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Identification

Personal identification

Full name
Afonso Machado Mendes

Citation names

  • Mendes, Afonso

Author identifiers

Ciência ID
DE1C-91E4-7730
ORCID iD
0000-0001-7324-555X

Telephones

Mobile phone
  • (+351) 914916193 (Personal)

Addresses

  • Praceta Guerra Junqueiro 5 5º Esquerdo, 2790-083, Carnaxide, Oeiras, Portugal (Personal)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biology
  • Natural sciences - Biological Sciences - Virology
  • Medical and Health Sciences - Basic Medicine - Immunology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Elementary (A2) Intermediate (B1) Beginner (A1) Upper intermediate (B2)
Education
Degree Classification
2020/09/01 - 2024/12/01
Ongoing
 Integrative Biology and Biomedicine (Doutoramento)
Instituto Gulbenkian de Ciência, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09/01 - 2019/12/01
Concluded
 Biomedical Research (Mestrado)
Major in Ageing and Chronic Diseases
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
"Mechanisms underlying exosomal traffickinbg of the antiretroviral factor APOBEC3G: Implications for the containment and eradication of HIV-1 infection" (THESIS/DISSERTATION)
 20/20
2015/09/15 - 2017/07/15
Concluded
 Biologia (Licenciatura)
Major in Biologia Molecular e Genética
Universidade de Lisboa Faculdade de Ciências, Portugal
"Influence of mycorrhization in Quercus suber's response to drought: Analysis of the expression of genes involved in lipid metabolism" (THESIS/DISSERTATION)
 13.4/20
Affiliation

Science

Category
Host institution 		Employer
2019/09/01 - Current Researcher (Research) Instituto Gulbenkian de Ciência, Portugal
Instituto Gulbenkian de Ciência, Portugal
(...)
2018/09/01 - 2019/08/01 Researcher (Research) Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Projects

Grant

Designation Funders
2021/09/01 - Current Enabling live-cell 4D super-resolution microscopy guided by artificial intelligence
101001332
PhD Student Fellow
European Research Council
Ongoing

Contract

Designation Funders
2020/04/15 - Current Um teste de detecção do RNA Sars-Cov-2 em zaragatoas ultra-sensível, específico, rápido e barato: PCR “nested“ em tubo único com detecção colorimétrica.
ANI - to be attributed
Researcher
Ongoing
2018/01/01 - Current Activation-Induced Cytidine Deaminase as a guardian of the genome
IF/01721/2014
Researcher
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Outputs

Publications

Journal article
  1. Afonso Mendes; Hannah S. Heil; Simao Coelho; Christophe Leterrier; Ricardo Henriques. "Mapping molecular complexes with super-resolution microscopy and single-particle analysis". Open Biology (2022): https://doi.org/10.1098/rsob.220079.
    10.1098/rsob.220079
  2. Mario Del Rosario; Hannah S. Heil; Afonso Mendes; Vittorio Saggiomo; Ricardo Henriques. "The Field Guide to 3D Printing in Optical Microscopy for Life Sciences". Advanced Biology 6 4 (2022): 2100994-2100994. https://doi.org/10.1002/adbi.202100994.
    10.1002/adbi.202100994
  3. Mendes, Afonso; Vicente, Manuel M; Cruz, Margarida R.; Vicente, José R.; Barreto, Vasco M.. "A CyclinB2-Cas9 fusion promotes the homology-directed repair of double-strand breaks". bioRxiv (2019): https://doi.org/10.1101/555144.
    Open access • Published • 10.1101/555144
Preprint
  1. Afonso Mendes; Bruno M. Saraiva; Guillaume Jacquemet; João I. Mamede; Christophe Leterrier; Ricardo Henriques. "Structural Repetition Detector: multi-scale quantitative mapping of molecular complexes through microscopy". 2024. https://doi.org/10.1101/2024.09.16.613204.
    10.1101/2024.09.16.613204
  2. "Mapping molecular complexes with Super-Resolution Microscopy and Single-Particle Analysis". 2022. https://arxiv.org/abs/2202.08765.
    10.48550/ARXIV.2202.08765
  3. "The Field Guide to 3D Printing in Microscopy". 2021. http://dx.doi.org/10.20944/preprints202105.0352.v1.
    10.20944/preprints202105.0352.v1
Thesis / Dissertation
  1. Mendes, Afonso Machado. "Mechanisms underlying exosomal trafficking of the antiretroviral factor apobec3g: implications for the containment and eradication of HIV-1 infection". Master, 2019. http://hdl.handle.net/10362/93640.

Other

Other output
  1. A First Exposure to Super-Resolution Microscopy. 2021. Afonso Mendes. https://doi.org/10.1242/focalplane.4801.
    10.1242/focalplane.4801
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/04/11 Super Redundancy: a template-free intensity-based single particle analysis framework FOM2022
2021/01/21 Mechanisms underlying the packaging of the antiretroviral factor APOBEC3G into exosomes. Deaminet 2021: 2nd International Conference on Base Editing - Enzymes and Applications
University of Minnesota, Minnesota, USA (Minnesota, United States)
2020/03/06 Mechanisms underlying exosomal trafficking of the antiretroviral factor APOBEC3G: Implications for the containment and eradication of HIV-1 infection Casual Fridays at CEDOC
CEDOC - Center for Chronic Diseases (Lisboa, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/10/13 - Current Virus Entry and Post-Entry Events
Conference
 Virus Entry and Post-Entry Events
National Cancer Institute, United States
2021/11/23 - 2021/11/25 SPAOM 2021
Conference
 SPAOM 2021
Instituto Gulbenkian de Ciência, Portugal
2021/03/28 - 2021/03/31 FOM2021
Conference
 FOM2021