Liliana Cristina Pereira Montezinho (DF1F-AC3C-D459)

Curriculum Vitae

Liliana Cristina Pereira Montezinho

Liliana Cristina Pereira Montezinho is an Assistant Professor at Vasco da Gama University School, where she teaches in the Integrated Master's Degree in Veterinary Medicine and the Degree in Bioveterinary Sciences. She has a good publication record with 25 articles published in peer-reviewed journals and two book chapters. Additionally, she holds one registered patent. From 2006 to 2014, Liliana worked as a Research Scientist at Lundbeck A/S, a pharmaceutical company in Denmark. During this period, she actively contributed to and led research projects focused on developing new drugs for the treatment of neurological diseases. Between 2014 and 2017, Liliana served as a consultant for "Eurotrials A/S Scientific Consultants," engaging in various medical writing activities. Since 2015, she has been an Assistant Professor at Vasco da Gama University School in Coimbra, responsible for teaching different Biochemistry Curricular Units in the Integrated cycle of studies leading to a Master's degree in Veterinary Medicine and a degree in Bioveterinary Sciences. As a European Commission expert since 2016 (CT-EX2016D288365), Liliana has evaluated a total of 28 projects under The Marie Sklodowska-Curie Actions. At Vasco da Gama University School, she actively participates in multiple committees, including holding key positions such as Vice-President of the Scientific Council, Coordinator of the Skills Accreditation Committee, and Member of the EUVG Ethics Committee. Liliana's professional career spans various areas of fundamental, applied, and clinical research. She has become a member of the Vasco da Gama Research Center (CIVG) and collaborates with the CNC research group, specifically the Mitochondrial Toxicology and Experimental Therapeutics Laboratory at the Center for Neuroscience and Cell Biology. In this role, she contributes as a member to funded research projects in the field of medical sciences.

Read full resume ↓

Identification

Personal identification

Full name: Liliana Cristina Pereira Montezinho

Citation names

Montezinho, LP

Author identifiers

Ciência ID: DF1F-AC3C-D459
ORCID iD: 0000-0002-6877-4286

Education

	Degree	Classification
2001 - 2006 Concluded	Bioquímica (Doutoramento) Major in Biofísica Celular Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Efeitos do lítio nos processos de transdução de sinal acoplados à adenilato ciclase: importância para o tratamento da doença bipolar" (THESIS/DISSERTATION)	Magna Cum Laude
2006 Concluded	Bioquímica (Doutoramento) Major in Especialidade: Biofísica Celular Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Efeitos do Lítio Nos Processos de Transdução de Sinal Acoplados À Adenilato Ciclase. Importância para o Tratamento da Doença Bipolar" (THESIS/DISSERTATION)
1995 - 2000 Concluded	Bioquímica (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Estudos de transporte, ligação e competição do Lítio em células cromafins bovinas" (THESIS/DISSERTATION)	16

Affiliation

Science

	Category Host institution	Employer
2008 - 2014	Principal Investigator (Research)	H Lundbeck A/S, Denmark
	H Lundbeck A/S, Denmark
2006 - 2008	Postdoc (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	H Lundbeck A/S, Denmark

Teaching in Higher Education

	Category Host institution	Employer
2025/02/01 - Current	Associate Professor (University Teacher)	Associação Cognitária S Jorge de Milréu, Portugal
	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2023/09/01 - Current	Invited Assistant Professor (University Teacher)	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/02/01 - 2025/01/31	Assistant Professor (University Teacher)	Escola Universitária Vasco da Gama, Portugal

Positions / Appointments

	Category Host institution	Employer
2019 - 2021	President of the Scientific Council / Technical-Scientific Council or Equivalent	Escola Universitária Vasco da Gama, Portugal

Others

	Category Host institution	Employer
2024/06/01 - Current	President of the Ethics Committee	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal

2021/01/28 - Current	Vice-President of the Scientific Council / Technical-Scientific Council or Equivalent	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal

2014 - 2017	External Consultant	CTI Clinical Trial and Consulting Services Lisbon, Portugal
	CTI Clinical Trial and Consulting Services Lisbon, Portugal

Projects

Grant

	Designation	Funders
2022/01/01 - 2023/12/31	Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis EXPL/BTM-TEC/1407/2021 Researcher Universidade de Coimbra, Portugal Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/07/26 - 2021/07/25	Restoring the Functionality to the Injured Spinal Cord Through the Combinatory Action of Pharmaco-Therapies and Tissue Engineering Strategies PTDC/CAL-EST/29206/2017 Researcher Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/05/01 - 2021/04/30	Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype PTDC/MED-FAR/29391/2017 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/10 - 2015/09	immunotherapy with alpha-synuclein specific antibody Synuclein Therapeutic Acceleration Program (SynT AP 2013) Synuclein Therapeutic Acceleration Program (SynT AP 2013) Researcher H Lundbeck A/S, Denmark	Michael J Fox Foundation for Parkinson's Research Concluded
2006 - 2008	Study of the pro-cognitive properties of antidepressants in animal models of depression SFRH/BPD/18389/2004 Post-doc Fellow H Lundbeck A/S, Denmark	Fundação para a Ciência e a Tecnologia Concluded
2001 - 2005	Effects of lithium on signal transduction processes coupled to adenylate cyclase: importance for the treatment of bipolar disorder SFRH/BD/3286/2000 PhD Student Fellow Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2000/09/01 - 2001/06/30	Cellular and molecular targets of the therapeutic action of Li+ in bipolar disease POCTI/36160/BCI/2000 Researcher Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Other

	Designation	Funders
2000/07/01 - 2001/12/31	Cellular and Molecular Targets of the Therapeutic Action of Li+ in Bipolar Disorder POCTI/1999/BCI/36160 Other

Outputs

Publications

Book chapter	Crans, Debbie C.; Barkley, Noah E.; Montezinho, Liliana; Castro, M. Margarida. "CHAPTER 7. Vanadium Compounds as Enzyme Inhibitors with a Focus on Anticancer Effects". In Metal-based Anticancer Agents, 169-195. Royal Society of Chemistry, 2019. 10.1039/9781788016452-00169 P., Carla; P., Liliana; C.A. Castro, M. Margarida. "Li+ in Bipolar Disorder – Possible Mechanisms of Its Pharmacological Mode of Action". In Bipolar Disorder - A Portrait of a Complex Mood Disorder. InTech, 2012. 10.5772/34560
Conference abstract	Montezinho, LP; C. Teixeira; C. Marques; M.C. Baptista; Jorge Pimenta; Teixeira, José; Cagide, Fernando; et al. "Beneficial effect of mitochondriotropic antioxidants on oocyte maturation and embryo production". Paper presented in European Society for Clinical Investigation (ESCI), ESCI Virtual Meeting - COVID Edition, 2020. Published • 10.1111/eci.13109 Montezinho, LP. "Warburg effect in queens with spontaneous mammary tumors". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019. Published Montezinho, LP. "Understanding the cell growth profile of lymphoblasts to study as a model to discover the amyotrophic lateral sclerosis disease mechanisms". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
Conference paper	Carlos Vitorino; Ana Catarina Figueira; Asta Tvarijonaviciute; Anabela Almeida; Montezinho, LP; Ana Cristina Silvestre Ferreira; Melissa Almeida; et al. "Warburg effect in feline lymphoma". Paper presented in Annual Congress of the European Society of Veterinary Oncology (ESVONC), 2021. Accepted
Conference poster	Carina Sacoor; Márcia Aleixo; Ana C. Figueira; Hugo Vilhena; Paulo Oliveira; José Teixeira; Montezinho, Liliana. Corresponding author: Montezinho, Liliana. "Assessment of plasma Zonulin levels in cats with inflammatory conditions: a pilot study". Paper presented in 48th World Small Animal Veterinary Association Congress and 28th FECAVA Eurocongress, 2023. Montezinho, LP; J. Santos; C. Marques; M.C. Baptista; J. Pimenta; J. Teixeira; F. Cagide; et al. "Impacts of a novel mitochondrial-directed antioxidant on bovine sperm function and in vitro embryo development". Paper presented in 55th Annual Scientific Meeting - ESCI Virtual 2021, 2021. Montezinho, LP. "Effect of a new mitochondriotropic antioxidant on oocyte maturation and embryo production". Paper presented in The European Federation of Animal Science (EAAP)- Online virtual meeting, 2020. Montezinho, LP. "Quantification of zonulin plasma levels in felines with inflammatory disease: a pilot study". Paper presented in XVI Congresso Internacional Veterinário Montenegro, 2020. Montezinho, LP. "Lu AA21004, a novel multimodal antidepressant". Paper presented in American Society for Experimental NeuroTherapeutics, 2012. Montezinho, LP; Bundgaard C; Montezinho LP; Anderson N; Thomsen C; Mørk A. "Selegiline induces a wake promoting effect in rats which is related to formation of its active metabolites". Paper presented in Society for Neuroscience Meeting, Washington, 2011. 10.1016/j.pbb.2016.10.003 Montezinho, LP. "Lu AA21004, a novel antidepressant with multimodal activity modulates brain neurotransmitter levels and hippocampal theta oscillations, and exerts procognitive effects in preclinical models". Paper presented in 24th ECNP Congress, 2011. Montezinho, LP. "Acute treatment with the selective serotonin reuptake inhibitor escitalopram potentiates memory consolidation in rats". Paper presented in Society for Neuroscience Meeting, Washington, 2008. Montezinho, LP. "1-aminoindan, a main metabolite of rasagiline, enhances dopamine release and provides symptomatic benefit in an animal model of Parkinson’s disease". Paper presented in XVIIth World Congress on Parkinson’s Disease and Related Disorders, 2007. Montezinho, LP. "Escitalopram modulates fear conditioning in rats". Paper presented in 20th ECNP Congress, 2007. Montezinho, LP. "Effects of mood stabilizing drugs on dopamine D2-like and beta-adrenergic receptors present in rat prefrontal cortex". Paper presented in Satellite Symposium on Lithium, 2005. Montezinho, LP; Montezinho, L.P.; Duarte, C.B.; Foneeca, C.P.; Geraldes, C.F.G.; Castro, A.. "Intracellular cAMP levels regulate the accumulation of lithium in neuronal cells". Paper presented in 17th ECNP Congress, 2004. 10.1016/s0924-977x(04)80188-3 Montezinho, LP. "Studies of lithium effects in neuronal cellular models: towards the understanding of the therapeutic action of this drug". Paper presented in 39 Congresso Ibérico de Espectroscopia, 2004. Montezinho, LP. "Li+ influx and binding, and Li+/Mg2+ competition in bovine chromaffin cells as studied by 7Li NMR and fluorescence spectroscopy". Paper presented in VII Encontro de Usuários de Ressonância Magnética Nuclear, 2001. Montezinho, LP. "Molecular mechanisms of the therapeutic action of lithium in manic-depression". Paper presented in 6th FIGIPS Meeting in Inorganic Chemistry, 2001.
Journal article	Teresa Cunha-Oliveira; Liliana Montezinho; Rui F. Simões; Marcelo Carvalho; Elisabete Ferreiro; Filomena S. G. Silva. "Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis". Cells (2024): https://doi.org/10.3390/cells13030248. 10.3390/cells13030248 Sacoor, Carina; Marugg, John D.; Lima, Nuno R.; Empadinhas, Nuno; Montezinho, Liliana. "Gut-Brain Axis Impact on Canine Anxiety Disorders: New Challenges for Behavioral Veterinary Medicine". Veterinary Medicine International 2024 (2024): 1-10. http://dx.doi.org/10.1155/2024/2856759. Published • 10.1155/2024/2856759 Santos, João Campos; Marques, Carla Cruz; Baptista, Maria Conceição; Pimenta, Jorge; Teixeira, José; Montezinho, Liliana; Cagide, Fernando; et al. "Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production". (2022): http://hdl.handle.net/10316/102837. https://doi.org/10.3390/ani12070804 Sacoor, Carina; Barros, Luís Meireles; Montezinho, Liliana. "What are the potential biomarkers that should be considered in diagnosing and managing canine chronic inflammatory enteropathies?". Open Veterinary Journal 10 4 (2021): 412-430. http://dx.doi.org/10.4314/ovj.v10i4.9. 10.4314/ovj.v10i4.9 Teresa Cunha-Oliveira; Liliana Montezinho; Catarina Mendes; Omidreza Firuzi; Luciano Saso; Paulo J. Oliveira; Filomena S. G. Silva; et al. "Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-29. https://doi.org/10.1155/2020/5021694. 10.1155/2020/5021694 Grattagliano, Ignazio; Montezinho, Liliana P.; Oliveira, Paulo J.; Frühbeck, Gema; Gómez-Ambrosi, Javier; Montecucco, Fabrizio; Carbone, Federico; et al. "Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease". Biochemical pharmacology (2019): http://hdl.handle.net/10316/95077. https://doi.org/10.1016/j.bcp.2018.11.020 Majbour NK; Vaikath NN; van Dijk KD; Ardah MT; Varghese S; Vesterager LB; Montezinho LP; et al. "Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.". (2016): http://europepmc.org/abstract/med/26782965. 10.1186/s13024-016-0072-9 Thirstrup K; Sotty F; Montezinho LC; Badolo L; Thougaard A; Kristjánsson M; Jensen T; Watson S; Nielsen SM. "Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.". (2015): http://europepmc.org/abstract/med/26731018. 10.1016/j.phrs.2015.12.028 Heegaard, Niels HH; Tanassi, Julia T; Bech, Sara; Salvesen, Lisette; Jensen, Peter Lüttge; Montezinho, Liliana CP; Winge, Kristian. "Cerebrospinal fluid a-synuclein in the differential diagnosis of parkinsonian syndromes". Future Neurology 9 5 (2014): 525-532. http://dx.doi.org/10.2217/fnl.14.51. 10.2217/fnl.14.51 Redrobe JP; Jørgensen M; Christoffersen CT; Montezinho LP; Bastlund JF; Carnerup M; Bundgaard C; Lerdrup L; Plath N. "In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia.". (2014): http://europepmc.org/abstract/med/24577516. 10.1007/s00213-014-3492-7 Sørensen G; Husum H; Brennum LT; Bundgaard C; Montezinho LC; Mørk A; Wörtwein G; Woldbye DP. "Addiction-related effects of DOV 216,303 and cocaine: A comparative study in the mouse.". (2014): http://europepmc.org/abstract/med/24314270. 10.1111/bcpt.12182 Fonseca CP; Fonseca LL; Montezinho LP; Alves PM; Santos H; Castro MM; Geraldes CF. "23Na multiple quantum filtered NMR characterisation of Na+ binding and dynamics in animal cells: a comparative study and effect of Na+/Li + competition.". (2013): http://europepmc.org/abstract/med/23563802. 10.1007/s00249-013-0899-8 Mørk A; Montezinho LP; Miller S; Trippodi-Murphy C; Plath N; Li Y; Gulinello M; Sanchez C. "Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats.". (2013): http://europepmc.org/abstract/med/23380522. 10.1016/j.pbb.2013.01.019 Montezinho, LP. "Lu AA21004, a novel multimodal antidepressant with activity exerted through serotonergic targets". Biological Psychiatry 71 8 (2012): 217S-316S. http://dx.doi.org/10.1016/j.biopsych.2012.02.014. 10.1016/j.biopsych.2012.02.014 Hovelsø N; Sotty F; Montezinho LP; Pinheiro PS; Herrik KF; Mørk A. "Therapeutic potential of metabotropic glutamate receptor modulators.". (2012): http://europepmc.org/abstract/med/22942876. 10.2174/157015912799362805 Montezinho LP; Miller S; Plath N; Jensen NH; Karlsson JJ; Witten L; Mørk A. "The effects of acute treatment with escitalopram on the different stages of contextual fear conditioning are reversed by atomoxetine.". (2010): http://europepmc.org/abstract/med/20676614. 10.1007/s00213-010-1917-5 Witten L; Sager T; Thirstrup K; Johansen JL; Larsen DB; Montezinho LP; Mørk A. "HIF prolyl hydroxylase inhibition augments dopamine release in the rat brain in vivo.". (2009): http://europepmc.org/abstract/med/19156859. 10.1002/jnr.21988 Sotty F; Montezinho LP; Steiniger-Brach B; Nielsen J. "Phosphodiesterase 10A inhibition modulates the sensitivity of the mesolimbic dopaminergic system to D-amphetamine: involvement of the D1-regulated feedback control of midbrain dopamine neurons.". (2009): http://europepmc.org/abstract/med/19236563. 10.1111/j.1471-4159.2009.06004.x Sotty F; Damgaard T; Montezinho LP; Mørk A; Olsen CK; Bundgaard C; Husum H. "Antipsychotic-like effect of retigabine [N-(2-Amino-4-(fluorobenzylamino)-phenyl)carbamic acid ester], a KCNQ potassium channel opener, via modulation of mesolimbic dopaminergic neurotransmission.". (2009): http://europepmc.org/abstract/med/19098162. 10.1124/jpet.108.146944 Montezinho, L.; Miller, S.; Plath, N.; Mørk, A.. "P.2.d.014 Escitalopram modulates fear conditioning in rats". European Neuropsychopharmacology 17 (2007): S369-S370. http://dx.doi.org/10.1016/s0924-977x(07)70543-6. 10.1016/s0924-977x(07)70543-6 Montezinho, Liliana P; Mørk, Arne; Duarte, Carlos B; Penschuck, Silke; Geraldes, Carlos FGC; Castro, M Margarida CA. "Effects of mood stabilizers on the inhibition of adenylate cyclase via dopamine D2-like receptors". Bipolar Disorders 9 3 (2007): 290-297. http://dx.doi.org/10.1111/j.1399-5618.2007.00354.x. 10.1111/j.1399-5618.2007.00354.x Montezinho, Liliana P.; Castro, M. Margarida C. A.; Duarte, Carlos B.; Penschuck, Silke; Geraldes, Carlos F. G. C.; Mørk, Arne; Montezinho LP; et al. "The interaction between dopamine D2-like and beta-adrenergic receptors in the prefrontal cortex is altered by mood-stabilizing agents". (2006): http://hdl.handle.net/10316/8094. https://doi.org/10.1111/j.1471-4159.2005.03654.x Fonseca CP; Jones JG; Carvalho RA; Jeffrey FM; Montezinho LP; Geraldes CF; Castro MM. "Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis.". (2005): http://europepmc.org/abstract/med/16095758. 10.1016/j.neuint.2005.06.005 Montezinho LP; B Duarte C; Fonseca CP; Glinka Y; Layden B; Mota de Freitas D; Geraldes CF; Castro MM. "Intracellular lithium and cyclic AMP levels are mutually regulated in neuronal cells.". (2004): http://europepmc.org/abstract/med/15287898. 10.1111/j.1471-4159.2004.02551.x Fonseca CP; Montezinho LP; Nabais C; Tomé AR; Freitas H; Geraldes CF; Castro MM. "Effects of Li+ transport and intracellular binding on Li+/Mg2+ competition in bovine chromaffin cells.". (2004): http://europepmc.org/abstract/med/15110989. 10.1016/j.bbamcr.2003.12.005 Montezinho LP; Fonseca CP; Geraldes CF; Castro MM; Montezinho, Liliana P.; Fonseca, Carla P.; Geraldes, Carlos F. G. C.; Castro, M. Margarida C. A.. "Quantification and localization of intracellular free mg in bovine chromaffin cells.". (2002): http://europepmc.org/abstract/med/18475427. 10.1155/MBD.2002.69 Fonseca CP; Montezinho LP; Baltazar G; Layden B; Freitas DM; Geraldes CF; Castro MM; et al. "Li influx and binding, and li/mg competition in bovine chromaffin cell suspensions as studied by li NMR and fluorescence spectroscopy.". (2000): http://europepmc.org/abstract/med/18475968. 10.1155/MBD.2000.357
Thesis / Dissertation	Lheureux, Agathe Anne-Sophie Eliane. "Evaluation Of Tumour Necrosis Factor a And Zonulin As Potential Biomarkers For Intestinal Permeability In Acute Enteropathies In Dogs". Master, 2024. http://hdl.handle.net/10400.26/52606. Gautier, Marine. "Physiotherapy And Physical Rehabilitation To Improve The Mobility And For Pain Management In Postoperative Dogs With Thoracolumbar Intervertebral Disk Extrusion". Master, 2024. http://hdl.handle.net/10400.26/52579. Le Sourd, Marine. "A Case Report Of Appendicitis In A Pet Rabbit Presented With Mild Symptoms Of Gastrointestinal Pathology". Master, 2024. http://hdl.handle.net/10400.26/52580. Pedro de Castro, Andreia Marisa. "Exploring Biomarkers for Intestinal Permeability in Dogs". Master, 2023. http://hdl.handle.net/10400.26/51186. Botelho, Ana Lourenço. "Quantification and categorisation of microplastics in wild and aquaculture fish and in the water of the Aegean Sea". Master, 2021. http://hdl.handle.net/10400.26/38130. Nunes, Ana Margarida Martins. "Chemical restraint in free-ranging phocid seals with Tiletamine and Zolazepam". Master, 2021. http://hdl.handle.net/10400.26/38086. Simões, Andreia Inês Amado. "Abordagem clínica à Diabetes Insipidus em cães e gatos". Master, 2021. http://hdl.handle.net/10400.26/38133. Bastos, Nádia Filipa Fernandes. "Discinesia paroxística em cães". Master, 2021. http://hdl.handle.net/10400.26/38170. Santos, João Pedro Campos dos. "Impacts of a novel mitochondrial-directed antioxidant on bovine sperm function and in vitro embryo development". Master, 2020. http://hdl.handle.net/10400.26/34026. Sacoor, Carina. "What potential biomarkers should be considered in diagnosing and managing canine chronic inflammatory enteropathies?". Master, 2019. http://hdl.handle.net/10400.26/29775. Almeida, Pedro Manuel Oliveira. "Orthopedic shoeing in equines". Master, 2018. http://hdl.handle.net/10400.26/24491. Barros, Ana Carolina Fernandes. "Central and peripheral vestibular syndrome in cats and dogs". Master, 2017. http://hdl.handle.net/10400.26/19010. Miranda, Ana Margarida Cabral Carvalho. "Leptospirosis in dogs: a retrospective study of 9 cases in coimbra". Master, 2015. http://hdl.handle.net/10400.26/16847. Montezinho, Liliana Cristina Pereira. "Efeitos do lítio nos processos de transdução de sinal acoplados à adenilato ciclase : importância para o tratamento da doença bipolar". PhD, 2006. http://hdl.handle.net/10316/1601. Montezinho, LP. "Lithium transport, binding and competition studies in bovine chromaffin cells". Degree, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2001.

Intellectual property

Patent

Montezinho, Liliana; Montezinho, LP. 2017. "Agents, Uses and Methods for the Treatment of Synucleinopathy".
Granted/Issued

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2014	Detection of different species of a-synuclein in plasma, extracellular fluid, CSF and brain in transgenic animal models for PD	Keystone conference (United States)
2012	Preclinical effects of Lu AA21004, a novel multimodal antidepressant	25th ECNP Congress (Austria)
2012	The novel antidepressant vortioxetine (Lu AA21004): implications of its multimodal mechanism of action in preclinical functional and behavioral models	Serotonin Club meeting
2012	Lu AA21004, a multimodal antidepressant, is active in a fluoxetine-insensitive rat model of depression and enhances cognitive function in rats	165th Annual Meeting of the American Psychiatric Association
2005	Li+ effects on the tricarboxylic acid cycle flux in the human neuroblastoma SHSY5Y cell line: a 13C NMR isotopomer analysis	Satellite Symposium on Lithium
2004	Spectroscopic studies of lithium effects on neuronal cellular models and on brain cell metabolism	Congresso Luso- Espanhol de Biofísica

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2023 - 2024	A case report of appendicitis in a pet rabbit presented with mild symptoms of gastrointestinal pathology. Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2023 - 2024	Physiotherapy and physical rehabilitation to improve the mobility and for pain management in postoperative dogs with throracolumbar intervertebral disk extrusion. Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2023 - 2024	Hypertension pulmonary in dogs. Hipertensão pulmonar em cães. Co-supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2023 - 2024	Evaluation of tumour necrosis factor a and zonulin as potential biomarkers for intestinal permeability in acute enterophaties in dogs. Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021 - 2022	Immunology of canine leishmaniasis. Imunologia da leihsmaniose canina. Co-supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021 - 2022	Perioperative analgesia in laparotomy in cats. Analgesia perioperatória em laparotomia no gato. Co-supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021 - 2022	Evaluation of Hematological Ratios in Feline Mammary Tumors. Avaliação de Rácios Hematológicos em Tumores Mamários Felinos. Co-supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021 - 2022	Search for vector-borne agents in cats with lymphoma and mammary tumors. Pesquisa de agentes de transmissão vetorial em gatos com linfoma e tumores mamários. Co-supervisor
2020 - 2021	Detection and quantification of microplastics in wild and cultured fish and in the water of the Aegean Sea and potential impacts on bottlenose dolphins (Tursiops truncatus). Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2020 - 2021	Clinical approach to Diabetes Insipidus in dogs and cats. Abordagem clínica à Diabetes Insipidus em cães e gatos. Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2020 - 2021	Discinesia paroxística em cães. Paroxysmal dyskinesia in dogs. Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2020 - 2021	Chemical restraint in free-ranging phocid seals with Tiletamine and Zolazepam. Supervisor	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2019/09/01 - 2020/07/31	Impacts of a novel mitochondrial-directed antioxidant on bovine sperm function and in vitro embryo development Supervisor
2018/09/03 - 2019/07/19	What potential biomarkers should be considered in diagnosing and managing canine chronic inflammatory enteropathies? Supervisor	Escola Universitária Vasco da Gama, Portugal
2019 - 2019	Evaluation of plasma zonulin as a potential biomarker of inflammatory disease in felines. Avaliação da zonulina plasmática como potencial biomarcador de patologia inflamatória em Felídeos. Supervisor	Medicina Veterinária (Other) Escola Universitária Vasco da Gama, Portugal
2017 - 2018	Orthopedic farriery in equines. Ferração ortopédica em equinos. Supervisor	Medicina Veterinária (Master) Escola Universitária Vasco da Gama, Portugal
2016 - 2017	Central and peripheral vestibular syndrome in dogs and cats. Síndrome Vestibular Central e Periférica em Cães e Gatos. Supervisor	Medicina Veterinária (Master) Escola Universitária Vasco da Gama, Portugal
2015 - 2015	Leptospirosis in dogs: a retrospective study of 9 cases in Coimbra Supervisor	Medicina Veterinária Escola Universitária Vasco da Gama, Portugal
2014 - 2015	Interplay between a-synuclein and neuroinflammation for the neurogenesis process and cognition in mice Supervisor	H Lundbeck A/S, Denmark
2009 - 2009	Lipopolysaccharide-induced cytokine production in the brain and plasma Supervisor	H Lundbeck A/S, Denmark

Event organisation

	Event name Type of event (Role)	Institution / Organization
2024/09/04 - 2024/09/04	I Symposium at Vasco da Gama University School on "Ethics and Bioethics in Veterinary Sciences" (Coimbra, Portugal) (2024/09/04 - 2024/09/04) Symposium (President of the Organising Committee)	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2024/09/23	Explorando o Potencial de Nanopartículas à Base de Óxido de Ferro na Terapia do Glioblastoma. Exploring the Potential of Iron Oxide-Based Nanoparticles in Glioblastoma Therapy (Thesis) Arguer	Joel Sérgio Jesus Barcelos (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2024/07/31	Evaluation of tumour necrosis factor a and zonulin as potential biomarkers for intestinal permeability in acute enterophaties in dogs. Supervisor	Agathe Anne-Sophie Eliane Lheureux (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/07/12	Rhodococcus equi em poldros: estratégias de prevenção, abordagens terapêuticas e gestão das resistências antibacterianas. Rhodococcus equi in Foals: Prevention Strategies, Therapeutic Approaches, and Management of Antibacterial Resistance. President of the jury	Clarisse Éliane Vincent Protière (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/07/12	Artrite séptica em equinos. Septic arthritis in equines President of the jury	Joel Fernando Mendes Pinheiro (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/07/11	Revisão bibliográfica: sarcoides em equinos. Literature review: sarcoids in equines. President of the jury	Bárbara Dias de Sousa (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/06/27	Análise técnico-económica de explorações de bovinos de leite em modo de produção biológico e convencional. Technical and economic analysis of dairy cattle farms in organic and conventional production systems President of the jury	Pauline Sophie Matz (Master)
2024/06/24	Physiotherapy and physical rehabilitation to improve the mobility and for pain management in postoperative dogs with throracolumbar intervertebral disk extrusion. 28 junho 2024 Supervisor	Marine Gautier (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/06/19	A case report of appendicitis in a pet rabbit presented with mild symptoms of gastrointestinal pathology. Supervisor	Marine Le Sourd (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/06/13	Medidas de controlo de Nemátodes gastrointestinais de ruminantes em Creuse, Hautes-Alpes, Alpes-de-Haute-Provence e Seine-Maritime, França. Control measures for gastrointestinal nematodes in ruminants in Creuse, Hautes-Alpes, Alpes-de-Haute-Provence, and Seine-Maritime, France. President of the jury	Louise Catherine Hélène Bouguet (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2024/06/11	A relação dos fatores do stress do ambiente com a cistite idiopática em gatos domésticos. The relationship between environmental stress factors and idiopathic cystitis in domestic cats. President of the jury	Anne Santos Amarante (Master)
2022/10/27	Hipoadrenocorticismo atípico canino. Atypical canine hypoadrenocorticism. President of the jury	Maria José Socorro Alves (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2022/07/26	Dorsal acetabular rim arthroplasty for the management of canine hip dysplasia: a case report. President of the jury	Florence Lelou (Master)
2022/06/23	O efeito das alterações climáticas nas doenças vectoriais em cães. The effect of climate change on vector-borne diseases in dogs. President of the jury	Marta dos Santos Gregório (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2022/04/27	Critérios utilizados na síndrome de resposta inflamatória sistémica (SIRS) e sépsis, na prática clínica de animais de companhia. Criteria used in systemic inflammatory response syndrome (SIRS) and sepsis, in the clinical practice of companion animals. President of the jury	Carolina Abreu Silva (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2022/01/27	Transferência de embrião em equinos com melhoramento da raça Lusitana. Embryo transfer in equines with improvement of the Lusitano breed. President of the jury	Ana Filipa Neves Morais Paulo (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021/09/30	Guia para preparação de um dossier de segurança alimentar de insetos para alimentação humana. Guide for preparing a food safety dossier on insects for human consumption. President of the jury	Ricardo José Soares de Castro Leal (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021/09/28	Chemical restraint in free-ranging phocid seals with Tiletamine and Zolazepam. Supervisor	Ana Margarida Martins Nunes. (Master)
2021/07/29	Abordagem clínica à Diabetes Insipidus em cães e gatos. Clinical approach to diabetes insipidus in dogs and cats. President of the jury	Andreia Inês Amado Simões (Master)
2021/07/27	Relação entre o microbioma bacteriano gastrointestinal com a doença inflamatória intestinal e o linfoma em cães e gatos. Relationship between the gastrointestinal bacterial microbiome, inflammatory bowel disease, and lymphoma in dogs and cats. President of the jury	Inês Ribeiro Rodrigues Almeida Medeiros (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021/07/27	Detection and quantification of microplastics in wild and cultured fish and in water of the Aegean Sea and potential impacts on bottlenose dolphins (Tursiops truncatus). Supervisor	Ana Lourenço Botelho (Master)
2021/07/26	Coxielose em bovinos de leite na região Centro/Norte de Portugal: estudo serológico e molecular. Coxiellosis in dairy cattle in the Central/Northern region of Portugal: serological and molecular study. President of the jury	Paula Oliveira Coelho (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021/07/21	Coxiella burnetti in small animals: serological and molecular study in female dogs. Coxiella burnetii in small animals: serological and molecular study in female dogs. President of the jury	Samuel Costa Anjos (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021/07/21	Glaucoma canino. Canine glaucoma. President of the jury	Rafael Carvalho Marques (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2020/07/23	Implementation of an On Farm Culture system in dairy cattle farms in Terceira Island - preliminary results President of the jury	Margarida Mendes Santos Cascão (Master) Escola Universitária Vasco da Gama, Portugal
2020/07/22	Proximal desmite of the suspensory billet ligament President of the jury	Pedro Alves Neto (Master) Escola Universitária Vasco da Gama, Portugal
2020/07/21	Septic peritonitis in cats and dogs: A retrospective study President of the jury	Diana Maria Gonçalves de Oliveira S. António (Master) Escola Universitária Vasco da Gama, Portugal
2020/07/15	Microsurgery teaching methods in Veterinary Medicine President of the jury	Francisco Miguel Costa Cunha Batalha (Master) Escola Universitária Vasco da Gama, Portugal
2020/06/05	Observation of Wasting Syndrome and diagnosis of Lentivirosis in Small Ruminants - What relationship? President of the jury	Diana Margarida da Silva Valente (Master) Escola Universitária Vasco da Gama, Portugal
2020/04/15	Cryptosporidiosis in Cattle - Bibliographic Review President of the jury	Pedro João Batista Cairrão (Master)
2019/10/08	Biological and Therapeutic Properties of Honey in the Treatment of Wounds (Thesis) Main arguer	Ivan Gonçalves dos Santos (Master)
2019/07/24	Feline psychogenic alopecia President of the jury	Ana Sofia da Silva Andrade (Master) Escola Universitária Vasco da Gama, Portugal
2019/07/17	Canine dilated cardiomyopathy, from etiology to therapeutics - what's new? President of the jury	Mariana Gusmão Pinheiro Magano Canha (Master) Escola Universitária Vasco da Gama, Portugal
2019/07/17	Primary corneal endotelial degeneration in dogs? President of the jury	Rita Cacho Miranda (Master) Escola Universitária Vasco da Gama, Portugal
2019/07/11	Canine mastocytoma: main therapeutic approaches President of the jury	Ana Carina Pereira da Silva (Master) Escola Universitária Vasco da Gama, Portugal
2019/07/11	The role of flow cytometry in the assessment of minimal residual disease in dogs with diffuse large cell B lymphoma. President of the jury	Marta Filipa Pimenta Rainho Monteiro (Master) Escola Universitária Vasco da Gama, Portugal
2019/07/09	Exotic human-animal cohabitation: addressing this growing interest President of the jury	Mariana Ribeiro da Fonseca (Master) Escola Universitária Vasco da Gama, Portugal
2019/06/07	Causes of refuse in dairy farms: Literature review President of the jury	Maria de Fátima dos Santos Martins (Master) Escola Universitária Vasco da Gama, Portugal
2018/07/05	Warburg effect in queens with mammary tumors President of the jury	Melissa Isabelle Martinho de Almeida (Master) Escola Universitária Vasco da Gama, Portugal
2018/06/13	Prospective and retrospective study of breast tumors in cats President of the jury	Filipa Alexandra Brízido Silva Fernandes (Master) Escola Universitária Vasco da Gama, Portugal
2018/06/07	Acute phase proteins in queens with pyometra – sérum amyloid alfa . President of the jury	Telma Adriana Ferreira Santos (Master) Escola Universitária Vasco da Gama, Portugal
2017/07/18	Feline hypertrophic cardiomyopathy: literature review President of the jury	António Manuel Graça Matos Pereira (Master) Escola Universitária Vasco da Gama, Portugal
2017/07/18	Main cardiac changes found in pre-anesthetic evaluations in dogs President of the jury	Rosa Alexandra Oliveira Henriques Roma (Master) Escola Universitária Vasco da Gama, Portugal
2016/07/13	Retrospective Study of Leptospirosis in the Baixo Vouga Region between 2011 and 2015 President of the jury	João Pedro Gonçalo da Cruz (Master) Escola Universitária Vasco da Gama, Portugal
2012/07/12	Hemiplegia laríngea em cavalos de desporto: abordagem e sucesso dos tratamentos. Laryngeal hemiplegia in sport horses: approach and treatment success. President of the jury	Fanny Léa Laurence Moraine (Master) Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal

Committee member

	Activity description Role	Institution / Organization
2024/06/25 - Current	President of the Ethics Committee President / Vice-president	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2021/02 - Current	Vice-President of the Scientific Council - EUVG President / Vice-president	Escola Universitária Vasco da Gama, Portugal
2021/05/13 - 2024/06/24	Member of the Ethics Committee Member	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2015/09/01 - 2024/02/01	Coordinator of the fundamental sciences area of the scientific areas committee of the integrated Master's in Veterinary Medicine Coordinator	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2017 - 2023	Coordinator of the first year in the integrated Master in Veterinary Medicine Coordinator	Escola Universitária Vasco da Gama, Portugal
2018/07 - 2021/01	President of the Scientific Council - EUVG President / Vice-president	Escola Universitária Vasco da Gama, Portugal

Consulting

	Activity description	Institution / Organization
2014 - 2017	Realization of different Medical writing ativities	CTI Clinical Trial and Consulting Services Lisbon, Portugal

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2023/09/01 - Current	Introduction to Biochemistry Laboratories
2023/09/01 - Current	Analytical Biochemistry Laboratories
2015/09/01 - Current	Biochemistry I (Biomolecules structure)	(Mestrado integrado)	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2015/02/01 - Current	Biochemistry II (Biomolecules metabolism)	(Mestrado integrado)	Escola Universitária Vasco da Gama Centro Investigação Vasco da Gama, Portugal
2015/02/01 - 2026/07/31	Genetics
2019/02/01 - 2024/08/31	Clinical Biochemistry	(Licenciatura)
2015/02/01 - 2019/09/30	Research and Development Methodologies Metodologias Investigação e Desenvolvimento
2015/02/01 - 2016/07/31	Cellular and Molecular Biology

Evaluation committee

	Activity description Role	Institution / Organization	Funding entity
2016 - Current	Evaluation of 28 Marie Sklodowska Curie Individual Fellowships. Expert number CT-EX2016D288365. Evaluator	European Commission, Belgium	European Commission

Mentoring / Tutoring

	Topic	Student name
2023/02/01 - 2023/02/28	Integrated Veterinary Practice (internship)	Jade Mireille Monique Dourlens-Monchy
2023/02/01 - 2023/02/28	Integrated Veterinary Practice (internship)	Juliana Maria Sousa Ramos
2023/02/01 - 2023/02/28	Integrated Veterinary Practice (internship)	Juliane Attika Bernard
2023/02/01 - 2023/02/28	Integrated Veterinary Practice (internship)	Justine Camille Claude Claverie
2023/02/01 - 2023/02/28	Integrated Veterinary Practice (internship)	Rita Carvalho Albano Barroso Alves
2022/02/01 - 2022/02/28	Integrated Veterinary Practice (internship)	Jorge Felipe Da Silva Do Carmo
2022/02/01 - 2022/02/28	Integrated Veterinary Practice (internship)	Julia Marie Janny Marechal
2022/02/01 - 2022/02/28	Integrated Veterinary Practice (internship)	Klara Marie Emma Fourié
2022/02/01 - 2022/02/28	Integrated Veterinary Practice (internship)	Klervie Le Duff
2022/02/01 - 2022/02/28	Integrated Veterinary Practice (internship)	Cláudia Marinho Lima
2021/02/01 - 2021/02/28	Integrated Veterinary Practice (internship)	Élise Michèle Francine Poret
2021/02/01 - 2021/02/28	Integrated Veterinary Practice (internship)	Emeric Stéphane Nicolas Gerbaud
2021/02/01 - 2021/02/28	Integrated Veterinary Practice (internship)	Helene Jeanne Yvonne Le Cavorzin
2021/02/01 - 2021/02/28	Integrated Veterinary Practice (internship)	Inaia Marie Bertrand
2021/02/01 - 2021/02/28	Integrated Veterinary Practice (internship)	Tiên San Lya Sellin
2020/02/28 - 2020/02/28	Integrated Veterinary Practice (internship)	Léa Villemagne
2020/02/03 - 2020/02/28	Integrated Veterinary Practice (internship)	Léa Godard
2020/02/03 - 2020/02/28	Integrated Veterinary Practice (internship)	Léa Mann
2020/02/03 - 2020/02/28	Integrated Veterinary Practice (internship)	Luann Blanquet
2020/02/03 - 2020/02/28	Integrated Veterinary Practice (internship)	Tânia Monteiro
2019/02/01 - 2019/02/28	Integrated Veterinary Practice (internship)	Rosalie Violette Marie Menard
2019/02/01 - 2019/02/28	Integrated Veterinary Practice (internship)	Diogo Manuel Francisco Manso
2019/02/01 - 2019/02/28	Integrated Veterinary Practice (internship)	Sabrina Khedidja Rabia Kidad-Falhi
2019/02/01 - 2019/02/28	Integrated Veterinary Practice (internship)	Sandra Gonçalves
2019/02/01 - 2019/02/28	Integrated Veterinary Practice (internship)	Anaelle Marquier
2018/02/01 - 2018/02/28	Integrated Veterinary Practice (internship)	Margaux Louise Bolzer
2018/02/01 - 2018/02/28	Integrated Veterinary Practice (internship)	Mathilde Nathalie Élisabeth Guillot
2018/02/01 - 2018/02/28	Integrated Veterinary Practice (internship)	Melanie dos Santos
2018/02/01 - 2018/02/28	Integrated Veterinary Practice (internship)	Olivier David Gérard San German
2017/02/01 - 2017/02/28	Integrated Veterinary Practice (internship)	João Miguel Fonseca Marques Pena Dias
2017/02/01 - 2017/02/28	Integrated Veterinary Practice (internship)	Luís Nuno Moreirão Cerca Monteiro Oliveira
2017/02/01 - 2017/02/28	Integrated Veterinary Practice (internship)	Mafalda Inês Jardim Fernandes
2017/02/01 - 2017/02/28	Integrated Veterinary Practice (internship)	Manuel Francisco Cortez Camões
2017/02/01 - 2017/02/01	Integrated Veterinary Practice (internship)	Mafalda Inês Jardim Fernandes
2016/02/01 - 2016/02/29	Integrated Veterinary Practice (internship)	Anthony Leal
2016/02/01 - 2016/02/28	Integrated Veterinary Practice (internship)	Catherine Castel
2016/02/01 - 2016/02/28	Integrated Veterinary Practice (internship)	Cindy Lucas
2016/02/01 - 2016/02/28	Integrated Veterinary Practice (internship)	Diana Valente
2016/02/01 - 2016/02/28	Integrated Veterinary Practice (internship)	Dulce Vieira