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Identification

Personal identification

Full name
João Rafael Campos do Vale

Citation names

  • João R. Vale

Author identifiers

Ciência ID
DF1D-6E5E-9EE7
ORCID iD
0000-0003-0411-9618

Email addresses

  • jvale@edu.ulisboa.pt (Professional)

Telephones

Mobile phone
  • (+351) 969701401 (Personal)

Addresses

  • Rua Frei Fernão Rodrigues Monteiro, L30, 2DRT, 2655-354, Ericeira, Mafra, Portugal (Personal)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2017/03 - 2023/03
Concluded
 Pharmaceutical and Therapeutic Chemistry (Cotutelle) (Doutoramento)
Major in Organic Chemistry
Universidade de Lisboa Faculdade de Farmácia, Portugal

Tampereen yliopisto, Finland
"Photochemical Reactions of Acylsilanes towards the construction of carbon-carbon bonds" (THESIS/DISSERTATION)
 Approved with Distinction and Honors
2013/09 - 2015/11
Concluded
 Química Bioorgânica (Mestrado integrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/09 - 2013/07
Concluded
 Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
Affiliation

Science

Category
Host institution 		Employer
2022/07 - Current Science and Technology Management Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/11 - 2016/07 Researcher (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2021/08 - 2022/05 Valorização sintética da unidade de furano derivada de fontes bio-renováveis
PTDC/QUI-QOR/32008/2017
PhD Student Fellow
Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento
Concluded
2017/03 - 2021/05 Diazo-free C-H insertion of acylsilanes towards new cyclic silanes
SFRH/BD/120119/2016
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2015/03 - 2015/07 (R, S)- Resolução-separação de álcoois secundários por tecnologia enzimática de miniemulsão
PTDC/QUI-QUI/119210/2010
 Fundação para a Ciência e a Tecnologia, I.P. (Lisbon, Portugal)

Contract

Designation Funders
2025 - Current Development of a novel class of modular and stable organic photocatalysts
2023.09224.CEECIND
 Fundação para a Ciência e a Tecnologia
Outputs

Publications

Book chapter
  1. Carlos A. M. Afonso; Nuno R. Candeias; Dulce Pereira Simão; Alexandre F. Trindade; Jaime A. S. Coelho; Bin Tan; Robert Franzén. "Grignard Like Reaction in Water". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom. Portugal, 2016.
    Published
Journal article
  1. João R. Vale; Milene A. G. Fortunato; Késsia H. S. Andrade; Ângelo M. R. Rocha; Carlos Alberto Mateus Afonso; Filipa Siopa. "From Pyridine to (-)-Agelastatin A". Advanced Synthesis Catalysis (2023): http://dx.doi.org/10.1002/adsc.202300560.
    10.1002/adsc.202300560
  2. João R. Vale; Rafael F. Gomes; Carlos Alberto Mateus Afonso; Nuno R. Candeias. "Functionalized Cyclopentenes via the Formal [4+1] Cycloaddition of Photogenerated Siloxycarbenes from Acyl Silanes". The Journal of Organic Chemistry 87 14 (2022): 8910-8920. http://dx.doi.org/10.1021/acs.joc.2c00591.
    10.1021/acs.joc.2c00591
  3. Juliana G. Pereira; João M. J. M. Ravasco; João R. Vale; Fausto Queda; Rafael Gomes. "A direct Diels–Alder reaction of chitin derived 3-acetamido-5-acetylfuran". Green Chemistry 24 18 (2022): 7131-7136. http://dx.doi.org/10.1039/d2gc00253a.
    10.1039/d2gc00253a
  4. Anisha Viswanathan; Aliyu Musa; Akshaya Murugesan; João R. Vale; Carlos A. M. Afonso; Saravanan Konda Mani; Olli Yli-Harja; Nuno R. Candeias; Meenakshisundaram Kandhavelu. "Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)". Cells (2019): https://doi.org/10.3390/cells8121624.
    10.3390/cells8121624
  5. Benedicta Assoah; Vesa Riihonen; João R. Vale; Arto Valkonen; Nuno R. Candeias. "Synthesis of 6,12-Disubstituted Methanodibenzo[b,f][1,5]dioxocins: Pyrrolidine Catalyzed Self-Condensation of 2'-Hydroxyacetophenones". Molecules 24 13 (2019): 2405-2405. http://dx.doi.org/10.3390/molecules24132405.
    10.3390/molecules24132405
  6. Jagadish Kashinath Salunke; Xing Guo; Zhenhua Lin; João R. Vale; Nuno R. Candeias; Mathias Nyman; Staffan Dahlström; et al. "Phenothiazine-Based Hole-Transporting Materials toward Eco-friendly Perovskite Solar Cells". ACS Applied Energy Materials 2 5 (2019): 3021-3027. http://dx.doi.org/10.1021/acsaem.9b00408.
    10.1021/acsaem.9b00408
  7. João R. Vale; Arto Valkonen; Carlos Alberto Mateus Afonso; Nuno R. Candeias. "Synthesis of silacyclopent-2-en-4-ols via intramolecular [2 + 2] photocycloaddition of benzoyl(allyl)silanes". Organic Chemistry Frontiers 6 22 (2019): 3793-3798. http://dx.doi.org/10.1039/c9qo01028a.
    10.1039/c9qo01028a
  8. Tatu Rimpiläinen; Joana Andrade; Alexandra Nunes; Epole Ntungwe; Ana S. Fernandes; João R. Vale; João Rodrigues; et al. "Aminobenzylated 4-Nitrophenols as Antibacterial Agents Obtained from 5-Nitrosalicylaldehyde through a Petasis Borono–Mannich Reaction". ACS Omega 3 11 (2018): 16191-16202. http://dx.doi.org/10.1021/acsomega.8b02381.
    10.1021/acsomega.8b02381
  9. Benedicta Assoah; João R. Vale; Elina Kalenius; Luis Filipe Veiros; Nuno R. Candeias. "Lewis Base Catalyzed Intramolecular Reduction of Salicylaldehydes by Pinacol-Derived Chlorohydrosilane". European Journal of Organic Chemistry 2018 23 (2018): 2910-2917. http://dx.doi.org/10.1002/ejoc.201800544.
    10.1002/ejoc.201800544
  10. João R. Vale; Tatu Rimpiläinen; Elina Sievänen; Kari Rissanen; Carlos Alberto Mateus Afonso; Nuno R. Candeias. "Pot-Economy Autooxidative Condensation of 2-Aryl-2-lithio-1,3-dithianes". The Journal of Organic Chemistry 83 4 (2018): 1948-1958. http://dx.doi.org/10.1021/acs.joc.7b02896.
    10.1021/acs.joc.7b02896
  11. João R. Vale; Filipa Siopa; Paula S. Branco; Carlos A. M. Afonso. "Ring Opening of 6-Azabicyclo­[3.1.0]hex-3-en-2-ols in Water under Mild Conditions". European Journal of Organic Chemistry 2016 11 (2016): 2048-2053. http://dx.doi.org/10.1002/ejoc.201501468.
    10.1002/ejoc.201501468
Preprint
  1. Rafael Gomes; Rafael Vale; Carlos Afonso. "Orthogonally protected diaminocyclopentenones as versatile synthons: Total synthesis of (±)-Agelastatin A (Submitted to Organic Letters)". 2022. http://dx.doi.org/10.26434/chemrxiv-2022-td42k.
    10.26434/chemrxiv-2022-td42k
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/01/22 Total synthesis of marine natural product (-)-agelastatin A 15th National Organic Chemistry Meeting
Sociedade Portuguesa da Química (Portugal)
2023/02 Photochemistry of acylsilanes Biomass4Synthons Winter School – Photosynthesis and Photocatalysis
Biomass4Synthons (Sofia, Bulgaria)
2022/07 Total synthesis of (-)-agelastatin A via photochemical transformation of pyridinium salt 13th i-Med Postgraduate Students meeting
iMed.Ulisboa (Lisboa, Portugal)
2022/03 Cycloaddition reaction of photogenerated siloxy carbene 14th SPQ National Organic Chemistry Meeting
Sociedade Portuguesa da Química (Caparica, Portugal)
2021/09 Formal (4+1) cycloaddition of photogenerated siloxy carbene at International symposium on synthesis and catalysis
Sociedade Portuguesa da Química (Évora, Portugal)
2021/06 Formal (4+1) cycloaddition of photogenerated siloxy carbene 2nd Meeting of the Group of Portuguese Chemists Abroad of the SPQ
Sociedade Portuguesa da Química (Portugal)
2017/01 Synthesis of new Acylsilanes Winter School 2017, Conference Cruise Helsinki-Stockholm
Suomen Synteettisen Kemian Seura (Finland)