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NELSON ANDRADE, Requimte Researcher (CEEC - FCT 2023) He completed his PhD in Metabolism - Clinical and Experimental in 07/2019, at the Faculty of Medicine, University of Porto and Master in Consumer Sciences and Nutrition in 10/2013, at the Faculty of Sciences, University of Porto. With more than 20 articles in international journals and magazines in several fields. Specialization in Metabolic Syndrome - Proven experience in an animal model of metabolic syndrome (fructose) - Knowledge and practice with apparent permeability model (Ussing chambers, Transwells - ex vivo and in vitro - monolayer and organoids) - Knowledge in intestinal histology and microbiota (in vivo). Knowledge and practice in molecular biology (Rt qPCR) and with Flavor Receptors (STRs) and nutrient transport, especially fructose and glucose and their intestinal transporters - with bioactive compounds (polyphenols), especially involved in intestinal sugar transport - Induction of oxidative stress on intestinal sugar transport (in several cell lines). Focus on by-products and sustainability, with emphasis on bioactive potential in the context of obesity, diabetes, and cancer. Works in the area(s) of Medical and Health Sciences with emphasis on Nutrition and Dietetics, Natural Sciences, Biological Sciences, Biochemistry, Metabolism, and Bioactive Compounds.
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Identification

Personal identification

Full name
NELSON VINICIUS MELO ANDRADE

Citation names

  • ANDRADE, NELSON

Author identifiers

Ciência ID
DA1F-7025-5FBE
ORCID iD
0000-0003-2600-8599
Scopus Author Id
57195055835

Addresses

  • Al. Prof. Hernani Monteiro, Faculdade de Medicina FMUP, unidade de Bioquímica, 4200319, Porto, PORTO, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Nutrition, Dietetics
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biochemical Research Methods
  • Agrarian Sciences - Agrarian and Food Biotechnology - Agricultural Biotechnology and Food Biotechnology
  • Medical and Health Sciences - Health Sciences - Public and Environmental Health

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2)
Portuguese (Mother tongue)
Education
Degree Classification
2021/07/05 - 2021/07/09
Concluded
 Organoids systems for the study of infection - 1º Ed. 2021 (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/07/17
Concluded
 Metabolismo - Clínica e Experimentação (Doutoramento)
Major in Sem especialidade
Universidade do Porto Faculdade de Medicina, Portugal
"The effect of dietary polyphenols upon the intestinal absorption of fructose: relevance for metabolic syndrome" (THESIS/DISSERTATION)
2016/06/06 - 2016/07/01
Concluded
 Laboratory Animal Science - C Category - Researcher and Leader (Título de Habilitação de Coordenação Científica)
Major in Continuing Training Course
Universidade do Porto Faculdade de Medicina, Portugal
 18
2013
Concluded
 Ciências do Consumo e Nutrição (Mestrado)
Major in Sem especialização
Universidade do Porto Faculdade de Ciências, Portugal
"Obesity and Food consumption: A cross-sectional analysis from the Portuguese National Health Survey" (THESIS/DISSERTATION)
2009/01/01
Concluded
 Nutrition (Licenciatura)
Universidade Federal da Bahia Escola de Nutrição, Brazil
 15
Affiliation

Science

Category
Host institution 		Employer
2023/07/01 - Current Contracted Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2019/08/01 - Current Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2019/11/01 - 2023/06/30 Postdoc (Research) REQUIMTE LAQV Porto, Portugal
2011/10/12 - 2011/11/04 Contracted Researcher (Research) Governo do Brasil - FNDE/ Universidade Federal da Bahia - UFBA/ Nações Unidas - UN, São Tomé and Príncipe

Teaching in Higher Education

Category
Host institution 		Employer
2018/05/01 - Current Tutor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal

Other Careers

Category
Host institution 		Employer
2013/10/01 - 2013/12/31 Assistente (Técnico Superior de Saúde) Fundação Hospitalar de Saúde de Aracaju, FHS, Brasil, Brazil
2009/06/01 - 2009/12/01 Assistente (Técnico Superior de Saúde) Companhia Vale do Rio Doce, Divisão de Fertilizantes, Brazil

Others

Category
Host institution 		Employer
2021/09/01 - Current Professor Pós Graduação CDTNutri - Pós Graduação em Nutrição na Obesidade, Cirurgia Bariátrica e Metabólica, Brazil
CDTNutri - Pós Graduação em Nutrição na Obesidade, Cirurgia Bariátrica e Metabólica, Brazil
2019/04/01 - Current Professor Pós Graduação Instituto HIB, Brazil
Instituto HIB, Brazil
Projects

Contract

Designation Funders
2023/07/01 - 2029/06/30 Assessing the effect of coffee by-product extract on the metabolic syndrome: an approach to reduce waste and obtain a functional coffee silverskin ingredient with enhanced health benefits
2022.08492.CEECIND/CP1724/CT0012
10.54499/2022.08492.CEECIND/CP1724/CT0012
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Other

Designation Funders
2022/01/01 - 2024/12/31 Podem os subprodutos do café diminuir o risco da síndrome metabólica? Uma abordagem abrangente para a redução do desperdício e valorização dos benefícios para a saúde.
PTDC/SAU-NUT/2165/2021
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference abstract
  1. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Coffee silverskin: A sustainable alternative with antidiabetic potential (KEYNOTE CONVIDADA)". Paper presented in IX Workshop de Engenharia de Biossistemas ¿ WEB 9.0, Rio de Janeiro, 2023.
  2. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Coffee silverskin: A potential value-added by-product with similar effects as coffee on sugar metabolism (COMUNICAÇÃO ORAL)". Paper presented in ASIC2023: 29th ASIC Conference, Hanoi, 2023.
    Published
  3. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Inhibition of GLUT2 gene expression by coffee and silverskin extracts (COMUNICAÇÃO ORAL)". Paper presented in ICP 2023 - 31st International Conference on Polyphenols, Nantes, 2023.
    Published
  4. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Rita C. Alves; Martel, Fátima. "Can coffee silverskin be a sustainable coffee by-product with a beneficial effect on type II diabetes mellitus? (COMUNICAÇÃO ORAL)". Paper presented in SPF Meeting 2023 (53rd Meetong of the Portuguese Society of Farmacology, 41st Meeting of Clinical Farmacology and 22nd Meeting of Toxicology), Coimbra, 2023.
    Published
  5. ANDRADE, NELSON; Juliana A. Barreto Peixoto; Silva, Cláudia; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Antitumoral activity of green and roasted coffee extracts (COMUNICAÇÃO ORAL)". Paper presented in SPF Meeting 2023 (53rd Meetong of the Portuguese Society of Farmacology, 41st Meeting of Clinical Farmacology and 22nd Meeting of Toxicology), Coimbra, 2023.
    Published
  6. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Pele de prata do café como promissor antidiabético (COMUNICAÇÃO ORAL)". Paper presented in Webinar Luso-Brasileiro "Café, mais do que uma bebida", Porto, 2022.
    Published
  7. ANDRADE, NELSON; Juliana A. Barreto Peixoto; Silva, Cláudia; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Atividade antitumoral de extratos de café (verde e torrado) e de pele de prata (COMUNICAÇÃO ORAL)". Paper presented in Webinar Luso-Brasileiro "Café, mais do que uma bebida", Porto, 2022.
    Published
  8. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Rita C. Alves; Martel, Fátima. "Antidiabetic potential of cherry stem infusion through inhibitory effects on intestinal sugar uptake (COMUNICAÇÃO ORAL)". Paper presented in SPF Meeting 2022 (LII Reunião da Sociedade Portuguesa de Farmacologia, XL Reunião de Farmacologia Clínica e XXI Reunião de Toxicologia), Porto, 2022.
    Published
  9. ANDRADE, NELSON; Juliana A. Barreto Peixoto; Silva, Cláudia; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Rita C. Alves; Martel, Fátima. "Effects of a coffee roast by-product extract on different tumoral lines: a "sustainable" call for further studies (COMUNICAÇÃO ORAL)". Paper presented in SPF Meeting 2022 (LII Reunião da Sociedade Portuguesa de Farmacologia, XL Reunião de Farmacologia Clínica e XXI Reunião de Toxicologia), Porto, 2022.
    Published
  10. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Influence of a coffee silverskin extract on glucose intestinal transporters: an apparent synergism between caffeine and 5-O-caffeoylquinic acid (COMUNICAÇÃO ORAL)". Paper presented in ISEKI e-conference on Food Texture, Quality, Safety and Biosecurity in the Global Bio-economy, Timisoara, 2021.
    Published
  11. Juliana Peixoto; ANDRADE, NELSON; Susana Machado; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Rita C. Alves; Martel, Fátima. "Effect of coffee silverskin upon sugars intestinal uptake by Caco-2 cells (COMUNICAÇÃO ORAL)". Paper presented in 51ª Reunião da Sociedade Portuguesa de Farmacologia, 39ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia, Lisboa, 2021.
    Published
  12. Juliana Peixoto; Álvarez-Rivera, Gerardo; Rita C. Alves; Anabela S. G. Costa; ANDRADE, NELSON; Andreia Moreira; Cifuentes, Alejandro; et al. "Antioxidant potential and phenolic profile of cherry stem infusions (COMUNICAÇÃO ORAL)". Paper presented in ISEKI e-conference on Food Quality and Texture in Sustainable Production and Healthy Consumption, Bucareste, 2020.
    Published
  13. Juliana Peixoto; ANDRADE, NELSON; Susana Machado; Anabela S. G. Costa; Martel, Fátima; M. Beatriz P.P. Oliveira; Rita C. Alves. "Is intestinal glucose uptake affected by the chlorogenic acids and caffeine contents of a coffee silverskin extract? (COMUNICAÇÃO ORAL - short)". Paper presented in ISEKI e-conference on Food Quality and Texture in Sustainable Production and Healthy Consumption, Bucareste, 2020.
    Published
Conference paper
  1. Juliana A. Barreto Peixoto; Nelson Andrade; Susana Machado; Anabela S. G. Costa; Maria Beatriz P. P. Oliveira; Fátima Martel; Rita C. Alves. "Influence of Coffee Silverskin, Caffeine and 5-Caffeoylquinic Acid on Sugar Uptake Using Caco-2 Cells: A Preliminary Study". 2021.
    10.3390/Foods2021-11011
Conference poster
  1. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Scaling up the recovery of bioactive compounds with antidiabetic potential from coffee silverskin: lab vs. pilot scale". Paper presented in XXVII Encontro Luso Galego de Química, 2023.
  2. Diana Melo Ferreira; ANDRADE, NELSON; Maria Antónia Nunes; Joana C. Lobo ; Cláudia Silva; Martel, Fátima; Maria Beatriz P. P. Oliveira; Rita Carneiro Alves. "Atividade antitumoral de um extrato de bagaço de azeitona em células de cancro da mama, pâncreas e colorretal". Paper presented in Encontro Ciência 2023, Aveiro, Portugal, 2023.
  3. ANDRADE, NELSON; Juliana A. Barreto Peixoto; Silva, Cláudia; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Coffee silverskin extract as a potential colorectal cancer preventive agent: a comparison with roasted coffee". Paper presented in ICP 2023 - 31st International Conference on Polyphenols, 2023.
  4. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Silva, Cláudia; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Antitumor potential of coffee silverskin and roasted coffee extracts upon a colorectal cancer cell line". Paper presented in Ciência 2023 - Encontro com a Ciência e Tecnologia em Portugal, 2023.
  5. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Can coffee silverskin be as promising as green coffee on type II diabetes prevention?". Paper presented in XVI Encontro de Química dos Alimentos, 2022.
  6. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Rita C. Alves; Martel, Fátima. "Cherry stem infusion: a potential beverage to restrain intestinal glucose uptake". Paper presented in XVI Encontro de Química dos Alimentos, 2022.
  7. ANDRADE, NELSON; Juliana A. Barreto Peixoto; Silva, Cláudia; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Comparison of roasted coffee and coffee silverskin extracts: effects on a malignant pancreatic cell line (AsPC-1)". Paper presented in XVI Encontro de Química dos Alimentos, 2022.
  8. Juliana A. Barreto Peixoto; ANDRADE, NELSON; Machado, Susana; Anabela S. G. Costa; M. Beatriz P.P. Oliveira; Martel, Fátima; Rita C. Alves. "Coffee silverskin as a sustainable ingredient to prevent type 2 diabetes". Paper presented in Transcolab Summit - Trends in grain-based foods, 2022.
Journal article
  1. Gonçalves, Joana; Pinto, Sara; Carmo, Francisca; Silva, Cláudia; Andrade, Nelson; Martel, Fátima. "Additive Cytotoxic and Colony-Formation Inhibitory Effects of Aspirin and Metformin on PI3KCA-Mutant Colorectal Cancer Cells". International Journal of Molecular Sciences 25 10 (2024): 5381. http://dx.doi.org/10.3390/ijms25105381.
    10.3390/ijms25105381
  2. Juliana A. Barreto-Peixoto; Cláudia Silva; Anabela S. G. Costa; Gerardo Álvarez-Rivera; Alejandro Cifuentes; Elena Ibáñez; M. Beatriz P. P. Oliveira; et al. "A Prunus avium L. Infusion Inhibits Sugar Uptake and Counteracts Oxidative Stress-Induced Stimulation of Glucose Uptake by Intestinal Epithelial (Caco-2) Cells". Antioxidants (2023): https://doi.org/10.3390/antiox13010059.
    10.3390/antiox13010059
  3. Mafalda R. Couto; Nelson Andrade; Fernando Magro; Martel F. "Bile salts and proinflammatory cytokines inhibit MCT1-mediated cellular uptake of butyrate and interfere with its antiproliferative properties". Experimental Cell Research 429 2 (2023): 113670-113670. http://dx.doi.org/10.1016/j.yexcr.2023.113670.
    10.1016/j.yexcr.2023.113670
  4. Sílvia M. Torres; Francisca P. Carmo; Luís C. Monteiro; Cláudia Silva; Nelson Andrade; Martel F. "Gallic acid markedly stimulates GLUT1-mediated glucose uptake by the AsPC-1 pancreatic cancer cell line". Canadian Journal of Physiology and Pharmacology 101 2 (2023): 90-105. http://dx.doi.org/10.1139/cjpp-2022-0260.
    10.1139/cjpp-2022-0260
  5. Juliana A. Barreto Peixoto; Nelson Andrade; Susana Machado; Anabela S. G. Costa; Maria Beatriz P. P. Oliveira; Fátima Martel; Rita C. Alves. "Green/Roasted Coffee and Silverskin Extracts Inhibit Sugar Absorption by Human Intestinal Epithelial (Caco-2) Cells by Decreasing GLUT2 Gene Expression". Foods (2022): https://doi.org/10.3390/foods11233902.
    10.3390/foods11233902
  6. Nelson Andrade. "Can coffee silverskin be a useful tool to fight metabolic syndrome?". Frontiers in Nutrition 9 (2022): http://dx.doi.org/10.3389/fnut.2022.966734.
    10.3389/fnut.2022.966734
  7. Juliana A. Barreto Peixoto; Nelson Andrade; Susana Machado; Anabela S. G. Costa; Helder Puga; Maria Beatriz P. P. Oliveira; Fátima Martel; Rita C. Alves. "Valorizing Coffee Silverskin Based on Its Phytochemicals and Antidiabetic Potential: From Lab to a Pilot Scale". Foods (2022): https://doi.org/10.3390/foods11121671.
    10.3390/foods11121671
Distinctions

Award

2021 Melhor apresentação Oral
ISEKI-Food Association, Austria
2019 Melhor Poster
Universidade do Porto Faculdade de Medicina, Portugal
2016 Short oral-communication prize - Poster Mode
XV CONGRESSO DE NUTRIÇÃO E ALIMENTAÇÃO - SOCIEDADE PORTUGUESA DE NUTRIÇÃO, Portugal