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Carla Sofia Garcia Fernandes is a researcher at the Research Center CIIMAR and assistant professor of Organic and Medicinal Chemistry of the Faculty of Pharmacy of the University of Porto. She obtained her degree in Pharmaceutical Sciences at the University of Porto in 2002; Master in Quality Control - Scientific Area in Drug Substances and Medicinal Plants, from the same University in 2006; and PhD in Pharmaceutical and Medicinal Chemistry from the same University in 2012. Current research interests include design of chiral compounds with potential biological activity, development of synthetic methodologies for obtaining bioactive chiral compounds, studies of enantioselectivity and structure-activity relationship, synthesis of chiral stationary phases, analytical and preparative enantiomeric separation of diverse racemic mixtures by liquid chromatography and membranes, studies of chiral recognition mechanisms. Participates and/or participated as Researcher in 19 projects. She is author/co-author of 2 books, 4 book chapters, 64 papers in international scientific periodicals with referees (h-index 24), 15 abstracts in conference proceedings, 1 application note and several oral, poster and electronic communications. Has 1 patent registered. She supervised/co-supervised 2 PhD student, 13 master students as well as 28 undergraduate students. She is currently supervising/co-supervising 3 PhD students, 5 master students and 3 undergraduate student. Participated in various activities of scientific dissemination and has been a member of organizing and scientific committees of national courses. From September 2018, she is Member of the Scientific Committee of the Master Degree in Pharmaceutical Chemistry at the Faculty of Pharmacy of Porto. Organized 17 events. Has received 4 awards and/or honors.
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Identification

Personal identification

Full name
Carla Sofia Garcia Fernandes

Citation names

  • Fernandes, Carla

Author identifiers

Ciência ID
DD1A-28E2-66CD
ORCID iD
0000-0003-0940-9163

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences - Analytical Chemistry
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Elementary (A2) Upper intermediate (B2) Upper intermediate (B2)
French Elementary (A2) Intermediate (B1) Elementary (A2) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2012
Concluded
 Doutoramento em Ciencias Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
"Synthesis of Chiral Derivatives of Xanthones: Application as HPLC Stationary Phases and Potential Bioactive Agents in Pharmaceutical and Medicinal Chemistry" (THESIS/DISSERTATION)
 Aprovado com distinção
2006
Concluded
 Controlo de Qualidade (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
"Síntese de Fases Estacionárias Quirais "tipo Pirkle" Derivadas de Núcleos Xantónicos para a Resolução de Fármacos Racémicos em HPLC" (THESIS/DISSERTATION)
 Muito Bom
2002
Concluded
 Ciências Farmacêuticas (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
"Ciências Farmacêuticas" (THESIS/DISSERTATION)
 14 valores
Affiliation

Science

Category
Host institution 		Employer
2016/04/01 - Current Researcher (Research) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
2014/01/01 - Current Researcher (Research) Universidade do Porto, Portugal
Centro Interdisciplinar de Investigação Marinha e Ambiental da Madeira, Portugal
2004/09/01 - 2013/12/31 Researcher (Research) Universidade do Porto, Portugal
Centro de Química Medicinal (CEQUIMED), Portugal
(...)

Teaching in Higher Education

Category
Host institution 		Employer
2012/10/12 - Current Assistant Professor (University Teacher) Universidade do Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2006/10/12 - 2012/10/12 Invited Assistant (University Teacher) Universidade do Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
2008/06/28 - 2008/09/14 Research trainee Universidade Federal de São Carlos, Brazil
Universidade Federal de São Carlos - Departamento de Química, Brazil
2004/01/15 - 2006/09/30 Pharmacist Farmácia da Boa Hora, Portugal
2002/07/15 - 2004/01/15 Pharmacist Farmácia Macedo Sucessor, Portugal
2002/01/01 - 2002/05/01 Research trainee (ERASMUS) Faculty of Medicine, Autonomous University, Spain
2001/11/01 - 2002/01/01 Pharmacist Practice Farmácia da Boa Hora, Portugal
Projects

Contract

Designation Funders
2019/03/01 - Current Chiral derivatives of xanthones and flavonoids: synthesis and biological activity evaluation
CHIRALBIOACTIVE-PI-3RL-IINFACTS-2019
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
Ongoing
2018/07 - Current Antimicrobials from the sea: models for innovative agents to revert multidrug resistance
POCI-01-0145-FEDER-028736
POCI-01-0145-FEDER-028736
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Ongoing
2021/03/01 - 2024/08/31 EnantioTox - Enantioselective ecotoxicity and bioaccumulation of psychoactive substances
PTDC/CTA-AMB/6686/2020
Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/03/16 - 2022/09/15 NIAF- Sustainable antifouling agents: from grape wastes to the sea with the green chemistry leading the way
PTDC/CTA-AMB/0853/2021
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/03/16 - 2022/09/15 Anti-incrustantes sustentáveis: dos desperdícios da uva para o Mar, com a Química Verde a liderar o caminho.
PTDC/CTA-AMB/0853/2021
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/02 - 2021/09/30 Antimicrobials from the sea: innovative agent models to reverse multidrug resistance
PTDC/SAU-PUB/28736/2017
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016/01 - 2019/12 NOVELMAR - Novel marine products with biotechnological applications
NORTE-01-0145-FEDER-000035
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Concluded
2016/06/01 - 2019/06/01 Navegando por fungos associados a organismos marinhos: bioprospeção e síntese de metabolitos secundários e análogos como agentes quimioterápicos
PTDC/MAR-BIO/4694/2014
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Fundação Ensino e Cultura Fernando Pessoa, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/04 - 2019/04 Synthesis of new chiral derivatives of xanthones and antimicrobial evaluation
CHIRALXANT-CESPU_2018
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
Concluded
2017/04 - 2018/04 Chiral Bioactive Substances in the Environment
ChiralDrugs_CESPU_2017
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
Concluded
2010/06 - 2013/11 Molecular and nanotechnology-based approaches to improve the antitumor activity of small molecules
Provided by PTCRIS: 100930
100930
PTDC/SAU-FCF/100930/2008
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/09 - 2013/09 Chiral xanthones: Synthesis, biological evaluation and molecular docking as inhibitors of P-glycoprotein (Pgp), phospholipase A2 (PLA2) and cicloxygenases (COX-1 and COX-2)
IJUP, Investigação Científica na Pré-graduação
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Universidade do Porto

Banco Santander Totta
Concluded
2010/06 - 2013/06 Molecular and nanotechnology-based approach to improve the antitumor activity of small molecules
PTDC/SAU-FCF/1000930/2008
Researcher
Centro de Química Medicinal (CEQUIMED), Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009/01 - 2011/01 Chiral xanthones derivatives: synthesis, enantiomeric resolution, anti-inflammatory and antioxidant evaluations
10-GCQF-CICS-09
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2009/01 - 2011/01 Chiral xanthones derivatives: synthesis, enantiomeric resolution, anti-inflammatory and antioxidant evaluations
10-GCQF-CICS-09
 Cooperativa de Ensino Superior Politécnico e Universitário
2008/01 - 2011/01 Small Molecules as Antitumor and Anti-infective Agents
4.1.3/Capes/CPLP-Grices 00770 29/05/08
Researcher
Centro de Química Medicinal (CEQUIMED), Portugal
Concluded
2009/09 - 2010/12 Chiral Xanthones: Synthesis, Structure Elucidation, Enantiomeric Purity and Antioxidant and Anti-inflammatory Activities
IPG_2009 Investigação Científica na Pré-graduação
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Universidade do Porto

Banco Santander Totta
Concluded
2007/09 - 2008/12 Chiral Xanthone Derivatives: Synthesis, Structural Elucidation and Biological Activities
IPG_2007_11 Investigação Científica na Pré-graduação
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Universidade do Porto

Caixa Geral de Depositos
Concluded

Other

Designation Funders
2022/01/01 - Current Sustainable antifouling agents: from grape wastes to the sea with the green chemistry leading the way
PTDC/CTA-AMB/0853/2021
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Ongoing
2021/03/01 - Current Enantioselective ecotoxicity and bioaccumulation of psychoactive substances
PTDC/CTA-AMB/6686/2020
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Ongoing
2020/01/01 - Current Projeto Estratégico do CIIMAR
UIDB/04423/2020 and UIDP/04423/2020
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Ongoing
2019/01/01 - 2019/12 Projeto Estratégico do CIIMAR
UID/Multi/04423/2019
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/06 - 2019/06 Navigating through marine-derived fungi: bioprospection and synthesis of bioactive secondary metabolites and analogues as chemotherapic agents
PTDC/MAR-BIO/4694/2014
Researcher
Concluded
2016/01 - 2018/12 Projeto Estratégico do CIIMAR
UID/Multi/04423/2015
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/03 - 2017/03 Enantioseletive synthesis of chiral derivatives of xanthones and evaluation of anti-inflammatory activity
COXANT-CESPU-2016
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Concluded
2014/01 - 2015/01 CEQUIMED
Pest-OE/SAU/UI4040/2014
Researcher
Centro de Química Medicinal (CEQUIMED), Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Tiritan, Maria Elizabeth; Pinto, Madalena Maria; Fernandes, Carla. Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition. Basel, Switzerland: Molecules, MDPI. 2020.
  2. Fernandes, Carla; Madalena M. M. Pinto; Ana Paula Almeida; Andreia Palmeira; Carlos Afonso; Gisela Adriano; Honorina Cidade; et al. Manual de Trabalhos Laboratoriais de Química Orgânica e Farmacêutica. Porto, Portugal: Lidel. 2011.
Book chapter
  1. Tiritan, M.E.; M Pinto, M.M.; Fernandes, Carla. "Pirkle Type". In Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications. John Wiley & Sons, Inc., 2023.
    In press
  2. Fernandes, Carla; Emília Sousa; Madalena Pinto; Sara Cravo. "Determination of partition coefficients of sulfonamides by reverse-phased chromatography". In In Afonso, C.A & Simão D.P (Eds), Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 51-55. Royal Society of Chemistry, 2016.
  3. Fernandes, Carla; Honorina Cidade; Sara Cravo; Emília Sousa; Madalena M. M. Pinto. "Analysis of racemic and (S)-ibuprofen". In In Afonso, C.A & Simão D.P (Eds), Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 46-50. Royal Society of Chemistry, 2016.
  4. Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Ana Rita Ribeiro. "Chiral Pharmaceuticals". In In Kirk-Othmer Encyclopedia of Chemical Technology, 1-28. John Wiley & Sons, Inc., 2016.
Conference abstract
  1. Teixeira, Joana; Phyo, Y.Z.; Tiritan, M. E.; Cravo, S.; Palmeira, A.; Gales, L.; Silva, A. M. S.; et al. "Stationary phases for liquid chromatography comprising two chiral moieties: synthesis, enantioresolution performance and recognition mechanisms". Paper presented in 13º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2020.
  2. Pinto, M.M.M.; Tiritan, M.E.; Fernandes, Carla. "Chiral xanthone derivatives: synthesis, biological activities and analytical applications". Paper presented in 5th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-5) and 5th International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-5), Cappadocia, 2019.
  3. Ribeiro, A. R. L.; Coelho, M.M.; Sousa, J. C. G.; Silva, A. M. T.; Fernandes, Carla; Tiritan, M. E.. "Enantiomeric profile of chiral pharmaceuticals and drugs of abuse in the environment.". Paper presented in 15th International Symposium on Persistent Toxic Substances, Muttenz, 2018.
  4. Do Carmo, J.P.; Phyo, Y.Z.; Palmeira, A.; Fernandes, Carla; Tiritan, M. E.; Kijoa, A.; Afonso, C.; Pinto, M.M.M.. "Enantioresolution, chiral recognition mechanisms and binding of xanthone derivatives on immobilized human serum albumin by liquid chromatography.". Paper presented in XXIV Encontro Luso-Galego de Química, porto, 2018.
  5. Phyo, Y.Z.; Fernandes, Carla; Tiritan, M. E.; Cravo, S.; Silva, A.M.S.; Kijoa, A.; Pinto, M.M.M.. "New chiral selectors for liquid chromatography based on xanthone derivatives.". Paper presented in 11th International Symposium on Drug Analysis and 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, 2018.
  6. Ribeiro, J.; Fernandes, Carla; Tiritan, M. E.; Pinto, M.M.M.. "Chiral stationary phases based on amylose and cellulose derivatives". Paper presented in 11th Meeting of Young Researches of University of Porto, Porto, 2018.
  7. Do Carmo, J.P.; Fernandes, Carla; Tiritan, M. E.; Afonso, C.; Pinto, M.M.M.. "Chiral recognition of xanthone derivatives on human serum albumin stationary phase: effect of chromatographic conditions". Paper presented in 11th Meeting of Young Researches of University of Porto, Porto, 2018.
  8. Leite, C.; Fernandes, Carla; Tiritan, M. E.; Pinto, M.M.M.. "Synthesis of a xanthone derivative by a multi-step pathway via benzophenone.". Paper presented in 11th Meeting of Young Researches of University of Porto, Porto, 2018.
  9. Carvalhal, F.; Almeida, J.; Sousa, E.; Fernandes, Carla; Vasconcelos, V.; Pinto, M.M.M.; Correia-da-Silva, M.. "Combat marine macrofouling: synthesis and in vivo evaluation of nature-inspired compounds.". Paper presented in 11th Meeting of Young Researches of University of Porto, Porto, 2018.
  10. Fernandes, Carla; Tiritan, M. E.; Pinto, M.M.M.. "New brush-type chiral stationary phases based on xanthone derivatives for liquid chromatography.". Paper presented in 10º Encontro Nacional de Cromatografia, Bragança, Porto, 2017.
  11. Freitas, B.; Fernandes, Carla; Tiritan, M.E.; Silva, A.M.S.; Pinto, M.M.M.. "Strategy for synthesis of chiral derivatives of xanthones in enantiomerically pure form.". Paper presented in 10th Meeting of Young Researches of University of Porto, Porto, 2017.
  12. Lopes, A.; Martins, E.; Silva, R.; Fernandes, Carla; Palmeira, A.; Remião, F.; Pinto, M.M.M.; Sousa, E.. "Small Chiral Molecules as potential P-gp Modulators: Synthesis and Studies of Enantioselectivity.". Paper presented in 10th Meeting of Young Researches of University of Porto, Porto, 2017.
  13. Carraro, M. L.; Fernandes, Carla; Tiritan, M. E.; Silva, A.M.S.; Pinto, M.M.M.. "Synthesis and enantiomeric purity evaluation of new chiral derivatives of xanthones for enantioselectivity studies in antitumor activity". Paper presented in 9th Meeting of Young Researches of University of Porto, Porto, 2016.
  14. Silva, B.; Fernandes, Carla; Pinto, M.M.M.; Bastos, M. L.; Guedes-de-Pinho, P.; Remião, F.. "Direct HPLC enantioresolution and evaluation of the enantiomeric ratio of synthetic cathinones on “Legal Highs"". Paper presented in 9th Meeting of Young Researches of University of Porto, Porto, 2016.
  15. Santos, A.; Soares, J.; Cravo, S.; Tiritan, M.E.; Fernandes, Carla; Afonso, C.; Pinto, M.M.M.. "Determination of the lipophilicity of chiral derivatives of xanthones: comparison of methods.". Paper presented in 9th Meeting of Young Researches of University of Porto, Porto, 2016.
  16. Silva, A.S.; Phyo, Y.Z.; Tiritan, M. E.; Silva, A. M. S.; Fernandes, Carla; Pinto, M.M.M.. "Development and evaluation of a new chiral stationary phase for liquid chromatography". Paper presented in 9th Meeting of Young Researches of University of Porto, Porto, 2016.
  17. Silva, B.; Fernandes, Carla; Pinto, M.M.M.; Bastos, M. L.; Valente, M. J.; Pinho, P. G.; Remião, F.. "Study of the citotoxicity of the enantiomersof 3,4-methylenodioxipirovalerone (MDPV)". Paper presented in Sociedade Portuguesa de Farmacologia, Porto, 2016.
  18. Santos, A.; Fernandes, Carla; Palmeira, A.; Tiritan, M. E.; Afonso, C.; Pinto, M.M.M.. "Resolution of chiral xanthones by HPLC and docking studies". Paper presented in IJUP12 – 5th Meeting of Young Researchers of U. Porto, Porto, 2012.
  19. Ramos, I.; Fernandes, Carla; Tiritan, M.E.; Afonso, C.; Pinto, M.M.M.; Lúcio, M.; Pinto, P.C.A.G.; Saraiva, M.L.M.F.S.; Reis, S.. "Chiral xanthone derivatives: Synthesis, physicochemical properties and anti-inflammatory activity determination". Paper presented in 5th Meeting of Young Researchers of U. Porto, Porto, 2012.
  20. Brandão, P.; Fernandes, Carla; Pinto, M.M.M.; Tiritan, M. E.; Afonso, C.; Cass, Q.. "Efficient Method for Evaluation of the Enantiomeric Purity of Chiral Xanthone Derivatives.". Paper presented in 4th Meeting of Young Researchers of U. Porto, Porto, 2011.
  21. Leitão, L.; Pozzi, A.; Noronha-Matos, J.B.; Pinto, A.; Teixeira, I.; Fernandes, Carla; Pinto, M.M.M.; Oliveira, L.; Correia-De-Sá, P.. "Nerve conduction blockade of xanthone derivatives is not due to membrane stabilizing properties". Paper presented in 2º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2009.
  22. Luís Leitão; Angelo Pozzi; José Bernardo Noronha-Matos; Ana Pinto; Inês Teixeira; Fernandes, Carla; Madalena M. M. Pinto; Laura Oliveira. "Nerve conduction blockade of xanthone derivatives is not due to membrane stabilizing properties". Paper presented in 2nd Meeting of Young Researchers of U. Porto, Porto, 2009.
  23. Fernandes, Carla; Sousa, M. E.; Tiritan, M. E.; De Lima, V.; Pinto, M.M.M.. "Chiral Xanthones: Synthesis and Structural Elucidation". Paper presented in 4th Transmediterranean Colloquium on Heterocyclic Chemistry, Aaveiro, 2006.
  24. Fernandes, Carla; Emília Sousa; Maria Elizabeth Tiritan; Virgínia de Lima; Madalena M. M. Pinto. "Chiral Xanthones: Synthesis and Structural Elucidation". Paper presented in 4th Transmediterranean Colloquium on Heterocyclic Chemistry, Aveiro, 2006.
Conference paper
  1. Barbara Silva; Joana Saraiva Rodrigues; Joana Paiva Miranda; Ana Sofia Almeida; Carla Fernandes; Paula Guedes de Pinho; Fernando Remião. "Metabolism of Cathinones in Functional Hepatocyte-like Cells Derived from Human Neonatal Mesenchymal Stem Cells: An Enantioselectivity Approach". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
    Published • 10.3390/ECMC2022-13302
  2. F. Durães; Cravo, S.; J. Freitas-Silva; N. Szemerédi; P. Martins-da-Costa; E. Pinto; Maria Elizabeth Tiritan; et al. "Chiral derivatives of xanthones: enantioselectivity in the reversal of antimicrobial resistance mechanisms". Paper presented in 14th National Organic Chemistry Meeting (14ENQO)/7th National Medicinal Chemistry Meeting (7ENQT), 2022.
    Published
  3. Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "A view of Medicinal Chemistry through the looking glass: enantioselectivity studies with chiral derivatives of xanthones". Paper presented in 14th National Organic Chemistry Meeting (14ENQO)/7th National Medicinal Chemistry Meeting (7ENQT), 2022.
    Published
  4. M. M. Coelho; Fernandes, Carla; F. Remião; Maria E. Tiritan. "Enantioresolution of promethazine and its metabolites for enantiomeric profile in metabolic studies". Paper presented in 14th National Organic Chemistry Meeting (14ENQO)/7th National Medicinal Chemistry Meeting (7ENQT), 2022.
    Published
  5. Almeida, Ana Sofia; F. Remião; Fernandes, Carla. Corresponding author: Fernandes, Carla. "Enantioseparation and racemization of MDPV by Liquid Chromatography". Paper presented in APCF-TOXRUN International Congress 2022, 2022.
    Published
  6. A. Pérez-Pereira; A. Carvalho; B. Castro; J. Carrola; Fernandes, Carla; Tiritan, M. E.; C. Ribeiro. "Sublethal ecotoxicity assays of na emergente psychoactive substance in Daphnia magna". Paper presented in APCF-TOXRUN International Congress 2022, 2022.
    Published
  7. Silva, Barbara; Fernandes, Carla; Pinho, Paula; Remião, Fernando. "Synthetic cathinones: Chiral resolution and enantioselectivity studies". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06331
  8. B. Silva; Fernandes, Carla; P.G. Pinho; Fernando Remiao. "Enantioselective absorption of cathinones by intestinal epithelial: studies in Caco-2 cells". Paper presented in Eurotox 2019, Helsinki, Filand, 2019.
    Published
  9. Silva, B.; Fernandes, C.; Pinto, M.; Guedes de Pinho, P.; Remião, F.. "Enantioresolution of pentedrone and methylone and in vitro dopaminergic SH-SY5Y cytotoxicity studies". Paper presented in Eurotox 2019, Helsinki, 2019.
    10.1016/j.toxlet.2018.07.030
  10. Fernandes, Carla; Phyo, Ye; Ribeiro, João; Cravo, Sara; Tiritan, Maria; Silva, Artur; Kijjoa, Anake; Pinto, Madalena. "Dual application of chiral derivatives of xanthones in medicinal chemistry and liquid chromatography". Paper presented in 4th International Electronic Conference on Medicinal Chemistry, 2018.
    10.3390/ecmc-4-05604
  11. Bárbara Silva; Fernandes, Carla; Madalena M. M. Pinto; Paula Guedes de Pinho; Fernando Remião. "Enantioresolution of pentedrone and methylone and in vitro dopaminergic SH-SY5Y cytotoxicity studies". Paper presented in Eurotox 2018, Brussels, 2018.
  12. Zin, War War; Prompanya, Chadaporn; Fernandes, Carla; Cravo, Sara; Pinto, Madalena; Kijjoa, Anake. "Chiral Liquid Chromatography in Analysis of the Stereochemistry of Marine Natural Compounds: Contribution for Medicinal Chemistry". Paper presented in 3rd International Electronic Conference on Medicinal Chemistry, 2017.
    doi:10.3390/ph11010018
  13. Fernandes, Carla; Palmeira, Andreia; Ramos, Inês; Carneiro, Carlos; Afonso, Carlos; Tiritan, Maria; Cidade, Honorina; et al. "Chiral Derivatives of Xanthones: Investigation of Enantioselectivity as Inhibitors of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin". Paper presented in 2nd International Electronic Conference on Medicinal Chemistry, 2016.
    10.3390/ph10010020
  14. Lopes, Ana; Martins, Eva; Silva, Renata; Fernandes, Carla; Palmeira, Andreia; Remião, Fernando; Pinto, Madalena; Sousa, Emília. "Studying the influence of stereochemistry in P-gp modulation: case-study with thioxantones". Paper presented in 2nd International Electronic Conference on Medicinal Chemistry, 2016.
    10.3390/ph10010020
  15. Fernandes, Carla; Álvaro Santos; José Soares; Sara Cravo; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "An Example of the Key Role of HPLC in Medicinal Chemistry: Determination of Lipophilicity of a Xanthone Derivatives Library". Paper presented in 11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry, Porto, 2015.
    10.3390/ph9010015
  16. Fernandes, Carla; Carraro, Letícia; Silva, Ana; Veloso, Cláudia; Tiritan, Maria; Silva, Artur; Pinto, Madalena. "Synthesis and enantiomeric purity evaluation of a new small library of promising bioactive chiral derivatives of xanthones". Paper presented in 1st International Electronic Conference on Medicinal Chemistry, 2015.
    10.3390/ph9010014
  17. Fernandes, Carla; Pedro Brandão; Maria Elizabeth Tiritan; Carlos Afonso; Quezia B. Cass; Madalena M. M. Pinto. "Efficient Methodology for Synthesis of Chiral Xanthone Derivatives in Enantiomerically Pure Form". Paper presented in 2nd National Meeting on Medicinal Chemistry, Coimbra, 2010.
  18. Ana Pinto; Fernandes, Carla; Inês Teixeira; Maria Elizabeth Tiritan; Angelo Pozzi; José Bernardo Noronha-Matos; Luís Leitão; et al. "Chiral amino alcohol xanthone derivatives: synthesis, structural elucidation and biological activities". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, 2008.
  19. Fernandes, Carla; Maria Elizabeth Tiritan; Quezia B. Cass; Madalena M. M. Pinto. "Synthesis and HPLC determination of the enantiomeric purity of valinol xanthone derivatives using macrocyclic antibiotic-based chiral stationary phases". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, 2008.
  20. Maria Elizabeth Tiritan; Fernandes, Carla; Quezia B. Cass; Madalena M. M. Pinto. "Synthesis of L and D leucinol xanthone derivatives and HPLC determination of the enantiomeric purity by chiral stationary phase ristocetin A". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, 2008.
  21. Inês Teixeira; Fernandes, Carla; Ana Pinto; Maria Elizabeth Tiritan; Madalena M.M. Pinto. "Synthesis and structural elucidation of 2-carboxyxanthone derivatives". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, 2008.
  22. Emília Sousa; Maria Elizabeth Tiritan; Fernandes, Carla; Virgínia de Lima; Madalena M. M. Pinto; Maria Elizabeth Tiritan; Virgínia Lima. "Synthesis of Chiral Xanthone Derivatives". Paper presented in 16th International Conference on Organic Synthesis, Mérida, 2006.
Conference poster
  1. Coelho, Maria Miguel; Silva, Bárbara; Almeida, Ana Sofia; Fernandes, Carla; Remião, Fernando; Tiritan, Maria Elizabeth. "Enantioselective analytical methods for monitoring in vitro studies of promethazine monitoring in vitro studies of promethazine". Paper presented in 33rd International Symposium on Chirality, 2023.
  2. Pérez-Pereira, Ariana; Carvalho, Ana Rita; Castro, Bruno B.; Carrola, João Soares; Fernandes, Carla; Tiritan, Maria Elizabeth; Ribeiro, Cláudia. Corresponding author: Ribeiro, Cláudia. "3,4-Methylenedioxypyrovalerone (MDPV) sublethal ecotoxicity assay on the microcrustacean Daphnia magna". Paper presented in SETAC Europe 33rd Annual Meeting, 2023.
  3. Almeida, Ana Sofia; Silva, Bárbara; Silva, João Pedro; Remião, Fernando; Fernandes, Carla. "Evaluation of stereochemical stability and enantioselectivity of MDPV enantiomers on SH-SY5Y human neuronal cells". Paper presented in IJUP 2023, 2023.
  4. Ribeiro, Cláudia; Pérez-Pereira, Ariana; Ribeiro, Ondina; Costa, Ana; Gonçalves, Virgínia M. F.; Fernandes, Carla; Castro, Bruno B.; et al. Corresponding author: Ribeiro, Cláudia. "Enantioselectivity in Toxicity of Amphetamine, 3,4-Methylenedioxymethamphetamine and Methylenedioxypyrovalerone on Greshwater Organisms (Daphnia magna and Danio rerio)". Paper presented in SETAC EUROPE 33RD ANNUAL MEETING, 2023.
  5. Ribeiro, Cláudia; Pereira, Ariana; Ribeiro, Ondina; Costa, Ana; Gonçalves, Virgínia M. F.; Fernandes, Carla; Castro, Bruno B.; et al. "Enantioselectivity in Toxicity of Smphetamine, 3,4-Methylenedioxymethamphetamine and Methylenedioxypyrovalerone on Greshwater Organisms (Daphnia magna and Danio rerio)". Paper presented in SETAC EUROPE 33RD ANNUAL MEETING, 2023.
  6. A.S. Almeida; B. Silva; Cravo, S.; F. Remião; Fernandes, Carla. "Development and validation of a UHPLC-UV method for MDPV quantification to evaluate enantioselectivity on their absorption using the Caco-2 cell line". Paper presented in 12º Encontro Nacional de Cromatografia & XIV WARPA, 2022.
  7. R. Ribeiro; L. Costa; E. Pinto; E. Sousa; Fernandes, Carla. "From the bottom of ocean to the lab: synthetic strategies of cyclic peptide marine-derived". Paper presented in XXVI Encontro Galego-Portugués de Química, 2022.
  8. A.S. Almeida; B. Silva; F. Remião; Fernandes, Carla. "Synthesis and structure elucidation of metabolites of the synthetic cathinones pentedrone and methylone for further metabolism studies". Paper presented in XXVI Encontro Luso-Galego de Química, 2022.
  9. Coelho, M.M.; Fernandes, Carla; F. Remião; Elizabeth Tiritan. "Semi-preparative enantioresolution of promethazine and its metabolites for enantiomeric profile in metabolic studies". Paper presented in 12th International Symposium on Drug Analysis & 32nd International Symposium on Pharmaceutical and Biomedical Analysis, 2022.
  10. A.S. Almeida; Fernando Remião; Fernandes, Carla. "Semi-preparative enantioresolution, racemization and cytotoxicity studies with MDPV enantiomers". Paper presented in The Blue Think Conference (BTC), 2022.
  11. Coelho, M.M.; Fernandes, Carla; F. Remião; Elizabeth Tiritan. "Enantioresolution of promethazine and its metabolites for metabolic studies". Paper presented in The Blue Think Conference (BTC), 2022.
  12. R. Ribeiro; E. Pinto; E. Sousa; Fernandes, Carla. "Marine cyclic peptides with antimicrobial activity: synthesis and structure elucidation". Paper presented in The Blue Think Conference (BTC), 2022.
  13. B. Cerqueira; Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis and structure elucidation of new compounds containing nitro groups". Paper presented in IJUP2022 - 15th Meeting of Young Researches of University of Porto, 2022.
  14. F. Durães; Cravo, S.; J. Freitas-Silva; N. Szemerédi; Elizabeth Tiritan; P. Martins-da-Costa; E. Pinto; et al. "Chiral xanthones reversing antimicrobial resistance: enantioselectivity in efflux pump inhibition". Paper presented in 3rd Molecules Medicinal Chemistry Symposium, 2022.
  15. R. Ribeiro; E. Pinto; E. Sousa; Fernandes. "Towards total synthesis of marine cyclic peptide with antimicrobial activity". Paper presented in BYT, 2022.
  16. Pérez-Pereira, Ariana; Carvalho, Ana Rita; Castro, Bruno B.; Carrola, João soares; Fernandes, Carla; Tiritan, Maria Elizabeth; Ribeiro, Cláudia. Corresponding author: Pérez-Pereira, Ariana. "Sublethal and sub-chronic ecotoxicity of five synthetic cathinones in two aquatic organisms". Paper presented in SETAC Europe 32nd Annual Meeting, 2022.
  17. A. Pérez-Pereira; A. Carvalho; B. Castro; J. Carrola; Fernandes, Carla; Elizabeth Tiritan; C. Ribeiro. "Sublethal and sub-chronic ecotoxicity assays of five synthetic cathinones in two aquatic organisms". Paper presented in SETAC EUROPE, 32nd Annual Meeting, 2022.
  18. P. Vedovello; Fernandes, Carla; Elizabeth Tiritan; C.M. Paranhos. "Evaluation of enantiomeric compounds sorption by Pirkle-type chiral selector based on polymer membranes". Paper presented in GEP-SLAP2022 Congress (XVI Meeting of the Specialized Group of Polymers – GEP 2022 and XVII Latin American Symposium of Polymers - SLAP 2022, 2022.
  19. A.S. Almeida; Fernando Remiao; Fernandes, Carla. "Semi-preparative enantioresolution of MDPV enantiomers and racemization study by liquid chromatography". Paper presented in IJUP2022 - 15th Meeting of Young Researches of University of Porto, 2022.
  20. Pérez-Pereira, Ariana; Carvalho, Ana Rita; Castro, Bruno B.; Carrola, João soares; Fernandes, Carla; Tiritan, Maria Elizabeth; Ribeiro, Claudia. "Sublethal ecotoxicity assays of an emergent psychoactive substance in Daphnia magna". Paper presented in APCF-TOXRUN International Congress 2022, 2022.
  21. A. Pérez-Pereira; A. Carvalho; B. Castro; J. Carrola; Fernandes, Carla; Elizabeth Tiritan; C. Ribeiro. "Sublethal ecotoxicity assays of na emergente psychoactive substance in Daphnia magna". Paper presented in APCF-TOXRUN International Congress, 2022.
  22. A.S. Almeida; F. Remião; Fernandes, Carla. "Enantioseparation and racemization of MDPV by Liquid Chromatography". Paper presented in APCF-TOXRUN International Congress 2022, 2022.
  23. R. Ribeiro; E. Pinto; E. Sousa; Fernandes, Carla. "Towards total synthesis of a marine cyclic peptide with antimicrobial activity". Paper presented in 14th National Organic Chemistry Meeting (14ENQO)/7th National Medicinal Chemistry Meeting (7ENQT), 2022.
  24. F. Durães; Cravo, S.; J. Freitas-Silva; N. Szemerédi; P. Martins-da-Costa; E. Pinto; Elizabeth Tiritan; et al. "Chiral derivatives of xanthones: enantioselectivity in the reversal antimicrobial resistance mechanisms". Paper presented in 14th National Organic Chemistry Meeting (14ENQO)/7th National Medicinal Chemistry Meeting (7ENQT), 2022.
  25. M. M. Coelho; Fernandes, Carla; F. Remião; Elizabeth Tiritan. "Enantioresolution of promethazine and its metabolites for enantiomeric profile in metabolic studies". Paper presented in 14th National Organic Chemistry Meeting (14ENQO)/7th National Medicinal Chemistry Meeting (7ENQT), 2022.
  26. A.S. Almeida; F.P. Barbosa; A. Cunha; Fernandes, Carla; Madalena M. M. Pinto; O. Queirós; Maria E. Tiritan. "Chiral derivatives of chrysin: synthesis and investigation of enantioselectivity as inhibitors of growth of tumor cell lines". Paper presented in Curso Da Química Orgânica aos Fármacos: teoria e prática laboratorial, FFUP, 2021.
  27. Coelho, M.M.; Fernandes, Carla; F. Remião; Maria E. Tiritan. "Enantioseparation of promethazine and its metabolites by chiral LC-UV/Vis". Paper presented in Curso Da Química Orgânica aos Fármacos: teoria e prática laboratorial, FFUP, 2021.
  28. R. Lima; Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis of chitosan conjugates with potential as inhibitors of growth of human tumor cell lines". Paper presented in XXVII Encontro Nacional da Sociedade Portuguesa de Química, 2021.
  29. "Marine-derived xanthone analogues with potential anti-inflammatory activity: total synthesis and structure elucidation". Paper presented in VI Jornadas da Bioquímica, 2021.
  30. "Synthesis of new chiral derivatives of chrysin and enantioselectivity as inhibitors of growth of tumor cell lines". Paper presented in VI Jornadas da Bioquímica, 2021.
  31. "Synthesis of marine-derived xanthone analogues with potential anti-inflammatory activity". Paper presented in 14th Meeting of Young Researches of University of Porto, 2021.
  32. L. Gonçalves; Fernandes, Carla; Maria E. Tiritan. "Development and evaluation of a Pirkle-type chiral stationary phase for flash chromatography". Paper presented in 14th Meeting of Young Researches of University of Porto, 2021.
  33. J. Teixeira; Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis and enantiomeric purity evaluation of new chiral derivatives of xanthones". Paper presented in PyChem (Portuguese Young Chemists Meeting), 2021.
  34. R. Lima; Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis of new chitosan conjugates for pharmaceutical and biomedical applications". Paper presented in PyChem (Portuguese Young Chemists Meeting), 2021.
  35. R. Lima; J. Teixeira; Maria E. Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Chitosan-Derived Marine Polysaccharide as Chemical Substrate to Obtain New Conjugates for Pharmaceutical Applications". Paper presented in VI Jornadas da Bioquímica, 2021.
  36. A.S. Almeida; F.P. Barbosa; A. Cunha; J. Teixeira; Fernandes, Carla; Madalena M. M. Pinto; O. Queirós; Maria E. Tiritan. "Synthesis of new chiral derivatives of chrysin and enantioselectivity as inhibitors of growth of tumor cell lines". Paper presented in VI Jornadas da Bioquímica, 2021.
  37. R. Pereira; J. Teixeira; Maria E. Tiritan; Fernandes, Carla; Madalena M. M. Pinto. "Marine-derived xanthone analogues with potential anti-inflammatory activity: total synthesis and structure elucidation". Paper presented in VI Jornadas da Bioquímica, 2021.
  38. Teixeira, Joana; Phyo, Ye Zaw; Tiritan, Maria Elizabeth; Kijoa, Anake; Pinto, Madalena Maria; Fernandes, Carla. "Enantiomeric purity of new xanthone derivatives comprising two chiral moieties by liquid chromatography on (S,S)-Whelk-O1 column". Paper presented in Analitica 2020, 2020.
  39. Teixeira, Joana; Phyo, Ye Zaw; Tiritan, Maria Elizabeth; Cravo, Sara; Palmeira, Andreia; Kijoa, Anake; Pinto, Madalena Maria; Fernandes, Carla. "Chiral stationary phases based on xanthonic derivatives for liquid chromatography: synthesis, enantioresolution performance and mechanism of chiral recognition". Paper presented in Blue Think Conference, 2020.
  40. Almeida, A. S.; Teixeira, Joana; Fernandes, Carla; Pinto, M.M.M.; Tiritan, M.E.. "Synthesis and structure elucidation of chiral amino acid derivatives of chrysin". Paper presented in 13º Encontro Investigação Jovem da Universidade do Porto, 2020.
  41. João Handel; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis and structure elucidation of new atropisomers based on xanthone derivatives". Paper presented in 13th Meeting of Young Researches of University of Porto, Portugal, 2020.
  42. Gisela Adriano; Ricardo Gonçalves; Joel Pedrosa; Virgínia Gonçalves; Honorina Cidade; Sara Cravo; Fernandes, Carla; et al. "Synthesis of enantiomeric pure chiral derivatives of 4'-methylchrysoeriol". Paper presented in 13th Meeting of Young Researches of University of Porto, Portugal, 2020.
  43. Tony Cardoso; Bárbara Silva; Paula Guedes de Pinho; Fernando Remião; Fernandes, Carla. "Enantioseparation of a series of cathinones derivatives by liquid Chromatography using chiral stationary phases". Paper presented in 13th Meeting of Young Researches of University of Porto, Portugal, 2020.
  44. Phyo, Y.Z.; Teixeira, Joana; Tiritan, M. E.; Cravo, S.; Palmeira, A.; Gales, L.; Silva, A. M. S; et al. "Chiral Derivatives of Xanthones: Dual Application in Medicinal Chemistry". Paper presented in 13º Encontro Nacional em Química Orgânica e 6º Encontro Nacional de Química Medicinal, 2020.
  45. Joana Araújo; Fernandes, Carla; Madalena M. M. Pinto; Maria Elizabeth Tiritan. "Synthesis of Chiral Derivatives of Xanthones with Potential Biological Activity". Paper presented in iMed Conference, Lisbon, Portugal, 2019.
  46. Bárbara Silva; Fernandes, Carla; Paula Guedes de Pinho; Fernando Remião. "Enantioselective absorption of cathinones by intestinal epithelial: studies in Caco-2 cells". Paper presented in Eurotox 2019, Helsinki, Filand, 2019.
  47. Ye' Zaw Phyo; Joana Teixeira; Maria Elizabeth Tiritan; Sara Cravo; Artur M.S. Silva; Anake Kijjoa; Madalena M.M. Pinto; Fernandes, Carla. "New chiral stationary phases for liquid chromatography based on small molecules: development, enantioresolution evaluation and chiral recognition mechanisms". Paper presented in 48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy, 2019.
    10.15278/isms.2017.rg07
  48. Phyo, Ye' Zaw; Teixeira, Joana; Cravo, Sara; Tiritan, Maria Elizabeth; Silva, Artur; Pinto, Maria Madalena; Kijoa, Anake; Fernandes, Carla. "Chiral Stationary Phases based on Small Molecules: Development, Enantioresolution Evaluation and Chiral Recognition Mechanisms". Paper presented in 48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2019.
  49. Joana Teixeira; Ye' Zaw Phyo; João Ribeiro; Bárbara Polónia; Fernandes, Carla; Maria Elizabeth Tiritan; Artur M.S. Silva; Anake Kijjoa; Madalena M.M. Pinto. "Development of liquid chromatography chiral stationary phases for separation of enantiomeric drugs". Paper presented in Escola de Inverno de Farmácia, 4ª edição, Porto, Portugal, 2019.
  50. Joana Araújo; Tânia Boavista; Patrícia Carrega; Fernandes, Carla; Madalena M. M. Pinto; Elizabeth Tiritan. "Synthesis of Chiral Derivatives of Xanthones with Potential Antimicrobial activity". Paper presented in Escola de Inverno de Farmácia, 4ª edição, Porto, Portugal, 2019.
  51. Joana Araújo; Tânia Boavista; Viviana Redondo; Patrícia Carrega; Fernandes, Carla; Madalena M. M. Pinto; Maria Elizabeth Tiritan. "Synthesis of Chiral Derivatives of Xanthones with Potential Antimicrobial Activity". Paper presented in IJUP 2019, 12th Meeting of Young Researches of University of Porto, Porto, Portugal, 2019.
  52. Bárbara Polónia; João Ribeiro; Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Synthesis of carboxyxanthones as suitable building blocks to obtain bioactive derivatives and chiral stationary phases". Paper presented in IJUP 2019, 12th Meeting of Young Researches of University of Porto, Porto, Portugal, 2019.
  53. Joana Teixiera; Fernandes, Carla; Elizabeth Tiritan; Madalena M. M. Pinto. "Synthesis and structure elucidation of new chiral selectors for liquid chromatography". Paper presented in IJUP 2019, 12th Meeting of Young Researches of University of Porto, Porto, Portugal, 2019.
  54. Carlos Afonso; Honorina Cidade; Emília Sousa; Fernandes, Carla; Marta Correia da Silva; Madalena M. M. Pinto. "Estratégias pedagógicas no ensino da química orgânica e farmacêutica em ambiente universitário". Paper presented in VII Encontro da Divisão de Ensino e Divulgação da Química, Vila Nova de Gaia, Portugal, 2018.
  55. Maria Miguel Coelho; João C.G. Sousa; Ana Rita Lado Ribeiro; Fernandes, Carla; Adrián M. T. Silva; Maria Elizabeth Tiritan. "Monitoring of several chiral drugs in the Douro river estuary by LC-MS/MS". Paper presented in XXIV Encontro Luso-Galego de Química, Porto, Portugal, 2018.
  56. Virgínia Gonçalves; Hélder Oliveira; Vera Barbosa; Fernandes, Carla; Madalena M. M. Pinto; Elizabeth Tiritan. "Enantioseparation of xanthone derivatives of proteinogenic amino acids on cellulose tris(3-chloro-4-methylphenylcarbamate) stationary phase". Paper presented in XXIV Encontro Luso-Galego de Química, Porto, Portugal, 2018.
  57. Bárbara Silva; Fernandes, Carla; Madalena M. M. Pinto; Paula Guedes; Fernando Remião. "Enantioresolution of pentedrone and methylone and in vitro dopaminergic SH-SY5Y cytotoxicity studies". Paper presented in EUROTOX 2018, Brussels, Belgium, 2018.
  58. Bárbara Silva; José Augusto Pereira; Fernandes, Carla; Madalena M. M. Pinto; Paula Guedes; Fernando Remião. "Pentedrone and methylone enantiomers: cytotoxicity studies in dopaminergic SH-SY5Y cell line, IPAP18". Paper presented in 1st Global Congress of Pharmacy Faculties, Salamanca, Spain, 2018.
  59. Ye' Zaw Phyo; João Carmo; Andreia Palmeira; Maria Elizabeth Tiritan; Fernandes, Carla; Carlos Afonso; Anake Kijjoa; Madalena M.M. Pinto. "Enantioresolution and docking studies of xanthone derivatives on a human serum albumin stationary phase". Paper presented in 11th International Symposium on Drug Analysis and 29th International Symposium on Pharmaceutical and Biomedical Analysis, DA-PBA 2018, Leuven, Belgium, 2018.
  60. Ye' Zaw Phyo; Sara Cravo; Andreia Palmeira; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M.M. Pinto; Anake Kijjoa; Fernandes, Carla. "New chiral xanthonic stationary phases for liquid chromatography and studies of enantioresolution and chiral recognition mechanisms". Paper presented in First Meeting PhD in Biomedical Sciences, ICBAS, Porto, University of Porto, 2018.
  61. Fernandes, Carla; João Carmo; Andreia Palmeira; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Chiral carboxyxanthone derivatives: enantioselectivity studies in binding interaction with human serum albumin". Paper presented in Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry, MedChemSicily2018, Palermo, Italy, 2018.
  62. Fernandes, Carla; João Ribeiro; Maria Elizabeth Tiritan; Sara Cravo; Artur M.S. Silva; Madalena M. M. Pinto. "Chiral derivatives of xanthones: applications in Medicinal Chemistry and Liquid Chromatography". Paper presented in Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry, MedChemSicily2018, Palermo, Italy, 2018.
  63. Maria Elizabeth Tiritan; Hélder Oliveira; Vera Barbosa; Fernandes, Carla; Artur M.S. Silva; Madalena M. M. Pinto. "Enantioselective syntheses of chiral derivative of xanthones". Paper presented in Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry, MedChemSicily2018, Palermo, Italy, 2018.
  64. Maria Elizabeth Tiritan; Hélder Oliveira; Vera Barbosa; Paolo de Marco; Fernandes, Carla; Madalena M. M. Pinto. "Chiral derivatives of xanthones: the role of stereochemistry on biological activities". Paper presented in Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry, MedChemSicily2018, Palermo, Italy, 2018.
  65. João Carmo; Fernandes, Carla; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Enantioresolution of bioactive compounds on human serum albumin stationary phase". Paper presented in Escola de Inverno de Farmácia, 3ª edição, Porto, Portugal, 2018.
    10.1063/1.4790945
  66. João Ribeiro; Fernandes, Carla; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto. "Development of chiral stationary phases based on small molecules and polymeric derivatives for enantioseparation of chiral drugs". Paper presented in Escola de Inverno de Farmácia, 3ª edição, Porto, Portugal, 2018.
  67. Catarina Leite; Patrícia Barbosa; Krystyna Maslowska; Bárbara Polónia; João Ribeiro; Ye' Zaw Phyo; Fernandes, Carla; et al. "Synthesis of xanthone derivatives: important chemical substrates to obtain bioactive compounds". Paper presented in Escola de Inverno de Farmácia, 3ª edição, Porto, Portugal, 2018.
  68. Ye' Zaw Phyo; Sara Cravo; Maria Elizabeth Tiritan; Anake Kijjoa; Madalena M. M. Pinto; Fernandes, Carla. "Macrocyclic glycopeptide antibiotics: application as chiral selectors for enantioseparation of bioactive compounds". Paper presented in Escola de Inverno de Farmácia, 3ª edição, Porto, Portugal, 2018.
  69. Maria Miguel Coelho; Ana Rita Lado Ribeiro; Fernandes, Carla; Maria Elizabeth Tiritan. "Enantioselective method for quantification of chiral drugs in environmental matrices". Paper presented in IJUP 2018, 11th Meeting of Young Researches of University of Porto, Porto, Portugal, 2018.
  70. Fernandes, Carla; Maria Letícia Carraro; Cláudia Veloso; Maria Elizabeth Tiritan; Sandra Marques; Patrícia M.A. Silva; Hassan Bousbaa; Artur M.S. Silva; Madalena M. M. Pinto. "Carboxyxanthone derivatives: synthesis and effect on human tumor cell lines". Paper presented in 12th National Organic Chemistry Meeting & 5th National Medicinal Chemistry Meeting, Coimbra, Portugal, 2018.
  71. Francisca Carvalhal; Joana Almeida; Emília Sousa; Fernandes, Carla; Vitor Vasconcelos; Madalena M. M. Pinto; Marta Correia da Silva. "Synthesis of new bioinspired antifouling agents". Paper presented in 12th National Organic Chemistry Meeting & 5th National Medicinal Chemistry Meeting, Coimbra, Portugal, 2018.
  72. Maria Elizabeth Tiritan; Hélder Oliveira; Vera Barbosa; Paolo de Marco; Fernandes, Carla; Artur M.S. Silva; Madalena M. M. Pinto. "Synthesis of new chiral derivatives from xanthones coupled with proteinogenic amino acids". Paper presented in 12th National Organic Chemistry Meeting & 5th National Medicinal Chemistry Meeting, Coimbra, Portugal, 2018.
  73. João Ribeiro; Fernandes, Carla; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto. "Preparation of a new chiral stationary phase for liquid chromatography based on a small molecule". Paper presented in 10º Encontro Nacional de Cromatografia, Bragança, Portugal, 2017.
  74. João Carmo; Fernandes, Carla; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Liquid chromatography enantioseparation of xanthone derivatives on a human serum albumin stationary phase". Paper presented in 10º Encontro Nacional de Cromatografia, Bragança, Portugal, 2017.
  75. Ye' Zaw Phyo; Andreia Palmeira; Sara Cravo; Maria Elizabeth Tiritan; Anake Kijjoa; Madalena M. M. Pinto; Fernandes, Carla. "Enantiomeric separation and chiral recognition mechanisms of different macrocyclic glycopeptide-based chiral stationary phases". Paper presented in 10º Encontro Nacional de Cromatografia, Bragança, Portugal, 2017.
  76. Ye' Zaw Phyo; Fernandes, Carla; Maria Elizabeth Tiritan; Sara Cravo; Artur M.S. Silva; Anake Kijjoa; Madalena M. M. Pinto. "Analytical applications of xanthone derivatives as chiral selectors for liquid chromatography". Paper presented in Transmediterranean Colloquium on Heterocyclic Chemistry (TRAMECH IX 2017), Fez, Morocco, 2017.
  77. Fernandes, Carla; Maria Letícia Carraro; Maria Elizabeth Tiritan; Sandra Marques; Patrícia M.A. Silva; Hassan Bousbaa; Artur M.S. Silva; Madalena M. M. Pinto. "Synthesis, enantiomeric purity evaluation and enantioselectivity study on human tumor cell lines of new chiral derivatives of xanthones". Paper presented in EFMC-ASMC'17, Vienna, Austria, 2017.
  78. Catarina Leite; Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Total synthesis and structure elucidation of 3-carboxymethoxyxanthone". Paper presented in IJUP 2017, 10th Meeting of Young Researches of University of Porto, Porto, Portugal, 2017.
  79. João Ribeiro; Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Synthesis and structure elucidation of carboxyxanthone derivative". Paper presented in IJUP 2017, 10th Meeting of Young Researches of University of Porto, Porto, Portugal, 2017.
  80. Hélder Ribeiro; Vera Barbosa; Ana Sofia Malheiro; Sofia Dias; Maria Elizabeth Tiritan; Artur M.S. Silva; Fernandes, Carla; Madalena M. M. Pinto. "Strategy for synthesis of enantiomerically pure xanthones - amino acid derivatives". Paper presented in IJUP 2017, 10th Meeting of Young Researches of University of Porto, porto Portugal, 2017.
  81. João Ribeiro; Ye' Zaw Phyo; Catarina Leite; Fernandes, Carla; Maria Elizabeth Tiritan; Anake Kijjoa; Madalena M. M. Pinto. "Carboxyxanthone derivatives: synthesis and structure elucidation". Paper presented in Escola de Inverno de Farmácia, 2nd ed, Porto, Portugal, 2017.
  82. Hélder Ribeiro; Vera Barbosa; Ana Sofia Malheiro; Sofia Dias; Maria Elizabeth Tiritan; Artur M.S. Silva; Fernandes, Carla; Madalena M. M. Pinto. "Síntese de derivados xantónicos quirais de amino ésteres". Paper presented in Escola de Inverno de Farmácia, 2ª ed, Porto, Portugal, 2017.
  83. Ana Lopes; Eva Ribeiro; Renata Silva; Fernandes, Carla; Andreia Palmeira; Fernando Remião; Madalena M. M. Pinto; Emília Sousa. "Importance of stereochemistry and P-gp modulation in drug development: In vitro studies with chiral thioxanthones". Paper presented in XIX National Congress of Biochemistry, Guimarães, Portugal, 2016.
  84. Maria Elizabeth Tiritan; Fernandes, Carla; Maria Letícia Carraro; Artur M.S. Silva; Madalena M. M. Pinto. "Synthesis of chiral carboxylated xanthone derivatives". Paper presented in Chirality 2016, Heidelberg, Germany, 2016.
  85. Maria Letícia Carraro; Maria Elizabeth Tiritan; Artur M.S. Silva; Fernandes, Carla; Madalena M. M. Pinto. "Resolution and determination of enantiomeric purity of chiral derivatives of xanthones using (S,S)-Whelk-O1 stationary phase". Paper presented in Chirality 2016, Heidelberg, Germany, 2016.
  86. Ana Lopes; M. Piskorska; Renata Silva; Fernandes, Carla; Andreia Palmeira; Fernando Remião; Madalena M. M. Pinto; Emília Sousa. "Studying the influence of stereochemistry in P-gp modulation: case-study with newly synthetized thioxantones". Paper presented in Encontro Anual do Departamento de Ciências Biológicas da Faculdade de Farmácia da Universidade do Porto, Portugal, 2016.
  87. Ye' Zaw Phyo; Ana Sofia Silva; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla; Anake Kijjoa. "Bioactive Chiral Derivatives of Xanthones: Application as Analytical Tools". Paper presented in 1st European Young Chemists Meeting and 5th Portuguese Young Chemists Meeting, Guimarães, Portugal, 2016.
  88. Ana Lopes; Renata Silva; Fernandes, Carla; Fernando Remião; Madalena M. M. Pinto; Emília Sousa. "Chiral Thioxanthones as Promising P glycoprotein Modulators". Paper presented in 1st European Young Chemists Meeting and 5th Portuguese Young Chemists Meeting, Guimarães, Portugal, 2016.
  89. Cláudia Veloso; Maria Letícia Carraro; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla. "Total Synthesis and Structural Elucidation of Carboxyxanthone Derivatives". Paper presented in IJUP 2016, 9th Meeting of Young Researches of University of Porto, Porto, Portugal, 2016.
  90. Ana Lopes; Solida Long; Fernandes, Carla; Madalena M. M. Pinto; Emília Sousa. "Synthesis of new tioxanthone derivatives". Paper presented in IJUP 2016, 9th Meeting of Young Researches of University of Porto, Porto, Portugal, 2016.
  91. Bruno Freitas; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis of new chiral derivatives of xanthones in enantiomerically pure form". Paper presented in IJUP 2016, 9th Meeting of Young Researches of University of Porto, Porto, Portugal, 2016.
  92. Fernandes, Carla; Álvaro Santos; José Soares; Sara Cravo; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "An example of the key role of HPLC in Medicinal Chemistry: determination of lipophilicity of a xanthone derivatives library". Paper presented in 11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry, 2015.
  93. Maria Letícia Carraro; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Otimização da síntese da 2-carboxi-6-metoxixantona: um importante substrato para obtenção de derivados xantónicos quirais". Paper presented in 1º Encontro Científico do NEQ/AAC, Coimbra, Portugal, 2015.
  94. Maria Letícia Carraro; Ana Sofia Silva; Fernandes, Carla; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto. "Promising new antitumor chiral derivatives of xanthones: synthesis and evaluation of enantiomeric purity by HPLC". Paper presented in YES METTING, Young European Scientist Meeting, Porto, Portugal, 2015.
  95. Maria Letícia Carraro; Ana Sofia Silva; Cláudia Veloso; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla. "Promising bioactive chiral derivatives of xanthones using carboxyxanthones as chemical substracts". Paper presented in II Simposio de Jóvens Investigadores de la Sociedad Española de Química Terapéutica, Madrid, Spain, 2015.
  96. Fernandes, Carla; Maria Letícia Carraro; Ana Sofia Silva; Cláudia Veloso; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto. "New bioactive chiral derivatives of xanthones: synthesis and optimization of their xanthonic building block". Paper presented in 7th Spanish-Portuguese-Japanese Organic Chemistry Symposium, Seville, Spain, 2015.
  97. Álvaro Santos; Maria Elizabeth Tiritan; Sara Cravo; Madalena M. M. Pinto; Fernandes, Carla. "RP-HPLC evaluation of the lipophilicity of chiral derivatives of xanthones: correlation between chromatographic and theoretical methods". Paper presented in HPLC 2015, Geneva, Switzerland, 2015.
  98. Ana Sofia Silva; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis of promising bioactive chiral derivatives of xanthones with two stereogenic centres". Paper presented in IJUP 2015 - 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2015.
  99. Cláudia Veloso; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis and structural elucidation of a new carboxyxanthone". Paper presented in IJUP 2015 - 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2015.
  100. Maria Leticia Carraro; Maria Elizabeth Tiritan; Artur M.S. Silva; Madalena M. M. Pinto; Fernandes, Carla. "Total synthesis of fluorinated chiral derivatives of xanthones". Paper presented in IJUP 2015 - 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2015.
  101. Bárbara Silva; Fernandes, Carla; Madalena M. M. Pinto; Paula Guedes de Pinho; Fernando Remião. "Chiral HPLC enantioresolution of synthetic cathinones “Legal Highs”". Paper presented in IJUP 2015 - 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2015.
  102. Álvaro Santos; Sara Cravo; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Estimating the lipophilicity of chiral derivatives of xanthones by RP-HPTLC". Paper presented in IJUP 2015 - 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2015.
  103. Joana Moreira; M. Castro; Fernandes, Carla; Marta Correia da Silva; Emília Sousa; Honorina Cidade; Carlos Afonso; et al. "Plant-derived and synthetic compounds affect the proliferation and metabolic activity of 3T3-L1 preadipocytes". Paper presented in IJUP 2015 - 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2015.
  104. Maria Letícia Carraro; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "New chiral derivatives of xanthones: synthesis and structure elucidation". Paper presented in XX Encontro Luso-Galego de Química, Porto, Portugal, 2014.
  105. Álvaro Santos; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "Log P determination of chiral derivatives of xanthones by reversed-phase liquid chromatography". Paper presented in XX Encontro Luso-Galego de Química, Porto, Portugal, 2014.
  106. Ana Sofia Silva; Cláudia Veloso; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Fernandes, Carla. "New Chiral Derivatives of Xanthones as Analytical Tools: Preliminar Studies". Paper presented in XX Encontro Luso-Galego de Química, Porto, Portugal, 2014.
  107. Cristiana F.M. Gregório; Sara Cravo; Fernandes, Carla; Honorina Cidade; Madalena M. M. Pinto; Eugénia Pinto. "Xanthone derivatives with antifungal potential for mycosis treatment". Paper presented in XX Encontro Luso-Galego de Química, Porto, Portugal, 2014.
  108. Diana Torres; Ana Marques; Sara Monteiro; Carlos Carneiro; Alexandre Santos; Fernandes, Carla; Andreia Palmeira; et al. "Chiral xanthones: Synthesis, biological evaluation and molecular docking as inhibitors of P-glycoprotein (Pgp), phospholipase A2 (PLA2) and cicloxygenases (COX-1 and 2)". Paper presented in IJUP14 – 7th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2014.
  109. Ana Marques; Diana Torres; Sara Monteiro; Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Synthetic strategy to obtain chiral derivatives of xanthones". Paper presented in IJUP13 – 6th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2013.
  110. Fernandes, Carla; Kamonporn Masawang; Madalena Pedro; Hassan Bousbaa; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Search of enantioselectivity on the inhibitory effect of chiral derivatives of xanthones on growth of human tumor cell lines". Paper presented in 3rd National Meeting on Medicinal Chemistry - 1st Portuguese-Spanish-Brazilian Meeting on Medicinal Chemistry, Aveiro, Portugal, 2012.
  111. Carlos Carneiro; Andreia Palmeira; Fernandes, Carla; Maria Elizabeth Tiritan; Salette Reis; Madalena M. M. Pinto. "Chiral derivatives of xanthones as potential anti-inflammatory agents: docking studies with phospholipase, cyclooxygenases-1 and 2". Paper presented in 3rd National Meeting on Medicinal Chemistry - 1st Portuguese-Spanish-Brazilian Meeting on Medicinal Chemistry Aveiro, Portugal, 2012.
  112. Fernandes, Carla; Andreia Palmeira; Carlos Carneiro; Maria Elizabeth Tiritan; Inês Ramos; Paula Pinto; Marlene Lúcio; et al. "Chiral xanthones: Synthesis, biological evaluation and molecular docking as inhibitors of target enzymes of the inflammatory pathways". Paper presented in 6th Brazilian Symposium on Medicinal Chemistry – BrazMedChem2012, Canela, Brazil, 2012.
  113. Fernandes, Carla; Alexandre Santos; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Chiral HPLC method for determination of the enantiomeric purity of new xanthone derivatives". Paper presented in 3PYCheM – 3rd Portuguese Young Chemists Meeting, Porto, Portugal, 2012.
  114. Carlos Carneiro; Sara Monteiro; Fernandes, Carla; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Synthesis and Structural Elucidation of New Chiral Xanthone Derivatives". Paper presented in IJUP12 – 5th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2012.
  115. Fernandes, Carla; Pedro Brandão; Alexandre Santos; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Enantioseparation of seven xanthone derivatives on ten chiral HPLC columns – comparative study". Paper presented in 7º Encontro Nacional de Cromatografia, Porto, Portugal, 2012.
  116. Fernandes, Carla; Andreia Palmeira; Alexandre Santos; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Chiral recognition for xanthone derivatives on a Pirkle-type chiral stationary phase – docking studies". Paper presented in 7º Encontro Nacional de Cromatografia, Porto Portugal, 2012.
    10.1063/1.5028622
  117. Fernandes, Carla; Pedro Brandão; Maria Elizabeth Tiritan; Quezia B. Cass; Madalena M. M. Pinto. "Application of Polysaccharide-based Stationary Phases for Enantiomeric Resolution of Chiral Xanthone Derivatives". Paper presented in 23rd International Symposium on Pharmaceutical and Biomedical Analysis, João Pessoa, PB, Brazil,, 2011.
  118. Fernandes, Carla; Maria Elizabeth Tiritan; Quezia B. Cass; Miguel Fernandes; Madalena M. M. Pinto. "HPLC Enantioseparation and Chiral Recognition Mechanism of Novel Xanthone Derivatives on Macrocyclic Antibiotic Chiral Stationary Phases". Paper presented in HPLC 2011 - 36th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary, 2011.
  119. Alexandre Santos; Fernandes, Carla; Madalena M. M. Pinto; Maria Elizabeth Tiritan; Carlos Afonso. "Enantioresolution of Chiral Xanthone Derivatives by HPLC". Paper presented in IJUP11 – 4th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2011.
  120. Juliana Garcia; Fernandes, Carla; Madalena M. M. Pinto; Maria Elizabeth Tiritan; Carlos Afonso. "O-(Benzotriazol-1-yl)-N-N-N’-N’-tetramethyluronium tetrafluoroborate as an Efficient Coupling Reagent for the Synthesis of Chiral Xanthones". Paper presented in IJUP11 – 4th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2011.
  121. Inês Ramos; Fernandes, Carla; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto; Marlene Lúcio; Paula C.A.G. Pinto; M. Lúcia M.F.S. Saraiva; Salette Reis. "Anti-inflammatory Activities of Chiral Xanthones - Activity and inhibition of bee venom phospholipase A2 and ovine COX-1 and human recombinant COX-2". Paper presented in IJUP11 – 4th Meeting of Young Researchers of U. Porto, Porto, Portugal, 2011.
  122. Fernandes, Carla; Pedro Brandão; Maria Elizabeth Tiritan; Carlos Afonso; Quezia B. Cass; Madalena M. M. Pinto. "Efficient Methodology for Synthesis of Chiral Xanthone Derivatives in Enantiomerically Pure Form". Paper presented in 2nd National Meeting on Medicinal Chemistry, Coimbra, Portugal, 2010.
  123. Fernandes, Carla; Pedro Brandão; Maria Elizabeth Tiritan; Carlos Afonso; Quezia B. Cass; Madalena M. M. Pinto. "Application of Polysaccharide-based Stationary Phases in the Separation of Chiral Xanthone Derivatives". Paper presented in 2nd Portuguese Young Chemists Meeting, Aveiro, Portugal, 2010.
  124. Juliana Garcia; Fernandes, Carla; Madalena M. M. Pinto; Maria Elizabeth Tiritan; Carlos Afonso. "Chiral Xanthones with Potencial Antioxidant and Anti-inflammatory Activities: Synthesis and Structure Elucidation". Paper presented in IJUP10 – 3rd Meeting of Young Researchers of U. Porto, Porto, Portugal, 2010.
  125. Pedro Brandão; Fernandes, Carla; Maria Elizabeth Tiritan; Quezia B. Cass; Madalena M. M. Pinto. "HPLC Enantioseparation of Chiral Xanthone Derivatives on Polysaccharide-based Stationary Phases". Paper presented in IJUP10 – 3rd Meeting of Young Researchers of U. Porto, Porto, Portugal, 2010.
  126. Inês Ramos; D. Gaspar; J.L.F.C. Lima; Marlene Lúcio; Salette Reis; Fernandes, Carla; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Activity and inhibition of bee venom phospholipase A2 studied by fluorescent methodologies". Paper presented in IJUP10 – 3rd Meeting of Young Researchers of U. Porto, Porto, Portugal, 2010.
  127. Fernandes, Carla; Pedro Brandão; Maria Elizabeth Tiritan; Carlos Afonso; Quezia B. Cass; Madalena M. M. Pinto. "Direct HPLC enantioseparation of chiral xanthones on polysaccharide and macrocyclic antibiotic-based chiral stationary phases". Paper presented in 6º Encontro Nacional de Cromatografia, Funchal, Portugal, 2009.
  128. Maria Elizabeth Tiritan; Fernandes, Carla; Quezia B. Cass; Madalena M. M. Pinto. "Chiral Xanthone Derivatives: Synthesis, Structure Elucidation and HPLC Determination of the Enantiomeric Purity". Paper presented in 13th Brazilian Meeting on Organic Chemistry, São Pedro, SP-Brazil, 2009.
  129. Patrícia Rodrigues; Maria Elizabeth Tiritan; Fernandes, Carla; Madalena M. M. Pinto. "Coupling reaction of a carboxyxanthone with a chiral amino acid". Paper presented in III Jornadas de Ciências do ISCS-N “Ciência: a Causa das Coisas, Porto, Portugal, 2009.
  130. Ana Pinto; Inês Teixeira; Luís Leitão; Angelo Pozzi; José Bernardo Noronha-Matos; Fernandes, Carla; Laura Oliveira; Paulo Correia-de-Sá; Madalena M. M. Pinto. "Chiral Xanthone Derivatives: Synthesis, Structure Elucidation and Neuronal Activity". Paper presented in 2nd Meeting of Young Researchers of U. Porto, Porto, Portugal, 2009.
  131. Ana Pinto; Fernandes, Carla; Inês Teixeira; Maria Elizabeth Tiritan; Angelo Pozzi; José Bernardo Noronha-Matos; Luís Leitão; et al. "Chiral amino alcohol xanthone derivatives: synthesis, structural elucidation and biological activities". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, Portugal, 2008.
  132. Fernandes, Carla; Maria Elizabeth Tiritan; Quezia B. Cass; Madalena M. M. Pinto. "Synthesis and HPLC determination of the enantiomeric purity of valinol xanthone derivatives using macrocyclic antibiotic-based chiral stationary phases". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, Portugal, 2008.
  133. Maria Elizabeth Tiritan; Fernandes, Carla; Quezia B. Cass; Madalena M. M. Pinto. "Synthesis of L and D leucinol xanthone derivatives and HPLC determination of the enantiomeric purity by chiral stationary phase ristocetin A". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, Portugal, 2008.
  134. Inês Teixeira; Fernandes, Carla; Ana Pinto; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Synthesis of L and D leucinol xanthone derivatives and HPLC determination of the enantiomeric purity by chiral stationary phase ristocetin A". Paper presented in 1st National Meeting on Medicinal Chemistry, Porto, Portugal, 2008.
  135. Inês Teixeira; Madalena M. M. Pinto; Fernandes, Carla. "Synthesis, Structural Elucidation and Biological Activities of Chiral 1-Amino-2-Propanol Xanthone Derivatives". Paper presented in First Meeting of Young Researchers of U. Porto, Porto, Portugal, 2008.
  136. Ana Pinto; Fernandes, Carla; Madalena M.M. Pinto; Angelo Pozzi; José Bernardo Noronha-Matos; Laura Oliveira; Paulo Correia-de-Sá. "Chiral Alaninol Xanthone Derivatives: Synthesis, Structural Elucidation and Biological Activities". Paper presented in First Meeting of Young Researchers of U. Porto, Porto, Portugal, 2008.
  137. José Bernardo Noronha-Matos; Angelo Pozzi; Ana Pinto; Inês Teixeira; Emidio Fernandes; David Moreira; Fernandes, Carla; et al. "Conduction block in isolated rat sciatic nerve by chiral aminoalkanolic derivatives of xanthones". Paper presented in First Meeting of Young Researchers of U. Porto, Porto, Portugal, 2008.
  138. Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Chiral Amino Alcohol Xanthonic Derivatives". Paper presented in Medicinal Chemistry in the 21st Century, Lisbon, Portugal, 2006.
  139. Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Derivados Xantónicos Quirais: Síntese e Elucidação Estrutural". Paper presented in 6º Encontro Nacional de Química Orgânica, Braga, Portugal, 2005.
  140. Madalena M. M. Pinto; Carlos Afonso; Maria S.J. Nascimento; Maria J. Gonzaléz; Honorina Cidade; Maria Elizabeth Tiritan; Luís Vieira; et al. "Substâncias bioactivas de origem natural e de síntese: obtenção, caracterização estrutural, actividades biológicas e determinação de mecanismos de acção". Paper presented in Simpósio Os Farmacêuticos no Sistema de Saúde, Lisbon, Portugal, 2005.
  141. Fernandes, Carla; Branca Teixiera; Carla La-salette; Catarina Rodrigues; João Capela; Luísa Silva. "AINEs-Profármacos". Paper presented in I Jornadas Monográficas, FFUP, Porto, Portugal, 1998.
Journal article
  1. Flávia Barbosa; Joana Araújo; Virgínia M. F. Gonçalves; Andreia Palmeira; Andrea Cunha; Patrícia M. A. Silva; Carla Fernandes; et al. "Evaluation of Antitumor Activity of Xanthones Conjugated with Amino Acids". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25042121.
    10.3390/ijms25042121
  2. Ricardo Ribeiro; Lia Costa; Eugénia Pinto; Emília Sousa; Carla Fernandes. "Therapeutic Potential of Marine-Derived Cyclic Peptides as Antiparasitic Agents". Marine Drugs (2023): https://doi.org/10.3390/md21120609.
    10.3390/md21120609
  3. Salar Hafez Ghoran; Fatemeh Taktaz; Emília Sousa; Carla Fernandes; Anake Kijjoa. "Peptides from Marine-Derived Fungi: Chemistry and Biological Activities". Marine Drugs (2023): https://doi.org/10.3390/md21100510.
    10.3390/md21100510
  4. Lia Costa; Emília Sousa; Carla Fernandes. "Cyclic Peptides in Pipeline: What Future for These Great Molecules?". Pharmaceuticals (2023): https://doi.org/10.3390/ph16070996.
    10.3390/ph16070996
  5. Sara F. Vieira; Joana Araújo; Virgínia M. F. Gonçalves; Carla Fernandes; Madalena Pinto; Helena Ferreira; Nuno M. Neves; Maria Elizabeth Tiritan. "Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones Conjugated with Proteinogenic Amino Acids". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241210357.
    10.3390/ijms241210357
  6. Ana Sofia Almeida; Bárbara Silva; João Pedro Silva; José Augusto Pereira; Fernando Remião; Carla Fernandes. "Semi-Preparative Separation, Absolute Configuration, Stereochemical Stability and Effects on Human Neuronal Cells of MDPV Enantiomers". Molecules (2023): https://doi.org/10.3390/molecules28052121.
    10.3390/molecules28052121
  7. Ana Sofia Almeida; Bárbara Silva; Fernando Remião; Carla Fernandes. "Assessment of the Permeability of 3,4-Methylenedioxypyrovalerone (MDPV) across the Caco-2 Monolayer for Estimation of Intestinal Absorption and Enantioselectivity". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24032680.
    10.3390/ijms24032680
  8. Joko Tri Wibowo; Asep Bayu; Widya Dwi Aryati; Carla Fernandes; Arry Yanuar; Anake Kijjoa; Masteria Yunovilsa Putra. "Secondary Metabolites from Marine-Derived Bacteria with Antibiotic and Antibiofilm Activities against Drug-Resistant Pathogens". Marine Drugs (2023): https://doi.org/10.3390/md21010050.
    10.3390/md21010050
  9. Carla Fernandes; Ricardo Ribeiro; Madalena Pinto; Anake Kijjoa. "Absolute Stereochemistry Determination of Bioactive Marine-Derived Cyclopeptides by Liquid Chromatography Methods: An Update Review (2018–2022)". Molecules (2023): https://doi.org/10.3390/molecules28020615.
    10.3390/molecules28020615
  10. Sofia Almeida, A.; Cardoso, T.; Cravo, S.; Elizabeth Tiritan, M.; Remião, F.; Fernandes, C.. "Binding studies of synthetic cathinones to human serum albumin by high-performance affinity chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1227 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85165534359&partnerID=MN8TOARS.
    10.1016/j.jchromb.2023.123836
  11. Fernandes, Carla; Lima, Rita; Pinto, Madalena M.M.; Tiritan, Maria Elizabeth. "Chromatographic supports for enantioselective liquid chromatography: Evolution and innovative trends". Journal of Chromatography A 1684 (2022): 463555. http://dx.doi.org/10.1016/j.chroma.2022.463555.
    10.1016/j.chroma.2022.463555
  12. Rita Lima; Carla Fernandes; Madalena M. M. Pinto. "Molecular modifications, biological activities, and applications of chitosan and derivatives: A recent update". Chirality (2022): https://doi.org/10.1002/chir.23477.
    10.1002/chir.23477
  13. José X. Soares; Álvaro Santos; Carla Fernandes; Madalena M. M. Pinto. "Liquid Chromatography on the Different Methods for the Determination of Lipophilicity: An Essential Analytical Tool in Medicinal Chemistry". Chemosensors (2022): https://doi.org/10.3390/chemosensors10080340.
    10.3390/chemosensors10080340
  14. Ricardo Ribeiro; Eugénia Pinto; Carla Fernandes; Emília Sousa. "Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies". Marine Drugs 20 6 (2022): 397-397. https://doi.org/10.3390/md20060397.
    10.3390/md20060397
  15. Vedovello, Priscila; Costa, José Arnaldo Santana; Fernandes, Carla; Tiritan, Maria Elizabeth; Paranhos, Caio Marcio. "Evaluation of chiral separation by Pirkle-type chiral selector based mixed matrix membranes". Separation and Purification Technology 289 (2022): 120722. http://dx.doi.org/10.1016/j.seppur.2022.120722.
    10.1016/j.seppur.2022.120722
  16. Barbara Silva; Joana S. Rodrigues; Ana Sofia da Costa Almeida; Ana Rita Couto Machado Lima; Carla Fernandes; Guedes de Pinho P.; Joana P Miranda; Fernando Remiao. "Enantioselectivity of Pentedrone and Methylone on Metabolic Profiling in 2D and 3D Human Hepatocyte-like Cells". Pharmaceuticals (2022): https://www.mdpi.com/1424-8247/15/3/368.
    10.3390/ph15030368
  17. Ana Sofia da Costa Almeida; Barbara Silva; Guedes de Pinho P.; Fernando Remiao; Carla Fernandes. "Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods". Molecules (2022): https://www.mdpi.com/1420-3049/27/7/2057.
    10.3390/molecules27072057
  18. "Chiral polymeric membranes: Recent applications and trends". Separation and Purification Technology 280 (2022): 119800-119800. http://dx.doi.org/10.1016/j.seppur.2021.119800.
    10.1016/j.seppur.2021.119800
  19. Gonçalves, Layane; Fernandes, Carla; Tiritan, Maria Elizabeth; Cravo, Sara. Corresponding author: Tiritan, Maria Elizabeth. "Development and Evaluation of Pirkle-type chiral stationary phase for flash chromatography". Journal of Chromatography A (2022):
    Submitted
  20. Gonçalves, L.; Cravo, S.; Fernandes, C.; Tiritan, M.E.. "Development and evaluation of Pirkle-type chiral stationary phase for flash chromatography". Journal of Chromatography A 1675 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85130606131&partnerID=MN8TOARS.
    10.1016/j.chroma.2022.463156
  21. Fernando Durães; Sara Cravo; Joana Freitas-Silva; Nikoletta Szemerédi; Paulo Martins-da-Costa; Eugénia Pinto; Maria Elizabeth Tiritan; et al. "Enantioselectivity of Chiral Derivatives of Xanthones in Virulence Effects of Resistant Bacteria". Pharmaceuticals 14 11 (2021): 1141-1141. https://doi.org/10.3390/ph14111141.
    10.3390/ph14111141
  22. Tony Cardoso; Ana Sofia Almeida; Fernando Remião; Carla Fernandes. "Enantioresolution and Binding Affinity Studies on Human Serum Albumin: Recent Applications and Trends". Chemosensors 9 11 (2021): 304-304. https://doi.org/10.3390/chemosensors9110304.
    10.3390/chemosensors9110304
  23. Carla Fernandes; Joana Teixeira; Madalena M. M. Pinto; Maria Elizabeth Tiritan. "Strategies for Preparation of Chiral Stationary Phases: Progress on Coating and Immobilization Methods". Molecules (2021): https://doi.org/10.3390/molecules26185477.
    10.3390/molecules26185477
  24. Maria Miguel Coelho; Carla Fernandes; Fernando Remião; Maria Elizabeth Tiritan. "Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods". Molecules 26 11 (2021): 3113-3113. https://doi.org/10.3390/molecules26113113.
    10.3390/molecules26113113
  25. Silva, Bárbara; Palmeira, Andreia; Silva, Renata; Fernandes, Carla; Guedes de Pinho, Paula; Remião, Fernando. "S-(+)-Pentedrone and R-(+)-methylone as the most oxidative and cytotoxic enantiomers to dopaminergic SH-SY5Y cells: Role of MRP1 and P-gp in cathinones enantioselectivity". Toxicology and Applied Pharmacology 416 (2021): 115442. http://dx.doi.org/10.1016/j.taap.2021.115442.
    10.1016/j.taap.2021.115442
  26. Madalena M. M. Pinto; Andreia Palmeira; Carla Fernandes; Diana I. S. P. Resende; Emília Sousa; Honorina Cidade; Maria Elizabeth Tiritan; Marta Correia-da-Silva; Sara Cravo. "From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones". Molecules 26 2 (2021): 431-431. https://doi.org/10.3390/molecules26020431.
    10.3390/molecules26020431
  27. Ye' Zaw Phyo; Joana Teixeira; Ricardo Gonçalves; Andreia Palmeira; Maria Elizabeth Tiritan; Hassan Bousbaa; Madalena M.M. Pinto; Carla Fernandes; Anake Kijjoa. "Chiral derivatives of xanthones and benzophenones: Synthesis, enantioseparation, molecular docking, and tumor cell growth inhibition studies". Chirality (2021): https://doi.org/10.1002/chir.23297.
    10.1002/chir.23297
  28. Fernandes, Carla; Afonso, Carlos; Cidade, Honorina; Maria E. Tiritan; E. Sousa; Correia-da-Silva, Marta. "IUC4: Integração de Unidades Curriculares Básicas e Profissionalizantes". Cadernos de Inovação Pedagógica 1 (2021): 41-49.
    Published
  29. Maria L. Carraro; Sandra Marques; Ana Sofia Silva; Bruno Freitas; Patrícia M. A. Silva; Joel Pedrosa; Paolo De Marco; et al. "Synthesis of New Chiral Derivatives of Xanthones with Enantioselective Effect on Tumor Cell Growth and DNA Crosslinking". ChemistrySelect 5 33 (2020): 10285-10291. https://doi.org/10.1002/slct.202002588.
    10.1002/slct.202002588
  30. Madalena M.M. Pinto; Carla Fernandes; Maria E. Tiritan. "Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View". Molecules 25 8 (2020): 1931-1931. https://doi.org/10.3390/molecules25081931.
    10.3390/molecules25081931
  31. Maria Elizabeth Tiritan; Madalena Pinto; Carla Fernandes. "Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition". Molecules 25 7 (2020): 1713-1713. https://doi.org/10.3390/molecules25071713.
    10.3390/molecules25071713
  32. Ye' Zaw Phyo; Joana Teixeira; Maria Elizabeth Tiritan; Sara Cravo; Andreia Palmeira; Luís Gales; Artur M.S. Silva; et al. "New chiral stationary phases for liquid chromatography based on small molecules: Development, enantioresolution evaluation and chiral recognition mechanisms". Chirality 32 1 (2020): 81-97. https://doi.org/10.1002/chir.23142.
    10.1002/chir.23142
  33. Silva, B.; Silva, R.; Fernandes, C.; Guedes de Pinho, P.; Remião, F.. "Enantioselectivity on the absorption of methylone and pentedrone using Caco-2 cell line: Development and validation of an UHPLC method for cathinones quantification". Toxicology and Applied Pharmacology 395 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85082722054&partnerID=MN8TOARS.
    10.1016/j.taap.2020.114970
  34. Joana Teixeira; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Carla Fernandes. "Chiral Stationary Phases for Liquid Chromatography: Recent Developments". Molecules (2019): https://doi.org/10.3390/molecules24050865.
    10.3390/molecules24050865
  35. Carla Fernandes; Maria Leticia Carraro; João Ribeiro; Joana Araújo; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Synthetic Chiral Derivatives of Xanthones: Biological Activities and Enantioselectivity Studies". Molecules (2019): https://www.mdpi.com/1420-3049/24/4/791.
    10.3390/molecules24040791
  36. Joana Araújo; Carla Fernandes; Madalena M. M. Pinto; Maria Elizabeth Tiritan. "Chiral Derivatives of Xanthones with Antimicrobial Activity". Molecules (2019): http://www.mdpi.com/1420-3049/24/2/314.
    10.3390/molecules24020314
  37. João Ribeiro; Cláudia Veloso; Carla Fernandes; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Carboxyxanthones: Bioactive Agents and Molecular Scaffold for Synthesis of Analogues and Derivatives". Molecules (2019): http://www.mdpi.com/1420-3049/24/1/180.
    10.3390/molecules24010180
  38. Do Carmo, J.P.; Phyo, Y.Z.; Palmeira, A.; Tiritan, M.E.; Afonso, C.; Kijjoa, A.; M Pinto, M.M.; Fernandes, C.. "Enantioseparation, recognition mechanisms and binding of xanthones on human serum albumin by liquid chromatography". Bioanalysis 11 13 (2019): 1255-1274. http://www.scopus.com/inward/record.url?eid=2-s2.0-85071533708&partnerID=MN8TOARS.
    10.4155/bio-2019-0074
  39. Coelho, M.M.; Lado Ribeiro, A.R.; Sousa, J.C.G.; Ribeiro, C.; Fernandes, C.; Silva, A.M.T.; Tiritan, M.E.. "Dual enantioselective LC–MS/MS method to analyse chiral drugs in surface water: Monitoring in Douro River estuary". Journal of Pharmaceutical and Biomedical Analysis 170 (2019): 89-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063201661&partnerID=MN8TOARS.
    10.1016/j.jpba.2019.03.032
  40. Maria E. Tiritan; Carla Fernandes; Alexandra S. Maia; Madalena Pinto; Quezia B. Cass. "Enantiomeric ratios: Why so many notations?". Journal of Chromatography A (2018): https://doi.org/10.1016/j.chroma.2018.07.039.
    10.1016/j.chroma.2018.07.039
  41. Fernandes, C.; Phyo, Y.Z.; Silva, A.S.; Tiritan, M.E.; Kijjoa, A.; Pinto, M.M.M.. "Chiral Stationary Phases Based on Small Molecules: An Update of the Last 17 Years". Separation and Purification Reviews 47 2 (2018): 89-123. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042070693&partnerID=MN8TOARS.
    10.1080/15422119.2017.1326939
  42. Santos, Á.; Soares, J.X.; Cravo, S.; Tiritan, M.E.; Reis, S.; Afonso, C.; Fernandes, C.; Pinto, M.M.M.. "Lipophilicity assessement in drug discovery: Experimental and theoretical methods applied to xanthone derivatives". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1072 (2018): 182-192. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034659767&partnerID=MN8TOARS.
    10.1016/j.jchromb.2017.10.018
  43. Phyo, Y.Z.; Cravo, S.; Palmeira, A.; Tiritan, M.E.; Kijjoa, A.; Pinto, M.M.M.; Fernandes, C.. "Enantiomeric resolution and docking studies of chiral xanthonic derivatives on chirobiotic columns". Molecules 23 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040530715&partnerID=MN8TOARS.
    10.3390/molecules23010142
  44. Phyo, Y.; Ribeiro, J.; Fernandes, C.; Kijjoa, A.; Pinto, M.M.M.. "Marine natural peptides: Determination of absolute configuration using liquid chromatography methods and evaluation of bioactivities". Molecules 23 2 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041609875&partnerID=MN8TOARS.
    10.3390/molecules23020306
  45. Silva, B.; Fernandes, C.; de Pinho, P.G.; Remião, F.. "Chiral resolution and enantioselectivity of synthetic cathinones: A brief review". Journal of Analytical Toxicology 42 1 (2018): 17-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042560674&partnerID=MN8TOARS.
    10.1093/jat/bkx074
  46. Lopes, A.; Martins, E.; Silva, R.; Pinto, M.M.M.; Remião, F.; Sousa, E.; Fernandes, C.. "Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies". Molecules 23 3 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85044325048&partnerID=MN8TOARS.
    10.3390/molecules23030626
  47. Silva, B.; Pereira, J.A.; Cravo, S.; Araújo, A.M.; Fernandes, C.; Pinto, M.M.M.; de Pinho, P.G.; Remião, F.. "Multi-milligram resolution and determination of absolute configuration of pentedrone and methylone enantiomers". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1100-1101 (2018): 158-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054789260&partnerID=MN8TOARS.
    10.1016/j.jchromb.2018.10.002
  48. Carla Fernandes; Maria Elizabeth Tiritan; Sara Cravo; Ye’ Zaw Phyo; Anake Kijjoa; Artur M.S. Silva; Quezia B. Cass; Madalena M.M. Pinto. "New chiral stationary phases based on xanthone derivatives for liquid chromatography". Chirality 29 8 (2017): 430-442. https://doi.org/10.1002%2Fchir.22706.
    10.1002/chir.22706
  49. Fernandes, C.; Palmeira, A.; Ramos, I.I.; Carneiro, C.; Afonso, C.; Tiritan, M.E.; Cidade, H.; et al. "Chiral derivatives of xanthones: Investigation of the effect of enantioselectivity on inhibition of cyclooxygenases (COX-1 and COX-2) and binding interaction with human serum albumin". Pharmaceuticals 10 2 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85020709871&partnerID=MN8TOARS.
    10.3390/ph10020050
  50. Fernandes, C.; Tiritan, M.E.; Pinto, M.M.M.. "Chiral separation in preparative scale: A brief overview of membranes as tools for enantiomeric separation". Symmetry 9 10 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85031404913&partnerID=MN8TOARS.
    10.3390/sym9100206
  51. Ribeiro, J.; Tiritan, M.E.; Pinto, M.M.M.; Fernandes, C.. "Chiral stationary phases for liquid chromatography based on chitin- and chitosan-derived marine polysaccharides". Symmetry 9 9 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85029445338&partnerID=MN8TOARS.
    10.3390/sym9090190
  52. Carraro, M.L.; Palmeira, A.; Tiritan, M.E.; Fernandes, C.; Pinto, M.M.M.. "Resolution, determination of enantiomeric purity and chiral recognition mechanism of new xanthone derivatives on (S,S)-whelk-O1 stationary phase". Chirality 29 6 (2017): 247-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018831141&partnerID=MN8TOARS.
    10.1002/chir.22703
  53. Zin, W.W.M.; Buttachon, S.; Dethoup, T.; Fernandes, C.; Cravo, S.; Pinto, M.M.M.; Gales, L.; et al. "New cyclotetrapeptides and a new diketopiperzine derivative from the marine sponge-associated fungus Neosartorya glabra KUFA 0702". Marine Drugs 14 7 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84979518314&partnerID=MN8TOARS.
    10.3390/md14070136
  54. Gomes, A.S.; Brandão, P.; Fernandes, C.S.G.; Da Silva, M.R.P.C.; De Sousa, M.E.D.S.P.; De Magalhães Pinto, M.M.. "Drug-like properties and ADME of xanthone derivatives: The antechamber of clinical trials". Current Medicinal Chemistry 23 32 (2016): 3654-3686. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995948323&partnerID=MN8TOARS.
    10.2174/0929867323666160425113058
  55. Silva, B.; Fernandes, C.; Tiritan, M.E.; Pinto, M.M.M.; Valente, M.J.; Carvalho, M.; de Pinho, P.G.; Remião, F.. "Chiral enantioresolution of cathinone derivatives present in “legal highs”, and enantioselectivity evaluation on cytotoxicity of 3,4-methylenedioxypyrovalerone (MDPV)". Forensic Toxicology 34 2 (2016): 372-385. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974807559&partnerID=MN8TOARS.
    10.1007/s11419-016-0324-y
  56. Prompanya, C.; Fernandes, C.; Cravo, S.; Pinto, M.M.M.; Dethoup, T.; Silva, A.M.S.; Kijjoa, A.. "A new cyclic hexapeptide and a new isocoumarin derivative from the marine sponge-associated fungus Aspergillus similanensis KUFA 0013". Marine Drugs 13 3 (2015): 1432-1450. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925846750&partnerID=MN8TOARS.
    10.3390/md13031432
  57. Fernandes, Carla; Maria Elizabeth Tiritan; Madalena Maria de Magalhães Pinto. "Chiral derivatives of xanthones: applications in Medicinal Chemistry and a new approach in Liquid Chromatography". Scientia Chromatographica 7 3 (2015): 1-14.
  58. Fernandes, C.; Masawang, K.; Tiritan, M.E.; Sousa, E.; De Lima, V.; Afonso, C.; Bousbaa, H.; et al. "New chiral derivatives of xanthones: Synthesis and investigation of enantioselectivity as inhibitors of growth of human tumor cell lines". Bioorganic and Medicinal Chemistry 22 3 (2014): 1049-1062. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892824290&partnerID=MN8TOARS.
    10.1016/j.bmc.2013.12.042
  59. Fernandes, Carla; Madalena Maria de Magalhães Pinto ; Maria Elizabeth Tiritan. "Enantioresolution of chiral derivatives of xanthones on different types of liquid chromatography stationary phases: a comparative study". Current Chromatography 1 2 (2014): 139-150.
  60. Fernandes, C.; Palmeira, A.; Santos, A.; Tiritan, M.E.; Afonso, C.; Pinto, M.M.. "Enantioresolution of chiral derivatives of xanthones on (S,S)-Whelk-O1 and l -phenylglycine stationary phases and chiral recognition mechanism by docking approach for (S,S)-Whelk-O1". Chirality 25 2 (2013): 89-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872834041&partnerID=MN8TOARS.
    10.1002/chir.22112
  61. Fernandes, C.; Tiritan, M.E.; Pinto, M.. "Small molecules as chromatographic tools for HPLC enantiomeric resolution: Pirkle-type chiral stationary phases evolution". Chromatographia 76 15-16 (2013): 871-897. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881142318&partnerID=MN8TOARS.
    10.1007/s10337-013-2469-8
  62. Fernandes, C.; Brandão, P.; Santos, A.; Tiritan, M.E.; Afonso, C.; Cass, Q.B.; Pinto, M.M.. "Resolution and determination of enantiomeric purity of new chiral derivatives of xanthones using polysaccharide-based stationary phases". Journal of Chromatography A 1269 (2012): 143-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870339987&partnerID=MN8TOARS.
    10.1016/j.chroma.2012.07.058
  63. Fernandes, C.; Tiritan, M.E.; Cass, Q.; Kairys, V.; Fernandes, M.X.; Pinto, M.. "Enantioseparation and chiral recognition mechanism of new chiral derivatives of xanthones on macrocyclic antibiotic stationary phases". Journal of Chromatography A 1241 (2012): 60-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860674472&partnerID=MN8TOARS.
    10.1016/j.chroma.2012.04.011
  64. Fernandes, C.; Oliveira, L.; Tiritan, M.E.; Leitao, L.; Pozzi, A.; Noronha-Matos, J.B.; Correia-De-Sá, P.; Pinto, M.M.. "Synthesis of new chiral xanthone derivatives acting as nerve conduction blockers in the rat sciatic nerve". European Journal of Medicinal Chemistry 55 (2012): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865764202&partnerID=MN8TOARS.
    10.1016/j.ejmech.2012.06.049
Newsletter article
  1. Fernandes, Carla; Andreia Palmeira; Alexandre Santos; Maria Elizabeth Tiritan; Carlos Afonso; Madalena M. M. Pinto. "Chiral HPLC separation of chiral derivatives of xanthones using the (S,S)-Whelk-O® 1 chiral stationary phase", Application Note: Chiral, by Regis Technologies, Inc., LCGC North America, 2015

Intellectual property

Patent
  1. Fernandes, Carla; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Quezia B. Cass. 2011. "Fases Estacionárias Quirais baseadas em Derivados Xantónicos". Portugal.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/12 Semi-preparative enantioseparation of cathinone derivatives on amylose-derived LC columns and binding studies to human serum albumin by HPALC 12º Encontro Nacional de Cromatografia & XIV WARPA
(Portugal)
2022/11 Semi-preparative separation and racemization study of MDPV enantiomers by liquid chromatography and absorption study on Caco-2 model XXVI Encontro Luso-Galego de Química
(Spain)
2022/11 Polysaccharides from marine sources: synthesis of derivatives and tumor cell growth inhibition XXVI Encontro Luso-Galego de Química
(Spain)
2022/05 Synthesis of marine-derived xanthone analogues and in silico studies on inhibition of cyclooxygenases enzymes IJUP2022 - 15th Meeting of Young Researches of University of Porto
(Portugal)
2022/05 Chitosan conjugates: synthesis and antitumor activity IJUP2022 - 15th Meeting of Young Researches of University of Porto
(Portugal)
2022/05 Anti-inflammatory activity evaluation of synthetic carboxyxanthones and intermediates IJUP2022 - 15th Meeting of Young Researches of University of Porto
(Portugal)
2022/01 A view of Medicinal Chemistry through the looking glass: enantioselectivity studies with chiral derivatives of xanthones 14th National Organic Chemistry Meeting (14ENQO) - 7th National Medicinal Chemistry Meeting (7ENQT)
(Portugal)
2021/11/04 Aulas laboratoriais em pandemia – adaptação a novos modelos nas UC do LQOF Congresso Pedagógico FFUP
(Portugal)
2021/11/04 FUVET: uma colaboração entre unidades orgânicas para a aquisição de competências sobre fármacos de uso veterinário Congresso Pedagógico FFUP
(Portugal)
2021/11/04 Interação biunívoca entre unidades curriculares básicas e profissionalizantes – Uma experiência do LQOF Congresso Pedagógico FFUP
(Portugal)
2021/05/26 Toxicokinetic/toxicodynamic studies of pentedrone and methylone: enantioselective approach 1st Spring Virtual Meeting on Medicinal Chemistry
2021/05/05 Amino acid derivatives of chrysin: synthesis and enantioselectivity study as inhibitors of growth of tumor cell lines 14th Meeting of Young Researches of University of Porto
(Portugal)
2021/05/05 Xanthone derivatives: synthesis and structure elucidation of two isomers 14th Meeting of Young Researches of University of Porto
(Portugal)
2021/05/05 Synthesis and structure elucidation of new xanthone derived atropisomers for biological activity evaluation 14th Meeting of Young Researches of University of Porto, Portugal
(Portugal)
2021/05/05 Synthesis and structure elucidation of a series of chitosan conjugates with potential as inhibitors of growth tumor cell lines 14th Meeting of Young Researches of University of Porto, Portugal
(Portugal)
2021/02/17 Metabolism of pentedrone and methylone in HLCs: na enantioselectivity approach SPF Meeting 2021
(Portugal)
2021/02 Metabolism of pentedrone and methylone in HLCs: na enantioselectivity approach SPF Meeting 2021
Faculty of Pharmacy of University of Lisbon
2020/11/24 Chitosan conjugates with potential as antitumor agents and chiral stationary phases: synthesis though a Schiff base intermediate Simpósio de Investigação da FFUP (SIFFUP)
2020/11/24 Syntheis of chiral amino acid derivatives of chrysin as potential anti-tumor agents Simpósio de Investigação da FFUP (SIFFUP)
2020/11/24 Synthesis and structure elucidation of new atropisomers for biological activity evaluation Simpósio de Investigação da FFUP (SIFFUP)
2020/11/24 Synthesis and structure elucidation of two isomeric carboxyxanthone derivatives Simpósio de Investigação da FFUP (SIFFUP)
2020/11 Chitosan conjugates with potential as antitumor agents and chiral stationary phases: synthesis though a Schiff base intermediate Simpósio de Investigação da FFUP (SIFFUP)
Faculty of Pharmacy of University of Porto
2020/11 Syntheis of chiral amino acid derivatives of chrysin as potential anti-tumor agents Simpósio de Investigação da FFUP (SIFFUP)
Faculty of Pharmacy of University of Porto
2020/11 Synthesis and structure elucidation of two isomeric carboxyxanthone derivatives Simpósio de Investigação da FFUP (SIFFUP)
Faculty of Pharmacy of University of Porto
2020/11 Synthesis and structure elucidation of new atropisomers for biological activity evaluation Simpósio de Investigação da FFUP (SIFFUP)
Faculty of Pharmacy of University of Porto
2020/09/26 Derivados xantónicos quirais: aplicações em Química Medicinal e em Cromatografia Líquida 3.ª rRACS 2020
2020/09/17 Quantification of chiral drugs in environmental in Douro river estuary by LC-MS/MS Blue Think Conference: Share Science, Spread Knowledge
CIIMAR
2020/09 Derivados xantónicos quirais: aplicações em Química Medicinal e em Cromatografia Líquida 3.ª rRACS 2020
2020/02/12 Enantioselective synthesis of xanthones derivatives with potential biological activity 13th Meeting of Young Researches of University of Porto, Portugal
(Portugal)
2020/02/12 Stationary phases for liquid chromatography comprising two chiral moieties: synthesis, enantioresolution performance and recognition mechanisms 13th Meeting of Young Researches of University of Porto
(Portugal)
2020/02 Studies of intestinal permeability of cathinones using Caco-2 cell monolayer: an enantioselectivity approach SPF Meeting 2020
(Coimbra, Portugal)
2020/02 IUC4: Integração de Unidades Curriculares Básicas e Profissionalizantes Workshop Anual de Inovação e Partilha Pedagógica da Universidade do Porto
(Portugal)
2019/11/26 New Stationary Phases for Liquid Chromatography based on Chiral Derivatives of Xanthones: Development, Enantioresolution Evaluation and Recognition Mechanisms SIFFUP – Simpósio Investigação Faculdade de Farmácia da Universidade do Porto
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2019/11/26 Derivados xantónicos carboxilados: síntese e elucidação estrutural SIFFUP – Simpósio Investigação Faculdade de Farmácia da Universidade do Porto
(Porto, Portugal)
2019/11/26 New enantiomeric pure chiral derivatives of 4’-methylchrysoeriol with promising antitumor activity SIFFUP – Simpósio Investigação Faculdade de Farmácia da Universidade do Porto
(Porto, Portugal)
2019/05/06 Enantioselectivity effects of synthetic cathinones in dopaminergic SH-SY5Y cells 1st Annual Meeting of the PhD Program in Experimental and Clinical Pharmacology and Toxicology
(Porto, Portugal)
2019/02 Pentedrone and methylone enantioselectivity in differentiated SH-SY5Y cells Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2018/11 Estratégias pedagógicas no ensino da química orgânica e farmacêutica em ambiente universitário VII Encontro da Divisão de Ensino e Divulgação da Química
(Portugal)
2018/02 HPLC enantioresolution of pentedrone and in vitro cytotoxicity studies Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
2017/01 A importância da quiralidade no desenvolvimento de novos fármacos 2ª Escola de Inverno de Farmácia
(Porto, Portugal)
2016/12 Chiral Derivatives of Xanthones: Resolution and Determination of Enantiomeric Purity on Different Types of Liquid Chromatography Stationary Phases 2nd Caparica Christmas Conference on Sample Treatment
(Portugal)
2016/07 Evaluation of cytotoxicity of both enantiomers of 3,4-methylenedioxypyrovalerone (MDPV) Encontro Anual do Departamento de Ciências Biológicas da Faculdade de Farmácia da Universidade do Porto
(Portugal)
2016/02 Enantioresolution and cytotocixity evaluation of the enantiomersof 3,4-methylenodioxipirovalerone (MDPV), I Congresso da Associação Portuguesa de Ciências Forenses e IV Congresso sobre o Abuso e Negligência de Crianças
(Porto, Portugal)
2015/02 VIII Jornadas monográficas de química farmacêutica – uma prática pedagógica em mudança Workshop Anual de Inovação e Partilha Pedagógica da Universidade do Porto
(Portugal)
2012/10 Comparative study of the resolution of chiral derivatives of xanthones on different types of HPLC stationary phases 1st Luso-Brazilian Symposium on Science
(Vassouras, Brazil)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/02 - Current Síntese de análogos de péptidos de origem marinha com potencial atividade antimicrobiana
Supervisor
 Project I (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2023/02 - Current Preparação de derivados quirais com potencial atividade antitumoral
Supervisor
 Project I (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/11 - Current Development of new chiral stationary phases for liquid chromatography based on xanthone and polysaccharide derivatives by a rational approach
Supervisor
 PhD in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/09 - Current Synthesis of new chiral derivatives of xanthones for enantioselective studies on antimicrobial activity
Supervisor
 Master in Medicinal Chemistry (Master)
Universidade de Coimbra, Portugal
2022/01 - Current Síntese de análogos de compostos de origem marinha com potencial atividade antimicrobiana
Supervisor
 Project I (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/01 - Current Marine cyclic peptides and analogues as promising antimicrobial agents: synthesis and structural characterization
Supervisor
 Master in Pharmaceutical Sciences (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/01 - Current Bioactive Compounds from Marine-Derived Fungus
Co-supervisor
 Master in Pharmaceutical Sciences (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/01 - Current Desenvolvimento de um modelo inovador para avaliação da bioacumulação no ecossistema marinho
Co-supervisor
 Master in Pharmaceutical Sciences (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - Current Synthesis of new chiral small molecules as anti-tumor agents
Supervisor
 Project II (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - Current Synthesis of biomimetic compounds for biological activity evaluation
Supervisor
 Project II (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - Current Síntese de derivados xantónicos quirais com potencial atividade antitumoral e anti-inflamatória
Co-supervisor
 Project I (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/01/01 - Current Synthesis and Evaluation of Antimicrobial Activity of Marine-derived Peptides and Analogues
Supervisor
 Doctoral Program in Marine Biotechnology and Aquaculture (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2020/01/01 - Current Development of new chiral stationary phases for liquid chromatography based on xanthone and polysaccharide derivatives: an integrative strategy
Supervisor
 Doctoral Program in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/01/01 - Current Enantioselective studies of promethazine and its metabolites: chemical and toxicology approaches
Co-supervisor of Maria Miguel Sampaio Salazar Coelho
 Doctoral Program in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/01 - Current Semi-preparative enantioseparation of synthetic cathinones by liquid chromatography and enantiselectivity studies in citotoxicity
Supervisor
 Masters in Analytical, Clinical and Forensic Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Current Carboxyxanthones and Atropisomers: synthesis and evaluation of anti-inflammatory activity
Supervisor of João Eduardo Ferreira Handel de Oliveira
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09 - 2021/09/20 Enantioselectivity of pentedrone and methylone: enantioresolution by liquid chromatography and in vitro toxicokinetic/toxicodynamic studies
Co-supervisor of Bárbara Sofia Poléri da Silva
 Doctoral Program in Experimental and Clinical Pharmacology and Toxicology (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2020/02 - 2021 Synthesis of carboxylated small molecules
Supervisor
 Project II (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - 2021 Synthesis of a marine-derived analogue with potential anti-inflammatory activity and in silico studies on inhibition of cyclooxygenase enzymes
Supervisor
 Project/Internship of Bachelor’s in Biochemistry (Scientific initiation)
Universidade do Porto Faculdade de Ciências, Portugal
2019 - 2021 Synthesis of New Polymeric Materials based on Chitosan with Potential Anti-Tumor Activity
Supervisor of Rita Alexandra Ferreira Alves de Lima
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2021 Development and evaluation of a Pirkle-type chiral stationary phase for flash chromatography
Supervisor of Layane Andrade Miranda Gonçalves
Masters in Biology and Water Quality Management (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2019 - 2020 Synthesis and structure elucidation of chiral amino acid derivatives of chrysin as potential anti-tumor agents
Supervisor of Ana Sofia Almeida
Project/Internship of Bachelors in Biochemistry (Scientific initiation)
Universidade do Porto Faculdade de Ciências, Portugal
2018 - 2020 Molecular recognition mechanisms and binding affinity of synthetic cathinones to human serum albumin by biocromatography
Supervisor of Tony Gomes Cardoso
Masters in Analytical, Clinical and Forensic Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2019/10/11 Synthesis of New Chiral Derivatives of Xanthone with Potential Biological Activity
Co-supervisor of Joana Margarida Soares Araújo
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2019/09 Synthesis of enantiomerically pure atropisomers
Supervisor
 Project/Internship of Bachelor’s in Biochemistry (Scientific initiation)
Universidade do Porto Faculdade de Ciências, Portugal
2017 - 2019/07/19 Development of new columns for liquid chromatography based on xanthone derivatives
Supervisor of Joana Filipa Barbosa Teixeira
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09 - 2019/07/12 Chiral Stationary Phases for Liquid Chromatography.: Development, Enantioseparation and Molecular Recognition Mechanism Studies
Supervisor of Ye’ Zaw Phyo
 Doctoral Program in Biomedical Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2019/07 Development and evaluation of chiral stationary phases for liquid chromatography
Supervisor of Bárbara Raquel Gomes Polónia
 Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2018/11/19 Monitoring of several chiral drugs in Douro River estuary by LC-MS/MS
Co-supervisor of Maria Miguel Sampaio Salazar Coelho
Masters in Analytical, Clinical and Forensic Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2018/11/09 Enantioresolution, chiral recognition mechanisms and binding of xanthone derivatives on immobilized human serum albumin by liquid chromatography
Supervisor of João Pedro Soares Pereira do Carmo
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/02 - 2018/07 Synthesis and evaluation of new chiral stationary phases based on xanthone derivatives
Supervisor of Krystyna Maslowska
 Project II (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2017/10/27 Development of new chiral stationary phases for liquid chromatography based on marine polymers
Supervisor of João Luís Pinto Ribeiro
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2017/10/23 Synthesis of new carboxylic chiral derivatives of xanthones inspired on marine xanthones
Co-supervisor
 Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/09 - 2017/09 Synthesis and purification of organic compounds
Supervisor
 Students Exchange Programme from International Pharmaceutical Students Federation (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2017/06 Carboxyxanthones: interesting building blocks for chiral derivatives and as bioactive agents
Supervisor of Patrícia Lima Barbosa
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2017/06 Synthesis of carboxylated xanthone derivatives with potential anti-inflammatory activity
Supervisor of Catarina Silva Crespo Amoêdo Leite
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2016/11/22 Chiral small molecules as P-gP modulators: synthesis and enantioselectivity studies
Supervisor of Ana Catarina Barros Lopes
Masters in Analytical, Clinical and Forensic Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2016/11/05 Separação enantiomérica de derivados catinónicos em drogas de abuso por HPLC quiral. Estudo da citotoxicidade dos enantiómeros da 3,4-metilenodioxipirovalerona (MDPV)
Co-supervisor of Bárbara Sofia Poléri da Silva
Masters in Forensic Sciences (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2016/07/29 Chiral derivatives of xanthones: synthesis, enantiomeric purity and effect on human tumor cell lines
Supervisor of Maria Leticia Carraro
Masters in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2016/07 Synthesis of new chiral derivatives of xanthones in enantiomerically pure form as promising antitumor agents
Supervisor of Bruno Miguel Ribeiro Freitas
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015/07 Development and evaluation of stationary phases for HPLC based in chiral xanthone derivatives
Supervisor of Ana Sofia Machado da Silva
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015/07 Lipophilicity determination of chiral derivatives of xanthones: comparison of methods
Supervisor of Álvaro José Dias dos Santos
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015/07 Synthesis and structure elucidation of carboxyxanthone derivatives
Supervisor of Claúdia Azevedo Veloso
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2012 - 2013/07 Synthesis and structure elucidation of enantiomeric pure chiral derivatives of xanthones
Co-supervisor of Diana Rute Martins Torres
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2012 - 2013/07 Development of chiral xanthonic stationary phases for HPLC
Co-supervisor of Ana Rita Rolim Farinha Marques
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2012 - 2013/07 Synthesis of Carboxyxanthonic Derivatives with Potential Anti-inflammatory activity
Co-supervisor of Sara Eunice Agostinho Monteiro
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012/09 Chiral xanthones: synthesis and docking studies with molecular targets associated with the anti-inflammatory process
Co-supervisor of Carlos Manuel Teixeira Carneiro
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2011/09 Studies of enantioresolution and mechanisms of chiral molecular recognition
Co-supervisor of Alexandre Lima Santos
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2011/09 Chiral xanthone derivatives: Synthesis, physicochemical properties and anti-inflammatory activity determination
Co-supervisor of Inês Isabel Barros Moreira Ramos
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2010/07 Determination of the Enantiomeric Purity of Chiral Xanthone Derivatives by High Performance Liquid Chromatography using Polysaccharide-based Chiral Stationary Phases
Co-supervisor
 Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2010/02 New chiral xanthone derivatives with potencial anti-inflamatory and antioxidant activity: synthesis and structure elucidation
Co-supervisor
 Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2009/09 - 2009/12 Synthesis of Carboxyxanthone Derivatives as Building Blocks for Enantiomeric Pure Compounds
Co-supervisor of Jana Heczková
 Project II (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2008/07 New Chiral Xanthonic Derivatives with Potential Antiepileptic Activity
Co-supervisor of Ana Rita Rodrigues Pinto
Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2008/07 Synthesis and structural elucidation of a xanthone derivative as a building block for new chiral compounds
Co-supervisor
 Project I of Masters in Pharmaceutical Sciences (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/11/06 - 2021/11/09 Jornadas Pedagógico-Científicas Madalena Pinto 21 (2021/11/06 - 2021/11/09) Universidade do Porto Faculdade de Farmácia, Portugal
2021/07/19 - 2021/07/23 Course From Organic Chemistry to Drugs: theory and laboratory practice (2021/07/19 - 2021/07/23) Universidade do Porto Faculdade de Farmácia, Portugal
2020/12/10 - 2020/12/17 Jornadas Pedagógico-Científicas Madalena Pinto 20 (2021/12/10 - 2021/12/17) Universidade do Porto Faculdade de Farmácia, Portugal
2019/11 - 2019/11 Jornadas Pedagógico-Científicas Madalena Pinto 19 (2019/11 - 2019/11)
Other (Member of the Scientific Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2019/07/09 - 2019/07/11 Summer Course Drugs: how to obtain, how do they work and why: a perspective in Pharmaceutical Medicinal Chemistry (2019/07/09 - 2019/07/11)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2018/10 - 2018/10 I Conferência Eletrónica em Química Orgânica e Farmacêutica (2018/10 - 2018/10)
Other (Member of the Scientific Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2017/06/27 - 2017/06/29 Summer Course “Drugs: how to obtain, how do they work and why: a perspective in Pharmaceutical Medicinal Chemistry (2017/06/27 - 2017/06/29)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2016/07/19 - 2016/07/21 Summer Course “Drugs: how to obtain, how do they work and why: a perspective in Pharmaceutical Medicinal Chemistry (2016/07/19 - 2016/07/21)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2015/11 - 2015/11 Jornadas de Química Farmacêutica (2015/11 - 2015/11)
Other (Member of the Scientific Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2015/07/21 - 2015/07/23 Summer Course “Drugs: how to obtain, how do they work and why: a perspective in Pharmaceutical Medicinal Chemistry (2015/07/21 - 2015/07/23)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2014/11 - 2014/11 Jornadas de Química Farmacêutica (2014/11 - 2014/11)
Other (Member of the Scientific Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2012/11 - 2012/11 Jornadas de Química Farmacêutica (2012/11 - 2012/11)
Other (Member of the Scientific Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2012/07/23 - 2012/07/26 Summer Course "Substâncias quirais bioativas: anjos ou demónios" (2012/07/23 - 2012/07/26)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2009/09/19 - 2009/09/23 6th European Conference on Marine Products (2009/09/19 - 2009/09/23)
Congress (Other)
 Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2009/07/06 - 2009/07/10 Summer Course “HPLC: dos Fundamentos à Aplicação” (2009/07/06 - 2009/07/10)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2009/07/06 - 2009/07/09 Summer Course “A Química Medicinal e o Planeamento de Fármacos” (2009/07/06 - 2009/07/10)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2008/11/13 - 2008/11/15 1st National Meeting on Medicinal Chemistry (2008/11/13 - 2008/11/15)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/12/05 Semi-preparative enantioresolution, racemization and enantioselectivity studies with MDPV and binding affinity studies with synthetic cathinones
Supervisor
 Ana Sofia Almeida (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/11/26 Development and evaluation of a Pirkle-type chiral stationary phase for flash chromatography
Supervisor
 Layane Andrade Miranda Gonçalves (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2021/10/25 Synthesis and Antifungal Activity of Aminothioxanthone Derivatives
President of the jury
 Joana Filipa de Olas e Sousa Martins Cardoso (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/10/12 Synthesis of New Polymeric Materials based on Chitosan with Potential Anti Tumor Activity
Supervisor
 Rita Alexandra Ferreira Alves de Lima (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/10/08 Gemini surfactants derived from serine: synthesis, characterization, and application
President of the jury
 Diana Raquel da Silva Rodrigues (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/10/06 Synthesis and neuroprotection studies of new xanthenes and fluorenes
President of the jury
 Márcia Sofia Silva Martins (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/01/15 Síntese de derivados de imidazole e triazole como inibidores da atividade antifúngica
(Thesis) Main arguer
 Ana Sofia dos Santos Vila-Chã (PhD)
Universidade do Minho, Portugal
2020/12/18 Mecanismos de reconhecimento molecular e determinação da afinidade de ligação de catinonas sintéticas à albumina sérica humana, por cromatografia de afinidade de alta eficiência
Supervisor
 Tony Gomes Cardoso (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09/18 Aminothioxanthone derivatives: synthesis, and study of antifungal synergistic effects
President of the jury
 Filipa Daniela Freitas Barbosa (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/07/19 Development of new columns for liquid chromatography based on xanthone derivatives
Supervisor
 Joana Filipa Barbosa Teixeira (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/07/12 Chiral Stationary Phases for Liquid Chromatography.: Development, Enantioseparation and Molecular Recognition Mechanism Studies
Supervisor
 Ye’ Zaw Phyo (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/11/09 Enantioresolution, chiral recognition mechanisms and binding of xanthone derivatives on immobilized human serum albumin by liquid chromatography
Supervisor
 João Pedro Soares Pereira do Carmo (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/02/14 Bioactive Secundary metabolites from marine-derived Fungi
(Thesis) Arguer
 War War May Zin (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/10/27 Development of new chiral stationary phases for liquid chromatography based on marine polymers
Supervisor
 João Luís Pinto Ribeiro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/11/22 Chiral small molecules as P-gP modulators: synthesis and enantioselectivity studies
Supervisor
 Ana Catarina Barros Lopes (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07/29 Chiral derivatives of xanthones: synthesis, enantiomeric purity and effect on human tumor cell lines
Supervisor
 Maria Leticia Carraro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/02/24 Advancing personalized medicine in methotrexate-treated diseases: HPLC-DAD method development for therapeutic drug monitoring
(Thesis) Main arguer
 Mónica Francisco Silva (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2005/05/23 - Current Sociedade Portuguesa de Química Member
2002/07 - Current Ordem dos Farmacêuticos Member

Committee member

Activity description
Role 		Institution / Organization
2018/09 - Current Scientific Committee of the Master Degree in Pharmaceutical Chemistry
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2019 Universidade Júnior da UP, “Da Matéria-prima ao Medicamento: Aprender a dar o Primeiro Passo”
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 Universidade Júnior da UP, “Da Matéria-prima ao Medicamento: Aprender a dar o Primeiro Passo”
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2017 Universidade Júnior da UP, “Da Matéria-prima ao Medicamento: Aprender a dar o Primeiro Passo”
Other
 Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Universidade Júnior da UP, “Da Matéria-prima ao Medicamento: Aprender a dar o Primeiro Passo”
Member
 Universidade do Porto Faculdade de Farmácia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/07/19 - 2021/07/23 Factors affecting the activity of drugs/Molecular recognition in the mechanism of action of drugs Universidade do Porto Faculdade de Farmácia, Portugal
2020/03 - 2020/03 Chiral chromatography e-learning Course “Blue Biotechnology Advanced Tools” Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2019/07/09 - 2019/07/11 Factors affecting the activity of drugs/Molecular recognition in the mechanism of action of drugs Drugs: how to obtain, how do they work and why: a perspective in Pharmaceutical Medicinal Chemistry Universidade do Porto Faculdade de Farmácia, Portugal
2018/06/25 - 2018/06/28 Chiral chromatography Marine Natural Products: Discovery and Structure Elucidation Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2017/06/27 - 2017/06/29 Factors affecting the activity of drugs PHARMACEUTICAL DRUGS: HOW TO OBTAIN, HOW DO THEY WORK AND WHY: A Perspective od Pharmaceutical Medicinal Chemistry Universidade do Porto Faculdade de Farmácia, Portugal
2016/07/19 - 2016/07/21 Factors affecting the activity of drugs Drugs: how do they work and why (a perspective in Pharmaceutical Medicinal Chemistry) Universidade do Porto Faculdade de Farmácia, Portugal
2015/07/21 - 2015/07/23 Factors affecting the activity of drugs Drugs: how do they work and why (a perspective in Pharmaceutical Medicinal Chemistry) Universidade do Porto Faculdade de Farmácia, Portugal
2012/07/23 - 2012/07/26 Enantiomeric resolution Substâncias quirais bioativas: anjos ou demónios Universidade do Porto Faculdade de Farmácia, Portugal
Distinctions

Award

2020 Projeto de Inovação Pedagógica da U. Porto "IUC4: Integração de Unidades Curriculares Básicas e Profissionalizantes", C. Fernandes, C. Afonso, H. Cidade, M.E. Tiritan, M.E. Sousa, M. Guerra
Universidade do Porto, Portugal

Other distinction

2020 Menção honrosa, Oral communication, SIFFUP, “A.S. Almeida, J. Teixeira, C. Fernandes*, M. Pinto, M.E. Tiritan. Synthesis of chiral amino acid derivatives of chrysin as potential anti-tumor agents”
Universidade do Porto Faculdade de Farmácia, Portugal
2017 Best poster: J. Ribeiro, C. Fernandes*, M.E. Tiritan, A.M.S. Silva, M.M.M. Pinto, Preparation of a new chiral stationary phase for liquid chromatography based on a small molecule, in 10º Encontro Nacional de Cromatografia
2017 IUPAC grant to participate in TRAMECH IX 2017 and present the poster: Y.Z. Phyo, C. Fernandes*, M.E. Tiritan, S. Cravo, A.M.S. Silva, A. Kijjoa, M.M.M. Pinto, Analytical applications of xanthone derivatives as chiral selectors for liquid chromatography