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Mariana Biscaia Caleiras. Completed the Mestrado in Biotecnologia Farmacêutica in 2019/09/27 by Universidade de Coimbra Faculdade de Farmácia and Licenciatura in Bioquímica in 2017/06/13 by Universidade de Coimbra Faculdade de Ciencias e Tecnologia.
Identification

Personal identification

Full name
Mariana Biscaia Caleiras

Citation names

  • Biscaia-Caleiras, Mariana

Author identifiers

Ciência ID
D615-1015-B896

Websites

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2020/04/15 - 2025/01/31
Ongoing
 Mariana Biscaia Caleiras (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Bluepharma, Portugal
"TOWARDS THE SCALABLE MANUFACTURING OF LIPID-BASED COMPLEX INJECTABLES - A Quality-By-Design Approach " (THESIS/DISSERTATION)
2017/08/19 - 2019/09/27
Concluded
 Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Targeted delivery of doxorubicin and C6-ceramide combinations to non-small cell lung cancer cells -Key factors for C6-ceramide cytotoxicity" (THESIS/DISSERTATION)
 18
2017/09/18 - 2018/05/30
Concluded
 Curso de Formação de Inglês do Quotidiano, nível Avançado II (C1) (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
 17
2014/09/11 - 2017/06/13
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 16
2017/01 - 2017/06
Concluded
 Academic module: "Entreperneurship and Business Project" (Outros)
Universidade de Coimbra Faculdade de Economia, Portugal
Affiliation

Others

Category
Host institution 		Employer
2024/06/13 - Current Formulation Scientist Bluepharma, Portugal
Outputs

Publications

Book chapter
  1. Abreu, Teresa; Biscaia, Mariana (D615-1015-B896); Gonçalves, Nélio; Fonseca, Nuno A.; Moreira, João Nuno. ""In vitro and in vivo tumor models for the evaluation of anticancer nanoparticles"". In Biomedicine for Cancer Therapy, edited by Hélder Santos; Flavia Fontana. Springer Nature, 2020.
    In press
Conference abstract
  1. Bensa, Veronica; Biscaia-Caleiras, Mariana; Ponzoni, Mirco; Moreira, João Nuno; Brignola, Chiara; Fabio Pastorino. "Abstract 3204: Antitumor activity of a coencapsulated liposomal formulation of ceramides and doxorubicin in neuroblastoma model". Paper presented in AACR, San Diego, 2024.
Conference poster
  1. Biscaia-Caleiras, Mariana; Fonseca, Nuno A.; Lourenco, Ana Sofia; Nunes, Antonio; Moreira, João Nuno; Simões, Sérgio. "Addressing the challenges of industrial manufacturing of lipid-based complex injectables: fine-tuning of membrane fluidity using quality-by-design as a tool to enhance process effectiveness". Paper presented in AAPS-PharmSci360, 2023.
  2. Biscaia, Mariana (D615-1015-B896); Fonseca, Nuno A.; Cruz, Ana; Gonçalves, Nélio; Moreira, João Nuno. ""Targeted delivery of doxorubicin and C6-ceramide combinations to non-small cell lung cancer cells - Key factors for C6-ceramide's cytotoxocity"". Paper presented in 1st Annual Meeting in Pharmaceutical Sciences, 2019.
Journal article
  1. Biscaia-Caleiras, Mariana; Fonseca, Nuno A.; Lourenco, Ana Sofia; Moreira, João Nuno; Simões, Sérgio. "Rational formulation and industrial manufacturing of lipid-based complex injectables: Landmarks and trends". Journal of Controlled Release (2024):
  2. A.F. Cruz; Biscaia-Caleiras, Mariana; Fonseca, Nuno A.; Gonçalves, Nelio; V.M. Mendes; S.F. Sampaio; V.Moura; et al. "The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway, Cancers". Cancers (2021):
    Published
Thesis / Dissertation
  1. Biscaia, Mariana. ""Targeted delivery of doxorubicin and C6-ceramide combinations to non-small cell lung cancer cells - Key factors for C6-ceramide's cytotoxocity"". Master, Universidade de Coimbra Faculdade de Farmácia, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/06 Bridging the fine-tuning of lipid membrane fluidity with the industrial challenges of complex injectables manufacturing Liposome Research Days 2024
(Glasgow, United Kingdom)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/10/04 - 2019/10/04 Workshop - “How to Get Published” by Anthony Newman, Elsevier
Workshop
 Workshop - “How to Get Published”
2018/04/19 - 2018/04/20 "World Health Summit - Regional Meeting Coimbra"
Meeting
 "World Health Summit - Regional Meeting Coimbra"
2017/06/18 - 2017/06/24 "FEBS Advanced Lecture Course on Oncometabolism - From Conceptual Knowledge to Clinical Applications" - 6-day course which provided the participants with a comprehensive overview of established and emerging topics in the fast growing field of oncometabolism. The scientific programme covered a wide range of topics, from basic concepts, to recent breakthroughs, advanced techniques and clinical applications. "FEBS Advanced Lecture Course on Oncometabolism - From Conceptual Knowledge to Clinical Applications"
Federation of European Biochemical Societies, United Kingdom
2017/03 - 2017/03 "Bioempreende o teu futuro - 5ª edição" - regional academic entrepreneurship competition, which provided me the opportunity to receive expert mentoring and develop interpersonal skills such as creative thinking, problem solving and communicating skills. "Bioempreende o teu futuro - 5ª edição"
2016/01 - 2016/10 "5º Concurso Universitário CAP - Cultiva o teu futuro" - National entrepreneurship competition on the moto of innovation in the milk and dairy sector. 5º Concurso Universitário CAP - Cultiva o teu futuro
2016/05 - 2016/05 "Bioempreende o teu futuro - 4ª edição" - regional academic entrepreneurship competition, which provided me the opportunity to receive expert mentoring and develop interpersonal skills such as creative thinking, problem solving and communicating skills. "Bioempreende o teu futuro - 4ª edição"
2016 - 2016 "Arrisca C"- Entrepreneurship Contest which aimed to stimulate the development of business concepts around which the creation of new companies could be expected. Arrisca C
Universidade de Coimbra, Portugal
2015 - 2015 "Creative C" - Entrepreneurship Contest in which students from the Inov C region could develop and demonstrate their entrepreneurial skills through 5 challenges on the topics: Originality, Marketing and Communication, Problem Solving, Social4aDay and Business Intelligence. Creative C
Universidade de Coimbra, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/01/05 - 2023/01/05 Scale-up of nanoformulations: design and risk management (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
Distinctions

Award

2023 Best Abstract Award (AAPS-PharmSci360, 2023)
American Association of Pharmaceutical Scientists, United States
2015 Mention of honor - SOCIAL4ADAY (Creative C)
Universidade de Coimbra, Portugal