Pedro Miguel Martins de Almeida Melo (CC17-D6DA-41CA)

Curriculum Vitae

Pedro Miguel Martins de Almeida Melo

Pedro Melo obtained his degree in Aquatic Sciences from the Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), University of Porto in 1995. He pursued further studies and earned a Master's degree in Quality Control (Environment) from the Faculty of Pharmacy (FFUP), University of Porto in 2000. In 2006, he successfully completed his PhD in Human Biology from the Faculty of Medicine (FMUP), University of Porto. Subsequently, from 2007 to 2011, Pedro Melo conducted a Postdoctoral project focusing on neuronal aging at the Institute for Molecular and Cell Biology, University of Porto. He also served as a Postdoctoral fellow in a project titled "Cognition and synaptic function in calcium channel disease" (PTDC/SAU-NEU/100701/2008), funded by FCT and carried out at the Institute for Molecular and Cell Biology (IBMC). Currently, Pedro Melo holds the position of Adjunct Professor at the Escola Superior da Saúde. Additionally, he is actively engaged as a researcher at the Centro Interdisciplinar de Investigação Marinha e Ambiental, University of Porto, where his research interests lie in exploring the impact of psychopharmaceuticals on the brain and retina of marine vertebrates. His expertise in quantitative chromatography, acquired during his Master's studies on Quality Control of water pollutants, has been extensively utilized throughout his scientific career. Since the year 2000, Pedro Melo has directed his research towards investigating the effects of psychoactive substances on the development and aging of the central nervous system. Particularly, he has focused on studying the correlation between methamphetamine use and accelerated aging with respect to neurochemistry and recognition memory. The data stemming from his PhD and Postdoctoral projects have contributed to six first-author publications in international scientific journals with peer review. Furthermore, Pedro Melo has contributed significantly to academia through various roles. He authored a chapter in the book "Bases Micronutricionales de la Salud Ocular" (2009) published by THEA LABS. He served as a co-supervisor for a PhD student from the Faculty of Medicine of Ribeirão Preto, Universidade de São Paulo (Brazil), whose research was financed by CAPES/4389/07-7 and conducted at FMUP and IBMC. Additionally, he possesses teaching and supervision experience at postgraduate levels (Ph.D. and Master levels) and has participated in PhD Evaluation Committees for doctoral dissertations. Moreover, Pedro Melo has editorial experience as the former editor of the European Journal of Clinical and Biomedical Sciences. He also serves as an ad hoc reviewer for various international peer-reviewed journals and collaborates on programs related to society and science. Since 2005, he has maintained a fruitful collaboration, encompassing research and postgraduate teaching, with Maria Dolores Pinazo Duran, head of the Unidad de Investigación Oftalmológica Santiago Grisólia and Professor at the Facultat de Medicine I Odontologia of the Universitat de Valencia, Spain.

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Identification

Personal identification

Full name: Pedro Miguel Martins de Almeida Melo

Citation names

Melo, Pedro

Author identifiers

Ciência ID: CC17-D6DA-41CA

Addresses

Rua Dr. António Bernardino de Almeida, 400, 4200-072, Porto, Porto, Portugal (Professional)

Knowledge fields

Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2011/12/15 - 2012/12/14 Concluded	Cognition and synaptic function in calcium channel disease (Pós-doutoramento) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2007/03/01 - 2011/02/28 Concluded	The effect of Methamphetamine on Neuronal ageing: correlation of Molecular Markers with Memory (Pós-doutoramento) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2006/12/14 Concluded	Biologia Humana (Doutoramento) Major in Biologia Humana Universidade do Porto Faculdade de Medicina, Portugal "Efeitos da exposição pré-natal à methamphetamina no sistema visual do Rato" (THESIS/DISSERTATION)	Aprovado
2000/01/21 Concluded	Controlo de Qualidade (Mestrado) Major in Ambiente Universidade do Porto Faculdade de Farmácia, Portugal "Doseamento de compostos fenólicos em diferentes matrizes aquosas usando a extracção em fase sólida e a microextracção em fase sólida seguida de análise por cromatografia líquida de alta resolução e detecção por fotodíodos" (THESIS/DISSERTATION)
1995/09/08 Concluded	Ciências do Meio Aquático (Licenciatura) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	14

Affiliation

Science

	Category Host institution	Employer
2013 - Current	Visiting Researcher (Research)	Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

2001/07/01 - 2012/12/04	Researcher (Research)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

1999 - 2000	Research Trainee (Research)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2024/03/01 - Current	Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

2018/09/15 - 2024/02/29	Invited Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

2017/03/10 - 2024/02/29	Invited Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal

2010/10/01 - 2018/09/14	Invited Assistant (Polytechnic Teacher)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Projects

Grant

	Designation	Funders
2011 - 2012	Cognition and synaptic function in calcium channel disease info:eu-repo/grantAgreement/FCT/5876-PPCDTI/100701/PT Post-doc Fellow Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Universidade do Algarve Faculdade de Ciências e Tecnologia Concluded
2007/07/01 - 2011	THE EFFECT OF METHAMPHETAMINE ON NEURONAL AGEING: CORRELATION OF MOLECULAR MARKERS WITH MEMORY info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBPD2%F264772%F2006/PT Post-doc Fellow Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Universidade do Algarve Faculdade de Ciências e Tecnologia Concluded
2001 - 2005	Effects of prenatal exposure to methamphetamine in the visual system of the rat SFRH/BD/3395/2000 PhD Student Fellow Universidade do Porto Faculdade de Medicina, Portugal	Concluded
1999 - 2000	P/SAU/12287/98 P/SAU/12287/98 Research Fellow	Concluded

Outputs

Publications

Book chapter

Melo, Pedro. "Los grupos básicos de nutrientes: Los glúcidos, los lípidos, las proteínas". In BASES MICRONUTRICIONALES DE LA SALUD OCULAR. Barcelona, Spain: THEA LABS, 2009.
Published • 10.2307/j.ctvhn0c5z.11

Journal article

Magalhães, Ana; Valentim, Ana; Venâncio, Carlos; Pereira, Mariana; Melo, Pedro; Summavielle, Teresa; Antunes, Luis; et al. "Ketamine alone or combined with midazolam or dexmedetomidine does not affect anxiety-like behaviours and memory in adult Wistar rats". Laboratory Animals 51 2 (2016): 147-159. http://dx.doi.org/10.1177/0023677216652380.
10.1177/0023677216652380
Alves, C.J.; Magalhães, A.; Melo, P.; de Sousa, L.; Tavares, M.A.; Monteiro, P.R.R.; Summavielle, T.; et al. "Long-term effects of chronic cocaine exposure throughout adolescence on anxiety and stress responsivity in a Wistar rat model". Neuroscience 277 (2014): 343-355. http://dx.doi.org/10.1016/j.neuroscience.2014.07.008.
10.1016/j.neuroscience.2014.07.008
Melo, Pedro; Magalhães, Ana; Alves, Cecília J.; Tavares, Maria Amélia; de Sousa, Liliana; Summavielle, Teresa; Moradas-Ferreira, Pedro. "Methamphetamine mimics the neurochemical profile of aging in rats and impairs recognition memory". NeuroToxicology 33 3 (2012): 491-499. http://dx.doi.org/10.1016/j.neuro.2012.03.002.
10.1016/j.neuro.2012.03.002
Melo, Pedro; Zanon-Moreno, Vicente; Alves, Cecília Juliana; Magalhães, Ana; Tavares, Maria Amélia; Pinazo-Duran, Maria Dolores; Moradas-Ferreira, Pedro. "Oxidative stress response in the adult rat retina and plasma after repeated administration of methamphetamine". Neurochemistry International 56 3 (2010): 431-436. http://dx.doi.org/10.1016/j.neuint.2009.11.017.
10.1016/j.neuint.2009.11.017
DeMaman, A S; Melo, P; Homem, J M; Tavares, M A; Lachat, J-J. "Effectiveness of iron repletion in the diet for the optic nerve development of anaemic rats". Eye 24 5 (2009): 901-908. http://dx.doi.org/10.1038/eye.2009.205.
10.1038/eye.2009.205
Magalhães, Ana; Melo, Pedro; Alves, Cecília Juliana; Tavares, Maria Amélia; de Sousa, Liliana; Summavielle, Teresa. "Exploratory Behavior in Rats Postnatally Exposed to Cocaine and Housed in an Enriched Environment". Annals of the New York Academy of Sciences 1139 1 (2008): 358-365. http://dx.doi.org/10.1196/annals.1432.046.
10.1196/annals.1432.046
Alves, Cecília Juliana; Magalhães, Ana; Summavielle, Teresa; Melo, Pedro; De Sousa, Liliana; Tavares, Maria Amélia; Monteiro, Pedro R.R.. "Hormonal, Neurochemical, and Behavioral Response to a Forced Swim Test in Adolescent Rats throughout Cocaine Withdrawal". Annals of the New York Academy of Sciences 1139 1 (2008): 366-373. http://dx.doi.org/10.1196/annals.1432.047.
10.1196/annals.1432.047
Melo, Pedro; Pinazo-Durán, Maria Dolores; Salgado-Borges, José; Tavares, Maria Amélia. "Correlation of axon size and myelin occupancy in rats prenatally exposed to methamphetamine". Brain Research 1222 (2008): 61-68. http://dx.doi.org/10.1016/j.brainres.2008.05.047.
10.1016/j.brainres.2008.05.047
RODRIGUES, L. G; MELO, P.; SILVA, M. C.; TAVARES, M. A.. "Effects of Postnatal Exposure to Methamphetamine on the Development of the Rat Retina". Annals of the New York Academy of Sciences 1074 1 (2006): 604-619. http://dx.doi.org/10.1196/annals.1369.059.
10.1196/annals.1369.059
MELO, P.; RODRIGUES, L. G; SILVA, M. C.; TAVARES, M. A.. "Effects of Prenatal Exposure to Methamphetamine on the Development of the Rat Retina". Annals of the New York Academy of Sciences 1074 1 (2006): 590-603. http://dx.doi.org/10.1196/annals.1369.058.
10.1196/annals.1369.058
MAGALHAES, A.; SUMMAVIELLE, T.; MELO, P.; ROSA, R.; TAVARES, M. A.; DE SOUSA, L.. "Prenatal Exposure to Cocaine and Enriched Environment: Effects on Social Interactions". Annals of the New York Academy of Sciences 1074 1 (2006): 620-631. http://dx.doi.org/10.1196/annals.1369.060.
10.1196/annals.1369.060
Melo, Pedro; Moreno, Vicente Zanón; Vázquez, Sheila Pons; Pinazo-Durán, Maria Dolores; Tavares, Maria Amélia. "Myelination changes in the rat optic nerve after prenatal exposure to methamphetamine". Brain Research 1106 1 (2006): 21-29. http://dx.doi.org/10.1016/j.brainres.2006.05.020.
10.1016/j.brainres.2006.05.020
Magalhães, Ana; Summavielle, Teresa; Melo, Pedro; Tavares, Maria Amélia; Sousa, Liliana de. "Prenatal cocaine exposure: effects on locomotor activity in rat offspring". Environmental Toxicology and Pharmacology 19 3 (2005): 767-773. http://dx.doi.org/10.1016/j.etap.2004.12.043.
10.1016/j.etap.2004.12.043
Melo, Pedro; Rodrigues, Lorena G.; Pinazo-Durán, Maria Dolores; Tavares, Maria Amélia. "Methamphetamine and lipid peroxidation in the rat retina". Birth Defects Research Part A: Clinical and Molecular Teratology 73 6 (2005): 455-460. http://dx.doi.org/10.1002/bdra.20138.
10.1002/bdra.20138

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2018/02/01	Metanfetamina e o envelhecimento.	XIII Encontro Nacional de Estudantes de Engenharia Biomédica (ENEEB) Instituto Superior de Engenharia (Porto, Portugal)
2014/04/08	Ética na experimentação animal	Universidade Lusófona (Porto , Portugal)
2010/09/23	Ageing with methamphetamine; Drugs of Abuse as research models for neurodegenerative disorders Symposium	I International Congress of Health Gaia Politécnico do Porto (Vila Nova de Gaia, Portugal)
2007	Effect of methamphetamine on protein oxidation in the rat brain hippocampus	ESAAM 1st Link;Age / Conference on Longevity ESAAM (Dessau, Germany)
2006/05/31	Prenatal exposure to methamphetamine induces alterations in myelination of the rat optic nerve	PhD training;internal seminars Instituto de Biologia Molecular e Celular (Porto, Portugal)
2005/05/11	Prenatal methamphetamine effects in the developing optic nerve	Neurobiology and Drugs of Abuse Instituto de Biologia Molecular e Celular (Porto, Portugal)
2003	Comparación de los efectos de la exposición prenatal a drogas de diseño o alcohol sobre el sistema visual	79 Congreso de la Sociedad Española de Oftalmologia (Valencia, Spain)
2001	Efeito da exposição pósnatal à metanfetamina na retina do Rato. Estudo immunocitoquímico	Congresso da Sociedade Portuguesa de Oftalmologia Jornadas de Investigação (Portugal)
2000	Efeito da exposição pósnatal à metanfetamina na retina do Rato	Congresso da Sociedade Portuguesa de Oftalmologia Jornadas de Investigação (Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2020 - 2021/07/01	Retinal and Visual Implications of embryonic exposure to antidepressants on Zebrafish Supervisor	Mestrado em Bioquímica em Saúde (Master) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/03/01 - 2020/07/31	Perfil génico no desenvolvimento do sistema visual do zebrafish exposto a psicofármacos Supervisor	Biotecnologia Medicinal (Degree) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019 - 2019/09	Efeitos da Exposição embrionária à fluoxetina e pirimicarb na expressão genica no peixe-zebra Supervisor	Biotecnologia Medicinal (Degree) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2018 - 2018/07	Effects Of Embryonic Exposure To Venlafaxine On A Zebrafish Model Supervisor	Biotecnologia Medicinal (Degree) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2017 - 2017/10/10	Resposta Bioquímica à Toxicidade da água do Rio Ave com Physa Acuta Supervisor	Ciências do Meio Aquático (Degree) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 - 2015	Avaliação do stresse oxidativo em retina de robalo após exposição a psicofármacos Supervisor	Genética e Biotecnologia (Degree) Universidade de Trás-os-Montes e Alto Douro, Portugal
2014 - 2014	Estudo preliminar de potencias efeitos da fluoxetine no desenvolvimento do sistema visual do peixe zebra Co-supervisor	Ciências do Meio Aquático (Degree) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2013	In training period at the Genetics of Cognitive Dysfunction Group Co-supervisor	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008 - 2008	Estudo Ultraestrutural do Nervo Óptico de Ratos Wistar após Recuperação da Anemia Ferropriva (CAPES/4389/07) Co-supervisor	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2011/06/07	Alteraciones en el desarrollo de la retina y el nervio óptico inducidas por la exposición crónica a etanol en la rata (RD778/1998) President of the jury	Sheila Pons Vasquez (PhD) Universitat de València Facultat de Medicina i Odontologia, Spain
2008	Estrés oxidativo en el glaucoma primario de ángulo abierto. Prevención de la ceguera por glaucoma. (Thesis) Arguer	Vicente Zanon Moreno (PhD) Universitat de València Facultat de Medicina i Odontologia, Spain