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Valeria C Santos-Ebinuma has been working with the production of biomolecules from microorganisms since her Master's degree. In March 2013, she obtained the title of Doctor of Science from the University of São Paulo. Between March 2013 and June 2013 she did a technical internship at the Federal University of Bahia. However, in June 2013 she obtained approval for a postdoctoral scholarship from the University of São Paulo with funding from FAPESP, which she enjoyed until August 2013. Since August 2013, she has been working as an Assistant Professor in the Department of Engineering Bioprocesses and Biotechnology from FCFAr / UNESP, Brazil Since then, she has been exercising her professional career as an Assistant Professor, having already created a research group, BioPPuL - Bioproducts ’Production and Purification Laboratory. Currently, she has accreditation in the Postgraduation programs of -Biosciences and Biotechnology Applied to Pharmacy Program. Valéria C Santos-Ebinuma presents expertise in the development of the production process and scale up from incubator shaker to bioreactor. she also works with the extraction of biomolecules from the fermented broth. Her interest is the production of natural products such as colorants, enzymes, including biopharmaceuticals, from the production step, their characterization, until their purification process.
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Identification

Personal identification

Full name
Valeria de Carvalho Santos-Ebinuma Ebinuma

Citation names

  • Ebinuma, Valeria
  • Santos-Ebinuma, V.C.

Author identifiers

Ciência ID
D418-2C4F-FD56
ORCID iD
0000-0002-6666-6695

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Advanced (C1) Upper intermediate (B2) Advanced (C1) Upper intermediate (B2)
Education
Degree Classification
2009 - 2013
Concluded
 Science (Postgraduate Certificate)
Universidade de São Paulo, Brazil
2007 - 2009
Concluded
 Science (Master)
Universidade de São Paulo, Brazil
2003 - 2007
Concluded
 Biochemical Engineering (Graduado)
Universidade de São Paulo, Brazil
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2013/08/21 - Current Assistant Professor (University Teacher) Universidade Estadual Paulista Júlio de Mesquita Filho, Brazil
Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de Araraquara, Brazil
Projects

Grant

Designation Funders
2018 - Current Development of sustainable nanomaterials for the purification of antileukemic drugs
2018/06908-8
Principal investigator
Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de Araraquara, Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo
Ongoing
2022/09/01 - 2027/08/31 Biotechnological process for the development of natural colorants from microbial sources for industrial application: phase II
2021/06686-8
Co-Principal Investigator (Co-PI)
Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de Araraquara, Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo
Ongoing
2017/04 - 2024/03 EMU concedido no processo 14/01580-3: cromatógrafo contracorrente
16/23776-2
Principal investigator
Fundação de Amparo à Pesquisa do Estado de São Paulo
2018/04 - 2020/03 Sustainable citrus waste biorefining as a source of value added bioproducts
17/50303-0
Principal investigator
Fundação de Amparo à Pesquisa do Estado de São Paulo
2015/01 - 2018/12 Processo biotecnológico visando o desenvolvimento de novos colorantes naturais microbianos para aplicação industrial
14/01580-3
Principal investigator
Fundação de Amparo à Pesquisa do Estado de São Paulo

Other

Designation Funders
2020 - Current Development of ionic liquids-based electroconductive hydrogels
2019/15493-9
Principal investigator
Fundação de Amparo à Pesquisa do Estado de São Paulo
Ongoing
Outputs

Publications

Book chapter
  1. Almeida, Mafalda R.; Neves, Márcia C.; Morales-Torres, Sérgio; Freire, Mara G.; Faria, Joaquim L.; Santos-Ebinuma, Valéria C.; Silva, Cláudia G.; Tavares, Ana P. M.. "Biomedical-related applications of functionalized nanomaterials". Elsevier, 2020.
    10.1016/B978-0-12-816787-8.00009-0
Conference paper
  1. Almeida, Mafalda; Barros, M. Amélia; Freire, Mara G.; Santos-Ebinuma, Valéria C.; Silva, Cláudia G.; Tavares, Ana P. M.. "Development of sustainable nanomaterials for the purification of antileukemic drugs". 2019.
  2. Almeida, Mafalda R.; Nunes, João C. F.; Cristóvão, Raquel. O.; Barros, M. Amélia; Freire, Mara G.; Santos-Ebinuma, Valéria C.; Faria, Joaquim L.; Silva, Cláudia G.; Tavares, Ana P. M.. "Purification of antileukemic drugs using functionalized nanomaterials". 2019.
  3. Almeida, Mafalda R.; Nunes, João C. F.; Barros, M. Amélia; Freire, Mara G.; Santos-Ebinuma, Valéria C.; Faria, Joaquim L.; Silva, Cláudia G.; Tavares, Ana P. M.. "Carbon nanomaterials for the purification of antileukemic drugs". 2019.
  4. Gomes, G.V.P.; Assis, D.J.; Da Silva, J.B.A.; Santos-Ebinuma, V.C.; Costa, L.A.S.; Druzianl, J.I.. "Obtaining Xanthan Gum Impregnated with Cellulose Microfibrils Derived from Sugarcane Bagasse". 2015.
    10.1016/j.matpr.2015.04.042
Journal article
  1. Cassamo U. Mussagy; Jorge F. B. Pereira; Valéria C. Santos-Ebinuma; Adalberto Pessoa, Jr; Vijaya Raghavan. "Insights into using green and unconventional technologies to recover natural astaxanthin from microbial biomass". Critical Reviews in Food Science and Nutrition (2023): https://doi.org/10.1080/10408398.2022.2093326.
    10.1080/10408398.2022.2093326
  2. Pedro Garcia Pereira Silva; Cassamo U. Mussagy; Caio de Azevedo Lima; Valéria C. Santos-Ebinuma; Janaína Fernandes de Medeiros Burkert; Lucielen Oliveira Santos. "Sustainable approach to recover ß-carotene and astaxanthin from Phaffia rhodozyma grown in a stirred-tank bioreactor under the influence of magnetic fields". Bioresource Technology (2023): https://doi.org/10.1016/j.biortech.2023.129906.
    10.1016/j.biortech.2023.129906
  3. Cassamo U. Mussagy; Fabiane O. Farias; Josana C. Sasaki; Mateus Scontri; Flavio Picheli; Valéria C. Santos-Ebinuma; Henriette M.C. de Azeredo; Adalberto Pessoa, Jr.; Rondinelli D. Herculano. "Eutectic solvent-based bioactive films functionalized with microbial astaxanthin extends shelf life of fresh strawberries". Materials Today Chemistry (2023): https://doi.org/10.1016/j.mtchem.2023.101721.
    10.1016/j.mtchem.2023.101721
  4. Caio A. Lima; Heitor B.S. Bento; Flávio P. Picheli; Fernando R. Paz-Cedeno; Cassamo U. Mussagy; Fernando Masarin; Mario A. Torres Acosta; Valéria C. Santos-Ebinuma. "Process development and techno-economic analysis of co-production of colorants and enzymes valuing agro-industrial citrus waste". Sustainable Chemistry and Pharmacy (2023): https://doi.org/10.1016/j.scp.2023.101204.
    10.1016/j.scp.2023.101204
  5. Cecília Naomi Nakamura; Nathalia Vieira Porphirio Veríssimo; Fernanda Oliveira; Clarissa P. Frizzo; Germán Pérez-Sánchez; João A.P. Coutinho; Jorge F.B. Pereira; Valéria C. Santos-Ebinuma. "Extraction of natural colorants using supramolecular solvents composed of Triton X-114 and ionic liquids". Separation and Purification Technology (2023): https://doi.org/10.1016/j.seppur.2023.124070.
    10.1016/j.seppur.2023.124070
  6. Cassamo U. Mussagy; Jorge F. B. Pereira; Laurent Dufossé; Vijaya Raghavan; Valeria C. Santos-Ebinuma; Adalberto Pessoa, Jr.. "Advances and trends in biotechnological production of natural astaxanthin by Phaffia rhodozyma yeast". Critical Reviews in Food Science and Nutrition (2023): https://doi.org/10.1080/10408398.2021.1968788.
    10.1080/10408398.2021.1968788
  7. Cassamo U. Mussagy; Maria Gonzalez-Miquel; Valeria C. Santos-Ebinuma; Jorge F. B. Pereira. "Microbial torularhodin – a comprehensive review". Critical Reviews in Biotechnology (2023): https://doi.org/10.1080/07388551.2022.2041540.
    10.1080/07388551.2022.2041540
  8. Fernanda de Oliveira; Santiago Zapata-Boada; S. S. da Silva; Rosa M. Cuéllar-Franca; Valéria C. Santos-Ebinuma. "Improving the Environmental Sustainability of Polyketides Colorants Production by Talaromyces Strain through Better Hydrodynamic Design in Bioreactors". ACS Sustainable Chemistry & Engineering (2022): https://doi.org/10.1021/acssuschemeng.2c02960.
    10.1021/acssuschemeng.2c02960
  9. Mariza Aires-Fernandes; Ramon Botelho Costa; Stéphanie Rochetti do Amaral; Cassamo Ussemane Mussagy; Valéria C. Santos-Ebinuma; Fernando Lucas Primo. "Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment—From Benchtop to Clinical Practice". Molecules (2022): https://doi.org/10.3390/molecules27206848.
    10.3390/molecules27206848
  10. Heitor B. S. Bento; Gabriela B. Paiva; Mafalda R. Almeida; Claúdia G. Silva; Pedro J. Carvalho; Ana P. M. Tavares; Danielle B. Pedrolli; Valéria C. Santos-Ebinuma. "Aliivibrio fischeri L-Asparaginase production by engineered Bacillus subtilis: a potential new biopharmaceutical". Bioprocess and Biosystems Engineering (2022): https://doi.org/10.1007/s00449-022-02769-x.
    10.1007/s00449-022-02769-x
  11. Raquel O. Cristóvão; Rita A. M. Barros; João G. Pinho; Lília S. Teixeira; Márcia C. Neves; Mara G. Freire; Joaquim L. Faria; et al. "Unveiling the Influence of Carbon Nanotube Diameter and Surface Modification on the Anchorage of L-Asparaginase". Applied Sciences (2022): https://doi.org/10.3390/app12178924.
    10.3390/app12178924
  12. Giórgia S. Barbieri; Heitor B. S. Bento; Fernanda de Oliveira; Flávio P. Picheli; Lídia M. Dias; Fernando Masarin; Valéria C. Santos-Ebinuma. "Xylanase Production by Talaromyces amestolkiae Valuing Agroindustrial Byproducts". BioTech 11 2 (2022): 15-15. https://doi.org/10.3390/biotech11020015.
    10.3390/biotech11020015
  13. Rita A. M. Barros; Raquel O. Cristóvão; Márcia C. Neves; Mara G. Freire; Joaquim Luís Faria; Valeria Santos-Ebinuma; Ana Paula Mora Tavares; Cláudia Gomes Silva. "Immobilization and Characterization of L-Asparaginase over Carbon Xerogels". BioTech (2022): https://www.mdpi.com/2673-6284/11/2/10.
    10.3390/biotech11020010
  14. João C. F. Nunes; Mafalda R. Almeida; Rui M. F. Bento; Matheus M. Pereira; Valéria C. Santos-Ebinuma; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "Enhanced Enzyme Reuse through the Bioconjugation of L-Asparaginase and Silica-Based Supported Ionic Liquid-like Phase Materials". Molecules 27 3 (2022): 929-929. https://doi.org/10.3390/molecules27030929.
    10.3390/molecules27030929
  15. Daniela Remonatto; Bárbara Ribeiro Ferrari; Juliana Cristina Bassan; Cassamo Ussemane Mussagy; Valéria de Carvalho Santos-Ebinuma; Ariela Veloso de Paula. "Utilization of Clay Materials as Support for Aspergillus japonicus Lipase: An Eco-Friendly Approach". Catalysts (2021): https://doi.org/10.3390/catal11101173.
    10.3390/catal11101173
  16. João C. F. Nunes; Raquel O. Cristóvão; Valéria C. Santos-Ebinuma; Joaquim L. Faria; Cláudia G. Silva; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "L-Asparaginase-Based Biosensors". Encyclopedia (2021): https://doi.org/10.3390/encyclopedia1030065.
    10.3390/encyclopedia1030065
  17. Daniel Castro; Ana Sofia C. Marques; Mafalda R. Almeida; Gabriela B. de Paiva; Heitor B. S. Bento; Danielle B. Pedrolli; Mara G. Freire; Ana P. M. Tavares; Valéria C. Santos-Ebinuma. "L-asparaginase production review: bioprocess design and biochemical characteristics". Applied Microbiology and Biotechnology 105 11 (2021): 4515-4534. https://doi.org/10.1007/s00253-021-11359-y.
    10.1007/s00253-021-11359-y
  18. Soares, Bruna P.; Santos, João H.P.M.; Martins, Margarida; Almeida, Mafalda R.; Santos, Nathalia V.; Freire, Mara G.; Santos-Ebinuma, Valéria C.; et al. "Purification of green fluorescent protein using fast centrifugal partition chromatography". Separation and Purification Technology 257 (2021): 117648. http://dx.doi.org/10.1016/j.seppur.2020.117648.
    10.1016/j.seppur.2020.117648
  19. de Oliveira, Fernanda; Hirai, Patrícia Rie; Teixeira, Maria Francisca Simas; Pereira, Jorge F.B.; Santos-Ebinuma, Valéria C.. "Talaromyces amestolkiae cell disruption and colorant extraction using imidazolium-based ionic liquids". Separation and Purification Technology 257 (2021): 117759. http://dx.doi.org/10.1016/j.seppur.2020.117759.
    Accepted • 10.1016/j.seppur.2020.117759
  20. Mussagy, Cassamo Ussemane; Guimarães, Ana Alice Carizia; Rocha, Lara Vicente Ferreira; Winterburn, James; Santos-Ebinuma, Valéria de Carvalho; Pereira, Jorge Fernando Brandão. "Improvement of carotenoids production from Rhodotorula glutinis CCT-2186". Biochemical Engineering Journal 165 (2021): 107827. http://dx.doi.org/10.1016/j.bej.2020.107827.
    Published • 10.1016/j.bej.2020.107827
  21. Mariana Vendrasco Tacin; Tales A. Costa-Silva; Ariela Veloso de Paula; Jose M. Palomo; Valéria de Carvalho Santos-Ebinuma. "Microbial lipase: a new approach for a heterogeneous biocatalyst". Preparative Biochemistry & Biotechnology (2020): 1-12. https://doi.org/10.1080/10826068.2020.1855442.
    10.1080/10826068.2020.1855442
  22. Nunes, João C. F.; Cristóvão, Raquel O.; Freire, Mara G.; Santos-Ebinuma, Valéria C.; Faria, Joaquim L.; Silva, Cláudia G.; Tavares, Ana P. M.. "Recent Strategies and Applications for l-Asparaginase Confinement". Molecules 25 24 (2020): 5827. http://dx.doi.org/10.3390/molecules25245827.
    Published • 10.3390/molecules25245827
  23. Fernanda de Oliveira; Caio de Azevedo Lima; André Moreni Lopes; Daniela de Araújo Viana Marques; Janice Izabel Druzian; Adalberto Pessoa Júnior; Valéria Carvalho Santos-Ebinuma. "Microbial Colorants Production in Stirred-Tank Bioreactor and Their Incorporation in an Alternative Food Packaging Biomaterial". Journal of Fungi 6 4 (2020): 264-264. https://doi.org/10.3390/jof6040264.
    10.3390/jof6040264
  24. Fernanda de Oliveira; Laura Carmona Ferreira; Álvaro Baptista Neto; Maria Francisca Simas Teixeira; Valéria de Carvalho Santos Ebinuma. "Biosynthesis of natural colorant by Talaromyces amestolkiae: Mycelium accumulation and colorant formation in incubator shaker and in bioreactor". Biochemical Engineering Journal 161 (2020): 107694-107694. https://doi.org/10.1016/j.bej.2020.107694.
    10.1016/j.bej.2020.107694
  25. Cruz Filho, Raimundo Felipe da; dos Santos, Januário Gama; Palheta, Rosana Antunes; Santos-Ebinuma, Valéria Carvalho; Viana Marques, Daniela de Araújo; Teixeira, Maria Francisca Simas. "Comparison of conventional and extractive fermentation using aqueous two-phase system to extract fibrinolytic proteases produced by Bacillus stearothermophilus DPUA 1729". Preparative Biochemistry & Biotechnology 51 2 (2020): 191-200. http://dx.doi.org/10.1080/10826068.2020.1805756.
    10.1080/10826068.2020.1805756
  26. Raquel O. Cristóvão; Mafalda R. Almeida; Maria A. Barros; João C. F. Nunes; Rui A. R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. "Development and characterization of a novel l-asparaginase/MWCNT nanobioconjugate". RSC Advances (2020): https://doi.org/10.1039/D0RA05534D.
    10.1039/D0RA05534D
  27. Mussagy, Cassamo U.; Santos-Ebinuma, Valéria C.; Kurnia, Kiki A.; Dias, Ana C. R. V.; Carvalho, Pedro; Coutinho, João A. P.; Pereira, Jorge F. B.. "Integrative platform for the selective recovery of intracellular carotenoids and lipids from Rhodotorula glutinis CCT-2186 yeast using mixtures of bio-based solvents". Green Chemistry 22 23 (2020): 8478-8494. http://dx.doi.org/10.1039/d0gc02992k.
    Published • 10.1039/d0gc02992k
  28. Ebinuma, Valeria. "Protic Ionic Liquids as Cell-Disrupting Agents for the Recovery of Intracellular Carotenoids from Yeast Rhodotorula glutinis CCT-2186". ACS Sustainable Chemistry & Engineering (2019): http://dx.doi.org/10.1021/acssuschemeng.9b04247.
    10.1021/acssuschemeng.9b04247
  29. Paloma A. M. Nascimento; Flávio P. Picheli; André M. Lopes; Jorge F. B. Pereira; Valéria C. Santos-Ebinuma. "Effects of cholinium-based ionic liquids on Aspergillus niger lipase: Stabilizers or inhibitors". Biotechnology Progress 35 5 (2019): https://doi.org/10.1002/btpr.2838.
    10.1002/btpr.2838
  30. Fernanda de Oliveira; Danielle Biscaro Pedrolli; Maria Francisca Simas Teixeira; Valéria de Carvalho Santos-Ebinuma. "Water-soluble fluorescent red colorant production by Talaromyces amestolkiae". Applied Microbiology and Biotechnology 103 16 (2019): 6529-6541. https://doi.org/10.1007/s00253-019-09972-z.
    10.1007/s00253-019-09972-z
  31. Camila Lopes; Nathalia Vieira dos Santos; Jana Dupont; Danielle Biscaro Pedrolli; Sandro Roberto Valentini; Valéria Santos-Ebinuma; Jorge Fernando Brandão Pereira. "Improving the cost effectiveness of enhanced green fluorescent protein production using recombinant Escherichia coli BL21 (DE3): Decreasing the expression inducer concentration". Biotechnology and Applied Biochemistry 66 4 (2019): 527-536. https://doi.org/10.1002/bab.1749.
    10.1002/bab.1749
  32. Ebinuma, Valeria. "Production and extraction of carotenoids produced by microorganisms". Applied Microbiology and Biotechnology (2019): http://dx.doi.org/10.1007/s00253-018-9557-5.
    10.1007/s00253-018-9557-5
  33. Ebinuma, Valeria; Tacin, Mariana Vendrasco [UNESP]; Massi, Fernanda Pelisson; Fungaro, Maria Helena Pelegrinelli; Teixeira, Maria Francisca Simas; de Paula, Ariela Veloso [UNESP]; de Carvalho Santos-Ebinuma, Valéria [UNESP]. "Biotechnological valorization of oils from agro-industrial wastes to produce lipase using Aspergillus sp. from Amazon". Biocatalysis and Agricultural Biotechnology (2019): http://dx.doi.org/10.1016/j.bcab.2018.11.013.
    10.1016/j.bcab.2018.11.013
  34. Ebinuma, Valeria. "Effect of electrolytes as adjuvants in GFP and LPS partitioning on aqueous two-phase systems: 2. Nonionic micellar systems". Separation and Purification Technology 210 (2019): 69-79. http://www.sciencedirect.com/science/article/pii/S1383586618318872.
    https://doi.org/10.1016/j.seppur.2018.07.078
  35. Nascimento, Paloma Andrade Martins [UNESP]; Pereira, Jorge Fernando Brandão [UNESP]; de Carvalho Santos-Ebinuma, Valéria [UNESP]; Paloma Andrade Martins Nascimento; Jorge Fernando Brandão Pereira; Valéria de Carvalho Santos-Ebinuma. "Insights into the effect of imidazolium-based ionic liquids on chemical structure and hydrolytic activity of microbial lipase". Bioprocess and Biosystems Engineering 42 7 (2019): 1235-1246. http://hdl.handle.net/11449/187582.
    http://dx.doi.org/10.1007/s00449-019-02121-w
  36. Ebinuma, Valeria. "Production of ß-Lactamase Inhibitors by Streptomyces Species". Antibiotics (2018): http://www.mdpi.com/2079-6382/7/3/61.
    10.3390/antibiotics7030061
  37. Ebinuma, Valeria. "Aqueous Biphasic Systems Composed of Cholinium Chloride and Polymers as Effective Platforms for the Purification of Recombinant Green Fluorescent Protein". ACS Sustainable Chemistry & Engineering 6 7 (2018): 9383-9393. https://doi.org/10.1021/acssuschemeng.8b01730.
    10.1021/acssuschemeng.8b01730
  38. Ebinuma, Valeria; Torres, Fábio Aurélio Esteves [UNESP]; de Almeida Francisco, Ana Clara [UNESP]; Pereira, Jorge Fernando Brandão [UNESP]; Santos-Ebinuma, Valéria de Carvalho [UNESP]. "Imidazolium-based ionic liquids as co-surfactants in aqueous micellar two-phase systems composed of nonionic surfactants and their aptitude for recovery of natural colorants from fermented broth". Separation and Purification Technology 196 (2018): 262-269. http://www.sciencedirect.com/science/article/pii/S1383586617307761.
    https://doi.org/10.1016/j.seppur.2017.07.056
  39. Sabo, Sabrina da Silva; Lopes, André Moreni [UNESP]; Santos-Ebinuma, Valéria de Carvalho [UNESP]; Rangel-Yagui, Carlota de Oliveira; Oliveira, Ricardo Pinheiro de Souza; Ebinuma, Valeria. "Bacteriocin partitioning from a clarified fermentation broth of Lactobacillus plantarum ST16Pa in aqueous two-phase systems with sodium sulfate and choline-based salts as additives". Process Biochemistry 66 (2018): 212-221. http://hdl.handle.net/11449/170442.
    http://dx.doi.org/10.1016/j.procbio.2017.11.018
  40. Lopes, André Moreni [UNESP]; Molino, João Vitor Dutra; dos Santos-Ebinuma, Valéria Carvalho [UNESP]; Pessoa, Adalberto; Valentini, Sandro Roberto [UNESP]; Pereira, Jorge Fernando Brandão [UNESP]. "Effect of electrolytes as adjuvants in GFP and LPS partitioning on aqueous two-phase systems: 1. Polymer-polymer systems". (2018): http://hdl.handle.net/11449/179907.
    http://dx.doi.org/10.1016/j.seppur.2018.04.090
  41. Panas, P.; Lopes, C.; Cerri, M.O.; Ventura, S.P.M.; Santos-Ebinuma, V.C.; Pereira, J.F.B.. "Purification of clavulanic acid produced by Streptomyces clavuligerus via submerged fermentation using polyethylene glycol/cholinium chloride aqueous two-phase systems". Fluid Phase Equilibria 450 (2017): 42-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025628778&partnerID=MN8TOARS.
    10.1016/j.fluid.2017.07.005
  42. de Lencastre Novaes, L.C.; Jozala, A.F.; Lopes, A.M.; de Carvalho Santos-Ebinuma, V.; Mazzola, P.G.; Pessoa Junior, A.. "Stability, purification, and applications of bromelain: A review". Biotechnology Progress 32 1 (2016): 5-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947346866&partnerID=MN8TOARS.
    10.1002/btpr.2190
  43. Santos-Ebinuma, V.C.; Teixeira, M.F.S.; Pessoa, A.; Jauregi, P.. "Separation of natural colorants from the fermented broth of filamentous fungi using colloidal gas aphrons". Separation and Purification Technology 163 (2016): 100-108. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959225726&partnerID=MN8TOARS.
    10.1016/j.seppur.2016.02.037
  44. Torres, F.A.E.; Zaccarim, B.R.; de Lencastre Novaes, L.C.; Jozala, A.F.; Santos, C.A.; Teixeira, M.F.S.; Santos-Ebinuma, V.C.. "Natural colorants from filamentous fungi". Applied Microbiology and Biotechnology 100 6 (2016): 2511-2521. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961286250&partnerID=MN8TOARS.
    10.1007/s00253-015-7274-x
  45. Viana Marques, D.A.; Santos-Ebinuma, V.C.; Pessoa-Júnior, A.; Porto, A.L.F.; Torres, B.R.; Converti, A.. "Effect of aeration and agitation on extractive fermentation of clavulanic acid by using aqueous two-phase system". Biotechnology Progress 32 6 (2016): 1444-1452. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994632215&partnerID=MN8TOARS.
    10.1002/btpr.2333
  46. Jozala, A.F.; de Lencastre-Novaes, L.C.; Lopes, A.M.; de Carvalho Santos-Ebinuma, V.; Mazzola, P.G.; Pessoa-Jr, A.; Grotto, D.; Gerenutti, M.; Chaud, M.V.. "Bacterial nanocellulose production and application: a 10-year overview". Applied Microbiology and Biotechnology 100 5 (2016): 2063-2072. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958897554&partnerID=MN8TOARS.
    10.1007/s00253-015-7243-4
  47. Santos-Ebinuma, V.C.; Lopes, A.M.; Pessoa, A.; Teixeira, M.F.S.. "Extraction of natural red colorants from the fermented broth of Penicillium purpurogenum using aqueous two-phase polymer systems". Biotechnology Progress 31 5 (2015): 1295-1304. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945461221&partnerID=MN8TOARS.
    10.1002/btpr.2127
  48. Silva, M.D.S.C.; Santos-Ebinuma, V.D.C.; Lopes, A.M.; Rangel-Yagui, C.D.O.. "Dextran sulfate/Triton X two-phase micellar systems as an alternative first purification step for clavulanic acid". Fluid Phase Equilibria 399 (2015): 80-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929463333&partnerID=MN8TOARS.
    10.1016/j.fluid.2015.04.026
  49. André Moreni Lopes; Valéria de Carvalho Santos-Ebinuma; Alexsandra Conceição Apolinário; Francisco Jaime Bezerra Mendonça; Bolívar Ponciano Goulart de Lima Damasceno; Adalberto Pessoa; José Alexsandro da Silva. "5CN05 partitioning in an aqueous two-phase system: A new approach to the solubilization of hydrophobic drugs". Process Biochemistry 49 9 (2014): 1555-1561. http://dx.doi.org/10.1016/j.procbio.2014.05.017.
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  50. Valéria Carvalho Santos-Ebinuma; Inês Conceição Roberto; Maria Francisca Simas Teixeira; Adalberto Pessoa Jr.. "Improvement of submerged culture conditions to produce colorants by Penicillium purpurogenum". Braz. J. Microbiol. 45 2 (2014): 731-742. http://dx.doi.org/10.1590/s1517-83822014000200049.
    10.1590/s1517-83822014000200049
  51. Daniela A. Viana Marques; Valéria de Carvalho Santos-Ebinuma; Patrícia Maria Sobral de Oliveira; Gláucia Manoella de Souza Lima; Janete M. Araújo; José L. Lima-Filho; Attilio Converti; Adalberto Pessoa-Júnior; Ana L.F. Porto. "Screening of wild type Streptomyces isolates able to overproduce clavulanic acid". Braz. J. Microbiol. 45 3 (2014): 919-928. http://dx.doi.org/10.1590/s1517-83822014000300022.
    10.1590/s1517-83822014000300022
  52. A. M. Lopes; V. C. Santos-Ebinuma; A. Pessoa Júnior; C. O. Rangel-Yagui. "Influence of salts on the coexistence curve and protein partitioning in nonionic aqueous two-phase micellar systems". Braz. J. Chem. Eng. 31 4 (2014): 1057-1064. http://dx.doi.org/10.1590/0104-6632.20140314s00002677.
    10.1590/0104-6632.20140314s00002677
  53. Jozala, A.F.; Pértile, R.A.N.; dos Santos, C.A.; de Carvalho Santos-Ebinuma, V.; Seckler, M.M.; Gama, F.M.; Pessoa, A.; et al. "Bacterial cellulose production by Gluconacetobacter xylinus by employing alternative culture media". Applied Microbiology and Biotechnology 99 3 (2014): 1181-1190. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925500659&partnerID=MN8TOARS.
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  54. Molino, João Vitor Dutra; Feitosa, Valker A.; Novaes, Leticia Celia de Lencastre; Ebinuma, Valéria de Carvalho Santos [UNESP]; Lopes, André Moreni; Jozala, Angela Faustino; Marques, Daniela de Araujo Viana; Malpiedi, L. Pellegrine; Pessoa Júnior, Adalberto. "Biomolecules extracted by ATPs: practical examples". (2014): http://hdl.handle.net/11449/133638.
  55. Dutra-Molino, J.V.; Araujo Feitosa, V.; de Lencastre-Novaes, L.C.; de Carvalho Santos-Ebinuma, V.; Moreni Lopes, A.; Faustino Jozala, A.; de Aráujo Viana Marques, D.; Pellegrini Malpiedi, L.; Pessoa Jr., A.. "Biomolecules extracted by ATPS: Practical examples | Biomoléculas extraídas por sbas: Ejemplos prácticos". Revista Mexicana de Ingeniera Qumica 13 2 (2014): 359-377. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904277615&partnerID=MN8TOARS.
  56. Letícia Celia de Lencastre Novaes; Valéria de Carvalho Santos Ebinuma; Priscila Gava Mazzola; Adalberto Pessoa Júnior. "Polymer-based alternative method to extract bromelain from pineapple peel waste". Biotechnology and Applied Biochemistry 60 5 (2013): 527-535. http://dx.doi.org/10.1002/bab.1121.
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  57. Valeria Carvalho Santos-Ebinuma. "Submerged Culture Conditions for the Production of Alternative Natural Colorants by a New Isolated Penicillium purpurogenum DPUA 1275". J. Microbiol. Biotechnol. 23 6 (2013): 802-810. http://dx.doi.org/10.4014/jmb.1211.11057.
    10.4014/jmb.1211.11057
  58. André Moreni Lopes; Valéria de Carvalho Santos-Ebinuma; Leticia Celia de Lencastre Novaes; João Vitor Dutra Molino; Leandro Ramos Souza Barbosa; Adalberto Pessoa; Carlota de Oliveira Rangel-Yagui. "LPS–protein aggregation influences protein partitioning in aqueous two-phase micellar systems". Appl Microbiol Biotechnol 97 14 (2013): 6201-6209. http://dx.doi.org/10.1007/s00253-013-4922-x.
    10.1007/s00253-013-4922-x
  59. Valéria Carvalho Santos-Ebinuma; Inês Conceição Roberto; Maria Francisca Simas Teixeira; Adalberto Pessoa. "Improving of red colorants production by a new Penicillium purpurogenum strain in submerged culture and the effect of different parameters in their stability". Biotechnol Progress 29 3 (2013): 778-785. http://dx.doi.org/10.1002/btpr.1720.
    10.1002/btpr.1720
  60. Jorge F.B. Pereira; Filipa Vicente; Valéria C. Santos-Ebinuma; Janete M. Araújo; Adalberto Pessoa; Mara G. Freire; João A.P. Coutinho. "Extraction of tetracycline from fermentation broth using aqueous two-phase systems composed of polyethylene glycol and cholinium-based salts". Process Biochemistry 48 4 (2013): 716-722. http://dx.doi.org/10.1016/j.procbio.2013.02.025.
    10.1016/j.procbio.2013.02.025
  61. Raquel Brandão Haga; Valéria Carvalho Santos-Ebinuma; Marcela de Siqueira Cardoso Silva; Adalberto Pessoa; Carlota O. Rangel-Yagui. "Clavulanic acid partitioning in charged aqueous two-phase micellar systems". Separation and Purification Technology 103 (2013): 273-278. http://dx.doi.org/10.1016/j.seppur.2012.10.034.
    10.1016/j.seppur.2012.10.034
  62. Larissa de Souza Kirsch; Valeria de Carvalho Santos Ebinuma; Maria Francisca Simas Teixeira. "Mycelial Biomass and Biochemical Properties of Proteases Produced by Lentinus citrinus DPUA 1535 (Higher Basidiomycetes) in Submerged Cultivation". Int J Med Mushr 15 5 (2013): 505-515. http://dx.doi.org/10.1615/intjmedmushr.v15.i5.80.
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  63. Valéria Carvalho Santos-Ebinuma; André Moreni Lopes; Attilio Converti; Adalberto Pessoa; Carlota de Oliveira Rangel-Yagui. "Behavior of Triton X-114 cloud point in the presence of inorganic electrolytes". Fluid Phase Equilibria 360 (2013): 435-438. http://dx.doi.org/10.1016/j.fluid.2013.09.053.
    10.1016/j.fluid.2013.09.053
  64. Ventura, Sonia P. M.; Santos-Ebinuma, Valeria C.; Pereira, Jorge F. B.; Teixeira, Maria F. S.; Pessoa, Adalberto; Coutinho, Joao A. P.; Sónia P. M. Ventura; et al. "Isolation of natural red colorants from fermented broth using ionic liquid-based aqueous two-phase systems". J Ind Microbiol Biotechnol 40 5 (2013): 507-516. http://hdl.handle.net/10773/19890.
    10.1007/s10295-013-1237-y
  65. Valéria Carvalho Santos; Francislene Andréia Hasmann; Attilio Converti; Adalberto Pessoa. "Liquid–liquid extraction by mixed micellar systems: A new approach for clavulanic acid recovery from fermented broth". Biochemical Engineering Journal 56 1-2 (2011): 75-83. http://dx.doi.org/10.1016/j.bej.2011.05.011.
    10.1016/j.bej.2011.05.011