???global.info.a_carregar???
Sandra Pinto graduated in biochemistry from the University of Beira Interior in 2006. During her last year as an undergraduate student she worked at Hospital Cova da Beira where she acquired experience in clinical microbiology. In 2009 she engaged in a PhD in Chemistry at the University of Lisbon and completed it in 2013. A significant portion (regular visits from 2009-2011) of her PhD was carried out at the Weizmann Institute of Science. During her PhD, she acquired strong multidisciplinary training on chemistry, state-of-the-art biophysics methodologies (e.g. Fluorescence Spectroscopy and microscopy) and cell biology which are of great assistance for the characterization of cellular mechanisms related with the action of novel antibiotics. In 2013 she moved to Instituto de Medicina Molecular to pursue a Post-Doctoral experience; there she started studying viral-derived peptides with biomedical interest. In the context of this project and already at IST, she implemented and optimized advanced fluorescence imaging methods, aiming to characterize bacterial biofilm structure during treatment with antimicrobial agents. In the same research line, she and other collaborators have identified novel class of synthetic mimics of AMPs, having a national and international patent applications [Portuguese Patent Nº. 116802, (granted in 21.04.2023). International Patent, Nº. 50030, (filled in 01.10.2021)]. Scientific merit in the past 5 years. In the past 5 years she: - authored and co-authored a total of 54 (34 in last 5 years) ISI-indexed papers - authored and co-authored 35 communications in conferences (16 talks and 19 posters). - was the Principal Investigator of 1 FCT exploratory project (2022.03627.PTDC) which in total amounted to 50.000,00 EUR. - was the co-Principal Investigator of 1 FCT exploratory project (EXPL/BTM-MAT/0910/2021) which in total amounted to 50.000,00 EUR. - was the co-Principal Investigator of the project OSTEOGLUTIS which in total amounted 10.000,00 EUR. This project won the 3rd edition of the Multiple Myeloma Research Fellowship created by the Portuguese Association against Leukemia (APCL) and the Portuguese Society of Hematology (SPH), with the support of Amgen Biopharmaceutical. - Supervised and co-supervised 5 ongoing PhD (2020.05203.BD, UI/BD/151062/2021 2023.03240.BD, 2023.03543.BD and 2023.03193.BD), 9 MSc thesis (8 completed and 1 ongoing) and 8 undergraduate students (3 ongoing). - Was a member of the organizing committee of 2019 and 2023 MicroDia in IST (microscopy Open Day) and the 1st iBB Workshop (Fostering Collaborative Research) and 3rd iBB Workshop. - Participated as guest editor for the journals Frontiers in Cellular and Infection Microbiology topic editor https://www.frontiersin.org/research-topics/60365/exploring-advanced-tools-and-techniques-for-studying-biofilms Pharmaceutics (https://www.mdpi.com/journal/pharmaceutics/special_issues/5FFPG839N7); Antibiotics (https://www.mdpi.com/journal/antibiotics/special_issues/bacterial_biofilm) Molecules (https://www.mdpi.com/journal/molecules/special_issues/nanotherapeutics) and as topic editor for MDPI (https://www.mdpi.com/topics/697178B65N). - Reviewed more than 30 papers for different ISI-indexed journals (https://www.webofscience.com/wos/author/record/1626649). In her Ciência Vitae the most frequent terms used : Chemistry, Biophysics and Biochemistry; Health Sciences - Pharmacology, Pharmacological Sciences and Biomaterials.
Read full resume ↓
Identification

Personal identification

Full name
Sandra Pinto
Date of birth
1983/06/06
Gender
Female

Citation names

  • Pinto, Sandra
  • Pinto, SN

Author identifiers

Ciência ID
DF1B-B557-85AF
ORCID iD
0000-0002-3205-9459
Google Scholar ID
https://scholar.google.pt/citations?user=iR26hMYAAAAJ&hl=pt-PT
Researcher Id
H-8446-2016
Scopus Author Id
25637336300

Email addresses

  • sandrapinto@ist.utl.pt (Professional)

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2009/01 - 2013/06/17
Concluded
 Química (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Finding the biophysical mechanisms underlying the action of Ceramide with distinct N-acyl chain structures: from model to cell membranes" (THESIS/DISSERTATION)
 Pass with Distinction
2001/09 - 2006/09
Concluded
 Bioquímica (Licenciatura)
Universidade da Beira Interior, Portugal
"Contributo para o diagnóstico da infecção pelo citomegalovírus humano: determinação do título de anticorpos neutralizantes e a sua relação com os anticorpos dirigidos contra o domínio AD-1" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2018/11/15 - Current Contracted Researcher (Research) Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2015 - 2018 Postdoc (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/08/01 - 2015/01/28 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2009/06 - 2011/06 Visiting Researcher (Research) Weizmann Institute of Science, Israel
Weizmann Institute of Science, Israel
2007/01 - 2008/12 Researcher (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal

Others

Category
Host institution 		Employer
2009/01 - 2013/06/17 PhD student (Fellowship SFRH/BD/46296/2008) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2005/09 - 2006/09 Undergraduate research project in Biochemistry Centro Hospitalar Cova da Beira EPE, Portugal
Centro Hospitalar Cova da Beira EPE, Portugal
(...)
Projects

Contract

Designation Funders
2023 - Current Next generation of antibiofilm agents: Multivalent dendrimers with antimicrobial and biofilm disruption activity
2022.03627.PTDC
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2023 - Current The role of the plasma membrane in the unconventional secretion of tau: insights into the progression of tauopathies 2022.01454.PTDC
2022.01454.PTDC
Other
Ongoing
2022 - Current SentinelEVs - EXPL/BTM-MAT/0910/2021
EXPL/BTM-MAT/0910/2021
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
2021 - Current Rifabutin liposomes: a novel nanotechnological strategy for effective treatment of systemic methicillin-resistant staphylococcus aureus infections
MMG-2021-092/1-1
Team member
Phospholipid Forschungszentrum e V
Ongoing
2019 - Current Cell penetrating p28 peptide-mediated delivery of nanomedicines for cancer treatment
PTDC/CTM-CER/30034/2017
Team member
Ongoing
2019 - Current Fostering the development of new probiotic approaches for the treatment of candidiasis through the exploration of the Candida actobacilli interference mechanisms
PTDC/BIA-MIC/31515/2017
Team member
Fundação para a Ciência e a Tecnologia
2019 - Current Mini-Hearts: Organoid Engineering for Production of 3D Cardiovascular Microtissues from Human Induced Pluripotent Stem Cells for Cardiotoxicology Assays
PTDC/EMD-TLM/29728/2017
Team member
Fundação para a Ciência e a Tecnologia
Ongoing
2019 - Current Tackling multiple myeloma by osteoblast cross-regulation OSTEOGLUTIS
OSTEOGLUTIS_1018P.05696
Co-Principal Investigator (Co-PI)
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2018 - Current POINT-4-PAC Precision Oncology By Innovative Therapies And Technologies. SAICTPAC/0019/2015 (team member).
SAICTPAC/0019/2015
Team member
Concluded
2014 - 2014 Interaction of bile acids with lipid membranes: creating a shield or bursting the bubble.
info:eu-repo/grantAgreement/FCT/3599-PPCDT/119494/PT
Researcher
Concluded
2013 - 2013 Ceramide-Platforms: implication of membrane biophysical properties on ceramide biological outcome
info:eu-repo/grantAgreement/FCT/3599-PPCDT/124949/PT
Other
Concluded
2009 - 2009 Amyloidogenic proteins: role of lipid-protein interaction in amyloid-like fibril formation.
PTDC/QUI-BIQ/099947/2008
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2008/09 - 2008/12 Lipid Rafts, Ceramide, and Human Immunodeficiency Virus: a Biophysical Connection
info:eu-repo/grantAgreement/FCT/3599-PPCDT/68151/PT
Research Fellow
Concluded
2008/01/01 - 2008/08/01 Molecular interactions in lipid raft models: from lipid phases to membrane protein organization
info:eu-repo/grantAgreement/FCT/3599-PPCDT/82384/PT
Research Fellow
Fundação para a Ciência e a Tecnologia
2007/01/01 - 2007/01 Molecular mechanism of inhibition of the vacuolar H+-ATPase of osteoclasts by potential antiosteporotic drugs
info:eu-repo/grantAgreement/FCT/POCI/57114/PT
Research Fellow
Fundação para a Ciência e a Tecnologia

Other

Designation Funders
2011 - 2014 Relationship between PI(4,5)P2 compartmentalization and palmitoylated synaptic proteins in membrane model systems and in the plasma membrane of neuron and non-neuron like cells
PTDC/QUI-BIQ/112067/2009
Researcher
Concluded
2009 - 2010 Understanding cell membrane lipid domains: from structure, biochemistry and theory to biology
Israel Science Foundation grant number 1735/07
Researcher
Concluded
Outputs

Publications

Conference abstract
  1. Pinto, Sandra; Susana Almeida Dias; Ana F Cruz; Dalila Mil-Homens; Fabio Fernandes; Javier Valle; David Andreu; et al. "Insights into the mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms". Paper presented in Antimicrobial Peptides - Gordon Research Conference, Lucca (Barga), 2019.
  2. Pinto, Sandra; Susana Almeida Dias; Ana F Cruz; Dalila Mil-Homens; Fabio Fernandes; Javier Valle; David Andreu; et al. "Activity of the viral-derived peptide pepR against Staphylococcus aureus biofilms and insights into the mechanism of action". Paper presented in 35 th European Peptide Symposium, Dublin, 2018.
  3. T. Sousa; Pinto, Sandra; S.D. Lucas; R. Moreira; A. Coutinho; R.E. Castro; C.M. Rodrigues; M. Prieto; F. Fernandes. "Interaction of apoptotic and cytoprotective bile acids with biomembranes". Paper presented in 49th Annual meeting of the European Association for the Study of the Liver, London, 2014.
    Published
  4. Pinto, SN; Fábio Fernandes; Anthony H. Futerman; Liana C. Silva; Manuel Prieto. "A combined fluorescence spectroscopy, confocal and 2-photon microscopy approach to re-evaluate the properties of sphingolipid domains". Paper presented in European Biophysics Journal with Biophysics Letters, 2013.
    Published
  5. Pinto, SN; Ana R. Varela; Elad L Laviad; Alfred H. Merrill; Anthony H. Futerman; Manuel Prieto; Liana C Silva. "Ceramide activates endocytosis and forms ordered intracellular lipid domains in response to TNF-alpha". Paper presented in European Biophysics Journal with Biophysics Letters, 2013.
    Published
  6. Ana E. Ventura; Ana R. Varela; Pinto, SN; Amélia M. Silva; Manuel Prieto; Liana C. Silva. "Lipid domain formation and membrane shaping by C24:0-ceramide". Paper presented in European Biophysics Journal with Biophysics Letters, 2013.
  7. Silva, J; Vandermeulen, G; Oliveira, V; Pinto, SN; Graca, L ; Preat, V; Florindo, H. "Dendritic cell-targeted multifunctional vaccine against melanoma using ligand-modified nanoparticles". Paper presented in FEBS Journal, 2013.
    Published
  8. Pinto, SN; Liana C. Silva; Anthony H. Futerman; Manuel Prieto. "The role of ceramide acyl chain length and unsaturation on membrane structure". Paper presented in European Biophysics Journal with Biophysics Letters, 2011.
  9. MJ Sarmento; Pinto, SN; F Fernandes; M Prieto. "Regulation of PIP2 clustering in neuron-like model cells by synaptic protein palmitoylation". Paper presented in Journal with Biophysics Letters, 2011.
  10. Bruno Castro; Pinto, SN; Liana Casquinha da Silva; Manuel José Estevez Prieto. "Rafts and ceramides: biophysical perspective of biologically relevant membrane domains". Paper presented in Chemistry and Physics of Lipids, 2010.
  11. Pinto, SN; Liana Casquinha da Silva; Rodrigo F. M. de Almeida; Manuel José Estevez Prieto. "Ceramide Gel Domain Formation in a Phospholipid Bilayer: The Impact of Ceramide Acyl Chain". Paper presented in Biophysical Journal, 2010.
  12. Pinto, SN; Liana Casquinha da Silva; Rodrigo F. M. de Almeida; Manuel José Estevez Prieto. "Interdigitation, Domains and Morphology, in Membranes of the Chain Asymmetric C24:1 Ceramide". Paper presented in Biophysical Journal, 2009.
    Published
  13. Liana Casquinha da Silva; Bruno Castro; Rodrigo F. M. de Almeida; Pinto, SN; Manuel José Estevez Prieto. "Biophysics of rafts and their interplay with ceramides". Paper presented in Chemistry and Physics of Lipids, 2008.
    Published
  14. Pinto, SN; Liana Casquinha da Silva; ¿Rodrigo F. M. de Almeida¿; Alexander Fedorov; Manuel José Estevez Prieto. "Biophysical behaviour of N-nervonoyl-D-erythro-sphingosine and its interactions with a fluid phospholipid". Paper presented in Chemistry and Physics of Lipids, 2007.
Conference poster
  1. Margarida Marques; Pinto, Sandra; Sofia Santos Costa; SS Costa; S Santos Costa; Henrique Silveira. "Characterization of biofilm formation by bacteria associated with the midgut of Anopheles mosquito, vector of malaria". Paper presented in 3rd iBB Workshop, 2023.
  2. Pereira, Laura; Ana P. Quendera; Andrade, José M.; Marta M. Alves; Vasco D.B. Bonifácio; Pinto, Sandra. "Polycationic Core-shell Dendrimers are potential key players against planktonic and biofilm infections caused by Foodborne Pathogens". Paper presented in X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  3. Condinho, Manuel; Pinto, Sandra; Arraiano, Cecília M.; Pobre, Vânia. "The role of PNPase in the biofilm formation of Escherichia coli". Paper presented in IV International Meeting of Portuguese Society of Genetics, 2023.
  4. Pereira, Laura; Ana P. Quendera; Andrade, José M.; Marta M. Alves; Vasco D.B. Bonifácio; Pinto, Sandra. "Anti-biofilm and Anti-Adhesive effect of polycationic polyurea dendrimers (PURE) against Listeria monocytogenes". Paper presented in I International Meeting Molecules 4Life, 2023.
  5. Condinho, Manuel; Pinto, Sandra; Arraiano, Cecília M.; Pobre, Vânia. "The importance of PNPase biofilm for biofilm formation". Paper presented in EMBO | EMBL Symposium: New approaches and concepts in microbiology, 2023.
  6. Condinho, Manuel; Pinto, Sandra; Arraiano, Cecília M.; Pobre, Vânia. "PNPase, a conserved exoribonuclease fundamental for biofilm formation of Escherichia coli". Paper presented in FEMS2023 | Congress of European Microbiologists, 2023.
  7. Laura Pereira; Ana P. Quendera; José M. Andrade; Marta M. Alves; Vasco D.B. Bonifácio; Sandra N. Pinto. "Combating biofilms of foodborne pathogens with antimicrobial dendrimers". Paper presented in 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2023.
  8. Ricardo M. Silva; Sandra N. Pinto; Vasco D.B. Bonifácio. "Boosting the production of Extracellular Vesicles (EVs) with nitric oxide releasing polyurea biodendrimers". Paper presented in 2nd Meeting of the Portuguese Network on Extracellular Vesicles 2023, 2023.
  9. Diogo Gonçalves; Ricardo Silva; Nuno Bernardes; Ana M. Azevedo; Sandra N. Pinto; Fábio Fernandes. "Analysis of the cytoprotective potential of extracellular vesicles against bacterial pore forming toxins". Paper presented in SNEV 2023 Virtual Conference, 2023.
  10. Ricardo M. Silva; Sandra N. Pinto; Vasco D.B. Bonifácio. "Boosting the production of Extracellular Vesicles (EVs) with nitric oxide releasing polyurea biodendrimers". Paper presented in SNEV 2023 Virtual Conference, 2023.
  11. Laura Pereira; Dalila Mil-Homens; Ana P. Quendera; José M. Andrade; Marta M. Alves; Vasco D.B. Bonifácio; Sandra N. Pinto. "Core–shell Polycationic Polyurea Pharmadendrimers are a Potential alternative to Fight Planktonic and Biofilm infections caused by Foodborne Pathogens". Paper presented in XXVIII Encontro Nacional da SPQ, 2023.
  12. Diogo Gonçalves; Ricardo Silva; Ana M. Azevedo; Sandra N. Pinto; Fábio Fernandes. "Exploring the impact of exosome depletion on Staphylococcus aureus alpha-hemolysin cytotoxic activity". Paper presented in 32nd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2022.
  13. Dalila Mil-Homens; Maria Martins; José Barbosa; Maria João Sarmento; Rita Pires; Vitoria Rodrigues; Vasco D.B. Bonifácio; Pinto, SN. "Therapeutic antimicrobial polymers: the polycationic oligoethyleneimine killing performance against KPC- and OXA-48-producing Klebsiella pneumoniae clinical isolates". Paper presented in 31st European Congress of Clinical Microbiology & Infectious Diseases, 2021.
  14. Dalila Mil-Homens; Maria Martins; José Barbosa; Maria João Sarmento; Rita Pires; Vitoria Rodrigues; Vasco D.B. Bonifácio; Pinto, SN. "Virulence quantification of KPC- and OXA-48-producing Klebsiella pneumoniae isolates in a Galleria mellonella model: Towards a novel therapeutic approach using linear cationic polymers". 2021.
  15. Pinto, SN; Susana A. Dias; Ana F. Cruz; Dalila Mil-Homens; Fabio Fernandes; Javier Valle; David Andreu; et al. "The diffusion of the viral-derived membrane-active peptide pepR along Staphylococcus aureus biofilms causes a graded spatiotemporal profile of bacterial disruption". Paper presented in 1st Open Meeting EuroMicropH, 2020.
  16. Dalila Mil-Homens; Maria Martins; José Barbosa; Maria João Sarmento; Rita Pires; Vitoria Rodrigues; Vasco D.B. Bonifácio; Pinto, SN. "Virulence quantification of KPC- and OXA-48-producing Klebsiella pneumoniae isolates in a Galleria mellonella model: Towards a novel therapeutic approach using linear cationic polymers". Paper presented in MICROBIOTEC´19, 2019.
  17. Ferreira, Magda; Pinto, Sandra; Aires-da-Silva, Frederico; António, Almeida; Aguiar, Sandra I; Bettencourt, Ana; Gaspar, Maria Manuela. "Antibiotic-lipid Based Nanosystems as a Tool for Staphylococcus aureus Associated Bone Infections". Paper presented in 38th Annual Meeting of the European Bone and Joint Infection Society, European Bone and Joint Infection Society (EBJIS), Antwerp, Belgium;, 2019.
  18. Ferreira, Magda; Pinto, Sandra; Ana F Bettencourt; Aguiar, Sandra I; Gaspar, Maria Manuela. "Liposomes as a Tool to Improve Antibacterial Effect of Antibiotics Towards S. aureus Infections". Paper presented in 6th International Symposium on Phospholipids in Pharmaceutical Research – Phospholipid Research Center, Heidelberg, Germany;, 2019.
  19. Dias S.A.; Freire J.M.; Pinto, SN; Cavaco M.; Neves V.; Coutinho A.; Castanho M.A.R.B.; Veiga A.S.. "Studying the antibacterial and antibiofilm activities of the viral-derived peptide vCPP 2319". Paper presented in 9th International Meeting on Antimicrobial Peptides, 2019.
  20. Cruz A.F.; Freire J.M.; Pinto, SN; Coutinho A.; Andreu D.; Castanho M.A.R.B.; Veiga A.S.. "Design and development of short and stable pepR-derived antibacterial peptides". Paper presented in 9th International Meeting on Antimicrobial Peptides, 2019.
  21. Ferreira, Magda; Pinto, Sandra; Ribeiro, I.A.; Aires-da-Silva, Frederico; Almeida, António; Bettencourt, Ana; Aguiar, Sandra I; Gaspar, Maria Manuela. "Antibiotic Liposomal Nanoformulations as a Tool to Inhibit Mature Staphylococcus aureus Biofilms". Paper presented in 11th iMed.ULisboa and 3rd i3du Postgraduate Students Meeting, Faculdade de Farmácia da Universidade de Lisboa (FFUL);, 2019.
  22. Pinto, SN; Susana A. Dias; Ana F. Cruz; Dalila Mil-Homens; Fabio Fernandes; Javier Valle; David Andreu; et al. "Insights into the mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms". Paper presented in 12th European Biophysics Congress and 10th International Conference on Biological Physics, 2019.
  23. Pinto, SN; Dias S.A.; Cruz A.F.; Mil-Homens D.; Fernandes F.; Valle J.; Andreu D.; et al. "Insights into the mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms". Paper presented in 26th American Peptide Symposium, 2019.
  24. Susana A. Dias; Freire J.M.; Pinto, Sandra N; Cavaco M; Neves V; Coutinho A; Castanho M.A. R.B; Veiga A.S. "Studying the antibacterial and antibiofilm activities of the viral-derived peptide vCPP 2319". Paper presented in 9th International Meeting on Antimicrobial Peptides, 2019.
  25. Magda Ferreira; Isabel A. Ribeiro; Pinto, SN; Frederico Aires-da-Silva; António J. Almeida; Sandra I. Aguiar; Ana Bettencourt; Maria M. Gaspar. "Antimicrobial effect of antibiotic-lipid based nanosystems for implant-associated Staphylococcus aureus infection treatment". Paper presented in 2nd SPLC-CRS Young Scientists Meeting, 2019.
  26. Marta M. Alves; Pinto, SN; Catarina Santos; Maria F. Montemor. "The functionalization of ZnO nanostructured coatings in metallic resorbable biomaterials towards personalized medicine". Paper presented in NanoMedicine, 2018.
  27. Pinto, SN; Susana A. Dias; Dalila Mil-Homens; Fábio Fernandes; David Andreu; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Unravelling the antibiofilm mechanism of action of the viral-derived membrane-active peptide pepR". Paper presented in ESCMID/ASM Conference on Drug Development to Meet the Challenge of Antimicrobial Resistance, 2018.
  28. Pinto, SN; Dalila Mil-Homens; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Studying the antibiofilm properties of the peptide pepR using a biophysical approach". Paper presented in Biofilms 8, 2018.
  29. Cruz A.F.; Pinto, SN; Freire J.M.; Coutinho A.; Andreu D.; Castanho M.A.R.B.; Veiga A.S.. "Searching for short and effective antimicrobial peptides against Staphylococcus aureus biofilms". Paper presented in 16th Iberian Peptide Meeting, 2018.
  30. Pinto, SN; Susana A. Dias; Dalila Mil-Homens; Fábio Fernandes; David Andreu ; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Unravelling the antibiofilm mechanism of action of the antimicrobial peptide pepR". Paper presented in MICROBIOTEC'17, 2017.
  31. Susana Barahona; Dalila Mil-Homens; Inês J Silva; Ricardo N Moreira; Pinto, SN; Arsénio M Fialho; Cecília M Arraiano. "New insights into Salmonella Typhimurium virulence". Paper presented in MICROBIOTEC'17, 2017.
  32. Cláudia P. Godinho; Catarina S. Prata; Nuno P. Mira; Pinto, SN; Fábio Fernandes; Isabel Sá-Correia. "The ABC transporter Pdr18 and ergosterol homeostasis are involved in yeast response and tolerance to acetic acid by counteracting stress-induced decrease of plasma membrane order". Paper presented in PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi, 2016.
  33. Pinto, SN; Dalila Mil-Homens; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Application of Image-based confocal microscopy and standardized laboratory techniques to study the effect of antimicrobial agents within bacterial biofilms". Paper presented in IN workshop, 2016.
  34. Pinto, SN; Dalila Mil-Homens; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Investigating the relationship between antimicrobial agents mechanisms of action and anti-biofilm activity using confocal microscopy techniques". Paper presented in Biofilms7, 2016.
  35. Pinto, SN; Ana E Ventura; Ana RP Varela; Anthony H Futerman; Manuel Prieto; Liana C. Silva. "Ceramide-gel domains in living cells: understanding the role of membrane biophysical properties in cell (patho)physiology". Paper presented in Gordon Research Conference – Glycolipids and Sphingolipids Biology, 2016.
  36. Tânia Sousa; Rui E. Castro; Pinto, SN; Ana Coutinho; Susana D. Lucas; Rui Moreira; Cecília M.P. Rodrigues; Manuel Prieto; Fábio Fernandes. "Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties". Paper presented in 5th International Iberian Biophysics Congress,, 2016.
  37. Pinto, SN; Dalila Mil-Homens; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Investigating the relationship between antimicrobial agents mechanisms of action and anti-biofilm activity using confocal microscopy techniques". 2016.
  38. Pinto, SN; Dalila Mil-Homens; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Studying the relationship between diffusion of antimicrobial agents within bacterial biofilms and anti-biofilm activity using confocal microscopy techniques". Paper presented in MicroBiotec15, 2015.
  39. A.I. Meleiro; Pinto, SN; G.A. Monteiro; F. Fernandes. "Reverse lipofection for spatially defined transfection with DNA/cationic lipoplexes". Paper presented in MicroBiotec15, 2015.
  40. Pinto, SN; Dalila Mil-Homens; Miguel A.R.B Castanho; Manuel Prieto; Ana Coutinho; Ana Salomé Veiga. "Confocal microscopy tools applied to the study of antimicrobial agents diffusion into bacterial biofilms". Paper presented in 3rd IMM Postdoc Day, 2015.
  41. Pinto, SN; Elad L Laviad; Johnny Stiban; Samuel L Kelly; Alfred H Merrill Jr; Manuel Prieto; Anthony H Futerman; Liana C Silva. "Effect of ceramide-acyl chain structure on the biophysical properties of living cells". Paper presented in International Ceramide Conference, 2015.
  42. Ana E Ventura; Pinto, SN; Ana RP Varela; Anthony H Futerman; Manuel Prieto; Liana C. Silva. "Activation of TNF receptor leads to ceramide-gel domain formation in endocytic vesicles". Paper presented in WE- Heraeus Seminar: Advanced Microscopy of Membrane Biophysics, 2015.
  43. Tânia Sousa; Rui E. Castro; Pinto, SN; Ana Coutinho; Susana D. Lucas; Rui Moreira; Cecília M.P. Rodrigues; Manuel Prieto; Fábio Fernandes. "The cytotoxic bile acid DCA modulates apoptotic signalling through alteration of mitochondrial membrane properties". Paper presented in 59th Biophysical Society Annual Meetin, 2015.
  44. Tânia Sousa; Pinto, SN; Susana D. Lucas; Rui Moreira; Ana Coutinho; Rui E. Castro; Cecília M. P. Rodrigues; Manuel Prieto; Fábio Fernandes. "Interaction of apoptotic and cytoprotective bile acids with biomembranes". Paper presented in International Liver Congress TM, 49th Annual Meeting of the European Association for the Study of the Liver (EASL), 2014.
  45. T. Sousa; A. Coutinho; R. E. Castro; S. D. Lucas; R. Moreira; C. M. P. Rodrigues; Pinto, SN; M. Prieto; F. Fernandes. "The cytotoxic bile acid DCA is able to change apoptotic signalling through modulation of mitochondrial membrane properties". Paper presented in Pychem, 2014.
  46. T. Sousa; A. Coutinho; R. E. Castro; S. D. Lucas; R. Moreira; C. M. P. Rodrigues; Pinto, SN; M. Prieto; F. Fernandes. "The cytotoxic bile acid DCA modulates apoptotic signalling through alteration of mitochondrial membrane properties". Paper presented in FEBS/Biochemical Society Focused Meeting, 2014.
  47. Ana E. Ventura; Ana. R. Varela; Andreia G. Santos; Pinto, SN; Anthony H. Furterman; Manuel Prieto; Liana C. Silva. "Characterization of ceramide-induced changes on the biophysical properties of cellular membranes". Paper presented in Symposium Sphingolipids in Health and Disease, 2014.
  48. Pinto, SN; Fábio Fernandes; Anthony H. Futerman; Liana C. Silva; Manuel Prieto. "A combined fluorescence spectroscopy, confocal and 2-photon microscopy approach to re-evaluate the properties of sphingolipid domains". Paper presented in The 9th EBSA European Biophysics Congress, 2013.
  49. Pinto, SN; Ana R. Varela; Elad L Laviad; Alfred H. Merrill; Anthony H. Futerman; Manuel Prieto; Liana C Silva. "Ceramide activates endocytosis and forms ordered intracellular lipid domains in response to TNF-alpha". Paper presented in The 9th EBSA European Biophysics Congress, Lisbon, 2013.
  50. Ana E. Ventura; Ana R. Varela; Pinto, SN; Amélia M. Silva; Manuel Prieto; Liana C. Silva. "Lipid domain formation and membrane shaping by C24:0-ceramide". Paper presented in The 9th EBSA European Biophysics Congress, 2013.
  51. Joana Silva; Gaelle Vandermeulen; V. Oliveira; L. Graça; Pinto, SN; Véronique Préat; Helena Florindo. "Dendritic cell-targeted multifunctional vaccine against melanoma using ligand-modified nanoparticles". Paper presented in 38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), 2013.
  52. Joana Silva; Gaelle Vandermeulen; V. Oliveira; Pinto, SN; Mafalda Videira; Véronique Préat; Helena Florindo. "Development of dendritic-cell targeted peptide vaccine against melanoma by ligand-modified nanoparticles". Paper presented in 40th Annual Meeting and Exposition of the controlled released society, 2013.
  53. Pinto, SN; Elad Laviad; Manuel Prieto; Anthony H. Futerman; Liana C. Silva. "Ceramide-induced domains on the cell membrane of live cells". Paper presented in EMBO Workshop of Molecular Medicine on Sphingolipids, 2012.
  54. Joana Silva; Pinto, SN; Gaelle Vandermeulen; Mafalda Videira; Helena Florindo; Véronique Préat. "Development of dendritic-cell targeted peptide vaccine against melanoma by ligand-modified nanoparticles". Paper presented in EMBO Workshop of Molecular Medicine on Sphingolipids, 2012.
  55. Ermelinda M. S Maçôas; Gema Marcelo; Pinto, SN; Tatiana Cañeque; Ana M Cuadro; Juan J Vaquero; José M. G. Martinho. "In the quest for nonlinear absorbing dyes for bioimaging". Paper presented in Vth International Congress on Molecular Materials, 2012.
  56. Pinto, SN; Elad Laviad; Anthony H. Futerman; Manuel Prieto; Liana C. Silva. "Effect of sphingolipid acyl chain structure and ceramide generation in the biophysical properties of living cells". Paper presented in Gordon Research Conferences (Glycolipids and Sphingolipid Biology), 2012.
  57. Pinto, SN; Liana C. Silva; Anthony H. Futerman; Manuel Prieto. "Ceramide membrane biophysics: the role of acyl chain length and unsaturation". Paper presented in The 17th IUPAB International Biophysics Congress, 2011.
  58. Pinto, SN; Liana C. Silva; Anthony H. Futerman; Manuel Prieto. "The role of ceramide acyl chain length and unsaturation on membrane structure". Paper presented in The 8th EBSA European Biophysics Congress, 2011.
  59. Sarmento, Maria J.; Pinto, SN; FERNANDES, FABIO; Manuel José Estevez Prieto. "Regulation of PIP2 clustering in neuron-like model cells by synaptic protein palmitoylation". Paper presented in The 8th EBSA European Biophysics Congress, 2011.
  60. Ermelinda M. S. Maçôas; Tatiana Cañeque; Gema Marcelo; José M. G Martinho; Juan J. Vaquero; Pinto, SN; Sucunza, D. "Cationic Chromophores with two-photon absorption for application in bioimaging". Paper presented in XXXIII Bienal de la RSEQ, 2011.
  61. Ermelinda M. S. Maçôas; Pinto, SN; Tatiana Cañeque; Gema Marcelo. "Two photon absorption chromophores based on quinolizinium cation". Paper presented in Symposium ESOC 2011, 2011.
  62. Pinto, SN; Liana Casquinha da Silva; ¿Rodrigo F. M. de Almeida¿; Manuel José Estevez Prieto. "Laurdan Fluorescence Generalized Polarization and anisotropy applied to the study of high-order membrane microdomains". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  63. Pinto, SN; Liana Casquinha da Silva; ¿Rodrigo F. M. de Almeida¿; Manuel José Estevez Prieto. "Ceramide Gel Domain Formation in a Phospholipid Bilayer: The Impact of Ceramide Acyl Chain". Paper presented in International Student Workshop on Lipid Domains, 2010.
  64. Pinto, SN; Liana Casquinha da Silva; ¿Rodrigo F. M. de Almeida¿; Manuel José Estevez Prieto. "Ceramide Gel Domain Formation in a Phospholipid Bilayer: The Impact of Ceramide Acyl Chain". Paper presented in 54th Biophysical Society Annual Meeting, 2010.
  65. Rocio Esquembre; Pinto, SN; José António Poveda; Manuel José Estevez Prieto; Reyes Mateo. "Immobilization of liposomes in a sol-gel matrix: a fluorescence confocal microscopy study". Paper presented in European Biophysics Congress, 2009.
  66. Pinto, SN; Liana Casquinha da Silva; ¿Rodrigo F. M. de Almeida¿; Manuel José Estevez Prieto. "The impact of N-acyl chain on the properties of gel domains formed by the Signalling Lipid Ceramide". Paper presented in 5th International Charleston Ceramide Conference, 2009.
  67. Pinto, SN; Liana Casquinha da Silva; Rodrigo F. M. de Almeida; Manuel José Estevez Prieto. "Interdigitation, Domains and Morphology, in Membranes of the Chain Asymmetric C24:1 Ceramide". Paper presented in 53rd Biophysical Society Annual Meeting, 2009.
  68. Pinto, SN; Liana Casquinha da Silva; ¿Rodrigo F. M. de Almeida¿; Manuel José Estevez Prieto. "Characterization of membrane behaviour of the asymmetric ceramide (C24:1 Cer)". Paper presented in 1st Portuguese-Spanish-British Biophysics Congress, 2008.
  69. Pinto, SN; Liana Casquinha da Silva; Rodrigo F. M. de Almeida; Alexander Fedorov; Manuel José Estevez Prieto. "Biophysical behaviour of N-nervonoyl-D-erythro-sphingosine and its interactions with a fluid phospholipid". Paper presented in 48th International Conference on Bioscience of Lipids, 2007.
Journal article
  1. Hélio L. Barros; Margarida Espadinha; Sandra N. Pinto; Ricardo J.F. Ferreira; Joana B. Loureiro; Rita Silva; Lucília Saraiva; Ermelinda Maçôas; Maria M.M. Santos. "Tryptophanol-derived oxazoloisoindolinone fluorescent probes for cellular localization studies of p53 activators". Bioorganic Chemistry (2024): http://dx.doi.org/10.1016/j.bioorg.2024.107898.
    10.1016/j.bioorg.2024.107898
  2. Ana Marta Diniz; Carina I. C. Crucho; Maria J. Ruedas-Rama; Angel Orte; Cristina J. Dias; Mani Outis; Sandra N. Pinto; et al. "TADF-Emitting Nanoparticles for Application as Probes in Time-Resolved Imaging and 1O2 Photosensitizers". Advanced Optical Materials (2024): https://doi.org/10.1002/adom.202402063.
    10.1002/adom.202402063
  3. Arévalo-Cid, Pablo; Cruz, Adriana; Pinto, Sandra N.; Montemor, M.F.; Alves, Marta M.. "Cerium-oxide functionalized iron scaffolds: A synergistic approach for enhanced degradation and reduced cytotoxicity". Materials Today Chemistry 38 (2024): 102108. http://dx.doi.org/10.1016/j.mtchem.2024.102108.
    10.1016/j.mtchem.2024.102108
  4. Gonçalves, Joana; Amaral, Joana D.; Capela, Rita; Perry, Maria de Jesus; Braga, Cláudia; Gaspar, Maria Manuela; Piedade, Fátima M.; et al. "Necroptosis induced by ruthenium (II) complexes as mitochondrial disruptors". Cell Death Discovery 10 1 (2024): http://dx.doi.org/10.1038/s41420-024-02033-z.
    10.1038/s41420-024-02033-z
  5. Pinho, Jacinta O.; Ferreira, Magda; Coelho, Mariana; Pinto, Sandra N.; Aguiar, Sandra I.; Gaspar, Maria Manuela. "Liposomal Rifabutin—A Promising Antibiotic Repurposing Strategy against Methicillin-Resistant Staphylococcus aureus Infections". Pharmaceuticals 17 4 (2024): 470. http://dx.doi.org/10.3390/ph17040470.
    10.3390/ph17040470
  6. Susana A. Dias; Sandra N. Pinto; Ana S. Silva-Herdade; Marco Cavaco; Vera Neves; Luís Tavares; Manuela Oliveira; et al. "Quantitative Imaging of the Action of vCPP2319, an Antimicrobial Peptide from a Viral Scaffold, against Staphylococcus aureus Biofilms of a Clinical Isolate". ACS Infectious Diseases (2023): https://doi.org/10.1021/acsinfecdis.3c00195.
    10.1021/acsinfecdis.3c00195
  7. Santos, Carla I.M.; Santiago, Ana M.; Araújo, Ana R.L.; Pinto, Sandra; Agostinho, Rafaela R.; Simão, Sónia; Azevedo, Tomás P.; et al. "New fluorescent probes based on gallium(III) corrole complexes for the recognition of hydrogen sulfide: A journey from solution to intracellular site". Dyes and Pigments 216 (2023): 111304. http://dx.doi.org/10.1016/j.dyepig.2023.111304.
    10.1016/j.dyepig.2023.111304
  8. Casteleiro, Bárbara; Da Cruz-Boisson, Fernande; Alcouffe, Pierre; Pinto, Sandra N.; Gaspar Martinho, José M.; Charreyre, Marie-Thérèse; Farinha, José Paulo Sequeira; Favier, Arnaud. "Near-Infrared-Luminescent Gold Nanoclusters Stabilized by End-Grafted Biocompatible Polymer Chains for Bioimaging". ACS Applied Nano Materials (2023): http://dx.doi.org/10.1021/acsanm.3c01665.
    10.1021/acsanm.3c01665
  9. Gonçalves, Diogo; Pinto, Sandra N.; Fernandes, Fábio. "Extracellular Vesicles and Infection: From Hijacked Machinery to Therapeutic Tools". Pharmaceutics 15 6 (2023): 1738. http://dx.doi.org/10.3390/pharmaceutics15061738.
    10.3390/pharmaceutics15061738
  10. Quendera, Ana Patrícia; Pinto, Sandra Nunes; Pobre, Vânia; Antunes, Wilson; Bonifácio, Vasco D. B.; Arraiano, Cecília Maria; Andrade, José Marques. "The ribonuclease PNPase is a key regulator of biofilm formation in Listeria monocytogenes and affects invasion of host cells". npj Biofilms and Microbiomes 9 1 (2023): http://dx.doi.org/10.1038/s41522-023-00397-1.
    10.1038/s41522-023-00397-1
  11. Pedro, Nuno A.; Fontebasso, Gabriela; Pinto, Sandra N.; Alves, Marta; Mira, Nuno P.. "Acetate modulates the inhibitory effect of Lactobacillus gasseri against the pathogenic yeasts Candida albicans and Candida glabrata". Microbial Cell 10 4 (2023): 88-102. http://dx.doi.org/10.15698/mic2023.04.795.
    10.15698/mic2023.04.795
  12. Cruz, Adriana; Barbosa, José; Antunes, Patrícia; Bonifácio, Vasco D. B.; Pinto, Sandra N.. "A Glimpse into Dendrimers Integration in Cancer Imaging and Theranostics". International Journal of Molecular Sciences 24 6 (2023): 5430. http://dx.doi.org/10.3390/ijms24065430.
    10.3390/ijms24065430
  13. Dias, Tiago P.; Pinto, Sandra N.; Carvalho, Sandra; Fernandes, Tiago G.; Fernandes, Fábio; Diogo, Maria Margarida; Peleteiro, Maria C.; Prieto, Manuel; Cabral, Joaquim M. S.. "Cost-Effective Mechanical Aggregation of Cardiac Progenitors and Encapsulation in Matrigel Support Self-Organization in a Dynamic Culture Environment". International Journal of Molecular Sciences 23 24 (2022): 15785. http://dx.doi.org/10.3390/ijms232415785.
    10.3390/ijms232415785
  14. Raj, Ritu; Pinto, Sandra N.; Crucho, Carina I.C.; Das, Surajit; Baleizão, Carlos; Farinha, José Paulo S.. "Optically traceable PLGA-silica nanoparticles for cell-triggered doxorubicin delivery". Colloids and Surfaces B: Biointerfaces 220 (2022): 112872. http://dx.doi.org/10.1016/j.colsurfb.2022.112872.
    10.1016/j.colsurfb.2022.112872
  15. Tiago P. Dias; Tânia Baltazar; Sandra N. Pinto; Tiago G. Fernandes; Fábio Fernandes; Maria Margarida Diogo; Manuel Prieto; Joaquim M. S. Cabral. "Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs". Stem Cells International (2022): https://doi.org/10.1155/2022/4542719.
    10.1155/2022/4542719
  16. Bexiga, Nuno M.; Alves, Marta M.; Taryba, Maryna G.; Pinto, Sandra N.; Montemor, M.F.. "Early biomimetic degradation of Mg-2Ca alloy reveals the impact of ß-phases at the interface of this biomaterial on a micro-scale level". Corrosion Science 207 (2022): 110526. http://dx.doi.org/10.1016/j.corsci.2022.110526.
    10.1016/j.corsci.2022.110526
  17. Dias, Susana A; Pinto, Sandra N; Silva-Herdade, Ana S; Cheneval, Olivier; Craik, David J; Coutinho, Ana; Castanho, Miguel A R B; Henriques, Sónia T; Veiga, Ana Salomé. "A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms". Journal of Antimicrobial Chemotherapy (2022): http://dx.doi.org/10.1093/jac/dkac309.
    10.1093/jac/dkac309
  18. Condinho, Manuel; Carvalho, Beatriz; Cruz, Adriana; Pinto, Sandra N.; Arraiano, Cecília M.; Pobre, Vânia. "The role of RNA regulators, quorum sensing and c-di-GMP in bacterial biofilm formation". FEBS Open Bio (2022): http://dx.doi.org/10.1002/2211-5463.13389.
    10.1002/2211-5463.13389
  19. Barbosa, Mariana; Simões, Hélvio; Pinto, Sandra N.; Macedo, Ana S.; Fonte, Pedro; Prazeres, D.Miguel F.. "Fusions of a Carbohydrate Binding Module with the Small Cationic Hexapeptide RWRWRW Confer Antimicrobial Properties to Cellulose-based Materials". Acta Biomaterialia (2022): http://dx.doi.org/10.1016/j.actbio.2022.02.042.
    10.1016/j.actbio.2022.02.042
  20. Antunes, Patrícia; Cruz, Adriana; Barbosa, José; Bonifácio, Vasco D. B.; Pinto, Sandra N.. "Lipid Droplets in Cancer: From Composition and Role to Imaging and Therapeutics". Molecules 27 3 (2022): 991. http://dx.doi.org/10.3390/molecules27030991.
    10.3390/molecules27030991
  21. Bárria, Cátia; Mil-Homens, Dalila; Pinto, Sandra N.; Fialho, Arsénio M.; Arraiano, Cecília M.; Domingues, Susana. "RNase R, a New Virulence Determinant of Streptococcus pneumoniae". Microorganisms 10 2 (2022): 317. http://dx.doi.org/10.3390/microorganisms10020317.
    10.3390/microorganisms10020317
  22. Mariama Djaló; Maria J. S. A. Silva; Hélio Faustino; Sandra N. Pinto; Ricardo Mendonça; Pedro M. P. Gois. "Multivalent NHS-activated acrylates for orthogonal site-selective functionalisation of peptides at cysteine residues". Chemical Communications (2022): https://doi.org/10.1039/D2CC02204D.
    10.1039/D2CC02204D
  23. Pinto, Sandra N.; Mil-Homens, Dalila; Pires, Rita F.; Alves, Marta M.; Serafim, Gabriel; Martinho, Nuno; Melo, Manuel; Fialho, Arsénio M.; Bonifácio, Vasco D. B.. "Core-shell polycationic polyurea pharmadendrimers: new-generation of sustainable broad-spectrum antibiotics and antifungals". Biomaterials Science 10 18 (2022): 5197-5207. http://dx.doi.org/10.1039/d2bm00679k.
    10.1039/d2bm00679k
  24. Baldo, Silvia; Antunes, Patrícia; Felicidade, João Falcão; Santos, Fábio M. F.; Arteaga, Jesús F.; Fernandes, Fábio; Pischel, Uwe; Pinto, Sandra N.; Gois, Pedro M. P.. "The BASHY Platform Enables the Assembly of a Fluorescent Bortezomib–GV1001 Conjugate". ACS Medicinal Chemistry Letters 13 1 (2021): 128-133. http://dx.doi.org/10.1021/acsmedchemlett.1c00615.
    10.1021/acsmedchemlett.1c00615
  25. Adriana Cruz; Manuel Condinho; Beatriz Carvalho; Cecília M. Arraiano; Vânia Pobre; Sandra N. Pinto. "The Two Weapons against Bacterial Biofilms: Detection and Treatment". Antibiotics (2021): https://doi.org/10.3390/antibiotics10121482.
    10.3390/antibiotics10121482
  26. Inês F. A. Mariz; Sandra N. Pinto; Ana M. Santiago; José M. G. Martinho; Javier Recio; Juan J. Vaquero; Ana M. Cuadro; Ermelinda Maçôas. "Two-photon activated precision molecular photosensitizer targeting mitochondria". Communications Chemistry (2021): https://doi.org/10.1038/s42004-021-00581-4.
    10.1038/s42004-021-00581-4
  27. Maria J. Sarmento; Luís Borges-Araújo; Sandra N. Pinto; Nuno Bernardes; Joana C. Ricardo; Ana Coutinho; Manuel Prieto; Fábio Fernandes. "Quantitative FRET Microscopy Reveals a Crucial Role of Cytoskeleton in Promoting PI(4,5)P2 Confinement". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms222111727.
    10.3390/ijms222111727
  28. Ana Rita Garizo; Lígia F. Coelho; Sandra Pinto; Tiago P. Dias; Fábio Fernandes; Nuno Bernardes; Arsénio M. Fialho. "The Azurin-Derived Peptide CT-p19LC Exhibits Membrane-Active Properties and Induces Cancer Cell Death". Biomedicines 9 9 (2021): 1194-1194. https://doi.org/10.3390/biomedicines9091194.
    10.3390/biomedicines9091194
  29. Magda Ferreira; Sandra N. Pinto; Frederico Aires-da-Silva; Ana Bettencourt; Sandra I. Aguiar; Maria Manuela Gaspar. "Liposomes as a Nanoplatform to Improve the Delivery of Antibiotics into Staphylococcus aureus Biofilms". Pharmaceutics (2021): https://doi.org/10.3390/pharmaceutics13030321.
    10.3390/pharmaceutics13030321
  30. Dalila Mil-Homens; Maria Martins; José Barbosa; Gabriel Serafim; Maria J. Sarmento; Rita F. Pires; Vitória Rodrigues; Vasco D.B. Bonifácio; Sandra N. Pinto. "Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates: In Vivo Virulence Assessment in Galleria mellonella and Potential Therapeutics by Polycationic Oligoethyleneimine". Antibiotics 10 1 (2021): 56-56. https://doi.org/10.3390/antibiotics10010056.
    10.3390/antibiotics10010056
  31. Pimenta, Andreia I.; Mil-Homens, Dalila; Pinto, Sandra N.; Fialho, Arsenio M.. "Phenotypic characterization of trimeric autotransporter adhesin-defective bcaC mutant of Burkholderia cenocepacia: cross-talk towards the histidine kinase BCAM0218". Microbes and Infection 22 9 (2020): 457-466. http://dx.doi.org/10.1016/j.micinf.2020.05.018.
    10.1016/j.micinf.2020.05.018
  32. Santos, Carla I.M.; Rodríguez-Pérez, Laura; Gonçalves, Gil; Pinto, Sandra N.; Melle-Franco, Manuel; Marques, Paula A.A.P.; Faustino, M. Amparo F.; et al. "Novel hybrids based on graphene quantum dots covalently linked to glycol corroles for multiphoton bioimaging". Carbon 166 (2020): 164-174. http://dx.doi.org/10.1016/j.carbon.2020.04.012.
    10.1016/j.carbon.2020.04.012
  33. Milheiro, Sofia A.; Gonçalves, Joana; Lopes, Ricardo M. R. M.; Madureira, Margarida; Lobo, Lis; Lopes, Andreia; Nogueira, Fátima; et al. "Half-Sandwich Cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype". Inorganic Chemistry 59 17 (2020): 12722-12732. http://dx.doi.org/10.1021/acs.inorgchem.0c01795.
    10.1021/acs.inorgchem.0c01795
  34. Alves, Marta M.; Mil-Homens, Dalila; Pinto, Sandra; Santos, Catarina F.; Montemor, M.F.. "Antagonist biocompatibilities of Zn-based materials functionalized with physiological active metal oxides". Colloids and Surfaces B: Biointerfaces 191 (2020): 110990. http://dx.doi.org/10.1016/j.colsurfb.2020.110990.
    10.1016/j.colsurfb.2020.110990
  35. Crucho, Carina I. C.; Avó, João; Diniz, Ana M.; Pinto, Sandra N.; Barbosa, José; Smith, Poppy O.; Berberan-Santos, Mário Nuno; Pålsson, Lars-Olof; Dias, Fernando B.. "TADF Dye-Loaded Nanoparticles for Fluorescence Live-Cell Imaging". Frontiers in Chemistry 8 (2020): http://dx.doi.org/10.3389/fchem.2020.00404.
    10.3389/fchem.2020.00404
  36. Carina I.C. Crucho; João Avó; Roberto Nobuyasu; Sandra N. Pinto; Fábio Fernandes; João C. Lima; Mário N. Berberan-Santos; Fernando B. Dias. "Silica nanoparticles with thermally activated delayed fluorescence for live cell imaging". Materials Science and Engineering: C 109 (2020): 110528-110528. https://doi.org/10.1016%2Fj.msec.2019.110528.
    10.1016/j.msec.2019.110528
  37. Pinto, Sandra N; Dias, Susana A; Cruz, Ana F; Mil-Homens, Dalila; Fernandes, Fabio; Valle, Javier; Andreu, David; et al. "The mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms". Journal of Antimicrobial Chemotherapy 74 9 (2019): 2617-2625. http://dx.doi.org/10.1093/jac/dkz223.
    10.1093/jac/dkz223
  38. Cavalheiro M; Costa C; Silva-Dias A; Miranda IM; Wang C; Pais P; Pinto SN; et al. "A Transcriptomics Approach To Unveiling the Mechanisms of In Vitro Evolution towards Fluconazole Resistance of a Candida glabrata Clinical Isolate.". Antimicrobial agents and chemotherapy (2018): http://europepmc.org/abstract/med/30348666.
    10.1128/aac.00995-18
  39. Nuno Bernardes; Ana Rita Garizo; Sandra N. Pinto; Bernardo Caniço; Catarina Perdigão; Fábio Fernandes; Arsenio M. Fialho. "Azurin interaction with the lipid raft components ganglioside GM-1 and caveolin-1 increases membrane fluidity and sensitivity to anti-cancer drugs". Cell Cycle 17 13 (2018): 1649-1666. https://doi.org/10.1080/15384101.2018.1489178.
    10.1080/15384101.2018.1489178
  40. Miranda CC; Fernandes TG; Pinto SN; Prieto M; Diogo MM; Cabral JMS. "A scale Out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies.". Toxicology letters (2018): http://europepmc.org/abstract/med/29775723.
    10.1016/j.toxlet.2018.05.018
  41. Godinho CP; Prata CS; Pinto SN; Cardoso C; Bandarra NM; Fernandes F; Sá-Correia I. "Pdr18 is involved in yeast response to acetic acid stress counteracting the decrease of plasma membrane ergosterol content and order.". Scientific reports (2018): http://europepmc.org/abstract/med/29777118.
    10.1038/s41598-018-26128-7
  42. Dias TP; Pinto SN; Santos JI; Fernandes TG; Fernandes F; Diogo MM; Prieto M; Cabral JMS. "Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture.". Biochemical and biophysical research communications (2018): http://europepmc.org/abstract/med/29601816.
    10.1016/j.bbrc.2018.03.198
  43. Dalila Mil-Homens; Susana Barahona; Ricardo N. Moreira; Inês J Silva; Sandra N. Pinto; Arsénio M. Fialho; Cecília M. Arraiano. "The stress-response protein BolA influences fitness and promotes Salmonella Typhimurium virulence". Applied and Environmental Microbiology (2018): AEM.02850-17. https://doi.org/10.1128%2Faem.02850-17.
    10.1128/aem.02850-17
  44. Carla I. M. Santos; Inês F. A. Mariz; Sandra N. Pinto; Gil Gonçalves; Igor Bdikin; Paula A. A. P. Marques; Maria Graça P. M. S. Neves; José M. G. Martinho; Ermelinda M. S. Maçôas. "Selective two-photon absorption in carbon dots: a piece of the photoluminescence emission puzzle". Nanoscale 10 26 (2018): 12505-12514. https://doi.org/10.1039/C8NR03365J.
    10.1039/C8NR03365J
  45. Mil-Homens D; Pinto SN; Matos RG; Arraiano C; Fialho AM. "Burkholderia cenocepacia K56-2 trimeric autotransporter adhesin BcaA binds TNFR1 and contributes to induce airway inflammation.". (2017): http://europepmc.org/abstract/med/27684048.
    10.1111/cmi.12677
  46. Mariz IFA; Pinto S; Lavrado J; Paulo A; Martinho JMG; Maçôas EMS. "Cryptolepine and quindoline: understanding their photophysics.". (2017): http://europepmc.org/abstract/med/28265616.
    10.1039/c7cp00455a
  47. Sarmento, M.J.; Pinto, S.N.; Coutinho, A.; Prieto, M.; Fernandes, F.. "Accurate quantification of inter-domain partition coefficients in GUVs exhibiting lipid phase coexistence". RSC Advances 6 71 (2016): 66641-66649. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979587338&partnerID=MN8TOARS.
    10.1039/c6ra13170k
  48. Marcelo G; Pinto S; Cañeque T; Mariz IF; Cuadro AM; Vaquero JJ; Martinho JM; Maçôas EM. "Nonlinear emission of quinolizinium-based dyes with application in fluorescence lifetime imaging.". (2015): http://europepmc.org/abstract/med/25135761.
    10.1021/jp507095b
  49. Sousa, T.; Castro, R.E.; Pinto, S.N.; Coutinho, A.; Lucas, S.D.; Moreira, R.; Rodrigues, C.M.P.; Prieto, M.; Fernandes, F.. "Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties". Journal of Lipid Research 56 11 (2015): 2158-2171. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948844490&partnerID=MN8TOARS.
    10.1194/jlr.M062653
  50. Silva JM; Vandermeulen G; Oliveira VG; Pinto SN; Rodrigues C; Salgado A; Afonso CA; et al. "Development of functionalized nanoparticles for vaccine delivery to dendritic cells: a mechanistic approach.". (2014): http://europepmc.org/abstract/med/25529568.
    10.2217/nnm.14.135
  51. Mil-Homens D; Leça MI; Fernandes F; Pinto SN; Fialho AM. "Characterization of BCAM0224, a multifunctional trimeric autotransporter from the human pathogen Burkholderia cenocepacia.". (2014): http://europepmc.org/abstract/med/24659767.
    10.1128/JB.00061-14
  52. Pinto SN; Laviad EL; Stiban J; Kelly SL; Merrill AH Jr; Prieto M; Futerman AH; Silva LC. "Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain.". (2013): http://europepmc.org/abstract/med/24163422.
    10.1194/jlr.M042002
  53. Pinto, S.N.; Fernandes, F.; Fedorov, A.; Futerman, A.H.; Silva, L.C.; Prieto, M.. "A combined fluorescence spectroscopy, confocal and 2-photon microscopy approach to re-evaluate the properties of sphingolipid domains". Biochimica et Biophysica Acta - Biomembranes 1828 9 (2013): 2099-2110. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879228705&partnerID=MN8TOARS.
    10.1016/j.bbamem.2013.05.011
  54. Esquembre, R.; Pinto, S.N.; Poveda, J.A.; Prieto, M.; Mateo, C.R.. "Immobilization and characterization of giant unilamellar vesicles (GUVs) within porous silica glasses". Soft Matter 8 2 (2012): 408-417. http://www.scopus.com/inward/record.url?eid=2-s2.0-83455168947&partnerID=MN8TOARS.
    10.1039/c1sm06264f
  55. Pinto, S.N.; Silva, L.C.; Futerman, A.H.; Prieto, M.. "Effect of ceramide structure on membrane biophysical properties: The role of acyl chain length and unsaturation". Biochimica et Biophysica Acta - Biomembranes 1808 11 (2011): 2753-2760. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052265605&partnerID=MN8TOARS.
    10.1016/j.bbamem.2011.07.023
  56. Maôas, E.; Marcelo, G.; Pinto, S.; Cañeque, T.; Cuadro, A.M.; Vaquero, J.J.; Martinho, J.M.G.. "A V-shaped cationic dye for nonlinear optical bioimaging". Chemical Communications 47 26 (2011): 7374-7376. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959410419&partnerID=MN8TOARS.
    10.1039/c1cc12163d
  57. Pinto, S.N.; Silva, L.C.; De Almeida, R.F.M.; Prieto, M.. "Membrane domain formation, interdigitation, and morphological alterations induced by the very long chain asymmetric C24:1 ceramide". Biophysical Journal 95 6 (2008): 2867-2879. http://www.scopus.com/inward/record.url?eid=2-s2.0-55549135378&partnerID=MN8TOARS.
    10.1529/biophysj.108.129858

Intellectual property

Patent
  1. Pinto, SN; Mil-Homens, Dalila; Nuno Bernardes; Arsenio M. Fialho; Aguiar-Ricardo, Ana; Rita F Pires; Vasco D.B. Bonifácio. 2023. "Polímeros de Núcleo-Camada Catiónicos". Portugal.
    Granted/Issued
  2. Pinto, SN; Mil-Homens, Dalila; Nuno Bernardes; Arsenio M. Fialho; Aguiar-Ricardo, Ana; Rita F Pires; Vasco D.B. Bonifácio. 2021. "Cationic Core-Shell Polymers".
    Pending

Other

Other output
  1. Half- Sandwich cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype. 2020. Milheiro SA; Gonçalves J; Lopes R; Madureira M; Lobo L; Lopes A; Nogueira F; et al. http://europepmc.org/abstract/PPR/PPR153029.
    10.26434/chemrxiv.12155178.v1
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024 Core-shell polycationic polyurea pharmadendrimers kill clinically relevant bacteria and fungi without showing relevant toxicity towards mammalian cells ACS Spring 2024 (hybrid event)
(United States)
2023/12 Cytoprotective Guardians: Quantifying the cytoprotective efficiency of extracellular vesicles (EVs) against Staphylococcus aureus Alpha Hemolysin (Hla) Microbiotec´23
(Covilhã, Portugal)
2023/09 Engineered polyurea (PURE) dendrimers kill multi-drug resistant bacteria and candida strains without affecting mammalian cells International Meeting Molecules 4Life
(Portugal)
2023 Exploring the scavenging potential of extracellular vesicles (EVs) against Staphylococcus aureus alpha hemolysin (Hla) 2nd Meeting of the Portuguese Network on Extracellular Vesicles 2023
(Portugal)
2022/04 Engineered polyurea (PURE) dendrimers are potent antimicrobial agents 32nd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID)
(Lisbon, Portugal)
2022 Dendrimer nanotherapeutics: A novel anticancer task force Nanomaterials Applied to Life Sciences - NALS 2022
(Santander, Spain)
2022 PURE dendrimers against cancer cells: when mitochondria are the key player InnovDelivery'22 (Web conference)
2022 Engineered polyurea (PURE) dendrimers are a potential alternative to conventional antibiotics Asia-Pacific biofilms (Hybrid conference)
(Guangzhou, China)
2021 Virulence quantification of KPC- and OXA-48-producing Klebsiella pneumoniae isolates in a Galleria mellonella model: Towards a novel therapeutic approach using linear cationic polymers Galleria Mellonella Workshop, webinar congress
2019/02 Insights into the mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms. Gordon Research Conference on Antimicrobial Peptides
(Lucca (Barga), Italy)
2019 Optimization of confocal microscopy imaging techniques to study the diffusion-controlled action of a cationic antimicrobial peptide along Staphylococcus biofilms 29th ECCMID
(Amsterdam, Netherlands)
2019 Study of the interaction between vaginal lactobacilli, Candida albicans and Candida glabrata from physiological aspects to OMICs analyses 30th Fungal Genetics Conference
(San Francisco, United States)
2019 Insights into the mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms Gordon Conference on Antimicrobial Peptides
(Italy)
2018 Unravelling the activity and mechanism of action of pepR, a viral-derived membrane-active peptide, against Staphylococcus aureus biofilms 6th International Iberian Biophysics Congress and X Iberoamerican Congress of Biophysics
(Castellón, Spain)
2018 Unravelling the antibiofilm activity and mechanism of action of pepR 16th Iberian Peptide Meeting
(Barcelona, Spain)
2018 Activity of the viral – derived peptide pepR against Staphylococcus aureus biofilms and insights into the mechanism of action 35 th European Peptide Symposium
(Dublin, Ireland)
2017 Phasors, spectral phasors and complementary approaches 10th International Weber Symposium
(Brazil)
2017 Nanoscale Compartmentalization of PI(4,5)P2 in Living Cells and Model Membranes. A Fluorescence Spectroscopy and FRET Imaging study SPQ
(Lisbon, Portugal)
2017 Unraveling the biophysical properties of sphingolipids: from model to cell membranes International Ceramide Conference
(Izmir, Turkey)
2017 Optimization of fluorimetric and confocal microscopy techniques to unravel vancomycin activity against Staphylococcus aureus biofilms 27th ECCMID
(Vienna, Austria)
2017 Expression of the ABC transporter PDR18 is essential to counteract the negative impact of acetic acid stress on yeast plasma membrane 7 th Congress of Microbiology and Biotechnology
(Porto, Portugal)
2016 Ceramide-gel domains in living cells: understanding the role of membrane biophysical properties in cell (patho)physiology
(Porto, Portugal)
2015 Activation of TNF receptor leads to ceramide-gel domain formation in endocytic vesicles WE- Heraeus Seminar: Advanced Microscopy of Membrane Biophysics
(Bad Honnef, Germany)
2015 Ceramide-induced biophysical alterations in membranes of live cells International Ceramide Conference
(Izmir, Turkey)
2015 Unveiling the role of the trimeric autotransporter adhesin BCAM0224 in Burkholderia cenocepacia pathogenesis 6 th Congress of Microbiology and Biotechnology
(Évora, Portugal)
2014 Tackling sphingolipids’ biophysical properties to decipher their biological roles ymposium Sphingolipids in Health and Disease
(Porto, Portugal)
2014 Lipid-lipid and lipid-drug interplay in biological membranes: from membrane lipid organization to membrane physiology Invited Seminar at Université Catholique de Louvain & Louvain Drug Research Institute
(Brussels, Belgium)
2014 Imaging Ceramide platforms in model and cell membranes EMBO Workshop on “Lipid Imaging”
(Napoles, Italy)
2014 Ceramide-platforms@the endo/lysosomal pathway: a novel mechanism by which ceramide activates intracellular targets? Gordon Research Conference on Glycolipid and Sphingolipid Biology
(Ventura, United States)
2014 Ceramide-platforms@the endolysosomal pathway: a novel mechanism by which ceramide activates intracellular targets? International Conference on the Bioscience of Lipids
(Aberdeen, United Kingdom)
2014 Characterization of ceramide-induced changes on the biophysical properties of cellular membranes International Workshop on Molecular Medicine of Sphingolipids
(Kloster Banz)
2013 Ceramide and Glucosylceramide impact on membrane biophysical properties: from model to cell membranes XLII Annual Meeting Argentinian Biophysical Society
(Cordoba, Argentina)
2013 Ceramide activates endocytosis and forms ordered intracellular lipid domains in response to TNF-alpha The 9th EBSA European Biophysics Congress
(Lisbon, Portugal)
2012 Fluorescence and microscopy in membrane biophysics: Rafts, Ceramides, Amyloids and Lipid-Protein interactions XV International Symposium on Luminescence Spectrometry, , ISLS 2012
(Barcelona, Spain)
2012 Membranes domains, lipid phase diagrams, rafts and ceramides: Advanced fluorescence methodologies in membrane biophysics Strasbourg Workshop on Membrane BioPhysics
(Strasbourg, France)
2012 Ceramide: from lipid structure to membrane domains Gordon Research Conferences (Glycolipids and Sphingolipid Biology)
(Barga, Italy)
2010 Ceramides, rafts and their interplay: Biophysical perspectives International Courses on Toxicology
(Coimbra, Portugal)
2010 Rafts and ceramides: biophysical perspective of biologically relevant membrane domains 51st International Conference of the Bioscience of Lipids (ICBL)
(Bilbao, Spain)
2010 Ceramide Gel Domain Formation in a Phospholipid Bilayer: The Impact of Ceramide Acyl Chain International Student Workshop on Lipid Domains
(Israel)
2010 Fluorescence Microscopy Study of Zwitterionic Giant Unilamellar Liposomes Confined in sol-gel glasses IV Spanish Portuguese Biophysical Congress
(Zaragosa, Spain)
2010 In the Quest for New Dyes for 3D-Bioinaging 10th National Meeting on Photochemistry
(Porto, Portugal)
2009 Rafts, ceramides, and fluid lipids:Phase diagrams determination from photophysical methodologies Fluorescence 2009
(Mumbai, India)
2008 Biophysics of rafts and their interplay with ceramides 49th International Conference on Bioscience of Lipids
(Maastricht, Netherlands)
2008 Ceramide, sphingomyelin and unsaturated lipids in the absence of cholesterol: Phase diagrams, gel phases and their biological relevance 1st Portuguese-Spanish-British Biophysics Congress
(Lisbon, Portugal)
2008 A closer look into ceramide domains: exploring the influence of ceramide on domains morphology FEBS Combined Practical and Lecture Courses - Microspectroscopy: monitoring molecular interactions in living cells.
(Wagening, Netherlands)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/01 - Current Exosome-mimetic nanoplatforms for bacterial toxin neutralization
Co-supervisor of DIOGO FILIPE TRAITOLAS GONÇALVES
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/01 - Current Light-propelled Janus nanovehicles for drug delivery
Co-supervisor of Pedro Alexandre De Sousa Rosa
 Material Engineering (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/01 - Current Dissecting the potential of Pseudomonas as a new malaria transmission blocking tool
Co-supervisor of MARIA DUARTE DE CARVALHO
 Tropical Diseases and Global Health (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024/01 - Current Combination of Cationic Polyurea dendrimers with Quorum Sensing Inhibitor to eradicate bacterial biofilms
Supervisor
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/01 - Current Screening of the anticancer potenial of limonene oligosulfides
Co-supervisor of Carolina Vanda Baranowska Baltasar Rodrigues
2024/01 - Current Nanoscale probing of membrane order in the vicinity of membrane proteins by imaging methodologies
Co-supervisor of Inês Alexandra Pires de Carvalho
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023 - Current Analysis of extracellular vesicle heterogeneity: Biophysical differences between subpopulations and their therapeutical potential
Co-supervisor
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - Current Dendrimer nanotherapeutics: A novel anticancer task force
Co-supervisor of Adriana Cruz
2021 - Current Engineered Exosomes for Amyloid-beta Scavenging
Co-supervisor of Ricardo Miguel Medalha da Silva
2022 - 2023/12 Characterization of the biofilm formation potential of bacteria associated with the midgut of the Anopheles mosquito, vector of malaria transmission
Co-supervisor
2023 - 2023/07 Antibacterial and anti-biofilm effect of metallic nanoparticles conjugated with natural compounds
Supervisor of Matilde de Assis Baptista Balbino Gradil
“Projeto Integrador de 1º ciclo (PIC)” for biological engineering degree (Other)
2023 - 2023/07 Optimization of RNA extraction methods from biofilm samples of Staphylococcus aureus
Supervisor
 “Projeto Integrador de 1º ciclo (PIC)” for biological engineering degree (Other)
2022/01 - 2022/12 Development of exosomes with bacterial antivirulence potential
Co-supervisor
2021 - 2022/12 Impact of membrane tension on plasma membrane organization and structure
Co-supervisor
2022 - 2022/07 Identification of the ideal lipid environment for alpha-hemolysin binding
Co-supervisor
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09 - 2021/01 Empowering Antibiotic Polymer Design through Coarse­-Grained Molecular Dynamics
Co-supervisor
2020/09 - 2021 Modulation of cellular responses to thermal and membrane tension stress by the multi-functional phospholipid PI(4,5)P2
Co-supervisor
2019/09/02 - 2020/12 Novel strategies for anti-cancer therapeutics using lipid droplets labelling and cationic polyurea dendrimers
Supervisor of Patricia Antunes
 Biotecnologia (Master)
2020/02 - 2020/06 Dual luminescence-based nanosensors for intracellular oxygen and temperature mapping
Co-supervisor of André Morgado
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/01 - 2020/06 Using Advanced Fluorescence Microscopy to Monitor Lipid Clustering During Virus-Like Particle Formation
Co-supervisor of Diogo Reis
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/08/01 - 2020 Insights into the killing mechanism of biomimetic antimicrobial polymers using molecular dynamic simulations
Co-supervisor of Gabriel Nascimento Serafim
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/09/03 - 2019/11/25 Polyurea dendrimers as potential multi-stage antimalarial agents
Supervisor of Guilherme Eduardo Leal Cardoso
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/08/01 - 2019/11/25 Dendrimer based anticancer agents
Supervisor of José Manuel Almeida Barbosa
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/07 - 2019/07 Biomimetic antimicrobial polymers
Supervisor of Pedro Rodrigues
2018/07 - 2018/07 Development of new polymeric antimicrobial agents
Supervisor of Tânia Albuquerque
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/09 - 2015/12 Reverse Lipofection for Spatially Defined Transfection with DNA/Cationic Lipoplexes
Co-supervisor
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/11 - 2023/11 Sandra Pinto was member of the organizing commission of the third iBB Workshop (2023/11 - 2023/11)
Meeting (Member of the Organising Committee)
2023 - 2023/05 Sandra Pinto was a member of the organizing committee of the 2023 Open day of Microscopy at Instituto Superior Técnico (2023 - 2023/05)
Workshop (Co-organisor)
 Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 - 2019 Sandra Pinto was a member of the organizing committee of the 2019 Open day of Microscopy at Instituto Superior Técnico (2019 - 2019)
Workshop (Co-organisor)
 Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 - 2019 Sandra Pinto was member of the organizing commission of the first iBB Workshop (2019 - 2019)
Seminar (Member of the Organising Committee)
 Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 - 2019 Sandra Pinto was member of the local organizing committee of the International Microorganism Day (2019 - 2019)
Other (Member of the Organising Committee)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023 Identificação in silico e validação experimental de novos fármacos inibidores de efluxo ou biofilmes em Staphylococcus aureus
(Thesis) Main arguer
 Carolina Jorge Antunes (Master)
2022 Finding 3D Nanostructures and a Novel Factor in Human DNA Replication Initiation
(Thesis) Main arguer
 Joana Dos Santos Nobre da Costa (Master)
2022 Peptide-functionalized Polymeric Nanoparticles for Cancer Therapy Applications
(Thesis) Main arguer
 Sílvia Catarina da Silva Lobo (Master)
2020 Novel strategies for anti-cancer therapeutics using lipid droplets labelling and cationic polyurea dendrimers
Supervisor
 Patrícia Antunes (Master)

Association member

Society Organization name Role
2023 - Current Portuguese Society of Chemistry (SPQ)
2018 - Current European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
2017 - Current Portuguese Society of Microbiology (SPM)

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2023 - Current Member of the PhD Thesis Committee of Manuel Carvalho in Applied Environmental Microbiology
2021 - Current Member of the PhD Thesis Committee of Cindy Alexandra Lopes Mendes in Health Sciences
Member

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2019 Interview about wining prize Bolsa de Investigação em Mieloma Múltiplo 2019 Oncologia e Hematologia
2019 Sandra Pinto and the other team members were interviewed by "My Hematology" in the occasion of the award "3rd edition of the Multiple Myeloma Research Fellowship". In the article she explains how the research on osteogenic differentiation may lead to a novel therapy to treat multiple myeloma . My Hematology
2018/02/21 Research paper (DOI: 10.1128/AEM.02850-17) highlighted in portugueses media . Público
2018/02/09 Research Paper highlighted ((DOI: 10.1128/AEM.02850-17) in portugueses media Diário de Notícias
Distinctions

Award

2019 3rd edition of the Multiple Myeloma Research Fellowship

Other distinction

2019 Journal Topic Board - Molecules
2017 Figure selected for back cover of Physical Chemistry Chemical Physics - Cryptolepine and quindoline: understanding their photophysics
2015 Figure selected for cover of Journal of Lipid Research - Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties
2014 J Lipid Res paper (doi: 10.1194/jlr.M042002) selected as a research highlight for the January 2014 issue
2010 Grant awarded from the conference International Student Workshop on Lipid Domains, Israel
2009 Grant awarded from the conference 5th International Charleston Ceramide Conference
2008 FEBS Youth Travel Grant awarded
2008 Figure selected for cover of Biophys J - Membrane domain formation, interdigitation and morphological alterations induced by the very long chain asymmetric C24:1 ceramide