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In 2012, Sónia C. Correia received her PhD in Cell Biology from University of Coimbra, Portugal. Thereafter, Sónia C. Correia integrated the Center for Neuroscience and Cell Biology (CNC) as a postdoctoral researcher with a fellowship from the Portuguese Foundation for Science and Technology. Currently, Sónia C. Correia is a Doctorate Researcher at CNC. The scientific career of Sónia has been devoted to demystify the pathological basis of AD in order to identify new and feasible peripheral biomarkers for the early diagnosis of the disease and promising therapeutic targets able to counteract the AD symptomatology and neuropathology in a timely manner. Particularly, Sónia is interested in unveiling the contribution of abnormal mitochondrial dynamics and hampered adaptative response to hypoxia triggered by the family of transcription factors HIFs to the onset and progression of this devastating neurodegenerative disease. Despite an interruption in her scientific career due to two maternity leaves (2016 and 2018), the Curriculum Vitae of Sónia C. Correia includes more than 50 papers in international peer-review journals with an overall h-index=37 or 34 and >5700 or 4000 citations, according to Google Scholar or Scopus respectively. In 2010, Sónia C. Correia won the ASN Neuro Poster Prize sponsored by the American Society of Neurochemistry. Honorable, Sónia was recently recognized as an Expert in Alzheimer Disease by the Expertscape, an online base of biomedical expertise. Currently, Sónia is the principal investigator of an ESCI exploratory research grant.
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Identification

Personal identification

Full name
Sónia Catarina de Sousa Correia

Citation names

  • Correia, Sónia
  • Correia, SC

Author identifiers

Ciência ID
DD1E-9B00-98E2
ORCID iD
0000-0001-5360-2564
Google Scholar ID
https://scholar.google.com/citations?hl=en&user=-HcyPcQAAAAJ
Researcher Id
M-5855-2018
Scopus Author Id
35241909300

Addresses

  • Center for Neuroscience and Cell Biology (CNC) Faculty of Medicine, Polo I, 1st floor University of Coimbra , 3004-504, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2022/11/14 - 2022/11/18
Concluded
 VI Quantitative Fluorescence Microscopy Course (Outros)
Universidade de Coimbra, Portugal
2016/07/01 - 2019/01/31
Concluded
 Pós-doutoramento (Pós-doutoramento)
Major in Biomedicina e Medicina Básica
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/03/01 - 2016/06/30
Concluded
 Pós-doutoramento (Pós-doutoramento)
Major in Ciências da Saúde
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/09/23 - 2013/10/04
Concluded
 Laboratory Animal Science (Diploma de especialização)
Major in FELASA C
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Approved
2012/11/12
Concluded
 Biologia (Doutoramento)
Major in Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"MITOCHONDRIAL PRECONDITIONING-TRIGGERED BRAIN TOLERANCE - IMPLICATIONS FOR ALZHEIMER'S DISEASE AND DIABETES" (THESIS/DISSERTATION)
 Approved - Distinction suma cum laude
2007/07/20
Concluded
 Biologia (Licenciatura)
Major in Ramo Científico (Pré-Bolonha)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Effect of metformin on glucose transportes in the brain of diabetic rats " (THESIS/DISSERTATION)
 God (15)
Affiliation

Science

Category
Host institution 		Employer
2019/02/01 - Current Contracted Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/07/01 - 2019/01/31 Postdoc (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/03/01 - 2016/06/30 Postdoc (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/01 - 2014/03 Visiting Researcher (Research) Case Western Reserve University, United States

Others

Category
Host institution 		Employer
2012/03/01 - 2013/02/28 Research Technician Fellow (BSc) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/01 - 2010/07 Visiting PhD Student Case Western Reserve University, United States
Projects

Contract

Designation Funders
2022/08 - Current An exploratory study of the gender-specific response to hypoxia in Alzheimer's disease
N/A
Principal investigator
European Society for Clinical Investigation
Ongoing
2022/01/01 - Current Zfra 1-31: an early intervention in T2D-associated neurodegeneration
EXPL/MED-FSL/0033/2021
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
10.54499/LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 Zfra 1-31 uma intervenção precoce na neurodegeneração associada à diabetes tipo 2
EXPL/MED-FSL/0033/2021
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/11 - 2015/11 Mitochondrial Trafficking In Alzheimer Disease: Revealing the Role of HUMMR
NIRG-13-282387
Post-doc
Alzheimer's Association
Concluded
2013/06 - 2015/09 Effects of life-long physical activity on brain function in Alzheimer Disease and Aging - Relevance of mitochondrial-mediated mechanisms
grant.Provided by PTCRIS: 126230
Other
Fundação para a Ciência e a Tecnologia
2012/05/01 - 2014/10/31 Impacto da terapia com exendina-4 nos mecanismos moleculares subjacentes à disfunção cerebral associada à diabetes tipo 2 a longo prazo
PTDC/SAU-TOX/117481/2010
Universidade da Beira Interior, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/05 - 2014/10 The impact of exendin-4 therapy in the molecular mechanisms underlying type 2 diabetes-related long-term brain dysfunction
grant.Provided by PTCRIS: 117481
Other
Fundação para a Ciência e a Tecnologia
2011/03/01 - 2013/08/31 Pré-condicionamento via mitocôndria: potencial efeito neuroprotector na doença de Alzheimer
PTDC/SAU-NMC/110990/2009
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/03 - 2013/08 Mitochondrial preconditioning: potential neuroprotective effect in Alzheimer's disease
grant.Provided by PTCRIS: 110990
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
2010/04 - 2013/03 The pathological interaction between diabetes and Alzheimer's disease: exploring the role of brain endothelial mitochondria and uncoupling proteins
grant.Provided by PTCRIS: 103325
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Correia, S.C.; Moreira, P.I.. "Role of mitochondria in neurodegenerative diseases: The dark side of the "Energy factory"". 2018.
  2. Cardoso, S.M.; Correia, S.C.; Carvalho, C.; Moreira, P.I.. "Mitochondria in Alzheimer's disease and diabetes-associated neurodegeneration: License to heal!". 2017.
    10.1007/164_2017_3
  3. Castellani, R.J.; Correia, S.C.; Moreira, P.I.; Perry, G.. "Tackling Alzheimer's Disease by Targeting Oxidative Stress and Mitochondria". 2016.
    10.1016/B978-0-12-802173-6.00018-6
  4. Correia, S.C.; Moreira, P.I.; Perry, G.. "Autophagy in alzheimer’s disease: A cleaning service out-of-order?". 2015.
    10.1007/978-3-319-13939-5_7
  5. Santos, Renato; Correia, Sónia; Cardoso, Susana; Carvalho, Cristina; Candeias, Emanuel; Plácido, Ana; Duarte, ANA; et al. "Role of Mitochondria and Oxidative Stress in Parkinson¿s Disease". In Role of Oxidative Stress in Chronic Diseases, 521-548. United States: CRC Press, 2014.
    Published • 10.1201/b16653-26
  6. Duarte, A.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Cardoso, S.; Plácido, A.I.; et al. "The Janus Face of Insulin in Brain". 2013.
    10.1002/9781118395318.ch5
  7. Carvalho, C.; Santos, R.X.; Cardoso, S.; Correia, S.C.; Moreira, P.I.. "Chronic hypoxia, type 2 diabetes and Alzheimer's disease: A dangerous triad". 2013.
  8. Correia, S.C.; Santos, R.X.; Perry, G.; Zhu, X.; Moreira, P.I.; Smith, M.A.. "Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases". 2012.
    10.1007/978-1-4614-0653-2_16
  9. Cardoso, S.; Carvalho, C.; Correia, S.; Santos, R.X.; Santos, M.S.; Moreira, P.I.. "Mitochondrial uncoupling proteins - therapeutic targets in neurodegeneration?". 2011.
  10. Carvalho, C.; Correia, S.C.; Santos, R.X.; Cardoso, S.; Santos, M.S.; Moreira, P.I.. "Diabetes, mitochondria and brain endothelium dysfunction: A dangerous triad for neurodegeneration?". 2011.
Conference poster
  1. Pinho, Tiffany; Correia, SC; Moreira, PI. "The bittersweet side of O-GlcNacylation in Alzheimer's disease-related mitochondrial abnormalities.". Paper presented in MitoPorto - Mitochondrial Evolution, Metabolism and Disease, 2018.
  2. Pinho, Tiffany; Correia, SC; Moreira, PI. "The bittersweet relation between O-GlcNAcylation and Alzheimer's disease: a focus on mitochondria.". Paper presented in 52nd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) – “Precision medicine for healthy aging”, 2018.
  3. Pinho, Tiffany; Correia, SC; Moreira, PI. "O-GlcNAcylation represents a "sweet" route to tackle abnormal mitochondrial function and neuronal loss in Alzheimer's disease.". Paper presented in MitoPorto - Advances in mitochondrial research, 2017.
  4. Correia, SC; Moreira, PI. "Type 2 diabetic female rat brains are less vulnerable to oxidative stress and Alzheimer disease-related hallmarks: a role for insulin/igf-1/estrogen signaling?". Paper presented in XII CNC Annual Meeting, 2015.
  5. Correia, SC. "Loss of HUMMR participates on mitochondrial traffic jams in Alzheimer's disease.". Paper presented in XIV Meeting of the Portuguese Society for Neurosciences, 2015.
  6. Correia, SC. "Altered mitochondrial transport in Alzheimer's disease – HUMMR as a traffic cop!". Paper presented in 12th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders, 2015.
  7. Correia, SC; Moreira, PI. "Stimulation of mitochondrial biogenesis and mitochondrial elongation during preconditioning: the brain adapting to survive!". Paper presented in 38th FEBS Congress, 2013.
  8. Correia, SC; Moreira, PI. "Effects of type 1 diabetes and insulin therapy on brain mitochondrial dynamics and autophagy.". Paper presented in XIII Meeting of the Portuguese Society for Neuroscience, 2013.
  9. Correia, SC; Moreira, PI. "Mitoplasticity during hypoxic preconditioning: the brain battles to survive!". Paper presented in XIII Meeting of the Portuguese Society for Neuroscience, 2013.
  10. Correia, SC; Moreira, PI. "Tolerância cerebral mediada pelo pré-condicionamento por hipóxia num modelo animal de insulino-resistência central". Paper presented in Annual meeting of the Portuguese Society of Diabetology, 2013.
  11. Correia, SC. "Type 2 diabetic female rats are less vulnerable to Alzheimer’s disease than males: the role of brain insulin/igf-1 and estrogen". Paper presented in 11th International Conference on Alzheimer's & Parkinson's Diseases, 2013.
  12. Correia, SC. "Type 2 diabetes-associated damage in aged rat brain: does gender matter?". Paper presented in 2nd Symposium of PF2MUC, 2012.
  13. Correia, SC. "Does gender influence age-related damage in type 2 diabetic rat brain?". Paper presented in 48th European Association for the Study of Diabetes Meeting 2012, 2012.
  14. Correia, SC. "Diabetes unbalances autophagy and mitochondrial dynamics in the brain.". Paper presented in 8th FENS Forum of Neuroscience, 2012.
  15. Correia, SC. "Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozotocin-induced model of sporadic Alzheimer's disease". Paper presented in 11th International Conference on Alzheimer’s disease, 2011.
  16. Correia, SC. "Neuroprotective effects of hypoxic preconditioning on streptozotocin-induced animal model of sporadic Alzheimer's disease". Paper presented in 11th International Conference on Alzheimer’s disease, 2011.
  17. Correia, SC. "Hypoxic preconditioning prevents cognitive decline and cerebral hypometabolism on streptozotocin-induced animal model of sporadic Alzheimer's disease". Paper presented in XII Meeting of the Portuguese Neuroscience Society, 2011.
  18. Correia, SC. "Mitochondrial abnormalities linked to central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease". Paper presented in 5th National Meeting on Cell Signalling – SINAL 2011, 2011.
  19. Correia, SC. "Doxorubicin impairs Ca2+ buffering capacity and oxidative status of brain mitochondria". Paper presented in 5th National Meeting on Cell Signalling – SINAL 2011, 2011.
  20. Correia, SC. "Effect of hypoxic preconditioning on cognition and brain glucose/ energy metabolism in an animal model of sporadic Alzheimer's disease". Paper presented in 10th International Congress on Alzheimer's & Parkinson's Diseases, 2011.
  21. Correia, SC. "Evidence for mitochondrial defects associated with central insulin resistance in streptozotocin-induced model of sporadic Alzheimer’s disease". Paper presented in Models of dementia; the good, the bad and the future, 2010.
  22. Correia, SC. "Mitochondrial reactive oxygen species preconditioning protects brain cells against hyperglycemia". Paper presented in 10th International Conference on Alzheimer’s disease, 2010.
  23. Correia, SC. "Mitochondrial ROS preconditioning protects rat brain endothelial cells against glucotoxicity through HIF-1 activation". Paper presented in XXIVth International Symposium on Cerebral Blood Flow, Metabolism and Function & IXth International Conference on Quantification of Brain Function with PET, 2009.
  24. Correia, SC. "Metformin attenuates type 2 diabetes-induced brain oxidative imbalance". Paper presented in XXIVth International Symposium on Cerebral Blood Flow, Metabolism and Function & IXth International Conference on Quantification of Brain Function with PET, 2009.
  25. Correia, SC. "Mitochondrial reactive oxygen species preconditioning activates hypoxia inducible factor 1 alpha protecting brain endothelial cells against glucotoxicity". Paper presented in International Courses on Toxicology 2009 “Mitochondria: Between Life and Death”, 2009.
  26. Correia, SC. "Metformin attenuates diabetes-induced brain oxidative stress.". Paper presented in SFRR-E Free Radical Summer School 2008 “Lipid Peroxidation- and Free Radical-Signalling: Roles in Pathophysiology”, 2008.
  27. Correia, SC. "Brain mitochondria as a potential target of doxorubicin action". Paper presented in International Courses on Toxicology 2008 “Metabolic Toxicology: from pathway to organism”, 2008.
  28. Correia, SC. "Metformin affects rat liver mitochondria". Paper presented in International Courses on Toxicology 2008 “Metabolic Toxicology: from pathway to organism”, 2008.
Journal article
  1. Cardoso, Susana; Carvalho, Cristina; Correia, Sónia C.; Moreira, Paula I.. "Protective effects of 2,4-dinitrophenol in okadaic acid-induced cellular model of Alzheimer's disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1870 6 (2024): 167222. http://dx.doi.org/10.1016/j.bbadis.2024.167222.
    10.1016/j.bbadis.2024.167222
  2. Susana Cardoso; Cristina Carvalho; Sónia C. Correia. "Special Issue: “Alzheimer’s Disease—115 Years after Its Discovery”". Biomedicines (2024): https://doi.org/10.3390/biomedicines12030478.
    10.3390/biomedicines12030478
  3. Carvalho, Cristina; Correia, Sónia C.; Seiça, Raquel; Moreira, Paula I.. "WWOX inhibition by Zfra1-31 restores mitochondrial homeostasis and viability of neuronal cells exposed to high glucose". Cellular and Molecular Life Sciences 79 9 (2022): http://dx.doi.org/10.1007/s00018-022-04508-7.
    10.1007/s00018-022-04508-7
  4. Sónia C. Correia; Marco G. Alves; Pedro F. Oliveira; Gemma Casadesus; Joseph LaManna; George Perry; Paula I. Moreira. "Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria". Antioxidants & Redox Signaling (2022): https://doi.org/10.1089/ars.2019.8007.
    10.1089/ars.2019.8007
  5. Sónia C. Correia; Paula I. Moreira. "Oxygen Sensing and Signaling in Alzheimer’s Disease: A Breathtaking Story!". Cellular and Molecular Neurobiology (2021): https://doi.org/10.1007/s10571-021-01148-6.
    10.1007/s10571-021-01148-6
  6. Correia, SC. "Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease.". Molecular neurobiology (2021): https://doi.org/10.1007/s12035-021-02316-x.
    10.1007/s12035-021-02316-x
  7. Sónia C. Correia; Nuno J. Machado; Marco G. Alves; Pedro F. Oliveira; Paula I. Moreira. "Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer’s Disease". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms22010461.
    10.3390/ijms22010461
  8. Correia, Sónia. "Post-translational modifications in brain health and disease.". Biochimica et biophysica acta. Molecular basis of disease (2019): https://doi.org/10.1016/j.bbadis.2019.05.006.
    10.1016/j.bbadis.2019.05.006
  9. Correia, Sónia. "Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer's Disease.". Advances in experimental medicine and biology (2019): https://doi.org/10.1007/978-981-13-3540-2_9.
    10.1007/978-981-13-3540-2_9
  10. Pinho, T.S.; Verde, D.M.; Correia, S.C.; Cardoso, S.M.; Moreira, P.I.. "O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease". Ageing Research Reviews 46 (2018): 32-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047295110&partnerID=MN8TOARS.
    10.1016/j.arr.2018.05.003
  11. Pinho, T.S.; Correia, S.C.; Perry, G.; Ambrósio, A.F.; Moreira, P.I.. "Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies". Biochimica et Biophysica Acta - Molecular Basis of Disease (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85056598044&partnerID=MN8TOARS.
    10.1016/j.bbadis.2018.10.037
  12. Candeias, E.; Duarte, A.I.; Sebastião, I.; Fernandes, M.A.; Plácido, A.I.; Carvalho, C.; Correia, S.; et al. "Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology". Molecular Neurobiology 54 8 (2017): 6471-6489. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991075553&partnerID=MN8TOARS.
    10.1007/s12035-016-0155-1
  13. Cardoso, S.; Carvalho, C.; Correia, S.C.; Seiça, R.M.; Moreira, P.I.. "Alzheimer's Disease: From Mitochondrial Perturbations to Mitochondrial Medicine". Brain Pathology 26 5 (2016): 632-647. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988642816&partnerID=MN8TOARS.
    10.1111/bpa.12402
  14. Correia, S.C.; Perry, G.; Moreira, P.I.. "Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks". Biochimica et Biophysica Acta - Molecular Basis of Disease 1862 10 (2016): 1909-1917. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979699672&partnerID=MN8TOARS.
    10.1016/j.bbadis.2016.07.010
  15. Carvalho, C.; Correia, S.C.; Perry, G.; Castellani, R.J.; Moreira, P.I.. "Cerebrovascular and mitochondrial abnormalities in Alzheimer’s disease: a brief overview". Journal of Neural Transmission 123 2 (2016): 107-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957851903&partnerID=MN8TOARS.
    10.1007/s00702-015-1367-7
  16. Correia, S.C.; Resende, R.; Moreira, P.I.; Pereira, C.M.. "Alzheimer's disease-related misfolded proteins and dysfunctional organelles on autophagy menu". DNA and Cell Biology 34 4 (2015): 261-273. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926636149&partnerID=MN8TOARS.
    10.1089/dna.2014.2757
  17. Plácido, A.I.; Pereira, C.M.F.; Duarte, A.I.; Candeias, E.; Correia, S.C.; Carvalho, C.; Cardoso, S.; Oliveira, C.R.; Moreira, P.I.. "Modulation of endoplasmic reticulum stress: An opportunity to prevent neurodegeneration?". CNS and Neurological Disorders - Drug Targets 14 4 (2015): 518-533. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929628537&partnerID=MN8TOARS.
  18. Carvalho, C.; Correia, S.C.; Cardoso, S.; Plácido, A.I.; Candeias, E.; Duarte, A.I.; Moreira, P.I.. "The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases". Expert Review of Neurotherapeutics 15 8 (2015): 867-884. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937838385&partnerID=MN8TOARS.
    10.1586/14737175.2015.1058160
  19. Santos, R.X.; Correia, S.C.; Alves, M.G.; Oliveira, P.F.; Cardoso, S.; Carvalho, C.; Duarte, A.I.; Santos, M.S.; Moreira, P.I.. "Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 7 (2014): 1154-1166. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899789863&partnerID=MN8TOARS.
    10.1016/j.bbadis.2014.04.011
  20. Plácido, A.I.; Pereira, C.M.F.; Duarte, A.I.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; et al. "The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 9 (2014): 1444-1453. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903458925&partnerID=MN8TOARS.
    10.1016/j.bbadis.2014.05.003
  21. Cardoso, S.; Correia, S.; Carvalho, C.; Candeias, E.; Plácido, A.I.; Duarte, A.I.; Seiça, R.M.; Moreira, P.I.. "Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection". Journal of Bioenergetics and Biomembranes 47 1-2 (2014): 119-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922536968&partnerID=MN8TOARS.
    10.1007/s10863-014-9580-x
  22. Carvalho, C.; Correia, S.C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I.. "Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes". Current Neurovascular Research 11 4 (2014): 330-339. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925786114&partnerID=MN8TOARS.
  23. Santos, R.X.; Correia, S.C.; Alves, M.G.; Oliveira, P.F.; Cardoso, S.; Carvalho, C.; Seiça, R.; Santos, M.S.; Moreira, P.I.. "Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes". Molecular and Cellular Biochemistry (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901561690&partnerID=MN8TOARS.
    10.1007/s11010-014-2076-5
  24. Correia, S.C.; Santos, R.X.; Santos, M.S.; Casadesus, G.; LaManna, J.C.; Perry, G.; Smith, M.A.; Moreira, P.I.. "Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease". Current Alzheimer Research 10 4 (2013): 406-419. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878623135&partnerID=MN8TOARS.
    10.2174/1567205011310040006
  25. Cardoso, S.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Candeias, E.; Duarte, A.I.; Plácido, A.I.; Santos, M.S.; Moreira, P.I.. "Hyperglycemia, hypoglycemia and dementia: Role of mitochondria and uncoupling proteins". Current Molecular Medicine 13 4 (2013): 586-601. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876735551&partnerID=MN8TOARS.
    10.2174/1566524011313040010
  26. Carvalho, C.; Machado, N.; Mota, P.C.; Correia, S.C.; Cardoso, S.; Santos, R.X.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I.. "Type 2 diabetic and alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies". Journal of Alzheimer's Disease 35 3 (2013): 623-635. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880196052&partnerID=MN8TOARS.
    10.3233/JAD-130005
  27. Santos, R.X.; Correia, S.C.; Zhu, X.; Smith, M.A.; Moreira, P.I.; Castellani, R.J.; Nunomura, A.; Perry, G.. "Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease". Antioxidants and Redox Signaling 18 18 (2013): 2444-2457. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878619863&partnerID=MN8TOARS.
    10.1089/ars.2012.5039
  28. Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, R.X.; Plácido, A.I.; Candeias, E.; Duarte, A.I.; Moreira, P.I.. "Defective HIF signaling pathway and brain response to hypoxia in neurodegenera-tive diseases: Not an “Iffy” question!". Current Pharmaceutical Design 19 38 (2013): 6809-6822. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884829985&partnerID=MN8TOARS.
  29. Duarte, A.I.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Cardoso, S.; Plácido, A.; et al. "Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration". Biochimica et Biophysica Acta - Molecular Basis of Disease 1832 4 (2013): 527-541. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873306844&partnerID=MN8TOARS.
    10.1016/j.bbadis.2013.01.008
  30. Cardoso, S.; Santos, R.X.; Correia, S.C.; Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I.. "Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance". Neurobiology of Disease 49 1 (2013): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866491588&partnerID=MN8TOARS.
    10.1016/j.nbd.2012.08.008
  31. Correia, S.C.; Perry, G.; Castellani, R.; Moreira, P.I.. "Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?". Journal of Neurochemistry 127 1 (2013): 4-6. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884846458&partnerID=MN8TOARS.
    10.1111/jnc.12406
  32. Santos, R.X.; Correia, S.C.; Zhu, X.; Lee, H.-G.; Petersen, R.B.; Nunomura, A.; Smith, M.A.; Perry, G.; Moreira, P.I.. "Nuclear and mitochondrial DNA oxidation in Alzheimer's disease". Free Radical Research 46 4 (2012): 565-576. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863229887&partnerID=MN8TOARS.
    10.3109/10715762.2011.648188
  33. Correia, S.C.; Santos, R.X.; Carvalho, C.; Cardoso, S.; Candeias, E.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I.. "Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation". Brain Research 1441 (2012): 64-78. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857788978&partnerID=MN8TOARS.
    10.1016/j.brainres.2011.12.063
  34. Carvalho, C.; Cardoso, S.; Correia, S.C.; Santos, R.X.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I.. "Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities". Diabetes 61 5 (2012): 1234-1242. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860599622&partnerID=MN8TOARS.
    10.2337/db11-1186
  35. Correia, S.C.; Santos, R.X.; Cardoso, S.M.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I.. "Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1a". Neurobiology of Disease 45 1 (2012): 206-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-81955160758&partnerID=MN8TOARS.
    10.1016/j.nbd.2011.08.005
  36. Candeias, E.; Duarte, A.I.; Carvalho, C.; Correia, S.C.; Cardoso, S.; Santos, R.X.; Plácido, A.I.; Perry, G.; Moreira, P.I.. "The impairment of insulin signaling in Alzheimer's disease". IUBMB Life 64 12 (2012): 951-957. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870197271&partnerID=MN8TOARS.
    10.1002/iub.1098
  37. Correia, S.C.; Santos, R.X.; Cardoso, S.; Carvalho, C.; Candeias, E.; Duarte, A.I.; Plácido, A.I.; Santos, M.S.; Moreira, P.I.. "Alzheimer disease as a vascular disorder: Where do mitochondria fit?". Experimental Gerontology 47 11 (2012): 878-886. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867725518&partnerID=MN8TOARS.
    10.1016/j.exger.2012.07.006
  38. Correia, S.C.; Cardoso, S.; Santos, R.X.; Carvalho, C.; Santos, M.S.; Perry, G.; Smith, M.A.; Moreira, P.I.. "New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection". Current Pharmaceutical Design 17 31 (2011): 3381-3389. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055089996&partnerID=MN8TOARS.
    10.2174/138161211798072490
  39. Santos, R.X.; Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, M.S.; Moreira, P.I.. "Mitophagy in neurodegeneration: An opportunity for therapy?". Current Drug Targets 12 6 (2011): 790-799. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955585040&partnerID=MN8TOARS.
    10.2174/138945011795528813
  40. Carvalho, C.; Correia, S.C.; Santos, R.X.; Cardoso, S.; Moreira, P.I.; Zhu, X.; Smith, M.A.; Perry, G.. "Association of mitochondrial signaling in Alzheimer's disease and hypoxia". Molecular Aspects of Neurodegeneration and Neuroprotection (2011): 50-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884443449&partnerID=MN8TOARS.
    10.2174/978160805092511101010050
  41. Correia, S.C.; Santos, R.X.; Perry, G.; Zhu, X.; IMoreira, P.I.; Smith, M.A.. "Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?". Ageing Research Reviews 10 2 (2011): 264-273. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952449386&partnerID=MN8TOARS.
    10.1016/j.arr.2011.01.001
  42. Santos, R.X.; Correia, S.C.; Cardoso, S.; Carvalho, C.; Santos, M.S.; Moreira, P.I.. "Effects of rapamycin and TOR on aging and memory: Implications for Alzheimer's disease". Journal of Neurochemistry 117 6 (2011): 927-936. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957971392&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2011.07262.x
  43. Cardoso, S.; Carvalho, C.; Santos, R.; Correia, S.; Santos, M.S.; Seiça, R.; Oliveira, C.R.; Moreira, P.I.. "Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters". Synapse 65 6 (2011): 457-466. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953276927&partnerID=MN8TOARS.
    10.1002/syn.20863
  44. Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, R.X.; Santos, M.S.; Oliveira, C.R.; Perry, G.; et al. "Mitochondrial preconditioning: A potential neuroprotective strategy". Frontiers in Aging Neuroscience 2 AUG (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-79955962818&partnerID=MN8TOARS.
    10.3389/fnagi.2010.00138
  45. Correia, S.C.; Moreira, P.I.. "Hypoxia-inducible factor 1: A new hope to counteract neurodegeneration?". Journal of Neurochemistry 112 1 (2010): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-71649085107&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2009.06443.x
  46. Correia, S.C.; Santos, R.X.; Perry, G.; Zhu, X.; Moreira, P.I.; Smith, M.A.. "Mitochondria: The missing link between preconditioning and neuroprotection". Journal of Alzheimer's Disease 20 SUPPL.2 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77956220265&partnerID=MN8TOARS.
    10.3233/JAD-2010-100669
  47. Correia, S.C.; Santos, R.X.; Cardoso, S.; Carvalho, C.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I.. "Effects of estrogen in the brain: Is it a neuroprotective agent in alzheimer's disease?". Current Aging Science 3 2 (2010): 113-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953736213&partnerID=MN8TOARS.
    10.2174/1874609811003020113
  48. Santos, R.X.; Cardoso, S.; Correia, S.; Carvalho, C.; Santos, M.S.; Moreira, P.I.. "Targeting autophagy in the brain: A promising approach?". Central Nervous System Agents in Medicinal Chemistry 10 2 (2010): 158-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953681716&partnerID=MN8TOARS.
  49. Santos, R.X.; Correia, S.C.; Wang, X.; Perry, G.; Smith, M.A.; Moreira, P.I.; Zhu, X.. "A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease". Journal of Alzheimer's Disease 20 SUPPL.2 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77956199031&partnerID=MN8TOARS.
    10.3233/JAD-2010-100666
  50. Santos, R.X.; Correia, S.C.; Wang, X.; Perry, G.; Smith, M.A.; Moreira, P.I.; Zhu, X.. "Alzheimer's disease: Diverse aspects of mitochondrial malfunctioning". International Journal of Clinical and Experimental Pathology 3 6 (2010): 570-581. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956026971&partnerID=MN8TOARS.
  51. Carvalho, C.; Santos, R.X.; Cardoso, S.; Correia, S.; Oliveira, P.J.; Santos, M.S.; Moreira, P.I.. "Doxorubicin: The good, the bad and the ugly effect". Current Medicinal Chemistry 16 25 (2009): 3267-3285. http://www.scopus.com/inward/record.url?eid=2-s2.0-70450215499&partnerID=MN8TOARS.
    10.2174/092986709788803312
  52. Carvalho, C.; Correia, S.C.; Santos, R.X.; Cardoso, S.; Moreira, P.I.; Clark, T.A.; Zhu, X.; Smith, M.A.; Perry, G.. "Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia". Journal of Bioenergetics and Biomembranes 41 5 (2009): 433-440. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449397210&partnerID=MN8TOARS.
    10.1007/s10863-009-9247-1
  53. Cardoso, S.; Correia, S.; Santos, R.X.; Carvalho, C.; Santos, M.S.; Oliveira, C.R.; Perry, G.; et al. "Insulin is a two-edged knife on the brain". Journal of Alzheimer's Disease 18 3 (2009): 483-507. http://www.scopus.com/inward/record.url?eid=2-s2.0-75249106915&partnerID=MN8TOARS.
  54. Santos, R.X.; Cardoso, S.; Silva, S.; Correia, S.; Carvalho, C.; Crisóstomo, J.; Rodrigues, L.; et al. "Food deprivation promotes oxidative imbalance in rat brain". Journal of Food Science 74 1 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-58649112769&partnerID=MN8TOARS.
    10.1111/j.1750-3841.2008.00982.x
  55. Carvalho, C.; Correia, S.; Santos, M.S.; Seiça, R.; Oliveira, C.R.; Moreira, P.I.. "Metformin promotes isolated rat liver mitochondria impairment". Molecular and Cellular Biochemistry 308 1-2 (2008): 75-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-38649115973&partnerID=MN8TOARS.
    10.1007/s11010-007-9614-3
  56. Correia, S.; Carvalho, C.; Santos, M.S.; Seiça, R.; Oliveira, C.R.; Moreira, P.I.. "Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview.". Mini reviews in medicinal chemistry 8 13 (2008): 1343-1354. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149377770&partnerID=MN8TOARS.
    10.2174/138955708786369546
  57. Correia, S.; Carvalho, C.; Santos, M.S.; Proença, T.; Nunes, E.; Duarte, A.I.; Monteiro, P.; et al. "Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes". Medicinal Chemistry 4 4 (2008): 358-364. http://www.scopus.com/inward/record.url?eid=2-s2.0-50049125341&partnerID=MN8TOARS.
    10.2174/157340608784872299
  58. Cardoso, S.; Santos, R.X.; Carvalho, C.; Correia, S.; Pereira, G.C.; Pereira, S.S.; Oliveira, P.J.; et al. "Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage". Free Radical Biology and Medicine 45 10 (2008): 1395-1402. http://www.scopus.com/inward/record.url?eid=2-s2.0-54349099428&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2008.08.008
  59. Cardoso, Susana; Santos, Renato X.; Carvalho, Cristina; Correia, Sónia; Pereira, Gonçalo C.; Pereira, Susana S.; Oliveira, Paulo J.; et al. "Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage". (2008): http://hdl.handle.net/10316/10086.
    https://doi.org/10.1016/j.freeradbiomed.2008.08.008
Journal issue
  1. Correia, Sónia. "Mitochondrial Footprint in Neurological Pathology". International Journal of Molecular Science (2023): https://www.mdpi.com/journal/ijms/special_issues/E13124A195.
    Invited editor
  2. "Mitochondria in Neurodegenerative Disorders: When the Powerhouse Fails!". International Journal of Molecular Sciences (2022): https://www.mdpi.com/journal/ijms/special_issues/mitochondria_neuro.
  3. "State-of-the-Art Neurobiology and Neurologic Disease in Portugal". Biomedicines (2022): https://www.mdpi.com/journal/biomedicines/special_issues/neurobiology_Portugal.
    Invited editor
  4. Correia, SC; Susana Cardoso; Cristina Carvalho (621D-4A1A-D4A4). "Alzheimer's Disease - 115 Years after Its Discovery". Biomedicines (2021): https://www.mdpi.com/journal/biomedicines/special_issues/Alzheimer_115.
    In press • Invited editor
  5. Correia, SC. "Molecular Mechanisms of Alzheimer's Disease and Brain Tolerance". International Journal of Molecular Sciences (2021): https://www.mdpi.com/journal/ijms/special_issues/AD_mechanisms.
    In press • Invited editor
  6. Correia, SC. "Post-Translational Modifications in Brain Health and Disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865 8 (2020): https://www.sciencedirect.com/journal/biochimica-et-biophysica-acta-bba-molecular-basis-of-disease/vol/1865/issue/8.
Newspaper article
  1. Correia, SC. "Doenças neurodegenerativas: um quebra-cabeças com solução à vista", Público, 2021
  2. Correia, SC. "Viagens sem insónias, a Comics written together with other researchers from CNC.IBILI about the "World Sleep Day 2018"", Público, 2018, https://www.publico.pt/2018/03/16/ciencia/fotogaleria/viagens-sem-insonias-381315.
  3. Correia, SC. "Viagens na Diabetes, a Comics written together with other researchers from CNC.IBILI about the "World Diabetes Day 2017"", Público, 2017, https://www.publico.pt/2017/11/14/fotogaleria/viagens-na-diabetes-em-bd-378982.
Thesis / Dissertation
  1. Correia, SC. "Mitochondrial preconditioning-triggered brain tolerance – implications for Alzheimer’s disease and diabetes.". PhD, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2012. http://hdl.handle.net/10316/21231.

Artistic / Performance

Video recording
  1. Correia, SC. 2021. A demência é algo que só acontece à população idosa?.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/04 Hypoxia in Alzheimer's disease DCV.talks
Universidade de Coimbra (Coimbra, Portugal)
2023/06/09 Altered hypoxic response in Alzheimer's disease patient-derived fibroblasts: what (H)IF gender matters? 57th Annual Meeting of the European Society for Clinical Investigation
(Praga, Czech Republic)
2021/07/02 Loss of HUMMR as a potential 'roadblock' for mitochondrial movement in Alzheimer's disease 35th Meeting of the Portuguese Group of Studies on Aging and Dementia GEECD - Webinar
2021/06 Hypoxia preconditioning-triggered mitochondrial remodeling in a rat model of sporadic Alzheimer's disease: a "breath of fresh air" towards effective treatment? 55th Annual Scientific Meeting of the European Society for Clinical Investigation
2020/09/26 Hypoxic preconditioning averts sporadic Alzheimer's disease-like phenotype in rats: the role of mitochondrial remodeling 34th Meeting of the Portuguese Group of Studies on Aging and Dementia GEECD – Webinar
2019/05/23 Loss of HUMMR in Alzheimer's disease acts as a "red traffic light" on the mitochondrial movement. 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
(Coimbra, Portugal)
2017/12/21 The molecular roadblocks underlying mitochondrial traffic jam in Alzheimer’s disease. 2nd Meeting on Biomedical Research @ UC
(Coimbra, Portugal)
2017/09/15 Mitochondrial movement in Alzheimer's disease: don't stop me now! CNC.IBILI Seminars
(Coimbra, Portugal)
2017/05/26 Mitochondrial traffic jams in Alzheimer's disease - HUMMR as a roadblock MitoPorto - Advances in mitochondrial research
(Porto, Portugal)
2015/11/20 HUMMR acts as a “roadblock” for mitochondrial transport in Alzheimer’s disease. II CISGP - Promoting health technologies: from diagnosis to intervention
(Porto, Portugal)
2014/06/28 Brain endothelial protection by pinacidil preconditioning in an okadaic acid-induced Alzheimer’s disease model: role of mitoKATP channels, ROS and HIF-1a 28ª Reunião do Grupo de Estudo de Envelhecimento Cerebral e Demências
(Aveiro, Portugal)
2014/04/19 Reprogramming of the mitochondrial biology in hypoxic preconditioning-triggered brain tolerance 47th Annual Scientific Meeting of the European Society for Clinical Investigation
(Albufeira, Portugal)
2011/06 Hypoxic preconditioning mediates endogenous neuroprotection in streptozotocin-induced animal model of sporadic Alzheimer's disease 25ª Reunião do Grupo de Estudo de Envelhecimento Cerebral e Demências
(Tomar, Portugal)
2009/11 Protection by mitochondrial ROS preconditioning: HIF-1a as a novel candidate to minimize high glucose-associated brain endothelium damage Advanced Course on Mitochondrial Bioenergetics “Mitochondria: From the Basics to the Clinic”
(Coimbra, Portugal)
2009/05 Doxorubicin promotes Ca2+-induced mitochondrial permeability transition and oxidative damage in brain mitochondria International Courses on Toxicology 2009 “Mitochondria: Between Life and Death”
(Coimbra, Portugal)
2008/04 Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes International Courses on Toxicology 2008 “Metabolic Toxicology: from pathway to organism”
(Coimbra, Portugal)
2007/12 Metformin counteracts the oxidative imbalance that occurs in the brain of diabetic Goto-Kakizaki rats. XXXVIII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXV Reunião de Farmacologia Clínica; VII Reunião de Toxicologia
(Coimbra, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/02 - 2020/07/27 The role of hypoxia and hypoxia-inducible factors in Alzheimer's disease (Project Report)
Supervisor of Pedro Rafael Marques Boto
 Bioquímica (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/04/29 - 2019/12/03 Qual o papel do HIF-1 alfa nas alterações mitocondriais associadas à doença de Alzheimer?
Supervisor
 Biotecnologia
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2017/11/01 - 2018/10/01 MSc Research Fellow - HEALTHYAGING 2020 (CENTRO-01-0145-FEDER-000012)
Co-supervisor of Tiffany Pinho Santos
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015 - 2016 Protective effects of hypoxic preconditioning against sporadic Alzheimer’s disease-like pathology-focus on insulin signaling, mitochondrial dynamics and autophagy
Co-supervisor
 Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2015 Revealing the role of HUMMR in mitochondrial trafficking impairment in Alzheimer’s disease
Co-supervisor
 Anatomia Patológica, Citológica e Tanatológica
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/12/15 - 2022/12/15 Alzheimer's Disease: The History of Forgetting| Biomedicines webinar (2022/12/15 - 2022/12/15)
Seminar (Co-organisor)
 Multidisciplinary Digital Publishing Institute AG, Switzerland
2021/11/17 - 2021/11/18 2nd Retreat of CIBB's Metabolism, Aging and Disease Area (2021/11/17 - 2021/11/18)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009 International Courses on Toxicology “Mitochondria: between life and death” (2009 - 2009)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2018/11/28 - Current Science outreach activities to students from Elementary School (8-9 years old), integrated in the Escola Ciência Viva, organized by Ciência Viva Rómulo de Carvalho
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008 - Current Brain Awareness Week
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/12/07 HYPOXIA-INDUCED QUIESCENCE: A NEW APPROACH ON MSC PRESERVATION
(Thesis) Main arguer
 Inês Carmona Lameiras e Silva Moniz (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/02/24 Linking mitochondrial Src and hippocampal dendritic changes in Alzheimer's disease
(Thesis) Main arguer
 Laura Alexandrina Sequeira Neves (Master)
Universidade de Coimbra, Portugal

Committee member

Activity description
Role 		Institution / Organization
2021/01 - Current Editorial Board Member : Biomedicines
Member
 Multidisciplinary Digital Publishing Institute AG, Switzerland
2021 - Current Editorial Board Member - Review Editor- Frontiers in Cellular Neuroscience| Cellular Neuropathology
Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/10 - 2024/02 Investigação Aplicada I Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2023/02 - 2023/07 Projecto da Licenciatura em Bioquímica Bioquímica Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2023/02 - 2023/07 Investigação Aplicada II Medicina Universidade de Coimbra Faculdade de Medicina, Portugal
2019/04/10 - 2019/04/10 Hypoxia in Alzheimer's disease - an old enemy? PDBEB - Advanced Courses on Neurodegenerative disorders (Doutoramento) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/02 - 2014/02 Alzheimer’s disease: the brain diabetes! Spring 2014 Cell & Molecular Biology Seminar Series University of Texas at San Antonio Department of Biology, United States
2013/06 - 2013/06 The triple transgenic mouse model as an experimental tool to unveil Alzheimer mechanisms and therapeutic strategies - Invited Lecturer Ciências Biomédicas (Mestrado integrado) Universidade da Beira Interior, Portugal
2012/12 - 2012/12 Effect of Preconditioning on autophagy PDBEB - Advanced Course on Biology of proteolysis in pathology (Doutoramento) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2010/05 - Current Evaluator of applications - NIH Research Project Grant National Institutes of Health, United States
2024/01 - 2024/01 2024 January Alzheimer's Association Research Fellowship Review Committee
Evaluator
 Alzheimer's Association, United States Alzheimer's Association
2022/01 - 2022/01 2022 January Alzheimer's Association Research Fellowship Review Committee
Evaluator
 Alzheimer's Association, United States
2021/04 - 2021/06 Evaluator of applications - Alzheimer's Association Research Fellowship Program Alzheimer's Association, United States Alzheimer's Association
2019 - 2020 Evaluator of applications - Alzheimer's Association Research Fellowship Program
Evaluator
 Alzheimer's Association, United States
2019/11 - 2019/11 Juri of the applications for a Research Fellowship for a Master-holder (BIM) funded by the project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012)
Evaluator
2019/10 - 2019/10 Juri of the applications for a Research Fellowship for a Master-holder (BIM) funded by the project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012)
Evaluator
2019/05 - 2019/05 Poster Evaluator in the 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI2019) -Symposium 8: Neurobiology of Aging
Evaluator

Journal scientific committee

Journal title (ISSN) Publisher
2024/03 - Current Cell Communication and Signaling Springer Nature
2024/02 - Current Cell Biochemistry and Biophysics Springer
2023/08 - Current Mitochondrion Elsevier’s
2021 - Current Antioxidants
2020 - Current Antioxidants and Redox Signaling (1523-0864) Mary Ann Liebert
2020 - Current Neurochemical Research (1573-6903) Springer-Verlag
2020 - Current International Journal of Molecular Sciences
2018 - Current Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (0925-4439) Elsevier
2017 - Current Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2016 - Current BioMed Research International
2016 - Current Neuroscience Letters (0304-3940) Elsevier
2016 - Current CNS Drugs (1179-1934) Springer-Verlag
2015 - Current NeuroToxicology
2015 - Current Journal of Neurochemistry (1471-4159) Wiley (Blackwell Publishing)
2015 - Current British Journal of Pharmacology
2014 - Current Frontiers in Aging Neuroscience (1663-4365) Frontiers Media SA
2013 - Current Experimental Gerontology (0531-5565) Elsevier
2011 - Current Pharmacology Biochemistry and Behavior (0091-3057) Elsevier
2011 - Current Cell Stress and Chaperones (1466-1268) Springer-Verlag
2011 - Current CNS & Neurological Disorders - Drug Targets (1871-5273) Bentham Science
2010 - Current Acta Neurobiologiae Experimentalis (1689-0035) "Exeley, Inc."
2010 - Current Redox Report (1351-0002) Maney Publishing
2010 - Current International Journal of Alzheimer s Disease (2090-0252) Hindawi Limited
2010 - Current FEBS Journal (1742-4658) Wiley (Blackwell Publishing)
2010 - 2020 Journal of Alzheimer s Disease (1875-8908) IOS Press
2015 - 2015 The Journal of Sports Medicine (0090-4201) SAGE Publications
2014 - 2014 Brain Research
2010 - 2010 Proceedings of the National Academy of Sciences (1091-6490) Proceedings of the National Academy of Sciences

Mentoring / Tutoring

Topic Student name
2019 - 2019 MSc in Cellular and Molecular Biology (University of Coimbra) - Lab rotation Ana Sofia Silva
2019 - 2019 Erasmus Internship Federica Del Giacco
2017 - 2017 Estágios de Verão para Estudantes de Medicina - CECEFs Ana Jorge
2016 - 2017 MSc in Cellular and Molecular Biology - Thesis Tiffany Santos Pinho
2016 - 2016 MSc in Medicine (University of Coimbra) - Investigation Chair Project André Coimbra Trigo
2015 - 2015 MSc in Cellular and Molecular Biology (University of Coimbra) - Lab rotation Filipe Nunes Vicente
2015 - 2015 MSc in Biomedical Investigation (University of Coimbra) - Lab rotation Daniela Madeira
2013 - 2014 MSc in Cellular and Molecular Biology - Thesis Rui Fernando Simões
2012 - 2012 BSc in Biomedical Sciences - Project Report Joana Portela Domingues
2011 - 2011 MSc in Cellular and Molecular Biology (University of Coimbra) - Lab rotation Joana Rodrigues
Distinctions

Award

2015 Mantero Belard Prize
Santa Casa da Misericórdia de Lisboa, Portugal
2010 ASN Neuro Poster Prize

Other distinction

2021 Expertscape Expert in Alzheimer Disease
2019 Travel grant to attend the "53rd Annual Scientific Meeting of the European Society for Clinical Investigation"
2016 Postdoctoral fellowship (SFRH/BPD/109822/2015)
Fundação para a Ciência e a Tecnologia, Portugal
2015 Travel grant to attend the “6th Annual Alliance for Healthy Ageing Conference” in Newcastle (UK)
2013 Postdoctoral fellowship (SFRH/BPD/84163/2012)
Fundação para a Ciência e a Tecnologia, Portugal
2013 Federation of the Societies of Biochemistry and Molecular Biology (FEBS) bursary for participation in a congress
2010 S&T-R&D grants for short-term research in the US.
Fundação Luso-Americana, Portugal
2008 PhD fellowship (SFRH/BD/40702/2007)
Fundação para a Ciência e a Tecnologia, Portugal
2008 Federation of the Societies of Biochemistry and Molecular Biology (FEBS) Youth Travel Fellowship (YTF) for participation in an advanced course