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Carmen Jerónimo is the Director of the Research Center, Group Leader of the Cancer Biology & Epigenetics Group and the Scientific Coordinator of the Biobank at the Portuguese Oncology Institute of Porto (IPO Porto), as well as a guest Full Professor in the Department of Pathology and Molecular Genetics and the Director of the Master Course in Oncology at the University of Porto, teaching Pathology and Cancer Epigenetics, both undergraduate and Post-graduation Courses. She obtained her BSc in Biology (1994), MSc in Oncology (1998), PhD in Biomedical Sciences (2001), and Habilitation in Pathology and Molecular Genetics (2011) at the University of Porto. She performed her PhD project at Johns Hopkins University (JHU), USA, supervised by Prof. David Sidransky under the GABBA Program, working on prostate cancer genetic and epigenetic alterations. From 2002 until 2007, she was a Post-doctoral Fellow and Invited Researcher at IPO Porto, in collaboration with JHU, working on the detection of neoplastic cells by DNA-based technology in clinical samples obtained from non-invasive or minimally invasive methods. In 2008 she established her independent group at IPO Porto, working on Cancer Biology and Epigenetics (FCT-2008 Science Program). She has supervised/co-supervised 7 Post-Doctoral fellows, 14 PhD students, 83 master's students, and several undergraduates. Presently she mentors 2 Junior Researchers (R2), 15 PhD students (7 as co-supervisor), and 6 Master students. As an independent Researcher, she served as PI/co-PI of more than 20 grants. She participated in 14 other projects granted from different National and International agencies under competitive concurrence (> 6M euros). She has authored/ co-authored more than 300 international scientific publications including 13 book chapters and 84 review articles (H-index 55; WoS 12/2023), including in first quartile (Q1) journals; Clin Cancer Res, Cancers, Cancer Letters, Cell Death Dis, Clinical Epig, Br J Cancer, Eur J Cancer, J Cell Mol Med, J Hematol Oncol, JNCI, Mol Cancer, Mol Oncol and Nat Commun, Oncogene, PNAS]. In 2012 she collaborated on a patent submission (Methods and biomarkers for detection of bladder cancer US 20130210011/ EP 2630261 A1/ WO 2012052844 A1). Her research interests are focused on characterizing the epigenome of tumor cells and identifying functional changes involved in cell epigenetic homeostasis breakdown. In the context of Personalized Medicine, she works on developing new cancer epigenetic biomarkers based on liquid biopsies and drug discovery based on the modulation of epigenetic aberrations. Owing to the relevance that Immuno-oncology has demonstrated in recent years, she is also investigating the epigenetic expression modulation of biomolecules involved in immune checkpoint regulation, aiming to improve immunotherapeutic strategies combined with epi-drugs. More recently, she started tackling the contribution of deregulated non-coding RNAs and their interaction with other epigenetic mechanisms in malignant transformation. Currently, she serves as Section Editor of Clinical Epigenetics and Associate Editor of Frontiers in Genetics and Frontiers in Cell and Developmental Biology. She is also an MC member of COST Action European Epitranscriptomics Network- CA16120-EPITRAN and Chair of the Board- Section of Urological Research (ESUR) of the European Association of Urology (EAU). She usually acts as a grant reviewer for multiple national (FCT Investigator Call 2013 e 2015) and international agencies including Cancer Research UK; Binational Science Foundation Israel; Swiss National Science Foundation, WILLIAMS BARKER, MRC, UK; Swiss League Against Cancer-KFS; FWF Austrian Science Fund; PROSTATE CANCER UK; Agence Nationale de la Recherche, FR; Fundaciò La Marató, SP; Fonds National de la Recherche Luxembourg; Institut National Du Cancer, France; Novo Nordik Foden, Norway.
Identification

Personal identification

Full name
Carmen Jerónimo
Date of birth
1972/06/02
Gender
Female

Citation names

  • Jerónimo, Carmen

Author identifiers

Ciência ID
CE16-29CB-EDD1
ORCID iD
0000-0003-4186-5345
Researcher Id
H-3284-2013
Scopus Author Id
57197057169

Email addresses

  • carmenjeronimo@ipoporto.min-saude.pt (Professional)
  • cljeronimo@icbas.up.pt (Professional)

Telephones

Telephone
  • 225084000 Ext.: 7264 (Professional)

Addresses

  • Centro de Investigação (LAB 3); Instituto Português de Oncologia do Porto de Francisco Gentil, E.P.E.. R. Dr. António Bernardino de Almeida, 4200-072, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Basic Medicine - Pathology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Upper intermediate (B2)
Education
Degree Classification
2011/11/17
Concluded
Habilitation (Agregação) for full professorship in Pathology and Molecular Genetics/ Patologia e Genética Molecular (Título de Agregado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Curricular Unit:Cancer and Epigenetics ; Lesson: Development of epigenetic biomarkers for detection of urologic tumors" (THESIS/DISSERTATION)
Approved by unanimity
1997/09 - 2001/10/24
Concluded
PhD in Biomedical Sciences/Ciências Biomédicas (Doutoramento)
Major in Cancer Genetics & Epigenetics
Universidade do Porto, Portugal
"Molecular Detection of Prostate Cancer" (THESIS/DISSERTATION)
Approved by unanimity
1998
Concluded
MSc in Oncology/Oncologia (Mestrado)
Major in Molecular Oncology/Oncologia Molecular
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
""Transitional cell carcinoma of the Bladder: expression of p53, bcl-2, nm23, CD44s, CD44v6, and BL2-10D1 and their relation to histologic grade and stage"" (THESIS/DISSERTATION)
Very Good by unanimity
1994
Concluded
BSc in Biology/Biologia (Licenciatura)
Major in Ramo Científico-Tecnológico
Universidade do Porto Faculdade de Ciências, Portugal
"n/a" (THESIS/DISSERTATION)
14,45 (out of 20)
Affiliation

Science

Category
Host institution
Employer
2009/07/01 - Current Auxiliary Researcher (Research) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2004/10/01 - 2009/06/30 Invited Auxiliary Researcher (Research) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2003/07/01 - 2003/12/31 Visiting Researcher (Research) The Johns Hopkins University School of Medicine, United States
The Johns Hopkins University School of Medicine, United States

Teaching in Higher Education

Category
Host institution
Employer
2020/09/01 - Current Invited Full Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/03/01 - 2021/06/30 Visiting Professor (University Teacher) Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Medicina di Precisione, Italy
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Medicina di Precisione, Italy
2009/09/01 - 2020/08/31 Invited Associate Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2016 Visiting Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2004/09/01 - 2009/06/30 Assistant Professor (University Teacher) Universidade Fernando Pessoa, Portugal
2006 - 2009 Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Positions / Appointments

Category
Host institution
Employer
2021/11/01 - Current Director of the IPO Porto Research Center (CI-IPOP) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2021 - Current Member of the executive board of RISE & coordinator of the thematic line-Cancer Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
RISE - Health Research Network, Portugal
(...)
2021 - Current Member of the Joint Management Committee of the Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
(...)
2016/09/24 - Current Director of the Master in Oncology Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/09 - Current President of the Scientific Committee of the Master course in Oncology Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/01/01 - Current Scientific coordinator of the IPO Porto' Biobank Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2008/01/01 - Current Scientific coordinator of the Cancer Biology & Epigenetics Group Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2008/01/01 - Current IPO Porto Research Center Scientific commitee Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2012/08 - 2016 Member of the Scientific Committee of the Master course in Oncology Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Others

Category
Host institution
Employer
2002/10/01 - 2004/08/31 Post-Doctoral fellow (FCT Grant SFRH/BPD/8031/2002) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
1997/10/01 - 2001/09/30 PhD Student; FCT fellowship-PRAXIS XXI/BD/13398/97 Fundação para a Ciência e a Tecnologia, Portugal
The Johns Hopkins University School of Medicine, United States
(...)
1996/09/01 - 1997/09/30 MSc Student; FCT Fellowship-PRAXIS XXI Grant BM/8579/96 Fundação para a Ciência e a Tecnologia, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
(...)
1994/09 - 1995/02 BSc Trainee; Scholarship PRODEP II (1/3.2/PRODEP/1993) Universidade do Porto Faculdade de Ciências, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Projects

Grant

Designation Funders
2019 - Current Immunoprofiling characterisation of clinical samples by IHC and gene expression analysis and correlation with clinical outcomes in support of translational medicine strategies for ICOS and PD-L1-IC antibody therapeutics.
KYMAB_IPOPORTO_01
Other
2024/01 - 2027/12 PROSTAMET A Comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve Prostate Cancer Management and Educate Young Researchers in Tackling Complex Disease
Co-Principal Investigator (Co-PI)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Marie Curie
2023/03/01 - 2026/02/28 On the crossroads of Immuno-Epigenetics for targeting advanced Prostate Cancer
2022.04809.PTDC
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - 2025/12/31 Circulating tumour microenvironment components as Urothelial Cancer Immunotherapy Response Predictors
TRANSCAN3/0001/2021
Principal investigator
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Health Research Network: From Lab to Community Health
LA/P/0053/2020
Universidade do Porto Faculdade de Medicina, Portugal

Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal

Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade NOVA de Lisboa, Portugal

Escola Superior de Enfermagem do Porto, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Universidade de Aveiro, Portugal

Universidade da Madeira, Portugal

Universidade do Algarve, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2024/12/31 GLYCOTARGET. A NEW FRONTIER IN EXTRACELLULAR VESICLE-MEDIATED CANCER IMMUNOMODULATION
PTDC/MEC-ONC/0491/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto de Astrofísica e Ciências do Espaço, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01 - 2024/12 Research Center of Portuguese Oncology Institute of Porto - Programatic Funding
UIDP/00776/2020
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01 - 2024/12 Research Center of Portuguese Oncology Institute of Porto - Base Funding
UIDB/00776/2020
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/12/01 - 2024/11/30 diffNET - Restoring differentiation in cancer cells by manipulating RNA-binding protein NETworks
PTDC/BIA-CEL/0456/2021
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Fundação Champalimaud, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/12 - 2024/09/11 Decoding the role of extracellular vesicles in prostate cancer bone metastasis
2022.05135.PTDC
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Fundação Champalimaud, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019 - 2024/03/31 MindGAP: Bridging the gap between Mind, Brain and Body: exosome role and monitoring
H2020-FETOPEN-2018-2020
10.3030/829040
WP leader
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

University of Oulu, Finland, Finland

Universidade de Coimbra Departamento de Engenharia Quimica, Portugal

Linneuniversitet Institutionen for kemi och biomedicin, Sweden

Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal
European Union
Ongoing
2021/03/01 - 2024/02/29 CyclicCell - Cyclic loading effects in bladder cancer cells
PTDC/EME-APL/1342/2020
Co-Principal Investigator (Co-PI)
Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia, Portugal

Associated Laboratory for Energy Transports and Aeronautics, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/06/01 - 2023/11/30 The Porto Comprehensive Cancer Center
PINFRA03/72678/2020
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2022/01/17 - 2023/07/16 Bridging iRon metabolism and immunE cells at the irrAdiateD tumOUr microenvironmenT to identify novel therapeutic targets in rectal cancer
EXPL/BIA-CEL/1225/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016/01 - 2022/12 Assessment and validation of a panel of methylation-based Biomarkers in cell free DNA for Detection of recurrent first primary cancer (RFPC) and second primary cancers (SPC)
(CI-IPOP-74-2016)
Principal investigator
Research Centre of Portuguese Oncology Institute
2018/08/10 - 2021/12/31 ACCuseD renAl Cell Carcinoma Detection Renal Cancer detection: a translational metabolomics research based on Volatile Organic Compounds fingerprinting
PTDC/SAU-SER/30388/2017
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Fundação Ensino e Cultura Fernando Pessoa, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/01 - 2021/06/30 EpiMarkGermCell-DEVELOPMENT OF NOVEL PROGNOSTIC AND PREDICTIVE EPIGENETIC BIOMARKERS FOR MALIGNANT TESTICULAR GERM CELL TUMORS
POCI-01-0145-FEDER-29043
PTDC/MEC-URO/29043/2017
Co-Principal Investigator (Co-PI)
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2020 ESTIMA: Early stage cancer treatment driven by context of molecular imaging
ESTIMA-NORTE-01-0145-FEDER-000027
Researcher
Fundo Regional para a Ciência e Tecnologia
2019/01/01 - 2019/12/31 Portuguese Oncology Institute - Porto Research Center
UID/DTP/00776/2019
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/09/20 - 2019/12/22 New natural and synthetic compounds for the treatment of hormone-resistant tumors
SAICT-POL/24156/2016
Co-Principal Investigator (Co-PI)
Instituto Politécnico do Porto, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015/01 - 2017/12 Epigenetic signature of prostate cancer stem cells
(CI-IPOP-17-2015)
Researcher
Research Centre of Portuguese Oncology Institute of Porto
2012/03/15 - 2015/07/14 Epigenetic regulation in mammary stem/progenitor cells and its contribution to malignant transformation
PTDC/SAU-ONC/118346/2010
Principal investigator
Universidade de Aveiro, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

University of Houston, United States

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/04 - 2014/03 Discovery of novel microRNA genes epigenetically down-regulated in prostate cancer
EXPL/BIM-ONC/0556/2012
Principal investigator
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 776 - 2011-2012
PEst-OE/SAU/UI0776/2011
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/01 - 2013/12 Genomic and phenotypic impact of the combined use of epigenetic modulating drugs in prostate cancer
NA
Principal investigator
Liga Portuguesa Contra o Cancro – Núcleo Regional do Norte (Portuguese League Against Cancer – North)
2010/01 - 2012/12 Project EpiDiaCan: Development of sensitive methodologies for exploitation of early epigenetic marker diagnosis in major types of cancer
FP7-241783
Principal investigator
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
European Commission
2008/05 - 2010/04 Screening for urological neoplasias by new epigenetic biomarkers
96474
Principal investigator
Fundação Calouste Gulbenkian
2002/10/01 - 2004/09/30 DETECTION OF NEOPLASTIC CELLS BY DNA-BASED TECHNOLOGY IN CLINICAL SAMPLES OBTAINED BY NONINVASIVE OR MINIMALLY INVASIVE METHODS
SFRH/BPD/8031/2002
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
1997/10/01 - 2001/09/30 GABBA PhD Program_Academic Year_MANDATORY MODULES: CELL BIOLOGY, DEVELOPMENTAL BIOLOGY, MOLECULAR BIOLOGY, BIOPATHOLOGY, FORMAL GENETICS IMMUNOLOGY, NEUROBIOLOGY, NEUROENDOCRINOLOGY, ONCOBIOLOGY
PRAXIS XXI/BD/13398/97
Fundação para a Ciência e a Tecnologia
Concluded
1996/10/01 - 1997/09/30 STUDY OF SOME BIOMOLECULAR PARAMETERS IN BLADDER NEOPLASMS - MASTERS IN ONCOLOGY
PRAXIS XXI/BM/8579/96
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Jerónimo, Carmen. Histone Modifications in Therapy (Translational epigenetics). United Kingdom: Academic Press 2020. 2020.
    Published • Editor
Book chapter
  1. Sarmento Ribeiro, Ana Bela; Botelho, Maria Filomena; Gonçalves, Ana Cristina; Melo, Joana Barbosa; Laranjo, Mafalda; Alves, Raquel; Jorge, Joana; et al. "Aging-related neoplasia". In Aging, 547-575. Elsevier, 2023.
    10.1016/b978-0-12-823761-8.00026-4
  2. Matos, Bárbara; Howl, John; Jerónimo, Carmen; Fardilha, Margarida. "Exploring glycolytic adaptations in cancer cells". In Glycolysis: Tissue-specific Metabolic regulation in physio-pathological conditions. Elsevier, 2023.
    In press
  3. Constâncio, Vera; Henrique, Rui; Jerónimo, Carmen. "Extracellular vesicle-contained microRNAs in prostate cancer: From pathophysiology to emerging translational opportunities". In MicroRNA in Human Malignancies, 291-299. Elsevier, 2022.
    Published • 10.1016/b978-0-12-822287-4.00028-1
  4. João Lobo; Carmen Jerónimo; Rui Henrique. "Targeting chromatin remodelers in urological tumors". 2020.
    10.1016/B978-0-12-816422-8.00008-8
  5. Ramalho-Carvalho, J; Henrique, R; Jerónimo, C. "Methylation-Specific PCR". In Methods in Molecular Biology, edited by Jorg Tost, 1868-1868. Germany: Springer Berlin Heidelberg, 2018.
    10.1007/978-3-540-47648-1_3686
  6. Vieira, Filipa Quintela; Almeida-Rios, Diogo; Graça, Inês; Henrique, Rui; Jerónimo, Carmen. "Histone Posttranslational Modifications and Chromatin Remodelers in Prostate Cancer". In Epigenetic Biomarkers and Diagnostics, edited by Garcia Gímenez, JL, 447-465. Elsevier, 2016.
    Published • 10.1016/b978-0-12-801899-6.00022-x
  7. Henrique, Rui; Jerónimo, Carmen. "GSTP1 Hypermethylation for Prostate Cancer Detection". In Prostate Cancer Screening, 279-288. Humana Press, 2009.
    10.1007/978-1-60327-281-0_19
  8. Jerónimo, C.; Henrique, R.; Sidransky, D.. "Uses of DNA methylation in cancer diagnosis and risk assessment". edited by Esteller, M., 11-26. 2004.
Conference abstract
  1. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Montezuma, Diana; Lourenço, Catarina; Oliveira, Miguel Carlos; Constâncio, Vera; Sequeira, José pedro; et al. "P17 - Urinary extracellular vesicles isolation: Improving the differential ultracentrifugation method for biomarker research". Paper presented in 29th Meeting of the EAU Section of Urological Research (ESUR) in collaboration with the EAU Section of Uropathology (ESUP), Basel, 2023.
    Published
Conference paper
  1. Bárbara Matos; John Howl; Carmen Jerónimo; Margarida Fardilha. "CAVPENET Decreases Prostate Cancer Cells Proliferation and Invasion through Modulation of Protein Phosphatase Activity". 2023.
    10.3390/blsf2023021017
Conference poster
  1. Filipa D. dos Reis; Lobo, João; Carneiro, Isa; Freitas, Rui; Henrique, Rui; Jerónimo, Carmen; Correia, Margareta. "Harnessing epigenetic mechanisms to modulate the NK cell-mediated killing of PCa cells". Paper presented in FCT Encontro Ciência 2024, 2024.
  2. Macedo-Silva, Catarina; Angela Albuquerque-Castro; Lencart, Joana; Carneiro, Isa; Nuno Tiago Tavares; Barros-Silva, Daniela; João Lobo; et al. "Epigenetic reprogramming as Hallmark of prostate cancer radiobiology". Paper presented in Young Researchers Day IPO Porto, 2023.
  3. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Lourenço, Catarina; Sequeira, José pedro; Salta, Sofia; Montezuma, Diana; Oliveira, Miguel Carlos; et al. "Discovering urinary extracellular vesicles' miRNAs as bladder cancer biomarkers". Paper presented in 1st Young Researchers' Day, 2023.
  4. Lourenço, C; Maia, J; Suriyanarayanan, S; Marques, P; Nicholls, I; Carvalho, A. ; Jerónimo, Carmen. "EMBRACIVE – A microfluidic assisted technology for non-invasive identification and characterization of extracellular vesicles in bladder cancer patients". Paper presented in 1st Young Researcher’s Day, 2023.
  5. Filipa D. dos Reis; Lobo, João; Carneiro, Isa; Freitas, Rui; Henrique, Rui; Jerónimo, Carmen; Correia, Margareta. "EZH2 inhibition leads to increased NK cell-mediated killing of prostate cancer cells". Paper presented in III ASPIC-ASEICA International Meeting, 2023.
  6. Macedo-Silva, Catarina; Vera Miranda-Gonçalves; Nuno Tiago Tavares; Barros-Silva, Daniela; Angela Albuquerque-Castro; Lencart, Joana; Carneiro, Isa; et al. "Epigenetic modulation of p53 by GSK-J4 attenuates prostate cancer radioresistance". Paper presented in ImmunoRad, 2023.
  7. Matos, Bárbara; Monteiro, Maria V.; Bernardino, Raquel L.; Alves, Marco G.; Oliveira, Pedro F.; Gaspar, Vitor; Mano, Joao F.; et al. "Modulação de complexos da proteína fosfatase 1 usando péptidos para tratamento do cancro da próstata". Paper presented in 5º ENJIO - 5º Encontro nacional de jovens investigadores em oncologia, 2023.
  8. Castro, Maria Miguel ; Esquível, Catarina; Jesus, Tito T.; Ribeiro, Ana Sofia; Sousa, Bárbara; Jerónimo, Carmen; Paredes, Joana. "O impacto da perda de adesão célula-célula na sobrevivência de êmbolos tumorais de cancro da mama inflamatório". Paper presented in ENJIO 2023, Liga Portuguesa Contra o Cancro, 2023.
  9. Matos, Bárbara; Monteiro, Maria V.; Bernardino, Raquel L.; Alves, Marco; Oliveira, Pedro; Gaspar, Vitor; Mano, Joao F.; et al. "CAVPENET-induced modulation of PP1 activity suppresses the growth of 2D and 3D prostate cancer cultures by inducing metabolic reprogramming". Paper presented in Signal regulation by protein phosphatases: Mechanisms and pathways, 2023.
  10. Filipa D. dos Reis; Jerónimo, Carmen; Correia, Margareta. "Modulating PCa cell immunogenicity with EZH2i to increase NK cell-mediated killing". Paper presented in IMMUNO-model COST Action CA21135 Meeting, 2023.
  11. Castro, Maria Miguel ; Esquível, Catarina; Jesus, Tito T.; Ribeiro, Ana Sofia; Sousa, Bárbara; Jerónimo, Carmen; Paredes, Joana. "The impact of cell-cell adhesion disruption on the survival of Inflammatory Breast Cancer tumor emboli". Paper presented in 29th Porto Cancer Meeting, 2023.
  12. Estêvão, Diogo; da Cruz-Ribeiro, Miguel; Macedo-Silva, Catarina; Jerónimo, Carmen; Olga Sousa; De Wever, Olivier; Maria José Oliveira; Cruz, Tânia. Corresponding author: da Cruz-Ribeiro, Miguel. "Dissecting the Radiotherapy-mediated changes in Rectal Cancer Immune Profile". Paper presented in XLVIII SPI Annual Meeting, 2023.
  13. Castro, Maria Miguel ; Esquível, Catarina; Jesus, Tito T.; Ribeiro, Ana Sofia; Sousa, Bárbara; Jerónimo, Carmen; Paredes, Joana. "Effect of cell-cell adhesion disruption on anoikis-resistance and aggregation in Inflammatory Breast Cancer Cells". Paper presented in 5th PhDay, 2022.
  14. Lima, Ana Rita; Carvalho-Maia, Carina; Jerónimo, Carmen; Henrique, Rui; Aveiro, Susana S.; Melo, Tânia; Domingues, Maria Rosário; et al. "Metabolomics and lipidomics approaches reveal new dysregulations associated with prostate cancer". Paper presented in 3rd EpiLipidNET General Action Meeting, 2022.
Journal article
  1. Debora Maffeo; Angela Rina; Viola Bianca Serio; Athina Markou; Tomasz Powrózek; Vera Constâncio; Sandra P. Nunes; et al. "The Evidence Base for Circulating Tumor DNA-Methylation in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis". Cancers (2024): https://doi.org/10.3390/cancers16213641.
    10.3390/cancers16213641
  2. Ana Rodrigues; Rui Henrique; Carmen Jerónimo; António Araújo. "Correction: Management of typical and atypical metastatic lung carcinoids: present and future perspectives". Clinical and Translational Oncology (2024): https://doi.org/10.1007/s12094-024-03738-4.
    10.1007/s12094-024-03738-4
  3. Bárbara Matos; Antoniel A. S. Gomes; Raquel Bernardino; Marco G. Alves; John Howl; Carmen Jerónimo; Margarida Fardilha. "CAVPENET Peptide Inhibits Prostate Cancer Cells Proliferation and Migration through PP1¿-Dependent Inhibition of AKT Signaling". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16091199.
    10.3390/pharmaceutics16091199
  4. Ana Rodrigues; Rui Henrique; Carmen Jerónimo; António Araújo. "Management of typical and atypical metastatic lung carcinoids: present and future perspectives". Clinical and Translational Oncology (2024): https://doi.org/10.1007/s12094-024-03607-0.
    10.1007/s12094-024-03607-0
  5. Sofia Salta; José Pedro Sequeira; João Lobo; Ana Sousa; Hugo Sousa; Inês Baldaque; Paula Monteiro; et al. "Preliminary outcomes of the Cervical Cancer Screening Program of Northern Portugal: A snapshot". Journal of Infection and Public Health (2024): https://doi.org/10.1016/j.jiph.2024.04.020.
    10.1016/j.jiph.2024.04.020
  6. Silva-Ferreira, Mariana; Carvalho, João A.; Salta, Sofia; Henriques, Teresa S.; Pereira Rodrigues, Pedro; Monteiro-Reis, Sara; Henrique, Rui; Jerónimo, Carmen. "Diagnostic Test Accuracy of Urinary DNA Methylation-based Biomarkers for the Detection of Primary and Recurrent Bladder Cancer: A Systematic Review and Meta-analysis". European Urology Focus (2024): http://dx.doi.org/10.1016/j.euf.2024.05.024.
    Accepted • 10.1016/j.euf.2024.05.024
  7. José Pedro Sequeira; Sofia Salta; Rui Freitas; Rafael López-López; Ángel Díaz-Lagares; Rui Henrique; Carmen Jerónimo. "Biomarkers for Pre-Treatment Risk Stratification of Prostate Cancer Patients: A Systematic Review". Cancers (2024): https://doi.org/10.3390/cancers16071363.
    10.3390/cancers16071363
  8. Estevão-Pereira, Helena; Guimarães-Teixeira, Catarina; Flores, Bianca C. T.; Moreira-Silva, Filipa; Tavares, Nuno Tiago; Guimarães, Rita; Braga, Isaac; et al. "EHMT2/G9a and EZH2: Epimarkers in testicular germ cell tumors". Andrology (2024): http://dx.doi.org/10.1111/andr.13604.
    10.1111/andr.13604
  9. Eduarda P. Martins; Joana Vieira de Castro; Rita Fontes; Sara Monteiro-Reis; Rui Henrique; Carmen Jerónimo; Bruno M. Costa. "Relevance of HOTAIR rs920778 and rs12826786 Genetic Variants in Bladder Cancer Risk and Survival". Cancers (2024): https://doi.org/10.3390/cancers16020434.
    10.3390/cancers16020434
  10. Nunes, Sandra P.; Morales, Lucia; Rubio, Carolina; Munera-Maravilla, Ester; Lodewijk, Iris; Suárez-Cabrera, Cristian; Martínez, Victor G.; et al. "Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer". Cell Death Discovery 10 1 (2024): http://dx.doi.org/10.1038/s41420-023-01786-3.
    10.1038/s41420-023-01786-3
  11. Mayayo-Peralta, Isabel; Debets, Donna O.; Prekovic, Stefan; Schuurman, Karianne; Beerthuijzen, Suzanne; Almekinders, Mathilde; Sanders, Joyce; et al. "Proteomics on malignant pleural effusions reveals ERalpha loss in metastatic breast cancer associates withSGK1/NDRG1 deregulation". Molecular Oncology 18 1 (2023): 156-169. http://dx.doi.org/10.1002/1878-0261.13540.
    10.1002/1878-0261.13540
  12. Catarina Macedo-Silva; Vera Miranda-Gonçalves; Nuno Tiago Tavares; Daniela Barros-Silva; Joana Lencart; João Lobo; Ângelo Oliveira; et al. "Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling". Signal Transduction and Targeted Therapy (2023): https://doi.org/10.1038/s41392-023-01639-6.
    10.1038/s41392-023-01639-6
  13. Vânia Camilo; Mariana Brütt Pacheco; Filipa Moreira-Silva; Gonçalo Outeiro-Pinho; Vítor M. Gaspar; João F. Mano; C. Joana Marques; Rui Henrique; Carmen Jerónimo. "Novel Insights on the Role of Epigenetics in Androgen Receptor’s Expression in Prostate Cancer". Biomolecules (2023): https://doi.org/10.3390/biom13101526.
    10.3390/biom13101526
  14. Sequeira, José Pedro; Barros-Silva, Daniela; Ferreira-Torre, Patrícia; Salta, Sofia; Braga, Isaac; Carvalho, João; Freitas, Rui; Henrique, Rui; Jerónimo, Carmen. "OncoUroMiR: Circulating miRNAs for Detection and Discrimination of the Main Urological Cancers Using a ddPCR-Based Approach". International Journal of Molecular Sciences 24 18 (2023): 13890. http://dx.doi.org/10.3390/ijms241813890.
    10.3390/ijms241813890
  15. Salta, Sofia; Lobo, João; Magalhães, Bruno; Henrique, Rui; Jerónimo, Carmen. Corresponding author: Jerónimo, Carmen. "DNA methylation as a triage marker for colposcopy referral in HPV-based cervical cancer screening: a systematic review and meta-analysis". Clinical Epigenetics 15 1 (2023): http://dx.doi.org/10.1186/s13148-023-01537-2.
    Published • 10.1186/s13148-023-01537-2
  16. Nuno Tiago Tavares; Rui Henrique; Aditya Bagrodia; Carmen Jerónimo; João Lobo. "A stroll through the present and future of testicular germ cell tumour biomarkers". Expert Review of Molecular Diagnostics (2023): https://doi.org/10.1080/14737159.2023.2206956.
    10.1080/14737159.2023.2206956
  17. Daniela Barros-Silva; Johan Tsui; Carmen Jerónimo; Guido Jenster; Elena S Martens-Uzunova. "Site-specific analysis of ribosomal 2'O-methylation by quantitative reverse transcription PCR under low deoxynucleotide triphosphate concentrations". BioTechniques (2023): https://doi.org/10.2144/btn-2022-0122.
    10.2144/btn-2022-0122
  18. Lobo, João; Tavares, Nuno Tiago; Barros-Silva, Daniela; Rosinha, Alina; Morais, António; Jerónimo, Carmen; Rodrigues, Ângelo; Henrique, Rui. "MiR-371a-3p in cystic trophoblastic tumour of the testis: supporting a maturation phenomenon towards teratoma". Histopathology 83 1 (2023): 151-154. http://dx.doi.org/10.1111/his.14929.
    10.1111/his.14929
  19. dos Reis, FD; Jerónimo, Carmen; Correia, Margareta. Corresponding author: Correia, Margareta. "Epigenetic modulation and prostate cancer: Paving the way for NK cell anti-tumor immunity". Frontiers in Immunology (2023): https://www.frontiersin.org/articles/10.3389/fimmu.2023.1152572/full.
    Published • 10.3389/fimmu.2023.1152572
  20. Ana Teixeira-Marques; Catarina Lourenço; Miguel Carlos Oliveira; Rui Henrique; Carmen Jerónimo. "Extracellular Vesicles as Potential Bladder Cancer Biomarkers: Take It or Leave It?". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24076757.
    10.3390/ijms24076757
  21. Montezuma, Diana; Varelas, Ana Isabel; Leite-Silva, Pedro; Teixeira-Marques, Ana; Monteiro-Reis, Sara; Oliveira, Miguel Carlos; Carvalho, João André; et al. "Impact of Standard Clinicopathologic Parameters in a Contemporary Cohort of Bladder Urothelial Carcinoma With 10 Years of Follow-Up". Human Pathology (2023):
    Submitted
  22. Francisco Conceição; Daniela M. Sousa; Sofia Tojal; Catarina Lourenço; Carina Carvalho-Maia; Helena Estevão-Pereira; João Lobo; et al. "The Secretome of Parental and Bone Metastatic Breast Cancer Elicits Distinct Effects in Human Osteoclast Activity after Activation of ß2 Adrenergic Signaling". Biomolecules (2023): https://doi.org/10.3390/biom13040622.
    10.3390/biom13040622
  23. Tânia Lima; Catarina Macedo-Silva; Diana Felizardo; João Fraga; Isa Carneiro; Carmen Jerónimo; Rui Henrique; Margarida Fardilha; Rui Vitorino. "Gal-3 Protein Expression and Localization in Prostate Tumours". Current Oncology (2023): https://doi.org/10.3390/curroncol30030206.
    10.3390/curroncol30030206
  24. Nuno Tiago Tavares; Rui Henrique; Carmen Jerónimo; João Lobo. "Targeting histone deacetylases in testicular germ cell tumours: an encouraging treatment approach for the future†". The Journal of Pathology (2023): https://doi.org/10.1002/path.6037.
    10.1002/path.6037
  25. Jan Roška; João Lobo; Danica Ivovic; Lenka Wachsmannová; Thomas Mueller; Rui Henrique; Carmen Jerónimo; Miroslav Chovanec; Dana Jurkovicová. "Integrated Microarray-Based Data Analysis of miRNA Expression Profiles: Identification of Novel Biomarkers of Cisplatin-Resistance in Testicular Germ Cell Tumours". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24032495.
    10.3390/ijms24032495
  26. Macedo-Silva, Catarina; Constâncio, Vera; Miranda-Gonçalves, Vera; Leite-Silva, Pedro; Salta, Sofia; Lobo, João; Guimarães, Rita; et al. "DNA methylation biomarkers accurately detect esophageal cancer prior and post neoadjuvant chemoradiation". Cancer Medicine 12 7 (2023): 8777-8788. http://dx.doi.org/10.1002/cam4.5623.
    10.1002/cam4.5623
  27. Martins-Lima, Cláudia; Chianese, Ugo; Benedetti, Rosaria; Altucci, Lucia; Jerónimo, Carmen; Correia, Margareta P.. Corresponding author: Correia, Margareta P.. "Tumor microenvironment and epithelial-mesenchymal transition in bladder cancer: Cytokines in the game?". Frontiers in Molecular Biosciences 9 (2023): http://dx.doi.org/10.3389/fmolb.2022.1070383.
    10.3389/fmolb.2022.1070383
  28. Sara Monteiro-Reis; João P. S. Ferreira; Ricardo A. Pires; João Lobo; João A. Carvalho; Rui L. Reis; Renato Natal Jorge; Carmen Jerónimo. "Bladder Wall Stiffness after Cystectomy in Bladder Cancer Patients: A Preliminary Study". Cancers (2023): https://doi.org/10.3390/cancers15020359.
    10.3390/cancers15020359
  29. Monteiro-Reis, Sara; Miranda-Gonçalves, Vera; Guimarães-Teixeira, Catarina; Martins-Lima, Cláudia; Lobo, João; Montezuma, Diana; Dias, Paula C.; et al. "Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition". International Journal of Biological Sciences 19 1 (2023): 1-12. http://dx.doi.org/10.7150/ijbs.77181.
    Published • 10.7150/ijbs.77181
  30. Anabela Couto-Cunha; Carmen Jerónimo; Rui Henrique. "Circulating Tumor Cells as Biomarkers for Renal Cell Carcinoma: Ready for Prime Time?". Cancers (2022): https://doi.org/10.3390/cancers15010287.
    10.3390/cancers15010287
  31. Inês Direito; Daniela Gomes; Fátima Liliana Monteiro; Isa Carneiro; João Lobo; Rui Henrique; Carmen Jerónimo; Luisa Alejandra Helguero. "The Clinicopathological Significance of BiP/GRP-78 in Breast Cancer: A Meta-Analysis of Public Datasets and Immunohistochemical Detection". Current Oncology (2022): https://doi.org/10.3390/curroncol29120710.
    10.3390/curroncol29120710
  32. Daniela M. Sousa; Veronica Fernandes; Catarina Lourenço; Carina Carvalho-Maia; Helena Estevão-Pereira; João Lobo; Mariana Cantante; et al. "Profiling the Adrenergic System in Breast Cancer and the Development of Metastasis". Cancers (2022): https://doi.org/10.3390/cancers14225518.
    10.3390/cancers14225518
  33. Outeiro-Pinho, Gonçalo; Barros-Silva, Daniela; Moreira-Silva, Filipa; Lobo, João; Carneiro, Isa; Morais, António; Martins, Eduarda P; et al. "Epigenetically-regulated miR-30a/c-5p directly target TWF1 and hamper ccRCC cell aggressiveness". Translational Research 249 (2022): 110-127. https://www.translationalres.com/article/S1931-5244(22)00141-4/fulltext.
    Published
  34. Vera Constâncio; Nuno Tiago Tavares; Rui Henrique; Carmen Jerónimo; João Lobo. "MiRNA biomarkers in cancers of the male reproductive system: Are we approaching clinical application?". Andrology (2022): https://doi.org/10.1111/andr.13258.
    10.1111/andr.13258
  35. Nuno Tiago Tavares; Saule Gumauskaite; João Lobo; Carmen Jerónimo; Rui Henrique. "DNA Methylation Biomarkers for Prediction of Response to Platinum-Based Chemotherapy: Where Do We Stand?". Cancers 14 12 (2022): 2918-2918. https://doi.org/10.3390/cancers14122918.
    10.3390/cancers14122918
  36. Tânia Lima; António S. Barros; Fábio Trindade; Rita Ferreira; Adelino Leite-Moreira; Daniela Barros-Silva; Carmen Jerónimo; et al. "Application of Proteogenomics to Urine Analysis towards the Identification of Novel Biomarkers of Prostate Cancer: An Exploratory Study". Cancers 14 8 (2022): 2001-2001. https://doi.org/10.3390/cancers14082001.
    10.3390/cancers14082001
  37. Catarina Lourenço; Francisco Conceição; Carmen Jeronimo; Carmen Jerónimo; Meriem Lamghari; Daniela M. Sousa. "Stress in Metastatic Breast Cancer: To the Bone and Beyond". Cancers (2022): https://www.mdpi.com/2072-6694/14/8/1881.
    10.3390/cancers14081881
  38. Beatriz Chaves Lourenço; Catarina Guimarães-Teixeira; Bianca C. T. Flores; Vera Miranda-Gonçalves; Rita Guimarães; Mariana Cantante; Paula Lopes; et al. "Ki67 and LSD1 Expression in Testicular Germ Cell Tumors Is Not Associated with Patient Outcome: Investigation Using a Digital Pathology Algorithm". Life (2022): https://doi.org/10.3390/life12020264.
    10.3390/life12020264
  39. José Pedro Sequeira; Vera Constâncio; Sofia Salta; João Lobo; Daniela Barros-Silva; Carina Carvalho-Maia; Jéssica Rodrigues; et al. "LiKidMiRs: A ddPCR-Based Panel of 4 Circulating miRNAs for Detection of Renal Cell Carcinoma". Cancers (2022): https://doi.org/10.3390/cancers14040858.
    10.3390/cancers14040858
  40. Sara Petronilho; José Pedro Sequeira; Sofia Paulino; Paula Lopes; Susana Lisboa; Sérgio Chacim; João Lobo; et al. "Prognostic Value of Histone Modifying Enzyme EZH2 in RCHOP-Treated Diffuse Large B-Cell Lymphoma and High Grade B-Cell Lymphoma". Journal of Personalized Medicine (2021): https://doi.org/10.3390/jpm11121384.
    10.3390/jpm11121384
  41. João Lobo; Vera Constâncio; Pedro Leite-Silva; Rita Guimarães; Mariana Cantante; Isaac Braga; Joaquina Maurício; et al. "Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples". Clinical Epigenetics (2021): https://doi.org/10.1186/s13148-021-01048-y.
    10.1186/s13148-021-01048-y
  42. Catarina Macedo-Silva; Rosaria Benedetti; Fortunato Ciardiello; Salvatore Cappabianca; Carmen Jerónimo; Lucia Altucci. "Epigenetic mechanisms underlying prostate cancer radioresistance". Clinical Epigenetics (2021): https://doi.org/10.1186/s13148-021-01111-8.
    10.1186/s13148-021-01111-8
  43. Juliana Pedro; Sara Monteiro-Reis; Carina Carvalho-Maia; Rui Henrique; Carmen Jerónimo; Eunice R. Silva. "Evidence of psychological and biological effects of structured Mindfulness-Based Interventions for cancer patients and survivors: A meta-review". Psycho-Oncology 30 11 (2021): 1836-1848. https://doi.org/10.1002/pon.5771.
    10.1002/pon.5771
  44. Sandra M. Rocha; Inês Sousa; Inês M. Gomes; Patrícia Arinto; Pedro Costa-Pinheiro; Eduarda Coutinho; Cecília R. Santos; et al. "Promoter Demethylation Upregulates STEAP1 Gene Expression in Human Prostate Cancer: In Vitro and In Silico Analysis". Life 11 11 (2021): 1251-1251. https://doi.org/10.3390/life11111251.
    10.3390/life11111251
  45. João Lobo; Carmen Jerónimo; Rui Henrique. "Morphological and molecular heterogeneity in testicular germ cell tumors: implications for dedicated investigations". Virchows Archiv (2021): https://doi.org/10.1007/s00428-021-03194-3.
    10.1007/s00428-021-03194-3
  46. José Pedro Sequeira; Vera Constâncio; João Lobo; Rui Henrique; Carmen Jerónimo. "Unveiling the World of Circulating and Exosomal microRNAs in Renal Cell Carcinoma". Cancers 13 21 (2021): 5252-5252. https://doi.org/10.3390/cancers13215252.
    10.3390/cancers13215252
  47. Daniela Barros-Silva; Jonathan Klavert; Guido Jenster; Carmen Jerónimo; Denis L.J. Lafontaine; Elena S. Martens-Uzunova. "The role of OncoSnoRNAs and Ribosomal RNA 2'-O-methylation in Cancer". RNA Biology 18 sup1 (2021): 61-74. https://doi.org/10.1080/15476286.2021.1991167.
    10.1080/15476286.2021.1991167
  48. Diana Montezuma; Ana Teixeira-Marques; Carmen Jerónimo; Rui Henrique. "Epigenetic extracellular vesicle-based biomarkers for urological malignancies: is the hope worth the hype?". Epigenomics 13 19 (2021): 1514-1521. https://doi.org/10.2217/epi-2021-0333.
    10.2217/epi-2021-0333
  49. Catarina Guimarães-Teixeira; Daniela Barros Silva; João Lobo; Diana Soares-Fernandes; Vera Constâncio; Pedro Leite-Silva; Rui Silva-Santos; et al. "Deregulation of N6-Methyladenosine RNA Modification and Its Erasers FTO/ALKBH5 among the Main Renal Cell Tumor Subtypes". Journal of Personalized Medicine (2021): https://www.mdpi.com/2075-4426/11/10/996.
    10.3390/jpm11100996
  50. Bianca C. T. Flores; Margareta P. Correia; José G. Rodríguez; Rui Henrique; Carmen Jerónimo. "Bridging the Gaps between Circulating Tumor Cells and DNA Methylation in Prostate Cancer". Cancers (2021): https://doi.org/10.3390/cancers13164209.
    10.3390/cancers13164209
  51. Nair Lopes; Mariana Brütt Pacheco; Diana Soares-Fernandes; Margareta P. Correia; Vânia Camilo; Rui Henrique; Carmen Jerónimo. "Hydralazine and Enzalutamide: Synergistic Partners against Prostate Cancer". Biomedicines 9 8 (2021): 976-976. https://doi.org/10.3390/biomedicines9080976.
    10.3390/biomedicines9080976
  52. Mariana Brütt Pacheco; Vânia Camilo; Nair Lopes; Filipa Moreira-Silva; Margareta P. Correia; Rui Henrique; Carmen Jerónimo. "Hydralazine and Panobinostat Attenuate Malignant Properties of Prostate Cancer Cell Lines". Pharmaceuticals 14 7 (2021): 670-670. https://doi.org/10.3390/ph14070670.
    10.3390/ph14070670
  53. Diana Gulei; Alice Indini; Carmen Jerónimo; Cristina-Adela Iuga; Francesco Grossi. "Cancer Mechanisms and Emerging Therapies". Pharmaceutics 13 7 (2021): 1045-1045. https://doi.org/10.3390/pharmaceutics13071045.
    10.3390/pharmaceutics13071045
  54. Inês Direito; Liliana Monteiro; Tânia Melo; Daniela Figueira; João Lobo; Vera Enes; Gabriela Moura; et al. "Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance". Cancers 13 13 (2021): 3195-3195. https://doi.org/10.3390/cancers13133195.
    10.3390/cancers13133195
  55. Mariana Brütt Pacheco; Vânia Camilo; Rui Henrique; Carmen Jerónimo. "Epigenetic Editing in Prostate Cancer: Challenges and Opportunities". Epigenetics (2021): https://doi.org/10.1080/15592294.2021.1939477.
    10.1080/15592294.2021.1939477
  56. Anna Adam-Artigues; Iris Garrido-Cano; J.A. Carbonell-Asins; Ana Lameirinhas; Soraya Simón; Belén Ortega-Morillo; María Teresa Martínez; et al. "Identification of a Two-MicroRNA Signature in Plasma as a Novel Biomarker for Very Early Diagnosis of Breast Cancer". Cancers (2021): https://www.mdpi.com/2072-6694/13/11/2848.
    10.3390/cancers13112848
  57. Ângela Carvalho; Gabriela Ferreira; Duarte Seixas; Catarina Guimarães-Teixeira; Rui Henrique; Fernando J. Monteiro; Carmen Jerónimo. "Emerging Lab-on-a-Chip Approaches for Liquid Biopsy in Lung Cancer: Status in CTCs and ctDNA Research and Clinical Validation". Cancers (2021): https://doi.org/10.3390/cancers13092101.
    10.3390/cancers13092101
  58. Catarina Lourenço; Vera Constâncio; Rui Henrique; Ângela Carvalho; Carmen Jerónimo. "Urinary Extracellular Vesicles as Potential Biomarkers for Urologic Cancers: An Overview of Current Methods and Advances". Cancers 13 7 (2021): 1529-1529. https://doi.org/10.3390/cancers13071529.
    10.3390/cancers13071529
  59. Joana Pinto; Ângela Carapito; Filipa Amaro; Ana Rita Lima; Carina Carvalho-Maia; Maria Conceição Martins; Carmen Jerónimo; et al. "Discovery of Volatile Biomarkers for Bladder Cancer Detection and Staging through Urine Metabolomics". Metabolites 11 4 (2021): 199-199. https://doi.org/10.3390/metabo11040199.
    10.3390/metabo11040199
  60. Sara Monteiro-Reis; Carina Carvalho-Maia; Genevieve Bart; Seppo J. Vainio; Juliana Pedro; Eunice R. Silva; Goreti Sales; Rui Henrique; Carmen Jerónimo. "Secreted Extracellular Vesicle Molecular Cargo as a Novel Liquid Biopsy Diagnostics of Central Nervous System Diseases". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms22063267.
    10.3390/ijms22063267
  61. João Lobo; Ricardo Leão; Carmen Jerónimo; Rui Henrique. "Liquid Biopsies in the Clinical Management of Germ Cell Tumor Patients: State-of-the-Art and Future Directions". International Journal of Molecular Sciences 22 5 (2021): 2654-2654. https://doi.org/10.3390/ijms22052654.
    10.3390/ijms22052654
  62. João Lobo; Ana Rita Cardoso; Vera Miranda-Gonçalves; Leendert H. J. Looijenga; Marie Lopez; Paola B. Arimondo; Rui Henrique; Carmen Jerónimo. "Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest". Pharmaceutics (2021): https://doi.org/10.3390/pharmaceutics13010073.
    10.3390/pharmaceutics13010073
  63. Filipa Quintela Vieira; Ângela Marques-Magalhães; Vera Miranda-Gonçalves; Ricardo Ferraz; Mónica Vieira; Cristina Prudêncio; Carmen Jerónimo; Regina Augusta Silva. "The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines". International Journal of Molecular Sciences 21 24 (2020): 9584-9584. https://doi.org/10.3390/ijms21249584.
    10.3390/ijms21249584
  64. Macedo-Silva, Catarina; Miranda-Gonçalves, Vera; Lameirinhas, Ana; Lencart, Joana; Pereira, Alexandre; Lobo, João; Guimarães, Rita; et al. "JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma". Cell Death & Disease 11 12 (2020): http://dx.doi.org/10.1038/s41419-020-03279-y.
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  65. Mário Fontes-Sousa; João Lobo; Silvana Lobo; Sofia Salta; Maria Amorim; Paula Lopes; Luís Antunes; et al. "Digital imaging-assisted quantification of H3K27me3 immunoexpression in luminal A/B-like, HER2-negative, invasive breast cancer predicts patient survival and risk of recurrence". Molecular Medicine 26 1 (2020): https://doi.org/10.1186/s10020-020-0147-5.
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  66. João Lobo; Sara Monteiro-Reis; Catarina Guimarães-Teixeira; Paula Lopes; Isa Carneiro; Carmen Jerónimo; Rui Henrique. "Practicability of clinical application of bladder cancer molecular classification and additional value of epithelial-to-mesenchymal transition: prognostic value of vimentin expression". Journal of Translational Medicine (2020): https://doi.org/10.1186/s12967-020-02475-w.
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  67. Rita Silva-Oliveira; Filipa Ferreira Pereira; Sara Petronilho; Ana Teresa Martins; Ana Lameirinhas; Vera Constâncio; Inês Ribeiro; et al. "Clinical Significance of ARID1A and ANXA1 in HER-2 Positive Breast Cancer". Journal of Clinical Medicine (2020): https://www.mdpi.com/2077-0383/9/12/3911.
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  68. Manuela Costantini; Carla Azzurra Amoreo; Liborio Torregrossa; Greta Alì; Enrico Munari; Carmen Jeronimo; Rui Henrique; et al. "Assessment of HER2 Protein Overexpression and Gene Amplification in Renal Collecting Duct Carcinoma: Therapeutic Implication". Cancers 12 11 (2020): 3345-3345. https://doi.org/10.3390/cancers12113345.
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  69. Md Ismail Hosen; Nathalie Forey; Geoffroy Durand; Catherine Voegele; Selin Bilici; Patrice Hodonou Avogbe; Tiffany M. Delhomme; et al. "Development of Sensitive Droplet Digital PCR Assays for Detecting Urinary TERT Promoter Mutations as Non-Invasive Biomarkers for Detection of Urothelial Cancer". Cancers (2020): https://www.mdpi.com/2072-6694/12/12/3541.
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  70. Iris Garrido-Cano; Vera Constâncio; Anna Adam-Artigues; Ana Lameirinhas; Soraya Simón; Belen Ortega; María Teresa Martínez; et al. "Circulating miR-99a-5p Expression in Plasma: A Potential Biomarker for Early Diagnosis of Breast Cancer". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/21/19/7427.
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  71. João Lobo; Maria Ana Alzamora; Rita Guimarães; Mariana Cantante; Paula Lopes; Isaac Braga; Joaquina Maurício; Carmen Jerónimo; Rui Henrique. "p53 and MDM2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome". Andrology 8 5 (2020): 1233-1242. https://doi.org/10.1111/andr.12814.
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  72. João Lobo; Rita Guimarães; Vera Miranda-Gonçalves; Sara Monteiro-Reis; Mariana Cantante; Luís Antunes; Isaac Braga; et al. "Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes". Epigenomics (2020): https://doi.org/10.2217/epi-2020-0066.
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  73. Ana Rita Cardoso; João Lobo; Vera Miranda-Gonçalves; Rui Henrique; Carmen Jerónimo. "Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of ‘epidrugs’". Epigenetics (2020): https://doi.org/10.1080/15592294.2020.1805682.
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  74. Sandra P. Nunes; Rui Henrique; Carmen Jerónimo; Jesús M. Paramio. "DNA Methylation as a Therapeutic Target for Bladder Cancer". Cells (2020): https://doi.org/10.3390/cells9081850.
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  75. Gonçalo Outeiro-Pinho; Daniela Barros-Silva; Margareta P. Correia; Rui Henrique; Carmen Jerónimo. "Renal Cell Tumors: Uncovering the Biomarker Potential of ncRNAs". Cancers 12 8 (2020): 2214-2214. https://doi.org/10.3390/cancers12082214.
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  76. Ana Rita Lima; Joana Pinto; Carina Carvalho-Maia; Carmen Jerónimo; Rui Henrique; Maria de Lourdes Bastos; Márcia Carvalho; Paula Guedes de Pinho. "A Panel of Urinary Volatile Biomarkers for Differential Diagnosis of Prostate Cancer from Other Urological Cancers". Cancers 12 8 (2020): 2017-2017. https://doi.org/10.3390/cancers12082017.
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  77. João Lobo; Carmen Jerónimo; Rui Henrique. "Cisplatin Resistance in Testicular Germ Cell Tumors: Current Challenges from Various Perspectives". Cancers (2020): https://doi.org/10.3390/cancers12061601.
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  78. Ana Rita Lima; Joana Pinto; Daniela Barros-Silva; Carmen Jerónimo; Rui Henrique; Maria de Lourdes Bastos; Márcia Carvalho; Paula Guedes Pinho. "New findings on urinary prostate cancer metabolome through combined GC–MS and 1H NMR analytical platforms". Metabolomics 16 6 (2020): https://doi.org/10.1007/s11306-020-01691-1.
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  79. Nair Lopes; Margareta P. Correia; Rui Henrique; Carmen Jerónimo. "Epigenetic Alterations in Oesophageal Cancer: Expression and Role of the Involved Enzymes". International Journal of Molecular Sciences 21 10 (2020): 3522-3522. https://doi.org/10.3390/ijms21103522.
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  80. Vera Miranda-Gonçalves; Ana Lameirinhas; Rui Henrique; Fátima Baltazar; Carmen Jerónimo. "The metabolic landscape of urological cancers: New therapeutic perspectives". Cancer Letters 477 (2020): 76-87. https://doi.org/10.1016/j.canlet.2020.02.034.
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  81. Filipa Moreira-Silva; Vânia Camilo; Vítor Gaspar; João F. Mano; Rui Henrique; Carmen Jerónimo. "Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?". Pharmaceutics 12 5 (2020): 410-410. https://doi.org/10.3390/pharmaceutics12050410.
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  82. Filipa Amaro; Joana Pinto; Sílvia Rocha; Ana Margarida Araújo; Vera Miranda-Gonçalves; Carmen Jerónimo; Rui Henrique; et al. "Volatilomics Reveals Potential Biomarkers for Identification of Renal Cell Carcinoma: An In Vitro Approach". Metabolites 10 5 (2020): 174-174. https://doi.org/10.3390/metabo10050174.
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  83. Vera Miranda-Gonçalves; Ana Lameirinhas; Catarina Macedo-Silva; João Lobo; Paula C. Dias; Verónica Ferreira; Rui Henrique; Carmen Jerónimo. "Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation". Cells (2020): https://doi.org/10.3390/cells9041053.
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  84. Saudade André; Sandra P. Nunes; Fernanda Silva; Rui Henrique; Ana Félix; Carmen Jerónimo. "Analysis of Epigenetic Alterations in Homologous Recombination DNA Repair Genes in Male Breast Cancer". International Journal of Molecular Sciences 21 8 (2020): 2715-2715. https://doi.org/10.3390/ijms21082715.
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  85. Jerónimo, Carmen. "The inflammation-related biomarker CXCR7 independently predicts patient outcome after radical prostatectomy.". Urologic oncology (2020): https://doi.org/10.1016/j.urolonc.2020.03.004.
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  86. Jerónimo, Carmen. "RAD51Bme Levels as a Potential Predictive Biomarker for PD-1 Blockade Response in Non-Small Cell Lung Cancer.". Journal of clinical medicine (2020): https://doi.org/10.3390/jcm9041000.
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  87. Sara Monteiro-Reis; Ana Lameirinhas; Vera Miranda-Gonçalves; Diana Montezuma; Paula C. Dias; Jorge Oliveira; Inês Graça; et al. "Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion". Cancers (2020): https://www.mdpi.com/2072-6694/12/5/1066.
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  88. Daniela Barros-Silva; João Lobo; Catarina Guimarães-Teixeira; Isa Carneiro; Jorge Oliveira; Elena S. Martens-Uzunova; Rui Henrique; Carmen Jerónimo. "VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer". Cancers 12 4 (2020): 771-771. https://doi.org/10.3390/cancers12040771.
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  89. Vera Constâncio; Sandra P. Nunes; Rui Henrique; Carmen Jerónimo. "DNA Methylation-Based Testing in Liquid Biopsies as Detection and Prognostic Biomarkers for the Four Major Cancer Types". Cells (2020): https://doi.org/10.3390/cells9030624.
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  90. Sara Monteiro-Reis; Ana Blanca; Joana Tedim-Moreira; Isa Carneiro; Diana Montezuma; Paula Monteiro; Jorge Oliveira; et al. "A Multiplex Test Assessing MiR663ame and VIMme in Urine Accurately Discriminates Bladder Cancer from Inflammatory Conditions". Journal of Clinical Medicine (2020): https://www.mdpi.com/2077-0383/9/2/605.
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  91. João Lobo; Carmen Jerónimo; Rui Henrique. "Targeting the Immune system and Epigenetic Landscape of Urological Tumors". International Journal of Molecular Sciences 21 3 (2020): 829-829. https://doi.org/10.3390/ijms21030829.
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  92. Jerónimo, Carmen. "Overexpression of circulating MiR-30b-5p identifies advanced breast cancer.". Journal of translational medicine (2019): https://europepmc.org/articles/PMC6936051.
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  93. João Lobo; Ad J.M. Gillis; Annette van den Berg; Lambert C.J. Dorssers; Gazanfer Belge; Klaus-Peter Dieckmann; Henk P. Roest; et al. "Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data". Cells (2019): https://www.mdpi.com/2073-4409/8/12/1637.
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  94. Catarina Macedo-Silva; Vera Miranda-Gonçalves; Rui Henrique; Carmen Jerónimo; Isabel Bravo. "The Critical Role of Hypoxic Microenvironment and Epigenetic Deregulation in Esophageal Cancer Radioresistance". Genes 10 11 (2019): 927-927. https://doi.org/10.3390/genes10110927.
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  95. João Lobo; Carla Pinto; Manuela Pinheiro; Francisco Lobo; Nuno Sousa; Paula Lopes; Leendert HJ Looijenga; et al. "Widening the spectrum of Lynch syndrome: first report of testicular seminoma attributable to MSH2 loss". Histopathology (2019): https://doi.org/10.1111/his.13979.
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  96. João Lobo; Ângelo Rodrigues; Rita Guimarães; Mariana Cantante; Paula Lopes; Joaquina Maurício; Jorge Oliveira; Carmen Jerónimo; Rui Henrique. "Detailed Characterization of Immune Cell Infiltrate and Expression of Immune Checkpoint Molecules PD-L1/CTLA-4 and MMR Proteins in Testicular Germ Cell Tumors Disclose Novel Disease Biomarkers". Cancers (2019): https://doi.org/10.3390/cancers11101535.
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  97. Ana Rita Lima; Joana Pinto; Ana Isabel Azevedo; Daniela Barros-Silva; Carmen Jerónimo; Rui Henrique; Maria de Lourdes Bastos; Paula Guedes de Pinho; Márcia Carvalho. "Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urine". British Journal of Cancer (2019): https://doi.org/10.1038/s41416-019-0585-4.
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  98. Vera Constâncio; Daniela Barros-Silva; Carmen Jerónimo; Rui Henrique. "Known epigenetic biomarkers for prostate cancer detection and management: exploring the potential of blood-based liquid biopsies". Expert Review of Molecular Diagnostics (2019): 1-9. https://doi.org/10.1080/14737159.2019.1604224.
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  99. Ana Lameirinhas; Vera Miranda-Gonçalves; Rui Henrique; Carmen Jerónimo. "The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell Carcinoma". Genes (2019): https://doi.org/10.3390/genes10040264.
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  100. Sara Monteiro-Reis; João Lobo; Rui Henrique; Carmen Jerónimo. "Epigenetic Mechanisms Influencing Epithelial to Mesenchymal Transition in Bladder Cancer". International Journal of Molecular Sciences 20 2 (2019): 297-297. https://doi.org/10.3390/ijms20020297.
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  101. João Lobo; Ad J. M. Gillis; Carmen Jeronimo; Rui Henrique; Leendert Looijenga. "Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic". International Journal of Molecular Sciences (2019): http://www.mdpi.com/1422-0067/20/2/258.
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  102. Daniela Rodrigues; Joana Pinto; Ana Margarida Araújo; Carmen Jeronimo; Rui Henrique; Maria de Lourdes Bastos; Guedes de Pinho P.; Carvalho M. "GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells". Metabolites (2019): http://www.mdpi.com/2218-1989/9/1/18.
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  103. Ganesan, A.; Arimondo, P.B.; Rots, M.G.; Jeronimo, C.; Berdasco, M.. "The timeline of epigenetic drug discovery: From reality to dreams". Clinical Epigenetics 11 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076064024&partnerID=MN8TOARS.
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  104. Avogbe, P.H.; Manel, A.; Vian, E.; Durand, G.; Forey, N.; Voegele, C.; Zvereva, M.; et al. "Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer". EBioMedicine 44 (2019): 431-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067818432&partnerID=MN8TOARS.
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  105. Amorim, M.; Lobo, J.; Fontes-Sousa, M.; Estevão-Pereira, H.; Salta, S.; Lopes, P.; Coimbra, N.; et al. "Predictive and Prognostic Value of Selected MicroRNAs in Luminal Breast Cancer". Frontiers in Genetics 10 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072836043&partnerID=MN8TOARS.
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  108. Carneiro, I.; Quintela-Vieira, F.; Lobo, J.; Moreira-Barbosa, C.; Menezes, F.D.; Martins, A.T.; Oliveira, J.; et al. "Expression of EMT-related genes CAMK2N1 and WNT5A is increased in locally invasive and metastatic prostate cancer". Journal of Cancer 10 24 (2019): 5915-5925. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075870270&partnerID=MN8TOARS.
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  114. Antunes, J.; Gaspar, V.M.; Ferreira, L.; Monteiro, M.; Henrique, R.; Jerónimo, C.; Mano, J.F.. "In-air production of 3D co-culture tumor spheroid hydrogels for expedited drug screening". Acta Biomaterialia 94 (2019): 392-409. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067296733&partnerID=MN8TOARS.
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  115. João Lobo; Rui Henrique; Carmen Jerónimo. "The Role of DNA/Histone Modifying Enzymes and Chromatin Remodeling Complexes in Testicular Germ Cell Tumors". Cancers (2018): https://doi.org/10.3390/cancers11010006.
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  116. Catarina Moreira-Barbosa; Daniela Barros-Silva; Pedro Costa-Pinheiro; Jorge Torres-Ferreira; Vera Constâncio; Rui Freitas; Jorge Oliveira; et al. "Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients". Clinical Epigenetics (2018): https://doi.org/10.1186/s13148-018-0564-2.
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  117. Ana Rita Lima; Ana Margarida Araújo; Joana Pinto; Carmen Jerónimo; Rui Henrique; Maria de Lourdes Bastos; Márcia Carvalho; Paula Guedes de Pinho. "Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-23847-9.
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  118. João Lobo; Daniela Barros-Silva; Rui Henrique; Carmen Jerónimo. "The Emerging Role of Epitranscriptomics in Cancer: Focus on Urological Tumors". Genes 9 11 (2018): 552-552. https://doi.org/10.3390/genes9110552.
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  119. Sofia Salta; Sandra Nunes; Mário Fontes-Sousa; Paula Lopes; Micaela Freitas; Margarida Caldas; Luís Antunes; et al. "A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA". Journal of Clinical Medicine (2018): http://www.mdpi.com/2077-0383/7/11/420.
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  121. Daniela Barros Silva; C. Joana Marques; Rui Henrique; Carmen Jeronimo. "Profiling DNA Methylation Based on Next-Generation Sequencing Approaches: New Insights and Clinical Applications". Genes (2018): http://www.mdpi.com/2073-4425/9/9/429.
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  245. Henrique, R.M.F.; Costa, V.L.; Jerónimo, C.. "Methylation-based biomarkers for early detection of urological cancer". Critical Reviews in Oncogenesis 13 4 (2007): 265-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-43249124527&partnerID=MN8TOARS.
    10.1615/CritRevOncog.v13.i4.10
  246. Nayak, C.S.; Carvalho, A.L.; Jeronimo, C.; Henrique, R.; Kim, M.M.; Hoque, M.O.; Chang, S.; et al. "Positive correlation of tissue inhibitor of metalloproteinase-3 and death-associated protein kinase hypermethylation in head and neck squamous cell carcinoma". Laryngoscope 117 8 (2007): 1376-1380. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548449339&partnerID=MN8TOARS.
    10.1097/MLG.0b013e31806865a8
  247. Henrique, R.; Ribeiro, F.R.; Fonseca, D.; Hoque, M.O.; Carvalho, A.L.; Costa, V.L.; Pinto, M.; et al. "High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients". Clinical Cancer Research 13 20 (2007): 6122-6129. http://www.scopus.com/inward/record.url?eid=2-s2.0-35948929442&partnerID=MN8TOARS.
    10.1158/1078-0432.CCR-07-1042
  248. Henrique, R.M.F.. "New doctorial cancer research: Epigenetic heterogeneity in prostate cancer: Impact of genetic and epigenetic alterations on diagnosis and prognosis". Critical Reviews in Oncogenesis 13 2 (2007): 181-182. http://www.scopus.com/inward/record.url?eid=2-s2.0-37249014413&partnerID=MN8TOARS.
  249. Ribeiro, F.R.; Henrique, R.; Hektoen, M.; Berg, M.; Jerónimo, C.; Teixeira, M.R.; Lothe, R.A.. "Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas". Molecular Cancer 5 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33748968523&partnerID=MN8TOARS.
    10.1186/1476-4598-5-33
  250. Hoque, M.O.; Feng, Q.; Toure, P.; Dem, A.; Critchlow, C.W.; Hawes, S.E.; Wood, T.; et al. "Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer". Journal of Clinical Oncology 24 26 (2006): 4262-4269. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749024160&partnerID=MN8TOARS.
    10.1200/JCO.2005.01.3516
  251. Ribeiro, F.R.; Diep, C.B.; Jerónimo, C.; Henrique, R.; Lopes, C.; Eknæs, M.; Lingjærde, O.C.; Lothe, R.A.; Teixeira, M.R.. "Statistical dissection of genetic pathways involved in prostate carcinogenesis". Genes Chromosomes and Cancer 45 2 (2006): 154-163. http://www.scopus.com/inward/record.url?eid=2-s2.0-31944449020&partnerID=MN8TOARS.
    10.1002/gcc.20279
  252. Ribeiro, F.R.; Jerónimo, C.; Henrique, R.; Fonseca, D.; Oliveira, J.; Lothe, R.A.; Teixeira, M.R.. "8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects". Clinical Cancer Research 12 13 (2006): 3961-3970. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746055324&partnerID=MN8TOARS.
    10.1158/1078-0432.CCR-05-1977
  253. Cerveira, N.; Ribeiro, F.R.; Peixoto, A.; Costa, V.; Henrique, R.; Jerónimo, C.; Teixeira, M.R.. "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions". Neoplasia 8 10 (2006): 826-832. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749870551&partnerID=MN8TOARS.
    10.1593/neo.06427
  254. Henrique, R.; Costa, V.L.; Cerveira, N.; Carvalho, A.L.; Hoque, M.O.; Ribeiro, F.R.; Oliveira, J.; et al. "Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer". Journal of Molecular Medicine 84 11 (2006): 911-918. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750435596&partnerID=MN8TOARS.
    10.1007/s00109-006-0099-4
  255. Pinto, C.; Veiga, I.; Pinheiro, M.; Mesquita, B.; Jerónimo, C.; Sousa, O.; Fragoso, M.; et al. "MSH6 germline mutations in early-onset colorectal cancer patients without family history of the disease". British Journal of Cancer 95 6 (2006): 752-756. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748565629&partnerID=MN8TOARS.
    10.1038/sj.bjc.6603318
  256. Carvalho, A.L.; Chuang, A.; Jiang, W.-W.; Lee, J.; Begum, S.; Poeta, L.; Zhao, M.; et al. "Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma". Cancer Research 66 19 (2006): 9401-9407. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750363705&partnerID=MN8TOARS.
    10.1158/0008-5472.CAN-06-1073
  257. Henrique, R.; Jerónimo, C.; Teixeira, M.R.; Hoque, M.O.; Carvalho, A.L.; Pais, I.; Ribeiro, F.R.; et al. "Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: Clues for clonal progression in prostate carcinogenesis". Molecular Cancer Research 4 1 (2006): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-32944480348&partnerID=MN8TOARS.
    10.1158/1541-7786.MCR-05-0113
  258. Henrique, R.; Jerónimo, C.; Hoque, M.O.; Carvalho, A.L.; Oliveira, J.; Teixeira, M.R.; Lopes, C.; Sidransky, D.. "Frequent 14-3-3s promoter methylation in benign and malignant prostate lesions". DNA and Cell Biology 24 4 (2005): 264-269. http://www.scopus.com/inward/record.url?eid=2-s2.0-16844374138&partnerID=MN8TOARS.
    10.1089/dna.2005.24.264
  259. Jerónimo, C.. "Quantitative methylation profiling of renal tumors and the discovery of a new generation of molecular markers". Future Oncology 1 2 (2005): 197-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646439763&partnerID=MN8TOARS.
    10.1517/14796694.1.2.197
  260. Paredes, J.; Albergaria, A.; Oliveira, J.T.; Jeronimo, C.; Milanezi, F.; Schmitt, F.C.. "P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation". Clinical Cancer Research 11 16 (2005): 5869-5877. http://www.scopus.com/inward/record.url?eid=2-s2.0-23844489449&partnerID=MN8TOARS.
    10.1158/1078-0432.CCR-05-0059
  261. Henrique, R.; Jerónimo, C.; Hoque, M.O.; Nomoto, S.; Carvalho, A.L.; Costa, V.L.; Oliveira, J.; et al. "MT1G hypermethylation is associated with higher tumor stage in prostate cancer". Cancer Epidemiology Biomarkers and Prevention 14 5 (2005): 1274-1278. http://www.scopus.com/inward/record.url?eid=2-s2.0-20844459807&partnerID=MN8TOARS.
    10.1158/1055-9965.EPI-04-0659
  262. Hoque, M.O.; Topaloglu, O.; Begum, S.; Henrique, R.; Rosenbaum, E.; Van Criekinge, W.; Westra, W.H.; Sidransky, D.. "Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects". Journal of Clinical Oncology 23 27 (2005): 6569-6575. http://www.scopus.com/inward/record.url?eid=2-s2.0-27244450828&partnerID=MN8TOARS.
    10.1200/JCO.2005.07.009
  263. Jerónimo, C.; Henrique, R.; Hoque, M.O.; Ribeiro, F.R.; Oliveira, J.; Fonseca, D.; Teixeira, M.R.; Lopes, C.; Sidransky, D.. "Quantitative RARß2 hypermethylation: A promising prostate cancer marker". Clinical Cancer Research 10 12 I (2004): 4010-4014. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042619078&partnerID=MN8TOARS.
    10.1158/1078-0432.CCR-03-0643
  264. Reesink-Peters, N.; Wisman, G.B.A.; Jéronimo, C.; Tokumaru, C.Y.; Cohen, Y.; Dong, S.M.; Klip, H.G.; et al. "Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: A feasibility study". Molecular Cancer Research 2 5 (2004): 289-295. http://www.scopus.com/inward/record.url?eid=2-s2.0-3543067045&partnerID=MN8TOARS.
  265. Hoque, M.O.; Begum, S.; Topaloglu, O.; Jeronimo, C.; Mambo, E.; Westra, W.H.; Califano, J.A.; Sidransky, D.. "Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer". Cancer Research 64 15 (2004): 5511-5517. http://www.scopus.com/inward/record.url?eid=2-s2.0-3442894720&partnerID=MN8TOARS.
    10.1158/0008-5472.CAN-04-0799
  266. Jerónimo, C.; Henrique, R.; Oliveira, J.; Lobo, F.; Pais, I.; Teixeira, M.R.; Lopes, C.. "Aberrant cellular retinol binding protein 1 (CRBP1) gene expression and promoter methylation in prostate cancer". Journal of Clinical Pathology 57 8 (2004): 872-876. http://www.scopus.com/inward/record.url?eid=2-s2.0-4043078431&partnerID=MN8TOARS.
    10.1136/jcp.2003.014555
  267. Henrique, R.; Jerónimo, C.. "Molecular detection of prostate cancer: A role for GSTP1 hypermethylation". European Urology 46 5 (2004): 660-669. http://www.scopus.com/inward/record.url?eid=2-s2.0-5144220196&partnerID=MN8TOARS.
    10.1016/j.eururo.2004.06.014
  268. Jerónimo, C.; Henrique, R.; Hoque, M.O.; Mambo, E.; Ribeiro, F.R.; Varzim, G.; Oliveira, J.; et al. "A quantitative promoter methylation profile of prostate cancer". Clinical Cancer Research 10 24 (2004): 8472-8478. http://www.scopus.com/inward/record.url?eid=2-s2.0-19944429845&partnerID=MN8TOARS.
    10.1158/1078-0432.CCR-04-0894
  269. Begum, S.; Rosenbaum, E.; Henrique, R.; Cohen, Y.; Sidransky, D.; Westra, W.H.. "BRAF mutations in anaplastic thyroid carcinoma: Implications for tumor origin, diagnosis and treatment". Modern Pathology 17 11 (2004): 1359-1363. http://www.scopus.com/inward/record.url?eid=2-s2.0-8144230516&partnerID=MN8TOARS.
    10.1038/modpathol.3800198
  270. Cerveira, N.; Torres, L.; Rocha, P.; Bizarro, S.; Pereira, D.; Abreu, J.; Henrique, R.; Teixeira, M.R.; Castedo, S.. "Highly sensitive detection of the MGB1 transcript (mammaglobin) in the peripheral blood of breast cancer patients". International Journal of Cancer 108 4 (2004): 592-595. http://www.scopus.com/inward/record.url?eid=2-s2.0-0348048477&partnerID=MN8TOARS.
    10.1002/ijc.11609
  271. Cherdwongchareonsuk, D.; Águas, A.P.; Henrique, R.; Upatham, S.; Pereira, A.S.. "Toxic effects of selenium inhalation: Acute damage of the respiratory system of mice". Human and Experimental Toxicology 22 10 (2003): 551-557. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344466401&partnerID=MN8TOARS.
    10.1191/0960327103ht396oa
  272. Marcos, R.; Rocha, E.; Henrique, R.M.F.; Monteiro, R.A.F.. "A new approach to an unbiased estimate of the hepatic stellate cell index in the rat liver: An example in healthy conditions". Journal of Histochemistry and Cytochemistry 51 8 (2003): 1101-1104. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042745504&partnerID=MN8TOARS.
  273. Tokumaru, Y.; Nomoto, S.; Jerónimo, C.; Henrique, R.; Harden, S.; Trink, B.; Sidransky, D.. "Biallelic inactivation of the RIZ1 gene in human gastric cancer". Oncogene 22 44 (2003): 6954-6958. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242406711&partnerID=MN8TOARS.
    10.1038/sj.onc.1206403
  274. Jerónimo, C.; Henrique, R.; Campos, P.F.; Oliveira, J.; Caballero, O.L.; Lopes, C.; Sidransky, D.. "Endothelin B receptor gene hypermethylation in prostate adenocarcinoma". Journal of Clinical Pathology 56 1 (2003): 52-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037245645&partnerID=MN8TOARS.
    10.1136/jcp.56.1.52
  275. Jerónimo, C.; Costa, I.; Conceição Martins, M.; Monteiro, P.; Lisboa, S.; Palmeira, C.; Henrique, R.; Teixeira, M.R.; Lopes, C.. "Detection of gene promoter hypermethylation in fine needle washings from breast lesions". Clinical Cancer Research 9 9 (2003): 3413-3417. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042334827&partnerID=MN8TOARS.
  276. Jerónimo, C.; Varzim, G.; Henrique, R.; Oliveira, J.; Bento, M.J.; Silva, C.; Lopes, C.; Sidransky, D.. "I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma". Cancer Epidemiology Biomarkers and Prevention 11 5 (2002): 445-450. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036095150&partnerID=MN8TOARS.
  277. Jerónimo, C.; Usadel, H.; Henrique, R.; Silva, C.; Oliveira, J.; Lopes, C.; Sidransky, D.. "Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer". Urology 60 6 (2002): 1131-1135. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036899057&partnerID=MN8TOARS.
    10.1016/S0090-4295(02)01949-0
  278. Usadel, H.; Jerónimo, C.; Harden, S.; Engles, J.; Sidransky, D.; Yang, S.; Brabender, J.; Danenberg, K.D.; Danenberg, P.V.. "Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer". Cancer Research 62 2 (2002): 371-375. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037081085&partnerID=MN8TOARS.
  279. Sanchez-Cespedes, M.; Parrella, P.; Nomoto, S.; Cohen, D.; Xiao, Y.; Jeronimo, C.; Koch, W.M.; et al. "Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors". Cancer Research 61 19 (2001): 7015-7019. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035476227&partnerID=MN8TOARS.
  280. Cairns, P.; Esteller, M.; Herman, J.G.; Sidransky, D.; Schoenberg, M.; Jeronimo, C.; Sanchez-Cespedes, M.; et al. "Molecular detection of prostate cancer in urine by GSTP1 hypermethylation". Clinical Cancer Research 7 9 (2001): 2727-2730. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034808413&partnerID=MN8TOARS.
  281. Spafford, M.F.; Koch, W.M.; Reed, A.L.; Califano, J.A.; Xu, L.H.; Eisenberger, C.F.; Yip, L.; et al. "Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis". Clinical Cancer Research 7 3 (2001): 607-612. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034907334&partnerID=MN8TOARS.
  282. Jerónimo, C.; Nomoto, S.; Caballero, O.L.; Usadel, H.; Henrique, R.; Varzim, G.; Oliveira, J.; et al. "Mitochondrial mutations in early stage prostate cancer and bodily fluids". Oncogene 20 37 (2001): 5195-5198. http://www.scopus.com/inward/record.url?eid=2-s2.0-17944367327&partnerID=MN8TOARS.
    10.1038/sj.onc.1204646
  283. Jerónimo, C.; Usadel, H.; Henrique, R.; Oliveira, J.; Lopes, C.; Nelson, W.G.; Sidransky, D.. "Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma". Journal of the National Cancer Institute 93 22 (2001): 1747-1752. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035930097&partnerID=MN8TOARS.
    10.1093/jnci/93.22.1747
  284. Henrique, R.; Azevedo, R.; Bento, M.J.; Domingues, J.C.; Silva, C.; Jerónimo, C.. "Prognostic value of Ki-67 expression in localized cutaneous malignant melanoma". Journal of the American Academy of Dermatology 43 6 (2000): 991-1000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033664108&partnerID=MN8TOARS.
  285. Leong, P.M.; Lisa Kauffman, C.; Margaret Moresi, J.; Wu, L.; Jeronimo, C.; Sidransky, D.M.; Miller, S.J.. "Basal cell carcinoma-like epidermal changes overlying dermatofibromas often reveal loss of heterozygosity in the PTCH gene [2]". Journal of Investigative Dermatology 113 2 (1999): 279-281. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033513393&partnerID=MN8TOARS.
    10.1046/j.1523-1747.1999.00688.x
  286. Henrique, R.M.F.; Sousa, M.E.; Godinho, M.I.; Costa, I.; Barbosa, I.L.; Lopes, C.A.S.. "Immunophenotyping by flow cytometry of fine needle aspirates in the diagnosis of lymphoproliferative disorders: A retrospective study". Journal of Clinical Laboratory Analysis 13 5 (1999): 224-228. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032880195&partnerID=MN8TOARS.
    10.1002/(SICI)1098-2825(1999)13:5<224::AID-JCLA6>3.0.CO;2-5

Intellectual property

Patent
  1. Jerónimo, Carmen. 2012. "Methods and biomarkers for detection of bladder cancer". Norway.
    Pending
Provisional application for patent
  1. 2024. "Prostate cancer recurrence risk calculator".
    Protected

Other

Dataset
  1. Lima, Tânia; António Sousa Barros; Trindade, Fábio; Ferreira, Rita; Adelino F. Leite-Moreira; Barros-Silva, Daniela; Jerónimo, Carmen; et al. Proteome dataset: Characterization of the human urine proteome in Prostate Cancer. Proteomics Identifications Database.
Other output
  1. A DNA Methylation-based Test for Esophageal Cancer Detection. Biomarker Research. 2020. Sofia Salta; Catarina Macedo-Silva; Vera Miranda-Gonçalves; Nair Lopes; Davide Gigliano; Rita Guimarães; Mónica Farinha; et al. https://doi.org/10.21203/rs.3.rs-44848/v3.
    10.21203/rs.3.rs-44848/v3
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/06 PANDORA - A Pan-European Educational Platform, June 15, 2023; Session Liquid Biopsies: searching for cancer biomarkers; Title: Liquid biopsies: Shifting the cancer screening paradigm (Virtual). PANDORA - A Pan-European Educational Platform
PANDORA - cancer academy-COST INNOVATORS GRANT (Torino, Italy)
2023/05 Clinical Epigenetics International Conference (CLEPIC), Szczecin, Poland, May 24-26, 2023; Session- Epigenetic Biomarkers; Title: Simultaneous early detection of the four major cancers by DNA methylation testing in blood-based liquid biopsies using droplet digital PCR. Clinical Epigenetics International Conference
International Society for Molecular and Clinical Epigenetics (Szczecin, Poland)
2023/03 EAU23, Milan, Italy, March 10-13, 2023; Session- Liquid biomarkers; Title: State-of-the-art lecture: Novel biomarkers for diagnosis of prostate cancer. European Association of Urology Meeting 2023
European Association of Urology (Milan, Italy)
2022/07 EAU22, Amsterdam, The Netherlands, July 1-4, 2022; Session- Liquid biomarkers in 2022 and beyond: Ready for primetime?; Title: Liquid and tumour biomarkers in prostate cancer. European Association of Urology Meeting 2022
European Association of Urology (Amsterdam, Netherlands)
2022/07 EAU22, Amsterdam, The Netherlands, July 1-4, 2022; Session- Biomarkers in uro-oncology: From bench to bedside; Title: Non-coding RNAs in liquid biopsy as biomarkers in urological malignancies European Association of Urology Meeting 2022
European Association of Urology (Amsterdam, Netherlands)
2022/06/09 Clinical Epigenetics International Conference (CLEPIC), Szczecin, Poland, June 8-10, 2022; Session- Cancer Epigenetics; Title: Uncovering the role of the epigenetically-regulated miR-30a/c-5p in renal cancer: from biology to the biomarker potential. Clinical Epigenetics International Conference (CLEPIC)
International Society for Molecular and Clinical Epigenetics (iSMOCLEP). (Szczecin, Poland)
2022/05/10 Epi-Besançon 2022- Canceropole Grand-Ouest, Besançon, France, May 10-11,2022; Title: Non-coding RNAs in liquid biopsy as urological cancer biomarkers. Epi-Besançon 2022- Canceropole Grand-Ouest, May 10-11,2022
Canceropole Grand-Ouest (Besançon, France)
2021/10/14 II ASPIC-ASEICA International Meeting on Current Trends in Precision Medicine in Cancer, 14-15 October, (Virtual), 2021 Title: DNA promoter methylation of homologous recombination genes: a predictive biomarker for the responsiveness to PARP inhibitor treatment in testicular germ cell tumors. II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer
Associação Portuguesa de Investigação em Cancro (Porto, Portugal)
2019/10/08 Epitranscriptomics in urological tumors, TransPot (Translational Research Network for Prostate Cancer) Training Course, IPO Porto, Porto, Portugal TransPot (Translational Research Network for Prostate Cancer) Training Course
TransPot (Translational Research Network for Prostate Cancer) Training Couse (Porto, Portugal)
2018/06 First Nordic conference on personalized medicine, Nyborg, Denmark, May 30th - June 1st, 2018; Title: Diagnostic and prognostic epigenetic biomarkers in cancer. First Nordic Conference on Personalized Medicine
Danish Society of Clinical Pharmacology (Nyborg, Denmark)
2018/03 EAU18, Copenhagen, Denmark, March 18-22, 2018; Title: Signalling pathways implicated in therapy: Resistance in urothelium cancer. EAU18
European Association of Urology (Copenhaga, Denmark)
2017/10 The International Bladder Cancer Network 15th Annual Meeting, Lisbon, Portugal, October, 21st-23th, 2017, Title: Comprehensive analysis of Sirtuin family expression in bladder urothelial carcinoma The International Bladder Cancer Network 15th Annual Meeting
IBCN (Lisboa, Portugal)
2017/05 READERS, WRITERS AND ERASERS- The Royal Society- Kavli Royal Society International Centre, Chicheley Hall, Buckinghamshire, UK, May 24 and 25th, 2017; Title: “Epigenetic biomarkers” READERS, WRITERS AND ERASERS
The Royal Society & COST Action CM1406 (Buckinghamshire, United Kingdom)
2017/03 Clinical Epigenetics International Meeting, Düsseldorf, Germany, March 9th –March 10th, 2017; Title: "Epigenetics of Prostate Cancer". Clinical Epigenetics International Meeting
Clinical Epigenetics Society (Düsseldorf, Germany)
2015/02 CANCER EPIGENETICS AND METABOLISM: Connecting the Dots, Cantanhede (Portugal), February 2-3th, 2015; Title: "Epigenetic deregulation in urological tumors: from biology to clinics" CANCER EPIGENETICS AND METABOLISM: Connecting the Dots
Biocant Park-Univ. Coimbra (Cantanhede, Portugal)
2014/10 22nd Meeting of the EAU Section of Urological Research (ESUR), Glasgow (UK), October 9-11 th, 2014; Title: “Development of epigenetic biomarkers for urological cancer detection and prognosis assessment”. 22nd Meeting of the EAU Section of Urological Research (ESUR)
EAU Section of Urological Research (ESUR) (Glasgow, United Kingdom)
2014/10 EMBO Workshop on Epigenetic plasticity: Implications in neural (dys)function, Braga (Portugal), October 22 – 25 th, 2014; Title: "Diagnostic and prognostic epigenetic biomarkers in cancer". EMBO Workshop on Epigenetic plasticity: Implications in neural (dys)function
ICVS-Univ. Minho (Braga, Portugal)
2014/08 IV International Symposium on Translational Oncology of the Barretos Cancer Hospital. Barretos, SP, (Brasil), September 19th to 20th, 2014; Title: “Exploiting epigenetic-based biomarkers: the paradigm of urological cancer”. IV International Symposium on Translational Oncology of the Barretos Cancer Hospital
Barretos Cancer Hospital (Barretos, Brazil)
2014/02/06 41th congress of the International Society of Oncology and Biomarkers & XIV International Symposium on Biology and Clinical Usefulness of Tumor markers. Barcelona (Spain), March 15– 18th, 2014; Title: “Epigenetics and Laboratory Medicine: Development of epigenetic biomarkers for urological cancer detection and prognosis assessment”. Lectures on Biomedicine-University of Córdoba & Maimonides Institute for Biomedical Research (IMIBIC)
IMIBIC (Cordoba, Spain)
2014 Lectures on Biomedicine-University of Córdoba & Maimonides Institute for Biomedical Research (IMIBIC). Cordoba (Spain) February 6th, 2014; Title: “Epigenetics as a tool for cancer detection and prognosis/ prediction assessment”. 41th congress of the International Society of Oncology and Biomarkers & XIV International Symposium on Biology and Clinical Usefulness of Tumor markers
International Society of Oncology and Biomarkers (Barcelona, Spain)
2013/10 COST-MEETING-TD0905-301013-035178. Vilnius (Lithuania), October 30, 31st 2013. Title: “Development of Epigenetic Biomarkers for Urological Cancer Detection” ECOST-MEETING-TD0905-301013-035178
ECOST-TD0905 (Vilnius, Lithuania)
2012/05 GRELL 2012-XXXVII Reunião do Grupo de Registos e de Epidemiologia de cancro dos países de Língua Latina, Porto (Portugal) May 16-18 th 2012; Title: “Immunohistochemistry as an auxiliary tool for oncology”. GRELL 2012-XXXVII Reunião do Grupo de Registos e de Epidemiologia de cancro dos países de Língua Latina
Registos e de Epidemiologia de cancro dos países de Língua Latina (Porto, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023 - Current Evaluation of biomarkers in breast cancer patients undergoing mindfulness-based cognitive therapy
Supervisor
Investigação Clínica e em Serviços de Saúde (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2022 - Current Embracive - a microfluidio avinted technology for non-invase identification and characterization of extracellular veicles in bladder cancer patients
Supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - Current Prostate cancer pre-metastatic niche formation: exosomal osteotropism
Supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - Current Bladder cancer: tackling epigenetic players and immuno-oncology
Supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - Current Epitranscriptomic alterations within renal cancer metabolism reprogramming: uncovering new therapeutic targets
Supervisor
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - Current DNA methylation biomarkers as detection and triage tools in population-based cervical cancer screening program
Supervisor
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023 - 2023 G9a and EZH2: Epimarkers inTesticular Germ Cell Tumors
Supervisor
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022 - 2022 Plasma Extracellular Vesicles As a Source For Biomarkers or Recurrance, Progression  And  Treatment response in bladder Cancer
Co-supervisor
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022 - 2022 Liquid Biopsies: Effects of Long-Time Storage
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022 - 2022 Cell-free DNA methylation as a biomarker for early detecting the four major cancers
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022 - 2022 Promoter methylation of DNA repair genes as biomarker of response to platinum-based chemotherapy: a pancancer investigation
Supervisor
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2018 - 2022 Epigenetic regulation of non-coding RNAs in Prostate Cancer
Supervisor
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/09 - 2021/02 Role of vim in epithelial mesenchymal transition (EMT) in urothelial cancer
Supervisor
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2021 LiKidMiRS: unveiling the diagnostic potential of liquid biopsy-basedcirculating microRNAs in renal cell tumors
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2021 Immunoprofiling of Bladder Cancer: Setting the Basis for Novel Immunotherapeutic Strategies
Supervisor
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2021 - 2021 EFFECT OF MACROPHAGES IN PROSTATE CANCER CELL LINES´ TUMORIGENICITY
Supervisor
Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2015 - 2020/09 Exploring epigenetic profiling as prognostic/predictive markers of endocrine resistance in estrogen receptor positive breast cancer
Supervisor
Medicina e Oncologia Molecular (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2020 - 2020 2D versus 3D Models: Effect of CM-272 on Prostate Cancer Cell Lines
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - 2020 Role of SPARC derived peptides on endothelial/prostate cancer cells monoculture and co-culture models
Co-supervisor
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2020 - 2020 MiR-30 family deregulation in ccRCC
Supervisor
Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020 - 2020 FOXA1 epigenetic regulation in breast cancer
Supervisor
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - 2020 Anti-neoplastic effect of MLo-1302 in Testicular Germ Cell Tumors: comparation with classical differentiating and demethylating agents, ATRA and DAC
Co-supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2019 Study of epigenetic silencing of the tumor suppressor gene SPINT2 in lung cancer
Co-supervisor
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2019 Cell-free DNA methylation as a biomarker for early detection of the three major cancers in males
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2019 Clinical significance of ARID1A and ANXA1 in HER-2 positive breast cancer
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2019 Differential expression of cadherins in bladder cancer: role in epithelial-mesenchymal transition
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2019 Demethylation of the epigenetically silenced androgen receptor gene by a repurposed drug in castration-resistant prostate cancer cell lines
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2018 MIR-371A-3P AS A TOOL FOR SUBTYPING TESTICULAR GERM CELL TUMORS
Supervisor
Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2018 - 2018 Early detection of the three major primary cancers in women by cell-free DNA methylation in liquid biopsies
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2018 MicroRNA-30a hipermethylation as prognostic marker in clear cell renal all carcinoma.
Supervisor
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2018 Monocarboxylate Transporters (MCTs) in Kidney Cancer: The Role of Epigenetic Mechanism
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2018 Interplay between Warburg effect and epigenetic mechanisms in kidney cancer
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2018 Metastatic breast cancer: finding molecular biomarkers in liquid biopsies
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/01 - 2017/06 MicroRNAs deregulation in prostate cancer
Supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2017 A DNA-Methylation Signature by Multiplex Methylight for Prostate Cancer Diagnosis and Prognostication
Supervisor
Medicina Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2017 Decoding the usefulness of miRNAs as biomarkers in breast cancer patients treated with endocrine therapy
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2017 MicroRNA-27a-5p Regulation by Promoter Methylation and MYC Signaling in Prostate Carcinogenesis
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2017 Anti-neoplastic activity of newly synthetized DNMTi in urological tumors
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2017 A DNA-Methylation Signature by Multiplex Methylight for Prostate Cancer Diagnosis and Prognostication
Supervisor
Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2017 Histone post-translational modifications and chromatin remodelers in colorectal cancer
Supervisor
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2017 Circulating MicroRNAs as Markers of Prostate Cancer Progression: a Time-based Approach
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2017 Development of new epigenetic-based biomarkers for renal cell tumors with clinical application
Co-supervisor
Medicina e Oncologia Molecular (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2017 Carcinoma do endométrio: estudo de características patológicas e epigenéticas/Endometrial carcinoma: study of pathological and epigenetic characteristics
Co-supervisor of Carla Maria Magno Bartosch
Medicina e Oncologia Molecular (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2016 Methylome of breast cancer molecular subtypes: diagnosis and prognosis biomarkers
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2016 Role of Chromatin Remodelers in Metastization of Renal Cell Tumors
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2016 Epigenetic Study of Colorectal Cancer: lncRNAs and CIMP Profiling
Supervisor
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2016 - 2016 DNA Methylation for Detection of Primary Colorectal Tumors
Supervisor
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2015 - 2015 MicroRNA promoter methylation: potential biomarkers in prostate cancer Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008/10 - 2014/02 Impact of epigenetic modulators on the malignant phenotype of prostate cancer cells
Supervisor
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008/10 - 2014/02 Histone methylases and demethylases: the role of SMYD3 in prostate carcinogenesis
Co-supervisor of Ana Filipa Quintela Vieira
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2014 The Functional role of histone methylation deregulation in renal tumorigenesis
Co-supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2014 Uncovering PRMT6 deregulation effect in prostate cancer
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2014 Exploiting the interplay between c.-Myc and novel micrornas in prostate carcinogenesis
Supervisor
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2006 - 2014 Expression changes of the ETS family of transcription factors associated with chromosome rearrangements in breast cancer
Co-supervisor of Bárbara Alexandra de Sousa Mesquita
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2013 MicroRNAS Profile: a Promising Ancillary Tool for Accurate Renal Cell Tumor Diagnosis
Co-supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2013 The Role of a Panel of Three Epigenetic Biomarkers in the Detection and Prognosis of Upper Urinary Tract Urothelial Carcinoma
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2013 The Role of a Panel of Three Epigenetic Biomarkers in the Detection and Prognosis of Upper Urinary Tract Urothelial Carcinoma
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2013 The Role of MIR-375 in Prostate Carcinogenesis
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2012 Expression of histone modifying enzymes and histone post-translational marks in colorectal cancer
Co-supervisor
Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2012 - 2012 Epi-drugs regulate H2A.Z via SIRT1 upregulation in prostate cancer
Supervisor
Bioquímica clínica (Master)
Universidade de Aveiro Departamento de Química, Portugal
2012 - 2012 Molecular Markers of Epithelial to Mesenchymal Transition in Prostate Cancer
Co-supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2012 Epigenetic regulation of micrornas in prostate cancer
Co-supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2012 The role of insulin resistance in metabolic reprogramming and lineage commitment
Co-supervisor
Biologia Básica e Aplicada (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2011 Assessment of enoxacin effect on cancer growth and microrna expression in prostate cell lines
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2011 Role of Class I histone deacetylases in bladder carcinogenesis
Supervisor of Susana Maria Pereira Junqueira Pacheco Neto
Oncologia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007 - 2011 Fusion oncogenes involving the ETS family of transcription factors in prostate cancer: target genes and clinical applications
Co-supervisor of Paula Cristina Martins Santos Paulo
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/01 - 2010/12 Development of Epigenetic-based Markers for Molecular Detection of Urological Cancers.
Supervisor of Vera Lúcia Marques Costa
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 - 2010 Analysis of PAX2 gene alterations in renal cell tumors
Supervisor
Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010 - 2010 Identification and characterization of a novel epigenetic biomarker for prostate: the EFEMP 1 story
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009 Prognostic Value Of Methylation Markers In Breast Cancer
Supervisor
Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009 Epigenetic and genetic alterations of DPYD are not predictive of severe toxicity to 5-Fluorouracil-based chemotherapy in gastrointestinal cancer
Supervisor
Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2009 - 2009 Functional and epigenetic characterization of KTN19 in renal neoplasms
Co-supervisor
Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009 Epigenetic and functional characterization of OPCML gene in bladder carcinoma
Supervisor
Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009 Epigenetic Markers as a Tool for Reducing Diagnostic and Treatment Burden in Wilms Tumor
Supervisor
Medicina e Oncologia Molecular (PhD)
Universidade do Porto Faculdade de Medicina, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2024/11/28 - 2024/11/28 IPO Porto Research Center; 2nd Young Researchers day (2024/11/28 - 2024/11/28) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2023/11/09 - 2023/11/09 IPO Porto Research Center; 1st Young Researchers' Day (2023/11/09 - 2023/11/09)
Meeting (President of the Organising Committee)
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2023/02/13 - 2023/02/14 7th Symposium of the Master in Oncology (videoconference), Porto, 13 & 14 of February 2023; Organizer & Scientific Chair (2023/02/13 - 2033/02/14)
Symposium (President of the Organising Committee)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2022/02/14 - 2022/02/15 6th Symposium of the Master in Oncology (videoconference), Porto, 14 & 15 of February 2022; Organizer & Scientific Chair (2022/02/14 - 2022/02/15)
Symposium (President of the Organising Committee)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2021/10/14 - 2021/10/15 II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer, 14-15 October, (Virtual), 2021; Organizer & Scientific Committee (2021/10/14 - 2021/10/15)
Congress (Co-organisor)
Associação Portuguesa de Investigação em Cancro, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2021/05/03 - 2021/05/03 European Cancer Research Summit https://ipoporto.pt/wpsite_2020/wp-content/uploads/2021/03/ECR2021_Programa.pdf (2021/05/03 - 2021/05/03)
Conference (Member of the Organising Committee)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Fundação para a Ciência e a Tecnologia, Portugal
2021/02/22 - 2021/02/23 5 th Symposium of the Master in Oncology (videoconference), Porto, 22 & 23 of February 2021; Organizer & Scientific Chair (2021/02/22 - 2021/02/23)
Symposium
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2020/02/17 - 2020/02/18 4th Symposium of the Master in Oncology, Porto, 17 & 18 of February, 2020; Organizer & Scientific Chair (2020/02/17 - 2020/02/18)
Symposium
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2019/10 - 2019/10 26th Meeting of EAU Section of Urological Research (ESUR19), Porto, 10-12 October, 2019; Organizer & Scientific Chair (2019/10)
Congress (President of the Organising Committee)
European Association of Urology, Netherlands

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2019/04 - 2019/04 3rd Symposium of the Master in Oncology, Porto, 15 & 16 of April, 2019; Organizer & Scientific Chair (2019/04)
Symposium (President of the Organising Committee)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2019/01 - 2019/01 CM1406 EpiChemBio Joint WorkGroup Meeting (WG2&3) Epigenetic reprogramming and epigenetic technologies, Paris, France 21-22 January 2019; Co-organizer (2019/01)
Conference (Co-organisor)
2018/05 - 2018/05 2nd Symposium of the Master in Oncology, 7-8 May 2018; Organizer & Scientific Chair (2018/05)
Symposium (President of the Organising Committee)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/09 - 2017/09 Joint EpiChemBio and MuTaLig COST Actions Meeting, Porto, Portugal, September 22-24, 2017); Co-chair (2017/09)
Congress (Co-organisor)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2017/04 - 2017/04 1st Symposium of the Master in Oncology, 10-11 April 2017; Organizer & Scientific Chair (2017/04 - 2017/04)
Symposium (President of the Organising Committee)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/04 - 2016/04 Second ASPIC International Congress; Porto, Portugal, April 28, 29, 2016); Co-chair of the scientific committee (2016/04 - 2016/04)
Congress (Co-organisor)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2016/04 - 2016/04 Advanced Course in Immuno-oncology, Porto, Portugal, April 27, 2016; Co-organizer (2016/04 - 2016/04)
Congress (Member of the Scientific Committee)
Associação Portuguesa de Investigação em Cancro, Portugal
2014/11 - 2014/11 First ASPIC International Congress, Lisbon, Portugal, November 25,26, 2014; Scientific Co-chair (2014/11 - 2014/11)
Congress (Member of the Scientific Committee)
Associação Portuguesa de Investigação em Cancro, Portugal
2012/10 - 2012/10 A One Day Symposium with Carlos Caldas sponsored by EACR, Porto, Portugal, October 29, 2012; Member of the organizing scientific committee (2012/10 - 2012/10)
2011/01/28 - 2011/01/29 Second Meeting of the European Consortium-EpiDiaCan, Porto, 28th -29th January, 2011; Organizer & Scientific Chair (2011/01)
Conference (President of the Organising Committee)
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/11 OPPONENT IN AGGREGATION EVALUATION COMMITTEE; Health Sciences; School of Medicine, University of Minho; Candidate: Fernanda Cristina Gomes Sousa Marques
(Thesis) Main arguer
Fernanda Cristina Gomes Sousa Marques (Aggregation)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2023 PhD in Biology, School of Sciences, University of Minho, Braga, Portugal; Title: Towards valorization of beehive natural products: unravelling Portuguese propolis bioactivities and potential; Student: Ana Sofia Pereira de Freitas
(Thesis) Main arguer
Ana Sofia Pereira de Freitas (PhD)
Universidade do Minho Escola de Ciências, Portugal
2022 PhD in Molecular Biosciences, Autonomous University of Madrid, Spain; Title: Understanding bladder cancer through mouse models and epigenetic targets; Student: Ester Munera Maravilla
(Thesis) Main arguer
Ester Munera Maravilla (PhD)
Universidad Autonoma de Madrid Facultad de Ciencias, Spain
2022 PhD in Translational Medicine; School in Life Sciences, Università degli studi della Campania Luigi Vanvitelli, Naples, Italy (External Evaluator for European Degree); Title: Exosome Functionalization in Acute Myeloid Leukemia; Student: Crescenzo Massaro
Thesis Member
Crescenzo Massaro (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Medicina di Precisione, Italy
2022 PhD in Health Sciences, School of Medicine, University of Minho, Braga, Portugal; Title: Characterization of the anticancer efficacy and safety profiles of novel synthetic compounds; Student: Olívia Alexandra Pontes
(Thesis) Main arguer
Olívia Alexandra Pontes (PhD)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2021 PhD in Translational Medicine; European Degree, School in Life Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy; Title: Undifferentiated Connective Tissue Disease at Risk for Systemic Sclerosis: development of a Predictive Score and a risk stratification tool; Student: Antonella Riccardi
(Thesis) Main arguer
Antonella Riccardi (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Medicina di Precisione, Italy
2021 PhD in Translational Medicine; European Degree, School in Life Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy; Title: Mechanism of Resistance to EGFR-targeted therapies; Student: Nunzia Matrone
(Thesis) Main arguer
Nunzia Matrone (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Medicina di Precisione, Italy
2021 PhD in Translational Medicine; European Degree, School in Life Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy; Title: RAS mutant allele fraction in plasma predicts response to anti-angiogenic based first-line treatment in metastatic colorectal cancer; Student: Giulia Martini
(Thesis) Main arguer
Giulia Martini (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Scienze Mediche Traslazionali, Italy
2021 PhD in Translational Medicine; European Degree, School in Life Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy; Title: Mulple Roles of AXL Receptor Tyrosine Kinase in Colorectal Cancer Developmen; Student: Bernadette Lauensteine
(Thesis) Main arguer
Bernadette Lauensteine (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Scienze Mediche Traslazionali, Italy
2019 PhD in Translational Medicine; European Degree, School in Life Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy; Title: Unraveling the oncogenic role of CBX2 in human Leukemia: mechanisms regulating its protein stability and functional activity; Student: Lidio Conti
(Thesis) Main arguer
Lidio Conti (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Scienze Mediche Traslazionali, Italy
2019 PhD in Biochemistry and Biotechnology; Faculty of Pharmaceutical, Biomedical and Veterinary Sciences (FBD) - University of Antwerp, Belgium; Title: Epigenetic profiling of adverse lifestyle conditions and nutraceutical interventions in health and disease; Student: Ken Declerck
(Thesis) Main arguer
Ken Declerck (PhD)
Universiteit Antwerpen Departement Biochemie and Biotechnologie, Belgium
2019 PhD in Chemistry-Catalysis and Sustainability Specialization, University of Coimbra, Coimbra, Portugal; Title: Development of Metal Catalysts for Activation of CO andCO2.Synthesis of Small Ring Heterocycles with Potential Biological Activity; Student: Ana Sofia Pereira de Freitas
(Thesis) Main arguer
Lucas Danilo Dias (PhD)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2019 PhD in Cellular Signaling, Faculty of Medicine and Health Sciences, University of Alcalá, Madrid, Spain; Title: Preclinical study of potential therapeutic strategies based on epigenetics for bladder cancer; Student: Cristina Segovia de Andrés
(Thesis) Main arguer
Cristina Segovia de Andrés (PhD)
Universidad de Alcalá Facultad de Medicina y Ciencias de la Salud, Spain
2017 PhD in Translational Medicine; School in Life Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy (External Evaluator for European Degree); Title: The Emerging Role of tumor-derived exosomes in Acute Myeloid Leukemia; Student: Cristina Giorgio
(Thesis) Arguer
Cristina Giorgio (PhD)
Università degli Studi della Campania Luigi Vanvitelli Dipartimento di Scienze Mediche Traslazionali, Italy
2017 PhD in Biomedical Sciences; University of Vilnius, Lithuania (External Evaluator for European Degree); Title: The Emerging Role of tumor-derived exosomes in Acute Myeloid Leukemia; Student: Kristina Daniunaite
(Thesis) Arguer
Kristina Daniunaite (PhD)
Vilniaus kolegija, Lithuania
2017 PhD in Health Sciences, School of Health Sciences, University of Minho, Braga, Portugal; Title: Monocarboxylate Transporters (MCTs) in breast cancer aggressiveness: therapeutic targeting and regulatory mechanisms; Student: Luisa Filipa Morais dos Santos.
(Thesis) Main arguer
Luisa Filipa Morais dos Santos (PhD)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2016 PhD in Genetics; Department of Genetics; University of Córdoba, Spain; Title: DNA demethylation through 5-methylcytosine excision. Molecular basis and potential applications; Student: Jara Teresa Parrilla Doblas
(Thesis) Main arguer
Jara Teresa Parrilla Doblas (PhD)
Universidad de Córdoba Facultad de Ciencias, Spain
2016 PhD in Health Sciences branch of Biomedical Sciences; Faculty of Medicine, University of Coimbra, Portugal; Title: Oxidative stress versus epigenetic– Role in susceptibility, development, and progression of myeloid neoplasms; Student: Ana Cristina Pereira Gonçalves
(Thesis) Main arguer
Ana Cristina Pereira Gonçalves (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 PhD in Pharmaceutical Sciences; School of Pharmaceutical Sciences; University of Geneve, Switzerland; Title: EZH2 induces methylation of ERG enhancing its transcriptional and transforming activity; Student: Laura Curti
(Thesis) Main arguer
Laura Curti (PhD)
Université de Genève Faculté des Sciences, Switzerland

Université de Genève, Switzerland
2016 PhD in Veterinary Sciences; Faculty of Veterinary, University of Lisbon, Portugal; Title: The role of JAGGED1 in adult angiogenesis and in solid tumor development; Student: Ana Rita Ponce Álvares de Águeda Pedrosa
(Thesis) Main arguer
Ana Rita Ponce Álvares de Águeda Pedrosa (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2015 PhD in Biomedicine, Faculty of Health Sciences, Univ. of Beira Interior (UBI), Covilhã, Portugal; Title: Androgens and Calcium-binding protein Regucalcin in the control of Prostate cells metabolism and survival: implications in Carcinogenesis; Student: Cátia Alexandra Vicente Vaz
(Thesis) Main arguer
Cátia Alexandra Vicente Vaz (PhD)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015 PhD in Biomedical Sciences specialty Biopathological Sciences, Faculty of Medicine, University of Lisbon, Portugal; Title: Effects of chemotherapy and radiotherapy in rectal cancer: significance of different cellular outcomes in tumor behavior; Student: Joana Maria Tato Ribeiro da Costa
(Thesis) Main arguer
Joana Maria Tato Ribeiro da Costa (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 PhD in Health Sciences and Technology, speciality in Cellular and Molecular Biology of the Faculty of Pharmacy, University of Coimbra, Portugal; Title: Long non-coding RNAs at the service of p53; Student: Carlos Manuel Almeida Guedes de Melo
(Thesis) Main arguer
Carlos Manuel Almeida Guedes de Melo (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014 PhD in Health Sciences, School of Health Sciences, University of Minho, Braga, Portugal; Title: Transcription Factors and Epigenetics in breast: new findings in CDH3/P cadherin Gene regulation; Student: André João Almeida Marques Soares de Albergaria.
(Thesis) Main arguer
André João Almeida Marques Soares de Albergaria (PhD)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2014 President of the juries of the MSc In Oncology 2014-2023: 78 Masters
President of the jury
MSc Students (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Association member

Society Organization name Role
2015/01 - Current European Association of Urology
2013/01/01 - Current Portuguese Association for Cancer Research- EACR Afilliated Member
2002 - Current European Association for Cancer Research
1999 - Current American Association for Cancer Research
1992/01 - Current Order of Biologists/Ordem dos Biólogos Member

Committee member

Activity description
Role
Institution / Organization
2024/05/01 - Current President of the Portuguese Association for Cancer Research (ASPIC) Committee member since 2024
President / Vice-president
Associação Portuguesa de Investigação em Cancro, Portugal
2023/11 - Current Chair of the European Association of Urology (EAU) Section of Urological Research ( ESUR)
Other
European Association of Urology, Netherlands
2022 - Current Management Committee member of the COST ACTION, entitled IMMUNO-model -Modelling Immunotherapy response and toxicity in Cancer- CA21135
Member
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2021/10 - Current Certified auditor of the Organisation of European Cancer Institutes
Other
Organisation of European Cancer Institutes, Belgium
2021/05 - Current President of the North Delegation -Order of Biologists
2022/07/02 - 2024/03/30 Vice-President of the Portuguese Association for Cancer Research (ASPIC)
President / Vice-president
Associação Portuguesa de Investigação em Cancro, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2017 - 2021 Management Committee member of COST Action European Epitranscriptomics Network-CA16120-EPITRAN
Other
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2015 - 2019 Management Committee member of Action Epigenetic Chemical Biology (EPICHEMBIO) CMST COST Action CM1406 and Chair of Working group WG2- Epigenetic Technology
Other
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/01/01 - 2016 Executive committee member; Treasurer of ASPIC -Portuguese Association for Cancer Research
Other
Associação Portuguesa de Investigação em Cancro, Portugal
2013 - 2016 Management Committee member of Action TD0905- Chemistry and Molecular Sciences and Technologies (CMST) - Epigenetics: Bench to Bedside, member WG4
Other
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Consulting

Activity description Institution / Organization
2023/02/27 - Current Pro bono, Scientific Consultant of Karion Therapeutics company, Braga, Portugal Karion Therapeutics, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2014 - Current Evaluation committee of FCT Investigator call- 2013 e 2015
Evaluator
Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2014 - Current Evaluation committee of EU_COST OC-2014-1(European Cooperation in Science and Technology
Evaluator
European Cooperation in Science and Technology, Belgium
2003 - Current Evaluation of scientific Grants: 2003-Health Research Board,IR 2006-Associazione Italiana per la Ricerca sul Cancro 2006,2007-National Medical Research CouncilSingapore 2007, 2012,2015, 2019-Cancer ResearchWILLIAMS BARKER, MRC,UK; 2011,2016, 2018,2022, 2023 -Swiss National Science Foundation; 2013,2015-Swiss League Against Cancer; 2013,2015-Austrian Science Fund; 2014, 2020-PROSTATE CANCER UK 2016,2017,2023-Fund for Scientific ResearchBL; 2019-Fundaciò MaratóSP, 2022-Institut National Du Cancer, FR; 2023-Novo Nordik Foden Laureate Research G,NO
Evaluator
Health Research Board (HRB)-Ireland, Ireland

Associazione Italiana per la Ricerca sul Cancro, Italy

National Medical Research Council, Singapore

Cancer Research UK, United Kingdom

Binational Science Foundation, Israel

Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, Switzerland

Swiss League Against Cancer, Switzerland

Fonds zur Förderung der wissenschaftlichen Forschung, Austria

European Cooperation in Science and Technology, Belgium

Agence nationale de la recherche, France

Fundació la Marató de TV3, Spain

Institut National du Cancer, France

Novo Nordik Foden , Norway

Journal scientific committee

Journal title (ISSN) Publisher
2022 - Current Frontiers in Genetics
2022 - Current Frontiers in Cell and Developmental Biology
2014 - Current Clinical Epigenetics (1868-7083) Springer-Verlag
2019 - 2024 Guest Editor of the Topical Collection "Germ Cell Tumors"-CANCERS MDPI
Distinctions

Award

2004 Scholar in training award (co-authorship)-AACR
American Association for Cancer Research, United States

Other distinction

2007 1ª Menção Honrosa do Prémio LabMED 2006
2007 2ª Menção Honrosa do Prémio LabMED 2006
2005 1ª Menção Honrosa do Prémio LabMED 2004