???global.info.a_carregar???
Isabel Sofia Dias da Silva. Concluiu o(a) Doutoramento em Ciências Biomédicas em 2018/05/07 pelo(a) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Mestrado em Genética Molecular Comparativa e Tecnológica em 2010/02/04 pelo(a) Universidade de Trás-os-Montes e Alto Douro, Licenciatura em Genética e Biotecnologia em 2008/07/09 pelo(a) Universidade de Trás-os-Montes e Alto Douro e Postgraduate Certificate em ISN advanced School 2017 em 2017/08/24 pelo(a) International Society for Neurochemistry. É Professor Visitante no(a) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar. Publicou 19 artigos em revistas especializadas. Possui 2 capítulo(s) de livros. Possui 1 patente(s) registada(s). Organizou 3 evento(s). Participou em 1 evento(s). Orientou 2 dissertação(ões) de mestrado e coorientou 1. Coorientou 2 trabalho(s) de conclusão de curso de licenciatura/bacharelato. Recebeu 15 prémio(s) e/ou homenagens. Participa e/ou participou como Bolseiro de Doutoramento em 1 projeto(s), Bolseiro de Investigação em 2 projeto(s), Investigador em 2 projeto(s) e Outra em 1 projeto(s). Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Ciências da Saúde, Ciências Médicas e da Saúde com ênfase em Medicina Básica, Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Farmacologia e Farmácia, Ciências Médicas e da Saúde com ênfase em Medicina Clínica com ênfase em Neurologia Clínica, Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Neurociências, Ciências Médicas e da Saúde com ênfase em Ciências da Saúde com ênfase em Cuidados de Saúde e Serviços, Ciências Naturais com ênfase em Ciências Biológicas, Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Biologia Molecular, Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Biologia, Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Bioquímica e Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Fisiologia. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Farmacologia; Receptores purinérgicos; ATP; Adenosina; Bexiga hiperactiva; tratamento; Tratamento; Purinas; Urina; Neurociências; Urologia; Ciência básica; Genética; Biomarcadores; Saúde; .
Read full resume ↓
Identification

Personal identification

Full name
Isabel Sofia Dias da Silva

Citation names

  • Silva, Isabel
  • Silva, I

Author identifiers

Ciência ID
D415-AE23-AE23
ORCID iD
0000-0001-7244-4792
Researcher Id
AAD-8548-2020

Addresses

  • Rua das Cavadas, nº489, Esprela, 4785-162, Bougado, Trofa, Portugal (Personal)

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Health Sciences - Health Care Sciences and Services
  • Natural sciences - Biological Sciences
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Basic Medicine - Physiology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2017 - 2021
Concluded
 Técnico de Segurança no Trabalho (Outros)
Major in Segurança no Trabalho
CICCOPN, Portugal
 Aprovado
2014/09/14 - 2018/05/07
Concluded
 Ciências Biomédicas (Doutoramento)
Major in Farmacologia, Neurociências, Urologia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Targeting the purinome to control hyperactivity of the human urinary bladder " (THESIS/DISSERTATION)
 Aprovado
2017/08/17 - 2017/08/24
Concluded
 ISN advanced School 2017 (Postgraduate Certificate)
International Society for Neurochemistry, Switzerland
 Approved
2016 - 2016
Concluded
 Certificado de Investigação Clínica – nível I (Outros)
Major in Investigação Clinica
Universidade de Aveiro, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Aprovado
2016 - 2016
Concluded
 Certificado de Competências Pedagógicas (CCP) (Outros)
Instituto do Emprego e Formação Profissional, Portugal
 Aprovado
2008/09 - 2010/02/04
Concluded
 Genética Molecular Comparativa e Tecnológica (Mestrado)
Major in Genética Molecular, Genética Comparativa, Biotecnologia
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Repercussão funcional da expressão dos receptores A2A, NK1 e M3 em várias subpopulações celulares no plexo mioentérico de íleo de rato " (THESIS/DISSERTATION)
 17
2010 - 2010
Concluded
 Ciência em animais de laboratório - FELASA tipo C (Outros)
Direcção-Geral de Alimentação e Veterinária, Portugal

Universidade do Porto, Portugal
2004/09 - 2008/07/09
Concluded
 Genética e Biotecnologia (Licenciatura)
Major in Genética , Biotecnologia
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Importância das taquicininas na neuromodulação purinérgica no plexo mioentérico de íleo de rato " (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2019/01/01 - 2021/06/30 Contracted Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2018/05/07 - 2018/12/31 Postdoc (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008/09/01 - 2018/05/08 Researcher (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/07/01 - 2008/07/01 Research Trainee (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2022/10/01 - Current Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 - 2022 Visiting Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010/02/06 - 2010/05/31 Invited Assistant (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Projects

Grant

Designation Funders
2018/06/01 - 2018/12/31 Efeito neuromodulador dos agonistas B3 na bexiga hiperactiva: Papel da libertação retrógada de adenosina
BI|UID/BIM/4308/2016|MEDINUP
Research Fellow
Universidade do Porto, Portugal
Concluded
2018/06 - 2018/12 Efeito neuromodulador dos agonistas B3 na bexiga hiperactiva: Papel da libertação retrógada de adenosina
BI|UID/BIM/4308/2016|MEDINUP
 N/A
2013/11/01 - 2017/11 TARGETING THE PURINOME TO CONTROL HYPERACTIVITY OF THE HUMAN URINARY BLADDER
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F888552%F2012/PT
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2010/10/02 - 2013/10/02 Pathophysiological role of purines (ATP and adenosine) in the human bladder hyperactivity
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/104369/PT
Research Fellow
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Concluded

Contract

Designation Funders
2022/06 - Current Purinas como biomarcadores urinários e alvos terapêuticos na isquemia/reperfusão da bexiga em doentes com obstrução urinária e hiperatividade do detrusor
2022.10707.PTDC
Researcher
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Ongoing
2019/01/01 - Current Stroke in translation: Biomarkers for diagnosis and management of acute ischemic stroke
POCI-01-0145-FEDER-031674
Researcher
Centro Hospitalar Universitário do Porto EPE, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Institute for Research and Innovation in Health
LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/06/01 - 2021 Stroke Etiology: from thrombi to easy assessable Fluid bIomarkers
SOFIA//DEFI approved
Researcher
Centro Hospitalar Universitário do Porto EPE, Portugal
 Centro Hospitalar Universitário do Porto EPE
Ongoing
2019/01 - 2021 Stroke in translation: Biomarkers for diagnosis and management of acute ischemic stroke
POCI-01-0145-FEDER-031674
 Fundação para a Ciência e a Tecnologia
2019 - 2021 CRISPR/Cas9 TTR gene editing conjugated lipid nanoparticles, as a tool for contitional TTR KO mice, in CSF and Sera independently
Intellia Therapeutics Inc, Estados Unidos
Other
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Intellia Therapeutics Inc
Ongoing
2011/01/01 - 2013/12/31 Strategic Project - UI 215 - 2011-2012
PEst-OE/SAU/UI0215/2011
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal

Centro Hospitalar Universitário de Santo António, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/09/01 - 2010/02/04 Neuromodulação purinérgica no plexo mioentérico de íleo de rato
FEDER funding, PTDC/CVT/74462/2006
UMIB-215/94
UMIB-215/94
Researcher
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 Associação para a Inovação e Desenvolvimento da FCT

Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica
Concluded

Other

Designation Funders
2022/05 - Current EPIRaft - Contribuição da reorganização das membranas e jangadas lipídicas para a fisiopatologia da epilepsia mesial temporal com esclerose do hipocampo (MTLE-HS): relação com o tratamento com dieta cetogénica
PTDC/SAU- PUB/28311/2017
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2020/09/08 - Current Implicações Médico-Legais do Covid-19 na população portuguesa
Covid-19
Supervisor
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Ongoing
2012/09/06 - 2013/07/31 Hábitos do consumo de paracetamol na população portuguesa
Paracetamol
Supervisor
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Concluded
Outputs

Publications

Book chapter
  1. Silva, Isabel; Silva-Ramos, Miguel; Ferreirinha, Fátima; Faria, Miguel; Paulo Correia-de-Sá. "Overactive Bladder (OAB): Is There a Place for Drugs Targeting the Purinergic Cascade?". In Overactive Bladder (OAB): Prevalence, Risk Factors and Management, edited by Ed. E. Larson, 127-156. United States: Nova Science Publishers, 2016.
    Published
  2. Silva, Isabel; Silva-Ramos, Miguel; Magalhães-Cardoso, Teresa; Faria, Miguel; Paulo Correia-de-Sá. "Urinary Bladder Disorders: Is Adenosine Friend or Foe?". In Adenosine Receptors: Pharmacology, Functions and Therapeutic Aspects, edited by Ed. K. Warrick. United States: Nova Science Publishers, 2015.
    Published
Conference abstract
  1. Silva, Diogo; Silva, Isabel; Magalhães-Cardoso, M. Teresa; Costa, Ana Filipa; Moreira, Sílvia; Correia-de-Sá, Paulo. "ß3 adrenoceptor-mediated inhibition of the rat urinary bladder function involves activation of the EPAC/PKC/ENT1 pathway downstream cyclic AMP production". Paper presented in Encontro de Investigação Jovem (IJUP), 2019.
  2. Silva, Isabel; Costa, AF; Moreira, Sílvia; Ferreirinha, F; Magalhães-Cardoso, MT; Calejo, I; Silva-Ramos, Miguel; et al. "Downmodulation of cholinergic neurotransmission by ß3-adrenoceptor agonists depends on adenosine release and cyclic AMP activation of the exchange protein EPAC in the human rat urinary bladder.". Paper presented in 42nd FEBS CONGRESS – FROM MOLECULES TO CELLS AND BACK. JERUSALEM, ISRAEL, 2017.
    Published
  3. Silva, Isabel; Costa, AF; Ferreirinha, F; Magalhães-Cardoso, MT; Calejo, Isabel; Silva-Ramos, Miguel; Correia-de-Sá, P; et al. "Adenosine release and A1 receptors activation mediate the inhibitory effect of ß3-adrenoceptors in the human and rat urinary bladder.". Paper presented in XIX NATIONAL CONGRESS OF BIOCHEMISTRY. GUIMARÃES, PORTUGAL, 2016.
    Published
  4. Timóteo, MA; Costa, AF; Vieira, Catia; Silva, Isabel; Correia-de-Sá, Paulo; Vieira, C; Silva, I; Correia-de-Sá, P.. "Complex roles of muscarinic receptors subtypes in the bladder of urethane-anaesthetized male Wistar rats.". Paper presented in 5. IJUP16 - 9º ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO. PORTO, PORTUGAL, 2016.
    Published
  5. Vieira, C.; Magalhães-Cardoso, M.T.; Ferreirinha, F.; Silva, I.; Dias, A.; Correia-de-Sá, P.. "Neuronal to non-neuronal shift of purine resources in the tripartite myenteric synapse of postinflammatory ileitis". 2015.
    Published • 10.1016/j.autneu.2015.07.021
  6. Silva, Isabel; Ferreirinha, F; Silva-Ramos, Miguel; Correia-de-Sá, P. "Activation of UDP-sensitive P2Y6 receptors may cause human bladder overactivity indirectly by stimulating ATP release from the urothelium". 2014.
    Published • 10.1111/bcpt.12259
  7. Silva, Isabel; Timóteo, MA; Correia, J; Ferreirinha, F; Silva-Ramos, Miguel; Sévigny, J; Correia-de-Sá, P; et al. "P2Y6-induced release of ATP from the urothelium exerts a dual role in the human urinary bladder". Paper presented in 2nd Joint Meeting of the International Society for Autonomic Neuroscience and the European Federation of Autonomic Societies, with participation of the German Autonomic Society and the LOEWE Research Focus Non-neuronal Cholinergic Systems (ISAN/EFAS 2013), 2013.
    Published
  8. Duarte-Araújo, Margarida; Marques, P; Vieira, Catia; Silva, Isabel; Magalhães-Cardoso, MT; Correia-de-Sá, P.. "Adenosine modulates its own release through activation of A2A receptors on myenteric cholinergic nerve terminals of the rat ileum". 2012.
    Published • 10.1111/j.1476-5381.1994.tb14777.x
  9. Marques, Patricia; Silva, Isabel; Vieira, Catia; Duarte-Araújo, Margarida; Magalhães-Cardoso, MT; Correia-de-Sá, P. "M3- and NK1-receptor facilitation of [3H]-acetylcholine release from myenteric motoneurons depends on extracellular adenosine accumulation acting on prejunctional A2A receptors". 2012.
    Published
  10. Silva-Ramos, Miguel; Silva, Isabel; Timóteo, MA; Carneiro, Inês; Vieira, Catia; Silva, Nuno; Correia-de-Sá, P. "UDP-sensitive P2Y6 receptors play a dual role in the human urinary bladder indirectly via the release of ATP from urothelium". 2012.
    Published
  11. Silva, I.; Marques, P.; Vieira, C.; Ferreirinha, F.; Magalhães-Cardoso, T.; Duarte-Araújo, M.; Correia-de-Sá, P.. "Amplification of cholinergic neurotransmission by adenosine released from Interstitial Cells of Cajal at a tripartite myenteric synapse of the rat ileum". Paper presented in ISAN2011, 2011.
    Published • 10.1016/j.autneu.2011.05.078
  12. Silva, Isabel; Correia, J; Ferreirinha, F; Magalhães-Cardoso, MT; Silva-Ramos, M; Sévigny, J; Correia-de-Sá, P; et al. "Bladder overactivity due to global impairment of ecto-NTPDases in humans with lower urinary tract disorders exhibiting unbalanced ATP / adenosine formation". Paper presented in 7TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) / 22ND SYMPOSIUM OF THE AMERICAN AUTONOMIC SOCIETY (AAS), BÚZIOS, BRAZIL, 2011.
    Published • 10.1007/s10286-011-0138-2
  13. Marques, Patricia; Silva, Isabel; Vieira, Catia; Ferreirinha, F; Magalhães-Cardoso, MT; Duarte-Araújo, Margarida; Correia-de-Sá, Paulo. "Interstitial cells of Cajal control cholinergic neurotransmission in the tripartite myenteric synapse by releasing adenosine". 2011.
    Published
  14. Silva-Ramos, Miguel; Silva, Isabel; Duarte-Araújo, Margarida; Magalhães-Araújo, T; Lafuente-De-Carvalho, J.M.; Correia-de-Sá, Paulo. "Loss of balance between excitatory P2X3 and inhibitory A1 receptors contribute to cholinergic hyperactivity in the obstructed human bladder". 2010.
    Published • 10.1111/j.1742-7843.2010.00599.x
  15. Silva, Isabel; Fernandes, D; Ferreirinha, F; Vieira, Catia; Duarte-Araújo, M; Correia-de-Sá, P. "Crosstalk between excitatory A2A, NK1 and M3 receptors on a tripartite myenteric synapse". 2010.
    Published • 10.1111/j.1742-7843.2010.00600.x
  16. Silva, Isabel; Duarte-Araújo, M; Fernandes, D; Ferreirinha, F; Vieira, C; Correia-de-Sá, P. "Relationship between of A2A, NK1 and M3 receptors on a tripartite". 2010.
    Published • 10.1007/s11302-010-9187-6
  17. Silva, Isabel; Duarte-Araújo, Margarida; Fernandes, Dominique; Ferreirinha, Fátima; Vieira, Cátia; Correia-de-Sá, Paulo. "Tripartite myenteric synapse: crosstalk between excitatory A2A, NK1 and M3 receptors". Paper presented in Purines 2010, Tarragona-Barcelona, 2010.
    Published
  18. Silva, I.; Duarte-Araújo, M.; Timóteo, M.A.; Magalhães-Cardoso, M.T.; Faria, M.; Silva-Ramos, M.; LaFuente-de-Carvalho, J.-M.; Correia-de-Sá, P.. "Sustained P2X3 facilitation of acetylcholine release contributes to bladder hyperactivity in humans with benign prostatic hyperplasia". Paper presented in 6th Congress of the International Society for Autonomic Neuroscience ISAN 2009, 2009.
    Published • 10.1016/j.autneu.2009.05.030
  19. Silva, Isabel; Vieira, Catia; Ferreirinha, F.; Duarte-Araújo, M.; P., Correia- De-Sa; Ferreirinha, F; Duarte-Araújo, Margarida; Correia-de-Sá, P. "Cross talk between facilitatory adenosine A2A, Tachykinin NK1 and Muscarinic M3 receptors in the rat Mynteric plexus: on the role of Capsaicin-sensitive Tachykinergic neurons". Paper presented in 11th Meeting of the Portuguese Society for Neuroscience, 2009.
    Published • 10.3389/conf.neuro.01.2009.11.149
  20. Duarte-Araújo, Margarida; Silva, Isabel; Vieira, Catia; Marques, P.; Ferreirinha, F; Magalhães-Cardoso, MT; Correia-de-Sá, Paulo. "On the role of adenosine (A2A) tonus and cross talk with NK1 and M3 receptors regulating acetylcholine release from myenteric neurons of the rat ileum". Paper presented in 6th Congress of the International Society for Autonomic Neuroscience ISAN 2009, 2009.
    Published
  21. Duarte-Araújo, M; Silva, Isabel; Vieira, Catia; Marques, Patricia; Almeida, M; Correia-de-Sá, Paulo. "Tachykinergic control of acetylcholine release from myenteric neurons requires high levels of endogenous adenosine activating A2A receptors". Paper presented in Purines 2008 Meeting 29 June – 2 July 2008, Copenhagen, Denmark, 2008.
    10.1007/s11302-008-9116-0
Conference poster
  1. Silva, Isabel; Magalhães-Cardoso, M. T.; Ferreirinha, F; Moreira, Sílvia; Costa, Ana Filipa; Silva, Diogo; Vieira, Cátia; Silva-Ramos, Miguel. "ß3-adrenoceptor inhibition of cholinergic bladder nerves requires retrograde adenosine release triggered by EPAC/PKC/ENT1 pathway in the human and rat detrusor". Paper presented in 26th Meeting of the EAU Section of Urological Research (ESUR19)., 2019.
  2. Silva, Isabel; Costa, Ana Filipa; Moreira, Sílvia; Ferreirinha, Fátima; Magalhães-Cardoso, Maria Teresa; Calejo, Isabel; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "Beta3-adrenoceptors inhibit cholinergic neurotransmission in the bladder indirectly via ADO release and A1 receptor activation". Paper presented in ISN-ENS 2017 meeting, 2017.
    10.1111/jnc.14093
  3. Silva, I; Sousa, Raquel; Viais, Ricardo; Vieira, Cátia; Jiménez, M; Correia-de-Sá, P; Silva, Isabel; et al. "Muscarinic receptors and NO differentially modulate the release of ACh and ATP in the myenteric plexus of the mouse colon". Paper presented in IJUP17 – 10º ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO, 2017.
  4. Vieira, Catia; Magalhães-Cardoso, MT; Ferreirinha, F; Silva, I; Dias, AS; Correia-de-Sá, P.. "Neuronal and non-neuronal shift of purine in the tripartite myenteric synapse of post inflammatory ileitis". Paper presented in 7. 9TH MEETING OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN 2015) in conjunction with FEDERATION OF EUROPEAN AUTONOMIC SOCIETIES (EFAS), AMERICAN AUTONOMIC SOCIETY (AAS), JAPAN SOCIETY OF NEUROVEGETATIVE RESEARCH (JSNR). STRESA, ITALY, 2015.
  5. Silva, I; Magalhães-Cardoso, MT; Correia, J; Ferreirinha, F; Faria, M; Silva-Ramos, M; Sévigny, J; Correia-de-Sá, P; Silva, Isabel. "Ecto-NTPDases, the ATP metabolizing enzymes, are critical determinants of cholinergic inhibition by adenosine in the human urinary bladder.". Paper presented in 25TH MEETING OF THE INTERNATIONAL SOCIETY FOR NEUROCHEMISTRY, 13TH APSN, 35TH ANS MEETING. CAIRNS, AUSTRALIA, 2015.
  6. Silva, I; Magalhães-Cardoso, MT; Correia, J; Ferreirinha, F; Faria, M; Silva-Ramos, M; Sévigny, J; Correia-de-Sá, P. "Adenosine A1 receptor-mediated inhibition of cholinergic neurotransmission in the human urinary bladder depends on tissue distribution of ecto-nucleotidases.". Paper presented in XIV MEETING PORTUGUESE SOCIETY FOR NEUROSCIENCES. PÓVOA DE VARZIM, PORTUGAL, 2015.
  7. Timóteo, MA; Neves, L; Fernandes, M; Silva, I; Correia-de-Sá, P; Oliveira, Laura. "Unravelling the role of ATP on neuromuscular transmission in an experimental model of autoimmune Myasthenia gravis (EAMG)". Paper presented in IJUP15 - 8º ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO. PORTO, PORTUGAL, 2015.
  8. Silva, I; Ferreirinha, F; Silva-Ramos, Miguel; Correia-de-Sá, P; Silva, Isabel; Ferreirinha, Fatima; Silva-Ramos, Miguel; Correia-de-Sa, Paulo. "Overactive human bladder: Tandem activation of P2Y6 and P2X3 purinoceptors operated by ATP released from the urothelium via pannexin-1 hemichannels.". Paper presented in PURINES 2014: NUCLEOTIDES, NUCLEOSIDES AND NUCLEOBASES. INTERNATIONAL CONFERENCE ON SIGNALLING, DRUGS AND TARGETS, BONN, GERMANY, 2014.
  9. Noronha-Matos, JB; Calejo, Isabel; Magalhães-Cardoso, MT; Silva, I; Ferreirinha, F.; Rocha, Rui; Marinhas, José; et al. "Adult bone marrow stromal cells expressing ecto-NTPDase3 may be a novel therapeutic target for defective osteogenesis and bone mineralization.". Paper presented in PURINES 2014: NUCLEOTIDES, NUCLEOSIDES AND NUCLEOBASES. INTERNATIONAL CONFERENCE ON SIGNALLING, DRUGS AND TARGETS, BONN, GERMANY, 2014.
  10. Vieira, C; Magalhães-Cardoso, MT; Ferreirinha, F; Silva, I; Dias, AS; Pelletier, J; Sévigny, J; Correia-de-Sá, P. "Feed-forward inhibition of CD73 and upregulation of adenosine deaminase underlie adenosine neuromodulation failure in the chronic inflamed ileum.". Paper presented in PURINES 2014: NUCLEOTIDES, NUCLEOSIDES AND NUCLEOBASES. INTERNATIONAL CONFERENCE ON SIGNALLING, DRUGS AND TARGETS, BONN, GERMANY, 2014.
  11. Silva, I; Ferreirinha, F; Silva-Ramos, Miguel; Correia-de-Sá, P. "Activation of UDP-sensitive P2Y6 receptors may cause human bladder overactivity indirectly by stimulating ATP release from the urothelium.". Paper presented in 17th WORLD CONGRESS OF BASIC & CLINICAL PHARMACOLOGY, CAPE TOWN, SOUTH AFRICA, 2014.
  12. Oliveira, Laura; Costa, Maria Adelina; Noronha-Matos, JB; Silva, I; Ambiel, CR; Corrado, AP; Alves-do-Pardo, W; Correia-de-Sá, P. "Presynaptic M1 and A2A receptors play roles in facilitatory effect caused by methylprednisolone in neuromuscular transmission". Paper presented in 45th BRAZILIAN CONGRESS ON PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, RIBEIRÃO PRETO, BRAZIL, 2013.
  13. Silva, I; Correia, J; Ferreirinha, F; Silva-Ramos, Miguel; Sévigny, J; Correia-de-Sá, P. "Adenosine, acting on A1 receptors, negatively modulates acetylcholine and ATP release from cholinergic nerves of the bladder of patients with benign prostatic obstruction". Paper presented in XIII REUNIÃO DA SOCIEDADE PORTUGUESA DE NEUROCIÊNCIAS. LUSO. PORTUGAL, 2013.
  14. Silva-Ramos, Miguel; Silva, I; Timóteo, MA; Carneiro, Inês; Vieira, Catia; Silva, Nuno; Monteiro, Diogo; et al. "UDP-Sensitive P2Y6 receptors play a dual role in the human urinary bladder indirectly via the release of ATP from urothelium.". Paper presented in 42nd ANNUAL MEETING OF THE INTERNATIONAL CONTINENCE SOCIETY (ICS). BEIJING. CHINA, 2012.
  15. Duarte-Araújo, M; Marques, Patricia; Vieira, Catia; Silva, I; Magalhães-Cardoso, MT; Correia-de-Sá, P. "Adenosine modulates its own release through activation of A2A receptors on myenteric cholinergic nerve terminals of the rat ileum.". Paper presented in JOINT INTERNATIONAL NEUROGASTROENTEROLOGY AND MOTILITY MEETING. BOLOGNA. ITALY., 2012.
  16. Silva, I; Marques, Patricia; Vieira, Catia; Duarte-Araújo, Margarida; Ferreirinha, F; Magalhães-Cardoso, MT; Correia-de-Sá, P. "M3- and NK1-receptors facilitation of [3H]-acetylcholine release from myenteric motoneurons depends on extracellular adenosine accumulation acting on prejunctional A2A receptors.". Paper presented in JOINT INTERNATIONAL NEUROGASTROENTEROLOGY AND MOTILITY MEETING. BOLOGNA. ITALY., 2012.
  17. Marques, Patrícia; Silva, I; Vieira, Catia; Ferreirinha, F; Magalhães-Cardoso, MT; Duarte-Araújo, M; Correia-de.Sá, P. "Muscarinic neuromuscular transmission amplification by adenosine released from interstitial cells of Cajal of the rat ileum.". Paper presented in VIIth INTERNATIONAL SYMPOSIUM ON: INTERSTITIAL CELLS OF CAJAL. FLORENCE. ITALY., 2012.
  18. Silva, I; Timóteo, MA; Carneiro, Inês; Vieira, Catia; Silva, Nuno; Marinhas, José; Monteiro, Diogo; et al. "Dual role of UDP-sensitive P2Y6 receptors in the urothelium and cholinergic nerves of the human urinary bladder.". Paper presented in PURINE 2012: ADENINE NUCLEOSIDES AND NUCLEOTIDES IN BIOMEDICINE. FUKUOKA. JAPAN., 2012.
  19. Silva, I; Magalhães-Cardoso, MT; Ferreirinha, F; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "P2X receptors -induced bladder overactivity may be partially counteracted by adenosine activating A1 receptors in patients with beningn prostatic obstruction.". Paper presented in 5as JORNADAS DE BIOLOGIA "ALTERAÇÕES CLIMÁTICAS". VILA REAL. PORTUGAL., 2011.
  20. Silva, I; Marques, Patricia; Vieira, Catia; Ferreirinha, Fátima; Magalhães-Cardoso, MT; Duarte-Araújo, Margarida; Correia-de-Sá, Paulo. "Amplification of cholinergic neurotransmission by adenosine released from interstitial Cells of Cajal at a tripartite myenteric synapse of the rat Ileum.". Paper presented in 7TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) / 22ND SYMPOSIUM OF THE AMERICAN AUTONOMIC SOCIETY (AAS), BÚZIOS, BRAZIL, 2011.
  21. Silva-Ramos, Miguel; Silva, I; Magalhães-Cardoso, MT; Ferreirinha, F; Correia-de-Sá, P. "Slowing down adenosine formation from release ATP contributes to cholinergic nerve hyperactivity in the obstructed human bladder.". Paper presented in 41st ANNUAL MEETING OF THE INTERNATIONAL CONTINENCE SOCIETY (ICS), GLASGOW, UNITED KINGDOM, 2011.
  22. Silva, I; Marques, Patricia; Vieira, Catia; Ferreirinha, F; Magalhães-Cardoso, MT; Duarte-Araújo, Margarida; Correia-de-Sá, Paulo. "Interstitial cells of Cajal control cholinergic neurotransmission in the tripartite myenteric synapse by releasing adenosine". Paper presented in 23RD BIENNAL MEETING - ISN-ESN. ATHENS, GREECE, 2011.
  23. Oliveira-Monteiro, Nadia; Silva, I; Ferreirinha, MF; Nogueira-Marques, Silvia; Bragança, Bruno; Duarte-Araújo, Margarida; Fontes-Sousa, AP; Correia-de-Sá, P. "Neonatal depletion of pepetidergic nerve fibers reduces muscarinic receptor-mediated effects in the ileum, but not in atria of adult Wistar rats". Paper presented in 4th MEETING OF YOUNG RESEARCHERS AT UP. PORTO, PORTUGAL, 2011.
  24. Silva, I; Fernandes, Dominique; Ferreirinha, F; Vieira, Catia; Marques, Patricia; Duarte-Araújo, Margarida; Correia-de-Sá, Paulo. "Synergism between NK1 and A2A, but not with M3, receptors to control ACh release at a tripartite myenteric synapse". Paper presented in XVII CONGRESSO NACIONAL DE BIOQUIMICA. PORTO, PORTUGAL, 2010.
  25. Silva-Ramos, Miguel; Oliveira, Olga; Duarte-Araújo, Margarida; Silva, I; Correia-de-Sá, P. "ATP: A novel urinary biomarker of detrusor overactivity.". Paper presented in JOINT ANNUAL MEETING OF THE INTERNATIONAL CONTINENCE SOCIETY (ICS) AND INTERNATIONAL UROGYNECOLOGICAL ASSOCIATION (IUGA). TORONTO, CANADA, 2010.
  26. Silva, I; Fernandes, Dominique; Ferreirinha, F; Vieira, Catia; Duarte-Araújo, Margarida; Correia-de-Sá, P. "Crosstalk between excitatory A2A, NK1 and M3 receptors on a tripartite myenteric synapse.". Paper presented in 16th WORLD CONGRESS ON BASIC AND CLINICAL PHARMACOLOGY. COPENHAGEN, DENMARK, 2010.
  27. Silva, I; Duarte-Araújo, Margarida; Fernandes, Dominique; Ferreirinha, F; Vieira, Catia; Correia-de-Sá, P. "Relationship between of A2A, NK1 and M3 receptors on a tripartite". Paper presented in PURINES 2010 - ADENINE NUCLEOSIDES AND NUCLEOTIDES IN BIOMEDICINE. TARRAGONA, SPAIN, 2010.
  28. Duarte-Araújo, Margarida; Silva, I; Vieira, Catia; Marques, Patricia; Ferreirinha, F; Magalhães-Cardoso, MT; Correia-de-Sá, Paulo. "On the role of adenosine (A2A) tonus and cross talk with NK1 and M3 receptors regulating acetylcholine release from myenteric neurons of the rat ileum.". Paper presented in 6TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE. SIDNEY, AUSTRALIA, 2009.
  29. Duarte-Araújo, Margarida; Marques, Patricia; Silva, I; Vieira, Catia; Magalhães-Cardoso, MT; Correia-de-Sá, P. "Tachykinergic neurons may be an important source of purines (ATP and Adenosine) in the myenteric plexus of the rat ileum.". Paper presented in THIRD JOINT ITALIAN - GERMAN PURINE CLUB MEETING. CAMERINO, ITALY., 2009.
  30. Marques, Patricia; Duarte-Araújo, Margarida; Silva, I; Vieira, Catia; Almeida, Marisa; Magalhães-Cardoso, MT; Correia-de-Sá, P; Silva, Isabel; P., Correia- De-Sa. "Neonatal capsaicin-treated rats have reduced extracellular purine levels in the myenteric plexus". Paper presented in 11TH MEETING PORTUGUESE SOCIETY FOR NEUROCIENCES. BRAGA, PORTUGAL, 2009.
    10.3389/conf.neuro.01.2009.11.146
  31. Marques, Patricia; Duarte-Araújo, Margarida; Silva, I; Vieira, Catia; Almeida, Marisa; Magalhães-Cardoso, MT; Correia-de-Sá, P. "Capsaicin-sensitive myenteric neurons may be an important source of purines (ATP and adenosine) in the myenteric plexus". Paper presented in IJUP09 - ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO. PORTO, PORTUGAL, 2009.
Journal article
  1. Maqueda, Joaquín J.; Giovanazzi, Alberta; Rocha, Ana Mafalda; Rocha, Sara; Silva, Isabel; Saraiva, Nadine; Bonito, Nuno; et al. "Adapter dimer contamination in sRNA-sequencing datasets predicts sequencing failure and batch effects and hampers extracellular vesicle-sRNA analysis". Journal of Extracellular Biology 2 6 (2023): http://dx.doi.org/10.1002/jex2.91.
    10.1002/jex2.91
  2. Fernandes, Sara; Sosa-Napolskij, Milaydis; Lobo, Graça; Silva, Isabel. "Relation of COVID-19 with liver diseases and their impact on healthcare systems: The Portuguese case". World Journal of Gastroenterology 29 6 (2023): 1109-1122. http://dx.doi.org/10.3748/wjg.v29.i6.1109.
    Published • 10.3748/wjg.v29.i6.1109
  3. Correia, Manuel; Silva, Isabel; Gabriel, Denis; Simrén, Joel; Carneiro, Angelo; Ribeiro, Sara; Dória, Hugo Mota; et al. "Early plasma biomarker dynamic profiles are associated with acute ischemic stroke outcomes". European Journal of Neurology 29 6 (2022): 1630-1642. http://dx.doi.org/10.1111/ene.15273.
    10.1111/ene.15273
  4. Sara Fernandes; Sanjay Kumar Singh Patel; Milaydis Sosa-Napolskij; Graça Lobo; Isabel Silva. "Impact of the COVID-19 pandemic in the Portuguese population: Consumption of alcohol, stimulant drinks, illegal substances, and pharmaceuticals". PLOS ONE (2021): https://doi.org/10.1371/journal.pone.0260322.
    10.1371/journal.pone.0260322
  5. Alexandre Dias; Isabel Silva; Inês Mendes Pinto; Luís F. Maia. "Timely and Blood-Based Multiplex Molecular Profiling of Acute Stroke". Life (2021): https://doi.org/10.3390/life11080816.
    10.3390/life11080816
  6. Silva, Isabel; Magalhães-Cardoso, M. Teresa; Ferreirinha, Fátima; Moreira, Sílvia; Costa, Ana Filipa; Silva, Diogo; Vieira, Cátia; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "ß 3 adrenoceptor-induced cholinergic bladder inhibition involves EPAC1 and PKC favoring ENT1-mediated adenosine outflow from the human and rat detrusor". British Journal of Pharmacology (2019): http://dx.doi.org/10.1111/bph.14921.
    10.1111/bph.14921
  7. Silva-Ramos, M.; Silva, I.; Faria, M.; Ferreirinha, F.; Correia-de-Sá, P.. "Activation of Prejunctional P2x2/3 Heterotrimers by ATP Enhances the Cholinergic Tone in Obstructed Human Urinary Bladders". Journal of Pharmacology and Experimental Therapeutics 372 1 (2019): 63-72. http://dx.doi.org/10.1124/jpet.119.261610.
    10.1124/jpet.119.261610
  8. Silva-Ramos, M.; Lopes, A.; Silva, D.; Silva, I; Correia-de-Sa, P.. "URINARY ATP CONCENTRATIONS ARE RELATED TO DETRUSOR PRESSURE DURING VOIDING". Neurourology and Urodynamics (2019): https://publons.com/publon/27523155/.
  9. Noronha-Matos, J. B.; Cardoso, R.; Calejo, I; Magalhaes-Cardoso, M. T.; Silva, I; Costa, M. A.; Ferreirinha, F.; et al. "Oral Communication: NTPDase3 enzyme inhibition or gene silencing rescues the osteogenic potential of post-menopausal mesenchymal stein cells (MSCs) derived from hone marrow". Purinergic Signalling (2018): https://publons.com/publon/27523158/.
  10. Vieira, Cátia; Ferreirinha, Fátima; Magalhães-Cardoso, Maria T.; Silva, Isabel; Marques, Patrícia; Correia-de-Sá, Paulo. "Post-inflammatory Ileitis Induces Non-neuronal Purinergic Signaling Adjustments of Cholinergic Neurotransmission in the Myenteric Plexus". Frontiers in Pharmacology 8 (2017): http://dx.doi.org/10.3389/fphar.2017.00811.
    10.3389/fphar.2017.00811
  11. Silva, Isabel; Costa, Ana Filipa; Moreira, Sílvia; Ferreirinha, Fátima; Magalhães-Cardoso, Maria Teresa; Calejo, Isabel; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "Inhibition of cholinergic neurotransmission by ß3-adrenoceptors depends on adenosine release and A1-receptor activation in human and rat urinary bladders". American Journal of Physiology-Renal Physiology 313 2 (2017): F388-F403. http://dx.doi.org/10.1152/ajprenal.00392.2016.
    10.1152/ajprenal.00392.2016
  12. Silva-Ramos M; Silva I; Oliveira JC; Correia-de-Sá P; Silva-Ramos, Miguel; Silva, Isabel; Oliveira, Jose Carlos; et al. "Increased urinary adenosine triphosphate in patients with bladder outlet obstruction due to benign prostate hyperplasia.". Prostate 76 15 (2016): 1353-1363. http://europepmc.org/abstract/med/27418113.
    10.1002/pros.23207
  13. Certal, Mariana; Vinhas, Adriana; Pinheiro, Ana Rita; Ferreirinha, Fátima; Barros-Barbosa, Aurora Raquel; Silva, Isabel; Costa, Maria Adelina; Correia-de-Sá, Paulo. "Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts". Cell Calcium 58 5 (2015): 518-533. http://dx.doi.org/10.1016/j.ceca.2015.08.004.
    10.1016/j.ceca.2015.08.004
  14. Silva, I.; Ferreirinha, F.; Magalhães-Cardoso, M.T.; Silva-Ramos, M.; Correia-de-Sá, P.; Silva, I; Ferreirinha, F; et al. "Blockage of UDP-sensitive P2Y6 receptors as a novel therapeutic strategy to control urine storage symptoms in men with bladder outlet obstruction". Autonomic Neuroscience 192 (2015): 56. http://dx.doi.org/10.1016/j.autneu.2015.07.010.
    Published • 10.1016/j.autneu.2015.07.010
  15. Silva-Ramos, M.; Silva, I.; Faria, M.; Magalhães-Cardoso, M. T.; Correia, J.; Ferreirinha, F.; Correia-de-Sá, P.. "Impairment of ATP hydrolysis decreases adenosine A1 receptor tonus favoring cholinergic nerve hyperactivity in the obstructed human urinary bladder". Purinergic Signalling 11 4 (2015): 595-606. http://dx.doi.org/10.1007/s11302-015-9478-z.
    10.1007/s11302-015-9478-z
  16. Silva, Isabel; Ferreirinha, Fátima; Magalhães-Cardoso, Maria Teresa; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "Activation of P2Y6Receptors Facilitates Nonneuronal Adenosine Triphosphate and Acetylcholine Release from Urothelium with the Lamina Propria of Men with Bladder Outlet Obstruction". Journal of Urology 194 4 (2015): 1146-1154. http://dx.doi.org/10.1016/j.juro.2015.05.080.
    10.1016/j.juro.2015.05.080
  17. Kelsey, Rebecca. "P2Y6 blockade might help control bladder storage symptoms". Nature Reviews Urology 12 7 (2015): 358-358. http://dx.doi.org/10.1038/nrurol.2015.134.
    10.1038/nrurol.2015.134
  18. Mendes, Cristina Eusébio; Palombit, Kelly; Vieira, Cátia; Silva, Isabel; Correia-de-Sá, Paulo; Castelucci, Patricia. "The Effect of Ischemia and Reperfusion on Enteric Glial Cells and Contractile Activity in the Ileum". Digestive Diseases and Sciences 60 9 (2015): 2677-2689. http://dx.doi.org/10.1007/s10620-015-3663-3.
    10.1007/s10620-015-3663-3
  19. Oliveira, L.; Costa, A.C.; Noronha-Matos, J.B.; Silva, I.; Cavalcante, W.L.G.; Timóteo, M.A.; Corrado, A.P.; et al. "Amplification of neuromuscular transmission by methylprednisolone involves activation of presynaptic facilitatory adenosine A2A receptors and redistribution of synaptic vesicles". Neuropharmacology 89 (2015): 64-76. http://dx.doi.org/10.1016/j.neuropharm.2014.09.004.
    10.1016/j.neuropharm.2014.09.004
  20. Silva, I.; Magalhaes-Cardoso, M. T.; Correia, J.; Ferreirinha, F.; Faria, M.; Silva-Ramos, M.; Sevigny, J.; Correia-de-Sa, P.. "ECTO-NTPdases, the ATP metabolizing enzymes, are critical determinants of cholinergic inhibition by adenosine in the human urinary". Journal of Neurochemistry 134 (2015): 152-152. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000360206300354&KeyUID=WOS:000360206300354.
  21. Silva, Isabel. "Abstracts from Purines 2014, an International Conference on Nucleotides, Nucleosides and Nucleobases, held in Bonn, Germany, from July 23–27, 2014.". (2014): http://europepmc.org/abstract/PMC/PMC4272368.
  22. Carneiro, Inês; Timóteo, M Alexandrina; Silva, Isabel; Vieira, Cátia; Baldaia, Catarina; Ferreirinha, Fátima; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "Activation of P2Y6receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium". British Journal of Pharmacology 171 14 (2014): 3404-3419. http://dx.doi.org/10.1111/bph.12711.
    10.1111/bph.12711
  23. Timóteo, M. Alexandrina; Carneiro, Inês; Silva, Isabel; Noronha-Matos, José Bernardo; Ferreirinha, Fátima; Silva-Ramos, Miguel; Correia-de-Sá, Paulo. "ATP released via pannexin-1 hemichannels mediates bladder overactivity triggered by urothelial P2Y6 receptors". Biochemical Pharmacology 87 2 (2014): 371-379. http://dx.doi.org/10.1016/j.bcp.2013.11.007.
    10.1016/j.bcp.2013.11.007
  24. Vieira, Cátia; Magalhães-Cardoso, Maria Teresa; Ferreirinha, Fátima; Silva, Isabel; Dias, Ana Sofia; Pelletier, Julie; Sévigny, Jean; Correia-de-Sá, Paulo. "Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis". Mediators of Inflammation 2014 (2014): 1-19. http://dx.doi.org/10.1155/2014/254640.
    10.1155/2014/254640
  25. Silva, I; Ferreirinha, F.; Silva-Ramos, M.; Correia-de-Sa, P.. "ACTIVATION OF UDP-SENSITIVE P2Y6 RECEPTORS MAY CAUSE HUMAN BLADDER OVERACTIVITY INDIRECTLY BY STIMULATING ATP RELEASE FROM THE UROTHELIUM". Basic & Clinical Pharmacology & Toxicology 115 (2014): 251-252. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000356300903006&KeyUID=WOS:000356300903006.
  26. Silva-Ramos, Miguel; Silva, Isabel; Oliveira, Olga; Ferreira, Sónia; Reis, Maria Júlia; Oliveira, José Carlos; Correia-de-Sá, Paulo. "Urinary ATP May Be a Dynamic Biomarker of Detrusor Overactivity in Women with Overactive Bladder Syndrome". PLoS ONE 8 5 (2013): e64696. http://dx.doi.org/10.1371/journal.pone.0064696.
    10.1371/journal.pone.0064696
  27. Silva, Renata; Carmo, Helena; Vilas-Boas, Vânia; Pinho, Paula Guedes de; Dinis-Oliveira, Ricardo Jorge; Carvalho, Félix; Silva, Isabel; et al. "Doxorubicin decreases paraquat accumulation and toxicity in Caco-2 cells". Toxicology Letters 217 1 (2013): 34-41. http://dx.doi.org/10.1016/j.toxlet.2012.11.028.
    10.1016/j.toxlet.2012.11.028
  28. Silva-Ramos, M.; Silva, I; Timoteo, M. A.; Carneiro, I; Vieira, C.; Silva, N.; Monteiro, D.; et al. "UDP-SENSITIVE P2Y6 RECEPTORS PLAY A DUAL ROLE IN THE HUMAN URINARY BLADDER INDIRECTLY VIA THE RELEASE OF ATP FROM UROTHELIUM". Neurourology and Urodynamics 31 6 (2012): 1023-1024. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000306314700231&KeyUID=WOS:000306314700231.
  29. Vieira, Cátia; Ferreirinha, Fátima; Silva, Isabel; Duarte-Araújo, Margarida; Correia-de-Sá, Paulo. "Localization and function of adenosine receptor subtypes at the longitudinal muscle – Myenteric plexus of the rat ileum". Neurochemistry International 59 7 (2011): 1043-1055. http://dx.doi.org/10.1016/j.neuint.2011.08.016.
    10.1016/j.neuint.2011.08.016
  30. Silva-Ramos, M.; Duarte-Araújo, M.; Silva, I.; Lafuente-De-Carvalho, J.M.; Correia-De-SÁ, P.. "276 ACTIVATION OF P2×1 PURINOCEPTORS FACILITATE EVOKED ACETYLCHOLINE RELEASE IN HUMAN OBSTRUCTED BLADDERS". European Urology Supplements 8 4 (2009): 189. http://dx.doi.org/10.1016/s1569-9056(09)60281-5.
    10.1016/s1569-9056(09)60281-5
  31. Silva-Ramos, M.; Duarte-Araujo, M.; Silva, I; Lafuente-De-Carvalho, J. M.; Correia-De-Sa, P.. "ACTIVATION OF P2X1 PURINOCEPTORS FACILITATE EVOKED ACETYLCHOLINE RELEASE IN HUMAN OBSTRUCTED BLADDERS". European Urology Supplements 8 4 (2009): 189-189. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000266587100274&KeyUID=WOS:000266587100274.

Intellectual property

Patent
  1. Silva-Ramos, Miguel; Correia-de-Sá, Paulo; Silva, Isabel. 2016. "ATP as a biomarker of bladder outlet obstruction". Portugal.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/02 ß3 Adrenoceptor inhibition of cholinergic neurotransmission envolves adenosine outflow via the EPAC/PKC/ENT1 pathway in the urinary bladder XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica, XVIII Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2019 Urinary ATP concentrations are related to detrusor pressure during voiding ICS2019
International Continence Society (Sweden)
2018/02 ß3-Adrenoceptor agonists indirectly modulate cholinergic neurotransmission in the urinary bladder via adenosine relaese downstream cyclic AMP activation of EPAC XVII REUNIÃO DE TOXICOLOGIA, XXXVI REUNIÃO DE FARMACOLOGIA CLÍNICA E XLVIII REUNIÃO ANUAL DA SOCIEDADE DE FARMACOLOGIA
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2017/02 ß3-adrenoceptors indirectly mediate inhibition of cholinergic neurotransmission in the rat urinary bladder by releasing adenosine via ENT1 and A1 receptors activation. IJUP17 – 10º ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO
Universidade do Porto (Porto, Portugal)
2017/02 ß3-Adrenoceptor agonists indirectly modulate cholinergic neurotransmission in the urinary bladder by releasing adenosine via ENT1 and A1 receptors activation XLVII REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXV REUNIÃO DE FARMACOLOGIA CLINICA / XVI REUNIÃO DE TOXICOLOGIA.
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2016/06 Do patients with outlet obstruction have higher urinary ATP? XIV CONGRESSO DA SOCIEDADE IBEROAMERICANA DE NEUROUROLOGIA E UROGINECOLOGIA – SINUG
Sociedade Portuguesa de Uroginecologia (Porto, Portugal)
2016/06 Fine tuning control of cholinergic nerve activity by excitatory P2X2/3 and inhibitory P2Y12 receptors in men with prostatic bladder obstruction 7º EUROPEAN CONGRESS OF PHARMACOLOGY – EPHAR 2016
EPHAR (Istambul, Turkey)
2016/05 As purinas no sistema nervoso autónomo – investigação uro-translacional: do laboratório à prática clinica VIII JORNADAS DE NEUROFISIOLOGIA
ESTSP-P.PORTO (Porto, Portugal)
2016/02 Dual role of ATP on neuromuscular transmission in Experimental Autoimmune Myasthenia Gravis IJUP16 - 9º ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO
Universidade do Porto (Porto, Portugal)
2016/02 Blockage of the P2Y6 receptor may control persistent urinary storage symptoms in patients with benign prostatic hyperplasia. XLVI REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXIV REUNIÃO DE FARMACOLOGIA CLÍNICA / XV REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2016/02 ATP as na excitatory gliotransmitter involved in maintenance of the cholinergic tone in postinflammatory ileitis. XLVI REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXIV REUNIÃO DE FARMACOLOGIA CLÍNICA / XV REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2016/02 The NTPDase3 inhibitor HN3-B3S antibody restores the osteogenic capability of the bone marrow-derived mesenchymal stem cells of postmenopausal women 10. XLVI REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXIV REUNIÃO DE FARMACOLOGIA CLÍNICA / XV REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2015/07 Overactive bladder syndrome: Evidence that urinary ATP is a dynamic biomarker of detrusor overactivity. 8TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) / 15TH MEETING OF THE EUROPEAN FEDERATION OF AUTONOMIC SOCIETIES (EFAS)
INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) (Giessen, Germany)
2015/06 Human bladder hyperactivity caused by UDP-sensitive P2Y6 receptors: on the role of ATP release from the urothelium via pannexin-1 hemichannel FIFHT BRASILIAN PURINE CLUB MEETING / II INTERNATIONAL CONGRESS OF PURINERGIC SIGNALLING IN SOUTH AMERICA
BRASILIAN PURINE CLUB (São Paulo, Brazil)
2015/02 Differential distribution of ectonucleotidases within the human urinary bladder wall restricts adenosine action to the detrusor smooth muscle layer 12. XLV REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXIII REUNIÃO DE FARMACOLOGIA CLÍNICA / XIV REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2015/02 Postinflammatory ileitis causes a shift from neuronal to non-neuronal release sites of purines in the rat tripartite myenteric synapse. 13. XLV REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXIII REUNIÃO DE FARMACOLOGIA CLÍNICA / XIV REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2015/02 Methylprednisolone rehabilitates the presynaptic facilitatory adenosine A2A receptor tonus in the neuromuscular junction of rats with experimental autoimmune Myasthenia gravis XLV REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXIII REUNIÃO DE FARMACOLOGIA CLÍNICA / XIV REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2014/02 UDP-sensitive P2Y6 receptors act in tandem with the ionotropic P2X3 purinoceptors to increase ATP release. XLIV REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXII REUNIÃO DE FARMACOLOGIA CLÍNICA / XIII REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2014/02 Inhibition of ecto-NTPDase3 promites osteogenic differentiation of human marrow stromal cells (BMSCs) mediated by P2X7 and P2Y6 receptors activation XLIV REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXII REUNIÃO DE FARMACOLOGIA CLÍNICA / XIII REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2013/07 Dual role of P2Y6 receptors in the human urinary bladder: on the role of ATP release from the urothelium. 8TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) / 15TH MEETING OF THE EUROPEAN FEDERATION OF AUTONOMIC SOCIETIES (EFAS)
INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) (Giessen, Germany)
2013/02 Activation of P2Y6 receptors plays a dual role in the human urinary bladder indirectly by releasing ATP from urothelium. XLIII REUNIÃO ANUAL DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXI REUNIÃO DE FARMACOLOGIA CLÍNICA / XII REUNIÃO DE TOXICOLOGIA.
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2013/02 Bladder overactivity caused by activation of UDP-sensitive P2Y6 receptors depends on ATP release from the urothelium via pannexin-1 hemichannels in the anaesthetized rat XLIII REUNIÃO ANUAL DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXI REUNIÃO DE FARMACOLOGIA CLÍNICA / XII REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2013/02 Role of P2X7 and A1 receptors in myenteric synaptic transmission after ischemia and reperfusion of the rat ileum. XLIII REUNIÃO ANUAL DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXXI REUNIÃO DE FARMACOLOGIA CLÍNICA / XII REUNIÃO DE TOXICOLOGIA.
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2012/06 Retrograde amplification (via A2A receptors) of transmitter efflux by adenosine release from interstitial Cells of Cajal in the tripartite myenteric synapse of the rat ileum. PURINE 2012: ADENINE NUCLEOSIDES AND NUCLEOTIDES IN BIOMEDICINE
International Society of Purines (Fukuoka, Japan)
2012/02 Adenosine mediates a positive feedback mechanism facilitating Ach release from rat myenteric motoneurons through the cross-talk between A2A, M3 and NK1 receptors 5th MEETING OF YOUNG RESEARCHERS OF U.PORTO.
Universidade do Porto (Porto, Portugal)
2012/02 Impairment of ecto-NTPDases activity leading to ATP accumulation and decreased formation of adenosine contributes to overactivity of the human bladder XLII REUNIÃO ANUAL DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXX REUNIÃO DE FARMACOLOGIA CLÍNICA / XL REUNIÃO DE TOXICOLOGIA
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2012/02 XLII REUNIÃO ANUAL DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA / XXX REUNIÃO DE FARMACOLOGIA CLÍNICA / XL REUNIÃO DE TOXICOLOGIA Adenosine facilitates its own release in the rat myenteric plexus through the activation of A2A receptors coupled to the adenylate cyclase / cyclic AMP pathway.
Sociedade Portuguesa de Farmcaologia (Lisboa, Portugal)
2011/09 Amplification of cholinergic neurotransmission by adenosine released from interstitial Cells of Cajal at a tripartite myenteric synapse of the rat Ileum 7TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (ISAN) / 22ND SYMPOSIUM OF THE AMERICAN AUTONOMIC SOCIETY (AAS)
INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (Búzios, Brazil)
2011/06 Poderá o ATP urinário desempenhar um papel como biomarcador da bexiga hiperactiva? CONGRESSO DA ASSOCIAÇÃO PORTUGUESA DE UROLOGIA 2011
(Portugal)
2011/02 Interstitial cells of Cajal regulate cholinergic neurotransmission in the rat myenteric plexus: On the role of endogenous adenosine. 4th MEETING OF YOUNG RESEARCHERS OF U.PORTO. PORTO, PORTUGAL
Universidade do Porto (Portugal)
2011/02 Adenosine release from interstitial cells of Cajal plays a key role to control cholinergic neuromuscular transmission in the tripartite myenteric synapse. XLI REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA.
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2010/10 Synergism between NK1 and A2A, but not with M3, receptors to increase cholinergic neurotransmission in a tripartite myenteric synapse. 4as JORNADAS DE BIOLOGIA - BIODIVERSIDADE.
Universidade de Trás-os-Montes e Alto-Douro (Vila Real, Portugal)
2010/10 Loss of balance between excitatory P2X3 and inhibitory A1 receptors contribute to cholinergic hyperactivity in the obstructed human bladder. 16th WORLD CONGRESS ON BASIC AND CLINICAL PHARMACOLOGY
IUPHAR (Copenhaga, Denmark)
2010/02 Interaction of purinergic, tachykinergic and muscarinic receptors on a tripartite myenteric synapse IJUP10 - ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO
Universidade do Porto (Porto, Portugal)
2010/02 ATP is a non-invasive biological urinary marker of overactive bladder syndromes IJUP10 - ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO
Universidade do Porto (Porto, Portugal)
2009/12 Physiological interactions of excitatory A2A, M3 and NK1 receptors expressed in a tripartite myenteric synapse XL REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA.
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2009/12 Tonic P2X3-mediated facilitation of acetylcholine release in patients with overactive bladder secondary to bening prostatic obstruction. XL REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2009/10 The role of capsaicin-sensitive tachykinergic neurons in the rat myenteric plexus: relationship between facilitatory adenosine A2A, tachykinin NK1, and muscarinic M3 receptors 3as JORNADAS DE BIOLOGIA: EVOLUÇÃO
Universidade de Trás-os-Montes e Alto-Douro (Vila Real, Portugal)
2009/09 Sustained P2X3 facilitation of acetylcoline release contribute to bladder hyperactivity in humans with benign prostatic hyperplasia. 6TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE.
INTERNATIONAL SOCIETY FOR AUTONOMIC NEUROSCIENCE (Sidney, Australia)
2009/07 Muscarinic M3-induced ADO and SP release from capsaicin-sensitive neurons facilitates ACh release in the myenteric plexus. THIRD JOINT ITALIAN - GERMAN PURINE CLUB MEETING
GERMAN PURINE CLUB MEETING (Camerino, Italy)
2009/03 Activation of P2X1 purinoceptors facilitate evoked acetylcholine release in human obstructed bladders 24TH CONGRESS OF THE EUROPEAN ASSOCIATION OF UROLOGY
EUROPEAN ASSOCIATION OF UROLOGY (Estocolmo, United Kingdom)
2009/02 Substance P and adenosine released from capsaicin-sensitive nerve fibres interact to facilitate Ach release from myenteric neurons through the activation of NK1 and A2A receptors IJUP09 - ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO
Universidade do Porto (Porto, Portugal)
2008/12 Neonatal Capsaicin-Treated rats exhibit low extracelular purine levels at the myenteric plexus: Functional Implications XXXIX REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA
SOCIEDADE PORTUGUESA DE FARMACOLOGIA (Lisboa, Portugal)
2008/11 Importância das Taquicininas na neuromodelação purinérgica no plexo mioentérico de íleo de rato 2as JORNADAS DE BIOLOGIA: BIODIVERSIDADE /BIOADVERSIDADE
Universidade de Trás-os-Montes e Alto-Douro (Vila Real, Portugal)
2008/06 Tachykinergic control of acetylcholine release from myenteric neurons requires high levels of endogenous adenosine activating A2A receptors. CONGRESSO INTERNACIONAL PURINES 2008.
PURINES SOCIETY (Copenhaga, Denmark)
2008/02 Synergism between adenosine A2A and tachykinin NK1 receptors facilitate [3H]-ACh release from myenteric neurons. IJUP08 - ENCONTRO DE JOVENS INVESTIGADORES DA U.PORTO
Universidade do Porto (Porto, Portugal)
2007/12 Tachykinin-Induced Facilitation Of [3H]-Ach Release From Enteric Motoneurons Requires Activation Of Adenosine A2A Receptors XXXVIII REUNIÃO DA SOCIEDADE PORTUGUESA DE FARMACOLOGIA.
SOCIEDADE PORTUGUESA DE FARMACOLOGIA (Coimbra, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/09/06 - Current Implicações médico-legais da Covid-19 na população portuguesa
Supervisor
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2018 ß3-Adrenoceptors indirectly modulate cholinergic neurotransmission at the urinary bladder: on the mechanisms involving the outflow of adenosine
Co-supervisor
Universidade do Porto Faculdade de Ciências, Portugal
2016/09 - 2017/11 Controlo diferencial da libertação de acetilcolina e ATP pelo plexo mioentérioco do cólon de rato
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2016/09 - 2017/07 Intracellular signalling pathways underlying ß3 adrenoceptor-mediated inhibition of voiding in anaesthetized rats
Co-supervisor
 Biologia (Degree)
Universidade de Aveiro Departamento de Biologia, Portugal
2015/09 - 2016/12 Efeito neuromodulador do adrenocetor ß3 na bexiga de ratazana: Papel da ecto-fosfodiesterase, da CD73 e do recetor A1 da adenosina
Co-supervisor
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2012/09 - 2013/07 O paracetamol mata? Hábitos de consumo na população Portuguesa?
Supervisor
 Ciências Médico-Legais (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017 - 2018 1ª Reunião de Jovens Farmacologistas Portugueses (2018/02/05 - 2018/02/07)
Congress (Member of the Organising Committee)
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - 2013 XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXI Reunião de Farmacologia Clínica e XII Reunião de Toxicologia (2013/02/06 - 2013/02/08)
Congress (Member of the Organising Committee)
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 - 2006 IV Encontro Nacional de Marcadores Moleculares (2006/11/23 - 2006/11/24)
Meeting (Member of the Organising Committee)
 Universidade de Trás-os-Montes e Alto Douro, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/01 - Current Fórum das Profissões
Round table
2022/04/27 - 2022/04/27 Fórum das profissões
Round table
 Fórum das Profissões
Colégio das Caldinhas / Instituto Nun'Alvres, Portugal
2020/01/15 - 2020/01/15 Fórum das Profissões
Round table
 Fórum das Profissões
Colégio das Caldinhas / Instituto Nun'Alvres, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2014/12/03 Tese de Mestrado em Medicina Legal
Supervisor
 Débora Bianca De Almeida Santos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Association member

Society Organization name Role
2015 - Current American Autonomic Society Membro
2015 - Current International Society of Neurochemistry
2015 - Current International Society of Neurochemistry
2015 - Current American Autonomic Society
2011 - Current Sociedade Portuguesa de Farmacologia
2011 - Current Sociedade Portuguesa de Farmacologia
2010 - Current Sociedade Portuguesa de Bioquímica
2010 - Current Sociedade Portuguesa de Bioquímica
2009 - Current Sociedade Portuguesa de Neurociências
2009 - Current Sociedade Portuguesa de Neurociências
2008 - 2014 Sociedade Portuguesa de Biotecnologia
2008 - 2014 Sociedade Portuguesa de Biotecnologia

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - Current Biologia Molecular e Celular (Licenciatura) Escola Superior de Saúde Norte da Cruz Vermelha Portuguesa, Portugal
2022 - Current Análises Clínicas (Licenciatura) Escola Superior de Saúde Norte da Cruz Vermelha Portuguesa, Portugal
2010/09 - Current Toxicologia Forense Mestrado em Medicina Legal (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010/09 - 2018/12 Neuroquímica/Neurobiologia Mestrado em Bioquímica (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2016 - 2017 Membro da Comissão de Avaliação Externa da Agência de Avaliação e Acreditação do Ensino Superior (A3ES), da área de Biologia
Evaluator
 A3ES - Agência de Avaliação e Acreditação do Ensino Superior, Portugal A3ES - Agência de Avaliação e Acreditação do Ensino Superior
2015 - 2016 Membro da Comissão de Autoavaliação do 3º Ciclo de Estudos em Ciências Biomédicas do Instituto de Ciências Biomédicas Abel Salazar - UP
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interview (tv / radio show)

Program Topic
2016/04 - 2016/04 Mentes que brilham - Porto Canal Novo tratamento para a doença da bexiga

Journal scientific committee

Journal title (ISSN) Publisher
2022/01/02 - Current Plos One
2022 - Current Frontiers in Pharmacology
2020/11/25 - Current Biochemical Pharmacology (0006-2952)
2013 - Current Food and Chemical Toxicology (0278-6915) Elsevier

Mentoring / Tutoring

Topic Student name
2019/11 - 2020/02 Introductory Course in Laboratory Animal Science Joana do Amaral Saavedra
Distinctions

Award

2017 2ND PRIZE TO BEST POSTER
Associação Portuguesa de Urologia, Portugal
2015 BEST POSTER PRESENTATION IN CLINICAL RESEARCH
Australian Neuroscience Society, Australia
2014 EPHAR POSTER AWARD
2011 BEST POSTER
Universidade de Trás-os-Montes e Alto Douro, Portugal

Other distinction

2017 FEBS BURSARY
Federation of European Biochemical Societies, Germany
2017 ADVANCED SCHOOL AWARD
International Society for Neurochemistry, Switzerland
2016 SPB SCHOLARYSHIP TO ATTEND THE XIX NATIONAL CONGRESS OF BIOCHEMISTRY
Sociedade Portuguesa de Bioquímica, Portugal
2016 TRAVEL AWARD FOR YOUNG SCIENTIST AT THE EPHAR CONGRESS
EPHAR, Switzerland
2015 ALBERTO MALLIANI TRAVEL GRANT AWARD
2015 ISN TRAVEL AWARD
International Society for Neurochemistry, Switzerland
2014 TRAVEL GRANT
2014 WCP2014 CONGRESS BURSARY
International Union of Basic and Clinical Pharmacology, United States
2013 FEBS BURSARY WINNER
Federation of European Biochemical Societies, Germany
2012 TRAVEL AWARD
Purines society, Germany
2010 APOIO FINANCEIRO – FTC (FACC)
Associação para a Inovação e Desenvolvimento da FCT, Portugal