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Mariana Ladeiro Afonso. PhD student of the Doctoral Programme in Health Sciences at the Institute of Microbiology at the Faculty of Medicine of University of Coimbra, working on the project “Candida spp. escape to Neutrophil Extracellular Traps: Role of 3’-nucleotidase/nuclease”. Has published 1 articles in peer-reviewed journals. Participated in 4 event(s). Participates and/or participated as a PhD Fellow in 1 project(s) and Research Fellow in 1 project(s).
Identification

Personal identification

Full name
Mariana Ladeiro Afonso

Citation names

  • Afonso, Mariana

Author identifiers

Ciência ID
D01A-B93A-2D56
ORCID iD
0000-0001-6437-697X

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Upper intermediate (B2) Proficiency (C2) Advanced (C1)
Education
Degree Classification
2025
Ongoing
 Doctoral Programme in Health Sciences (Doutoramento)
Major in Ciências Biomédicas
Faculdade de Medicina da Universidade de Coimbra, Portugal
"Candida spp. escape. to Neutrophil Extracellular Traps: Role of 3'-nucelotidase/nuclease" (THESIS/DISSERTATION)
2021/01 - 2021/06
Concluded
 Training Course – Research Methodologies in Life Sciences, Nature Sciences and Engineering (Diploma de especialização)
Universidade de Coimbra, Portugal
2018/10/05 - 2020/11/13
Concluded
 Master's degree in Biochemistry. During this period: collaboration in monitoring students in training (undergraduate and master's) from FMUC and FCTUC (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
"Involvement of the purinergic system in the host-microbe interaction" (THESIS/DISSERTATION)
 17
2014/10/25 - 2017/11/28
Concluded
 Bachelor's degree in Biotechnology with participation in Erasmus + at the Uniwersytet Przyrodniczy w Poznaniu in Poland from 28/09/2016 to 30/01/2017. (Licenciatura)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
"Quality control mechanisms are up-regulated in epicardial adipose tissue from heart failure patients." (THESIS/DISSERTATION)
 14
Affiliation

Others

Category
Host institution 		Employer
2020/04/01 - 2020/12/31 Voluntary collaboration in the diagnosis of COVID-19 / SARS-CoV-2 Universidade de Coimbra Faculdade de Medicina, Portugal
2017/05 - 2017/10 Professional Internship - "Quality control mechanisms are up-regulated in epicardial adipose tissue from heart failure patients.". Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Projects

Grant

Designation Funders
2021/12 - Current Candida spp. escape to Neutrophil Extracellular Traps: Role of 3’-nucleotidase/nuclease
2021.07033.BD
PhD Student Fellow
Fundação para a Ciência e a Tecnologia, Portugal
Ongoing
2021/03 - 2021/10 I&D PureAir@Automotive - equipamentos de purificação do ar para veículos rodoviários de passageiros
POCI-01-02B7-FEDER-070195
Research Fellow
Ongoing

Contract

Designation Funders
2023/02/01 - 2026/01/31 O papel do varioma de Candida albicans na sua interação com o hospedeiro humano
2022.01376.PTDC
10.54499/2022.01376.PTDC
Universidade de Aveiro, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. Afonso, Mariana. ""Candida albicans 5’-3’-ectonucleotidase activity: a comparative study of isolates from different human infection niches." Mariana Afonso, Bernardo Bandeira, Rodrigo A. Cunha, José Roberto Meyer-Fernandes, Teresa Gonçalves, Lisa Rodrigues". Paper presented in Microbiotec23- Congress of Microbiology and Biotechnology 2023, 2023.
  2. Rodrigues, Lisa ; Afonso, Mariana; Almeida, Ana Catarina; Cunha, Rodrigo A.; Gonçalves, Teresa. "Host CD73 modulates Candida albicans driven neutrophils extracellular traps formation". Paper presented in XII Meeting of the Brazilian Purine Club - Curitiba, Brazil, 2023, 2023.
  3. Afonso, Mariana. ""Host ecto-5’-nucleotidase (CD73) suppression impairs neutrophils NET formation response upon Candida albicans infection." Mariana Afonso, Lisa Rodrigues, Ana Catarina Almeida, Rodrigo A. Cunha, Teresa Gonçalves". Paper presented in 11th Trends in Medical Mycology, Athens, Greece, 2023.
  4. Afonso, Mariana; Rodrigues, Lisa ; Almeida, Ana Catarina; Cunha, Rodrigo A.; Gonçalves, Teresa. "Host ecto-5'-nucleotidase (CD73) suppression impairs neutrophils NET formation response upon Candida albicans infection". Paper presented in 11th Congress on Trends in Medical Mycology (TIMM-11) - Athens, Greece, 2023, 2023.
  5. DOMINGUES, RITA; Afonso, Mariana; Calheiros, Daniela; Nogueira, Célia; Michael Brad Strader; Jay E. Slater; Todo-Bom, Ana; et al. "Characterization of Alternaria alternata extracellular vesicles. Proteome and interaction with host cells.". Paper presented in 2nd Meeting of the Portuguese Network Vesicles, 2023.
  6. Afonso, Mariana. ""Candida - Neutrophil interaction: The Role of Extracellular Nucleotide Metabolism." Mariana Afonso, Ana Rita Mestre, Guilherme Silva, Ana Catarina Almeida, Rodrigo A. Cunha, José Roberto Meyer-Fernandes, Teresa Gonçalves, Lisa Rodrigues". Paper presented in FEBS Advanced Lecture Course HFP2022: “Molecular Mechanisms of Host-Pathogen Interactions and Virulence in Human Fungal Pathogens”, 2022.
  7. Afonso, Mariana. ""Extracellular nucleotide metabolism in the context of Candida-neutrophils interaction"; Mariana Afonso, Ana Rita Mestre, Guilherme Silva, Rodrigo A. Cunha, José Roberto Meyer-Fernandes, Teresa Gonçalves, Lisa Rodrigues". Paper presented in Candida and Candidiasis 2021 online congress, 2021.
  8. Afonso, Mariana; Mestre, Ana Rita; Silva, Guilherme; Cunha, Rodrigo A.; Meyer-Fernandes JR; Gonçalves, Teresa; Rodrigues, Lisa. "Extracellular nucleotide metabolism in the context of Candida-neutrophils interaction". Paper presented in Candida and Candidiasis 2021, 2021.
Journal article
  1. Correia, Gil; Rodrigues, Luís; Afonso, Mariana; Mota, Marta; Oliveira, Joana; Soares, Rui; Tomás, Ana Luísa; et al. "SARS-CoV-2 air and surface contamination in residential settings". Scientific Reports 12 1 (2022): http://dx.doi.org/10.1038/s41598-022-22679-y.
    10.1038/s41598-022-22679-y
  2. Afonso, Mariana. "Candida extracellular nucleotide metabolism promotes Neutrophils Extracellular Traps escape; Mariana Afonso, Ana Rita Mestre, Guilherme Silva, Ana Catarina Almeida, Rodrigo A. Cunha, José Roberto Meyer-Fernandes, Teresa Gonçalves, Lisa Rodrigues". Frontiers in Cellular and Infection Microbiology (2021): DOI: 10.3389/fcimb.2021.678568.
    Published
Activities

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/09/17 - 2021/09/17 Science Communication Activities: Participation in the MicroScience Photo Gallery- Microorganismos de estimação: associated to the International Microorganism Day 2021, Exploratório - Ciência Viva, Coimbra, Portugal
2020/10/17 - 2020/11/05 Science Communication Activities: Participation in the MicroScience Photo Gallery- Microorganismos de estimação: associated to the International Microorganism Day 2020, Exploratório - Ciência Viva, Coimbra, Portugal
Exhibition
 International Day of the Microorganism 2020
2016/03/16 - 2016/03/17 Participation in Biotechnology Days - Católica Faculty of Biotechnology
Congress
 Biotechnology Days

Association member

Society Organization name Role
2022 - Current Portuguese Biochemical Society
2021/02 - Current Microbiology Society