Identification
Personal identification
- Full name
- Mariana Pereira de Magalhães
Citation names
- Magalhães, M
Author identifiers
- Ciência ID
- C816-7709-6E8C
- ORCID iD
- 0000-0002-1874-1611
- Google Scholar ID
- https://scholar.google.com/citations?view_op=list_works&hl=pt-PT&user=UAa8TZAAAAAJ
- Researcher Id
- F-6429-2018
Websites
- https://www.researchgate.net/profile/Mariana_Magalhaes2 (Professional)
- https://www.linkedin.com/in/mariana-magalhães-72167a31 (Professional)
- https://loop.frontiersin.org/people/1702141/overview (Professional)
- https://doi.org/10.54499/SFRH/BD/146441/2019 (Scholar)
Knowledge fields
- Engineering and Technology - Nano-technology - Nano-materials
- Medical and Health Sciences - Medical Biotechnology - Biomaterials
- Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
- Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
- Natural sciences - Biological Sciences - Molecular Biology
- Natural sciences - Biological Sciences - Biochemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Spanish; Castilian | Beginner (A1) | Intermediate (B1) | Beginner (A1) | Intermediate (B1) | Intermediate (B1) |
Italian | Beginner (A1) | Elementary (A2) | Beginner (A1) | Elementary (A2) | Beginner (A1) |
Education
Degree | Classification | |
---|---|---|
2019/10/04 - 2024/03/04
Concluded
|
Experimental Biology and Biomedicine (Doutoramento)
Major in Biotechnology and Health
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
"Treating glioblastoma: a novel therapeutic approach based on natural products" (THESIS/DISSERTATION)
|
Approved with Praise and Distinction |
2021/03/18 - 2021/03/20
Concluded
|
Models of the Blood-Brain Barrier: Scientific Tools to Target the Brain (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
|
2020/02 - 2020/02
Concluded
|
Connecting researchers with society (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
18 |
2019/11 - 2019/11
Concluded
|
Functional Neuroanatomy (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra, Portugal
|
|
2019
Concluded
|
Proteomics Approaches in Life Sciences (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
|
2017/02/03
Concluded
|
Laboratory Animal Science (Diploma de especialização)
Major in Function B
Universidade de Trás-os-Montes e Alto Douro, Portugal
|
15 |
2014/03
Concluded
|
Certificate of Pedagogical Skills Trainer (CCP) (Diploma de especialização)
Instituto do Emprego e Formação Profissional, Portugal
|
Relevant |
2011 - 2013
Concluded
|
Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Development of a new lipid-based nanosystem for specific and efficient gene delivery into hepatocellular carcinoma cells" (THESIS/DISSERTATION)
|
16 |
2010
Concluded
|
Biological Engineering (Licenciatura)
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
"Orgânic and mineral analysis of a sample from Bairrada soil and its influence on the wine sector" (THESIS/DISSERTATION)
|
12 |
2009
Concluded
|
English course (Diploma de especialização)
International House World Organisation, Portugal
|
15 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2024/06/01 - Current | Science and Technology Management | Universidade de Coimbra, Portugal |
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal | ||
2020/01/01 - 2024/02/29 | Researcher (Research) | Fundação para a Ciência e a Tecnologia, Portugal |
Universidade de Coimbra Faculdade de Medicina, Portugal (...) |
||
2019/04/01 - 2019/12/31 | Researcher (Research) | Universidade de Coimbra Faculdade de Medicina, Portugal |
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal | ||
2016/06/01 - 2019/03/31 | Researcher (Research) | Universidade de Coimbra Faculdade de Farmácia, Portugal |
2014/10/13 - 2015/05/31 | Researcher (Research) | Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal |
2012/09/03 - 2013/12/31 | Research Trainee (Research) | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2024/06 - Current | Volunteer Postdoctoral Researcher | Universidade de Coimbra, Portugal |
2023/06/01 - 2023/07/31 | Researcher - Visiting PhD student | Fundação para a Ciência e a Tecnologia, Portugal |
Università degli Studi di Bologna, Italy |
Projects
Contract
Designation | Funders | |
---|---|---|
2024/06 - Current | EXCELScIOR: EXCELlent Science with Impact, Open and Reliable
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
|
European Commission
Ongoing
|
2020/01/01 - 2024/02/29 | Treating glioblastoma: a novel therapeutic approach based on natural products
SFRH/BD/146441/2019
PhD Student Fellow
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2018/07/26 - 2021/07/25 | Novel therapeutic strategy for osteosarcoma combining polyplexes and polymeric micelles
PTDC/BTM-MAT/30255/2017
Researcher
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2019/04/01 - 2019/12/31 | MEDPERSYST - Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan
SAICTPAC/0010/2015
Research Fellow
Universidade de Coimbra, Portugal
Universidade de Aveiro, Portugal Universidade do Minho, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2019/01/01 - 2019/12/31 | Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
UID/QUI/50006/2019
LA/P/0008/2020
Research Fellow
Universidade do Porto Faculdade de Ciências, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade Nova de Lisboa, Portugal Universidade de Aveiro, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade de Évora, Portugal Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal Universidade de Lisboa Instituto Dom Luiz, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2016/06/01 - 2019/03/31 | Development and characterization of smart micelleplexes for lung cancer therapy
PTDC/CTM-BIO/1518/2014
Research Fellow
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2014/10 - 2015/05 | Therapeutic drug monitoring on age related diseases - CENTRO-07-ST24-FEDER-002012
CENTRO-07-ST24-FEDER-002012
Research Fellow
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
|
Concluded
|
2011/01/01 - 2014/06/30 | Development of a novel therapeutic strategy for pancreatic cancer involving a concerted action of gene therapy and chemotherapeutic
agents
PTDC/SAU-BMA/114482/2009
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Conference paper |
|
Conference poster |
|
Journal article |
|
Preprint |
|
Thesis / Dissertation |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/01/29 | Nature’s weapon against glioblastoma: unraveling the 7a-acetoxy-6ß-hydroxyroyleanone (Roy) antitumor mechanism of action | IV Metabolism, Ageing & Disease (MAD) Meeting Disease & Therapeutics: from the Past to Future
(Coimbra, Portugal)
|
2023/12/01 | How does the natural compound 7a-acetoxy-6ß-hydroxyroyleanone (Roy) modulates glioblastoma cells autophagy? | Mitochondria in Aging, Cancer and Cell Death (MAC) 2023: A Gathering of Experts in Mitochondria Research
(Coimbra, Portugal)
|
2023/07/13 | Plectranthus ecklonii Benth.: a potential plant with clinical use? | III Bio.Natural 2023 – Bioactive Natural Products Research Meeting
(Lisbon, Portugal)
|
2023/07/02 | Plectranthus diterpenes: A promising therapy for glioblastoma treatment | 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
(Dublin, Ireland)
|
2022/09 | Essential oils from Côa Valley Lamiaceae species: cytotoxicity on glioblastoma cells | 52nd International Symposium on Essential Oils
(Wroclaw, Poland)
|
2021/11/18 | Chemoprevention and Therapeutic Role of Phytochemicals in Glioblastoma | II Bio.Natural 2021 – Bioactive Natural Products Research |
2019/07 | Antiproliferative and cytotoxic proprieties of Ridolfia segetum essential oils in in vitro cancer models | Natural Products in Drug Discovery and Human Health (NatProdDDH)
Phytochemical Society of Europe (Lisbon, Portugal)
|
2017/04 | Formulation and characterization of smart micellar complexes for lung cancer treatment | 1st SPLC-CRS Young Scientist Meeting
Spanish Portuguese Local Chapter- Controlled Realease Society (Santiago de Compostela, Spain)
|
2015/04 | Comparação de duas técnicas de extração para a quantificação de anticoagulantes e antiagregantes plaquetários em sangue por UHPLC-DAD | IV Encontro Nacional em Pós-graduação em Ciências Biológicas
(Aveiro, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2021/05/01 - 2021/07/31 | The antiproliferative and cytotoxic effect of Ridolfia Segetum (L.) Moris essential oil in A172 cell line
Co-supervisor of Francisco Daniel Amaral Henriques da Cruz Martins
|
Biotecnologia (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
|
2021/05/01 - 2021/07/31 | The antiproliferative and cytotoxic effect of Ridolfia segetum (L.) Moris essential oil in the U87-MG glioblastoma cell line.
Co-supervisor of Maria Fernandes Rosa
|
Biotecnologia (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2023 - 2023 | Member of the Organizer Committee of “PhDoing: Science Today, Innovation Tomorrow!”, a meeting organized by the PhD students
from the Coimbra Institute for Clinical and Biomedical Research (iCBR) (2023/05/26 - 2023/05/27)
Meeting (Member of the Organising Committee)
|
|
2022/02/26 - 2022/02/26 | Tutor of the workshop "Medicinal Plants: The other side of Drugs" at the XI In4Med event. (2022/02/26 - 2022/02/26)
Workshop (Other)
|
Universidade de Coimbra Faculdade de Medicina, Portugal |
2022/01/18 - 2022/01/19 | BEB Day 2022: The Overview Effect was organized by students from the 16th Edition of PDBEB. This edition addressed current
global issues in a dynamic and interdisciplinary perspective, with special focus on the effects of climate change on health.
Seven lectures from national and international reputed speakers composed the event, a roundtable and a pitch and poster session
presentation supported by Laborders and Bluepharma. (https://www.uc.pt/iii/bebday/bebday2022/) (2022/01/18 - 2022/01/19)
Congress (Member of the Organising Committee)
|
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2022/01/18 - 2022/01/19 | Moderator of the roundtable discussion on "BEB Day 2022: The Overview Effect" conference. This roundtable gathered experts
from different fields such as economy, sociology, law, physics, ecology and biomedicine to discuss the role of science in
finding new strategies to minimize the impact of climate change and pollution in our health and lifestyle, aiming at a sustainable
future for all. (https://www.uc.pt/iii/bebday/bebday2022/) (2022/01/18 - 2022/01/19)
Round table (Other)
|
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2021/04/10 - 2021/04/11 | Tutor of the workshop "Medicinal Plants: The other side of Drugs" at the X In4Med event. (2021/04/10 - 2021/04/11)
Workshop (Other)
|
Universidade de Coimbra Faculdade de Medicina, Portugal |
2018 - 2018 | 1st Drugs R&D PhD Symposium - “Translational Science: From Academia to Industry @ FFUC" (2018 - 2018)
Symposium (Co-organisor)
|
Universidade de Coimbra Faculdade de Farmácia, Portugal |
2007/03 - 2007/03 | Organizer of the FENGE2007 on March 20, 2007, to March 23, 2007, with the function of monitoring laboratory activities at
the event and also to conduct experiments in biology and chemistry from the public event. (2007)
Exhibition (Member of the Organising Committee)
|
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2024/09/27 - Current | European researchers night - Scientific Researcher (Outreach activities along the city of Coimbra (Portugal)).
Exhibition
|
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2023/09/29 - Current | European researchers night - Scientific Researcher (Outreach activities along the city of Coimbra (Portugal)).
Exhibition
|
2023 European researchers' night
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2022 - 2023 | Finalist as a PhD student in the 4th edition of the University of Coimbra Three-Minute Thesis Competition (https://www.uc.pt/en/3mt/3mt-finalists/)
Call
|
|
2022/11 - 2022/11 | i-Days: Student competition to tackle health challenges. i-Days promote health innovation among university students through
dozens of one-day and two-day programs held in academic institutions around Europe. Students from all academic areas receive
an introduction to practical health innovation tools and compete in teams to tackle real-life health challenges posed by EIT
Health, local organizations, private corporations or start-ups.
Workshop
|
EIT Health - Cantanhede Innovation Days 2022
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2022/09/30 - 2022/09/30 | European researchers night - Scientific Researcher (Outreach activities along the city of Coimbra (Portugal)).
Exhibition
|
European Researchers' Night '22'23 Coimbra
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2022/09/30 - 2022/09/30 | European researchers night - Volunteer Staff (Outreach activities along the city of Coimbra (Portugal)).
Exhibition
|
European Researchers' Night '22'23 Coimbra
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2021/09 - 2021/09 | European researchers night - Scientific Researcher
(Outreach activities along the city of Coimbra (Portugal)).
Exhibition
|
2021 European researchers' night
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2021/09 - 2021/09 | European researchers night - Volunteer Staff
(Outreach activities along the city of Coimbra (Portugal)).
Exhibition
|
European researcher's night
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
2018 - 2018 | Viruses and Nucleic Acids
Seminar
|
Universidade de Coimbra Centro de Química de Coimbra, Portugal
|
2018 - 2018 | Invasion and Migration: Imaging cell migration; Invasive migration; and 3D cell culture
Workshop
|
VI Cell Culture and Tissue Training Course
CNC.IBILI, Portugal
|
2017 - 2017 | Author Workshop 'How to write great papers and get published. Understanding and benefiting from the publishing process.' provided
by Elsevier Publishing Campus.
Workshop
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
2016 - 2016 | Online course provided by Coursera platform: Epigenetic Control of Gene Expression
Other
|
The University of Melbourne University College, Australia
|
2014 - 2014 | Online course provided by Miriadax platform: Farmacología Básica
Other
|
Universidad CEU San Pablo, Spain
|
2014 - 2014 | Liposomes encapsulating drug-cyclodextrin complexes aimed for transdermal drug delivery
Seminar
|
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
|
2014 - 2014 | II Iberian Meeting of Toxicology – Clinic Toxicology
Conference
|
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
|
2013 - 2013 | II SPI Workshop Thymus@Porto
Seminar
|
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2010 - 2010 | Meeting of Chemical and Biological Engineering
Meeting
|
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
2010 - 2010 | 'Fourth Annual Workshop on the Business-Government Interface' - Personalized Medicine
Workshop
|
Biocant Associação de Transferência de Tecnologia, Portugal
|
2009 - 2009 | I Meeting of the Chemical and Biological Engineering Department
Meeting
|
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
|
2008 - 2008 | III Meeting of Biological Engineering
Meeting
|
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
Ad Hoc journal article review
Journal title (ISSN) | Publisher | |
---|---|---|
2024/11 - 2024/11 | Molecular Cancer | BioMed Central (BMC) part of Springer Nature |
2020 - 2020 | Journal of Cellular and Molecular Medicine, IF=5.310 (1582-4934) | Wiley (Blackwell Publishing) |
2020 - 2020 | OncoTargets and Therapy, IF=4.147 (1178-6930) | Dove Medical Press |
2018/12 - 2018/12 | Journal of Bone Oncology, IF=4.072 (2212-1374) | Elsevier |
Association member
Society Organization name | Role | |
---|---|---|
2021/12 - Current | ASPIC - Portuguese Association for Cancer Research | |
2021/12 - Current | EACR - European Association for Cancer Research | |
2017 - Current | Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS) |
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2023 - Current | Frontiers in Pharmacology | Frontiers |
2023 - Current | Frontiers in Oncology | Frontiers |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2022/10 - Current | Assessment of the antiproliferative and cytotoxic activity of diterpenes in urothelial bladder cancer cells (MSc. Thesis - Integrated Master's degree in Medicine, University of Coimbra) | Ana Isabel Sousa |
2023/09 - 2024/11 | Antitumoral Potential of Carotenoid-Rich Microalgae Strains (MSc. Thesis - Master degree in Marine Biology, University of Pádova, Italy) | Aryan Guilani |
2024/09/01 - 2024/09/30 | Assessment of natural lead compounds in 3D cell models of Glioblastoma | Maritea Arelic |
2024/02 - 2024/06 | Assessment of the antitumoral effect of diterpenes-based nanosystem in 3D cell model of glioblastoma (Applied Research Discipline - Integrated Master's degree in Medicine, University of Coimbra) | Rita Patacho |
2023/10/23 - 2023/11/17 | Evaluation of the cytotoxic potential of abietane diterpenoids isolated from South African Lamiaceae species in the 639-V cell line (Curricular research internship - MSc. degree in Molecular and Cell Biology (University of Coimbra)) | Gabriela Espírito-Santo |
2023 - 2023 | CôaMedPlants: Evaluation of the cytotoxic effect of Lavandula pedundulata (Mill.) Cav. essential oil in the glioblastoma U87 cell line (BSc. Project - Bachelor in Medicinal Chemistry, Faculty of Sciences and Technology, University of Coimbra) | Catarina Barreiros |
2023 - 2023 | CôaMedPlants: Evaluation of the cytotoxic effect of Mentha cervina L. essential oil in the glioblastoma U87 cell line (BSc. Project - Bachelor in Medicinal Chemistry, Faculty of Sciences and Technology, University of Coimbra) | Maria Sousa |
2023 - 2023 | Evaluation of abietane diterpenes effect in the expression of genes involved in pro-apoptotic mechanisms in glioblastoma U87 cell line (BSc. Project - Bachelor in Biology, Faculty of Sciences and Technology, University of Coimbra) | Carolina Colaço |
2023 - 2023 | Evaluation of the antitumor effect of ayahuasca in glioblastoma cell lines (BSc. Project - Bachelor in Biology, Faculty of Sciences and Technology, University of Coimbra) | Gabriela Espírito-Santo |
2022/05/02 - 2022/07/09 | Glioblastoma: Bioactive potential of essential oils (Curricular research internship - Integrated MSc. degree in Pharmaceutical Sciences (University of Coimbra) | Jéssica Delgado |
2022/03 - 2022/06 | Assessment of the antiproliferative and cytotoxic effect of diterpenes in A172 glioblastoma cell line (Applied Research Discipline - Integrated Master's degree in Medicine, University of Coimbra) | Ana Isabel Sousa |
2022/05 - 2022/05 | Assessment of the bioactivity of essential oils obtained from medicinal plants from Côa Valley in glioblastoma cell lines, the example of Mentha cervina L. (Curricular research internship - MSc. degree in Medicinal Chemistry (University of Coimbra)) | Sandra Carreira |
2022/03 - 2022/05 | Antitumoral effect of plant-based compounds in the treatment of in glioblastoma (Applied Research Discipline - Integrated Master's degree in Medicine, University of Coimbra) | Alexandra Rodrigues |
2021/02/15 - 2021/05/21 | Assessment of the antitumoral effect and mechanism of action of plant-based products in glioblastoma (Applied Research Discipline - Integrated Master's degree in Medicine, University of Coimbra) | Beatriz Mendes |
2017 - 2018 | Synthesis of a nanocarrier based on Pluronic L61 and PEI - (Curricular research internship - Integrated MSc. degree in Pharmaceutical Sciences (Universidad de Alcalá, Madrid-Spain)) | Jorge Santos |
2017 - 2018 | Application of micelleplexes of Pluronic L64-PEI-miR-145 in osteosarcoma therapy (MSc. Thesis - MSc. degree in Medicine Technologies, University of Coimbra) | Mauro Almeida |
2016 - 2018 | Design, optimization, and characterization of a novel nanocarrier based on P103 and PEI (Extracurricular research internship - Integrated MSc. degree in Pharmaceutical Sciences, University of Coimbra) | Jorge Faria |
Distinctions
Other distinction
2022 | Travel Grant
European Society for Clinical Investigation, Netherlands
|
2019 | PhD Scholarship (SFRH/BD/146441/2019)
Fundação para a Ciência e a Tecnologia, Portugal
|