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Identification

Personal identification

Full name
Mónica Alexandra Teotónio Fernandes

Citation names

  • Fernandes, Mónica T
  • Mónica Teotónio Fernandes

Author identifiers

Ciência ID
D21D-88F0-DBD1
ORCID iD
0000-0002-1206-1367

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Medical and Health Sciences - Health Sciences - Infectious Diseases

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Portuguese (Mother tongue)
French Intermediate (B1) Intermediate (B1) Elementary (A2) Upper intermediate (B2) Intermediate (B1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Outputs

Publications

Book chapter
  1. Fernandes, Mónica T; Lousada H; Castelo-Branco P. "Histone modifications in diseases". In Histone Modifications in Therapy. Academic Press, 2020.
    Published
Conference abstract
  1. Mónica Teotónio Fernandes; Apolónio, Joana; Esteves, Filipa; De Sousa-Coelho, Ana Luísa; MARREIROS, ANA; Castelo-Branco Pedro. "Unveiling a Novel Epigenetic Biomarker for Personalized Medicine in Gliomas". Paper presented in Revista Portuguesa de Farmacoterapia, Faro, 2023.
    Published
  2. Fernandes, Mónica T. "Identification of DNA Methylation-based Prognostic Biomarkers in Acute Myeloid Leukemia Patients with a Normal Kariotype". Paper presented in Congresso Nacional dos Farmacêuticos, online, 2020.
    Published
  3. Cardoso, Candida; Pestana, Daniel; Ramalhete, Sara; Mestre, André; MARREIROS, ANA; Fernandes, Mónica T; Pedro Castelo-Branco. "Prognostic Markers in Intermediate Patients with Acute Myeloid Leukemia". Paper presented in Acute Myeloid Leukemia”. Poster apresentado em 3as, Albufeira, 2019.
    Published
  4. Pestana, Daniel; Cardoso, Candida; Mestre, André; Ramalhete, Sara; MARREIROS, ANA; Mónica Teotónio Fernandes; Pedro Castelo-Branco. "Epi-Hotspots in cancer initiation". Paper presented in 3as Jornadas do Algarve Biomedical Center, Albufeira, 2019.
    Published
Conference paper
  1. De Sousa-Coelho, Ana Luísa; Fernandes, Mónica T. "O impacto do líder de grupo nas aulas laboratoriais / The impact of the group leader in laboratory classes". Paper presented in 8º Congresso Nacional de Práticas Pedagógicas no Ensino Superior, 2022.
    Published
  2. Fernandes, Mónica T; De Sousa-Coelho, Ana Luísa. "A metodologia da sala de aula invertida aplicada ao ensino prático laboratorial em contexto de pandemia/ The flipped classroom methodology applied to practical laboratory teaching in the context of a pandemic". Paper presented in 7.º Congresso Nacional de Práticas Pedagógicas no Ensino Superior (CNaPPES.21), 2021.
    Published
Conference poster
  1. Fernandes, Mónica T; Apolónio, Joana; De Sousa-Coelho, Ana Luísa; Ana Marreiros; Castelo-Branco, Pedro. Corresponding author: Fernandes, Mónica T. "CITED4 methylation is a novel prognosis biomarker in gliomas.". Paper presented in EACR-AstraZeneca Cancer Epigenetics, 2023.
  2. Alexandra Matos; Sofia Melo Calado; De Sousa-Coelho, Ana Luísa; Bragança, José; Fernandes, Mónica T. Corresponding author: Fernandes, Mónica T. "Functional assays reveal a role for CITED2 in the stemness properties of glioblastoma.". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  3. Apolónio, Joana Dias; Gabriela Valadas; Fernandes, Mónica T; Morera, José L.; Castelo-Branco, Pedro. "THOR, a targetable epigenetic biomarker in BC, finding new paths for its use.". Paper presented in XX Jornadas de Senologia, 2023.
  4. De Sousa-Coelho, Ana Luísa; Fernandes, Mónica T. Corresponding author: Fernandes, Mónica T. "CITED2 gene expression levels in normal and cancer stem cells.". Paper presented in EACR Conference Stem Cell Biology, Cancer Plasticity and Therapeutic Potential, 2023.
  5. Fernandes, Mónica T; Apolónio, Joana ; Pedro Castelo-Branco; Bragança, José. "CITED4 methylation status is a potential prognostic biomarker for glioma in elderly patients.". Paper presented in International Conference Ageing without borders,, 2022.
  6. Fernandes, Mónica T; Apolónio, Joana ; Pedro Castelo-Branco; Bragança, José. "CITED4 role in gliomas - revisiting previous studies and providing new clues". Paper presented in V Encontro Anual do Algarve Biomedical Center, 2022.
  7. Fernandes, Mónica T; Apolónio, Joana ; Pedro Castelo-Branco; Bragança, José. "CITED4 hypomethylation in the 3'UTR is associated with an adverse prognosis in glioblastoma.". Paper presented in 5th ASPIC International Congress, 2022.
  8. Fernandes, Mónica T; Victor Yassuda; De Sousa-Coelho, Ana Luísa. "Avaliação dos níveis de expressão génica de TRIB1, TRIB2 e TRIB3 em amostras de pacientes com cancro do cólon e do reto / Assessment of gene expression levels of TRIB1, TRIB2 and TRIB3 in samples from patients with colon and rectal cancer.". Paper presented in I Jornadas das Tecnologias da Saúde do CHUA, 2022.
  9. Fernandes, Mónica T; Mendes-Silva, Leonardo; Sofia M. Calado; Bragança, José. "Exploring CITED2 role in the stemness properties of glioblastoma cancer stem cells.". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2022.
  10. Fernandes, Mónica T; Mendes-Silva, Leonardo; Sofia M. Calado; Bragança, José. "Evaluation of the expression of potential CITED2-interacting partners in glioblastoma cancer stem cells". Paper presented in Meeting ASPIC-ASEICA (Portuguese and Spanish Associations for Cancer Research), 2021.
  11. Fernandes, Mónica T. "Estudo de alterações genéticas e epigenéticas no gene CITED4 e seu impacto em gliomas / Study of CITED4 genetic and epigenetic alterations and its impact on gliomas". Paper presented in III ENJIO (Encontro Nacional de Jovens Investigadores em Oncologia / National Meeting of Oncology Young Investigators), 2021.
  12. Fernandes, Mónica T. "Identification of DNA Methylation-based Prognostic Biomarkers in Acute Myeloid Leukemia Patients with Normal Cytogenetics.". Paper presented in Congresso Nacional dos Farmacêuticos, 2020.
  13. Cardoso C; Pestana D; Mestre A; Marreiros A; Fernandes, Mónica T; Castelo-Branco P. "Prognostic Markers in Intermediate Patients with Acute Myeloid Leukaemia". Paper presented in 3as Jornadas do Algarve Biomedical Center, 2019.
  14. Pestana D; Cardoso C; Ramalhete SV; Mestre A; Fernandes, Mónica T; Marreiros A; Castelo-Branco P. "Epi-hotspots in cancer initiation". Paper presented in 3as Jornadas do Algarve Biomedical Center, 2019.
  15. Ramalhete SV; Castelo-Branco P; Fernandes, Mónica T. "CPNE8 differential methylation as a prognostic biomarker in Acute Myeloid Leukaemia". Paper presented in II Poster Sunset Session ESS-UAlg, 2018.
  16. Fernandes, Mónica T; Ramalhete SV; Castelo-Branco P. "APOC2 epimutation predicts a favorable prognosis in Acute Myeloid Leukaemia". Paper presented in 3.o Congresso Internacional da Associação Portuguesa de Investigação em Cancro (ASPIC), 2018.
  17. Fernandes, Mónica T; ribeiro ar; Castelo-Branco P. "Uncovering epigenetic DNA methylation in drivers of leukemogenesis". Paper presented in 2as Jornadas do ABC (Algarve Biomedical Center), 2018.
    10.1158/1055-9965.disp-10-b62
  18. Fernandes, Mónica T; Dos Santos NR; Ghezzo MN; Pacheco-Leyva, Ivette; Rodrigues PM; Alves NL. "FoxN1-dependent thymic epithelial cells foster the development of T-cell acute lymphoblastic leukemia.". Paper presented in T-ALL Workshop 2017, 2017.
  19. Ghezzo MN; Fernandes, Mónica T; Rodrigues MR; Alves NL; Dos Santos NR. "FoxN1-dependent thymic epithelial cells foster the development of T-cell acute lymphoblastic leukemia in a mouse model". Paper presented in 1st International Venice Thymus Meeting, 2015.
  20. Fernandes, Mónica T; Ghezzo MN; Dos Santos NR. "Lymphotoxin-ß receptor activation in thymic microenvironmental cells promotes T-cell acute lymphoblastic leukaemia". Paper presented in 1st International Venice Thymus Meeting, 2015.
  21. Ghezzo MN; Fernandes, Mónica T; Dos Santos NR. "Thymic microenvironment in the malignant transformation of thymocytes in TEL-JAK2-induced leukaemia". Paper presented in 1.o Congresso Internacional da Associação Portuguesa de Investigação em Cancro (ASPIC), 2014.
  22. Fernandes, Mónica T; Ghezzo MN; povoa v; ribeiro ar; Dejardin, Emmanuel; Alves NL; Ghysdael J; Barata JT; Dos Santos NR. "LTßR in microenvironmental cells modulates surface lymphotoxin expression on leukaemic T cells and promotes leukaemogenesis". Paper presented in 1.o Congresso Internacional da Associação Portuguesa de Investigação em Cancro (ASPIC), 2014.
  23. Fernandes, Mónica T; povoa v; ribeiro ar; Alves NL; Barata JT; Dos Santos NR. "Lymphotoxin-beta Receptor Signalling in Microenvironmental Cells Supports T-Cell Leukemogenesis". Paper presented in Reunião Anual da Sociedade Belga de Imunologia, 2013.
  24. Fernandes, Mónica T; Ghezzo MN; Dos Santos NR. "Lymphotoxin-beta Receptor Signalling in Microenvironmental Cells Supports T-Cell Leukemogenesis". Paper presented in 14th International TNF Conference, 2013.
  25. Fernandes, Mónica T; Ghezzo MN; Dos Santos NR. "Lymphotoxin cooperates with the TEL-JAK2 fusion oncogene in thymocytes malignant transformation". Paper presented in EHA-ESH Second Scientific Workshop on T-Cell Acute Lymphoblastic Leukemia, 2013.
  26. Ghezzo MN; Fernandes, Mónica T; Dos Santos NR. "FoxN1 expression in the thymic stroma promotes T-cell leukemia in TEL-JAK2 transgenic mice.". Paper presented in Second ESH-EHA Scientific Workshop on T-Cell Acute Lymphoblastic Leukemia, 2013.
  27. Fernandes, Mónica T; Ghezzo MN; Dos Santos NR. "Lymphotoxin cooperates with the TEL-JAK2 fusion oncogene in thymocyte malignant transformation". Paper presented in THYMUS International Conference 2012, 2012.
  28. Fernandes, Mónica T; Ghezzo MN; Dos Santos NR. "FOXN1 expression in the thymic stroma promotes T-cell leukemia in TEL-JAK2 transgenic mice". Paper presented in 5.ª edição do Encontro Nacional sobre Sinalização Celular, 2011.
  29. Fernandes, Mónica T; Al-Dalali FA; Silva RC; Ghezzo MN; Dos Santos NR. "Identification of genetic alterations occurring in pre-T cell receptor-deficient T-cell leukemia". Paper presented in 5.ª edição do Encontro Nacional sobre Sinalização Celular, 2011.
  30. Fernandes, Mónica T; Silva RC; Ghezzo MN; Dos Santos NR. "The role of lymphotoxin-beta receptor signalling in T-cell acute lymphoblastic leukemia development". Paper presented in 5.ª edição do Encontro Nacional sobre Sinalização Celular, 2011.
  31. Fernandes, Mónica T; da Silva RC; Ghezzo MN; Dos Santos NR. "The role of lymphotoxin-beta receptor signaling in T-cell acute lymphoblastic leukemia development". Paper presented in 4.ª edição do Encontro Nacional sobre Sinalização Celular, 2010.
Journal article
  1. Cândida Cardoso; Daniel Pestana; Sreemol Gokuladhas; Ana D. Marreiros; Justin M. O'Sullivan; Alexandra Binnie; Mónica TFernandes; Pedro Castelo-Branco. "Identification of Novel DNA Methylation Prognostic Biomarkers for AML With Normal Cytogenetics". JCO Clinical Cancer Informatics (2024): https://doi.org/10.1200/CCI.23.00265.
    10.1200/CCI.23.00265
  2. José Bragança; Rute Luísa Cabrita Pinto; Barbara Sofia Marques da Silva; Nuno Marques; Helena S. Leitão; Mónica T. Fernandes. "Charting the Path: Navigating Embryonic Development to Potentially Safeguard against Congenital Heart Defects". Journal of Personalized Medicine (2023): http://dx.doi.org/10.3390/jpm13081263.
    Published • 10.3390/jpm13081263
  3. Cátia D. Correia; Anita Ferreira; Mónica T. Fernandes; Bárbara M. Silva; Filipa Esteves; Helena S. Leitão; José Bragança; Sofia M. Calado. "Human Stem Cells for Cardiac Disease Modeling and Preclinical and Clinical Applications—Are We on the Road to Success?". Cells (2023): http://dx.doi.org/10.3390/cells12131727.
    10.3390/cells12131727
  4. Victor Yassuda; Fernandes, Mónica T; De Sousa-Coelho, Ana Luísa. "Perfil de expressão dos genes Tribbles no cancro do cólon e reto: pistas para investigações futuras/ Expression profile of Tribbles genes in colon and rectal cancer: clues for future research.". UALGORITMO 5 1 (2023): 25-29.
    Open access • Published
  5. Telmo A. Catarino; Ivette Pacheco-Leyva; Faiza Al-Dalali; Marinella N. Ghezzo; Mónica T. Fernandes; Telma Costa; Nuno R. dos Santos. "Cdkn2a inactivation promotes malignant transformation of mouse immature thymocytes before the ß-selection checkpoint". Experimental Hematology (2022): https://doi.org/10.1016/j.exphem.2022.10.001.
    10.1016/j.exphem.2022.10.001
  6. Apolónio, Joana Dias; Dias, João S.; Fernandes, Mónica Teotónio; Komosa, Martin; Lipman, Tatiana; Zhang, Cindy H.; Leão, Ricardo; et al. "THOR is a targetable epigenetic biomarker with clinical implications in breast cancer". Clinical Epigenetics 14 1 (2022): http://dx.doi.org/10.1186/s13148-022-01396-3.
    10.1186/s13148-022-01396-3
  7. Malho Guedes, Anabela; Calças Marques, Roberto; Ribeiro, Brigitte; Fernandes, Mónica T.; Faísca, Marília; Silva, Ana Paula; Bragança, José; Rodrigues, Anabela. "Peritoneal Protein Loss, Inflammation, and Nutrition: Refuting Myths". Frontiers in Medicine 9 (2022): http://dx.doi.org/10.3389/fmed.2022.884061.
    Published • 10.3389/fmed.2022.884061
  8. Ribeiro, Brigitte; Malho Guedes, Anabela; Fernandes, Mónica; Faísca, Marília; Calças Marques, Roberto; Silva, Ana; Bragança, José; Rodrigues, Anabela; Krediet, Raymond. "MO697: FGF-21 Correlates with Overhydration: Is There a Role for Peritoneal GLUT-1?". Nephrology Dialysis Transplantation 37 Supplement (2022): http://dx.doi.org/10.1093/ndt/gfac078.034.
    Published • 10.1093/ndt/gfac078.034
  9. Malho Guedes, Anabela; Calças Marques, Roberto; Ribeiro, Brigitte; Fernandes, Mónica; Faísca, Marília; Silva, Ana; Bragança, José; Rodrigues, Anabela. "MO688: Peritoneal Protein Clearance, Inflammation, Nutrition and Overhydration in PD Patients: Looking for the Culprit". Nephrology Dialysis Transplantation 37 Supplement (2022): http://dx.doi.org/10.1093/ndt/gfac078.025.
    Published • 10.1093/ndt/gfac078.025
  10. Pimenta, Jorge M.B.G.A.; Pires, Virgínia M.R.; Nolasco, Sofia; Castelo-Branco, Pedro; Marques, Carla C.; Apolónio, Joana; Azevedo, Rita; et al. Corresponding author: Fernandes, Mónica T. "Post-transcriptional silencing of Bos taurus prion family genes and its impact on granulosa cell steroidogenesis". Biochemical and Biophysical Research Communications 598 (2022): 95-99. http://dx.doi.org/10.1016/j.bbrc.2022.02.012.
    Published • 10.1016/j.bbrc.2022.02.012
  11. Mónica T. Fernandes; Victor Yassuda; José Bragança; Wolfgang Link; Bibiana I. Ferreira; Ana Luísa De Sousa-Coelho. "Tribbles Gene Expression Profiles in Colorectal Cancer". Gastrointestinal Disorders (2021): https://www.mdpi.com/2624-5647/3/4/21.
    10.3390/gidisord3040021
  12. Fernandes, Mónica T; Pacheco-Leyva, Ivette; Nuno Alexandre Pinto Rodrigues dos Santos. "How leukemic cells manipulate normal cells for their own benefit - opportunities for new therapies? (article in portuguese)". UAlgoritmo 3 2 (2021): 28-32.
    Open access • Published
  13. Fernandes, Mónica T; Calado SM; Mendes-Silva, Leonardo; Bragança J. "CITED2 and the modulation of the hypoxic response in cancer". World Journal of Clinical Oncology 11 5 (2020): 260-274.
    Open access • Published
  14. Fernandes, Mónica T.; Caroço, Lara S.; Pacheco-Leyva, Ivette; dos Santos, Nuno R.. "NF-kB-dependent RANKL expression in a mouse model of immature T-cell leukemia". Biochemical and Biophysical Research Communications 510 2 (2019): 272-277. http://dx.doi.org/10.1016/j.bbrc.2019.01.089.
    10.1016/j.bbrc.2019.01.089
  15. Ghezzo MN; Fernandes MT; Pacheco-Leyva I; Rodrigues PM; Machado RS; Araújo MAS; Kalathur RK; et al. "FoxN1-dependent thymic epithelial cells promote T-cell leukemia development.". Carcinogenesis (2018): http://europepmc.org/abstract/med/30256907.
    10.1093/carcin/bgy127
  16. Fernandes MT; Dejardin E; Santos NR. "Context-dependent roles for lymphotoxin-ß receptor signaling in cancer development.". (2016): http://europepmc.org/abstract/med/26923876.
    10.1016/j.bbcan.2016.02.005
  17. Fernandes, Mónica. "Lymphotoxin-ß receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype". British Journal of Haematology (2015):
    10.1111/bjh.13760
  18. Boutaffala, L; Bertrand, M J M; Remouchamps, C; Seleznik, G; Reisinger, F; Janas, M; Bénézech, C; et al. "NIK promotes tissue destruction independently of the alternative NF-kB pathway through TNFR1/RIP1-induced apoptosis". Cell Death & Differentiation 22 12 (2015): 2020-2033. http://dx.doi.org/10.1038/cdd.2015.69.
    Published • 10.1038/cdd.2015.69
  19. Dos Santos NR; Ghezzo MN; da Silva RC; Fernandes MT. "NF-kB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells.". (2010): http://europepmc.org/abstract/med/24281204.
    10.3390/cancers2041838
Magazine article
  1. Fernandes, Mónica T. "Highlights COVID19 - "Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection"", LIFESAVING, 2021, http://www.chualgarve.min-saude.pt/wp-content/uploads/sites/2/2021/04/Highlights-vol2-n4.pdf.
Online resource
  1. Fernandes, Mónica T. Topical relief of musculoskeletal pain (article in portuguese). 2020. https://www.silviafernandes.pt/blog.
Thesis / Dissertation
  1. Fernandes, Mónica T. "Lymphotoxin-beta Receptor and RANK Signaling in TEL-JAK2-induced T-Cell Leukemia". PhD, Universidade do Algarve - Campus de Gambelas, 2015. http://hdl.handle.net/10400.1/8849.
  2. Fernandes, Mónica T. "The Role of Lymphotoxin-beta Receptor Signaling in T-Cell Acute Lymphoblastic Leukemia Development". Master, Universidade do Algarve - Campus de Gambelas, 2010. http://hdl.handle.net/10400.1/2407.