies.
PTDC/EQU-EPR/117427/2010
Researcher
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Improvement of the immunogenicity of DNA vaccines
PTDC/EBB-EBI/113650/2009
Researcher
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/02/01 - 2013/01/31 Membrane Chromatographic Matrices for Plasmid-DNA Purification: rational design based on biochemical and biophysical interactions.
PTDC/EBB-EBI/100925/2008
Principal investigator
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009/09/01 - 2012/08/31 LIRACORK - "Harmless Binders for Agglomerated Cork Stoppers"
5012/2008 (ADI-Agência de Inovação)
Researcher
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
Concluded
2007/10/01 - 2010/09/30 Synthesis, Optimization and Intensification of Bioseparation Processes for DNA Vaccine Manufacturing.
PTDC/EQU-EQU/65492/2006
Researcher
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal

Universidade da Beira Interior, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2000/10/01 - 2002/09/30 Bio-Artificial Pancreas: preliminary studies of hemocompatibility, diffusion and immunoisolation.
POCTI/BIO/12007/2000
Principal investigator
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
1996/01/02 - 1998/12/31 Fundamental Studies of Microfiltration for the Fractionation of Colloidal Mixtures: experimental validation with the recovery of a recombinant enzyme.
BICT/P/BIO/1985/95
Principal investigator
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia

Other

Designation Funders
1995/12/01 - 1997/08/31 FIDEL – Food Internet-based Distance European Learning.
TM–OP–1995–1–SE–18
Principal investigator
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
 European Commission
Concluded
Outputs

Publications

Book chapter
  1. Silva, A.I.; de Matos, A.N.; Brons, I.G.M.; Mateus, M.C.V.. "Membranes in Bioartificial Pancreas - An Overview of the Development of a Bioartificial Pancreas, as a Treatment of Insulin-Dependent Diabetes Mellitus". 2010.
    Published • 10.1002/9783527631360.ch9
  2. M. Mateus, J.A.L. Santos and J.M.S. Cabral. "Membrane separation processes". In Recovery Processes for Biological Materials, 177-222. Chichester, United Kingdom: John Wiley & Sons, 1993.
    Published
  3. J.A.L. Santos, M. Mateus and J.M.S. Cabral. "Pressure Driven Membrane Processes". In Chromatographic and Membrane Processes in Biotechnology, edited by C.A. Costa and J.M.S. Cabral. Springer Netherlands, 1991.
Conference abstract
  1. Guerra, I.; Costa, M.; Silva, J.T.; Pereira, H.; Varela, J.; M. Mateus; Silva, J.. Corresponding author: Costa, M.. "Nannochloropsis oceanica cultivation under different culture systems: productivity and nutritional comparison". Paper presented in AlgaEurope 2020, Rome, 2020.
    Published
Conference paper
  1. Mateus, M.; Raiado-Pereira, L.; Prazeres, D.M.F.. "Toward therapeutic plasmids purification by hydrophobic interaction membrane chromatography". 2012.
    10.1016/j.proeng.2012.08.630
  2. Monteiro, M.E.; Raiado-Pereira, L.; Prazeres, D.M.F.; Mateus, M.. "Liposome derived membrane adsorber for purification of nucleic acids". 2012.
    10.1016/j.proeng.2012.08.829
  3. Mateus, M.; Raiado-Pereira, L.; Prazeres, M.. "Membrane chromatography for therapeutic DNA production: Adsorption membranes development". 2011.
    10.1109/ENBENG.2011.6026054
Conference poster
  1. Diogo Marques; Marta Brandão; Mateus, Marília; Helena Pinheiro; M. Teresa Cesário. Corresponding author: M. Teresa Cesário. "ULva sp. and industrial residues of the red seaweed Gelidium corneum as platforms for producing alternative proteins through microbial fermentation". Paper presented in Seagriculture EU 2024 | 13th International Seaweed Conference EU, 2024.
  2. Gonçalo Espírito Santo et al.. "Unlocking the Potential of Heterotrophic Microalgae-derived Functional Ingredients for Aquafeed Solutions". Paper presented in AlgaEurope 2023, 2023.
  3. Shirley, R ; Leandro, T.; Abreu, B.; Machado, R ; M. Mateus; Pinheiro, H. M.; da Fonseca, MMR; Instituto Superior Técnico - M. Teresa Cesário Smolders (PI). Corresponding author: Instituto Superior Técnico - M. Teresa Cesário Smolders (PI). "Valorization of Ulva lactuca – production of protein-rich ingredients for aquafeed and of sugar-hydrolysates for bioplastic production from different fractions of this macroalgae". Paper presented in RRB 2021 - 17th International Conference on Renewable Resources & Biorefineries, Aveiro, Portugal, 6-8 Setembro 2021., 2021.
  4. Guerra, Inês ; Silva, Joana T. ; Costa, Margarida ; Pereira, Hugo ; Varela, João ; Mateus, Marília; Silva, Joana . Corresponding author: Costa, Margarida. "Culture systems: a comparison based on Nannochloropsis oceanica productivity and nutritional value". Paper presented in MICROBIOTEC'19, 2019.
Journal article
  1. Mafalda Trovão; Lucas Cardoso; Lisa Schüler; Adriana Machado; Gonçalo Espírito Santo; Humberto Pedroso; Ana Reis; et al. "Oxyfluorfen: a novel metabolic inhibitor to select microalgal chlorophyll-deficient mutant strains for nutritional applications". Algal Research (2024): http://dx.doi.org/10.1016/j.algal.2024.103572.
    10.1016/j.algal.2024.103572
  2. Marília Mateus; Rita Mão de Ferro; Helena M. Pinheiro; Remígio Machado; M. Manuela R. da Fonseca; Maria Sapatinha; Carla Pires; et al. "Production and characterization of protein-rich extracts from the red macroalga Gelidium corneum and its industrial agar extraction residues". Algal Research (2024): http://dx.doi.org/10.1016/j.algal.2024.103420.
    Published • 10.1016/j.algal.2024.103420
  3. Gonçalo Espírito Santo; Ana Barros; Margarida Costa; Hugo Pereira; Mafalda Trovão dos Santos; Helena Cardoso; Bernardo Carvalho; et al. "Scenedesmus rubescens Heterotrophic Production Strategies for Added Value Biomass". Marine Drugs 21 7 (2023): 411. https://www.mdpi.com/1660-3397/21/7/411.
    Open access • Published • 10.3390/md21070411
  4. Vanessa A. Botelho; Marília Mateus; José C. C. Petrus; Maria Norberta de Pinho. "Membrane Bioreactor for Simultaneous Synthesis and Fractionation of Oligosaccharides". Membranes 12 2 (2022): 171-171. https://doi.org/10.3390/membranes12020171.
    10.3390/membranes12020171
  5. Mariana Gordalina; Helena M. Pinheiro; Marília Mateus; M. Manuela R. da Fonseca; M. Teresa Cesário. "Macroalgae as Protein Sources - A Review on Protein Bioactivity, Extraction, Purification and Characterization". Applied Sciences 11 17 (2021): 7969-7969. https://doi.org/10.3390/app11177969.
    10.3390/app11177969
  6. Inês Guerra; Hugo Pereira; Margarida Costa; Joana T. Silva; Tamára Santos; João Varela; Marília Mateus; Joana Silva. "Operation Regimes: A Comparison Based on Nannochloropsis oceanica Biomass and Lipid Productivity". Energies 14 6 (2021): 1542-1542. https://doi.org/10.3390/en14061542.
    10.3390/en14061542
  7. Wagner, A.; Ferraria, A.M.; Do Rego, A.M.B.; Mateus, M.; Azevedo, A.M.. "Purification of monoclonal antibodies in a stirred cell with polyethyleneimine-modified polyethersulfone ultrafiltration membrane". Journal of Chemical Technology and Biotechnology 94 11 (2019): 3548-3558. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070713091&partnerID=MN8TOARS.
    10.1002/jctb.6157
  8. Completo, C.; Geraldes, V.; Semião, V.; Mateus, M.; Rodrigues, M.. "Comparison between microfluidic tangential flow nanofiltration and centrifugal nanofiltration for the concentration of small-volume samples". Journal of Membrane Science 578 (2019): 27-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061553929&partnerID=MN8TOARS.
    10.1016/j.memsci.2019.02.022
  9. António L. Grilo; Marília Mateus; Maria R. Aires-Barros; Ana M. Azevedo. "Monoclonal Antibodies Production Platforms: An Opportunity Study of a Non-Protein-A Chromatographic Platform Based on Process Economics". Biotechnology Journal (2017): 1700260-1700260. https://doi.org/10.1002/biot.201700260.
    10.1002/biot.201700260
  10. Rauta, P.R.; Nayak, B.; Monteiro, G.A.; Mateus, M.. "Design and characterization of plasmids encoding antigenic peptides of Aha1 from Aeromonas hydrophila as prospective fish vaccines". Journal of Biotechnology 241 (2017): 116-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-85000501233&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2016.11.019
  11. Completo, C.; Geraldes, V.; Semião, V.; Mateus, M.; Rodrigues, M.. "Centrifugal nanofiltration for small-volume samples". Journal of Membrane Science 540 (2017): 411-421. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021688044&partnerID=MN8TOARS.
    10.1016/j.memsci.2017.06.069
  12. Saldanha Do Carmo, C.; Pais, R.; Simplício, A.L.; Mateus, M.; Duarte, C.M.M.. "Improvement of Aroma and Shelf-Life of Non-alcoholic Beverages Through Cyclodextrins-Limonene Inclusion Complexes". Food and Bioprocess Technology (2017): 1-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016089706&partnerID=MN8TOARS.
    10.1007/s11947-017-1897-0
  13. Monteiro, M. E.; Raiado-Pereira, L.; Prazeres, D. M. F.; Mateus, M.. "Preparation of liposome membrane adsorbers and testing for plasmid purification". Biochemical Engineering Journal 93 (2015): 1-10. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000347362100001&KeyUID=WOS:000347362100001.
    10.1016/j.bej.2014.09.005
  14. Nascimento, A.; Rosa, S.A.S.L.; Mateus, M.; Azevedo, A.M.. "Polishing of monoclonal antibodies streams through convective flow devices". Separation and Purification Technology 132 (2014): 593-600. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903717887&partnerID=MN8TOARS.
    10.1016/j.seppur.2014.06.005
  15. Raiado-Pereira, L.; Vega, J.D.L.; Prazeres, D.M.F.; Mateus, M.. "Development of a phenyl membrane chromatography-based process yielding pharmaceutical grade plasmid deoxyribonucleic acid for mammalian cells transfection". Journal of Chromatography A 1337 (2014): 67-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900661426&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.02.024
  16. Raiado-Pereira, L.; Prazeres, D.M.F.; Mateus, M.. "Impact of plasmid size on the purification of model plasmid DNA vaccines by phenyl membrane adsorbers". Journal of Chromatography A 1315 (2013): 145-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885371617&partnerID=MN8TOARS.
    10.1016/j.chroma.2013.09.076
  17. Raiado-Pereira, L.; Carapeto, A.P.; Botelho Do Rego, A.M.; Mateus, M.. "Grafting hydrophobic and affinity interaction ligands on membrane adsorbers: A close-up "view" by X-ray photoelectron spectroscopy". Separation and Purification Technology 93 (2012): 75-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859936134&partnerID=MN8TOARS.
    10.1016/j.seppur.2012.03.028
  18. Pereira, L.R.; Prazeres, D.M.F.; Mateus, M.. "Hydrophobic interaction membrane chromatography for plasmid DNA purification: Design and optimization". Journal of Separation Science 33 9 (2010): 1175-1184. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952206845&partnerID=MN8TOARS.
    10.1002/jssc.200900844
  19. Botelho-Cunha, V.A.; Mateus, M.; Petrus, J.C.C.; de Pinho, M.N.. "Tailoring the enzymatic synthesis and nanofiltration fractionation of galacto-oligosaccharides". Biochemical Engineering Journal 50 1-2 (2010): 29-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-82055192911&partnerID=MN8TOARS.
    10.1016/j.bej.2010.03.001
  20. Silva, A.I.; Mateus, M.. "Development of a polysulfone hollow fiber vascular bio-artificial pancreas device for in vitro studies". Journal of Biotechnology 139 3 (2009): 236-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-58849159158&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2008.12.004
  21. Catarino, I.; Minhalma, M.; Beal, L.L.; Mateus, M.; de Pinho, M.N.. "Assessment of saccharide fractionation by ultrafiltration and nanofiltration". Journal of Membrane Science 312 1-2 (2008): 34-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-39749096567&partnerID=MN8TOARS.
    10.1016/j.memsci.2007.12.057
  22. Silva, A.I.; Norton De Matos, A.; Brons, I.G.; Mateus, M.. "An overview on the development of a bio-artificial pancreas as a treatment of insulin-dependent diabetes mellitus". Medicinal Research Reviews 26 2 (2006): 181-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644669226&partnerID=MN8TOARS.
    10.1002/med.20047
  23. Minhalma, M.; Beal, L.L.; Catarino, I.; Mateus, M.; de Pinho, M.N.. "Optimization of saccharide fractionation using nanofiltration/ultrafiltration". Desalination 199 1-3 (2006): 337-339. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746680381&partnerID=MN8TOARS.
    10.1016/j.desal.2006.03.079
  24. Vojinovic, V.; Calado, C.R.; Silva, A.I.; Mateus, M.; Cabral, J.M.S.; Fonseca, L.P.. "Micro-analytical GO/HRP bioreactor for glucose determination and bioprocess monitoring". Biosensors and Bioelectronics 20 10 SPEC. I (2005): 1955-1961. http://www.scopus.com/inward/record.url?eid=2-s2.0-14644389383&partnerID=MN8TOARS.
    10.1016/j.bios.2004.08.015
  25. Leirião, P.R.S.; Fonseca, L.J.P.; Taipa, M.A.; Cabral, J.M.S.; Mateus, M.. "Horseradish peroxidase immobilized through its carboxylic groups onto a polyacrylonitrile membrane: Comparison of enzyme performances with inorganic beaded supports". Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology 110 1 (2003): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042166222&partnerID=MN8TOARS.
    10.1385/ABAB:110:1:1
  26. Sousa, A.C.C.; Mateus, M.. "Application of factorial design to microfiltration performance: Study of electrostatic and hydrodynamic effects". Chemical Engineering Research and Design 81 2 (2003): 271-276. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037311974&partnerID=MN8TOARS.
    10.1205/026387603762878746
  27. Cláudia Sousa, A.; Cabral, J.M.S.; Mateus, M.. "Microfiltration of cutinase and Escherichia coli cell fragment suspensions. The role of the electrolyte environment on the development of dynamic cake layers". Journal of Membrane Science 207 2 (2002): 171-187. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037105921&partnerID=MN8TOARS.
    10.1016/S0376-7388(02)00173-4
  28. Ferreira, B.S.; Fernandes, H.L.; Reis, A.; Mateus, M.. "Microporous hollow fibres for carbon dioxide absorption: Mass transfer model fitting and the supplying of carbon dioxide to microalgal cultures". Journal of Chemical Technology and Biotechnology 71 1 (1998): 61-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031973715&partnerID=MN8TOARS.
    10.1002/(SICI)1097-4660(199801)71:1<61::AID-JCTB785>3.0.CO;2-R
  29. Mateus, M.; Cabral, J.M.S.. "Modeling membrane filtration of protein and cell suspensions in a vortex flow filtration system". AIChE Journal 41 4 (1995): 764-772. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029278483&partnerID=MN8TOARS.
    10.1002/aic.690410403
  30. Mateus, M.; Cabral, J.M.S.. "Steroid recovery by a rotary membrane system". Biotechnology Techniques 5 1 (1991): 43-48. http://www.scopus.com/inward/record.url?eid=2-s2.0-0006371903&partnerID=MN8TOARS.
    10.1007/BF00152754
  31. Mateus, M.; Cabral, J.M.S.. "Recovery of 6-a-methylprednisolone from biotransformation medium by tangential flow filtration". Bioprocess Engineering 4 4 (1989): 169-174. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024493513&partnerID=MN8TOARS.
    10.1007/BF00369396
  32. Anselmo, A.M.; Mateus, M.; Cabral, J.M.S.; Novais, J.M.. "Degradation of phenol by immobilized cells of Fusarium flocciferum". Biotechnology Letters 7 12 (1985): 889-894. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022400069&partnerID=MN8TOARS.
    10.1007/BF01088011
Journal issue
  1. Mateus, Marília. "Bioprocessing with Membranes: Filtration and Chromatography". Membranes (2022): https://www.mdpi.com/journal/membranes/special_issues/membranes_filtration_chromatography.
    In press • Invited editor
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/12/12 Fermentation strategies using food grade microbes for nutritional and economic valorisation of Ulva rigida biomass AlgaEurope 2024
EABA - European Algae Biomass Association; DLG Benelux. (Atenas / Athens, Greece)
2022/06/02 Production of protein-rich powders from the red macroalga Gelidium sesquipedale and from its industrial residues 18th International Conference on Renewble Resources and Biorefinaries
(Bruges, Belgium)
2022/06/02 Biorefinery of the green seaweed Ulva lactuca: protein fraction for aquafeed and carbohydrates for microbial polyesters production 18th International Conference on Renewble Resources and Biorefinaries
(Bruges, Belgium)
2020/12/11 Development of pH-sensitive membranes with enhanced antifouling performance for the valorisation of side streams in the pulp industry ICOM 2020 - 12th International Congress on Membranes & Membrane Processes
European Membrane Society (Online, United Kingdom)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/02/01 - 2024/12/06 Towards the Valorization of Fish Skin Discards. Studies on enzyme hydrolysis and on protein extraction by a deep eutectic solvent
Supervisor
 Engenharia Química (Master)
Instituto Superior Técnico, Departamento de Engenharia Química, Portugal
2024/02/01 - 2024/11/26 Deep Eutectic Solvents application towards the valorization of Geldium corneum and Ulva rigida industrial residues
Supervisor
 Engenharia Biológica (Master)
Instituto Superior Técnico, Departamento de Bioengenharia, Portugal
2024/02/01 - 2024/09/30 Development of nanoparticles for efficient mucosal co-delivery of protein antigens of H. pylori and immunoadjuvants
Co-supervisor of Inês Moreira Guerreiro
Instituto Superior Técnico, Departamento de Bioengenharia, Portugal
2023/09/15 - 2024/04/15 Development and implementation of a serum agglutination test for evaluating the efficacy of autogenous vaccines. Case study of formulation and development of a Mycoplasma bovis vaccine
Supervisor of Simão Faria de Almeida Casaleiro
 Engenharia Biológica (Master)
Instituto Superior Técnico, Departamento de Bioengenharia, Portugal
2022/10 - 2023/07/10 Lactic acid and yeast fermentation of Ulva rigida in bench-scale bioreactors to improve protein content and nutritional value
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - 2022/12/10 Exhaustive characterization of microalgal heterotrophic cultivation - A case study of Chlorella vulgaris throughout industrial scale up
Supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/02 - 2022/09 Development of novel Scenedesmus rubescens mutants with improved pigmentation and protein contents
Co-supervisor
 Biotecnologia (Master)
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
2021/02/01 - 2021/12/10 Fermentation of Porphyra umbilicalis hydrolysate by lactic acid bacteria and Saccharomyces cerevisiae to improve protein content and nutritional value
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - 2021/11/29 OmpK antigenic peptide from Vibrio alginolyticus in recombinant Escherichia coli - production and secretion challenges
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - 2021/11/22 Production and characterization of protein rich extracts from the red macroalga Gelidium sesquipedale and its residues after industrial agar extraction
Supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - 2021/11/22 Lactic acid fermentation of industrial residues from the macroalga Gelidium corneum towards the improvement of protein content and nutritional value
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/09/07 - 2021/10/11 Desenvolvimento e avaliação de vacinas de DNA contra Photobacterium damselae subsp. piscicida
Supervisor
 Biotecnologia dos Recursos Marinhos (Master)
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2020/03 - 2020/12 A simulação computacional como ferramenta de apoio ao controlo do processo fermentativo numa cervejeira artesanal
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/03 - 2020/12 Scenedesmus rubescens production strategies for added value biomass
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/02 - 2020/12 Aggregation behaviour of plant proteins
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/02 - 2020/12 Extraction of the protein fraction from selected protein-rich seaweeds
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/02 - 2020/10/08 Development of an oral pDNA vaccine against Vibrio species
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09 - 2020/07/17 Novel Polymeric Ultrafiltration Membranes – Performance, Retention, Fouling and Cleaning Analysis
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Development of a piezoelectric immunosensor for antibody titration for vaccinated fish
Supervisor of Ricardo Vieira Ribeiro
 Bioengenharia e Nanossistemas (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Synthesis and characterization of nanoparticles as DNA vaccine carriers for fish immunization
Supervisor of Martim de Sousa Gil Cardeira
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2017 Studies with Vibrio alginolyticus OmpK towards the development of a vaccine for aquacultured Solea senegalensis
Supervisor of João Bruno Fiuza Almeida Lopes
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2017 Extraction and characterization of microalgae protein from the extremophile Dunaliella
Supervisor of Diana Isabel Costa Gomes
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2017 Production, purification and refolding of recombinant Omp K for ELISA assays: testing DNA vaccination against Vibrio alginolyticus in Solea senegalensis fish
Supervisor of Mariana Sousa Jerónimo
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Stirred cell purification of monoclonal antibodies by ultrafiltration with polyethyleneimine-modified polyethersulfone membrane
Supervisor of Alexandra Isabel Ribeiro Wagner
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Produção de proteínas membranares de Vibrio alginolyticus para vacinação
Supervisor of Ayéwa Lawoé Agognon
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 - 2014/10/09 Hydrophobic Interaction Membrane Chromatography for the Downstream Processing of Plasmid DNA
Supervisor of Luís Miguel de Oliveira e Silva Raiado Pereira
 Biotecnologia (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Polishing of Monoclonal Antibodies Stream through Convective Flow Devices
Co-supervisor of André Nunes dos Santos Nascimento
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2003 - 2009 Study of a Membrane Bioreactor as a Model of Bio-artificial Pâncreas
Supervisor of Ana Isabel Quinta dos Santos Silva
 Engenharia Química (PhD)
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal
1999 - 2003 Influência de Parâmetros Electrocinéticos na Filtração de Suspensões Biológicas Contendo Cutinase Ou Plasmídeo Pcf1-cftr
Supervisor of Ana Cláudia Cavaco de Sousa
 Biotecnologia (PhD)
Instituto Superior Técnico, Universidade Técnica de Lisboa, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/11/16 - 2024/11/16 Comissão organizadora de conferência /Organizing committee of conference: MicroSummit 2024 ( https://microsummit-2024.com/ )
Conference
 MicroSummit 2024
Sociedade Portuguesa de Microbiologia, Portugal
2024/10/04 - 2024/10/05 Moderadora de mesa redonda / Moderator of roundtable: "Future of Food – Synergies between Cellular Agriculture and other emerging food sources", at the II International Conference of the Portuguese Association for Cellular Agriculture ( https://cellagri.pt/cellagri2024 )
Conference
 II International Conference of the Portuguese Association for Cellular Agriculture
Portuguese Association for Cellular Agriculture, Portugal
2021/09/06 - 2021/09/08 Moderadora de sessão científica na conferência internacional RRB 2021 / Chairperson in scientific session of the international conference RRB 2021
Conference
 17th International Conference on Renewable Resources & Biorefineries, Aveiro, Portugal, 6-8 Setembro 2021. https://rrbconference.com/programme-tuesday-7-september-2021/
Universiteit Gent, Belgium
2015/05/20 - 2015/05/22 Formação profissional / Professional development: “From Innovation to Commercialisation: How to Create a Sustainable Life-Cycle” – a 3-days VISION Core Course “Executive Training for the Bio Industries”; programme leadership by Prof. Eli Keshavarz-Moore, 20-22 May 2015 at UCL, London UK [Conducters: Steve Arlington, Pharmaceuticals Consultancy, PWC LLP; Michelle Scott, Biologics Director, Covance Laboratories; Barry Buckland, CEO, BiologicB; Alain Pralong, VP Product Introduction GSK Biologics; Rahul Singhvi, COO, Takeda Vaccines; and more]
Workshop
 From Innovation to Commercialisation: How to Create a Sustainable Life-Cycle
University College London - Advanced Centre for Biochemical Engineering, United Kingdom
2015/03/18 - 2015/03/18 Formação profissional / Professional development: “Downstream Processing for Biologics Manufacture: What are the R&D priorities for the next 25 years?” – a workshop for professionals coordinated by Dennis Sherwood from ‘The Silver Bullet Machine Manufacturing Company Limited’ for BioProNet, on 18 March 2015 at UCL, London UK.
Workshop
 Downstream Processing for Biologics Manufacture: What are the R&D priorities for the next 25 years?
University College London - Advanced Centre for Biochemical Engineering, United Kingdom