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EN Luis Antunes completed the MBA Masters of Business Management at the Institute of Business Management (Porto); the Diploma of Specialized Veterinary Studies in laboratory animal sciences in 2015 by the National School of Veterinary Medicine at the University of Toulouse (Le Mirail), title of Aggregate in 2014 from the University of Trás-os-Montes and Alto Douro, doctorate from the Faculty of Medicine in 2001 from the University of Newcastle, Master's Degree in 1996 from the Faculty of Medicine from the University of Coimbra, Degree in Veterinary Medicine in 1992 from the Faculty of Veterinary Medicine of Technical University of Lisbon. He is Associate Professor at the University of Trás-os-Montes and Alto Douro and Researcher at the Center for Research and Agro-Environmental and Biological Technologies at the University of Trás-os-Montes and Alto Douro and Researcher at the Institute of Molecular and Cellular Biology / Institute Research and Innovation in Health at the University of Porto. Responsible for the vivarium of the University of Trás-os-Montes and Alto Douro since 2015. He published more than 120 articles in specialized magazines, 6 book chapters and 4 books. He supervised 7 doctoral theses and co-supervised 3. He supervised 14 master's dissertations and he co-supervised 4. He supervised 1 work concluding a bachelor's / bachelor's course and co-supervised 1. He received 5 awards. Participates and / or participated as an Investigator in 4 projects as a responsible Investigator in 7 projects as an investigator. He works in the areas of Veterinary Sciences, Medical Sciences and Health with an emphasis on Basic Sciences, Anesthesiology and Animal Welfare. In its Ciência Vitae curriculum, the most frequent terms in the context of scientific production are: Anesthetic depth; Monitoring; Anesthesia; Veterinary; EEG and Animal Welfare Indexes. PT Luis Antunes. Concluiu o MBA Masters of Business Management no Institute of Business Management do Porto, o Diploma de estudos veterinário especializado em ciências de animais de laboratório em 2015 pela Escola nacional de Medicina Veterinária da Universidade de Toulouse II (Le Mirail), título de Agregado em 2014 pela Universidade de Trás-os-Montes e Alto Douro, doutoramento pela faculdade de medicina em 2001 pela Universidade de Newcastle, Mestrado em Mestrado em 1996 pela Faculdade de Medicina pela Universidade de Coimbra, Licenciatura em Medicina Veterinária em 1992 pela Faculdade de Medicina Veterinária da Universidade Técnica de Lisboa. É Professor Associado na Universidade de Trás-os-Montes e Alto Douro e Investigador no Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas da Universidade de Trás-os-Montes e Alto Douro e Investigador no Instituto de Biologia Molecular e Celular /Instituto de Investigação e Inovação em Saúde da Universidade do Porto. Responsável pelo biotério da Universidade de Trás-os-Montes e Alto Douro. Publicou mais de 120 artigos em revistas especializadas. Possui 6 capítulo(s) de livros e 4 livro(s). Orientou 7 teses de doutoramento e coorientou 3. Orientou 14 dissertações de mestrado e coorientou 4. Orientou 1 trabalho de conclusão de curso de licenciatura/bacharelato e coorientou 1. Recebeu 5 prémios e/ou homenagens. Participa e/ou participou como Investigador em 4 projetos como Investigador responsável em 7 projetos como investigador. Atua nas áreas de Ciências Veterinárias, Ciências Médicas e da Saúde com ênfase em Ciências Básicas, Anestesiologia e Bem-Estar Animal. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica são: Profundidade anestésica; Monitorização; Anestesia; Veterinária; Índices de EEG e Bem-Estar Animal.
Identification

Personal identification

Full name
LUÍS MIGUEL JOAQUIM MARQUES ANTUNES

Citation names

  • Antunes, Luis Miguel Joaquim Marques

Author identifiers

Ciência ID
DA1A-814B-FBF3
ORCID iD
0000-0002-9757-6879

Knowledge fields

  • Agrarian Sciences - Veterinary Sciences
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Clinical Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
Italian Intermediate (B1) Advanced (C1) Beginner (A1) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2016
Concluded
Business Management (Curso de mestrado (conclusão do curso de especialização))
Institute of Business Management, Pakistan
"NA" (THESIS/DISSERTATION)
16
2015
Concluded
Diplôme d'études specialisées vétérinaires en Sciences de l'animais de laboratoire (Diplôme d´études supérieures)
Ecole nationale vétérinaire de Toulouse, France

Universite de Toulouse II (Le Mirail), France
"Diplôme d'études specialisées vétérinaires en Sciences de l'animais de laboratoire" (THESIS/DISSERTATION)
Diploma "DESV"
2014
Concluded
n/a (Título de Agregado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
Aprovado
2014
Concluded
Provas de agregação (Título de Agregado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Potential artefacts induced by anesthesia in rodent models" (THESIS/DISSERTATION)
Aprovado por unanimidade
2001
Concluded
Degree of Doctor of Philosophy (Doutoramento)
Major in Faculdade de Medicina
Newcastle University, United Kingdom
"The use of the electroencephalogram and auditory evoked potentials to assess the depth of anaesthesia and effects of anaesthetic agents in the laboratory rat (Rattus norvegicus)”." (THESIS/DISSERTATION)
PhD
1996
Concluded
Mestrado (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
Muito Bom
1991
Concluded
Licenciatura (Licenciatura)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
14
Affiliation

Science

Category
Host institution
Employer
2015/07/01 - Current Researcher (Research) Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2004 - Current Associate Professor (University Teacher) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2001/10/26 - 2004/11/01 Assistant Professor (University Teacher) Universidade de Trás-os-Montes e Alto Douro, Portugal
2001/06/26 - 2001/10/25 Invited Assistant Professor (University Teacher) Universidade de Trás-os-Montes e Alto Douro, Portugal
1997/01/09 - 2001/06/25 Assistant (University Teacher) Universidade de Trás-os-Montes e Alto Douro, Portugal
1993/01/05 - 1996/10 Trainee Assistant (University Teacher) Universidade de Trás-os-Montes e Alto Douro, Portugal

Others

Category
Host institution
Employer
2015 - Current Investigador Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - 2021 Diretor do biotério da Universidade Universidade de Trás-os-Montes e Alto Douro, Portugal
2008/08/01 - 2009/07/01 Sabatica Oxford Brookes University Faculty of Health and Life Sciences, United Kingdom
2007 - 2007 Investigador Centro de Ciência Animal e Veterinária, Portugal
2002 - 2007 Responsável pelo biotério do Departamento de Ciências Veterinárias Universidade de Trás-os-Montes e Alto Douro, Portugal
Projects

Grant

Designation Funders
2013/07 - 2015/06 Zebrafish (Danio rerio)anaesthesia and potential implications in research - reduction, replacement and refining techniques/procedures
PTDC/CVT-WEL/4672/2012
Researcher
Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Ongoing
2010/06 - 2013/12 Improvements in cerebral blood flow and body organ perfusion during anaesthesia
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2007/10 - 2011/09 Development of Novel Sensors for Adequate Anaesthesia Assessment
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2007/07 - 2010/12 IDeA - Integrated Design for Automation of Anaesthesia
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2005/07 - 2008/06 Refinements in laboratory animals anaesthesia, behavioural and physiological measures
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2005/03 - 2008/02 Automation in Anaesthesia: Monitoring, Modelling and Control
Researcher
Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designation Funders
2018/06/01 - 2022/02/28 VALORIZEBYPRODUCTS .: Eficácia pré-clínica do sulforafano ou do extrato total de Brássicas: uma estratégia para combater a obesidade e valorizar os subprodutos de Brássicas
PTDC/ASP-HOR/29152/2017
Researcher
Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/01 - 2021/12/31 Optimização da anestesia em peixe-zebra: implicações económicas, clínicas e de bem-estar animal
PTDC/CVT-CVT/29542/2017
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/06/13 - 2013/12/11 Melhoramentos na perfusão sanguínea cerebral e na perfusão dos órgãos corporais durante procedimentos anestésicos
PTDC/CVT/101999/2008
Instituto Politécnico de Viseu, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Fundação Ensino e Cultura Fernando Pessoa, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Effects of Ketamine anaesthesia in animal models used on research (PI at IBMC - 80 606 ¿)
PTDC/CVT/099022/2008
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/10/01 - 2011/09/30 Desenvolvimento de Novos Sensores para Avaliação do Nível de Anestesia
PTDC/EEA-ACR/75454/2006
Hospital Geral de Santo António SA, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal

Instituto de Engenharia Mecânica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/07/10 - 2010/12/31 IDeA - Projecto INtegrado para Automação em Anestesia
PTDC/EEA-ACR/69288/2006
Universidade do Porto Faculdade de Ciências, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Centro Hospitalar Universitário de Santo António, Portugal

Hospital Geral de Santo António SA, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/07/01 - 2008/06/30 Melhorias na anestesia de animais de laboratório, comportamento e medidas fisiológias
POCI/CVT/59056/2004
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/03/01 - 2008/02/29 Automação em Anestesia: Monitorização, Modelação e Controlo
POSC/EEA-SRI/57607/2004
Hospital Geral de Santo António SA, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2013/07 - 2015/06 IntelLab II
ADI33877
Principal investigator
Universidade de Trás-os-Montes e Alto Douro, Portugal
Ongoing
Outputs

Publications

Book
  1. Félix, L.; Antunes, L.; Campos, S.; Venâncio, C.; Coimbra, A.M.. Recreational Use of Ketamine and Its Interaction with NMDA Receptors. 2016.
  2. Ferreira DA; Antunes, Luis Miguel Joaquim Marques; Amorim, P.; Nunes CS. Recent Advances in BIS Guided TCI Anesthesia. NY: Nova Publishers. 2010.
    Published
  3. Ferreira, D.A.; Nunes, C.; Antunes, L.; Amorim, P.. Propofol and remifentanil: Contributions to the improvement of target controlled infusion with BIS monitoring. 2010.
  4. Ribeiro, L.; Ferreira, D.A.; Amorim, P.; Lobo, F.; Nunes, C.; Antunes, L.. Hemodynamic and bispectral index responses to high doses of remifentanil in patients with brain tumors submitted to neurosurgical procedures. 2010.
Book chapter
  1. Félix, Luís; Antunes, Luís; Campos, Sónia; Venâncio, Carlos; Coimbra, Ana Maria. "Recreational Use of Ketamine and Its Interaction with NMDA Receptors". In Neuropathology of Drug Addictions and Substance Misuse, 672-680. Amesterdam: Elsevier, 2016.
    Published • 10.1016/B978-0-12-800212-4.00062-5
  2. Antunes, Luis Miguel Joaquim Marques; Silva A. "The use of the rabbit as an animal model for clinical electroencephalogram studies applied to depth of anaesthesia research: ethical considerations". In Large animals as biomedical models: Ethical, societal, legal and biological aspects, 150-160. Bad Neuenahr-Ahrweiler: Europaeische Akademie GmbH, 2012.
    Published
  3. Antunes, Luis Miguel Joaquim Marques. "Anestesia e Analgesia no Rato". In Microcirurgia (Técnica Cirúrgica e Patologia Experimental, 1-279. Lisboa, Portugal: Gulbenkian, 2011.
    Published
  4. Antunes, Luis Miguel Joaquim Marques. "Euthanasia". In The COST Manual of Laboratory Animal Care and Use: Refinement, Reduction, and Research, 355-368. Florida: CRC Press, 2010.
    Published
  5. Ferreira DA; Nunes, C. S.; Antunes, Luis Miguel Joaquim Marques; Amorim, P.. "Propofol and Remifentanil: Contributions to the Improvement of Target Controlled Infusion and BIS Monitoring". In Advances in Medicine and Biology, 57-92. New York: Nova Science Publishers, Inc., 2010.
    Published
  6. Ribeiro L; Ferreira DA; Amorim P; Lobo F; Nunes CS; Antunes, Luis Miguel Joaquim Marques. "General Anesthesia Research Developments". In Hemodynamic and Bispectral Index Responses to High Doses of Remifentanil in Patients with Brain Tumors Submitted to Neurosurgical Procedures, 119-128. New York: Nova Science Publishers, 2010.
    Published
Conference abstract
  1. Vidal, A.; Félix, L.; Antunes, L.; Coimbra, A.M.; Monteiro, Sandra Mariza. "Short term exposure to ketamine and its oxidative stress in zebrafish development.". Paper presented in 10th Iberian and 7th Iberoamerican Congress on Environmental Contamination and Toxicology, Vila Real, 2015.
    Published
  2. Félix, L.; Antunes, L.; Coimbra, Ana Maria. "Developmental impairment following chronic exposure to ketamine in early zebrafish (Danio rerio) embryos". Paper presented in 10th Iberian and 7th Iberoamerican Conference on Environmental Contamination and Toxicology, Vila Real, 2015.
    Published
  3. Félix, L.; Vidal, A.; Coimbra, Ana Maria; Antunes, L.. "Comparative analysis of teratogenic effects of ketamine and MS222 in zebrafish embryos". Paper presented in AAALAC International, ESLAV and ECLAM Conference 2015, Hannover, 2015.
    Published
  4. Serafim, C.; Félix, L.; Antunes, L.; Matos, M.; Coimbra, Ana Maria. "Real time PCR analysis of apoptotic genes expression in zebrafish embryos exposed to ketamine during early development". Paper presented in SEB Annual Meeting, Prague, 2015.
    Published
  5. Félix, L.; Antunes, L.; Coimbra, Ana Maria. "Exploring caspase-3 and 9 activity in ketamine-induced zebrafish embryos toxicity". Paper presented in SEB Annual Meeting, Prague, 2015.
    Published
  6. Serafim, C.; Félix, L.; Antunes, L.; Matos, M.; Coimbra, Ana Maria. "Real time PCR analysis of NMDA receptor expression in zebrafish embryos exposed to ketamine.". Paper presented in 10th Iberian and 7th Iberoamerican Conference on Environmental Contamination and Toxicology, Vila Real, 2015.
    Published
  7. Bras, Susana; Ribeiro, Lenio; Ferreira, David A.; Antunes, Luis; Nunes, Catarina S.. "Controlling the hypnotic drug (propofol) to maintain a stable depth of anesthesia, in dogs". Paper presented in 2014 IEEE International Symposium on Medical Measurements and Applications (MeMeA), Lisboa, Portugal, 2014.
    Published • 10.1109/MeMeA.2014.6860055
  8. Félix, L.; Antunes, L.; Coimbra, Ana Maria. "Developmental time course of ketamine induced toxicity in early zebrafish embryos". Paper presented in SEB Main Meeting, Manchester, 2014.
    Published
  9. Félix, L.; Coimbra, Ana Maria; Antunes, L.. "The zebrafish embryos as an alternative approach to anaesthetic animal research". Paper presented in 12th FELASA SECAL Congress, Barcelona, 2013.
    Published
  10. Félix, L.; Antunes, L.; Coimbra, Ana Maria. "Oxidative stress as biomarker of ketamine-induced toxicity during early zebrafish development". Paper presented in SEB Main Meeting, Valencia, 2013.
    Published
  11. Campos, S.; Félix, Luís; Venâncio, Carlos Alberto e Silva; Antunes, Luís; Peixoto, Francisco. "Decrease of state III mitochondrial respiration by prolonged infusion of propofol vehicle in rabbit liver.". Paper presented in Euroanaesthesia 2013 Congress, Barcelona, 2013.
    Published
  12. Valentim, A.M.; Magalhães, A.; Antunes, Luís; Venâncio, Carlos Alberto e Silva; Summavielle, Teresa; Pereira, M.. "Is ketamine alone and in combination with midazolam or dexmedetomidine safe regarding post-anaesthetic memory?". Paper presented in Euroanaesthesia 2013 Congress, Barcelona, 2013.
    Published
  13. Campos, S.; Lourdes Pinto, M.; Venâncio, Carlos Alberto e Silva; Guedes De Pinho, P.; Antunes, Luís. "Hepatic and Cardiac Effects of Long-Term Sedation with Propofol and Its Vehicle in Rabbits.". Paper presented in 12th FELASA SECAL Congress, Barcelona, 2013.
    Published
  14. Félix, L.; Antunes, L.; Coimbra, Ana Maria. "Ketamine acute toxicity assessment using the zebrafish (Danio rerio) embryo toxicity test". Paper presented in SEB Annual Meetin, Salzburg, 2012.
    Published
  15. Félix, L.; Coimbra, Ana Maria; Antunes, L.. "Zebrafish as early safety anaesthesiology screening assay". Paper presented in ASAB/SEB/NC3Rs Symposium-Implementing the 3Rs in behavioural and physiological research, London, 2012.
    Published
  16. Félix, L.; Antunes, L.; Coimbra, Ana Maria. "Estudo da toxicidade da cetamina no desenvolvimento do peixe-zebra". Paper presented in 6as Jornadas de Biologia na UTAD, Vila Real, 2012.
    Published
  17. Félix, L.; Coimbra, Ana Maria; Antunes, L.. "Early life-stage toxicity of ketamine in zebrafish (Danio rerio)". Paper presented in II SPCAL Meeting-Care for Laboratory Animals if you care for your research, Lisbon, 2012.
    Published
  18. Costa, B.A.; Figueiredo, R.; Lemos, J.M.; Silva, A.; Campos, S.; Antunes, Luis Miguel Joaquim Marques. "Assessment of the depth of anaesthesia in animals for automatic control". Paper presented in ECCE'10/ECCIE'10/ECME'10/ECC'10, Puerto de la Cruz, 2010.
    Published
  19. Oliveira, Ana Liza ; Ferreira, D.A.; Venâncio, Carlos Alberto ; Silva, Aura Maia ; Sousa, A.; Amorim, Pedro Pinho ; Antunes, Luís Marques ; Vala, Helena. "Morfometria Intestinal em Suínos". Paper presented in Encontro da Sociedade Portuguesa de Patologia Animal, Viseu, 2010.
    Published
  20. Silva, Aura Maia ; Ribeiro, Larissa Maciel ; Brás, Susana; Ferreira, D.A.; Antunes, Luís Marques. "CSI response to incision in dogs". Paper presented in Association of Veterinary Anaesthetists Autumn Meeting, Leipzig, 2008.
    Published
  21. Antunes, Luis Miguel Joaquim Marques. "Regular Bis Monitoring Results in Lighter Depth of Anaesthesia". Paper presented in 6Th International Symposium of Memory and Awareness in Anaesthesia and Intensive Care, Hull, 2004.
    Published
Conference paper
  1. Martins, Tânia; OLIVEIRA, PA.; Venâncio, C.; Eduardo Rosa; Antunes, Luis Miguel Joaquim Marques. "Effect of broccoli (Brassica oleracea var italica) flour byproducts in a murine model of obesity.". Paper presented in ESCI Annual Scientific Meeting - Virtual meeting, 2021.
    Published • https://doi.org/10.1111/eci.13564
  2. Susana Bras; Lenio Ribeiro; David A. Ferreira; Luis Antunes; Catarina S Nunes. "Controlling the hypnotic drug (propofol) to maintain a stable depth of anesthesia, in dogs". 2014.
    10.1109/memea.2014.6860055
  3. Ana Margarida Pereira; Luis Antunes; Ana Maria Valentim; Rui Correia; Joaquim Gabriel; Pereira, Ana Margarida; Antunes, Luis; et al. "Development of a respiratory rate monitoring device for mice anesthesia induction chamber". Paper presented in 2014 IEEE International Symposium on Medical Measurements and Applications (MeMeA), Lisboa, Portugal, 2014.
    Published • 10.1109/memea.2014.6860037
  4. Serafim, C.; Félix, L.; Antunes, L.; Matos, M.; Coimbra, Ana Maria. "Efeito da cetamina na expressão dos genes sonic hedgehog a e noggin 3 durante o desenvolvimento embrionário de peixe-zebra (Danio rerio)". Paper presented in 8as Jornadas de Biologia na UTAD, Vila Real, 2014.
    Published
  5. Vidal, A.; Félix, L.; Antunes, L.; Monteiro, Sandra Mariza; Coimbra, A.M.. "Monitoring of oxidative stress in zebrafish embryo development after ketamine exposure in different developmental phases.". Paper presented in SEB Annual Meeting, Mancheste, 2014.
    Published
  6. Félix, L.; Coimbra, A. M.; Antunes, L.. "Ketamine-induced developmental toxicity and apoptosis in zebrafish embryos: 9AP2-6". Paper presented in Euroanaesthesia 2013 Congress, Barcelona, 2013.
    Published
  7. Magalhães, A.; Valentim, A.M.; Pereira, P.; Melo, P.; Venâncio, Carlos Alberto e Silva; Antunes, Luís; Summavielle, Teresa. "Is Ketamine Alone or Combined with Midazolam or Dexmedetomidine a Good Anaesthetic to Use in Biomedical Research that Requires Behavioral Evaluation?". Paper presented in 12th FELASA SECAL Congress, Barcelona, 2013.
    Published
  8. Ribeiro PO; Silva, A.; Antunes, Luis Miguel Joaquim Marques; Gabriel, J.. "Temperature changes during ketamine anaesthesia in laboratory animals". Paper presented in EAT/2012, Porto, 2012.
    Published
  9. Campos, S.; Silva A; de Pinho PG; Antunes LM. "Blood Propofol Concentrations: On Demand for Pharmacokinetic/Pharmacodynamics Models and New Measurement Automatic Technologies". Paper presented in 1st International Workshop on Veterinary Biosignals and Biodevices, Vilamoura, Algarve, Portugal, 2012.
    Published • 10.5220/0003880900180023
  10. Silva A; Souza, A.P.; Venâncio, Carlos; Ferreira DA; Antunes LM. "Effect of Two Doses of Dexmedetomidine on Index of Consciousness and Permutation Entropy in Rabbits". Paper presented in 1st International Workshop on Veterinary Biosignals and Biodevices, Vilamoura, Algarve, Portugal, 2012.
    Published • 10.5220/0003879100430050
  11. Félix, L.; Coimbra, A. M.; Antunes, L.. "Ketamine can lead to malformation of zebrafish (Danio rerio) larvae: 9AP8-10". Paper presented in Euroanaesthesia 2012, Paris, 2012.
    Published
  12. Silva, A.; Souza, A.P.; Venâncio, C.; Ferreira, D.A.; Antunes, L.. "Effect of two doses of dexmedetomidine on index of consciousness and permutation entropy in rabbits". 2012.
  13. Antunes, L.; Gabriel, J.. "Foreword". 2012.
  14. Campos, S.; Silva, A.; De Pinho, P.G.; Antunes, L.. "Blood propofol concentrations: On demand for pharmacokinetic/ pharmacodynamics models and new measurement automatic technologies". 2012.
  15. Bras, S.; Ferreira, D. A.; Antunes, L.; Ribeiro, L.; Nunes, C. S.; Gouveia, S.; Brás, S.; Ferreira, D.A.; Nunes, C.S.. "EMG contributes to improve Cerebral State Index modeling in dogs anesthesia". Paper presented in 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Boston, MA, 2011.
    Published • 10.1109/IEMBS.2011.6091626
  16. Costa, B.A.; Figueiredo, R.; Lemos, J.M.; Silva, A.; Campos, S.; Antunes, L.. "Assessment of the Depth of Anaesthesia in animals for automatic control". 2010.
  17. Venâncio, Carlos Alberto ; Silva, Aura Maia ; Souza, Almir Pereira de ; Ferreira, D.A.; Antunes, Luís Marques. "Comparison of EEG Derived Anesthetic Depth Indexes in Rabbits under Fentanyl-Isoflurane Anesthesia". Paper presented in Annual Meeting of the American Society Anesthesiologists, New Orleans, 2009.
    Published
  18. Brás, Susana; Ribeiro, Lénio ; Ferreira, D.A.; Antunes, Luís Marques ; Amorim, Pedro Pinho ; Nunes, Catarina Sofia. "Cerebral state index (CSI) values could be strongly contaminated by high EMG levels in dogs". Paper presented in AVA Meeting, Barcelona, 2008.
    Published
  19. Bressan, Nadja; Castro, Ana; Bras, Susana; Oliveira, Helder P.; Ribeiro, Lenio; Ferreira, David A.; Antunes, Luis; Amorim, Pedro; Nunes, Catarina S.. "Synchronization Software for Automation in Anesthesia". Paper presented in 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Lyon, France, 2007.
    Published • 10.1109/IEMBS.2007.4353537
  20. Bressan, N.; Castro, A.; Bras, S.; Ribeiro, L.; Ferreira, D.A.; Silva, A.; Antunes, L.; Nunes, C.S.. "Modelling the dynamics of depth of anaesthesia: Cerebral state index in dogs". Paper presented in 2007 Mediterranean Conference on Control & Automation, Athens, Greece, 2007.
    Published • 10.1109/MED.2007.4433786
  21. Brás, Susana; Bressan, Nadja ; Ribeiro, Lénio ; Ferreira, D.A.; Antunes, Luís Marques. "Propofol Pharmacodynamic Effect On The Cerebral State Index In Dogs". Paper presented in First World Conference of Total Intravenous Anaesthesia, Venice, 2007.
    Published
  22. Castro, A.; Bressan, N.; Antunes, L.; Nunes, C.S.. "EEG entropy monitoring of depth of anaesthesia: Pharmacokinetic and dynamic modelling". 2007.
  23. Brás, S.; Bressan, N.; Ribeiro, L.; Ferreira, D.A.; Antunes, L.; Nunes, C.S.. "Nonlinear modeling of cerebral state index in dogs". 2007.
    10.1109/IEMBS.2007.4352346
  24. Nunes, Catarina Sofia ; Bressan, Nadja ; Ribeiro, Lénio ; Ferreira, D.A.; Antunes, Luís Marques. "Time to peak effect using the cerebral state index (CSI): determining the pharmacokinetics of propofol in dog". Paper presented in 9th World Congress of Veterinary Anaesthesia, Santos, 2006.
    Published
  25. Ferreira, D.A.; Ribeiro, Lénio ; Nunes, Catarina Sofia ; Bressan, Nadja ; Amorim, Pedro Pinho ; Alves, Héber ; Antunes, Luís Marques. "Brain monitoring with cerebral state index during induction of anaesthesia with propofol target controlled infusion in dogs". Paper presented in 9th World Congress of Veterinary Anaesthesia, Santos, 2006.
    Published
  26. Ribeiro, Lénio ; Ferreira, D.A.; Nunes, Catarina Sofia ; Bressan, Nadja ; Amorim, Pedro Pinho ; Alves, Héber ; Antunes, Luís Marques. "Target controlled infusion (TIVA): a useful and safe tool to anaesthetize dogs". Paper presented in 9th World Congress of Veterinary Anaesthesia, Santos, 2006.
    Published
  27. Antunes, Luís Marques ; Nunes, Catarina Sofia ; Ferreira, D.A.; Amorim, Pedro Pinho. "Do machines susbstitute clinical evaluation of anaesthetic depth? Closed-loop system: an automatic pilot in anaesthesia?". Paper presented in World Congress of Veterinary Anaesthesia, Santos, 2006.
    Published
  28. Nunes, C.S.; Mendonça, T.F.; Antunes, L.; Ferreira, D.A.; Lobo, F.; Amorim, P.. "Modelling drugs' pharmacodynamic interaction during general anaesthesia: The choice of pharmacokinetic model". 2006.
  29. Nunes, C.S.; Mendonca, T.F.; Amorim, P.; Ferreira, D.A.; Antunes, L.. "Comparison of Neural Networks, Fuzzy and Stochastic Prediction Models for return of consciousness after general anesthesia". Paper presented in 44th IEEE Conference on Decision and Control, Seville, Spain, 2005.
    Published • 10.1109/CDC.2005.1582925
  30. Ferreira, D.A.; Nunes, Catarina Sofia ; Antunes, Luís Marques ; Lobo, Francisco ; Santos, Isabel ; Casal, Manuela ; Amorim, Pedro Pinho. "The influence of brain tumours in BIS and in propofol predicted effect-site concentrations at loss of consciousness". Paper presented in Annual Scientific Meeting of the UK Society for Intravenous Anaesthesia, Edinburgh, 2005.
    Published
  31. Nunes, Catarina Sofia ; Ferreira, D.A.; Antunes, Luis; Amorim, Pedro Pinho ; Mendonça, Teresa. "Neuro-Fuzzy Modeling Techniques can predict return of consciousness after general anesthesia in surgical patients". Paper presented in Advanced Modeling and Control in Anesthesia - AMCA 2005, Monte Verità, 2005.
    Published
  32. Nunes, Catarina Sofia ; Ferreira, D.A.; Antunes, Luís Marques ; Amorim, Pedro Pinho ; Mendonça, Teresa. "Modeling Techniques can predict return of consciousness after general anesthesia in surgical patients". Paper presented in Advanced Modeling and Control in Anesthesia, Monte Verità, 2005.
    Published
  33. Nunes, Catarina Sofia ; Mendonça, Teresa ; Ferreira, D.A.; Antunes, Luís Marques ; Amorim, Pedro Pinho. "Propofol and remifentanil pharmacokinetics/pharmacodynamics are different during induction and maintenance of anesthesia". Paper presented in Advanced Modeling and Control in Anesthesia, Monte Verità, 2005.
    Published
  34. Ferreira, D.A.; Nunes, Catarina Sofia ; Lobo, Francisco ; Amorim, Pedro Pinho ; Antunes, Luís Marques. "Obesity and arterial hypertension do not influence the haemodynamic and BIS response to a large remifentanil bolus". Paper presented in Annual Scientific Meeting of the UK Society for Intravenous Anaesthesia, Edinburgh, 2005.
    Published
  35. Ferreira, D.A.; Nunes, Catarina Sofia ; Antunes, Luís Marques ; Amorim, Pedro Pinho. "The influence of brain tumours on BIS response to a remifentanil bolus". Paper presented in EURONEURO 2005, Cambridge, 2005.
    Published
  36. Nunes, C.; Ferreira, D.; Lobo, F.; Santos, I.A.; Antunes, Luis Miguel Joaquim Marques; Amorim, P.. "Influence of remifentanil in the prediction of propofol concentration at recovery of consciousness". Paper presented in Euroanaesthesia, Vienna, 2005.
    Published
  37. Nunes, C.S.; Mendonca, T.F.; Amorim, P.; Ferreira, D.A.; Antunes, L.M.. "Radial basis function neural networks versus fuzzy models to predict return of consciousness after general anesthesia". Paper presented in 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, San Francisco, CA, USA, 2004.
    Published • 10.1109/IEMBS.2004.1403295
  38. Antunes, Luís Marques ; Nunes, Catarina Sofia ; Ferreira, D.A.; Amorim, Pedro Pinho. "Variables related with the anaesthetic propofol predicted brain concentrations at return of consciousness in neurosurgical patients". Paper presented in 4TH Forum of European Neuroscience, Lisbon, 2004.
    Published
  39. Nunes, Catarina Sofia ; Ferreira, D.A.; Antunes, Luís Marques ; Santos, Isabel ; Casal, Manuela ; Nunes, Fernanda ; Ferreira, Leónia ; Amorim, Pedro Pinho. "Regular BIS monitoring results in lighter depth of anaesthesia". Paper presented in 6th International Symposium in Memory and Awareness in Anaesthesia and Intensive Care, Hull, 2004.
    Published
  40. Ferreira, D.A.; Nunes, Catarina Sofia ; Antunes, Luís Marques ; Amorim, Pedro Pinho. "Remifentanil has no direct effect on bispectral index of the electroencephalogram". Paper presented in 4TH Forum of European Neuroscience, Lisboa, 2004.
    Published
  41. Nunes, C.S.; Amorim, P.; Ferreira, D.A.; Antunes, Luís. "Modelling the effect of pharmacodynamic interactions on the bispectral index of the electroencephalogram (BIS) using Neuro-Fuzzy techniques". Paper presented in 4TH Forum of European Neuroscience, Lisbon, 2004.
    Published
  42. Nunes, Catarina Sofia ; Mendonça, Teresa ; Amorim, Pedro Pinho ; Ferreira, D.A.; Antunes, Luís Marques. "Stochastic and Neuro-Fuzzy Modelling for Predicting Return of Consciousness after General Anaesthesia". Paper presented in 3rd European Symposium on Intelligent Technologies, Hybrid Systems and Their Implementation on Smart Adaptive Systems, Aachen, 2004.
    Published
  43. Nunes, C.S.; Mendonça, T.F.; Amorim, P.; Ferreira, D.A.; Antunes, L.M.. "Radial basis function neural networks versus fuzzy models to predict return of consciousness after general anesthesia". 2004.
Conference poster
  1. Santos, C.; Valentim, Ana M; Félix, Luís; Antunes, Luis Miguel Joaquim Marques; Pinto, Maria de Lurdes. Corresponding author: Pinto, Maria de Lurdes. "Ketamine administration at the 1-4 somites stage zebrafish does not alter the distribution patterns of serotonin 5-ht-2b receptor in adult animals". Paper presented in Joint congress of Veterinary Pathology and Veterinary Clinical Pathology, 2023.
  2. Santos, C.A.; Félix, Luís Manuel Lourenço; Valentim, Ana M; Antunes, Luis Miguel Joaquim Marques; Pinto, Maria de Lurdes. Corresponding author: Pinto, Maria de Lurdes. "Effects of ketamine administration in the expression of Sox 2 in zebrafish CNS". Paper presented in Joint congress of Veterinary Pathology and Veterinary Clinical Pathology, 2023.
Journal article
  1. Tânia Martins; Tiago Ferreira; Bruno Colaço; Beatriz Medeiros-Fonseca; Maria de Lurdes Pinto; Ana Novo Barros; Carlos Venâncio; et al. "Absorption and Excretion of Glucosinolates and Isothiocyanates after Ingestion of Broccoli (Brassica oleracea L. var italica) Leaf Flour in Mice: A Preliminary Study". Nutraceuticals (2023): https://doi.org/10.3390/nutraceuticals3040039.
    10.3390/nutraceuticals3040039
  2. Tânia Martins; Ana Filipa Matos; Joana Soares; Rúben Leite; Maria João Pires; Maria de Lurdes Pinto; Neuparth, MJ; et al. "Effects of Sulforaphane and Chlorophyl a in a Western Diet-Induced Obesity Model". Obesities (2023): https://www.mdpi.com/2673-4168/3/4/22.
    10.3390/obesities3040022
  3. Tânia Martins; Ana Novo Barros; Eduardo Rosa; Luís Antunes. "Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review". Molecules (2023): https://doi.org/10.3390/molecules28145344.
    10.3390/molecules28145344
  4. José P. Castelão-Baptista; Sara A. Valente; Sara Canário; David Oppolzer; Ana Barros; Carlos Venâncio; Tânia Martins; et al. "Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity". Nutrients (2023): https://doi.org/10.3390/nu15040924.
    10.3390/nu15040924
  5. Tânia Martins; Tiago Ferreira; Elisabete Nascimento-Gonçalves; Catarina Castro-Ribeiro; Sílvia Lemos; Eduardo Rosa; Luís Miguel Antunes; Paula Alexandra Oliveira. "Obesity Rodent Models Applied to Research with Food Products and Natural Compounds". Obesities 2 2 (2022): 171-204. https://doi.org/10.3390/obesities2020015.
    10.3390/obesities2020015
  6. Tânia Martins; Catarina Castro-Ribeiro; Sílvia Lemos; Tiago Ferreira; Elisabete Nascimento-Gonçalves; Eduardo Rosa; Paula Alexandra Oliveira; Luís Miguel Antunes. "Murine Models of Obesity". Obesities (2022): https://doi.org/10.3390/obesities2020012.
    10.3390/obesities2020012
  7. Tânia Martins; Paula Oliveira; Maria João Pires; Maria João Neuparth; Germano Augusto Bacin Lanzarin; Luís Félix; Carlos Venâncio; et al. "Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study". Foods (2022): https://www.mdpi.com/2304-8158/11/1/120.
    10.3390/foods11010120
  8. TÂNIA MARTINS; RÚBEN LEITE; ANA FILIPA MATOS; JOANA SOARES; MARIA JOÃO PIRES; MARIA DE LURDES PINTO; MARIA JOÃO NEUPARTH; et al. "Beneficial Effects of Broccoli (Brassica oleraceavaritalica) By-products in Diet-induced Obese Mice". In Vivo (2022): http://dx.doi.org/10.21873/invivo.12943.
    10.21873/invivo.12943
  9. Luís Félix; Rita Correia; Rita Sequeira; Cristiana Ribeiro; Monteiro, S.M.; Luís Antunes; José António Silva; Carlos Venâncio; A M Valentim. "MS-222 and Propofol Sedation during and after the Simulated Transport of Nile tilapia (Oreochromis niloticus)". Biology (2021): http://dx.doi.org/10.3390/biology10121309.
    10.3390/biology10121309
  10. Rita Silva-Reis; Ana I. Faustino-Rocha; Mariana Gonçalves; Catarina Castro Ribeiro; Tiago Ferreira; Carla Ribeiro-Silva; Lio Gonçalves; et al. "Refinement of Animal Model of Colorectal Carcinogenesis through the Definition of Novel Humane Endpoints". Animals 11 4 (2021): 985-985. https://doi.org/10.3390/ani11040985.
    10.3390/ani11040985
  11. Félix, L.M.; Luzio, A.; Antunes, L.; Coimbra, A.M.; Valentim, A.M.. "Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222". Toxicology and Applied Pharmacology 412 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85099458113&partnerID=MN8TOARS.
    10.1016/j.taap.2020.115385
  12. Checchinato, Daniel; Antunes, Luis Miguel Joaquim Marques; Mendes, Joaquim; Hugo, Silva; Duarte, Diana; Antunes P. Coelho C. "Avaliação de um sistema de monitorização portátil do retorno anestésico baseado em análise de movimento em caninos e felinos (Evaluation of a portable anesthetic return monitoring system based on canine and feline movement analysis". Brazilian Journal of Development 6 8 (2020): 56064-56076. https://www.brazilianjournals.com/index.php/BRJD/article/view/14687.
    Open access • Published
  13. Félix, L.M.; Luzio, A.; Santos, A.; Antunes, L.M.; Coimbra, A.M.; Valentim, A.M.. "MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos". Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 237 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087124131&partnerID=MN8TOARS.
    10.1016/j.cbpc.2020.108834
  14. Luís Félix; Ana Maria Coimbra; Ana Maria Valentim; Luís Antunes. "Review on the use of zebrafish embryos to study the effects of anesthetics during early development". Critical Reviews in Toxicology (2019): 1-14. https://doi.org/10.1080/10408444.2019.1617236.
    10.1080/10408444.2019.1617236
  15. Leitaõ, C.J.; Lima-Rodríguez, J.R.; Ferreira, F.; Avelino, C.; Sánchez-Margallo, F.M.; Antunes, L.. "Parasympathetic Tone Activity Evaluation to Discriminate Ketorolac and Ketorolac/Tramadol Analgesia Level in Swine". Anesthesia and Analgesia 129 3 (2019): 882-889. http://www.scopus.com/inward/record.url?eid=2-s2.0-85071562740&partnerID=MN8TOARS.
    10.1213/ANE.0000000000003573
  16. Martins, Tânia; Colaço, Bruno; Venâncio, Carlos; Pires, Maria J; Oliveira, Paula A; Rosa, Eduardo; Antunes, Luís M.. "Potential effects of sulforaphane to fight obesity". Journal of the Science of Food and Agriculture 98 8 (2018): 2837-2844.
    Published • 10.1002/jsfa.8898
  17. Medeiros-Fonseca, B.; Mestre, V. F.; Colaço, B.; Pires, M. J.; Martins, T.; Gil da Costa, R. M.; Neuparth, M. J.; et al. "Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice". Food & Function 9 8 (2018): 4419-44.
    Published • 10.1039/c8fo00783g
  18. Félix, Luís M.; Vidal, Ana M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luís M.; Monteiro, Sandra M.; Matos, Manuela; Coimbra, Ana M.. "Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish ( Danio rerio ) embryos". Chemosphere 201 Marc 7 (2018): 730-739.
    Published • 10.1016/j.chemosphere.2018.03.049
  19. Martins, Tânia; Diniz, Enoque; Félix, Luís M.; Antunes, Luís; Shelden, Eric A.. "Evaluation of anaesthetic protocols for laboratory adult zebrafish (Danio rerio)". PLOS ONE 13 5 (2018): e0197846-e0.
    Published • 10.1371/journal.pone.0197846
  20. Félix, Luís M.; Luzio, Ana; Themudo, Maria; Antunes, Luís; Matos, Manuela; Coimbra, Ana M.; Valentim, Ana M.. "MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos". Reproductive Toxicology 81 Jul 24 (2018): 122-131.
    Published • 10.1016/j.reprotox.2018.07.086
  21. Martins, Tânia; Valentim, Ana M.; Pereira, Nuno; Antunes, Luis Marques. "Anaesthetics and analgesics used in adult fish for research: A review". Laboratory Animals 53 (2018): 00-00.
    Published • 10.1177/0023677218815199
  22. Félix, Luís M.; Correia, Fernando; Pinto, Pedro A.; Campos, Sónia P.; Fernandes, Telma; Videira, Romeu; Oliveira, M.M.; Peixoto, Francisco P.; Antunes, Luís M.. "Propofol affinity to mitochondrial membranes does not alter mitochondrial function". European Journal of Pharmacology 803 May 15 (2017): 48-56.
    Published • 10.1016/j.ejphar.2017.03.044
  23. Félix, Luís M.; Serafim, Cindy; Martins, Maria J.; Valentim, Ana M.; Antunes, Luís M.; Matos, Manuela; Coimbra, Ana M.. "Morphological and behavioral responses of zebrafish after 24 h of ketamine embryonic exposure". Toxicology and Applied Pharmacology 321 Feb 16 (2017): 27-36.
    Published • 10.1016/j.taap.2017.02.013
  24. Guedes, Silvana R.; Valentim, Ana M.; Antunes, Luis M.. "Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task". Applied Animal Behaviour Science 189 April (2017): 91-97.
    Published • 10.1016/j.applanim.2017.01.012
  25. Antunes, Luis Miguel Joaquim Marques. "Implementation of Human Endpoints in a Urinary Bladder Carcinogenesis Study in Rats". In Vivo 31 6 (2017): 1073-1080.
    Published • 10.21873/invivo.11172
  26. Félix, Luís M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luís M.; Matos, Manuela; Coimbra, Ana M.. "Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish". Toxicology Letters 279 14 July (2017): 1-8.
    Published • 10.1016/j.toxlet.2017.07.888
  27. Félix, L.M.; Antunes, L.M.; Coimbra, A.M.; Valentim, A.M.. "Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine". Psychopharmacology 234 4 (2017): 549-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-85001555685&partnerID=MN8TOARS.
    10.1007/s00213-016-4491-7
  28. Summavielle, Teresa; Venâncio, Carlos; Antunes, Luís. "Ketamine and Mitochondrial Function Response". Anesthesia & Analgesia 122 3 (2016): 918-920.
    Published • 10.1213/ane.0000000000001001
  29. Campos, Sónia; Monteiro, Joaquim; Valenzuela, Belén; Gonçalinho, Helena; de Pinho, Paula Guedes; Fresco, Paula; Félix, Luis; Antunes, Luís. "Evidence of Different Propofol Pharmacokinetics under Short and Prolonged Infusion Times in Rabbits". Basic & Clinical Pharmacology & Toxicology 118 6 (2016): 421-431.
    Published • 10.1111/bcpt.12521
  30. Félix, Luís M.; Vidal, Ana M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luís M.; Campos, Sónia; Matos, Manuela; Monteiro, Sandra M.; Coimbra, Ana M.. "Ketamine-induced oxidative stress at different developmental stages of zebrafish (Danio rerio) embryos". RSC Adv. 6 66 (2016): 61254-61266.
    Published • 10.1039/c6ra08298j
  31. Campos, Sónia; Félix, Luís; Venâncio, Carlos; de Lurdes Pinto, Maria; Peixoto, Francisco; de Pinho, Paula Guedes; Antunes, Luís. "In vivo study of hepatic oxidative stress and mitochondrial function in rabbits with severe hypotension after propofol prolonged infusion". SpringerPlus 5 1 (2016): 1349-1356.
    Published • 10.1186/s40064-016-2970-2
  32. Félix, Luís M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luís M.; Campos, Sónia; Matos, Manuela; Coimbra, Ana M.. "Embryonic Stage-Dependent Teratogenicity of Ketamine in Zebrafish ( Danio rerio )". Chemical Research in Toxicology 29 8 (2016): 1298-1309.
    Published • 10.1021/acs.chemrestox.6b00122
  33. Campos, Sónia P.; de Lurdes Pinto, Maria; Gomes, Gabriela; de Pinho, Paula Guedes; Monteiro, Joaquim A.; Félix, Luis M.; Branco, Paula S.; Ferreira, Luísa M.; Antunes, Luís M.. "Expression of CYP1A1 and CYP1A2 in the liver and kidney of rabbits after prolonged infusion of propofol". Experimental and Toxicologic Pathology 68 9 (2016): 521-531.
    Published • 10.1016/j.etp.2016.07.006
  34. Magalhães, Ana; Valentim, Ana M.; Venâncio, Carlos; Pereira, Mariana; Melo, Pedro; Summavielle, Teresa; Antunes, Luis. "Ketamine alone or combined with midazolam or dexmedetomidine does not affect anxiety-like behaviours and memory in adult Wistar rats". Laboratory Animals 51 2 (2016): 147-159.
    Published • 10.1177/0023677216652380
  35. Valentim, Ana M.; Félix, Luís M.; Carvalho, Leonor; Diniz, Enoque; Antunes, Luís M.; Gong, Zhiyuan. "A New Anaesthetic Protocol for Adult Zebrafish (Danio rerio): Propofol Combined with Lidocaine". PLOS ONE 11 1 (2016): e0147747-e0.
    Published • 10.1371/journal.pone.0147747
  36. Martins, Tânia; Valentim, Ana M.; Pereira, Nuno; Antunes, Luis M.. "Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement". Laboratory Animals 50 6 (2016): 476-488.
    Published • 10.1177/0023677216670686
  37. Summavielle, Teresa; Venâncio, Carlos; Antunes, Luís. "In Response". Anesthesia & Analgesia 122 3 (2016): 918-920.
    Published • 10.1213/ANE.0000000000001001
  38. Ribeiro, Patrícia O.; Antunes, Luis M; Nunes, Catarina S.; Silva, Henrique B.; Cunha, Rodrigo A.; Tomé, Ângelo R.. "The Effects of Different Concentrations of the a2-Adrenoceptor Agonist Medetomidine on Basal Excitatory Synaptic Transmission and Synaptic Plasticity in Hippocampal Slices of Adult Mice". Anesthesia & Analgesia 120 5 (2015): 1130-1137.
    Published • 10.1213/ANE.0000000000000636
  39. Venâncio, Carlos; Félix, Luís; Almeida, Vanessa; Coutinho, João; Antunes, Luís; Peixoto, Francisco; Summavielle, Teresa. "Acute Ketamine Impairs Mitochondrial Function and Promotes Superoxide Dismutase Activity in the Rat Brain". Anesthesia & Analgesia 120 2 (2015): 320-328.
    Published • 10.1213/ANE.0000000000000539
  40. Valentim, A. M.; Guedes, S. R.; Pereira, A. M.; Antunes, L. M.. "Euthanasia using gaseous agents in laboratory rodents". Laboratory Animals 50 4 (2015): 241-253.
    Published • 10.1177/0023677215618618
  41. Santos, C.; Félix, L.; Neves, M.; Coimbra, A.; Valentim, A.M.; Antunes, L.; Gonçalves, C.; et al. "Refinement Techniques in Zebrafish Anaesthesia - Results from a Pilot Study". Microscopy and Microanalysis 21 S5 (2015): 93-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944042002&partnerID=MN8TOARS.
    Published • 10.1017/S1431927615014270
  42. Brás, S.; Georgakis, A.; Ribeiro, L.; Ferreira, D.A.; Silva, A.; Antunes, L.; Nunes, C.S.. "Electroencephalogram-based indices applied to dogs' depth of anaesthesia monitoring". Research in Veterinary Science 97 3 (2014): 597-604.
    Published • 10.1016/j.rvsc.2014.09.017
  43. Ribeiro, Patrícia O.; Silva, Henrique B.; Tomé, Ângelo R.; Cunha, Rodrigo A.; Antunes, Luís M.. "Hippocampal long-term potentiation in adult mice after recovery from ketamine anesthesia". Lab Animal 43 10 (2014): 353-357.
    Published • 10.1038/laban.571
  44. Ribeiro, Patrícia O.; Tomé, Ângelo R.; Silva, Henrique B.; Cunha, Rodrigo A.; Antunes, Luís M.. "Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices". Brain Research 1560 4 (2014): 10-17.
    Published • 10.1016/j.brainres.2014.03.004
  45. Félix, Luís M.; Antunes, Luís M.; Coimbra, Ana M.. "Ketamine NMDA receptor-independent toxicity during zebrafish (Danio rerio) embryonic development". Neurotoxicology and Teratology 41 1 (2014): 27-34.
    Published • 10.1016/j.ntt.2013.11.005
  46. Campos, Sónia; Monteiro, J.; Antunes, Luís; Branco PS; Ferreira LM; Félix L; Almeida, J.M.. "Simultaneous Quantification of Propofol and its Non-Conjugated Metabolites in Several Biological Matrices Using Gas Chromatography/Ion Trap – Mass Spectrometry Method". Journal of Analytical & Bioanalytical Techniques 5 3 (2014): 195-204.
    Published • 10.4172/2155-9872.1000195
  47. Ribeiro PO; Rodrigues PC; Valentim AM; Antunes LM. "A single intraperitoneal injection of ketamine does not affect spatial working, reference memory or neurodegeneration in adult mice: A prospective animal study.". (2013): http://europepmc.org/abstract/med/23736087.
    10.1097/EJA.0b013e3283610321
  48. Brás, S.; Gouveia, S.; Ribeiro, L.; Ferreira, D.A.; Antunes, L.; Nunes, C.S.. "Fuzzy logic model to describe anesthetic effect and muscular influence on EEG Cerebral State Index". Research in Veterinary Science 94 3 (2013): 735-742.
    Published • 10.1016/j.rvsc.2012.12.008
  49. Valentim, Ana M.; Ribeiro, Patrícia O.; Olsson, I. Anna S.; Antunes, Luís M.. "The memory stages of a spatial Y-maze task are not affected by a low dose of ketamine/midazolam". European Journal of Pharmacology 712 1-3 (2013): 39-47.
    Published • 10.1016/j.ejphar.2013.04.027
  50. Venâncio, Carlos; Antunes, Luís; Félix, Luís; Rodrigues, Paula; Summavielle, Teresa; Peixoto, Francisco. "Chronic ketamine administration impairs mitochondrial complex I in the rat liver". Life Sciences 93 12-14 (2013): 464-470.
    Published • 10.1016/j.lfs.2013.08.001
  51. Valentim, A. M.; Olsson, I. A. S.; Antunes, L. M.. "The anaesthetic combination of ketamine/midazolam does not alter the acquisition of spatial and motor tasks in adult mice". Laboratory Animals 47 1 (2013): 19-25.
    Published • 10.1258/la.2012.011179
  52. Ribeiro, Patrícia O.; Rodrigues, Paula C.; Valentim, Ana M.; Antunes, Luís M.. "A single intraperitoneal injection of ketamine does not affect spatial working, reference memory or neurodegeneration in adult mice". European Journal of Anaesthesiology 30 10 (2013): 618-626. http://europepmc.org/abstract/med/23736087.
    Published • 10.1097/eja.0b013e3283610321
  53. Campos, S.; Silva, A.; De Pinho, P.G.; Antunes, L.M.. "Blood propofol concentrations: On demand for pharmacokinetic/ pharmacodynamics models and new measurement automatic technologies". Proceedings of the International Workshop on Veterinary Biosignals and Biodevices, VBB 2012, in Conjunction with BIOSTEC 2012 1 (2012): 18-23.
    Published
  54. Ribeiro, P. O.; Valentim, A. M.; Rodrigues, P.; Olsson, I. A.; Antunes, L. M.. "Apoptotic neurodegeneration and spatial memory are not affected by sedative and anaesthetics doses of ketamine/medetomidine combinations in adult mice". British Journal of Anaesthesia 108 5 (2012): 807-814.
    Published • 10.1093/bja/aes003
  55. Ribeiro, Lénio M; Ferreira, David A.; Brás, Susana; Gonzalo-Orden, Jose M; Antunes, Luis M. "Correlation between clinical signs of depth of anaesthesia and cerebral state index responses in dogs with different target-controlled infusions of propofol". Veterinary Anaesthesia and Analgesia 39 1 (2012): 21-28.
    Published • 10.1111/j.1467-2995.2011.00657.x
  56. Silva, A.; Antunes, L.. "Electroencephalogram-based anaesthetic depth monitoring in laboratory animals". Laboratory Animals 46 2 (2012): 85-94.
    Published • 10.1258/la.2012.011135
  57. Campos, Sónia; Silva, Aura; Pinho, Paula; Bastos, Maria; Branco, Paula; Ferreira, Luisa; Antunes, Luis. "Potential effects of non-conjugated metabolites of propofol in clinical variables". Toxicology Letters 211 2 (2012): S56-S57.
    Published • 10.1016/j.toxlet.2012.03.224
  58. Ribeiro, P.; Silva, A.; Antunes, L.; Gabriel, J.. "Thermal effect during ketamine anaesthesia in laboratorial mice". Thermology International 22 3 (2012): 105-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-85005973806&partnerID=MN8TOARS.
  59. Valentim, A.M.; Summavielle, T.; Antunes, L.M.. "Importance of body temperature and clinical data in behavioral and anesthesia studies". Anesthesiology 116 1 (2012): 226-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-84555218001&partnerID=MN8TOARS.
    10.1097/ALN.0b013e31823cf056
  60. Silva, Aura; Ribeiro, Lénio M; Bressan, Nadja; Oliveira, Pedro; Ferreira, David A.; Antunes, Luís M.. "Dogs mean arterial pressure and heart rate responses during high propofol plasma concentrations estimated by a pharmacokinetic model". Research in Veterinary Science 91 2 (2011): 278-280.
    Published • 10.1016/j.rvsc.2011.01.001
  61. Venancio, C.; Magalhaes, A.; Antunes, L.; Summavielle, T.. "Impaired Spatial Memory after Ketamine Administration in Chronic Low Doses". Current Neuropharmacology 9 1 (2011): 251-255.
    Published • 10.2174/157015911795016912
  62. Silva, Aura; Campos, Sónia; Monteiro, Joaquim; Venâncio, Carlos; Costa, Bertinho; Guedes de Pinho, Paula; Antunes, Luis. "Performance of Anesthetic Depth Indexes in Rabbits under Propofol Anesthesia". Anesthesiology 115 2 (2011): 303-314.
    Published • 10.1097/aln.0b013e318222ac02
  63. Silva, A.; Ferreira, D. A.; Venancio, C.; Souza, A. P.; Antunes, L. M.. "Performance of electroencephalogram-derived parameters in prediction of depth of anaesthesia in a rabbit model". British Journal of Anaesthesia 106 4 (2011): 540-547.
    Published • 10.1093/bja/aeq407
  64. Silva, A.; Campos, S.; Monteiro, J.; Vengncio, C.; Costa, B.; Guedes De Pinho, P.; Antunes, L.. "Performance of anesthetic depth indexes in rabbits under propofol anesthesia: Prediction probabilities and concentration-effect relations". Anesthesiology 115 2 (2011): 303-314. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961024408&partnerID=MN8TOARS.
    10.1097/ALN.0b013e318222ac02
  65. Alves HN; da Silva AL; Olsson IA; Orden JM; Antunes LM. "Anesthesia with intraperitoneal propofol, medetomidine, and fentanyl in rats.". (2010): http://europepmc.org/abstract/med/20819392.
  66. Silva, Aura; Cardoso-Cruz, Hélder; Silva, Francisco; Galhardo, Vasco; Antunes, Luís. "Comparison of Anesthetic Depth Indexes Based on Thalamocortical Local Field Potentials in Rats". Anesthesiology 112 2 (2010): 355-363.
    Published • 10.1097/aln.0b013e3181ca3196
  67. Valentim, Ana M.; Di Giminiani, Pierpaolo; Ribeiro, Patrícia O.; Rodrigues, Paula; Olsson, I. Anna S.; Antunes, Luís M.. "Lower Isoflurane Concentration Affects Spatial Learning and Neurodegeneration in Adult Mice Compared with Higher Concentrations". Anesthesiology 113 5 (2010): 1099-1108.
    Published • 10.1097/aln.0b013e3181f79c7c
  68. Alves, H.N.C.; Da Silva, A.L.M.; Olsson, I.A.S.; Orden, J.M.G.; Antunes, L.M.. "Anesthesia with intraperitoneal propofol, medetomidine, and fentanyl in rats". Journal of the American Association for Laboratory Animal Science 49 4 (2010): 454-459. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956138574&partnerID=MN8TOARS.
    Published
  69. Silva, A.; Cardoso-Cruz, H.; Silva, F.; Galhardo, V.; Antunes, L.. "Comparison of anesthetic depth indexes based on thalamocortical local field potentials in rats". Anesthesiology 112 2 (2010): 355-363. http://www.scopus.com/inward/record.url?eid=2-s2.0-77449114783&partnerID=MN8TOARS.
    10.1097/ALN.0b013e3181ca3196
  70. Valentim, A.M.; Di Giminiani, P.; Ribeiro, P.O.; Rodrigues, P.; Olsson, I.A.S.; Antunes, L.M.. "Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations". Anesthesiology 113 5 (2010): 1099-1108. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049352411&partnerID=MN8TOARS.
    10.1097/ALN.0b013e3181f79c7c
  71. Ferreira DA; Nunes CS; Lobo F; Antunes LM; Amorim P. "Remifentanil bolus dose is a safe procedure to control intense noxious stimuli in hypertensive neurosurgical patients.". (2009): http://europepmc.org/abstract/med/19865053.
  72. Ferreira DA; Nunes CS; Lobo F; Antunes LM; Amorim P. "Remifentanil bolus dose is a safe procedure to control intense noxious stimuli in hypertensive neurosurgical patients.". Med Sci Monit 15 11 (2009): 551-555. http://europepmc.org/abstract/med/19865053.
    Published
  73. Nunes, Catarina S.; Ferreira, David A.; Antunes, Luís; Lobo, Francisco; Santos, Isabel A.; Amorim, Pedro. "Individual effect-site concentrations of propofol at return of consciousness are related to the concentrations at loss of consciousness and age in neurosurgical patients". Journal of Clinical Anesthesia 21 1 (2009): 3-8.
    Published • 10.1016/j.jclinane.2008.06.011
  74. Vilela, Sérgio M.F.; Santos, Dario J.S.L.; Félix, Luis; Almeida, José M.; Antunes, Luis; Peixoto, Francisco. "Are fentanyl and remifentanil safe opioids for rat brain mitochondrial bioenergetics?". Mitochondrion 9 4 (2009): 247-253.
    Published • 10.1016/j.mito.2009.03.002
  75. Ribeiro, L.M.; Ferreira, D.A.; Brás, S.; Castro, A.; Nunes, C.A.; Amorim, P.; Antunes, L.M.. "Correlation between clinical signs of depth of anaesthesia and cerebral state index responses in dogs during induction of anaesthesia with propofol". Research in Veterinary Science 87 2 (2009): 287-291.
    Published • 10.1016/j.rvsc.2009.02.010
  76. Alves, H. C.; Valentim, A. M.; Olsson, I. A. S.; Antunes, L. M.. "Intraperitoneal anaesthesia with propofol, medetomidine and fentanyl in mice". Laboratory Animals 43 1 (2009): 27-33.
    Published • 10.1258/la.2008.007036
  77. Ferreira, D.A.; Nunes, C.S.; Lobo, F.; Antunes, L.M.; Amorim, P.. "Remifentanil bolus dose is a safe procedure to control intense noxious stimuli in hypertensive neurosurgical patients". Medical Science Monitor 15 11 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-71649094130&partnerID=MN8TOARS.
  78. Valentim AM; Alves HC; Olsson IA; Antunes LM. "The effects of depth of isoflurane anesthesia on the performance of mice in a simple spatial learning task.". (2008): http://europepmc.org/abstract/med/18459707.
  79. Antunes, L.M.; Pinto, M.L.; Silva, A.L.; Alves, H.C.. "Accidental ear burns following anaesthesia in mice". Scandinavian Journal of Laboratory Animal Science 35 4 (2008): 299-301.
    Published
  80. de Lurdes Pinto, M.; Rodrigues, P.; Coelho, A.C.; Antunes, L.M.; Gonçalves, C.; Bairos, V.; Antunes, L.. "Technical Report: Mouse fetal blood collection taking the best out of the old needle-syringe method". Scandinavian Journal of Laboratory Animal Science 35 1 (2008): 5-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-44149093833&partnerID=MN8TOARS.
    Published
  81. Ribeiro, Lénio M; Ferreira, David A.; Bressan, Nadja M.; Nunes, Catarina S.; Amorim, Pedro; Antunes, Luis M. "Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol". Research in Veterinary Science 85 2 (2008): 227-232.
    Published • 10.1016/j.rvsc.2007.10.010
  82. Ferreira, David A.; Nunes, Catarina S.; Lobo, Francisco; Casal, Manuela; Antunes, Luís M.; Amorim, Pedro. "Brain tumors may alter the relationship between bispectral index values and propofol concentrations during induction of anesthesia". Journal of Clinical Anesthesia 20 2 (2008): 116-121.
    Published • 10.1016/j.jclinane.2007.09.011
  83. Valentim, A. M.; Alves, H. C.; Silva, A. M.; Olsson, I. A. S.; Antunes, L. M.. "Effects of depth of isoflurane anaesthesia on a cognition task in mice". British Journal of Anaesthesia 101 3 (2008): 434-435.
    Published • 10.1093/bja/aen228
  84. Vilela, Sergio M.; Santos, Dario L.; Félix, Luis M.; Antunes, Luis M; Almeida, L. José M.; Peixoto, Francisco M.. "Brain mitochondrial bioenergetics is differentially affected by anesthetics fentanil and remifentanil". Biochimica et Biophysica Acta (BBA) - Bioenergetics 1777 Jul (2008): S50-S50.
    Published • 10.1016/j.bbabio.2008.05.198
  85. Brás, Susana; Bressan, Nadja ; Ribeiro, Lénio ; Ferreira, D.A.; Antunes, Luís Marques ; Nunes, Catarina Sofia ; BR¿?S, S.; et al. "A step towards effect-site target controlled infusion with propofol in dogs: a ke0 for propofol". Journal of Veterinary Pharmacology and Therapeutics 32 32 (2008): 182-188.
    Published • 10.1111/j.1365-2885.2008.01019.x
  86. Brás, S.; Ribeiro, L.; Ferreira, D.; Antunes, L.; Nunes, C.. "CSI response to high propofol concentrations is related to dog's weight". European Journal of Anaesthesiology 25 Sup 44 (2008): 129-129.
    Published • 10.1097/00003643-200805001-00412
  87. Valentim, A.M.; Alves, H.C.; Olsson, I.A.S.; Antunes, L.M.. "The effects of depth of isoflurane anesthesia on the performance of mice in a simple spatial learning task". Journal of the American Association for Laboratory Animal Science 47 3 (2008): 16-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649149078&partnerID=MN8TOARS.
  88. Antunes, L.; Pinto, M.L.; Silva, A.L.; Alves, H.C.. "Accidental ear burns following anaesthesia in mice". Scandinavian Journal of Laboratory Animal Science 35 4 (2008): 299-301. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449698034&partnerID=MN8TOARS.
  89. Alves, H. C.; Valentim, A. M.; Olsson, I. A. S.; Antunes, L. M.. "Intraperitoneal propofol and propofol fentanyl, sufentanil and remifentanil combinations for mouse anaesthesia". Laboratory Animals 41 3 (2007): 329-336.
    Published • 10.1258/002367707781282767
  90. Bressan, N.; Castro, A.; Brás, S.; Oliveira, H.P.; Ribeiro, L.; Ferreira, D.A.; Antunes, L.; Amorim, P.; Nunes, C.S.. "Synchronization software for automation in anesthesia.". Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2007 (2007): 5298-5301. http://www.scopus.com/inward/record.url?eid=2-s2.0-41149164337&partnerID=MN8TOARS.
  91. Brás, S.; Bressan, N.; Ribeiro, L.; Ferreira, D.A.; Antunes, L.; Nunes, C.S.. "Nonlinear modeling of cerebral state index in dogs.". Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2007 (2007): 537-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-40649085844&partnerID=MN8TOARS.
  92. Ferreira, D.A.; Nunes, C.S.; Antunes, L.M.; Lobo, F.; Amorim, P.; Antunes, L.. "Practical aspects of the use of target controlled infusion with remifentanil in neurosurgical patients: Predicted cerebral concentrations at intubation, incision and extubation". Acta Anaesthesiologica Belgica 57 3 (2006): 265-270. http://www.sarb.be/site/assets/files/1142/06-ferreira.pdf.
    Published
  93. Nunes, Catarina S.; Mendonça, Teresa F.; Antunes, Luís; Ferreira, David A.; Lobo, Francisco; Amorim, Pedro. "Modelling drugs' pharmacodynamic interaction during general anaesthesia: The choice of pharmacokinetic model". IFAC Proceedings Volumes 39 18 (2006): 447-452.
    Published • 10.3182/20060920-3-FR-2912.00080
  94. Nunes, C.S.; Ferreira, D.A.; Lobo, F.; Amorim, P.; Antunes, L.. "Heart Rate times Systolic Pressure has less Influence than Heart Rate on Propofol Induction Amount". Journal of Neurosurgical Anesthesiology 18 4 (2006): 334-335.
    Published • 10.1097/00008506-200610000-00140
  95. Ferreira, D.A.; Nunes, C.S.; Lobo, F.; Antunes, L.; Amorim, P.. "BIS Monitoring during Neurosurgery in Patients with low Glasgow Coma Scale under General Anesthesia". Journal of Neurosurgical Anesthesiology 18 4 (2006): 279-279.
    Published • 10.1097/00008506-200610000-00026
  96. Nunes, C.S.; Mendonça, T.; Ferreira, D.A.; Antunes, L.; Amorim, P.. "The influence on the choice of pharmacokinetic model on the propofol and remifentanil pharmacodynamic interaction". Journal of Neurosurgical Anesthesiology 18 4 (2006): 333-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994399050&partnerID=MN8TOARS.
    10.1097/00008506-200610000-00138
  97. Ferreira, D.A.; Nunes, C.S.; Antunes, L.M.; Santos, I.A.; Lobo, F.; Casal, M.; Ferreira, L.; Amorim, P.. "The effect of a remifentanil bolus on the bispectral index of the EEG (BIS) in anaesthetized patients independently from intubation and surgical stimuli". European Journal of Anaesthesiology 23 4 (2006): 305-310. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644803207&partnerID=MN8TOARS.
    10.1017/S0265021505001997
  98. Ferreira, D.A.; Nunes, C.S.; Lobo, F.; Amorim, P.; Antunes, L.. "Hemodynamic and BIS responses to a large remifentanil bolus are not influenced by obesity and arterial hypertension". Journal of Neurosurgical Anesthesiology 18 4 (2006): 335-335. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026152494&partnerID=MN8TOARS.
    10.1097/00008506-200610000-00141
  99. Ferreira DA; Nunes CS; Antunes L; Lobo F; Amorim P. "Practical aspects of the use of target controlled infusion with remifentanil in neurosurgical patients: predicted cerebral concentrations at intubation, incision and extubation.". (2006): http://europepmc.org/abstract/med/17067138.
  100. Nunes CS; Ferreira DA; Antunes LM; Amorim P. "Regular clinical use bispectral index monitoring may result in lighter depth of anesthesia as reflected in average higher bispectral index values.". (2005): http://europepmc.org/abstract/med/16306760.
    10.1097/00000542-200512000-00042
  101. Ferreira DA; Santos IA; Nunes CS; Amorim P; Antunes LM. "[Hydroxyethyl starch 130/0.4 can be useful to prevent a hemodynamic response to a single dose of remifentanil]". (2005): http://europepmc.org/abstract/med/16363301.
  102. Nunes, Catarina S.; Ferreira, David A.; Antunes, Lu??s; Amorim, Pedro. "Clinical Variables Related to Propofol Effect-Site Concentrations at Recovery of Consciousness After Neurosurgical Procedures". Journal of Neurosurgical Anesthesiology 17 2 (2005): 110-114.
    Published • 10.1097/01.ana.0000163198.02742.9d
  103. Nunes, Catarina S.; Ferreira, David A.; Antunes, Lu??s M.; Amorim, Pedro. "Regular Clinical Use Bispectral Index Monitoring May Result in Lighter Depth of Anesthesia as Reflected in Average Higher Bispectral Index Values". Anesthesiology 103 6 (2005): 1320-1321.
    Published • 10.1097/00000542-200512010-00042
  104. Oliveira, P.; Pires, M.A.; Rodrigues, P.; Ginja, M.; Pires, M.J.; Pires, I.; Cardoso, L.; Antunes, L.; Rodrigues, M.. "Opisthorchis felineus in cat: case report". Arquivo Brasileiro de Medicina Veterinária e Zootecnia 57 4 (2005): 556-558.
    Published • 10.1590/s0102-09352005000400020
  105. Antunes, L. M.; Roughan, J. V.; Flecknell, P. A.. "Excitatory effects of fentanyl upon the rat electroencephalogram and auditory-evoked potential responses during anaesthesia". European Journal of Anaesthesiology 20 10 (2005): 800-808.
    Published • 10.1017/S0265021503001297
  106. Ferreira, D.A.; Nunes, Catarina Sofia ; Antunes, Luis; Santos, Isabel ; Lobo, Francisco ; Casal, Manuela ; Ferreira, Luísa; Amorim, Pedro Pinho. "Remifentanil decreases BIS, an effect independent of intubation and surgical stimuli". European Journal of Anaesthesiology 22 Suppl 34 (2005): 22-29.
    Published • 10.1097/00003643-200505001-00100
  107. Nunes, Catarina Sofia ; Ferreira, D.A.; Casal, Manuela ; Antunes, Luis; Amorim, Pedro Pinho. "Bispectral index during propofol TCI is influenced by patients' demographics". European Journal of Anaesthesiology 22 Supplement (2005): 27-28.
    Published • 10.1097/00003643-200505001-00096
  108. Ferreira, D.A.; Nunes, Catarina Sofia ; Amorim, Pedro Pinho ; Lobo, Francisco ; Antunes, Luís Marques. "Predicted propofol concentrations and BIS in patients with brain tumors". Journal of Neurosurgical Anesthesiology 117 (4) (2005): 257-258.
    Published • 10.1097/01.ana.0000187782.86578.38
  109. Nunes, Catarina Sofia ; Ferreira, D.A.; Lobo, Francisco ; Amorim, Pedro Pinho ; Antunes, Luis. "Propofol predicted effect-site concentrations at loss of consciousness are strongly correlated with baseline patient heart rate". Journal of Neurosurgical Anesthesiology 117 (4) (2005): 253-253.
    Published • 10.1097/01.ana.0000187772.07664.5a
  110. Nunes, Catarina Sofia ; Mendonça, Teresa ; Ferreira, D.A.; Antunes, Luis; Amorim, Pedro Pinho. "Propofol and remifentanil pharmacokinetics/pharmacodynamics during induction may predict recovery of anesthesia". Journal of Neurosurgical Anesthesiology 117 (4) (2005): 252-252.
    Published • 10.1097/01.ana.0000187771.69545.10
  111. DA, Ferreira; CS, Nunes; F, Lobo; L, Antunes; P, Amorim. "Bis May Alert For Cerebral Ischemia". Journal of Neurosurgical Anesthesiology 17 4 (2005): 257-257.
    Published • 10.1097/01.ana.0000187781.78954.31
  112. Ferreira, D.A.; Santos, I.A.; Nunes, C.S.; Amorim, P.; Antunes, L.M.. "Hydroxyethyl starch 130/0.4 can be useful to prevent a hemodynamic response to a single dose of remifentanil,E1 hidroxietilalmidón (HES) 130/0.4 puede ser úitil en la prevención de la respuesta hemodinámica a un bolus de remifentanilo.". Revista española de anestesiología y reanimación. 52 9 (2005): 550-553. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644873546&partnerID=MN8TOARS.
  113. Nunes, C.S.; Ferreira, D.A.; Mendonça, T.F.; Amorim, P.; Antunes, L.M.. "Neuro-fuzzy techniques to model pharmacodynamic interactions between anesthetic drugs on the bispectral index: A preliminary study". Journal of Intelligent and Fuzzy Systems 16 1 (2005): 15-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-21244449188&partnerID=MN8TOARS.
    Published
  114. Nunes, C.S.; Ferreira, D.A.; Antunes, L.M.; Amorim, P.. "Regular clinical use bispectral index monitoring may result in lighter depth of anesthesia as reflected in average higher bispectral index values [10]". Anesthesiology 103 6 (2005): 1320-1321. http://www.scopus.com/inward/record.url?eid=2-s2.0-28044457184&partnerID=MN8TOARS.
  115. Oliveira, P.; Pires, M.A.; Rodrigues, P.; Ginja, M.; Pires, M.J.; Pires, I.; Cardoso, L.; Antunes, L.; Rodrigues, M.. "Opisthorchis felineus in cat: Case report". Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 57 4 (2005): 556-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-31544453871&partnerID=MN8TOARS.
    10.1590/S0102-09352005000400020
  116. Nunes, Catarina Sofia ; Ferreira, D.A.; Antunes, Luis; Amorim, Pedro Pinho. "Variables Associated with Propofol Predicted Effect Site Concentrations at Awakening in Neurosurgical Patients". Journal of Neurosurgical Anesthesiology 16 4 (2004): 364-364.
    Published • 10.1097/00008506-200410000-00101
  117. Nunes, Catarina Sofia ; Ferreira, D.A.; Antunes, Luis; Lobo, Francisco ; Amorim, Pedro Pinho. "Propofol Predicted Effect Concentrations at Loss of Consciousness are Strongly Correlated with Predicted Concentrations at Recovery of Consciousness". Journal of Neurosurgical Anesthesiology 16 4 (2004): 342-343.
    Published • 10.1097/00008506-200410000-00053
  118. Antunes, L. M.; Roughan, J. V.; Flecknell, P. A.. "Effects of different propofol infusion rates on EEG activity and AEP responses in rats". Journal of Veterinary Pharmacology and Therapeutics 26 5 (2003): 369-376.
    Published • 10.1046/j.1365-2885.2003.00499.x
  119. Antunes, L.M.; Golledge, H.D.; Roughan, J.V.; Flecknell, P.A.; Antunes, Luis M; Golledge, Huw DR; Roughan, Johnny V; Flecknell, Paul A. "Comparison of electroencephalogram activity and auditory evoked responses during isoflurane and halothane anaesthesia in the rat.". Veterinary anaesthesia and analgesia 30 1 (2003): 15-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141886202&partnerID=MN8TOARS.
    Published • 10.1046/j.1467-2995.2003.00085.x
  120. Hedenqvist, P.; Orr, H.E.; Roughan, J.V.; Antunes, L.M.; Flecknell, P.A.. "Anaesthesia with ketamine/medetomidine in the rabbit: Influence of route of administration and the effect of combination with butorphanol". Veterinary Anaesthesia and Analgesia 29 1 (2002): 14-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-23244446536&partnerID=MN8TOARS.
    10.1046/j.1467-2987.2001.00058.x
  121. Hedenqvist, P.; Roughan, J. V.; Antunes, L.; Orr, H.; Flecknell, P. A.. "Induction of anaesthesia with desflurane and isoflurane in the rabbit". Laboratory Animals 35 2 (2001): 172-179. http://lan.sagepub.com/content/35/2/172.
    Published • 10.1258/0023677011911561
  122. Antunes, L.M.; Roughan, J.V.; Flecknell, P.A.. "Evaluation of auditory evoked potentials to predict depth of anaesthesia during fentanyl/fluanisone-midazolam anaesthesia in rats". Veterinary Anaesthesia and Analgesia 28 4 (2001): 196-203.
    Published • 10.1046/j.1467-2987.2001.00059.x
  123. Hedenqvist, P.; Roughan, J.V.; Orr, He; Antunes, L. M.. "Assessment of ketamine/medetomidine anaesthesia in the New Zealand White rabbit". Veterinary Anaesthesia and Analgesia 28 1 (2001): 18-25.
    Published • 10.1046/j.1467-2995.2001.00019.x
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2018 - 2018 ANALGESIC MONITORING IN EXPERMENTAL ANIMALS
Supervisor
Medicina Veterinária (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2016 - 2016 Estudo e Aplicação da Modelação Farmacocinética do Propofol na Anestesia Alvo-controlada em Medicina Veterinária
Supervisor
2016 - 2016 Towards an understanding of ketamine teratogenicity in zebrafish early development
Co-supervisor
2016 - 2016 Towards an understanding of ketamine teratogenicity in zebrafish early development
Co-supervisor
Ciências Químicas e Biológicas (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2016 - 2016 DESENVOLVIMENTO DE DIFERENTES SISTEMAS PARA AUTOMAÇÃO DA DETEÇÃO DE MOVIMENTOS E LOCALIZAÇÃO DE ROEDORES EM ESTUDOS COMPORTAMENTAIS
Supervisor
Medicina Veterinária (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2016 - 2016 IMPLEMENTAÇÃO DE NOVOS PROTOCOLOS ANESTÉSICOS EM PEIXE-ZEBRA
Supervisor
Medicina Veterinária (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2014 - 2014 Recuperação Anestésica em Clinica de Animais de Companhia
Supervisor
2014 - 2014 Avaliação do efeito analgésico da buprenorfina adicionada à bupivacaína em bloqueios dos nervos ciático e femoral no período peri-operatório
Supervisor
2014 - 2014 Echocardiographic assessment of medetomidine-induced cardiovascular effects in cats
Supervisor
2013 - 2013 El uso del “indice de estado cerebral” como herramienta para evaluar la profundidad anestesica en perros anestesiados con propofol
Supervisor
2013 - 2013 Effects of ketamine administration in rats: mitochondrial and functional changes in brain and liver
Co-supervisor
2013 - 2013 Ketamine and Medetomidine Effects on Brain: Behavioral, Histopathological and Electrophysiological Studies
Supervisor
2013 - 2013 Estudo das potenciais vantagens da analgesia epidural em cirurgia ortopédica
Supervisor
2012 - 2012 Behavioural effects of anesthetics in mice
Supervisor
2012 - 2012 STUDY AND APPLICATION OF PROPOFOL PHARMACOKINETIC MODELING TO TARGET CONTROLLED ANESTHESIA IN VETERINARY MEDICINE
Supervisor
Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2011 - 2011 Desarrollo de Técnicas anestésica en Animales de Laboratório
Supervisor
2011 - 2011 Electroencephalogram-derived indexes for precise control of animal anesthesia
Supervisor
2011 - 2011 Bases anatómicas para os principais acessos cirúrgicos ao membro torácico do cão (Anatomical basis for the main surgical approaches to the forelimb of the dog)
Co-supervisor
2010 - 2010 Automation in veterinary anaesthesia: Modelling and Control
Co-supervisor
2010 - 2010 Assessment of propofol anesthesia in the rabbit
Supervisor
2010 - 2010 Neurotoxic Effects of Propofol Anaesthesia
Supervisor
Neurociências (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2009 - 2009 The behavioural and histopathological effects of ketamine / medetomidine anaesthetic combination in the brain of adult mice
Supervisor
2009 - 2009 Recent advances in veterinary anaesthesiology: Towards closed-loop systems
Supervisor
2009 - 2009 Avaliação do efeito analgésico da cetamina em doses sub-anestésicas no período peri-operatório
Supervisor
2009 - 2009 Ketamine and medetomicide effets in brain: behavioral histopatological and electrophysiological studies
Supervisor
Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2009 - 2009 Behavioural effects of anaesthetics in mice-risk of cognitive alterations
Supervisor
Ciências Veterinárias (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009 Eeg- Derived Indexes in Animals: Towards Closed-loop Anaesthesia
Co-supervisor
Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2007 - 2007 Anaesthetic evaluation of remifentanil during routine neurosurgical procedures: haemodynamic responses and the bispectral index of the electroencephalogram
Supervisor
2007 - 2007 Effects of hetamine administration in rats: mitochondrial and functional changes in brain and liver
Co-supervisor
Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2007 - 2007 Anaesthetic Evaluation of Remifentanil During Routine Neurosurgical Procedures: Haemodynamic Responses and the Bispectral Index of the Electroencephelogram
Supervisor
Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2003 - 2003 Improvements on Laboratory Animals Anaesthesia Protocols Based on Behavioural Studies
Supervisor
Outro ramo (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal

Association member

Society Organization name Role
2007/01 - Current Laboratory Animal Ltd
2003/12 - Current Sociedade Portuguesa de Ciências de Animais de Laboratório (SPCAL)
Distinctions

Award

2010 INOV@UTAD - 1º prémio - equipe Anestheasy (Com Aura Maia Silva)
2010 I2P - 3º prémio - equipe Anestheasy (Com Aura Maia Silva)
Fundación Cotec, Spain
1997 Menção honrosa no Prémio PFIZER de Ciências Veterinárias
Sociedade Portuguesa de Ciências Veterinárias, Portugal
1991 Prémio Friskies
1990 Prémio Waltham