???global.info.a_carregar???
Miguel Cacho Teixeira received BSc and PhD degrees in Chemical Engineering and Biotechnology from the Technical University of Lisbon, Lisbon, Portugal, in 2000 and 2004, respectively. He is currently full professor at the Bioengineering Department of Instituto Superior Técnico (IST), University of Lisbon. He is also senior researcher at iBB - Institute for Bioengineering and Biosciences, Biological Sciences Research Group, IST. His research interests include yeast molecular and cellular biology, response to stress and multidrug resistance (MDR) in S. cerevisiae and in the pathogenic yeasts of the Candida genus, functional genomics, proteomics, and bioinformatics. Since 2002, he has co-authored more than 90 peer-reviewed papers in international scientific journals, 11 book chapters and co-coordinates the public database YEASTRACT+. He has further participated in 19 funded research projects, 5 of which as PI. He has/is also supervised/supervising 5 post-doctoral programs, 9 PhD students and 30 MSc students.
Read full resume ↓
Identification

Personal identification

Full name
Miguel Cacho Teixeira

Citation names

  • Teixeira, Miguel
  • Teixeira, Miguel Cacho

Author identifiers

Ciência ID
C81C-E9C5-8B2F
ORCID iD
0000-0002-5676-6174
Google Scholar ID
Pr5-6TUAAAAJ
Researcher Id
A-3870-2008

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology
  • Engineering and Technology - Industrial Biotechnology
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Medical and Health Sciences - Health Sciences - Infectious Diseases

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2017
Concluded
 Biotechnology and Biosciences (Título de Agregado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"-" (THESIS/DISSERTATION)
 Aprovado
2004
Concluded
 Biotecnologia (Doutoramento)
Major in Sem especialidade
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Molecular Responses to the Herbicide 2,4 - Dichlorophenoxyacetic Acid (2,4-d) in Yeast - from a Gene by Gene Analysys to Global Approaches" (THESIS/DISSERTATION)
2004
Concluded
 PhD in Biotechnology (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Molecular responses to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) in yeast: from a gene by gene analysis to global approaches" (THESIS/DISSERTATION)
 aprovado
2000
Concluded
 Engenharia Química (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (THESIS/DISSERTATION)
 16 valores
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2023/11/01 - Current Full Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/01/30 - 2023/10/31 Associate Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal
2008 - 2018 Assistant Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal

Positions / Appointments

Category
Host institution 		Employer
2021/10/15 - Current Member of the Executive Board of the Pedagogical Council Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/09/01 - Current BSc Degree Coordinator Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09/01 - 2021/08/31 MSc degree co-coordinator Universidade de Lisboa Instituto Superior Técnico, Portugal
Projects

Contract

Designation Funders
2022/12/10 - Current INCORE - Innovation Capacity Building for Higher Education in Europe’s Outermost Regions
1018P.06076.1.01 KIC INCORE
Researcher
Universidade de Lisboa Instituto Superior Técnico, Portugal
Ongoing
2018/10 - 2022/09 MIXED-UP - Targeting pathogenesis and engineering cell factories: by developing mixed regulatory-metabolic genomic models in yeasts
PTDC/BII-BIO/28216/2017
Principal investigator
Fundação para a Ciência e a Tecnologia
2019/09 - 2021/12 Sustainable production of bioactive metabolites from microbial symbionts of marine sponges and corals
FA05-2017-032
 Direção-Geral de Política do Mar - Fundo Azul - Blue Biotechnology (Lisboa)
2018/06 - 2021/06 BioData.pt - Portuguese Biological Data Network
LISBOA-01-0145-FEDER-022231
 Programa Operacional Regional de Lisboa 2020
2016/01 - 2018/12 Deciphering the mechanisms of transcriptional regulation that control antifungal drug resistance in the pathogenic yeast Candida glabrata: aiming the development of improved diagnosis and therapeutic approaches
Provided by PTCRIS: 142635
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2014/04 - 2015/03 Major Facilitator Superfamily transporters in the context of modern agriculture constraints: exploratory studies
Provided by PTCRIS: 134038
134038
 Fundação para a Ciência e a Tecnologia, I.P.
2012/02 - 2015/02 FUNDRING: Identification of new biomarkers of antiFUNgal Drug Resistance diagnosis IN Candida Glabrata: the particular role of multidrug resistance transporters
Provided by PTCRIS: 119356
119356
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2011/03 - 2014/07 ERA-NET Integral Engineering of Acetic Acid Tolerance in Yeast (INTACT)
Provided by PTCRIS: 116749
116749
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04/01 - 2013/09/30 ZygoSacAR-Mecanismos de resistência a ácidos fracos em leveduras contaminantes alimentares: do modelo experimental Saccharomyces cerevisiae a Zygosaccharomyces spp
PTDC/AGR-ALI/102608/2008
Universidade do Minho, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/09 Resistance to pesticides and other chemical stresses of agricultural interest: Role of plant Major Facilitator Superfamily transporters
Provided by PTCRIS: 102967
102967
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04 - 2013/09 QCMTF-Biosensor platform for transcription factor DNA binding activity detection
Provided by PTCRIS: 108517
108517
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04 - 2013/09 ZygoSacAR-Mechanistic insights into acetic acid resistance in food spoilage yeasts: from the experimental model Saccharomyces cerevisiae to Zygosaccharomyces spp
Provided by PTCRIS: 102608
102608
 Fundação para a Ciência e a Tecnologia, I.P.
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 23 - 2011-2012
PEst-OE/EQB/LA0023/2011
Universidade do Minho, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade do Algarve, Portugal

Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Fundação Gaspar Frutuoso, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade dos Açores, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009/01/01 - 2011/12/31 Implementation of a Nacional Facility for DNA Microarrays: Phase II
PTDC/BIA-BCM/64745/2006
Universidade de Aveiro, Portugal

Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/06 - 2011/12 Functional and biochemical analysis of the yeast multidrug resistance transporters Qdr2 and Aqr1
67722
Provided by PTCRIS: 67722
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2008/01 - 2011/02 IMATINIB RESISTANCE AND TARGETS IN CHRONIC MYELOID LEUKAEMIA: POST-GENOMIC APPROACHES USING YEAST AS MODEL SYSTEM
71760
Provided by PTCRIS: 71760
 Fundação para a Ciência e a Tecnologia, I.P.
2008/01/01 - 2010/12/31 Dyablo: Modelos para o Comportamento Dinâmico de Redes Biológicas
PTDC/EIA/71587/2006
Universidade de Lisboa Instituto Superior Técnico, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/01 - 2010/12 Dyablo: Models for the Dynamic Behavior of Biological Networks
71587
Provided by PTCRIS: 71587
 Fundação para a Ciência e a Tecnologia, I.P.
2007/09 - 2010/11 Characterization and modeling of a specific transcriptional regulatory network required for multidrug resistance in yeast.
Provided by PTCRIS: 72063
72063
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2007/09 - 2010/11 PROBIOETHANOL - Proteomics and engineering of yeast ethanol tolerance for high-productivity bio-ethanol fermentation processes
66151
Provided by PTCRIS: 66151
 Fundação para a Ciência e a Tecnologia, I.P.
2007/07 - 2010/06 Herbicide resistance in Arabidopsis thaliana: Role of plant multidrug resistance transporters
Provided by PTCRIS: 67858
67858
 Fundação para a Ciência e a Tecnologia, I.P.
2006/01/02 - 2008/01/01 Elucidação das complexas redes de regulação que actuam na levedura sujeita a drogas/stresse químico: abordagens de expressão genómica e de bioinformática
PDCT/BIO/56838/2004
Universidade de Lisboa Instituto Superior Técnico, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2006/01 - 2008/01 Insights into the complex regulatory networks acting in yeast cells challenged with drugs/chemical stresses: genome-wide expression approaches supported by bioinformatics
Provided by PTCRIS: 56838
56838
 Fundação para a Ciência e a Tecnologia, I.P.
2005/01/01 - 2007/12/31 DBYeast: Infraestruturas e algoritmos para análise e identificação de redes de regulação genética
POSC/EIA/57398/2004
Universidade de Lisboa Instituto Superior Técnico, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/01 - 2007/12 DBYeast: Infrastructures and algorithms for analysis and identification of gene regulatory networks
Provided by PTCRIS: 57398
57398
 Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Book chapter
  1. Teixeira, Miguel Cacho. "Host-Induced Stress Response in Human Pathogenic Fungi". 2021.
    10.1016/B978-0-12-819990-9.00035-4
  2. Pais, Pedro; Galocha, Mónica; Teixeira, Miguel Cacho. "Genome-Wide Response to Drugs and Stress in the Pathogenic Yeast Candida glabrata". In Progress in Molecular and Subcellular Biology, 155-193. Springer International Publishing, 2019.
    10.1007/978-3-030-13035-0_7
  3. Cavalheiro, Mafalda; Teixeira, Miguel Cacho. "In the Crossroad Between Drug Resistance and Virulence in Fungal Pathogens". In Stress Response Mechanisms in Fungi, 223-259. Springer International Publishing, 2018.
    Published • 10.1007/978-3-030-00683-9_7
  4. Frazao, L.; Santos, R.; Teixeira, M.C.; Theera-Umpon, N.; Auephanwiriyakul, S.. "Automatic detection of yeast and pseudohyphal form cells in the human pathogen candida glabrata". 2015.
    10.1007/978-3-319-22053-6_69
  5. Mira, N.P.; Teixeira, M.C.; Sá-Correia, I.. "Characterization of complex regulatory networks and identification of promoter regulatory elements in yeast: "In Silico" and "wet-Lab" approaches". 2012.
    10.1007/978-1-61779-376-9_2
  6. Teixeira, Miguel Cacho. "Complex regulatory interplay between multidrug resistance and oxidative stress response in yeast: the FLR1 regulatory network as a systems biology case-study". 2012.
    10.5772/32603
  7. Cabrito, Tnia; Remy, Estelle; Teixeira, Miguel; Duque, Paula; S-correi, Isabel. "Resistance to Herbicides in the Model Organisms Saccharomyces cerevisiae and Arabidopsis thaliana: the Involvement of Multidrug Resistance Transporters". In Herbicides and Environment. InTech, 2011.
    10.5772/13057
Conference paper
  1. Torres, F., Santos, A.M., Elias, A., Teixeira, M.C., Montemor, M.F. "Tackling perception and deception in STEM: A critical thinking skill for early-career development". Paper presented in European Society for Engineering Education (SEFI) 2022 Annual Conference, Barcelona, 2022.
    Published
  2. Viana, Romeu; Dias, Oscar; Bastos, José; Lagoa, Davide Rafael Santos; Galocha, Mónica; Rocha, I.; Teixeira, Miguel Cacho. "Genome-scale metabolic model of the human pathogen C. albicans: aiming the identification of promising new drug targets". 2019.
  3. Dos Santos, S.C.; Teixeira, M.C.; Mira, N.P.; Cabrito, T.R.; Palma, M.; Lourenço, A.B.; Dias, P.J.; et al. "Response and resistance to drugs and chemical stress in the yeast model: A genome-wide view". 2011.
    10.1109/ENBENG.2011.6026076
  4. Dias, P.J.; Costa, C.P.; Sá-Correia, I.; Teixeira, M.C.; Monteiro, P.T.; Oliveira, A.L.; Freitas, A.T.. "Using systems biology approaches to study a multidrug resistance network". 2011.
    10.1109/ENBENG.2011.6026073
  5. Freitas, A.T.; Ramalho, A.P.; Oliveira, C.A.; Nogueira, C.S.; Teixeira, Miguel Cacho; Isabel Sá-Correia; Oliveira, A.L.. "Identification of cooperative mechanisms in transcription regulatory networks using non-supervised learning techniques". Paper presented in In proceedings of the 2nd Workshop on Data Mining in Functional Genomics and Proteomics, ECML/PKDD, 2007.
    Published
  6. Teixeira, Miguel Cacho; Monteiro, P.; Jain, P.; Fernandes, A.R.; Mira, N.P.; Alenquer, M.; Freitas, A.T.; et al. "YEASTRACT: a database to search for transcription regulatory associations in Saccharomyces cerevisiae". Paper presented in XXII International Conference on Yeast Genetics and Molecular Biology, Bratislava, Slovak Republic, Bratislava, 2005.
    Published
  7. Viegas, C.A.; Tenreiro, S.; Neves, M.S.; Nunes, P.A.; Teixeira, Miguel Cacho; Cabral, M.G.; Isabel Sá-Correia. "Role of ORF YNL065w (BZR1 gene), encoding a plasma membrane MFS transporter required for multidrug resistance, on S. cerevisiae adaptation to benzoic acid". Paper presented in Federation of European Biochemical Societies, 2001.
  8. Nunes, P.A.; Tenreiro, S.; Teixeira, Miguel Cacho; Isabel Sá-Correia; Sá-Correia, I.. "Resistance and Adaptation to Quinidine in Saccharomyces cerevisiae: Role of QDR1 (YIL120w), Encoding a Plasma Membrane Transporter of the Major Facilitator Superfamily Required for Multidrug Resistance". Paper presented in Federation of European Biochemical Societies, 2001.
    10.1128/AAC.45.5.1528-1534.2001
Conference poster
  1. Fonseca, Ana; Monteiro, Pedro T; Teixeira, Miguel Cacho; Chaouiya, Claudine. "Towards Genome-Scale Regulated Metabolic Models in Yeast". Paper presented in Networks and Molecular Biology - Research School, 2020.
  2. Fonseca, Ana; Monteiro, Pedro T; Teixeira, Miguel Cacho; Chaouiya, Claudine. "Genome-Scale Logical Regulatory Models for S. cerevisiae, C. albicans and C. glabrata". Paper presented in CompSysBio - Advanced Lecture Course on Computational Systems Biology, 2019.
  3. Pais, Pedro; Galocha, M; Califórnia, R; Pimenta, Andreia I.; Mil-Homens, Dalila; Fialho, Arsénio; Butler, G; Teixeira, Miguel Cacho. "Functional characterization of the transcription factor CgMrr1 suggests new players governing azole drug resistance in Candida glabrata". Paper presented in 14th ASM Conference on Candida and Candidiasis, 2018.
Journal article
  1. Romeu Viana; Tiago Carreiro; Diogo Couceiro; Oscar Dias; Isabel Rocha; Miguel Cacho Teixeira. "Metabolic reconstruction of the human pathogen Candida auris: using a cross-species approach for drug target prediction". FEMS Yeast Research (2023): https://doi.org/10.1093/femsyr/foad045.
    10.1093/femsyr/foad045
  2. Michiyo Okamoto; Keiko Nakano; Azusa Takahashi-Nakaguchi; Kaname Sasamoto; Masashi Yamaguchi; Miguel Cacho Teixeira; Hiroji Chibana. "In Candida glabrata, ERMES Component GEM1 Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility". Journal of Fungi (2023): https://doi.org/10.3390/jof9020240.
    10.3390/jof9020240
  3. João F. Almeida; Matilde Marques; Vanessa Oliveira; Conceição Egas; Dalila Mil-Homens; Romeu Viana; Daniel F. R. Cleary; et al. "Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens". Marine Drugs (2022): https://doi.org/10.3390/md21010034.
    10.3390/md21010034
  4. Pedro Pais; Mónica Galocha; Azusa Takahashi-Nakaguchi; Hiroji Chibana; Miguel C. Teixeira. "Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants". Microbial Cell (2022): https://doi.org/10.15698/mic2022.11.786.
    10.15698/mic2022.11.786
  5. Mónica Galocha; Romeu Viana; Pedro Pais; Ana Silva-Dias; Mafalda Cavalheiro; Isabel M. Miranda; Mieke Van Ende; et al. "Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation". Communications Biology 5 1 (2022): http://dx.doi.org/10.1038/s42003-022-04087-0.
    10.1038/s42003-022-04087-0
  6. Carol A Munro; Miguel C Teixeira. "Yeast pathogenesis and drug resistance: the beauty of the BYeast". FEMS Yeast Research (2022): https://doi.org/10.1093/femsyr/foac029.
    10.1093/femsyr/foac029
  7. Sandra Godinho Silva; Patrícia Paula; José Paulo da Silva; Dalila Mil-Homens; Miguel Cacho Teixeira; Arsénio Mendes Fialho; Rodrigo Costa; Tina Keller-Costa. "Insights into the Antimicrobial Activities and Metabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) Species from the Rare Marine Biosphere". Marine Drugs (2022): https://doi.org/10.3390/md20070423.
    10.3390/md20070423
  8. "Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata". Frontiers in Cell and Developmental Biology 10 (2022): http://dx.doi.org/10.3389/fcell.2022.820675.
    10.3389/fcell.2022.820675
  9. Romeu Viana; Diogo Couceiro; Tiago Carreiro; Oscar Dias; Isabel Rocha; Miguel Cacho Teixeira. "A Genome-Scale Metabolic Model for the Human Pathogen Candida Parapsilosis and Early Identification of Putative Novel Antifungal Drug Targets". Genes 13 2 (2022): 303-303. https://doi.org/10.3390/genes13020303.
    10.3390/genes13020303
  10. Pedro Pais; Mónica Galocha; Raquel Califórnia; Romeu Viana; Mihaela Ola; Michiyo Okamoto; Hiroji Chibana; Geraldine Butler; Miguel C. Teixeira. "Characterization of the Candida glabrata Transcription Factor CgMar1: Role in Azole Susceptibility". Journal of Fungi (2022): https://doi.org/10.3390/jof8010061.
    10.3390/jof8010061
  11. Teixeira, Miguel Cacho. "From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view". Communications Biology 4 1 (2021): http://dx.doi.org/10.1038/s42003-021-02412-7.
    10.1038/s42003-021-02412-7
  12. Jorge Oliveira; Miguel Antunes; Claudia P. Godinho; Miguel C. Teixeira; Isabel Sá-Correia; Pedro T. Monteiro. "From a genome assembly to full regulatory network prediction: the case study of Rhodotorula toruloides putative Haa1-regulon". BMC Bioinformatics (2021): https://doi.org/10.1186/s12859-021-04312-3.
    10.1186/s12859-021-04312-3
  13. Cláudia P Godinho; Margarida Palma; Jorge Oliveira; Marta N Mota; Miguel Antunes; Miguel C Teixeira; Pedro T Monteiro; Isabel Sá-Correia. "The N.C.Yeastract and CommunityYeastract databases to study gene and genomic transcription regulation in non-conventional yeasts". FEMS Yeast Research (2021): https://doi.org/10.1093/femsyr/foab045.
    10.1093/femsyr/foab045
  14. Teixeira, Miguel Cacho. "Role of CgTpo4 in Polyamine and Antimicrobial Peptide Resistance: Determining Virulence in Candida glabrata". International journal of molecular sciences (2021): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866538/?tool=EBI.
  15. Sophie Klemm; Martina Baum; Haoyi Qiu; Zibin Nan; Mafalda Cavalheiro; Miguel Cacho Teixeira; Claire Tendero; et al. "Development of Polythiourethane/ZnO-Based Anti-Fouling Materials and Evaluation of the Adhesion of Staphylococcus aureus and Candida glabrata Using Single-Cell Force Spectroscopy". Nanomaterials 11 2 (2021): 271-271. https://doi.org/10.3390/nano11020271.
    10.3390/nano11020271
  16. Teixeira, Miguel Cacho. "Transcriptome-wide differences between Saccharomyces cerevisiae and Saccharomyces cerevisiae var. boulardii: Clues on host survival and probiotic activity based on promoter sequence variability.". Genomics (2021): https://doi.org/10.1016/j.ygeno.2020.11.034.
    10.1016/j.ygeno.2020.11.034
  17. Teixeira, Miguel Cacho. "A new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: The transcription factor CgTog1.". Virulence (2020): https://europepmc.org/articles/PMC7605352.
    10.1080/21505594.2020.1839231
  18. Mónica Galocha; Inês Vieira Costa; Miguel Cacho Teixeira. "Carrier-Mediated Drug Uptake in Fungal Pathogens". Genes (2020): https://doi.org/10.3390/genes11111324.
    10.3390/genes11111324
  19. Teixeira, Miguel Cacho. "Assessing regulatory features of the current transcriptional network of Saccharomyces cerevisiae.". Scientific reports (2020): https://europepmc.org/articles/PMC7575604.
    10.1038/s41598-020-74043-7
  20. Romeu Viana; Oscar Dias; Davide Lagoa; Mónica Galocha; Isabel Rocha; Miguel Cacho Teixeira. "Genome-Scale Metabolic Model of the Human Pathogen Candida albicans: A Promising Platform for Drug Target Prediction". Journal of Fungi 6 3 (2020): 171-171. https://doi.org/10.3390/jof6030171.
    10.3390/jof6030171
  21. Pedro Pais; Raquel Califórnia; Mónica Galocha; Romeu Viana; Mihaela Ola; Mafalda Cavalheiro; Azusa Takahashi-Nakaguchi; et al. "Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance Through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability". Antimicrobial Agents and Chemotherapy (2020): https://doi.org/10.1128/AAC.00554-20.
    10.1128/AAC.00554-20
  22. Pedro Pais; Vanda Almeida; Melike Yilmaz; Miguel C. Teixeira. "Saccharomyces boulardii: What Makes It Tick as Successful Probiotic?". Journal of Fungi (2020): https://doi.org/10.3390/jof6020078.
    10.3390/jof6020078
  23. Teixeira, Miguel Cacho. "Screening the Drug:H+ Antiporter Family for a Role in Biofilm Formation in Candida glabrata.". Frontiers in cellular and infection microbiology (2020): https://europepmc.org/articles/PMC7010593.
    10.3389/fcimb.2020.00029
  24. Teixeira, Miguel Cacho. "YEASTRACT+: a portal for cross-species comparative genomics of transcription regulation in yeasts.". Nucleic acids research (2020): https://europepmc.org/articles/PMC6943032.
    10.1093/nar/gkz859
  25. Pedro Pais; Mónica Galocha; Isabel M. Miranda; Acácio G. Rodrigues; Miguel C. Teixeira; Vincent Bruno. "Draft Genome Sequences of Three Clinical Isolates of the Pathogenic Yeast Candida glabrata". Microbiology Resource Announcements (2019): https://doi.org/10.1128/MRA.00278-19.
    10.1128/MRA.00278-19
  26. Mónica Galocha; Pedro Pais; Mafalda Cavalheiro; Diana Pereira; Romeu Viana; Miguel C. Teixeira. "Divergent Approaches to Virulence in C. albicans and C. glabrata: Two Sides of the Same Coin". International Journal of Molecular Sciences 20 9 (2019): 2345-2345. https://doi.org/10.3390/ijms20092345.
    10.3390/ijms20092345
  27. Cavalheiro, M.; Teixeira, M.C.. "Candida Biofilms: Threats, challenges, and promising strategies". Frontiers in Medicine 5 FEB (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85049957985&partnerID=MN8TOARS.
    10.3389/fmed.2018.00028
  28. Cavalheiro, M.; Pais, P.; Galocha, M.; Teixeira, M.C.. "Host-pathogen interactions mediated by MDR transporters in fungi: As pleiotropic as it gets!". Genes 9 7 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85049975078&partnerID=MN8TOARS.
    10.3390/genes9070332
  29. Teixeira, M.C.; Monteiro, P.T.; Palma, M.; Costa, C.; Godinho, C.P.; Pais, P.; Cavalheiro, M.; et al. "YEASTRACT: An upgraded database for the analysis of transcription regulatory networks in Saccharomyces cerevisiae". Nucleic Acids Research 46 D1 (2018): D348-D353. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040917545&partnerID=MN8TOARS.
    10.1093/nar/gkx842
  30. Estelle Remy; María Niño-González; Cláudia P. Godinho; Tânia R. Cabrito; Miguel C. Teixeira; Isabel Sá-Correia; Paula Duque. "Heterologous expression of the yeast Tpo1p or Pdr5p membrane transporters in Arabidopsis confers plant xenobiotic tolerance". Scientific Reports (2017):
    10.1038/s41598-017-04534-7
  31. Rui Santos; Catarina Costa; Dalila Mil-Homens; Daniela Romão; Carla C.C.R. de Carvalho; Pedro Pais; Nuno P. Mira; Arsénio M. Fialho; Miguel C. Teixeira. "The multidrug resistance transporters CgTpo1_1 and CgTpo1_2 play a role in virulence and biofilm formation in the human pathogen Candida glabrata". Cellular Microbiology (2017): e12686-e12686. https://doi.org/10.1111%2Fcmi.12686.
    10.1111/cmi.12686
  32. Godinho, C.P.; Mira, N.P.; Cabrito, T.R.; Teixeira, M.C.; Alasoo, K.; Guerreiro, J.F.; Sá-Correia, I.. "Yeast response and tolerance to benzoic acid involves the Gcn4- and Stp1-regulated multidrug/multixenobiotic resistance transporter Tpo1". Applied Microbiology and Biotechnology 101 12 (2017): 5005-5018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017477581&partnerID=MN8TOARS.
    10.1007/s00253-017-8277-6
  33. Romão D; Cavalheiro M; Mil-Homens D; Santos R; Pais P; Costa C; Takahashi-Nakaguchi A; et al. "A New Determinant of Candida glabrata Virulence: The Acetate Exporter CgDtr1.". Frontiers in cellular and infection microbiology (2017): http://europepmc.org/abstract/med/29184852.
    10.3389/fcimb.2017.00473
  34. Monteiro, P.T.; Pais, P.; Costa, C.; Manna, S.; Sa-Correia, I.; Teixeira, M.C.; Monteiro PT; et al. "The PathoYeastract database: An information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts". Nucleic Acids Research 45 D1 (2017): D597-D603. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016147595&partnerID=MN8TOARS.
    10.1093/nar/gkw817
  35. Pereira, F.B.; Teixeira, M.C.; Mira, N.P.; Sá-Correia, I.; Domingues, L.. "Genome-wide screening of Saccharomyces cerevisiae genes required to foster tolerance towards industrial wheat straw hydrolysates". Journal of Industrial Microbiology and Biotechnology 41 12 (2016): 1753-1761. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929941635&partnerID=MN8TOARS.
    10.1007/s10295-014-1519-z
  36. Pais, P.; Costa, C.; Cavalheiro, M.; Romão, D.; Teixeira, M.C.. "Transcriptional control of drug resistance, virulence and immune system evasion in pathogenic fungi: A cross-species comparison". Frontiers in Cellular and Infection Microbiology 6 OCT (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84997078100&partnerID=MN8TOARS.
    10.3389/fcimb.2016.00131
  37. Pais, P.; Pires, C.; Costa, C.; Okamoto, M.; Chibana, H.; Teixeira, M.C.. "Membrane proteomics analysis of the Candida glabrata response to 5-flucytosine: Unveiling the role and regulation of the drug efflux transporters CgFlr1 and CgFlr2". Frontiers in Microbiology 7 DEC (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85009348520&partnerID=MN8TOARS.
    10.3389/fmicb.2016.02045
  38. Costa C; Ribeiro J; Miranda IM; Silva-Dias A; Cavalheiro M; Costa-de-Oliveira S; Rodrigues AG; Teixeira MC. "Clotrimazole Drug Resistance in Candida glabrata Clinical Isolates Correlates with Increased Expression of the Drug:H(+) Antiporters CgAqr1, CgTpo1_1, CgTpo3, and CgQdr2.". (2016): http://europepmc.org/abstract/med/27148215.
    10.3389/fmicb.2016.00526
  39. Teixeira MC; Monteiro PT; Sá-Correia I. "Predicting Gene and Genomic Regulation in Saccharomyces cerevisiae, using the YEASTRACT Database: A Step-by-Step Guided Analysis.". (2016): http://europepmc.org/abstract/med/26483034.
    10.1007/978-1-4939-3079-1_22
  40. Pais, P.; Costa, C.; Pires, C.; Shimizu, K.; Chibana, H.; Teixeira, M.C.; Pais P; et al. "Membrane proteome-wide response to the antifungal drug clotrimazole in Candida glabrata: Role of the transcription factor CgPdr1 and the Drug:H+ antiporters CgTpo1-1 and CgTpo1-2". Molecular and Cellular Proteomics 15 1 (2016): 57-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955490877&partnerID=MN8TOARS.
    10.1074/mcp.M114.045344
  41. Remy E; Cabrito TR; Batista RA; Teixeira MC; Sá-Correia I; Duque P. "The major facilitator superfamily transporter ZIFL2 modulates cesium and potassium homeostasis in Arabidopsis.". (2015): http://europepmc.org/abstract/med/25378686.
    10.1093/pcp/pcu157
  42. Costa C; Ponte A; Pais P; Santos R; Cavalheiro M; Yaguchi T; Chibana H; Teixeira MC. "New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae.". (2015): http://europepmc.org/abstract/med/26267134.
    10.1371/journal.pone.0135110
  43. Costa, C.; Nunes, J.; Henriques, A.; Mira, N.P.; Nakayama, H.; Chibana, H.; Teixeira, M.C.. "Candida glabrata drug:H+ antiporter CgTpo3 (ORF CAGL0I10384G): Role in azole drug resistance and polyamine homeostasis". Journal of Antimicrobial Chemotherapy 69 7 (2014): 1767-1776. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900994539&partnerID=MN8TOARS.
    10.1093/jac/dku044
  44. dos Santos, S.C.; Teixeira, M.C.; Dias, P.J.; Sá-Correia, I.. "MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: Understanding their physiological function through post-genomic approaches". Frontiers in Physiology 5 MAY (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84904346383&partnerID=MN8TOARS.
    10.3389/fphys.2014.00180
  45. Remy, E.; Cabrito, T.R.; Batista, R.A.; Hussein, M.A.M.; Teixeira, M.C.; Athanasiadis, A.; Sá-Correia, I.; Duque, P.. "Intron Retention in the 5'UTR of the Novel ZIF2 Transporter Enhances Translation to Promote Zinc Tolerance in Arabidopsis". PLoS Genetics 10 5 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901645385&partnerID=MN8TOARS.
    10.1371/journal.pgen.1004375
  46. Teixeira, M.C.; Monteiro, P.T.; Guerreiro, J.F.; Gonçalves, J.P.; Mira, N.P.; Dos Santos, S.C.; Cabrito, T.R.; et al. "The YEASTRACT database: An upgraded information system for the analysis of gene and genomic transcription regulation in Saccharomyces cerevisiae". Nucleic Acids Research 42 D1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84891806965&partnerID=MN8TOARS.
    10.1093/nar/gkt1015
  47. Costa, C.; Dias, P.J.; Sá-Correia, I.; Teixeira, M.C.. "MFS multidrug transporters in pathogenic fungi: Do they have real clinical impact?". Frontiers in Physiology 5 MAY (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84904306087&partnerID=MN8TOARS.
    10.3389/fphys.2014.00197
  48. Lourenço, A.B.; Roque, F.C.; Teixeira, M.C.; Ascenso, J.R.; Sá-Correia, I.. "Quantitative1H-NMR-Metabolomics Reveals Extensive Metabolic Reprogramming and the Effect of the Aquaglyceroporin FPS1 in Ethanol-Stressed Yeast Cells". PLoS ONE 8 2 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84873621089&partnerID=MN8TOARS.
    10.1371/journal.pone.0055439
  49. Remy, E.; Cabrito, T.R.; Baster, P.; Batista, R.A.; Teixeira, M.C.; Friml, J.; Sá-Correia, I.; Duque, P.. "A Major Facilitator Superfamily transporter plays a dual role in polar auxin transport and drought stress tolerance in Arabidopsis". Plant Cell 25 3 (2013): 901-926. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876774810&partnerID=MN8TOARS.
    10.1105/tpc.113.110353
  50. Mira, N.P.; Teixeira, M.C.. "Microbial mechanisms of tolerance to weak acid stress". Frontiers in Microbiology 4 DEC (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84892156556&partnerID=MN8TOARS.
    10.3389/fmicb.2013.00416
  51. Costa, C.; Pires, C.; Cabrito, T.R.; Renaudin, A.; Ohno, M.; Chibana, H.; Sá-Correia, I.; Teixeira, M.C.. "Candida glabrata drug: H+ antiporter CgQdr2 confers imidazole drug resistance, being activated by transcription factor CgPdr1". Antimicrobial Agents and Chemotherapy 57 7 (2013): 3159-3167. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879011813&partnerID=MN8TOARS.
    10.1128/AAC.00811-12
  52. Costa, C.; Henriques, A.; Pires, C.; Nunes, J.; Ohno, M.; Chibana, H.; Sá-Correia, I.; Teixeira, M.C.. "The dual role of Candida glabrata drug: H+ antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance". Frontiers in Microbiology 4 JUN (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84884217577&partnerID=MN8TOARS.
    10.3389/fmicb.2013.00170
  53. Teixeira, M.C.; Godinho, C.P.; Cabrito, T.R.; Mira, N.P.; Sá-Correia, I.. "Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation". Microbial Cell Factories 11 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84864190737&partnerID=MN8TOARS.
    10.1186/1475-2859-11-98
  54. dos Santos, S.C.; Teixeira, M.C.; Cabrito, T.R.; Sá-Correia, I.. "Yeast toxicogenomics: Genome-wide responses to chemical stresses with impact in environmental health, pharmacology, and biotechnology". Frontiers in Genetics 3 APR (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865480260&partnerID=MN8TOARS.
    10.3389/fgene.2012.00063
  55. Remy, E.; Cabrito, T.R.; Batista, R.A.; Teixeira, M.C.; Sá-Correia, I.; Duque, P.. "The Pht1;9 and Pht1;8 transporters mediate inorganic phosphate acquisition by the Arabidopsis thaliana root during phosphorus starvation". New Phytologist 195 2 (2012): 356-371. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862537978&partnerID=MN8TOARS.
    10.1111/j.1469-8137.2012.04167.x
  56. Cabrito, T.R.; Teixeira, M.C.; Singh, A.; Prasad, R.; Sá-Correia, I.. "The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance". Biochemical Journal 440 2 (2011): 195-202. http://www.scopus.com/inward/record.url?eid=2-s2.0-81155123735&partnerID=MN8TOARS.
    10.1042/BJ20110876
  57. Pereira, F.B.; Guimarães, P.M.R.; Gomes, D.G.; Mira, N.P.; Teixeira, M.C.; Sá-Correia, I.; Domingues, L.. "Identification of candidate genes for yeast engineering to improve bioethanol production in very high gravity and lignocellulosic biomass industrial fermentations". Biotechnology for Biofuels 4 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-83055187798&partnerID=MN8TOARS.
    10.1186/1754-6834-4-57
  58. Monteiro, P.T.; Dias, P.J.; Ropers, D.; Oliveira, A.L.; Sá-Correia, I.; Teixeira, M.C.; Freitas, A.T.. "Qualitative modelling and formal verification of the FLR1 gene mancozeb response in Saccharomyces cerevisiae". IET Systems Biology 5 5 (2011): 308-316. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054711652&partnerID=MN8TOARS.
    10.1049/iet-syb.2011.0001
  59. Gonçalves, J.P.; Francisco, A.P.; Mira, N.P.; Teixeira, M.C.; Sá-Correia, I.; Oliveira, A.L.; Madeira, S.C.. "TFRank: Network-based prioritization of regulatory associations underlying transcriptional responses". Bioinformatics 27 22 (2011): 3149-3157. http://www.scopus.com/inward/record.url?eid=2-s2.0-80755171153&partnerID=MN8TOARS.
    10.1093/bioinformatics/btr546
  60. Abdulrehman, D.; Monteiro, P.T.; Teixeira, M.C.; Mira, N.P.; Lourenço, A.B.; Dos Santos, S.C.; Cabrito, T.R.; et al. "YEASTRACT: Providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface". Nucleic Acids Research 39 SUPPL. 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-78651272522&partnerID=MN8TOARS.
    10.1093/nar/gkq964
  61. Teixeira, M.C.; Mira, N.P.; Sá-Correia, I.. "A genome-wide perspective on the response and tolerance to food-relevant stresses in Saccharomyces cerevisiae". Current Opinion in Biotechnology 22 2 (2011): 150-156. http://www.scopus.com/inward/record.url?eid=2-s2.0-79954414844&partnerID=MN8TOARS.
    10.1016/j.copbio.2010.10.011
  62. Mira, N.P.; Henriques, S.F.; Keller, G.; Teixeira, M.C.; Matos, R.G.; Arraiano, C.M.; Winge, D.R.; Sá-Correia, I.. "Identification of a DNA-binding site for the transcription factor Haa1, required for Saccharomyces cerevisiae response to acetic acid stress". Nucleic Acids Research 39 16 (2011): 6896-6907. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052432738&partnerID=MN8TOARS.
    10.1093/nar/gkr228
  63. Teixeira, M.C.; Dias, P.J.; Monteiro, P.T.; Sala, A.; Oliveira, A.L.; Freitas, A.T.; Sá-Correia, I.. "Refining current knowledge on the yeast FLR1 regulatory network by combined experimental and computational approaches". Molecular BioSystems 6 12 (2010): 2471-2481. http://www.scopus.com/inward/record.url?eid=2-s2.0-78149432402&partnerID=MN8TOARS.
    10.1039/c004881j
  64. Teixeira, M.C.; Raposo, L.R.; Palma, M.; Sá-Correia, I.. "Identification of genes required for maximal tolerance to high-glucose concentrations, as those present in industrial alcoholic fermentation media, through a chemogenomics approach". OMICS A Journal of Integrative Biology 14 2 (2010): 201-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950803872&partnerID=MN8TOARS.
    10.1089/omi.2009.0149
  65. Mira, N.P.; Teixeira, M.C.; Sá-Correia, I.. "Adaptive response and tolerance to weak acids in Saccharomyces cerevisiae: A genome-wide view". OMICS A Journal of Integrative Biology 14 5 (2010): 525-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958162502&partnerID=MN8TOARS.
    10.1089/omi.2010.0072
  66. Teixeira, M.C.; Cabrito, T.R.; Hanif, Z.M.; Vargas, R.C.; Tenreiro, S.; Sá-Correia, I.. "Yeast response and tolerance to polyamine toxicity involving the drug: H + antiporter Qdr3 and the transcription factors Yap1 and Gcn4". Microbiology 157 4 (2010): 945-956. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953680750&partnerID=MN8TOARS.
    10.1099/mic.0.043661-0
  67. S-Correia, I.; Teixeira, M.C.. "2D electrophoresis-based expression proteomics: A microbiologists perspective". Expert Review of Proteomics 7 6 (2010): 943-953. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650492407&partnerID=MN8TOARS.
    10.1586/epr.10.76
  68. Madeira, S.C.; Teixeira, M.C.; Sá-Correia, I.; Oliveira, A.L.. "Identification of regulatory modules in time series gene expression data using a linear time biclustering algorithm". IEEE/ACM Transactions on Computational Biology and Bioinformatics 7 1 (2010): 153-165. http://www.scopus.com/inward/record.url?eid=2-s2.0-76849109141&partnerID=MN8TOARS.
    10.1109/TCBB.2008.34
  69. Dias, P.J.; Teixeira, M.C.; Telo, J.P.; Sá-Correia, I.. "Insights into the mechanisms of toxicity and tolerance to the agricultural fungicide mancozeb in yeast, as suggested by a chemogenomic approach". OMICS A Journal of Integrative Biology 14 2 (2010): 211-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950829369&partnerID=MN8TOARS.
    10.1089/omi.2009.0134
  70. Teixeira, M.C.; Santos, P.M.; Rodrigues, C.; Sá-Correia, I.. "Teaching expression proteomics: From the wet-lab to the laptop". Biochemistry and Molecular Biology Education 37 5 (2009): 279-286. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349855060&partnerID=MN8TOARS.
    10.1002/bmb.20315
  71. Cabrito, T.R.; Teixeira, M.C.; Duarte, A.A.; Duque, P.; Sá-Correia, I.. "Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast". Applied Microbiology and Biotechnology 84 5 (2009): 927-936. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349234202&partnerID=MN8TOARS.
    10.1007/s00253-009-2025-5
  72. Sá-Correia, I.; dos Santos, S.C.; Teixeira, M.C.; Cabrito, T.R.; Mira, N.P.. "Drug:H+ antiporters in chemical stress response in yeast". Trends in Microbiology 17 1 (2009): 22-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149316028&partnerID=MN8TOARS.
    10.1016/j.tim.2008.09.007
  73. Teixeira, M.C.; Raposo, L.R.; Mira, N.P.; Lourenço, A.B.; Sá-Correia, I.. "Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol". Applied and Environmental Microbiology 75 18 (2009): 5761-5772. http://www.scopus.com/inward/record.url?eid=2-s2.0-70149116132&partnerID=MN8TOARS.
    10.1128/AEM.00845-09
  74. Monteiro, P.T.; Mendes, N.D.; Teixeira, M.C.; D'orey, S.; Tenreiro, S.; Mira, N.P.; Pais, H.; et al. "YEASTRACT-DISCOVERER: New tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae". Nucleic Acids Research 36 SUPPL. 1 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-38549135468&partnerID=MN8TOARS.
    10.1093/nar/gkm976
  75. Teixeira, M.C.; Dias, P.J.; Simões, T.; Sá-Correia, I.. "Yeast adaptation to mancozeb involves the up-regulation of FLR1 under the coordinate control of Yap1, Rpn4, Pdr3, and Yrr1". Biochemical and Biophysical Research Communications 367 2 (2008): 249-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-38349048493&partnerID=MN8TOARS.
    10.1016/j.bbrc.2007.12.056
  76. Vargas, R.C.; García-Salcedo, R.; Tenreiro, S.; Teixeira, M.C.; Fernandes, A.R.; Ramos, J.; Sá-Correia, I.. "Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells". Eukaryotic Cell 6 2 (2007): 134-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847188819&partnerID=MN8TOARS.
    10.1128/EC.00290-06
  77. Teixeira, M.C.; Duque, P.; Sá-Correia, I.. "Environmental genomics: mechanistic insights into toxicity of and resistance to the herbicide 2,4-D". Trends in Biotechnology 25 8 (2007): 363-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447291642&partnerID=MN8TOARS.
    10.1016/j.tibtech.2007.06.002
  78. Teixeira MC; Monteiro P; Jain P; Tenreiro S; Fernandes AR; Mira NP; Alenquer M; et al. "The YEASTRACT database: a tool for the analysis of transcription regulatory associations in Saccharomyces cerevisiae.". Nucleic acids research. 34 Database i (2006): http://europepmc.org/abstract/med/16381908.
    10.1093/nar/gkj013
  79. Teixeira, M.C.; Fernandes, A.R.; Mira, N.P.; Becker, J.D.; Sá-Correia, I.. "Early transcriptional response of Saccharomyces cerevisiae to stress imposed by the herbicide 2,4-dichlorophenoxyacetic acid". FEMS Yeast Research 6 2 (2006): 230-248. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645054024&partnerID=MN8TOARS.
    10.1111/j.1567-1364.2006.00041.x
  80. Tenreiro, S.; Vargas, R.C.; Teixeira, M.C.; Magnani, C.; Sá-Correia, I.. "The yeast multidrug transporter Qdr3 (Ybr043c): Localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin". Biochemical and Biophysical Research Communications 327 3 (2005): 952-959. http://www.scopus.com/inward/record.url?eid=2-s2.0-11844282218&partnerID=MN8TOARS.
    10.1016/j.bbrc.2004.12.097
  81. Viegas, C.A.; Cabral, M.G.; Teixeira, M.C.; Neumann, G.; Heipieper, H.J.; Sá-Correia, I.. "Yeast adaptation to 2,4-dichlorophenoxyacetic acid involves increased membrane fatty acid saturation degree and decreased OLE1 transcription". Biochemical and Biophysical Research Communications 330 1 (2005): 271-278. http://www.scopus.com/inward/record.url?eid=2-s2.0-15444379378&partnerID=MN8TOARS.
    10.1016/j.bbrc.2005.02.158
  82. Teixeira, M.C.; Santos, P.M.; Fernandes, A.R.; Sá-Correia, I.. "A proteome analysis of the yeast response to the herbicide 2,4-dichlorophenoxyacetic acid". Proteomics 5 7 (2005): 1889-1901. http://www.scopus.com/inward/record.url?eid=2-s2.0-18844392542&partnerID=MN8TOARS.
    10.1002/pmic.200401085
  83. Teixeira, M.C.; Telo, J.P.; Duarte, N.F.; Sá-Correia, I.. "The herbicide 2,4-dichlorophenoxyacetic acid induces the generation of free-radicals and associated oxidative stress responses in yeast". Biochemical and Biophysical Research Communications 324 3 (2004): 1101-1107. http://www.scopus.com/inward/record.url?eid=2-s2.0-5444271187&partnerID=MN8TOARS.
    10.1016/j.bbrc.2004.09.158
  84. Vargas, R.C.; Tenreiro, S.; Teixeira, M.C.; Fernandes, A.R.; Sá-Correia, I.. "Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): Localization and function as a quinidine resistance determinant". Antimicrobial Agents and Chemotherapy 48 7 (2004): 2531-2537. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042619287&partnerID=MN8TOARS.
    10.1128/AAC.48.7.2531-2537.2004
  85. Cabral, M.G.; Viegas, C.A.; Teixeira, M.C.; Sá-Correia, I.. "Toxicity of chlorinated phenoxyacetic acid herbicides in the experimental eukaryotic model Saccharomyces cerevisiae: Role of pH and of growth phase and size of the yeast cell population". Chemosphere 51 1 (2003): 47-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037400303&partnerID=MN8TOARS.
    10.1016/S0045-6535(02)00614-8
  86. Simões, T.; Teixeira, M.C.; Fernandes, A.R.; Sá-Correia, I.. "Adaptation of Saccharomyces cerevisiae to the herbicide 2,4-dichlorophenoxyacetic acid, mediated by Msn2p- and Msn4p-regulated genes: Important role of SPI1". Applied and Environmental Microbiology 69 7 (2003): 4019-4028. http://www.scopus.com/inward/record.url?eid=2-s2.0-17544401667&partnerID=MN8TOARS.
    10.1128/AEM.69.7.4019-4028.2003
  87. Cacho Teixeira, M.; Sá-Correia, I.. "Saccharomyces cerevisiae resistance to chlorinated phenoxyacetic acid herbicides involves Pdr1p-mediated transcriptional activation of TPO1 and PDR5 genes". Biochemical and Biophysical Research Communications 292 2 (2002): 530-537. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036298684&partnerID=MN8TOARS.
    10.1006/bbrc.2002.6691
  88. Tenreiro, S.; Nunes, P.A.; Viegas, C.A.; Neves, M.S.; Teixeira, M.C.; Cabral, M.; Sá-Correia, I.. "AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in saccharomyces cerevisiae". Biochemical and Biophysical Research Communications 292 3 (2002): 741-748. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036086750&partnerID=MN8TOARS.
    10.1006/bbrc.2002.6703
Journal issue
  1. Isabel Sá-Correia; Teixeira, Miguel Cacho; Duque, Paula; Ferreira. "Research Topic : "Physiological role and regulation of Multidrug/Multixenobiotic resistance membrane transporters" for Frontiers in Physiology - Membrane Physiology and Biophysics Section (Edited by Isabel Sá-Correia, M C Teixeira, P Duque, .7 articles); https://www.frontiersin.org/research-topics/1832/physiological-role-and-regulation-of-multidrugmultixenobiotic-resistance-membrane-transporters". (2014):
Magazine article
  1. Teixeira, Miguel Cacho; Cabrito, Tânia Rodrigues; Brazão, João; Isabel Sá-Correia. "Teixeira MC, Cabrito TR, Brazão J, Sá-Correia I. "Yeast as model eukaryote and expression host system: is it still useful?" Magazine SPM, 2013", Magazine SPM, 2013, http://www.spmicrobiologia.pt/.
  2. Teixeira, Miguel Cacho; Monteiro, P.; Jain, P.; Tenreiro, S.; Fernandes, A.R.; Mira, N.P.; Alenquer, M.; et al. "A Bioinformática e as Bases de Dados: o exemplo de uma Base de Dados para Análise de Mecanismos de Regulação em Levedura", Boletim da Biotecnologia, 2005, https://www.spbt.pt/#bulletins.
  3. Santos, P.M.; Teixeira, Miguel Cacho; Isabel Sá-Correia. "A Análise Proteómica Quantitativa na Revelação de Mecanismos de Resposta a stresse químico em microrganismos.", Boletim de Biotecnologia, 2004, https://www.spbt.pt/#bulletins.
Online resource
  1. Teixeira, Miguel Cacho; Monteiro, P.; Jain, P.; Tenreiro, S.; Fernandes, A.R.; Mira, N.P.; Alenquer, M.; Oliveira, A.L.; Isabel Sá-Correia. YEASTRACT database http://www.yeastract.com (regularly manually curated and updated to YEASTRACT+ http://yeastract-plus.org/ . Yeastract+ is described in the NAR Database Issue of 2020: https://doi.org/10.1093/nar/gkz859 ). 2006. http://www.yeastract.com, http://yeastract-plus.org/ , https://doi.org/10.1093/nar/gkz859.

Intellectual property

Patent
  1. Isabel Sá-Correia; Cabrito, T.R.; Teixeira, Miguel Cacho; Remy, E.; Duque, P.. 2013. "Utilização de um gene que confere resistência a xenobióticos em plantas". Portugal.
    Allowed

Other

Other output
  1. YEASTRACT+: a portal for the exploitation of global transcription regulation and metabolic model data in yeast biotechnology and pathogenesis. 2022. Miguel Teixeira; Marta Mota; Margarida Palma; Miguel Antunes; Pedro Pais; Isabel Sá-Correia; Claudine Chaouiya; et al. https://doi.org/10.1093/nar/gkac1041.
    10.1093/nar/gkac1041
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/07 Drug transporters in pathogenic yeast: in the crossroad between drug resistance and pathogenesis FEMS 2023
(Hamburg, Germany)
2023 Inward and outward drug transporters in pathogenic yeast SMYTE 2023
(Leuven, Belgium)
2022 Tackling the molecular basis of pathogenesis-related phenotypes in Candida species Seminar at the Université Libre de Bruxelles
ULB (Gosseliers, Belgium)
2021/09/17 Leveduras que causam infecções: a beleza dos vilões International Microorganism Day 2021
2021/07/01 Using Functional Genomics and Systems Biology to address antifungal drug resistance, drug targeting and drug design 2nd International Meeting Of The Portuguese Society Of Genetics – IMPSG 2021
2020/09/17 Databases in Microbiology: YEASTRACT International Microorganism Day 2020
2019/09/17 Os microrganismos que habitam no nosso corpo: um equilíbrio de forças International Microorganism Day’19
(Lisbon, Portugal)
2019/07/19 A palestra sobre Biologia que gostava de ter ouvido quando tinha 12 anos Academia de Versão IST
(Lisbon, Portugal)
2019/05/02 The YEASTRACT database Semana da Bioinformática
NCBI-AAIPS (Lisbon, Portugal)
2019/03/22 The Biodata.pt Research Infrastructure: the case study of the YEASTRACT+ information system V Semana da Bioengenharia
(Lisbon, Portugal)
2019/02/07 Candidiases: desafios terapêuticos e soluções possíveis DBE Open Labs Week
(Lisbon, Portugal)
2018/09/18 YEASTRACT+: a platform for the interspecies analysis of transcriptional regulation in yeasts of biotech and clinical relevance 2nd DD-DeCaF Workshop
(Oeiras, Portugal)
2018/06/14 Global transcriptional control of pathogenesis related phenotypes in Candida glabrata: using Functional Genomics and Systems Biology approaches XLII Jornadas Portuguesas de Genética
(Porto, Portugal)
2018/03/28 Deciphering antifungal drug resistance in Candida glabrata: new regulators and new effectors JSB2018 - The 91th annual meeting of Japanese Society for Bacteriology
Japanese Society for Bacteriology (Fukuoka, Japan)
2017/09/05 Pathoproteomics: unveiling new players in antifungal drug resistance in the human pathogen Candida glabrata 3rd International Symposium on Profiling
(Caparica, Portugal)
2017/07/04 Exploiting knowledge on the function of yeast multidrug transporters: from improved therapeutic approaches to cell factory optimization Ciência'17
(Lisbon, Portugal)
2017/04/03 Yeastract: predicting gene and genomic regulation in yeasts GREEKC COST-Action CA15205 Workshop 2017
(Msida, Malta)
2017/02/24 Antifungal drug resistance in the human pathogen Candida glabrata: new players unveiled by transcriptomics, proteomics and chemogenomics approaches II Fórum das Ciências Biológicas
(Lisbon, Portugal)
2016/12/16 The Yeastract database goes pathogenic Meeting of the iGenolevures network
(Paris, France)
2016/07/12 New mechanisms of resistance to azole antifungal drugs in Candida glabrata PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi
(Lisbon, Portugal)
2016/04/29 New mechanisms of antifungal drug resistance in C. glabrata, unveiled by iTRAQ-based membrane proteomics MiniSymposium on Fungal Biology
ITQB (Lisbon, Portugal)
2015/12/11 Using membrane-proteomics to unveil novel mechanisms of antifungal drug resistance in the pathogenic yeast Candida glabrata Microbiotec'15
(Lisbon, Portugal)
2015/10/10 MFS multidrug transporters in pathogenic fungi 7th Trends in Medical Mycology (TIMM-7)
(Lisbon, Portugal)
2014/03/07 S. cerevisiae strain optimization for first and second generation bioethanol production: a chemogenomics approach VI Jornadas de Genética e Biotecnologia
(Vila Real, Portugal)
2013/01/30 Unveiling antifungal drug resistance mechanisms in the human pathogen Candida glabrata: from gene to genome-wide approaches CBAA Seminars
Instituto Superior de Agronomia (Lisbon, Portugal)
2012/04/16 Antifungal drug resistance in yeasts: elucidation of the biomolecular mechanisms DBE Seminars
Instituto Superior Técnico (Lisbon, Portugal)
2011/12/02 Role and regulation of the Drug:H+ Antiporter family: from S. cerevisiae to C. glabrata Microbiotec'11
(Braga, Portugal)
2010/05/14 Toxicogenómica ambiental no organismo modelo Saccharomyces cerevisiae: extrapolação para eucariotas superiores II Jornadas de Genética e Biotecnologia
UTAD (Vila Real, Portugal)
2009/07/29 Identification of genome-wide determinants of yeast tolerance to ethanol and acetic acid for improved ethanol production National Meeting of Science 2009
(Lisbon, Portugal)
2006 A Bioinformática, as Bases de dados e o seu impacto na Biotecnologia: apresentação da YEASTRACT, a primeira base de dados em Biologia Molecular construída em Portugal Workshop Genoma: Desafio para a engenharia
(Coimbra, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022 - Current Elucidation of Natural Product Biosynthesis Capacities and Antifungal Activities in Marine Bacteria
Co-supervisor
 Biologia Molecular e Genética (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2023 - 2023 Genome-wide understanding of biofilm formation phenotypic variability in C. glabrata clinical isolates
Supervisor of Maria Olegovna Zolotareva
 Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019 - 2023 Genome-wide evolution towards pathogenesis in Candida glabrata
Supervisor of Mónica da Luz Galocha
 Biotecnologia e Biociências (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/15 - 2021/12/07 A Metabolic-Regulatory Genome-Scale Integration for Saccharomyces cerevisiae: Predicting Targets for Increased Ethanol Production
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/09/01 - 2021/11/11 Construction of a Metabolic Model for the Human Pathogen Candida parapsilosis and Early Identification of Putative Novel Anti-Fungal Drug Targets
Supervisor
 Microbiologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/09/01 - 2021/10/28 Construction of a global stoichiometric model for the human pathogen Candida auris: Aiming the identification of new drug targets
Supervisor
 Microbiologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09/01 - 2021/01/05 Role of the Candida glabrata mediator complex subunit Pgd1 in azole drug resistance and susceptibility: a transcriptomics approach
Supervisor
 Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2016/09/01 - 2020/10/15 Deciphering mechanisms of pathogenesis in Candida glabrata: in the crossroad between drug resistance and virulence
Supervisor
 Biotecnologia e Biociências (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09/25 - 2020/07/25 Studies on drug resistance and biofilm formation in Candida glabrata: focus on the implementation and optimization of CRISPR-Cas9 tools for C. glabrata genome editing
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/09/01 - 2019/09/27 Deciphering antifungal drug resistance mechanisms in the pathogenic yeast Candida glabrata: aiming the development of improved diagnosis and therapeutic approaches
Supervisor
 Biotechnology and Biosciences (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 - 2019 Identifying Pdr1-independent azole resistance mechanisms in Candida glabrata, based on directed evolution and genome sequencing
Supervisor
 Engenharia Farmacêutica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 - 2019 Genome-wide prediction of the regulatory mechanisms of probiotic activity in Saccharomyces boulardii
Supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 - 2019 Unveiling the complex regulatory network governing antifungal drug resistance in Candida glabrata: from new regulators to new effectors
Supervisor
 Biotecnologia e Biociências (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/09/01 - 2018/09/05 Studies on the role and regulation of the multidrug resistance efflux pumps Tpo1 and Pdr18 in yeast tolerance to ethanol and weak acid stresses, to increase yeast robustness
Co-supervisor
 Biotechnology and Biosciences (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Predicting the mechanisms of probiotic activity in Saccharomyces boulardii: contribution to the development of the ProBioYeastract database
Supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Construction and characterization of the L460A L434R mutant version of glucosamine-6-phosphate synthase from Candida albicans
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Biofilm formation by the human pathogen Candida glabrata: The regulator CgEfg2 and its targets
Supervisor
 Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Biofilm formation in Candida glabrata: the role of the Transcription Factor Tec1
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018 Driving microevolution towards azole resistance, independent from PDR1, in Candida glabrata
Supervisor
 Microbiologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2018 Role of the transcription factor Tog1 in C. glabrata virulence
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2018 Deciphering new regulators of drug resistance in pathogenic yeasts: the role of Rpn4 and Mrr1
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2018 Driving microevolution towards virulence and azole resistance in Candida glabrata
Supervisor
 Microbiologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2018 Biofilm formation by human pathogenic yeasts: the regulator CgTec1_2 and its targets
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2018 Biofilm formation by the human pathogen Candida glabrata: the regulator CgEfg2 and its targets
Supervisor
 Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2018 Response to flucytosine in Candida glabrata at the membrane proteome level: role of the DHA family and the transcription factor CgPdr1
Supervisor
 Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017 Genetic Transformation of Neochloris oleoabundans and Acutodesmus obliquus using bacterial conjugation
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2017 Integrated analysis of salt tolerance in Halomonas elongata from fermentation data
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2017 New players controlling multidrug resistance and biofilm formation in Candida glabrata: the important role of Rpn4
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2017 New players controlling multidrug resistance and biofilm formation in C. glabrata: the important role of Rpn4
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Developing quantitative mass spectrometry workflows for global identification and characterization of proteins
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Epigenetic drivers of genomic instability during neural differentiation
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Improvement of recombinant cellulase A production by Streptomyces lividans TK24: study on the effect of medium composition
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2016 Development of the PathoYeastract database: aiming the study of transcriptional regulation in pathogenic yeasts
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2016 Functional analysis of the Candida glabrata drug:H+ antiporters Dtr1 and Tpo4: role in stress resistance and virulence
Supervisor
 Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2015 - 2015 Role of the Candida glabrata drug:H+ antiporters in biofilm formation and virulence: emphasis on CgDtr1, CgQdr2, CgTpo1_2 and CgTpo4
Supervisor
 Microbiologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Unveiling the mechanisms of evolution towards fluconazole resistance of a Candida glabrata clinical isolate: a transcriptomics approach
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Computational Prediction and Analysis of CRISPR-Cas Systems in Chinese Human Gut Metagenomic Samples
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2015 Unveiling the mechanisms of evolution towards fluconazole resistance of a Candida glabrata clinical isolate
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2015 Role and regulation of multidrug transporters in Candida glabrata virulence and antifungal drug resistance
Supervisor
 Microbiologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2009/09/01 - 2014/02/01 Multidrug resistance in Candida glabrata: systematic analysis of the role and regulation of the poorly characterized DHA1 transporters using gene and genome-wide approaches
Supervisor
 Biotechnology and Biosciences (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2014 Membrane proteome-wide response to the antifungal drug clotrimazole in Candida glabrata: role of the transcription factor CgPdr1 and the Drug:H+ Antiporters CgTpo1_1 and CgTpo1_2
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2014 Helping cells jump to conclusions. Design and implementation of a biological circuit capable of responding to pre-equilibrium information
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2014 Response to clotrimazole in Candida glabrata at the membrane proteome level: role of the DHA family and the transcription factor CgPdr1
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Profiling antifungal drug resistance in a collection of Candida glabrata clinical isolates: correlation with the expression of multidrug efflux pumps
Supervisor
 Ciências de Engenharia - Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Contribution to the functional analysis of the paralogous gene-pairs CgTpo1_1 and CgTpo1_2 and CgFlr1_1 and CgFlr1_2 from the human pathogen Candida glabrata
Supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Profiling antifungal drug resistance in a collection of Candida glabrata clinical isolates: correlation with the expression of multidrug efflux pumps
Supervisor
 Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Genome-wide identification of the determinants of resistance or susceptibility to the antifungal drug 5-flucytosine: role of cell envelope related proteins
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 - 2013 Genome-wide identification of mechanisms of resistance to the antifungal drug flucytosine: from S. cerevisiae to C. glabrata
Supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 - 2012 Contribution to the functional analysis of the paralogous gene-pairs CgTpo1_1 and CgTpo1_2 and CgFlr1_1 and CgFlr1_2 from the human pathogen Candida glabrata
Supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 - 2012 Role of the multidrug efflux pumps CgAqr1 and CgTpo2/3 in Candida glabrata resistance to flucytosine and azole drugs
Supervisor
 Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 - 2012 Role of the multidrug efflux pumps CgAqr1 and CgTpo2/3 in Candida glabrata resistance to flucytosine and azole drugs
Supervisor
 Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 - 2011 Functional analysis of the uncharacterized Candida glabrata drug:H+ antiporters CgAqr1 (ORF CAGL0J09944g) and CgTpo2/3 (ORF CAGL0I10384g): role in antifungal drug resistance
Supervisor
 Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2007 - 2011 Caracterização de novos transportadores de múltiplas drogas e das complexas redes de regulação genética envolvidas na aquisição de resistência a drogas e outros stresses químicos em levedura
Co-supervisor
 Biotecnologia (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2007 - 2007 Functional analysis of Saccharomyces cerevisiae and Arabidopsis thaliana multidrug resistance transporters involved in the resistance to the herbicide 2,4-D
Co-supervisor
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2007 - 2007 Análise global dos mecanismos de resistência da levedura ao stresse induzido por concentrações elevadas de etanol e glucose
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2016/07/11 - 2016/07/14 PYFF6 – 6th Conference on Physiology of Yeast and Filamentous Fungi (2016/07/11 - 2016/07/14)
Conference (Member of the Organising Committee)
2016/02/15 - 2016/06/30 DBE 2016 Spring Seminar Cycle – a set of six biweekly seminars of subjects related to Bioengineering developments and applications, open to the public, IST. (2016/02/15 - 2016/06/30)
Other (Co-organisor)
2015/09/01 - 2015/12/16 DBE 2015 Autumn Seminar Cycle – a set of six biweekly seminars of subjects related to Bioengineering developments and applications, open to the public, IST. (2015/09/01 - 2015/12/16)
Other (Co-organisor)
2015/01/04 - 2015/01/09 Winter School in Systems Biology” – a week-long intensive course offered, within the scope of the ERASMUS-MUNDUS MSc in Systems Biology, to post-graduate european students, Jan 2015. (2015/01/04 - 2015/01/09)
Workshop (Co-organisor)
2014/07/10 - 2014/07/11 XX Jornadas de Biologia de Leveduras Professor Nicolau Van Uden (2014/07/10 - 2014/07/11)
Conference (Member of the Organising Committee)
2014/01/07 - 2014/01/12 “Winter School in Systems Biology” – a week-long intensive course offered, within the scope of the ERASMUS-MUNDUS MSc in Systems Biology, to post-graduate european students, Jan 2014 (2014/01/07 - 2014/01/12)
Workshop (Co-organisor)
2013/01/05 - 2013/01/10 “Winter School in Systems Biology” – a week-long intensive course offered, within the scope of the ERASMUS-MUNDUS MSc in Systems Biology, to post-graduate european students, Jan 2013 (2013/01/05 - 2013/01/10)
Workshop (Co-organisor)
2012/01/06 - 2012/01/12 “Winter School in Systems Biology” – a week-long intensive course offered, within the scope of the ERASMUS-MUNDUS MSc in Systems Biology, to post-graduate european students, Jan 2012. (2012/01/06 - 2012/01/12)
Workshop (Co-organisor)
2011/01/03 - 2011/01/18 “Winter School in Systems Biology” – a two week-long intensive course offered, within the scope of the ERASMUS-MUNDUS MSc in Systems Biology, to post-graduate european students, Jan 2011. (2011/01/03 - 2011/01/18)
Workshop (Co-organisor)
2007/11/30 - 2007/12/02 II Congresso MICRO’07 BIOTEC’07 – XXXIII Jornadas Portuguesas de Genética (2007/11/30 - 2007/12/02)
Conference (Member of the Organising Committee)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/07/31 Blueprint: Documenting the complexity of metabolic regulation by reconstruction of integrated metabolic-regulatory models
(Thesis) Main arguer
 Fernando Pereira Cruz (PhD)
Universidade do Minho, Portugal
2023 Unveiling the antifungal resistance mechanisms of the emergent fungal pathogen Candida parapsilosis
(Thesis) Main arguer
 Joana Alexandra Vilarinho Branco (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2023 Secondary metabolite biosynthesis by Aquimarina species: emerging properties and bioactivities from the rare marine biosphere
(Thesis) Arguer
 Sandra Cristina Godinho Pires da Silva (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/01/12 Exploring the synergy between copper and antifungals
(Thesis) Arguer
 Ana Carolina Gaspar Cordeiro (PhD)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022 Deepening the role of CgHaa1- and CgPdr1- pathways in stress resilience and pathogenesis of Candida glabrata to foster new antifungal treatments
(Thesis) Arguer
 Sara Barbosa Salazar (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022 Astrobiology analysis of icy biomes as a proxy for extra-terrestrial life in icy worlds
(Thesis) Arguer
 Lígia Patrícia Fonseca Coelho (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022 Amino acid excretion by yeast: transport mechanisms and physiological role
(Thesis) Main arguer
 George Kapetanakis (PhD)
Université Libre Bruxelles Faculté des Sciences, Belgium
2022 Utilizing ionic liquids as a versatile tool to study antimicrobial strategies of and against filamentous fungi
(Thesis) Main arguer
 Maika Clara Rothkegel (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/05/18 Valorisation of pectin-rich agro-industrial residues by yeasts: Potential and Challenges
(Thesis) Main arguer
 Luís Miguel Candeias Martins (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/04/01 Synthetic biology approaches to foster yeasts as hosts for the production of carboxylic acids and their derivatives: emphasis on levulinic and itaconic acids
(Thesis) Arguer
 Ana Isabel de Vila-Santa Braga Campos, (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/05/01 Function and Regulation of Candida albicans and C. glabrata Carboxylic Acid Transporters and their Role in Biofilm Formation, Antifungal Drug Resistance and Phagocytosis
(Thesis) Main arguer
 2 Rosana Maria Abreu Alves (PhD)
Universidade do Minho, Portugal
2020/04/15 Production of first- and second- generation bioethanol by yeasts: global warming potential and fermentation productivity issues
(Thesis) Main arguer
 Rui Cruz Pacheco (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/12/22 Tracking the genes and pathways involved in Saccharomyces cerevisiae response and tolerance to the wine preservatives SO2 and chitosan: from molecular analysis to OMICS approaches
(Thesis) Main arguer
 Patrícia Pinheiro Lage (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2019 Candida species vaginal virulence determinants: role of environmental factors
(Thesis) Main arguer
 Bruna Fernandes Gonçalves (PhD)
Universidade do Minho, Portugal
2019 Designing synthetic Ashbya cell factories
(Thesis) Main arguer
 Rui Miguel Correia da Silva (PhD)
Universidade do Minho, Portugal
2018 Accelerating metabolic engineering tasks by the in silico development of yeast cell factories
(Thesis) Main arguer
 Hélder Moisés Gonçalves Pinheiro Lopes (PhD)
Universidade do Minho, Portugal
2017 Unravelling genes, the Haa1-signalling pathway and cell envelope properties responsible for the remarkable high acetic acid tolerance of Zygosaccharomyces bailii
(Thesis) Arguer
 Filipa da Canaveira Roque Baker (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Stress response mechanisms underlying metal detoxification
(Thesis) Main arguer
 Soraia C. Marques Caetano (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017 Towards the improvement of tolerance to acetic and formic acids in yeasts: identification of applicant genes and engineering of the Haa1 transcription factor
(Thesis) Arguer
 Sílvia Catarina Filipe Henriques (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 Triggering secondary metabolite biosynthesis: exploring the effects of ionic liquids in fungal metabolism
(Thesis) Main arguer
 Paula Cristina de Azevedo Alves Marques (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 Mechanistic insights into adaptation and tolerance to acetic acid in Saccharomyces cerevisiae and Zygosaccharomyces bailii
(Thesis) Arguer
 Joana Filipa Fernandes Guerreiro (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 Yeast response to arsenic's threats
(Thesis) Main arguer
 Ana Rita Tomé Ferreira (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 ASYN and Tau interaction: new drug target for neurodegenerative diseases
(Thesis) Main arguer
 Gianmario Ciaccioli (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 Listeria monocytogenes interstrain comparative exoproteome analyses at different temperatures
(Thesis) Main arguer
 Paula Cristina Branco Cabrita Cunha (PhD)
Universidade de Lisboa Instituto Superior de Agronomia, Portugal
2014 Pheno-metabolomics: integrative bioinformatics for yeast molecular biotechnology
(Thesis) Main arguer
 Ricardo Filipe Azevedo Franco Duarte (PhD)
Universidade do Minho, Portugal
2013 Engineering of core pentose metabolism in Saccharomyces cerevisiae for bio-ethanol production
(Thesis) Main arguer
 Filipa Alexandra Barroso Pereira (PhD)
Universidade do Minho, Portugal
2013 Understanding the biotechnological potential of Ashbya gossypii
(Thesis) Main arguer
 Tatiana Sofia da Quinta Vidal Aguiar (PhD)
Universidade do Minho, Portugal
2013 Phytoremediation of soils contaminated with organic polutants
(Thesis) Main arguer
 Renata Alexandra Alves Gomes Ferreira (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 Reconstruction of the genome-scale metabolic network of Kluyveromyces lactis
(Thesis) Main arguer
 Oscar Manuel Lima Dias (PhD)
Universidade do Minho, Portugal
2012 Genome wide expression approaches applied to biomedical research: long-term adaptation Burkholderia cenocepacia to cystic fibroses patient's airways and extended ex-vivo cultivation of human mesenchymal stem cells
(Thesis) Arguer
 Andreia Madeira (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 Yeast responses and determinants of resistance to propionic acid or ethanol at a systems level: chemogenomic and metabolomic strategies
(Thesis) Arguer
 Artur Bastos Lourenço (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 Sugar transport in yeast: phylogenetic analysis of sugar porters and involvement in the global response to chemical stress
(Thesis) Arguer
 Margarida Palma (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010 Yeast toxicogenomics focused on the agricultural fungicide mancozeb: involvement of the drug: H+ antiporter Flr1p
(Thesis) Main arguer
 Paulo Jorge Moura Pinto da Costa Dias (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 Yeast as a model in pharmacogenomics: targets and mechanisms of resistance to imatinib and quinine
(Thesis) Arguer
 Sandra Sofia Costa dos Santos (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 Role of Yap8 and Yap1 b-ZIP transcription factors in arsenic stress
(Thesis) Main arguer
 Catarina Sá Almeida Amaral (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2008 Adaptation and resistance to weak acid food preservatives in Saccharomyces cerevisiae: the Haa1p- and Rim101p-signalling pathways
(Thesis) Arguer
 Nuno Gonçalo Pereira Mira (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Conference scientific committee

Conference name Conference host
2023/12/07 - 2023/12/09 Microbiotec 2023
2023/07/09 - 2023/07/13 FEMS 2023
2021/11/23 - 2021/11/26 Microbiotec 2021 UNL
2019/12/05 - 2019/12/07 Microbiotec 2019
2017/12/07 - 2017/12/09 Microbiotec 2017
2017/02/16 - 2017/02/18 ENBENG 2017, the IEEE 5th Portuguese Meeting on Bioengineering

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2016/09/01 - Current Functional Genomics and Bioinformatics (as coordinator) Engenharia Biológica (Mestrado integrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/09/01 - Current Biological Sciences Lab (as coordinator) Biotecnologia (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/09/01 - Current Functional and Comparative Genomics (as coordinator) Biotecnologia (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2008/09/01 - Current Molecular and Cellular Microbiology Microbiologia (Mestrado integrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/11/15 - 2023/11/19 Microbial Multiomics - a week-long intensive course offered, within the scope of the ATHENS programme, with the support of the European Communities SOCRATES Programme, to undergraduate and post-graduate european students, Nov 2023.
2022/11/12 - 2022/11/17 Microbial Multiomics - a week-long intensive course offered, within the scope of the ATHENS programme, with the support of the European Communities SOCRATES Programme, to undergraduate and post-graduate european students, Nov 2022.
2021/11/15 - 2021/11/19 Microbial Multiomics¿ ¿ a week-long intensive course offered, within the scope of the ATHENS programme, with the support of the European Communities SOCRATES Programme, to undergraduate and post-graduate european students, Nov 2021. Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/11/15 - 2019/11/20 “Microbial Multiomics” – a week-long intensive course offered, within the scope of the ATHENS programme, with the support of the European Communities SOCRATES Programme, to undergraduate and post-graduate european students, Nov 2019. Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/04/10 - 2019/04/15 “Microbial Multiomics” – a week-long intensive course offered, within the scope of the ATHENS programme, with the support of the European Communities SOCRATES Programme, to undergraduate and post-graduate european students, Apr 2019. Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/11/01 - 2018/11/05 “Microbial Multiomics” – a week-long intensive course offered, within the scope of the ATHENS programme, with the support of the European Communities SOCRATES Programme, to undergraduate and post-graduate european students, Nov 2018. Universidade de Lisboa Instituto Superior Técnico, Portugal
2009/09/01 - 2011/01/31 Biotechnology Laboratories I (as coordinator) Biotecnologia (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2023 - Current External project reviewer for the BBSRC - Biotechnology and Biological Sciences Research Council, Uk
Evaluator
2020 - Current External project reviewer for the National Research, Development and Innovation Office
Evaluator
 Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, Hungary
2019 - Current External project reviewer for the Welcome Trust, UK
Evaluator
 Wellcome Trust, United Kingdom
2018 - Current External project reviewer for FWO - The Research Foundation – Flanders, Belgium
Evaluator
 Fonds Wetenschappelijk Onderzoek Vlaanderen, Belgium
2017 - Current External project reviewer for the FWF Austrian Science Fund, Austria
Evaluator
 Fonds zur Förderung der wissenschaftlichen Forschung, Austria
2017 - Current External project reviewer for the FINOVI Foundation, Lyon, France
Evaluator
 Fondation Innovations en Infectiologie, France
2015 - Current External project reviewer for the Medical Research Council, UK
Evaluator
 Medical Research Council, United Kingdom
2013 - Current External project reviewer for L'Agence Nationale de la Recherce, France
Evaluator
 Agence nationale de la recherche, France
2017 - 2017 External project reviewer for ERC Advanced Grants
Evaluator
 European Research Council, Belgium
2016 - 2017 External project reviewer for the National Science Centre, Poland
Evaluator
 Narodowe Centrum Nauki, Poland

Journal scientific committee

Journal title (ISSN) Publisher
2020/01/01 - Current FEMS Yeast Research (1567-1364) Oxford University Press
2019/01/01 - Current Frontiers in Bioengineering and Biotechnology
2018 - Current Genes (2073-4425) MDPI AG
2018 - Current Applied and Environmental Microbiology (1098-5336) American Society for Microbiology
2018 - Current Microbial Cell (2311-2638) Shared Science Publishers OG
2018 - Current Frontiers in Cellular and Infection Microbiology (2235-2988) Frontiers Media SA
2016 - Current Frontiers in Microbiology (1664-302X) Frontiers Media SA
2016 - Current Frontiers in Medicine (2296-858X) Frontiers Media SA
2016 - Current Frontiers in Public Health (2296-2565) Frontiers Media SA
Distinctions

Award

2023 Researcher award Universidade de Lisboa/Caixa Geral de Depósitos, in the field of Biology, Biological Engineering, Biochemistry and Biotechnology (honorable mention)
Universidade de Lisboa, Portugal
2022 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021 Researcher award Universidade de Lisboa/Caixa Geral de Depósitos, in the field of Biology, Biological Engineering, Biochemistry and Biotechnology (honorable mention)
Universidade de Lisboa, Portugal
2020 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 Researcher award Universidade Técnica de Lisboa/Santander (honorable mention)
2012 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 Researcher award Universidade Técnica de Lisboa/Santander (honorable mention)
2011 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 Diploma de Excelência Pedagógica
Universidade de Lisboa Instituto Superior Técnico, Portugal
2009 Young Researcher in Microbiology award Portuguese Society for Microbiology/Alfagene
2008 Young Researcher award UTL/Deloitte, in the field of Biochemistry and Biotechnology
2007 Sartorius award - Innovation in Microbiology/Biotechnology