Identification
Personal identification
- Full name
- Diana Duarte Lobo
Citation names
- Lobo, Diana Duarte
Author identifiers
- Ciência ID
- D91F-7184-F767
- ORCID iD
- 0000-0001-5785-4283
Knowledge fields
- Medical and Health Sciences - Basic Medicine - Neurosciences
- Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Upper intermediate (B2) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Education
Degree | Classification | |
---|---|---|
2021/01/01 - 2025/01/01
Ongoing
|
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
"Overcoming the major roadblocks for successful AAV-based gene therapy in CNS" (THESIS/DISSERTATION)
|
|
2019/11/04 - 2019/11/15
Concluded
|
III Modular Structure Training in Laboratory Animal Science (Outros)
Coimbra Institute for Clinical and Biomedical Research, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
17,1 |
2015/09 - 2017/11
Concluded
|
Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Cerebrovascular and Blood-brain Barrier Impairments in Machado-Joseph Disease" (THESIS/DISSERTATION)
|
18 |
2012/09 - 2015/07
Concluded
|
Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
|
15 |
Affiliation
Others
Category Host institution |
Employer | |
---|---|---|
2021/01/01 - Current | PhD student at Gene and Stem Cell Therapies for the brain, CNC | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2022/04 - 2022/06 | Research Trainee at CNS Gene Therapy group, Lund University | Lunds Universitet, Sweden |
2018/05/11 - 2020/12/31 | Research Fellow at Gene and Stem Cell Therapies for the brain, CNC | Universidade de Coimbra, Portugal |
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal | ||
2015/02 - 2015/07 | Trainee | Centro de Sangue e daTransplantação de Coimbra – Áreas Funcionais do Sangue e da Transplantação, Portugal |
Centro de Sangue e daTransplantação de Coimbra – Áreas Funcionais do Sangue e da Transplantação, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2021/01/01 - Current | Accelerating Research & Development for Advanced Therapies (ARDAT)
PhD Student Fellow
Innovative Health Initiative, Belgium
|
European Union European Federation of Pharmaceutical Industries and Associations Ongoing
|
2020/11/01 - Current | Accelerating research & development for advanced therapies
Innovative Health Initiative, Belgium
|
European Commission European Federation of Pharmaceutical Industries and Associations Ongoing
|
2018/05/11 - Current | BrainHealth 2020: Deteção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias
SAICT 000008 BrainHealth 2020
Research Fellow
CNC.IBILI, Portugal
|
Ongoing
|
2021/01/01 - 2024/12/31 | Overcoming the major roadblocks for successful AAV-based gene therapy in the CNS
2020.09668.BD
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2020/06 - 2020/08 | Validação expedita e Fabrico em larga escala de um dispositivo de sopro para colheita com inativação de amostras para deteção
do SARS-CoV-2
269_596884125
Researcher
Universidade de Coimbra, Portugal
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal ViraVector - Unidade de produção vectores virais para transferência de genes, Portugal |
Fundação para a Ciência e a Tecnologia Agency for Clinical Research and Biomedical Innovation (AICIB) Ongoing
|
2016/04/01 - 2019/12/31 | Gene repair and repression strategies to alleviate Machado-Joseph disease
PTDC/NEU-NMC/0084/2014
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2018/09 - Current | Targeting mutant ATXN3 for the treatment of Spinocerebellar Ataxia 3 (SCA3)
CSD3#IV0020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Wave Life Sciences USA, Inc., United States |
Wave Life Sciences USA, Inc.
Ongoing
|
2023/09/01 - 2026/08/31 | NEURODIET - Molecular Mechanisms of Dietary Intervention on Neurodegeneration (PT001)
JPND/0001/2022
Universidade de Coimbra, Portugal
Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2023/03/01 - 2024/08/31 | Direct Conversion of Astrocytes into Cerebellar Neurons as an Innovative Treatment for Spinocerebellar Ataxia Type-3
2022.06127.PTDC
Universidade de Coimbra, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2019/12 - 2020/01 | A Therapeutic Strategy in Machado-Joseph Disease
CPD0020A01
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Blade Therapeutics
Ongoing
|
2019/02/20 - 2019/09/30 | Targeting ATXN3 for the treatment of Spinocerebellar Ataxia 3 (SCA3) using AAV5 and an artificial microRNA
NA
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
uniQure NV
Concluded
|
Other
Designation | Funders | |
---|---|---|
2020/03 - Current | Laboratório de Análises Clínicas da Universidade de Coimbra - SARS-Cov2 Detection
LAC-UC
Other
Universidade de Coimbra, Portugal
|
Ongoing
|
Outputs
Publications
Conference paper |
|
Conference poster |
|
Journal article |
|
Newspaper article |
|
Thesis / Dissertation |
|
Artistic / Performance
Theatre play |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2019/11/15 | Blood-brain barrier dysfunction as a neuropathological feature in Machado-Joseph Disease | 1st Annual Meeting in Pharmaceutical Sciences
Faculty of Pharmacy - University of Coimbra (Coimbra, Portugal)
|
2019/11/15 | Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain disorders | 1st Annual Meeting in Pharmaceutical Sciences
Faculty of Pharmacy - University of Coimbra (Coimbra, Portugal)
|
2019/06/01 | Blood-brain barrier dysfunction as a neuropathological feature in Machado-Joseph Disease: results from human and MJD mouse samples | XVI Meeting of the Portuguese Society for Neuroscience
Portuguese Society for Neuroscience (Lisbon, Portugal)
|
2019/02/06 | Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain diseases | XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia clínica, XVIII Reunião de toxicologia
Sociedade Portuguesa de Farmacologia, Farmacologia clínica e Toxicologia (Porto, Portugal)
|
2019/02 | Disruption of Blood-Brain Barrier in Machado-Joseph Disease | XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia clínica, XVIII Reunião de toxicologia
Sociedade Portuguesa de Farmacologia, Farmacologia clínica e Toxicologia (Porto, Portugal)
|
2018/02 | Cerebrovascular and Blood-Brain Barrier Impairments in Machado-Joseph Disease | XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia clínica, XVII Reunião de toxicologia
Sociedade Portuguesa de Farmacologia, Farmacologia clínica e Toxicologia (Lisboa, Portugal)
|
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2019/03 - Current | Brain Awareness Week initiative involves visits to schools to discuss neuroscience and to open the door of laboratories with
the aim of disseminating science among children.
Other
|
Science Communication - Brain Awareness Week 2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
2022/04/27 - 2022/04/29 | 2022- ESGCT SPRING SCHOOL ATHENS
Workshop
|
2022- ESGCT SPRING SCHOOL ATHENS
European Society of Gene and Cell Therapy, United Kingdom
|
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2023/09 - 2024/09 | CRISPR-based gene activation for the study and treatment of neurodegenerative disorders | Marcos Pinto |
Distinctions
Award
2019 | Scholarship to participate in the 2019 meeting of the Portuguese Society for Neuroscience
Portuguese Society for Neuroscience, Portugal
|