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Identification

Personal identification

Full name
Rodrigo Trinca Paulino

Citation names

  • Paulino, Rodrigo

Author identifiers

Ciência ID
D816-ED6E-1632

Email addresses

  • paulinot.rodrigo@gmail.com (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Upper intermediate (B2) Proficiency (C2)
German Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Spanish; Castilian Elementary (A2) Elementary (A2) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2023/10 - 2027/09
Ongoing
Biomedical Science (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal

Aquracy Therapeutics, Portugal
2022/10/01 - 2023/09/30
Concluded
Experimental Approaches in Biomedicine (Especialização pós-bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2019/09/15 - 2022/07/11
Concluded
Biotechnology (Licenciatura)
Major in Bachelor
Universidade do Algarve - Campus de Gambelas, Portugal
15
Affiliation

Science

Category
Host institution
Employer
2022/10/03 - 2023/09/30 Research Assistant (Research) Universidade do Algarve Centro Académico de Investigação e Formação Biomédica do Algarve, Portugal
Projects

Grant

Designation Funders
2023/10 - Current Advancing the development of a gene therapy for Cockayne Syndrome Type B
2023.02477.BDANA
PhD Student Fellow
2022/10/03 - 2023/09/30 Investigação de terapias experimentais em estudos pré-clínicos para o Síndroma de Cockayne
431#ABC-RI
Scientific Initiation Fellow
Universidade do Algarve Centro Académico de Investigação e Formação Biomédica do Algarve, Portugal
Concluded
Outputs

Publications

Conference paper
  1. Afonso, Inês T.; Koppenol, Rebekah; Conceição, André; Paulino, Rodrigo; Mirapalheta, Lourenzo; Matos, Carlos A; Nóbrega, Clévio. "From the molecular hallmarks to motor behavior: characterization of a new transgenic mouse model for spinocerebellar ataxia type 2". 2023.
Conference poster
  1. Paulino, Rodrigo; Afonso-Reis, Ricardo; Costa, Rafael G; Filipa Costa; Cristiana Madeira; Nóbrega, Clévio David Rodrigues . Corresponding author: Nóbrega, Clévio David Rodrigues. "Evaluation of DNA damage on neuronal cells through single cell gel electrophoresis". Paper presented in Ciência 2023, 2023.
  2. Paulino, Rodrigo; Afonso-Reis, Ricardo; Costa, Rafael G; Couto Filipa; Nóbrega, Clévio David Rodrigues . Corresponding author: Nóbrega, Clévio David Rodrigues. "Development and optimization of a comet assay to evaluate DNA damage in neuronal cells.". Paper presented in Fens Regional Meeting Conference, 2023.
  3. Paulino, Rodrigo; Afonso-Reis, Ricardo; Costa, Rafael G; Couto Filipa; Madeira Cristiana; Nóbrega, Clévio David Rodrigues . Corresponding author: Nóbrega, Clévio David Rodrigues. "Comet assay: optimization and evaluation of DNA damage in neuronal cells.". Paper presented in European Neuroscience Conference by Doctoral Students, 2023.
  4. Madeira Cristiana; Afonso-Reis, Ricardo; Paulino, Rodrigo; Nóbrega, Clévio David Rodrigues ; Sofia M. Calado; Matos, Carlos A. "Neuronal cultures differentiated from patient-derived induced pluripotent stem cells as a novel model of Cockayne syndrome B.". Paper presented in European Neuroscience Conference by Doctoral Students, 2023.
  5. Couto Filipa; Codêsso José; Paulino, Rodrigo; Nóbrega, Clévio David Rodrigues. "Overexpression of the RNA binding protein HSPA8 in Spinocerebellar Ataxia type 2". Paper presented in European Neuroscience Conference by Doctoral Students., 2023.
  6. Couto Filipa; Codêsso, José Miguel; Paulino, Rodrigo; Nóbrega, Clévio David Rodrigues. "Modulation of the RNA binding protein HSPA8 in Spinocerebellar Ataxia type 2". Paper presented in Fens Regional Meeting Conference, 2023.
  7. Afonso, Inês T.; Koppenol, Rebekah; Conceição, André; Vieira R; Paulino, Rodrigo; Mirapelha, L.; Matos, Carlos A; Nóbrega, Clévio David Rodrigues . Corresponding author: Nóbrega, Clévio David Rodrigues. "From the molecular hallmarks to motor behavior: characterization of a novel transgenic mouse model for Spinocerebellar ataxia type 2". Paper presented in ISN-ESN, 2023.
  8. Madeira, Cristiana R; Afonso-Reis, Ricardo; Paulino, Rodrigo; Nóbrega, Clévio David Rodrigues ; Matos, Carlos A; Sofia M. Calado. "Generation of a novel Cockayne syndrome B neuronal culture model from patient-derived induced pluripotent stem cells". Paper presented in FENS Regional Meeting 2023 (FRM 2023), 2023.
  9. Paulino, Rodrigo; Afonso-Reis, Ricardo; Cristiana R. Madeira; Nóbrega, Clévio David Rodrigues. "Evaluation of DNA damage on neuronal cells through single cell gel electrophorasis". Paper presented in Ciência, 2023.
  10. Conceição, André; Koppenol, Rebekah; Inês Afonso; Paulino, Rodrigo; Mirapalheta, Lourenzo; Matos, Carlos; Nóbrega, Clévio David Rodrigues. "A novel SCA2 transgenic mouse model displays disease-associated phenotype.". Paper presented in FENS Regional Meeting 2023 ¿ Algarve, 2023.
Journal article
  1. Paulino, Rodrigo; Nóbrega, Clévio David Rodrigues . Corresponding author: Nóbrega, Clévio David Rodrigues. "Autophagy in spinocerebellar ataxia type 3: from pathogenesis to therapeutics". International Journal of Molecular Sciences (2023):
    Accepted
Thesis / Dissertation
  1. "Preliminary studies for the characterization of a new transgenic animal model for Spinocerebellar Ataxia type 2". Degree, Universidade do Algarve, 2022.

Intellectual property

Patent
  1. Paulino, Rodrigo; Nóbrega, Clévio David Rodrigues. 2023. "Compounds and composition for DNA protection".
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/07 Unlocking Therapeutic Potential: Early-Stage Pharmacological Screening to Alleviate DNA Damage Sociedade Portuguesa de Farmacologia
NOVA medical school (Lisbon, Portugal)
2023 Characterization of a new transgenic mouse model for spinocerebellar ataxia type 2 with 129 glutamine repeats: unraveling neuropathologic and motor phenotype. FloripaNeuro
(Florianópolis, Brazil)
2022 Spinocerebellar ataxia type 2: characterization of a novel transgenic mouse model with neuropathological and motor phenotype. Portuguese Association of Movement Disorders
(Lisbon, Portugal)

Event participation

Activity description
Type of event
Event name
Institution / Organization
2023/05 - Current Volunteer work at Fens Regional Meeting Conference organization

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/10 - 2024/11 ESN-ISN Neurochemistry School, Comet Assay: a robust tool to evaluate DNA damage in neurons. (Curso de doutoramento (conclusão de unidades curriculares))

Mentoring / Tutoring

Topic Student name
2024/01/01 - 2024/07/01 Analyzing expression profile of a gene based therapy on mice brain for Cockayne Syndrome type B Emilia Salgueiro
2024/01/01 - 2024/07/01 Avaliação do padrão de biodistribuição do vetor viral AAV em zonas cerebrais em um modelo animal. Daniel Ashitani
2024/03/01 - 2024/04/07 Identificação de terapias farmacológicas para o tratamento da Síndrome de Cockayne Tipo B Francisco João Rita Miguel
2024/03/01 - 2024/04/07 ESTUDO DA DISTRIBUIÇÃO DE AAV’S (ADENO ASSOCIATED VIRUSES) EM MURGANHOS Anderson Pereira Araujo
2023/08 - 2024/02 Avaliação da adequação de medicamentos para o tratamento da Síndrome de Cockayne tipo B Diana Noias
2023/07 - 2023/08 Evaluation of CSB expression with pharmacological induction in, in vitro model Catarina Anastácio
2023/02/01 - 2023/07/01 Evaluation of DNA damage induction with hydrogen peroxide through the single-cell gel electrophoresis technique. Nathalia Elizabeth Alvear Crespo
2023/06 - 2023/07 Optimization of pharmacological screening protocol for a in vitro model Miguel Marques
2022/05 - 2023/06 Pharmacological screening of a drug library as a possible treatment for Cockayne Syndrome in cellular model. Anderson Pereira Araujo
2022/08/01 - 2023/01/30 Investigation of pharmacological therapy in a cellular model of Cockayne Syndrome Anderson Araujo
Distinctions

Award

2023 FCT PhD Scholarship - 2023.02477.BDANA
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Other distinction

2023 FRM23 Organization Travel Grants funded by IBRO
International Brain Research Organization, France