???global.info.a_carregar???
Ana Rita Garcia is a Fellow Researcher at Neurovascular Laboratory at Faculty of Pharmacy of University of Lisbon and affiliated to i.MedU.Lisboa - Research Institute for Medicines. Born in 1995, has graduated in Biochemistry (2016) and completed her master's in Molecular Biology and Genetics (2020). Ana Rita started her scientific activities in Neurovascular Laboratory (2018) in breast cancer brain metastasization, in specific focused on the interplay between triple-negative breast cancer cells and blood-brain barrier during extravasation process. This project allowed her to be the first author of 1 published paper (2019), first author of 3 posters (+ 3 as co-author) and 2 oral communication presented in 4 national and international meetings. Has awarded with 1 scholarship (for a year) sponsored by Liga Portuguesa Contra o Cancro / Pfizer. In 2021, started his PhD in Pharmacy, after being awarded a scholarship from the Foundation for Science and Technology (FCT), resulting in 1 publication as co-first author in an international journal, 1 book chapter and 6 posters (3 as first author and 3 as co-author) and 1 international prize. At this moment, Ana Rita is also team member of 2 scientific projects, including a pFizer Medical Grant.
Read full resume ↓
Identification

Personal identification

Full name
Ana Garcia
Date of birth
1995/04/25
Gender
Female

Citation names

  • Ana Rita Garcia
  • Garcia, AR

Author identifiers

Ciência ID
E014-A81A-B21A
ORCID iD
0000-0001-7285-0897

Email addresses

  • a25rg@hotmail.com (Professional)

Addresses

  • Avenida Professor Gama Pinto, 1649-003, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2021 - 2024
Ongoing
 Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2020
Concluded
 Biologia Molecular e Genética (Mestrado integrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Blood-brain barrier: role in brain metastasization of breast cancer" (THESIS/DISSERTATION)
 18/20
2013 - 2016
Concluded
 Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 15/20
Affiliation

Others

Category
Host institution 		Employer
2021 - 2024 Bolseiro de Investigação Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/01/01 - 2020/12/31 Bolseiro de Investigação Liga Portuguesa Contra o Cancro, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Contract

Designation Funders
2022/04/01 - 2024/03/31 Pipeline for discovery of CDK4/6 inhibitors for metastatic breast cancer treatment
Pipeline for discovery of CDK4/6 inhibitors for metastatic breast cancer treatment
Team Member
FARM-ID, Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento (FARM-ID) , Portugal
 Pfizer Portugal
Ongoing

Other

Designation Funders
2018 - 2022 Detect, prevent, eradicate: a multi-step strategy to abrogate brain metastasization of breast cancer - FCT – PTDC/MED-ONC/29402/2017
PTDC/MED-ONC/29402/2017
Other
FARM-ID, Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento (FARM-ID) , Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. "Breast cancer cells interaction with blood-brain barrier endothelial cells: deciphering hub players and crosstalk". In Prime Archives in Cancer Research, 1-45. 2021.
    Published
Conference abstract
  1. "MEF2C and miR-194-5p: novel players in breast cancer brain metastases". Paper presented in AIMS Meeting 2021, Research Competition, Lisboa, 2022.
  2. Ana Rita Garcia. "Unravelling the extravasation of breast cancer cells through blood-brain barrier endothelial cells". Paper presented in Porto Cancer Meeting 2021, Porto, 2021.
  3. Ana Rita Garcia. "Desvendando a interação entre as células de cancro da mama e as células endoteliais da barreira hematoencefálica ao longo do extravasamento". Paper presented in 2º Encontro Nacional de Jovens Investigadores em Oncologia (ENJIO), Lisboa, 2021.
  4. Ana Rita Garcia. "Molecular players involved in cellular interplay during breast cancer brain metastases formation". Paper presented in Porto Cancer Meeting 2021, Porto, 2021.
  5. "Spatio-temporal and molecular characterization of breast cancer cells extravasation through blood-brain barrier". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, Lisboa, 2021.
  6. "Disclosing molecular alterations in the blood-brain barrier endothelium during interaction with breast cancer cells: a step forward brain metastasis prevention". Paper presented in Encontro Ciência 2021, Lisboa, 2021.
  7. Ana Rita Garcia; Pereira-Godinho, Joana; Figueira, Inês; K.S, Kim; Botelho, Hugo M; Malhó, Rui; Brito, Maria Alexandra. "Breast cancer cells extravasation into the brain: a dynamic trafficking across blood-brain barrier endothelium". Paper presented in 5th Annual Meeting of Mind Brain College, Lisbon, 2019.
  8. Pereira-Godinho, Joana; Ana Rita Garcia; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra. "Enhanced in vitro model of the blood-brain barrier by either shear stress and hydrocortisone". Paper presented in 5th Annual Meeting of Mind Brain College, Lisbon, 2019.
  9. Ana Rita Garcia; Pereira-Godinho, Joana; Figueira, Inês; Botelho, Hugo M; Malhó, Rui; K.S, Kim; Brito, Maria Alexandra. "Interplay between breast cancer cells and blood-brain barrier endothelial cells along extravasation". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, Lisbon, 2019.
  10. Ana Rita Garcia; Pereira-Godinho, Joana; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra. "Improved in vitro model of the blood-brain barrier by hydrocortisone and shear stress". Paper presented in 53ª Reunião da Sociedade Anatómica Portuguesa (SAP) e 4ª Reunião Científica da Associação Anatómica Portuguesa (AAP), Lisbon, 2019.
Conference poster
  1. "MEF2C and miR-194-5p: novel players in breast cancer brain metastases". Paper presented in Aims Meeting, 2022.
  2. Ana Rita Garcia. "Unravelling the extravasation of breast cancer cells through blood-brain barrier endothelial cells". Paper presented in Porto Cancer Meeting 2021, 2021.
  3. Ana Rita Garcia. "High-throughput screening of new and old drugs: a modulator to prevent breast cancer brain metastasis.". Paper presented in AIMS Meeting 2021, Research Competition, 2021.
  4. Ana Rita Garcia. "Molecular players involved in cellular interplay during breast cancer brain metastases formation". Paper presented in Porto Cancer Meeting 2021, 2021.
  5. "Spatio-temporal and molecular characterization of breast cancer cells extravasation through blood-brain barrier". Paper presented in Imed Meeting, 2021.
  6. "Disclosing molecular alterations in the blood-brain barrier endothelium during interaction with breast cancer cells: a step forward brain metastasis prevention". Paper presented in Encontro Ciência 2021, 2021.
  7. Ana Rita Garcia. "Metástases cerebrais do cancro da mama: descoberta dos intervenientes celulares e moleculares". Paper presented in 2º Encontro Nacional de Jovens Investigadores em Oncologia (ENJIO), 2020.
  8. Ana Rita Garcia. "Desvendando a interação entre as células de cancro da mama e as células endoteliais da barreira hematoencefálica ao longo do extravasamento". Paper presented in 2º Encontro Nacional de Jovens Investigadores em Oncologia (ENJIO), 2020.
  9. Garcia, Ana; Pereira-Godinho, Joana; Figueira, Inês; K.S, Kim; Botelho, Hugo M; Malhó, Rui; Brito, Maria Alexandra. "Breast cancer cells extravasation into the brain: a dynamic trafficking across blood-brain barrier endothelium.". Paper presented in 5th Annual Meeting of Mind Brain College, 2019.
  10. Pereira-Godinho, Joana; Garcia, Ana; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra. "Enhanced in vitro model of the blood-brain barrier by either shear stress and hydrocortisone". Paper presented in 5th Annual Meeting of Mind Brain College, University of Lisbon, 2019.
  11. Garcia, Ana; Pereira-Godinho, Joana; Figueira, Inês; Botelho, Hugo M; Malhó, Rui; Brito, Maria Alexandra. "Interplay between breast cancer cells and blood-brain barrier endothelial cells along extravasation.". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, 2019.
  12. Garcia, Ana; Pereira-Godinho, Joana; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra. "Improved in vitro model of the blood-brain barrier by hydrocortisone and shear stress". Paper presented in 53ª Reunião da Sociedade Anatómica Portuguesa (SAP) e 4ª Reunião Científica da Associação Anatómica Portuguesa (AAP), 2019.
Journal article
  1. Godinho-Pereira, Joana; Garcia, Ana Rita; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra. "Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood–Brain Barrier Disruption". International Journal of Molecular Sciences 22 13 (2021): 7057. http://dx.doi.org/10.3390/ijms22137057.
    Published • 10.3390/ijms22137057
  2. Garcia, Ana; Pereira-Godinho, Joana; Figueira, Inês; Malhó, Rui; Brito, Maria Alexandra. "Replicating the blood-brain barrier properties in an in vitro model: effects of hydrocortisone and/or shear stress". Official Journal of the Portuguese Anatomical Society (SAP/AAP) (2019): 4-20.
    Published
Thesis / Dissertation
  1. Garcia, Ana. "Blood-brain barrier: role in brain metastasization of breast cancer". Master, Universidade de Lisboa Faculdade de Ciências, 2020.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021 Metástases encefálicas de cancro da mama: caracterização espácio-temporal da interação entre as células de cancro da mama e da barreira hematoencefálica IX Jornadas de Investigação em Biologia
(Lisboa, Portugal)
2019/11/13 Breast cancer cells extravasation into the brain: a dynamic trafficking across blood-brain barrier endothelium 5th Annual Meeting of Mind Brain College
University of Lisbon (Lisbon, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019 - Current IV Symposium of the Portuguese Glial Network (2019)
Conference (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/03/17 - 2022/03/19 Online Course - Scientific tools in biological assays: principles of cell cultures and genetics (2022/03/17 - 2022/03/19)
Conference (Member of the Organising Committee)
2021/03/18 - 2021/03/20 Online Course - Models of the Blood-brain barrier (BBB): scientific tools to target the brain (2021/03/18 - 2021/03/20)
Workshop (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019 - Current 5th Annual Meeting of Mind Brain College
Conference
 5th Annual Meeting of Mind Brain College
Universidade de Lisboa Faculdade de Medicina, Portugal
2019 - Current 11th i.Med.ULisboa Postgraduate Students Meeting
Conference
 11th i.Med.ULisboa Postgraduate Students Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - Current 53ª Reunião da Sociedade Anatómica Portuguesa (SAP) e 4ª Reunião Científica da Associação Anatómica Portuguesa (AAP)
Conference
 53ª Reunião da Sociedade Anatómica Portuguesa (SAP) e 4ª Reunião Científica da Associação Anatómica Portuguesa (AAP).
Universidade de Lisboa Faculdade de Medicina, Portugal
2018 - Current Rise INPACT – Innovative approaches in targeted therapies: Brain, Infections and Cancer
Conference
 Rise INPACT – Innovative approaches in targeted therapies: Brain, Infections and Cancer
Instituto de Medicina Molecular João Lobo Antunes, Portugal
2018 - Current 4th Meeting of the Mind Brain College
Conference
 4th Meeting of the Mind Brain College
Universidade de Lisboa Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2019 - Current Sociedade Anatómica Portuguesa (SAP) Associate
Distinctions

Award

2021 Happy Cell Competition and Giveaway, Ibidi – cells in focus
2019 LPCC/Pfizer schoolarship
Liga Portuguesa Contra o Cancro, Portugal