???global.info.a_carregar???
Identification

Personal identification

Full name
Mariana Filipa Simões Diniz

Citation names

  • Diniz, Mariana S.

Author identifiers

Ciência ID
CA17-4072-0E89
ORCID iD
0000-0002-2161-9676

Email addresses

  • mdiniz@cnc.uc.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Elementary (A2) Elementary (A2) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2023/01 - 2027/01
Ongoing
 Experimental Biology and Biomedicine (Doutoramento)
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2022/06 - 2022/06
Concluded
 Essentials of Grant Proposal Development (Outros)
Collaborative Institutional Training Initiative , United States
2022/05/26 - 2022/05/27
Concluded
 Human Research - Biomedical Investigators (Outros)
Major in Completed modules include: Informed Consent (ID:3); Genetic Research in Human Populations (ID:6); Research Involving Children (ID:9); Research Involving Pregnant Women, Fetuses, and Neonates (ID:10); Stem Cell Research Oversight (Part I) (ID:13882)
Collaborative Institutional Training Initiative , United States
2022/02 - 2022/02
Concluded
 R Programming Introduction Course (Outros)
Medizinische Universität Graz, Austria
2019/09 - 2021/11/29
Concluded
 Bioquímica (Mestrado)
Universidade de Coimbra, Portugal
"Made in the Womb: Maternal Programming of Offspring Cardiovascular Function" (THESIS/DISSERTATION)
 18
2016/09/19 - 2019/06/28
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra, Portugal
""Measurement of Respiratory Chain Enzyme Activities in Sheep Liver Homogenates"." (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2024/01 - Current Visiting Researcher (Research) Medizinische Universität Graz, Austria
Medizinische Universität Graz, Austria
2023 - Current Researcher (Research) Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2022/05/23 - 2022/12 Researcher (Research) Atrium Health Wake Forest Baptist Medical Center, United States
Atrium Health Wake Forest Baptist Medical Center, United States
2022/01 - 2022/03 Research Trainee (Research) Medizinische Universität Graz, Austria
Medizinische Universität Graz, Austria
2020/08 - 2021/10 Researcher (Research) Universidade de Coimbra, Portugal
Universidade de Coimbra, Portugal
2020/01 - 2020/01 Research Trainee (Research) Universidade de Coimbra, Portugal
Universidade de Coimbra, Portugal

Others

Category
Host institution 		Employer
2019/02 - 2019/07 Research Trainee (Research) Universidade de Coimbra, Portugal
Projects

Grant

Designation Funders
2022 - Current 'BraveHEART: Improvig Nature by Addressing Bioactive Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications in Non-Alcoholic Fatty Liver Disease'
EXPL/BIA-BQM/1361/2021
Master Student Fellow
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Outputs

Publications

Conference abstract
  1. Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena S. "Maternal physical exercise during obesogenic pregnancy modulates cardiac nitric oxide signaling in young-adult offspring". 2023.
    https://doi.org/10.1111/eci.13992
  2. Carolina Tocantins, João D. Martins, Luís F. Grilo, Mariana S. Diniz, Óscar M. Rodrigues, Lina Carvalho, Jelena Stevanov. "Modulação do metabolismo cardíaco materno pela prática de exercício físico durante a gravidez com diabetes gestacional". 2023.
  3. Luís F. Grilo, Carolina Tocantins, Mariana S. Diniz, João D. Martins, Débora Mena, Ricardo Amorim, Jelena Stevanovic-Sil. "Modulação da comunicação endócrina fígado--tecido adiposo e do estado redox ao longo do envelhecimento da descendência pela prática de exercício materno durante uma gestação obesogénica". 2023.
  4. Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena S. "Exercício físico durante gestação obesogénica induz adaptações mitocondriais cardíacas em descendentes que prevalecem até à idade adulta". 2023.
  5. Xiaoxian Zhao, Chad McCall, Jared Block, Sarah Ondrejka, Beenu Thakral, Sa Wang, Yahya Al-Ghamdi, Wayne Tam, Brittany Co; Mariana S. Diniz, Feng Lin, Eric Hsi. "CD6 is Expressed in Aggressive NK-Cell Leukemia (ANKL) and Extranodal NK/T-Cell Lymphoma (ENKTL) and Is a Potential Therapeutic Target". 2023.
    https://doi.org/10.1016/j.labinv.2023.100106
  6. Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena S. "Adaptative Capacity of Young-Adult Offspring's Cardiac Mitochondrial Biogenesis and Dynamics to Maternal Physical Exercise Practice During an Obesogenic Pregnancy". Paper presented in 17th edition of PDBEB symposium: Science Challenges: This Fight of Ours, 7th and 8th February 2023, Coimbra, Portugal, 2023.
  7. Susana P. Pereira, Mariana S. Diniz, João D. Martins, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo et. al. "Physical exercise during obesogenic pregnancy modulates young-adult offspring's cardiac mitochondrial function in a sex-specific fashion". 2022.
    10.1111/eci.13796
  8. Luís F. Grilo, Carolina Tocantins, Mariana S. Diniz, João D. Martins, Jelena Stevanovic-Silva, Jorge Beleza, et. al. "Impact of gestational exercise during maternal obesity in the offspring metabolic-endocrine environment: role of aging". Paper presented in 56th Meeting of European Society for Clinical Investigation, Bari, 2022.
  9. Carolina Tocantins, Óscar M. Rodrigues, João D. Martins, Luís F. Grilo, Mariana S. Diniz, et.al. "Detraining of the heart: impact of exercise practice exclusively during gestational diabetes mellitus on maternal cardiac mitochondria". Paper presented in 56th Meeting of European Society for Clinical Investigation, 2022.
  10. Susana P. Pereira; Diniz, Mariana S.; Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; et. al. "Beating cardiovascular disease: Physical exercise performed during obesogenic pregnancy to improve offspring mitochondrial cardiac function". Paper presented in 55th Annual Scientific Meeting - The Micro Me’s – Exploring Microbiotica in Health and Disease, 2021.
    10.1111/eci.13567
  11. Luís F. Grilo; Ivan Viegas; Diniz, Mariana S.; Carolina Tocantins; João D. Martins; Stephen Ford; Peter W. Nathanielsz; Paulo J. Oliveira; Susana P. Pereira. "Maternal obesity (MO) during pregnancy induces maternal liver damage andcompromises fetal hepatic function". Paper presented in 55th Annual Scientific Meeting of the European Society for Clinical Investigation, 2021.
  12. Susana P. Pereira; Diniz, Mariana S.; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Grilo, Luís F.; et. al.. "Maternal physical exercise during obesogenic pregnancy to protect the offspring cardiac mitochondrial function". Paper presented in Nature Conferences: Metabolism in Health and Disease, 2021.
  13. Susana P. Pereira; Mariana S. Diniz; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Grilo, Luís F.. "Could maternal obesity during gestation induce mitochondrial bioenergetic alterations in the offspring heart?". Paper presented in Olimpíadas Universitárias da Bioquímica – Edição Especial COVID-19, 2021.
  14. Diniz, Mariana S.; Susana P. Pereira; Tocantins, Carolina; Óscar M. Rodrigues; João D. Martins; Grilo, Luís F.; et. al. "Poderá a Obesidade Materna Alterar a Bioenergética Mitocondrial Cardíaca dos Descendentes?". Paper presented in 17.º Congresso Português de Diabetes, Virtual Meeting, 2021.
    Published
  15. Luís F. Grilo; Mariana S. Diniz; Carolina Tocantins; João D. Martins; Inês Baldeiras; Stephen Ford; Peter W. Nathanielsz; Paulo J. Oliveira; Susana P. Pereira. "Obesidade Gestacional Induz Stress e Dano Oxidativo Hepático Promovendo Macroautofagia No Fígado Materno". Paper presented in 16.º Congresso Português de Diabetes, 2021.
    Published
  16. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Mariana S. Diniz; et. al. "The effects of exercise during gestational diabetes mellitus on maternal cardiac metabolic function". Paper presented in Olimpíadas Universitárias da Bioquímica – Edição Especial COVID-19, 2021.
  17. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Mariana S. Diniz; et. al. "Prática de Exercício Físico Durante Diabetes Gestacional como Estratégia para a Modulação da Função Cardíaca da Gestante". Paper presented in 17.º Congresso Português de Diabetes, Virtual Meeting, 2021.
    Published
  18. Grilo, Luís F.; Carolina Tocantins; Diniz, Mariana S.; João D. Martins; Stephen Ford; Peter W. Nathanielsz; Paulo J. Oliveira; Susana P. Pereira. "Obesidade Gestacional Causa Stress Oxidativo e Dano Mitocondrial Fetal Hepático Com Maior Impacto No Lóbulo Direito Do Fígado". Paper presented in 17.º Congresso Português de Diabetes, Virtual Meeting, 2021.
  19. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Mariana S. Diniz; Jelena Stevanovic-Silva; Jorge. "The effects of exercise during gestational diabetes mellitus on maternal cardiac metabolic function". Paper presented in Olimpíadas Universitárias da Bioquímica, 2021.
  20. Grilo, Luís F.; Martins, João D.; Diniz, Mariana S.; Carolina Tocantins; Chiara H. Cavallaro; Inês Baldeiras; Teresa Cunha-Oliveira; et al. "Maternal Obesity During Pregnancy Induces Oxidative Stress and Mitochondria Functional Alterations in Sheep Maternal Liver". Paper presented in 68th Annual Meeting of the Society for Reproductive Investigation, 2021.
    https://doi.org/10.1007/s43032-021-00654-8
  21. Susana P. Pereira; Grilo, Luís F.; Diniz, Mariana S.; Carolina Tocantins; João Martins; Stephen Ford; Peter W. Nathanielsz; Paulo J. Oliveira. "Maternal obesity induces fetal hepatic oxidative stress (OS) and mitochondrial damage predominantly in the right lobe". Paper presented in 68th Annual Meeting of the Society for Reproductive Investigation (SRI), 2021.
  22. Grilo, Luís F.; João D. Martins; Mariana S. Diniz; Carolina Tocantins; Chiara H. Cavallaro; Inês Baldeiras; Teresa Cunha-Oliveira; et. al. "Maternal Obesity During Pregnancy Induces Oxidative Stress and Mitochondria Functional Alterations in Sheep Maternal Liver". Paper presented in 68th Annual Meeting of theSociety for Reproductive Investigation, 2021.
  23. Susana P. Pereira; Diniz, Mariana S.; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Grilo, Luís F.; et. al.. "Maternal physical exercise during obesogenic pregnancy to protect the offspring cardiac mitochondrial function". Paper presented in Nature Conferences: Metabolism in Health and Disease, 2021.
  24. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Grilo, Luís F.; Diniz, Mariana S.; et. al.. "Maternal cardiac mitochondrial alterations induced by gestational diabetes mellitus prevail at 8 weeks postpartum". Paper presented in 1st Virtual Meeting of the Society for Heart and Vascular Metabolism, 2021.
  25. Susana P. Pereira; Diniz, Mariana S.; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Grilo, Luís F.; et. al.. "Preventing cardiac disease: maternal gestational exercise to mitigate obesity-induced cardiac metabolic impairment in the offspring". Paper presented in Society for Heart and Vascular Metabolism, 2021.
  26. Diniz, Mariana S.; Grilo, Luís F.; João D. Martins; Stephen Ford; Peter W. Nathanielsz; Oliveira, Paulo J.; Susana P. Pereira. "Maternal obesity (MO) during pregnancy: are there implications for maternal hepatic mitochondrial activity?". Paper presented in ESCI Virtual Meeting 2020, 2020.
    10.1111/eci.13369
Conference poster
  1. Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena S. "Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling". Paper presented in Mitochondria in Aging, Cancer and Cell Death (MAC 2023), 30th November – 2nd December 2023, Coimbra, Portugal, 2023.
  2. Carolina Tocantins, João D. Martins, Luís F. Grilo, Mariana S. Diniz, Óscar M. Rodrigues, Lina Carvalho, Jelena Stevanov. "The long-term cardiovascular consequences of short-term exercise cessation after gestational diabetes for the maternal heart.". Paper presented in 57th Annual Scientific Meeting of the European Society for Clinical Investigation, 7-9th June 2023, Prague, Czech Republic, 2023.
  3. Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena S. "Maternal physical exercise during obesogenic pregnancy modulates cardiac nitric oxide signaling in young-adult offspring". Paper presented in 57th Annual Scientific Meeting of the European Society for Clinical Investigation, 7-9th June 2023, Prague, Czech Republic, 2023.
  4. Carolina Tocantins, João D. Martins, Luís F. Grilo, Mariana S. Diniz, Óscar M. Rodrigues, Lina Carvalho, Jelena Stevanov. "High-fat high-sugar diet and short-term training cessation: Implications for mitochondrial adaptations in the female heart.". Paper presented in Mitochondrial physiology, redox biology, and genetics (MitoPorto) 2023. 12th and 13th May 2023, Porto, Portugal, 2023.
  5. Luís F. Grilo, Mariana S. Diniz, Carolina Tocantins, João D. Martins, Débora Mena, Jelena Stevanovic-Silva, Jorge Beleza. "The effects of physiologic aging on liver, adipose tissue and their crosstalk: sex-specific oxidative stress and endocrine alterations in rats". Paper presented in Mitochondrial physiology, redox biology, and genetics (MitoPorto) 2023. 12th and 13th May 2023, Porto, Portugal., 2023.
  6. Carolina Tocantins, João D. Martins, Luís F. Grilo, Mariana S. Diniz, Óscar M. Rodrigues, Lina Carvalho, Jelena Stevanov. "Modulação do metabolismo cardíaco materno pela prática de exercício físico durante a gravidez com diabetes gestacional.". Paper presented in 19.º Congresso Português de Diabetes, 2023.
  7. Luís F. Grilo, Carolina Tocantins, Mariana S. Diniz, João D. Martins, Débora Mena, Ricardo Amorim, Jelena Stevanovic-Sil. "Modulação da comunicação endócrina fígado--tecido adiposo e do estado redox ao longo do envelhecimento da descendência pela prática de exercício materno durante uma gestação obesogénica.". Paper presented in 19.º Congresso Português de Diabetes, 2023.
  8. Mariana S. Diniz*, Susana P. Pereira*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena S. "Exercício físico durante gestação obesogénica induz adaptações mitocondriais cardíacas em descendentes que prevalecem até à idade adulta". Paper presented in 19.º Congresso Português de Diabetes, 2023.
  9. Xiaoxian Zhao, Chad McCall, Jared Block, Sarah Ondrejka, Beenu Thakral, Sa Wang, Yahya Al-Ghamdi, Wayne Tam, Brittany Co; Mariana S. Diniz, Feng Lin, Eric Hsi. "CD6 is Expressed in Aggressive NK-Cell Leukemia (ANKL) and Extranodal NK/T-Cell Lymphoma (ENKTL) and Is a Potential Therapeutic Target.". Paper presented in USCAP 112th Annual Meeting, 2023.
  10. Carolina Tocantins, Óscar M. Rodrigues, João D. Martins, Luís F. Grilo, Mariana S. Diniz, Jelena Stevanovic-Silva, Jorge. "Gestational diabetes mellitus: challenging the maternal heart beyond pregnancy". Paper presented in . 117th edition of PDBEB symposium: Science Challenges: This Fight of Ours, 7th and 8th February 2023, Coimbra, Portugal, 2023.
  11. Susana P. Pereira; Mariana S. Diniz; João D. Martins.; Óscar M. Rodrigues; Tocantins, Carolina; Luís F. Grilo.; Jelena S. "Physical exercise during obesogenic pregnancy modulates young-adult offspring's cardiac mitochondrial function in a sex-specific fashion". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation, 2022.
  12. Susana P. Pereira; Diniz, Mariana S.; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Grilo, Luís F.; et. al. "Maternal physical exercise during obesogenic pregnancy to protect the offspring cardiac mitochondrial function". Paper presented in Nature Conferences: Metabolism in Health and Disease, 2021.
  13. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Grilo, Luís F.; Diniz, Mariana S.; et. al. "Maternal cardiac mitochondrial alterations induced by gestational diabetes mellitus prevail at 8 weeks postpartum". Paper presented in Society for Heart and Vascular Metabolism 2021: Metabolism at the crossroads of health and disease, 2021.
  14. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Mariana S. Diniz; Jelena Stevanovic-Silva; Jorge. "The metabolic challenge of pregnancy: A toll on the maternal heart aggravated by Gestational Diabetes Mellitus". Paper presented in 55th Annual Scientific Meeting of the European Society for Clinical Investigation, 2021.
  15. Susana P. Pereira; Mariana S. Diniz; Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Jelena Stev. "Beating cardiovascular disease: Physical exercise performed during obesogenic pregnancy to improve offspring mitochondrial cardiac function". Paper presented in 55th Annual Scientific Meeting of the European Society for Clinical Investigation, 2021.
  16. Susana P. Pereira; Mariana S. Diniz; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Luís F. Grilo; Jelena Stev. "Could maternal obesity during gestation induce mitochondrial bioenergetic alterations in the offspring heart?". Paper presented in Olimpíadas Universitárias da Bioquímica, 2021.
  17. Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Mariana S. Diniz; Jelena Stevanovic-Silva; Jorge. "Prática de Exercício Físico Durante Diabetes Gestacional como Estratégia para a Modulação da Função Cardíaca da Gestante". Paper presented in 17.º Congresso Português de Diabetes, Virtual Meeting, 2021.
  18. Mariana S. Diniz; Susana P. Pereira; Carolina Tocantins; Óscar M. Rodrigues; João D. Martins; Luís F. Grilo; Jelena Stev. "Poderá a Obesidade Materna Alterar a Bioenergética Mitocondrial Cardíaca dos Descendentes?". Paper presented in 17.º Congresso Português de Diabetes, Virtual Meeting, 2021.
  19. Luís F. Grilo; Carolina Tocantins; Mariana S. Diniz; João D. Martins; Stephen Ford; Peter W. Nathanielsz; Paulo J. Olive. "Obesidade Gestacional Causa Stress Oxidativo e Dano Mitocondrial Fetal Hepático Com Maior Impacto No Lóbulo Direito Do Fígado". Paper presented in 17.º Congresso Português de Diabetes, Virtual Meeting, 2021.
  20. Susana P. Pereira; Diniz, Mariana S.; João D. Martins; Óscar M. Rodrigues; Carolina Tocantins; Grilo, Luís F.; et. al. "Preventing cardiac disease: maternal gestational exercise to mitigate obesity-induced cardiac metabolic impairment in the offspring". Paper presented in Society for Heart and Vascular Metabolism 2021: Metabolism at the crossroads of health and disease, 2021.
  21. Luís F. Grilo; João D. Martins; Mariana S. Diniz; Carolina Tocantins; Chiara H. Cavallaro; Inês Baldeiras; Teresa Cunha-. "Maternal Obesity During Pregnancy Induces Oxidative Stress and Mitochondria Functional Alterations in Sheep Maternal Liver". Paper presented in 68th Annual Meeting of the Society for Reproductive Investigation (SRI), 2021.
Journal article
  1. Kulovic-Sissawo, Azra; Tocantins, Carolina; Diniz, Mariana S.; Weiss, Elisa; Steiner, Andreas; Tokic, Silvija; Madreiter-Sokolowski, Corina T.; Pereira, Susana P.; Hiden, Ursula. "Mitochondrial Dysfunction in Endothelial Progenitor Cells: Unraveling Insights from Vascular Endothelial Cells". Biology 13 2 (2024): 70. http://dx.doi.org/10.3390/biology13020070.
    10.3390/biology13020070
  2. Mariana S. Diniz; Ursula Hiden; Inês Falcão-Pires; Paulo J. Oliveira; Luis Sobrevia; Susana P. Pereira. "Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2023): https://doi.org/10.1016/j.bbadis.2023.166834.
    10.1016/j.bbadis.2023.166834
  3. Carolina Tocantins; João D. Martins; Óscar M. Rodrigues; Luís F. Grilo; Mariana S. Diniz; Jelena Stevanovic-Silva; Jorge Beleza; et al. "Metabolic mitochondrial alterations prevail in the female rat heart 8 weeks after exercise cessation". European Journal of Clinical Investigation (2023): https://doi.org/10.1111/eci.14069.
    10.1111/eci.14069
  4. Diniz, Mariana S.; Magalhães, Carina C.; Tocantins, Carolina; Grilo, Luís F.; Teixeira, José; Pereira, Susana P.. "Nurturing through Nutrition: Exploring the Role of Antioxidants in Maternal Diet during Pregnancy to Mitigate Developmental Programming of Chronic Diseases". Nutrients 15 21 (2023): 4623. http://dx.doi.org/10.3390/nu15214623.
    10.3390/nu15214623
  5. Pereira, Susana P.; Diniz, Mariana S.; Tavares, Ludgero C.; Cunha-Oliveira, Teresa; Li, Cun; Cox, Laura A.; Nijland, Mark J.; Nathanielsz, Peter W.; Oliveira, Paulo J.. "Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model". International Journal of Molecular Sciences 24 20 (2023): 15192. http://dx.doi.org/10.3390/ijms242015192.
    10.3390/ijms242015192
  6. Grilo, Luís F.; Martins, João D.; Diniz, Mariana S.; Tocantins, Carolina; Cavallaro, Chiara H.; Baldeiras, Inês; Cunha-Oliveira, Teresa; et al. "Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress". Clinical Science 137 17 (2023): 1347-1372. http://dx.doi.org/10.1042/cs20230048.
    10.1042/cs20230048
  7. Elisa Weiss; Anna Schrüfer; Carolina Tocantins; Mariana Simoes Diniz; Boris Novakovic; Anke S. van Bergen; Azra Kulovic-Sissawo; et al. "Higher gestational weight gain delays wound healing and reduces expression of long non-coding RNA KLRK1-AS1 in neonatal endothelial progenitor cells". The Journal of Physiology (2023): https://doi.org/10.1113/JP284871.
    10.1113/JP284871
  8. Mariana S. Diniz; Luís F. Grilo; Carolina Tocantins; Inês Falcão-Pires; Susana P. Pereira. "Made in the Womb: Maternal Programming of Offspring Cardiovascular Function by an Obesogenic Womb". Metabolites (2023): https://doi.org/10.3390/metabo13070845.
    10.3390/metabo13070845
  9. Diniz, Mariana S.; Tocantins, Carolina; Grilo, Luís F.; Pereira, Susana P.. "The Bitter Side of Sugar Consumption: A Mitochondrial Perspective on Diabetes Development". Diabetology 3 4 (2022): 583-595. http://dx.doi.org/10.3390/diabetology3040044.
    10.3390/diabetology3040044
  10. Luís F. Grilo, Mariana S. Diniz, Carolina Tocantins, Ana L. Areia, Susana P. Pereira. "The Endocrine Metabolic Axis Regulation in Offspring Exposed to Maternal Obesity: Cause or Consequence in Metabolic Disease Programming?". Obesities 2 3 (2022): 236-255. http://dx.doi.org/10.3390/obesities2030019.
    10.3390/obesities2030019
  11. Carolina Tocantins; Mariana S. Diniz; Luís F. Grilo; Susana P. Pereira. "The birth of cardiac disease: Mechanisms linking gestational diabetes mellitus and early onset of cardiovascular disease in offspring". WIREs Mechanisms of Disease (2022): https://doi.org/10.1002/wsbm.1555.
    10.1002/wsbm.1555
  12. Grilo, Luís F.; Tocantins, Carolina; Diniz, Mariana S.; Gomes, Rodrigo Mello; Oliveira, Paulo J.; Matafome, Paulo; Pereira, Susana P.. "Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond". European Journal of Clinical Investigation (2021): http://dx.doi.org/10.1111/eci.13625.
    10.1111/eci.13625
Thesis / Dissertation
  1. "Made in the Womb: Maternal Programming of Cardiovascular Function". Master, Universidade de Coimbra, 2023.
  2. Diniz, Mariana S.. "Measurement of Respiratory Chain Enzyme Activities in Sheep Liver Homogenates". Degree, Universidade de Coimbra, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/12 Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling. Authors: Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena Stevanovic-Silva, Jorge Beleza, Pedro Coxito, David Rizo-Roca, Estela Santos-Alves, Manoel Rios, António J. Moreno, António Ascensão, José Magalhães, Paulo J. Oliveira. Mitochondria in Aging, Cancer and Cell Death (MAC 2023)
(Coimbra, Portugal)
2023/05 Offspring’s cardiac nitric oxide signaling is influenced by maternal physical exercise during an obesogenic pregnancy. Authors: Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena Stevanovic-Silva, Jorge Beleza, Pedro Coxito, David Rizo-Roca, Estela Santos-Alves, Manoel Rios, António J. Moreno, António Ascensão, José Magalhães, Paulo J. Oliveira. 1st FEBS Redox Medicine Workshop: from cellular signaling to systems physiology and therapeutic targets
(Luso, Portugal)
2023/05 Breaking the cycle: exercise during pregnancy can improve cardiovascular health in offspring of high fat, high sugar-fed mothers. Auhtors: Susana P. Pereira*, Mariana S. Diniz*, João D. Martins*, Óscar M. Rodrigues, Carolina Tocantins, Luís F. Grilo, Jelena Stevanovic-Silva, Jorge Beleza, Pedro Coxito, David Rizo-Roca, Estela Santos-Alves, Manoel Rios, António J. Moreno, António Ascensão, José Magalhães, Paulo J. Oliveira. Mitochondrial physiology, redox biology, and genetics (MitoPorto) 2023
(Porto, Portugal)
2022/06 Detraining of the Heart: impact of exercise practice exclusively during gestational diabetes mellitus on maternal cardiac mitochondria 56th Annual Scientific Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Bari, Italy)
2022/06 Impact of Gestational Exercise during Maternal Obesity in the Offspring Metabolic-Endocrine Environment: Role of Aging 56th Annual Scientific Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Bari, Italy)
2021 Maternal obesity induces fetal hepatic oxidative stress (OS) and mitochondrial damage predominantly in the right lobe 68th Annual Meeting of the Society for Reproductive Investigation (SRI)
Society for Reproductive Investigation (Boston, United States)
2021 Obesidade Gestacional Induz Stress e Dano Oxidativo Hepático Promovendo Macroautofagia No Fígado Materno 17.º Congresso Português de Diabetes, Virtual Meeting
Sociedade Portuguesa de Diabetologia (Portugal)
2021 Maternal obesity induces fetal hepatic oxidative stress (OS) and mitochondrial damage predominantly in the right lobe 68th Annual Meeting of the Society for Reproductive Investigation (SRI)
Society for Reproductive Investigation (Boston, United States)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/10 - 2024/05 PDBEB Annual Symposium (BEBDay 2024) (2024/05 - 2024/05)
2019 - 2019 Co-organizer of the activity "Dia Aberto de Bioquímica", promoted by Núcleo de Estudantes da Associação Académica de Coimbra (2019 - 2019)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/11/30 - 2023/12/02 Mitochondria in Aging, Cancer and Cell Death (MAC 2023), 30th November - 2nd December 2023, Coimbra, Portugal. Mitochondria in Aging, Cancer and Cell Death (MAC 2023)
2023/06/07 - 2023/06/09 57th Annual Scientific Meeting of the European Society for Clinical Investigation, 7-9th June 2023, Prague, Czech Republic. 57th Annual Scientific Meeting of the European Society for Clinical Investigation
2023/05/22 - 2023/05/25 1st FEBS Redox Medicine Workshop: from cellular signaling to systems physiology and therapeutic targets, 22-25th May 2023, Luso, Portugal. 1st FEBS Redox Medicine Workshop: from cellular signaling to systems physiology and therapeutic targets
2023/05/12 - 2023/05/13 Mitochondrial physiology, redox biology, and genetics (MitoPorto) 2023. 12th and 13th May 2023, Porto, Portugal Mitochondrial physiology, redox biology, and genetics (MitoPorto) 2023
2023/03/16 - 2023/03/18 19.º Congresso Português de Diabetes, 16-18th March 2023, Vilamoura, Portugal 19.º Congresso Português de Diabetes
2023/02/07 - 2023/02/08 17th edition of PDBEB symposium: Science Challenges: This Fight of Ours, 7th and 8th February 2023
Conference
 17th edition of PDBEB symposium: Science Challenges: This Fight of Ours
2022/03/28 - 2022/03/28 1st Workshop of the Research Unit Early Life Determinants
Workshop
 1st Workshop of the Research Unit Early Life Determinants
Medizinischer Universitat Graz, Austria
2021/11/17 - 2021/11/18 2nd Retreat of CIBB's metabolism, Aging and Disease Area 2nd Retreat of CIBB's metabolism, Aging and Disease Area
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2021/09/23 - 2021/09/24 Metabolism at the crossroads of health and disease 1st Virtual Meeting of the Society for Heart and Vascular Metabolism
Society for Heart and Vascular Metabolism, Germany
2021/06/28 - 2021/06/30 Metabolism in Health and Disease Nature Conferences: Metabolism in Health and Disease
2021/06/09 - 2021/06/11 The Micro Me’s: Exploring GutMicrobiota in Health and Disease 54th Annual Scientific Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation, Netherlands
2021/04/15 - 2021/04/15 Glucocorticoids, Developmental Programming and Ageing Glucocorticoids, Developmental Programming and Ageing
The Physiological Society, United Kingdom
2021/03/11 - 2021/03/17 17.º Congresso Português de Diabetes, Virtual Meeting
Conference
 17.º Congresso Português de Diabetes, Virtual Meeting
Sociedade Portuguesa de Diabetologia, Portugal
2021/03/06 - 2021/03/06 Olimpíadas Universitárias da Bioquímica
Conference
 Olimpíadas Universitárias da Bioquímica
Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra, Portugal
2020 - 2020 Speaker at the event: "Fórum Pedagógico - Speed Dating", promoted by Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra, Núcleo de Estudantes de Biologia da Associação Académica de Coimbra and Núcleo de Estudantes de Antropologia da Associação Académica de Coimbra
Meeting
2019/04/03 - 2019/04/03 Workshop "Suporte Básico de Vida", promoted by Associação Académica de Coimbra
2019 - 2019 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
Congress
 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation, Netherlands
2018 - 2018 Participation in the conferences: "Bioterrorismo - Armas Biológicas e Segurança Internacional", promoted by Núcleo de Estudantes da Associação Académica de Coimbra

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024/02 - Current Food & Function (2042-650X) The Royal Society of Chemistry
2023 - Current BBA Mol Basis Dis (0925-4439) Elsevier

Association member

Society Organization name Role
2020/02 - Current Sociedade Portuguesa de Diabetologia
2020 - Current European Society for Clinical Investigation Member
2017 - Current Associação Académica de Coimbra External Relations division member
2018/09 - 2019/06 Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra Administrator
2018 - 2019 Associação Académica de Coimbra International Relations division member
2017/09 - 2018/06 Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra Culture division member

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2016/12 Interviewed by "Diário de Notícias" Diário de Notícias
Distinctions

Award

2023 Prize for Best Flash Presentation presented by Mariana S. Diniz: Breaking the cycle: exercise during pregnancy can improve cardiovascular health in offspring of high fat, high sugar-fed mothers. Mitochondrial physiology, redox biology, and genetics (MitoP
2023 Prize for Best Oral Communication presented by Mariana S. Diniz: Offspring’s cardiac nitric oxide signaling is influenced by maternal physical exercise during an obesogenic pregnancy. 1st FEBS Redox Medicine Workshop: from cellular signaling to systems ph
2022 Prize for Best Oral Presentation presented by Luís F. Grilo Impact of Gestational Exercise during Maternal Obesity in the Offspring Metabolic-Endocrine Environment: Role of Aging
European Society for Clinical Investigation, Netherlands
2021 Award for the Best Fundamental Investigation Poster presented by Mariana S. Diniz
Sociedade Portuguesa de Diabetologia, Portugal
2021 Prize for Best Poster Presentation presented by Carolina Tocantins The effects of exercise during gestational diabetes mellitus on maternal cardiac metabolic function
Olimpíadas Universitárias da Bioquímica, Portugal
2020 Winner ESCI Poster/Oral Prize presented by Mariana S. Diniz
European Society for Clinical Investigation, Netherlands

Other distinction

2022 Doctoral Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
2020 Summer Course in Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
2020 Cambridge English Level 3 Certificate in ESOL International (Advanced) - Grade B, level C1
Cambridge English Language Assessment Spain and Portugal, Spain