Manuel António Silva Santos (E312-AA71-68FC)

Curriculum Vitae

Manuel António Silva Santos

Manuel António da Silva Santos. Concluiu o Título de Agregado em Ciências Biomédicas em 2019/11/02 pela Universidade de Aveiro, Doutoramento em Bioquímica em 1992/01/27 pela University of Kent e a Licenciatura em Biologia - Ramo Científico em 1987/04/23 pela Universidade de Coimbra, Faculdade de Ciências e Tecnologia. Foi Diretor Fundador do Instituto de Biomedicina - iBiMED e do Departamento de Ciências Médicas da Universidade de Aveiro (desde 2014 até 2022), Coordena o Consórcio GenomePortugal desde a sua fundação em 2014, é Professor Catedrático da Faculdade de Medicina e Diretor Científico do Instituto Multidisciplinar do Envelhecimento (MIA-Portugal) da Universidade de Coimbra, desde 2022. Publicou 164 artigos em revistas especializadas, 12 capítulos e 4 livros. Organizou 41 eventos. Orientou 25 teses de doutoramento e coorientou 4. Orientou 17 dissertações de mestrado e coorientou 19. Orientou 14 trabalho(s) de conclusão de curso de licenciatura/bacharelato. Foi nomeado pela EMBO como Young Investigator em 2021. Participou como Investigador responsável em 31 projeto(s) de investigação e os seus interesses atuais de investigação focam na regulação e desregulação da síntese proteica e na epigenética do envelhecimento.

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Identification

Personal identification

Full name: Manuel António Silva Santos

Citation names

Santos, Manuel

Author identifiers

Ciência ID: E312-AA71-68FC
ORCID iD: 0000-0002-0437-1146
Google Scholar ID: https://scholar.google.com/citations?user=kmO2svEAAAAJ

Email addresses

msantos@ua.pt (Professional)
mansilvasantos@uc.pt (Professional)

Addresses

Multidisciplinary Institute of Ageing, MIA-Portugal, 3004-504 , Coimbra, Coimbra, Portugal (Professional)

Websites

http://www.ua.pt/ibimed (Professional)
https://www.uc.pt/mia/ (Scholar)

Knowledge fields

Medical and Health Sciences - Basic Medicine

Languages

Language	Speaking	Reading	Writing	Listening
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Beginner (A1)	Intermediate (B1)	Beginner (A1)	Beginner (A1)
Spanish; Castilian	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)

Education

	Degree	Classification
2019/01/01 - 2019/11/02 Concluded	Ciências Biomédicas (Título de Agregado) Universidade de Aveiro, Portugal	Aprovado
1992/01/27 Concluded	Biochemistry (Doutoramento) University of Kent, United Kingdom "Molecular characterization of a novel Leucyl-tRNA from Candida albicans" (THESIS/DISSERTATION)	Aproved
1987/04/23 Concluded	Biologia - Ramo Científico (Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Affiliation

Science

	Category Host institution	Employer
2022/04/01 - Current	Coordinating Researcher (Research)	Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
	Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2022/04/01 - Current	Full Professor (University Teacher)	Universidade de Coimbra Faculdade de Medicina, Portugal
	Universidade de Coimbra Faculdade de Medicina, Portugal
2006/05/31 - 2022/03/31	Associate Professor (University Teacher)	Universidade de Aveiro, Portugal
	Universidade de Aveiro, Portugal
1999/02/16 - 2006/05/31	Assistant Professor (University Teacher)	Universidade de Aveiro, Portugal

2005/03/01 - 2005/08/31	Invited Associate Professor (University Teacher)	Universidade de Kent, United Kingdom

1998/02/16 - 1999/02/15	Invited Assistant Professor (University Teacher)	Universidade de Aveiro, Portugal

Others

	Category Host institution	Employer
2014/12/01 - Current	Coordenador do Consórcio GenomePortugal	Universidade de Aveiro, Portugal

2015/01/01 - 2022/03/31	Diretor do Institute for Biomedicine - iBiMED	Universidade de Aveiro, Portugal

2016/01/01 - 2019	Diretor do Departamento de Ciências Médicas (DCM)	Universidade de Aveiro, Portugal

2014/05/07 - 2015/12/31	Diretor da Secção Autónoma das Ciências da Saúde (SACS)	Universidade de Aveiro, Portugal

2001 - 2004	EMBO Young Investigator	Universidade de Aveiro, Portugal

1995 - 1998	Wellcome Trust Research Fellow	University of Kent, United Kingdom

1992 - 1995	Postdoctoral Research Fellow	University of Kent, United Kingdom

Projects

Contract

	Designation	Funders
2017 - 2022	The Discoveries Centre for Regenerative and Precision Medicine – European Union Horizon 2020-Widespread-2016-2017 739572 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	European Union Ongoing
2018/07/01 - 2021/06/30	Identificação e quantificação dos erros da biossíntese de proteínas à escala proteómica PTDC/BIA-MIB/31238/2017 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2017 - 2020/12/31	Programas Integrados de IC&DT. Projeto Protein aggregation across the lifespan – pAGE CENTRO-45-2015-01-SAICT Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Comissão de Coordenação e Desenvolvimento Regional do Centro Ongoing
2017 - 2020/12/31	Programa de Ações Conjuntas (PAC) : Redes sináticas e abordagens compreensivas de medicina personalizada em doenças neurocomportamentais ao longo da vida – MEDPERSYST POCI-01-0145-FEDER-016428-PAC Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2017/06/01 - 2020/05/30	Laboratório Nacional de Sequenciação e Análise de Genomas PINFRA/22184/2016 Principal investigator Universidade de Aveiro, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018 - 2020	Medicina de Sistemas das doenças cardiovasculares, neurodegenerativas e musculo-esqueléticas - MEDISIS CENTRO-01-0246-FEDER-000018 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Comissão de Coordenação e Desenvolvimento Regional do Centro Ongoing
2016/06/01 - 2019/05/31	A Biologia das modificações do RNA PTDC/BEX-BCM/2121/2014 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015 - 2019	Instituto de Biomedicina de Aveiro – iBiMED UID/BIM/04501/2013 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/04/01 - 2016/03/31	Consequences of reciprocal control of mistranslation during antifungal immunity FCT-ANR/IMI-ANR/0041/2012 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/06/01 - 2013/11/30	Reversion of a genetic code alteration in the human pathogen Candida albicans PTDC/BIA-MIC/099826/2008 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/05/02 - 2013/10/31	Functional genomics of ribosomal infidelity phenotypes associated to human diseases PTDC/SAU-GMG/098850/2008 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2009/11/01 - 2012/10/31	SYBARIS – Finding biomarkers of anti-microbial drug resistance via a systems biology analysis of fungal pathogen interactions with the human immune system SYBARIS/HEALTH-F3-2009-242220 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	European Union Concluded
2009/01/01 - 2011/12/31	Implementation of a national facility for DNA microarrays: phase II PTDC/BIA-BCM/64745/2006 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2009/01/01 - 2011/06/30	Targetting protein synthesis in the apicoplast and cytoplasm of Plasmodium MEPHITIS-FP7-HEALTH-2009-223024 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	European Union Concluded
2005/09/01 - 2009/02/28	mRNA mistranslation in Biological processes RGP0045/2005-C Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Human Frontier Science Program Concluded
2005 - 2008	Impacto do erro de descodificação do mRNA na degeneração e evolução celular POCTI/SAL-MMO/55476/2004 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2008	Estrutura tridimensional dos factores da tradução que medeiam uma alteração ao código genético em Candida albicans POCTI/BIA-PRO/55472/2004 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2008	Estudo da morfogénese e reprodução sexuada induzida por uma alteração ao código genético em Candida albicans POCTI/BIA-MIC/55466/2004 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2008	Estudo molecular do mecanismo de virulência de Candida albicans POCI/SAU-IMI/61591/2004 Principal investigator Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2008	Estudo molecular do mecanismo de virulência de Candida albicans POCI/SAU-IMI/61598/2004 Principal investigator Universidade do Porto Faculdade de Medicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2007	Rede Nacional de Genómica Funcional CONC-REEQ/737/BIO/2005 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2002 - 2005	Developing a DNA chip for diagnostics of infectious diseases CTS 12 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Instituto de Investigação da UA - diagnósticos Concluded
2002 - 2005	Developing new tools for genome analysis POCTI/BME/39030/2001 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2002 - 2005	Developing new tools for genome analysis POCTI/BME/39030/2001	Fundação para a Ciência e a Tecnologia
2001 - 2005	Screening for new Candida albicans virulence factors associated with morphogenesis using proteomics methodologies POCTI/2000/ESP/32942/99 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2001 - 2004	Molecular and structural study of the identity of a novel ser-tRNACAG which mediates a genetic code change in Candida albicans. POCTI/BME/32938/2000 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2001 - 2001	Molecular characterization of non-standard translation in the human pathogen Candida albicans. POCTI/SAU/14123/2001 Principal investigator Universidade de Aveiro, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1999 - 2001	The role of a genetic code alteration in the evolution of novel phenotypes in Candida albicans POCTI/BIA/11139/2002 Principal investigator Universidade de Aveiro Instituto de Biomedicina, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1998 - 2001	Molecular study of the evolutionary pathway of reassignment of the CUG codon in Candida albicans 96/G08693 Principal investigator Universidade de Kent, United Kingdom	Biotechnology and Biological Sciences Research Council Concluded
1999 - 2000	Biologia em Rede para as Escolas e a Comunidade BIOREDE/POSI Principal investigator Universidade de Aveiro, Portugal	Programa Aveiro Cidade Digital Concluded
1995 - 1999	Structural and functional analysis of a novel seryl-tRNACAG from the human pathogen Candida albicans 045548/Z/JRS/SH Principal investigator Universidade de Kent, United Kingdom	Wellcome Trust Concluded
1995 - 1999	Structural and functional analysis of a novel seryl-tRNACAG from the human pathogen Candida albicans 045548/Z/JRS/SH	Wellcome Trust

Other

	Designation	Funders
2001 - 2002	Acções Integradas Luso-Espanholas Acção Nº E-45/01 Principal investigator	Concluded

Outputs

Publications

Book	Fernando Regateiro; Sofia L. Marques; Sonya Neto; Miguel Pinheiro; João Manuel Santos de Miranda; Manuel Santos; Gabriela Moura. DNA Sequencing - NGS: Good Practice Manual. 2023. 10.14195/978-989-26-2525-6 Soares, A.R.; Pereira, P.M.; Santos, M.A.S.. Next-generation sequencing of miRNAs with Roche 454 GS-FLX technology: Steps for a successful application. 2012. 10.1007/978-1-61779-427-8_13 Moura, G.; Pinheiro, M.; Freitas, A.V.; Oliveira, J.L.; Santos, M.A.S.. Computational and statistical methodologies for ORFeome primary structure analysis. 2007. 10.1385/1-59745-514-8:449 Pinheiro, M.; Oliveira, J.L.; Santos, M.A.S.; Rocha, H.; Cardoso, M.L.; Vilarinho, L.. NeoScreen: A software application for MS/MS newborn screening analysis. 2004.
Book chapter	do Céu Santos, Maria; Santos, Manuel. "Structural and molecular features of non-standard genetic codes". In Codon Evolution, 258-272. Oxford University Press, 2012. Published • 10.1093/acprof:osobl/9780199601165.003.0017 Gomes, A.C.; Moura, Gabriela; Santos, Manuel. "The Genetic Code of the Candida CTG Clade". In Candida and Candidiasis, Second Edition, 45-55. American Society of Microbiology, 2012. Published • 10.1128/9781555817176.ch4 Santos, Manuel; Soares, Ana Raquel. "Computational Tools for Identification of microRNAs in Deep Sequencing Data Sets". In Computational Biology and Applied Bioinformatics. InTech, 2011. 10.5772/21173 Lousado, José Paulo; Oliveira, José Luis; Moura, Gabriela; Santos, Manuel; Lousado, J.P.; Oliveira, J.L.. "An Application for Studying Tandem Repeats in Orthologous Genes". In Advances in Intelligent and Soft Computing, 109-115. Springer Berlin Heidelberg, 2010. Published • 10.1007/978-3-642-13214-8_14 Moura, Gabriela; Lima-Costa, T.; Carreto, L.; Gomes, A.C.; Santos, Manuel. "Molecular evolution of the Candida genetic code". In Candida: comparative and functional genomics. 2007. Published Adelaide Valente Freitas; Miguel Pinheiro; José Luis Oliveira; Moura, Gabriela; Santos, Manuel. "A new limiting distribution for a statistical test for the homogeneity of two multinomial populations". Wolfgang Urfer M. Antónia Amaral Turkman, 2005. Santos, Manuel; Tuite, Mick F.. "Extant Variations in the Genetic Code". In The Genetic Code and the Origin of Life, 183-200. Springer US, 2004. Published • https://doi.org/10.1007/0-387-26887-1_12 O´Sullivan, J.M.; Santos, Manuel; Tuite, M.F.. "Standard and non-standard mRNA decoding in Candida albicans". 279-292. ASM Press Washington, 2002. Published Hartley, Alan D.; Santos, Manuel; Colthurst, David R.; Tuite, Michael F.. "Preparation and Use of Yeast Cell-Free Translation Lysate". In Yeast Protocols, 249-258. Humana Press, 1996. Published • 10.1385/0-89603-319-8:249 Santos, Manuel; Keith, Gerad; Tuite, Mick F.. "Aberrant mRNA Decoding in the Dimorphic Yeast Candida Albicans". In Protein Synthesis and Targeting in Yeast, 111-121. Springer Berlin Heidelberg, 1993. Published • 10.1007/978-3-642-84921-3_11
Conference paper	Farkas, Z.; Bodi, Z.; Nevozhay, D.; Kalapis, D.; Lazar, V.; Csoergo, B.; Nyerges, A.; et al. "Phenotypic heterogeneity guides adaptive evolution". 2015. Published Weil, T.; Santamaria, R.; Lee, W.; Rung, J.; Tocci, N.; Simões, J.; Bezerra, A.R.; et al. "A genetic code alteration accelerates the acquisition of antifungal drug resistance in Candida albicans". Paper presented in A genetic code alteration accelerates the acquisition of antifungal drug resistance in Candida albicans, 2015. Published Carvalho, J.; van Grieken, N.; Pereira, P.M.; Diosdado, B.; Santos, Manuel; Meijer, G.; Buffart, T.E.; et al.. "Lack of microRNA-101 causes E-catherin functional deregulation through EZH2 upregulation in the intestinal gastric cancer". 2012. Ferreira, R.M.; Leite, M.; Carreto, L.; Santos, Manuel; Figueiredo, C.. "Gene expression profiling of gastric cells infected by Helicobacter pylori". 2011. Published Bordeira-Carriço, R.; Pego, A.P.; Seruca, R.; Santos, Manuel; Oliveira, C.. "Disease-causing truncating mutations: is reversion possible?". 2011. Published Ribeiro, A.S.; Carreto, L.C.; Albergaria, A.; Sousa, B.; Ricardo, S.; Milanezi, F.; Seruca, R.; et al. "514 Co-expression of E-and P-cadherin in breast cancer: role as an invasion suppressor or as an invasion promoter?". 2010. Published Lousado, J.P.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel. "Análise da evolução de repetições de codões e de aminoácidos em dados biológicos". Paper presented in CISTI 2010 – 5th Iberian Conference on Information Systems and Technologies, 2010. Published Lousado, J.P.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel. "An application for study tandem repeats in orthologous genes". 2010. Silva, A.; Paredes, J.; Santos, Manuel; Ludovico, P.. "Acetic acid-induced apoptosis in Saccharomyces cerevisiae involves global translation impairment". Paper presented in MicroBiotec, 2009. Published Nobre, A.; Pereira, P.M.; Santos, Manuel; da Costa, M.S.. "Expression analysis of genes involved in trehalose pathways in Rubrobacter xylanophilus". Paper presented in MicroBiotec09, 2009. Published Lousado, J.P.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel; Moura, G.R.; Santos, M.A.S.. "Analysing the evolution of repetitive strands in genomes". 2009. Published • 10.1007/978-3-642-02481-8_159 Freitas, A.; Afreixo, V.; Pinheiro, M.; Oliveira, J.L.; Santos, Manuel. "Uma avaliação da performance do algoritmo de bi-classificação ISA-mediana". Paper presented in JOCLAD 2009 – XVI Jornadas de Classificação e Análise de Dados, 2009. Published Pinheiro, Miguel; Oliveira, José L.; Moura, Gabriela; Santos, Manuel. "Studying the Evolution of Codon Context in Conserved Gene Sequences". Paper presented in 2008 International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, 2008. Published • 10.1109/biotechno.2008.18 Lousado, José P.; Moura, Gabriela; Santos, Manuel; Oliveira, José Luis. "Exploiting Codon-Triplets Association for Genome Primary Structure Analysis". Paper presented in 2008 International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, 2008. Published • 10.1109/biotechno.2008.21 Arrais, Joel P.; Carreto, Laura; Santos, Manuel; Oliveira, José L.. "A Microarray Information Database". Paper presented in 2008 International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, 2008. Published • 10.1109/biotechno.2008.22 Lousado, J.P.; Moura, Gabriela; Santos, Manuel; Oliveira, J.L.. "GeneSplit-uma aplicação para o estudo de associações de codões e de aminoácidos em ORFeomas". Paper presented in Iberian Conference on Information Systems and Technologies, CISTI, 2008. Published Pereira, P.M.; Soares, Ana Raquel; Marques, J.P.; Santos, Manuel. "Differential expression of miRNAs in human cervical cancer". 2008. Published V. Afreixo; A. Freitas; M. Pinheiro; J. L. Oliveira; Moura, Gabriela; Santos, Manuel. "Exploiting a Biclustering algorithm in ORFeome analysis". Paper presented in 2007 VLDB Workshop on Data Mining in Bioinformatics, 2007. Published Pereira, L.; Machado, S.; Ramos, P.; Alemão, F.; Gomes, P.; Sousa, S.; Santos, Manuel; et al. "Comparison of Saccharomyces cerevisiae populations from different appellations of origin and grape varieties by microsatellite analysis". Paper presented in Congresso Nacional Micro'07 Biotec'07 - XXXIII JPG, 2007. Published Duarte, J.; Freitas, A.; Pinheiro, M.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel. "ISA: um algoritmo de biclassificação?". Paper presented in XIV Congresso da Sociedade Portuguesa de Estatística, 2007. Published Freitas, A.; Duarte, J.; Pinheiro, M.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel. "Homo sapiens vs Pan troglodytes: quão diferentes são?". Paper presented in XIV Congresso da Sociedade Portuguesa de Estatística, 2007. Published Freitas, A.; Pinheiro, M.; Afreixo, V.; Duarte, J.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel; et al. "A median-based iterative signature algorithm". Paper presented in 56th session of the International Statistical Institute, 2007. Published Pinheiro, M.; Afreixo, V.; Moura, Gabriela; Freitas, A.; Santos, Manuel; Oliveira, J.L.. "Statistical, computational and visualization methodologies to unveil gene primary structure features". 2006. Published Arrais, J.; Silva, L.; Rodrigues, M.; Carreto, L.; Oliveira, J.L.; Santos, Manuel. "Why another microarrays LIMS". Paper presented in EMBEC’05 – The 3rd European Medical and Biological Engineering Conference, 2005. Published Pinheiro, M.; Oliveira, J.L.; Santos, Manuel; Rocha, H.; Cardoso, M.L.; Vilarinho, L.. "Results of a biomedical application in newborn screening programs". Paper presented in EMBEC’05 – The 3rd European Medical and Biological Engineering Conference, 2005. Published Freitas, A.; Pinheiro, M.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel; Adelaide Valente Freitas; Miguel Pinheiro; José Luis Oliveira. "A new limiting distribution for the statistic test for the homogeneity of two multinomial populations". Paper presented in Workshop on Statistics in Genomics and Proteomics, 2005. Published Miguel Pinheiro; J Oliveira; Santos, Manuel; H Rocha; M Cardoso; L Vilarinho. "A computer-based solution for screening of inherited metabolic diseases". 2004. Published García-Remesal, M.; Maojo, V.; Billhardt, H.; Crespo, J.; Alonso-Calvo, R.; Pérez, D.; Martín, F.; et al. "Designing new methodologies for integrating biomedical information in clinical trials". Paper presented in EuroMISE 2004, 2004. Published • 10.1109/cbms.2010.6042631 Santos, Manuel; Beltrão, P.; Almeida, R.; Massey, S.; Garey, J.; Moura, Gabriela. "Comparative evolutionary genomics of CUG reassignment in Candida species". Paper presented in XXIst International Conference on the Yeast Genetics and Molecular Biology, 2003. Published Oliveira, I.; Oliveira, J.L.; Santos, Manuel; Martin-Sanchez, F.; Pereira, A.S.. "On the requirements of biomedical information tools for health applications: the INFOGENMED case study". Paper presented in BioEng’2003 – 7th Portuguese Conference on Biomedical Engineering, 2003. Published Silva, R.; Gomes, A.C.; Santos, J.S.; Perrot, M.; Boucherie, H.; Santos, Manuel. "On the engineering of a genetic code change in yeast". 2003. Santos, J.M.; Silva, R.M.; Branco, J.O.; Santos, Manuel; J.M. Santos; R.M. Silva; J.O. Branco. "The global impact of ambiguous mRNA decoding on gene expression". Paper presented in 27th Meeting of the FEBS, 2001. Published Miranda, I.; Moura, Gabriela; Gomes, A.C.; Santos, Manuel. "Codon usage in Candida albicans". 2001. Published Moura, Gabriela; Miranda, I.; Gomes, A.C.; Santos, Manuel. "Non-standard translation and genetic code ambiguity in Candida albicans". 2001. J. M. O'sullivan; E. Chukeatirote; S. Massey; B. Davenport; P. J. Brown; Santos, Manuel; M. F. Tuite. "The evolution of CUG reassignment in Candida albicans". 2000. Published • 10.1042/bst028a186a
Conference poster	Lopes, E.; Oliveira, C.; Bezerra, A.R.; Santos, Manuel. "Identification of molecules and pathways regulating mistranslation in Candida albicans". Paper presented in II Simpósio de Pós-Graduação em Biomedicina, 2016. Santos, M.; Varanda, A.S.; Fidalgo, A.; Almeida, G.M.; Oliveira, C.; Santos, Manuel. "Misreading tRNAs contribute to lung cancer development and increase resistance to conventional chemotherapy". Paper presented in II Simpósio de Pós-Graduação em Biomedicina, 2016. Lopes, E.; Oliveira, C.; Bezerra, A.R.; Santos, Manuel. "Identification of molecules and pathways regulating mistranslation in Candida albicans". Paper presented in XL Jornadas Portuguesas de Genética, 2016. Guimarães, A.R.; Bezerra, A.R.; Santos, Manuel. "Codon ambiguities as a mechanism to alter the genetic code in Saccharomyces cerevisiae". Paper presented in XL Jornadas Portuguesas de Genética, 2016. Pereira, P.M.; Santos, Manuel; Varanda, A.S.; Carvalho, J.; Azevedo, M.; Mateus, D.D.; Mendes, N.; et al. "Contribution of misreading Serine tRNAs to tumor growth in vivo". Paper presented in European Society of Human Genetics Conference, 2016. Lopes, E.; Oliveira, C.; Bezerra, A.R.; Santos, Manuel. "Identification of molecules and pathways regulating mistranslation in Candida albicans". Paper presented in 10th International Symposium on Aminoacyl-tRNA Synthetases, 2015. Oliveira, C.; Lopes, E.; Santos, Manuel; Bezerra, A.R.. "Identification of molecules and pathways regulating mistranslation in Candida albicans". Paper presented in iMed 7.0 Conference, 2015. Fidalgo, A.; Santos, Manuel; Varanda, A.S.; Santos, M.A.S.; Soares, Ana Raquel. "The contribution of tRNA pool deregulation for the acquisition of a malignant phenotype". Paper presented in iMed 7.0 Conference, 2015. Lopes, E.; Oliveira, C.; Bezerra, A.R.; Santos, Manuel. "Candida albicans gene mistranslation as a modulator of host-pathogen interactions and pathogenesis". Paper presented in XXXIX Jornadas Portuguesas da Genética, 2015. Lopes, E.; Oliveira, C.; Bezerra, A.R.; Santos, Manuel. "Identification of molecules and pathways regulating mistranslation in Candida albicans". Paper presented in Biochemistry Day, 2015. Oliveira, C.; Lopes, E.; Santos, Manuel; Bezerra, A.R.. "Regulation of genetic code ambiguity in the human pathogen Candida albicans". Paper presented in VII Jornadas de Genética e Biotecnologia, 2015. Fidalgo, A.; Santos, Manuel; Varanda, A.S.; Santos, M.A.S.. "Study of proteotoxic stress in a mistranslating cell line versus a cancer cell line". Paper presented in VII Jornadas de Genética e Biotecnologia, 2015. Pereira, P.M.; Santos, Manuel; Varanda, A.S.; Carvalho, J.; Mendes, N.; Oliveira, P.; Teixeira Pinto, M.; et al. "Expression of misreading Serine tRNAs in mammalian cells accelerate tumor growth in vivo". Paper presented in 1st Aspic International Congress, 2014. Bezerra, A.R.; Santos, Manuel. "Proteomic and metabolic analysis of mistranslating Candida albicans strains". Paper presented in Gene translation: fidelity and quality control, 2013. Dias, A.R.; Santos, Manuel. "The role of mistranslation on the metabolim of lipids in yeast". Paper presented in Gene translation: fidelity and quality control, 2013. Reverendo, M.; Santos, Manuel. "Genome mistranslation leads to proteome instability through protein aggregation and accumulation of oxidative stress in zebrafish". Paper presented in Gene translation: fidelity and quality control, 2013. Simões, J.; Santos, Manuel. "Unveiling the mechanism behind C. albicans CUG ambiguity fluctuation". Paper presented in Gene translation: fidelity and quality control, 2013. Varanda, A.S.; Santos, Manuel. "Cellular responses triggered by mistranslation in HEK293 cells". Paper presented in Gene translation: fidelity and quality control, 2013. Franco-Duarte, R.; Carreto, L.; Mendes, I.; Cambon, B.; Dequin, S.; Santos, Manuel; Casal, M.; Schuller, D.. "Intra-strain phenotypic and genomic variability of the commercial Saccharomyces cerevisiae strains Zymaflore VL1 recovered from vineyard environments". Paper presented in Molecular Biology in Portugal and EMBL, 2013. 10.1063/1.4973143 Soares, Ana Raquel; Fernandes, N.; Reverendo, M.; Santos, Manuel. "A new class of zebrafish tissue-specific non-coding RNAs derived from tRNAs with miRNA-like features". Paper presented in Young EMBO Scientists’ forum, 2013. Silva, A.; Sárkány, Z.; Carvalho, V.; Moreira, M.; Santos, Manuel; Pereira, P.J.B.; Macedo-Ribeiro, S. "Is there a link between code ambiguity and virulence in the human pathogen, Candida albicans?". Paper presented in 15th FEBS Advanced Lecture Course on Human Fungal Pathogens, 2013. Simões, J.; Bezerra, A.R.; Weil, T.; Santos, Manuel. "The Candida albicans proteome tolerates generalized genetic code ambiguity". Paper presented in XXIV tRNA Conference, 2012. Cardoso, R.; Pinto, C.; Sousa, S.; Pinheiro, M.; Egas, C.; Santos, Manuel; Gomes, A.. "Endogenous microbial communities in wine fermentations". Paper presented in EMBO Conference Series “Experimental Approaches to Evolution and Ecology using Yeast”, 2012. Mélo, A.; Pereira, A.R.; Sousa, S.; Rocha, S.; Coimbra M.; Santos, Manuel; Gomes, A.. "Yeast biodiversity in the vines: unveiling their phenotypic and metabolic traits". Paper presented in EMBO Conference Series “Experimental Approaches to Evolution and Ecology using Yeast”, 2012. Schuller, D.; Pereira, L.; Franco-Duarte, R.; Ramos, P.; Alemão, M.F.; Gomes, P.; Sousa, S.; et al. "Microsatellite analysis reveals populational structures of Saccharomyces cerevisiae strains from different appellations of origin and grape varieties". Paper presented in EMBO Workshop on “Evolutionary and Environmental Genomics of Yeasts”, 2012. Carreto. L.; Schuller, D.; Santos, Manuel. "Genome and transcriptome variability in a natural yeast population". 2012. Sarkany, Z.; Fernandes, V.; Santos, Manuel; Pereira, P.J.B.; Macedo-Ribeiro, S.. "Is there a link between genetic code ambiguity and virulence in Candida albicans". Paper presented in FEBS International Workshop “New Developments in RNA Biology”, 2012. Reverendo, M.; Soares, Ana Raquel; Santos, Manuel. "Ribosome mistranslations produce reactive oxygen species and increase protein aggregation in zebrafish". Paper presented in FEBS International Workshop “New Developments in RNA Biology”, 2012. Soares, Ana Raquel; Reverendo, M.; Pinheiro, M.; Santos, Manuel. "Identification of Dicer-dependent tRNA derived fragments in zebrafish". Paper presented in FEBS International Workshop “New Developments in RNA Biology”, 2012. J. Simões; A. Bezerra; T. Weil; Santos, Manuel. "Characterization of Candida albicans strains with a new induced ambiguity". 2012. Silva, A.; Sampaio-Marques, B.; Santos, Manuel; Ludovico, P.. "HSP90: endogenous modulators of yeast acetic acid-induced apoptotic cell death". Paper presented in MicroBiotec’11, 2011. Weil, T.; Bezerra, A.R.; Simões, J.; Santos, Manuel. "Genetic code ambiguity accelerates evolution of drug resistance in Candida albicans". Paper presented in FINSysB Conference – Candida Infection Biology, 2011. Paredes, J.; Santos, Manuel. "Genome wide gene mistranslation unveils the celular signatures of proteotoxic stress in yeast". Paper presented in 5th International Congress on Stress Response in Biology and Medicine, 2011. Santos, Manuel. "The yeast responses to aberrant protein synthesis". Paper presented in EMBO Conference Series – The Biology of Molecular Chaperones, 2011. Simões, J.M.S.; Bezerra, A.R.; Weil, T.; Santos, Manuel; J. Simões; A. Bezerra; T. Weil. "Characterization of Candida albicans strains with non-CUG ambiguity". Paper presented in 4th FEBS Advanced Lecture Course, Human Fungal Pathogens, Molecular Mechanisms of Host-Pathogen Interactions and Virulence, 2011. Varanda, A.S.; Duarte, C.B.; Santos, Manuel. "Cellular responses to aberrant protein synthesis in human fibroblasts". Paper presented in XXXVI Jornadas Portuguesas de Genética, 2011. Araújo, A.R.; Bezerra, A.R.; Simões, J.; Weil, T.; Santos, Manuel. "Antifungal drug resistance in mistranslating yeast". Paper presented in XXXVI Jornadas Portuguesas de Genética, 2011. Reverendo, M.; Soares, Ana Raquel; Santos, Manuel. "Impact of mRNA mistranslation on zebrafish development". Paper presented in XXXVI Jornadas Portuguesas de Genética, 2011. Fernandes, J.; Frommlet, J.; Moura, Gabriela; Santos, Manuel. "Testing of a beta-galactosidase reporter system for the in vivo study of codon context effects on translation". Paper presented in XXXVI Jornadas Portuguesas de Genética, 2011. Moura, Gabriela; Pinheiro, M.; Freitas, A.; Oliveira, J.L.; Frommlet, J.C.; Santos, Manuel. "Codon-pair context biases are conserved in coding sequences of bacteria, archaea and eukaryotes". Paper presented in XVII Congresso Nacional de Bioquímica, 2010. Bezerra, A.R.; Simões, J.; Weil, T.; Santos, Manuel. "Phenotypic profile of Candida albicans strains with an artificially altered genetic code". Paper presented in XVII Congresso Nacional de Bioquímica, 2010. Simões, J.; Bezerra, A.R.; Weil, T.; Santos, Manuel. "Phenotypic characterization of genome mistranslation in the human pathogen Candida albicans". Paper presented in XVII Congresso Nacional de Bioquímica, 2010. Gomes, A.C.; Moura, Gabriela; Farabaugh, P.; Santos, Manuel. "The impact of environmental stress on genome translational fidelity". Paper presented in XVII Congresso Nacional de Bioquímica, 2010. Ana S Ribeiro; Laura C Carreto; André Albergaria; Bárbara Sousa; Sara Ricardo; Fernanda Milanezi; Raquel Seruca; et al. "Co-expression of E- and P-cadherin in breast cancer : role as an invasion suppressor or as an invasion promoter?". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, 2010. https://doi.org/10.1186/1753-6561-4-S2-P47 Carreto, L.; Santos, Manuel. "Mistranslation of the genetic code destabilizes the yeast genome". Paper presented in EMBO Conference Series – Experimental Approaches to Evolution and Ecology in Yeast, 2010. Santos, M.; Santos, Manuel. "Evolution of genome translation rules in yeasts". Paper presented in EMBO Conference Series – Experimental Approaches to Evolution and Ecology in Yeast, 2010. Pereira, P.M.; Marques, J.P.; Soares, Ana Raquel; Carreto, L.; Santos, Manuel. "Tackling miRNA expression variability in human cervical tissues". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010. Santos, M.C.G.; Santos, Manuel. "CUN codons are differentially decoded in yeasts". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010. Paredes, J.A.; Carreto, L.; Costa, T.L.; Moura, Gabriela; Santos, Manuel. "The transcriptional responses to genome mistranslation in yeast". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010. Franco-Duarte, R.; Gomes, A.C.; Santos, Manuel; Sousa, B.; Schuller, D.. "Microfluidics-based automated genotyping of Saccharomyces cerevisiae strains by interdelta sequence typing – an interlaboratory comparison". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010. Schuller, D.; Cardoso, F.; Gomes, P.; Sousa, S.; Gomes, A.C.; Santos, Manuel; Casal, M.. "Comparison of Saccharomyces cerevisiae populations from different appellations of origin and grape varieties by microsatellite analysis". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010. P. Gaspar; J.L. Oliveira; J. Frommlet; Moura, Gabriela; Santos, Manuel. "A gene multi-optimization tools as novel approach to heterologous expression". Paper presented in 14th International Conference on Research in Computational Molecular Biology (RECOMB 2010), 2010. Gomes, A.C.; Santos, Manuel. "Ambiguous decoding of the CUG codon creates a statistical proteome in the human pathogen Candida albicans". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Mateus, D.D.; Paredes, J.A.; Español, Y.; Pouplana, L.R.; Santos, Manuel. "Molecular reconstruction of a fungal genetic code alteration in yeast". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Simões, J.; Bezerra, A.R.; Rocha, R.; Weil, T.; Pouplana, L.R.; Santos, Manuel. "Regulation of genetic code ambiguity in human pathogen Candida albicans". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Soares, Ana Raquel; Reverendo, M.; Pinheiro, M.; Pereira, P.; Santos, Manuel. "Parallel DNA pyrosequencing unveils a novel class of small non-coding RNAs derived from tRNAs in zebrafish". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Bordeira-Carriço, R.; Santos, Manuel; Pêgo, A.P.; Seruca, R.; Oliveira, C.. "Suppressor-tRNAs: a tool to correct mutations in the human CDH1 gene?". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Rocha, R.; Pereira, P.J.B.; Santos, Manuel; Macedo-Ribeiro, S.. "Crystal structures of the Candida albicans seryl-tRNA synthetase provide new clues to understand the evolution of a fungal genetic code alteration". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Reverendo, M.; Soares, Ana Raquel; Santos, Manuel. "Induced serine mistranslation in zebrafish". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Paredes, J.A.; Carreto, L.; Santos, Manuel. "Mistranslation causes major genomic alterations in yeast". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Santos, C.H.; Paredes, J.; Santos, Manuel; Goodfellow, B.J.. "NMR metabolic profiling of Saccharomyces cerevisiae high high levels of mRNA mistranslation". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Lima-Costa, T.; Paredes, J.A.; Reverendo, M.; Rondeau. C.; Desjardins, M.; Santos, Manuel. "The cellular responses to tRNA misreading in yeast". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Gomes, A.C.; Moura, Gabriela; Farabaugh, P.; Santos, Manuel. "The impact of environmental stress on the accuracy of tRNA decoding". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. J. Frommlet; P. Gaspar; M. Pinheiro; J.L. Oliveira; A.C. Gomes; Moura, Gabriela; Santos, Manuel. "Integrating tRNA abundance, codon-usage, codon-context and functional rare codon data in de novo synthesis of Plasmodium falciparum genes for optimal expression in Escherichia coli". Paper presented in 23rd tRNA Workshop (tRNA 2010), 2010. Soares, Ana Raquel; Reverendo, M.; Pereira, P.; Santos, Manuel. "Identification of novel zebrafish microRNAs by high throughput sequencing and target validation of novel dre-miR-2188". Paper presented in V Meeting on RNA research in Portugal (RNA2009), 2009. Santos, M.; Santos, Manuel. "New leucine tRNAs explain divergent CUN decoding rules in yeasts". Paper presented in V Meeting on RNA research in Portugal (RNA2009), 2009. Bordeira-Carriço, R.; Santos, Manuel; Pêgo, A.P.; Seruca, R.; Oliveira, C.. "Artificial mini-gene: a new model to study CDH1 mutations". Paper presented in V Meeting on RNA research in Portugal (RNA2009), 2009. Bezerra, A.R.; Simões, J.; Santos, Manuel. "New tools for studying the Candida albicans genetic code". Paper presented in Third FEBS Advanced Lecture Course “Human Fungal Pathogens”, 2009. Simões, J.; Bezerra, A.R.; Santos, Manuel. "CUG ambiguity in C.albicans is remodelled by environmental factors". Paper presented in Third FEBS Advanced Lecture Course “Human Fungal Pathogens”, 2009. Simões, J.; Bezerra, A.R.; Santos, Manuel. "CUG ambiguity in C.albicans is remodelled by environmental factors". 2009. Santos, S.; Sousa, S.; Simões, J.; Martins, E.; Reverendo, M.; Gomes, A.C.; Santos, Manuel. "High throughput phenotypic screening unveils important hidden phenotypic diversity in wild type yeast". Paper presented in XVI Congresso Nacional de Bioquímica, 2008. Carreto, L.; Schuller, D.; Santos, Manuel; Carreto. L.. "Genome and transcriptome variability in yeast". Paper presented in XVI Congresso Nacional de Bioquímica, 2008. Rocha, R.; Pereira, P.J.B.; Santos, Manuel; Macedo-Ribeiro, S.. "Snapshots of a canonical seryl-tRNA synthetase with an atypical ATP binding mode". Paper presented in aaRS2008, International Conference on Aminoacyl-tRNA Synthetases, 2008. Mateus, D.; Paredes, J.; Rocha, R.; Santos, Manuel. "In vivo molecular characterization of a hybrid Candida albicans tRNA(CAG)Ser". Paper presented in aaRS2008, International Conference on Aminoacyl-tRNA Synthetases, 2008. Gomes, C.; Moura, Gabriela; Oliveira, J.L.; Pinheiro, M.; Farabaugh, P.J.; Kramer, E.; Santos, Manuel. "The role of biased codon-context on mRNA decoding error in vivo in yeast". Paper presented in Translational Control, Cold Spring Harbor Laboratory, 2008. Lima-Costa, T.; Paredes, J.; Rondeau, C.; Desjardins, M.; Santos, Manuel. "mRNA mistranslation upregulates autophagy and is an important source of protein aggregation in yeast". Paper presented in RNA 2008 – 13th Annual Meeting of the RNA Society, 2008. Santos, Manuel; Gomes, A.. "mRNA misreading generates proteome and phenotypic diversity in the human pathogen Candida albicans". Paper presented in RNA 2008 – 13th Annual Meeting of the RNA Society, 2008. Ceppi, M.; Pereira, P.; Clavarino, G.; Schmidt, E.K.; Dejardins, M.; Santos, Manuel; PIERRE, Philippe. "Investigating the role of translation in dendritic cell and immune functions". Paper presented in HFSP – 8th Annual Awardees Meeting, 2008. Moura, Gabriela; Pinheiro, M.; Freitas, A.; Oliveira, J.L.; Santos, Manuel. "Codon context rules governing mRNA decoding accuracy and gene evolution". Paper presented in HFSP – 8th Annual Awardees Meeting, 2008. Santos, Manuel. "The evolution of a genetic code alteration in Candida spp.". Paper presented in ASM Conferences – 9th Candida and Candidiasis, 2008. Santos, M.; Pinheiro, M.; Santos, Manuel. "Candida albicans as a model system to study genetic code alterations at genome level". Paper presented in ASM Conferences – 9th Candida and Candidiasis, 2008. Santos, M.; Santos, Manuel. "A tRNomics approach to understand a genetic code change". Paper presented in IV National RNA Meeting (RNA 2007), 2007. Soares, Ana Raquel; Pereira, P.M.; Santos, Manuel. "High throughput sequencing of zebrafish microRNAs". Paper presented in IV National RNA Meeting (RNA 2007), 2007. Pereira, P.M.; Soares, Ana Raquel; Marques, J.P.; Santos, Manuel. "Global microRNA profiling in human cervical cancer". Paper presented in MicroRNAs Europe 2007 Meeting, 2007. Soares, Ana Raquel; Pereira, P.M.; Santos, Manuel. "Diversity of miRNAs in zebrafish using massive parallel sequencing". Paper presented in MicroRNAs Europe 2007 Meeting, 2007. Carreto, L.; Eiriz, F.; Santos, Manuel. "Comparative gene expression profiling of wild type S. cerevisiae strains". Paper presented in ESF-EMBO Symposium on Comparative Genomic of Eukaryotic Microorganisms, 2007. M.C. Santos; M. Pinheiro; J.L. Oliveira; Santos, Manuel. "Comparative tRNomics of a genetic code alteration". Paper presented in ESF-EMBO Symposium on Comparative Genomics of Eukaryotic Microorganisms: Eukaryotic Genome Evolution, 2007. Gomes, C.; Moura, Gabriela; Gomes, A.C.; Oliveira, J.L.; Pinheiro, M.; Freitas, A.; Santos, Manuel. "The role of codon-context on mRNA decoding error in vivo in yeast". Paper presented in EMBO Conference on Protein Synthesis and Translational Control, 2007. Lima-Costa, T.; Paredes, J.; Silva, R.; Santos, Manuel. "Mistranslation in yeast cells as an important source of P-bodies and protein aggregates". Paper presented in EMBO Conference on Protein Synthesis and Translational Control, 2007. Paredes, J.; Silva, R.; Carreto, L.; Costa, T.; Santos, Manuel. "The cellular response to mRNA mistranslation in yeast". Paper presented in EMBO Conference on Protein Synthesis and Translational Control, 2007. Pereira, P.M.; Soares, Ana Raquel; Marques, J.P.; Santos, Manuel. "MicroRNA expression profiling in cervical cancer". Paper presented in EMBO Conference on Protein Synthesis and Translational Control, 2007. Gomes, A.C.; Paredes, J.; Miranda, I.; Silva, R.; Santos, Manuel. "Mistranslation drives evolution of genetic code alterations". Paper presented in EMBO Conference on Protein Synthesis and Translational Control, 2007. Santos, Manuel. "mRNA mistranslation in biological systems". Paper presented in NKI Seminar, 2007. Gomes, A.C.; Sousa, S.; Carreto, L.; Gomes, F.; Egas, C.; Santos, Manuel. "The Bairrada-wine microbiome". Paper presented in MicroBiotec’2007, 2007. Carreto, L.; Eiriz, M.F.; Santos, Manuel. "Yeast gene expression profiling during alcoholic fermentation". Paper presented in MicroBiotec’2007, 2007. Paredes, J.; Silva, R.M.; Carreto, L.; Costa, T.L.; Santos, Manuel. "Transcriptional response to mRNA mistranslation in yeast". Paper presented in MicroBiotec’2007, 2007. A. Freitas; V. Afreixo; M. Pinheiro; J.L. Oliveira; Moura, Gabriela; Santos, Manuel. "A median-based iterative signature algorithm". 2007. Gomes, C.; Moura, Gabriela; Gomes, A.C.; Oliveira, J.L.; Pinheiro, M.; Valente, A.; Santos, Manuel. "The role of codon context on mRNA decoding error in vivo in yeast". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Carreto, L.; Pereira, P.M.; Arrais, J.; Oliveira, J.L.; Santos, Manuel. "National facility for DNA microarrays". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Carreto, L.; Silva, R.; Arrais, J.; Oliveira, J.L.; Santos, Manuel. "Implementation of a DNA microarray platform for yeast transcript profiling and genotyping". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Pereira, P.M.; Carreto, L.; Santos, Manuel. "A DNA microarray platform for microRNA expression profiling". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Silva, R.M.; Lima-Costa, T.; Paredes, J.A.; Santos, Manuel. "The role of mRNA mistranslation on cell degeneration and aging". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Lousado, J.P.F.; Moura, Gabriela; Pinheiro, M.; Oliveira, J.L.; Santos, Manuel; J.P. Lousado; M. Pinheiro; J.L. Oliveira. "Large scale comparative genomics of codon context". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Mateus, D.; Paredes, J.; Santos, Manuel; Rocha, R.; Gomes, A.C.; Macedo-Ribeiro, S.. "Molecular characterization of the identity elements of a Candida albicans tRNA(CAG)Ser". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Miranda, I.; Rocha, R.; Santos, S.; Santos, Manuel. "Genetic code ambiguity as a phenotypic diversity generator in Candida albicans". Paper presented in III Encontro Nacional de Biologia do RNA (RNA 2006), 2006. Rocha, R.; Mateus, D.; Gomes, A.C.; Macedo-Ribeiro, S.; Santos, Manuel. "Structural characterization of a novel genetic code alteration". 2006. Gomes, A.C.; Miranda, I.; Thomas, B.; Akoulitchev, A.; Santos, Manuel. "The human pathogen Candida albicans has a statistical proteome". 2006. Carreto, L.; Silva, R.; Arrais, J.; Oliveira, J.L.; Santos, Manuel. "Implementation of a DNA microarray platform for yeast transcript profiling and genotyping". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. Pereira, P.M.; Carreto, L.; Santos, Manuel. "A DNA microarray platform for microRNA expression profiling". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. Paredes, J.A.; Silva, R.M.; Lima-Costa, T.; Santos, Manuel. "A new model system to study wRNA mistranslation in yeast". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. Gomes, A.C.; Miranda, I.; Thomas, B.; Akoulitchev, A.; Santos, Manuel. "The human pathogen Candida albicans has a statistical proteome". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. Moura, Gabriela; M. Pinheiro; C. Gomes; A. Freitas; J.L. Oliveira; Santos, Manuel. "Large scale comparative codon context analysis unveils novel rules governing gene evolution". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. C. Gomes; Moura, Gabriela; A.C. Gomes; J.L. Oliveira; M. Pinheiro; A. Freitas; Santos, Manuel. "The role of codon context on mRNA decoding error in vivo in yeast". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. P.R. Almeida; L. Carreto; J.L. Oliveira; Santos, Manuel. "Software-assisted design of probes for SNPs detection using oligonucleotide microarrays: applications in a case study". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. J. Arrais; L. Carreto; H. Pais; F. Lopes; Santos, Manuel; J.L. Oliveira. "A laboratory information management system for microarray data storage, sharing and analysis". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. M. Pinheiro; Moura, Gabriela; A. Freitas; Santos, Manuel; J.L. Oliveira. "A bioinformatics system to analyze sequences at a genomic scale". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. A. Freitas; L. Ferreira; J. Duarte; M. Pinheiro; J.L. Oliveira; Moura, Gabriela; Santos, Manuel. "Homo sapiens vs Pan troglodytes: how different are they?". Paper presented in XV Congresso Nacional de Bioquímica (CNB2006), 2006. J.P. Lousado; Moura, Gabriela; M. Pinheiro; J.L. Oliveira; Santos, Manuel. "Large scale comparative genomics of codon context". 2006. Mateus, D.; Paredes, J.; Santos, Manuel. "Molecular characterization of the identity elements of a Candida albicans tRNA(CAG)Ser". 2006. Rocha, R.; Mateus, D.; Gomes, A.C.; Macedo-Ribeiro, S.; Santos, Manuel. "Structural characterization of a novel genetic code alteration". 2006. Pereira, P.M.; Carreto, L.; Santos, Manuel. "Implementation of a microRNA expression profiling platform". Paper presented in MicroRNAs Europe 2006 Meeting, 2006. Rocha, R.; Macedo-Ribeiro, S.; Gomes, A.C.; Santos, Manuel. "Structural and functional study of Candida albicans LeuRS, SerRS and tRNA(CAG)Ser". Paper presented in aaRS2006, International Conference on Amynoacyl-tRNA synthetases, 2006. J. Arrais; J.L. Oliveira; G. Campos; L. Carreto; Santos, Manuel. "Microarray data: from the hybridisation to the analysis". Paper presented in European Summer School in Biomedical Informatics, 2006. J. Arrais; L. Carreto; Santos, Manuel; J.L. Oliveira. "Collaborative work on microarrays using MAGE-ML". Paper presented in 9th International Meeting of the Microarray Gene Expression Data Society (MGED9), 2006. Gomes, A.C.; Miranda, I.; Thomas, B.; Akoulitchev, A.; Santos, Manuel. "The human pathpgen Candida albicans tolerates ambiguity of the CUG codon at very high level". Paper presented in 21th International tRNA Workshop (tRNA-2005), 2005. Rocha, R.; Costa, T.L.; Gomes, A.C.; Santos, Manuel. "Structural characterization of a genetic code change in the human pathogen Candida albicans". Paper presented in 21th International tRNA Workshop (tRNA-2005), 2005. Santos, Manuel; Beltrão, P.; Almeida, R.; Rocha, R.; Moura, Gabriela. "A genetic code change had a major impact on the evolution of the Candida albicans genome". Paper presented in 21th International tRNA Workshop (tRNA-2005), 2005. Moura, Gabriela; Miguel Pinheiro; Joel Arrais; Adelaide Valente; José Luís Oliveira; Santos, Manuel. "Comparative analysis of codon context biases in yeast genomes". Paper presented in ESF-EMBO Symposium on Comparative Genomics of Eukaryotic Microorganisms, 2005. João Paredes; Tatiana Lima-Costa; Raquel M. Silva; Michel Perrot; Hélian Boucherie; Santos, Manuel. "Characterization of the stress response induced by mRNA mistranslation in yeast". Paper presented in CSSi – 2nd International Congress on Stress Responses in Biology and Medicine, 2005. Raquel M. Silva; Tatiana Lima-Costa; João Paredes; Marian G. Koerkamp; Michel Perrot; Hélian Boucherie; Frank Holstege; Santos, Manuel. "mRNA mistranslation reprograms gene expression at the post-transcriptional level". Paper presented in CSSi – 2nd International Congress on Stress Responses in Biology and Medicine, 2005. Rocha, R.; Miranda, I.; Gomes, A.C.; Santos, Manuel. "CUG mistranslation in Candida albicans creates genome instability". Paper presented in EMBO Conference on Protein Synthesis and Translational Control, 2005. L. Carreto; M.C. Santos; J. Arrais; M. Rodrigues; L. Silva; J.L. Oliveira; Santos, Manuel. "Implementation of a national facility for DNA microarrays in Portugal". Paper presented in 8th International Meeting of the Microarray Gene Expression Data Society (MGED8), 2005. Isabel Miranda; Santos, Manuel. "Is CUG ambiguous decoding the basis for Candida albicans pathogenicity?". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Ana C. Gomes; Benjamin Thomas; A. Akoulitchev; Santos, Manuel. "The CUG codon is ambiguously decoded as leucine and serine in Candida albicans". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Raquel M. Silva; M. G. Koerkamp; Miechel Perrot; Hélian Boucherie; Frank Holstege; Santos, Manuel. "Transcriptome and proteome analysis of Saccharomyces cerevisiae cells that mistranslate the CUG codon". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Ana C. Gomes; Tatiana L. Costa; Patrícia Dolores Santo; Joana Pessoa; Santos, Manuel. "The molecular mechanism of CUG reassignment in Candida albicans". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Rita Rocha; Santos, Manuel. "Candida albicans mating is regulated by mistranslation of a reassigned codon". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Laura Carreto; Jacinto Pereira; José Luís Oliveira; Vera Afreixo; Adelaide Valente; Santos, Manuel. "Implementation of a DNA-microarray platform in the Functional Evolutionary Genomics Laboratory in Aveiro". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Jacinto Pereira; Laura Carreto; Santos, Manuel. "Design of a DNA chip for the diagnosis of pathogenic fungi". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. J. L. Oliveira; M. Pinheiro; Santos, Manuel; H. Rocha; M. L. Cardoso; L. Vilarinho. "On the Processing of MS/MS Data: an Application for Metabolic Diseases Screening". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. M. Pinheiro; V. Afreixo; Moura, Gabriela; A. Freitas; Santos, Manuel; J. L. Oliveira. "Bioinformation system for unveil general rules of codon context". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Patrícia Dolores Santo; Joana Sá Pessoa; Bibiana Ferreira; Santos, Manuel. "Elucidating the role of seryl- and leucyl-tRNA synthetases on the evolution of Candida albicans genetic code". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. L. Carreto; J. Pereira; J.L. Oliveira; A.S. Pereira; V. Afreixo; A. Valente; Santos, Manuel. "Implementation of a DNA-microarray platform for yeast expression, genome diversity and evolution and molecular diagnostics research". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. Raquel M. Silva; Marian G. Koerkamp; Michel Perrot; Hélian Boucherie; Frank Holstege; Santos, Manuel. "Molecular characterization of Saccharomyces cerevisiae cells expressing genetic code ambiguity". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. Isabel Miranda; Rita Rocha; Tatiana Lima-Costa; Santos, Manuel. "A major role for CUG ambiguity in Candida biology and evolution". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. Ana Catarina Gomes; Benjamin Thomas; Alexandre Akoulichev; Santos, Manuel. "Decoding ambiguity in the CUG codon in Candida albicans". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. Rita Rocha; Isabel Miranda; Tatiana Costa; Santos, Manuel. "Genome duplication and destabilization induced by mRNA decoding ambiguity in both S. cerevisiae and C. albicans". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. Moura, Gabriela; Miguel Pinheiro; Vera Afreixo; Adelaide Valente; José Luís Oliveira; Santos, Manuel. "Genome scale codon context analysis for Saccharomyces cerevisiae and Candida albicans". Paper presented in XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden, 2004. Santos, Manuel; R.M. Rocha; Moura, Gabriela; R. M. Silva. "A novel and critical role for a genetic code change in the evolution of the genus Candida". Paper presented in ASM Conference: Candida and Candidiasis (7th), 2004. Isabel Miranda; R. Rocha; Santos, Manuel. "A genetic code switch is a morphogenesis and matting trigger in Candida albicans". Paper presented in ASM Conference: Candida and Candidiasis (7th), 2004. Moura, Gabriela; M. Pinheiro; V. Afreixo; A. Valente; J. L. Oliveira; Santos, Manuel. "Comparative codon context analysis at a genomic scale defines new mRNA decoding rules". Paper presented in Translational Control Meeting, 2004. Santos, Manuel; Rocha, R.; Miranda, I.. "Mistranslation of a reassigned codon triggers morphogenesis and mating in Candida albicans". Paper presented in Translational Control Meeting, 2004. Silva, R.M.; Koerkamp, M.G.; Perrot, M.; Boucheria, H.; Holstege, F.; Santos, Manuel. "CUG mistranslation in Saccharomyces cerevisiae". Paper presented in Translational Control Meeting, 2004. M. Pinheiro; V. Afreixo; Moura, Gabriela; G. Dias; A.S. Pereira; A. Valente; Santos, Manuel; J. L. Oliveira. "Bioinformation system and statistical methodologies for gene primary structure analysis". Paper presented in EuroMISE 2004, 2004. Ana C. Gomes; Patrícia Dolores Santo; Santos, Manuel. "The evolution of the Candida albicans genetic code". 2003. Silva, R.; Gomes, A.C.; Santos, J.S.; Perrot, M.; Boucherie, H.; Santos, Manuel. "On the engineering of a genetic code change in yeast". Paper presented in XXIst International Conference on the Yeast Genetics and Molecular Biology, 2003. Santos, Manuel; Beltrão, P.; Almeida, R.; Massey, S.; Garey, J.; Moura, Gabriela. "Comparative evolutionary genomics of CUG reassignment in Candida species". 2003. Moura, Gabriela; Steve Massey; James R. Garey; Pedro Beltrão; Ricardo Almeida; Mick F. Tuite; Santos, Manuel. "Comparative genomics unravels the evolutionary pathway of a genetic code change in Candida spp.". Paper presented in ESF Programme in Functional Genomics: 1st European Conference (ESFFG'2003), 2003. José L. Oliveira; Miguel Pinheiro; Gaspar Dias; Moura, Gabriela; Vera Afreixo; Adelaide Valente; António S. Pereira; Santos, Manuel. "New software tools for comparative genomics". Paper presented in ESF Programme in Functional Genomics: 1st European Conference (ESFFG'2003), 2003. José L. Oliveira; Gaspar Dias; Raquel Silva; Santos, Manuel. "An open environment for management of proteomics data and projects". Paper presented in ESF Programme in Functional Genomics: 1st European Conference (ESFFG'2003), 2003. A. Furtado; J.L. Oliveira; A.S. Pereira; V. Maojo; F. Martin-Sanchez; A. Babic; Santos, Manuel. "Integration of genetic and clinical information sources for health applications". Paper presented in ESF Programme in Functional Genomics: 1st European Conference (ESFFG'2003), 2003. V. Afreixo; P.J.S.G. Ferreira; O.N.M. Pereira; Santos, Manuel; A. Valente. "Efficient methods for revealing structure in symbolic data". Paper presented in ESF Programme in Functional Genomics: 1st European Conference (ESFFG'2003), 2003. Miranda, I.M.; Santos, M.C.; Silva, R.; Santos, Manuel. "Genetic code ambiguity is a morphogenesis trigger in Candida albicans". Paper presented in Micro’2003, Congresso Nacional de Microbiologia, 2003. Gomes, A.C.; Santo, P.D.; Santos, Manuel; Ana C. Gomes; Patrícia Dolores Santo. "The evolution of the Candida albicans genetic code". Paper presented in Micro’2003, Congresso Nacional de Microbiologia, 2003. Empadinhas, N.; Albuquerque, L.; Costa, J.; Zinder, S.H.; Santos, Manuel; Santos, H.; da Costa, M.S.. "Development of an heterologous system for production of mannosylglycerate in Saccharomyces cerevisiae using a mesophilic bifunctional mannosylglycerate synthase gene from Dehalococcoides ethenogenes". Paper presented in Micro’2003, Congresso Nacional de Microbiologia, 2003. Moura, Gabriela; Steven, M.; James, G.; Pedro, B.; Ricardo, A.; Mick, F. T.; Santos, Manuel. "Decoding and evolution of the CUG codon in Candida spp.". Paper presented in XIII Congresso Nacional de Bioquímica, 2002. Ana C. Gomes; Isabel, M.; Teresa, N.; Patrícia, D.S.; Santos, M.; Santos, Manuel. "The evolutionary pathway of CUG reassignment in Candida albicans". Paper presented in XIII Congresso Nacional de Bioquímica, 2002. Raquel M. Silva; Jorge M. Santos; Michel Perrot; Helian Boucherie; Santos, Manuel. "A functional genomics approach to the evolution of alternative genetic codes". Paper presented in XIII Congresso Nacional de Bioquímica, 2002. Jorge M. Santos; Raquel M. Silva; Santos, Manuel. "On the evolution of an alternative genetic code in Candida spp.". Paper presented in Molecular Evolution: Evolution, Genomics and Bioinformatics, 2002. Moura, Gabriela; I. Miranda; C. Gomes; Santos, Manuel; Miranda, I.; Gomes, A.C.. "Non-standard translation and genetic code ambiguity in C. albicans". Paper presented in 27th Meeting of the FEBS, 2001. J.M. Santos; R.M. Silva; J.O. Branco; Santos, Manuel. "The global impact of ambiguous mRNA decoding on gene expression". 2001. Luís Reis; Paulo Almeida; Adelaide V. Freitas; Santos, Manuel. "New bioinformatics tools for genome analysis". Paper presented in XII Congresso Nacional de Bioquímica, 2000. Jorge Miguel Santos; Raquel Silva; Santos, Manuel. "Genetic code ambiguity as a novel mechanism for generating more competitive phenotypes". Paper presented in XII Congresso Nacional de Bioquímica, 2000. Moura, Gabriela; Isabel Miranda; Santos, Manuel. "Molecular characterization of non-standard translation in Candida albicans". Paper presented in XII Congresso Nacional de Bioquímica, 2000. Marta Tacão; Santos, Manuel. "BIOREDE: um local virtual para divulgação e apoio ao ensino da biologia molecular e da bioquímica". Paper presented in XII Congresso Nacional de Bioquímica, 2000. Justin M. O´Sullivan; Victoria M. Perreau; Santos, Manuel; Gerard Keith; Anna Przykorska; Mick F. Tuite. "The role of tRNA structure and identity in the evolution of codon reassignment". Paper presented in 18th tRNA workshop “tRNA 2000”, 2000. Santos, Manuel; Caroline Cheesman; Mick F. Tuite. "Re-programming gene expression by genetic code ambiguity in Saccharomyces cerevisiae". Paper presented in 18th tRNA workshop “tRNA 2000”, 2000. Santos, Manuel; Cheesman, C.; Tuite, M.F.. "The evolution of a genetic code change in Candida albicans: a novel mechanism for adaptation to new ecological niches?". Paper presented in 98th General Meeting of the American Society for Microbiology, 1998. Cheesman, C.; Chukeatirote, E.; Massey, S.; Santos, Manuel; Mick F. Tuite. "The evolution of codon reassignment in Candida species". Paper presented in Translation-UK 98, 1998. Ian Stansfield; Jones, K.M.; Pitts, S.; Ferreira, P.; Belfield, G.; Barron, C.; Santos, Manuel; Mick F. Tuite. "Assaying for increased translational errors in Saccharomyces cerevisiae". Paper presented in Translation-UK 98, 1998. Santos, Manuel; Perreau, V.M.; Tuite, M.F.. "tRNA structural change is a key element in the reassignment of the CUG codon from leucine to serine in Candida albicans". Paper presented in 17th International tRNA workshop, 1997. Santos, Manuel; Mick F. Tuite. "Expression of a novel Candida albicans seryl-tRNACAG in Saccharomyces cerevisiae induces the stress response: implications for the evolution of Candida pathogenesis". Paper presented in Microbial response to stress, 1997. Perreau, V.M.; Santos, Manuel; Tuite, M.F.. "Genomic organisation of the seryl-tRNACAG gene in Candida albicans". Paper presented in 16th International tRNA Workshop, 1995. Santos, Manuel; Perreau, V.M.; Tuite, M.F.. "The nature and evolution of serine-CUG decoding in Candida albicans". Paper presented in 16th International tRNA Workshop, 1995. Santos, Manuel; Perreau, V.; Keith, G.; Tuite, M.F.. "Decoding of the CUN codon family in Candida albicans does not conform to the universal genetic code". Paper presented in Translational Control Meeting, 1994. Santos, Manuel; Victoria Perreau; Mick F. Tuite. "Translational recoding of the CUG codon in Candida albicans". Paper presented in Translation U.K. 1994, 1994. Santos, Manuel; Victoria Perreau; Mick F. Tuite. "Translational recoding of the CUG codon in Candida albicans". 1994. Colthurst, D.R.; Santos, Manuel; Murphy, T.J.; Bauer, M.; Keith, G.; Tuite, M.F.. "Novel aspects of protein synthesis in Candida species". 1992. Tuite, M.F.; Colthurst, D.R.; Keith, G.; Santos, Manuel. "Non-standard translation events in Candida albicans". Paper presented in NATO Workshop: Protein synthesis and targeting in Yeast, 1992. Santos, Manuel; Keith. G.; Tuite, M.F.. "Non-standard translational events in Candida albicans mediated by an unusual leucine-tRNA". Paper presented in The Young Biochemists' Meeting (The Biochemical Society), 1992. Santos, Manuel; Keith, G.; Tuite, M.F.. "A C. albicans leucine tRNACAG that induces a non-standard translational event, in vitro". Paper presented in The Translational Apparatus, 1992. Santos, Manuel; Colthurst, D.; Bauer, M.; Keith, G.; Tuite, M.F.. "Recent findings in C.albicans protein synthesis and their potential as new drug targets". Paper presented in Biotec-92: IV Congreso National and I Hispano-Luso de Biotecnología, 1992. Colthurst, D.R.; Santos, Manuel; Murphy, T.J.; Bauer, M.; Keith, G.; Tuite, M.F.. "Novel aspects of protein synthesis in Candida species". Paper presented in Fungal Dimorphism: 4th Symposium on Topics in Mycology, 1992. Santos, Manuel; Colthurst, D.R.; Keith, G.; Dirheimer, G.; Tuite, M.F.. "Characterization of a novel suppressor tRNA from the human pathogen Candida albicans". Paper presented in 14th International tRNA Workshop, 1991. Tuite, M.F.; Colthurst, D.R.; Santos, Manuel. "The identification and possible exploitation of novel antifungal targets". Paper presented in Antimicrobial agents, GESA XXI, 1991. Santos, Manuel; Seleiro, E.; Costa, M.S.. "Physiology and taxonomy of several Thermus strains isolated in Portugal". Paper presented in Primeiro encontro da Sociedade Portuguesa de Biotecnologia, 1988.
Journal article	Rui M Ferreira; Joana Figueiredo; Ines Pinto-Ribeiro; Irene Gullo; Dionyssios N Sgouras; Laura Carreto; Patricia Castro; et al. "Activation of Laminin ¿2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects". The Journal of Infectious Diseases 226 (2022): 2226-2237. https://academic.oup.com/jid/article/226/12/2226/6731086. 10.1093/infdis/jiac397 Santos, Mafalda; Fidalgo, Ana; Varanda, Ana Sofia; Soares, Ana Raquel; Almeida, Gabriela M.; Martins, Diana; Mendes, Nuno; Oliveira, Carla; Santos, Manuel A. S.. "Upregulation of tRNA-Ser-AGA-2-1 Promotes Malignant Behavior in Normal Bronchial Cells". Frontiers in Molecular Biosciences 9 (2022): http://dx.doi.org/10.3389/fmolb.2022.809985. 10.3389/fmolb.2022.809985 Francisco, Stephany; Martinho, Vera; Ferreira, Margarida; Reis, Andreia; Moura, Gabriela; Soares, Ana Raquel; Santos, Manuel A. S.. "The Role of MicroRNAs in Proteostasis Decline and Protein Aggregation during Brain and Skeletal Muscle Aging". International Journal of Molecular Sciences 23 6 (2022): 3232. http://dx.doi.org/10.3390/ijms23063232. 10.3390/ijms23063232 Marçalo, Rui; Neto, Sonya; Pinheiro, Miguel; Rodrigues, Ana J.; Sousa, Nuno; Santos, Manuel A. S.; Simão, Paula; et al. "Evaluation of the genetic risk for COVID-19 outcomes in COPD and differences among worldwide populations". PLOS ONE 17 2 (2022): e0264009. http://dx.doi.org/10.1371/journal.pone.0264009. 10.1371/journal.pone.0264009 Santiago, Joana; Silva, Joana V; Howl, John; Santos, Manuel A S; Fardilha, Margarida. "All you need to know about sperm RNAs". Human Reproduction Update 28 1 (2021): 67-91. http://dx.doi.org/10.1093/humupd/dmab034. 10.1093/humupd/dmab034 Ferreira, Margarida; Francisco, Stephany; Soares, Ana R.; Nobre, Ana; Pinheiro, Miguel; Reis, Andreia; Neto, Sonya; et al. "Integration of segmented regression analysis with weighted gene correlation network analysis identifies genes whose expression is remodeled throughout physiological aging in mouse tissues". Aging 13 14 (2021): 18150-18190. http://dx.doi.org/10.18632/aging.203379. 10.18632/aging.203379 Direito, Inês; Monteiro, Liliana; Melo, Tânia; Figueira, Daniela; Lobo, João; Enes, Vera; Moura, Gabriela; et al. "Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance". Cancers 13 13 (2021): 3195. http://dx.doi.org/10.3390/cancers13133195. 10.3390/cancers13133195 Bezerra, Ana Rita; Oliveira, Carla; Correia, Inês; Guimarães, Ana Rita; Sousa, Gonçalo; Carvalho, Maria João; Moura, Gabriela; Santos, Manuel A S. "The role of non-standard translation in Candida albicans pathogenesis". FEMS Yeast Research 21 4 (2021): http://dx.doi.org/10.1093/femsyr/foab032. 10.1093/femsyr/foab032 Guimarães, Ana Rita; Correia, Inês; Sousa, Inês; Oliveira, Carla; Moura, Gabriela; Bezerra, Ana Rita; Santos, Manuel A. S.. "tRNAs as a Driving Force of Genome Evolution in Yeast". Frontiers in Microbiology 12 (2021): http://dx.doi.org/10.3389/fmicb.2021.634004. 10.3389/fmicb.2021.634004 Santiago, Joana; Silva, Joana V.; Santos, Manuel A. S.; Fardilha, Margarida. "Fighting Bisphenol A-Induced Male Infertility: The Power of Antioxidants". Antioxidants 10 2 (2021): 289. http://dx.doi.org/10.3390/antiox10020289. 10.3390/antiox10020289 Vitorino, Rui; Guedes, Sofia; Amado, Francisco; Santos, Manuel; Akimitsu, Nobuyoshi. "The role of micropeptides in biology". Cellular and Molecular Life Sciences 78 7 (2021): 3285-3298. http://dx.doi.org/10.1007/s00018-020-03740-3. 10.1007/s00018-020-03740-3 Castanho, T.C.; Santos, N.C.; Meleiro-Neves, C.; Neto, S.; Moura, G.R.; Santos, M.A.; Cruz, A.R.; et al. "Association of positive and negative life events with cognitive performance and psychological status in late life: A cross-sectional study in Northern Portugal". Aging Brain 1 (2021): 100020. http://dx.doi.org/10.1016/j.nbas.2021.100020. 10.1016/j.nbas.2021.100020 Tavares, Joana F; Davis, Nick K.; Poim, Ana; Reis, Andreia; Kellner, Stefanie; Sousa, Inês; Soares, Ana R.; et al. "tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast". RNA Biology 18 4 (2020): 563-575. http://dx.doi.org/10.1080/15476286.2020.1819671. 10.1080/15476286.2020.1819671 Francisco, Stephany; Ferreira, Margarida; Moura, Gabriela; Soares, Ana Raquel; Santos, Manuel A.S.. "Does proteostasis get lost in translation? Implications for protein aggregation across the lifespan". Ageing Research Reviews 62 (2020): 101119. http://dx.doi.org/10.1016/j.arr.2020.101119. 10.1016/j.arr.2020.101119 Nunes, Alexandre; Ribeiro, Diana Roberta; Marques, Mariana; Santos, Manuel A.S.; Ribeiro, Daniela; Soares, Ana Raquel. "Emerging Roles of tRNAs in RNA Virus Infections". Trends in Biochemical Sciences 45 9 (2020): 794-805. http://dx.doi.org/10.1016/j.tibs.2020.05.007. 10.1016/j.tibs.2020.05.007 Vitorino, Rui; Guedes, Sofia; Trindade, Fabio; Correia, Inês; Moura, Gabriela; Carvalho, Paulo; Santos, Manuel A. S.; Amado, Francisco. "De novo sequencing of proteins by mass spectrometry". Expert Review of Proteomics 17 7-8 (2020): 595-607. http://dx.doi.org/10.1080/14789450.2020.1831387. 10.1080/14789450.2020.1831387 Varanda, Ana Sofia; Santos, Mafalda; Soares, Ana Raquel; Vitorino, Rui; Oliveira, Patrícia; Oliveira, Carla; Santos, Manuel. "Human cells adapt to translational errors by modulating protein synthesis rate and protein turnover". RNA Biology 17 1 (2020): 135-149. http://dx.doi.org/10.1080/15476286.2019.1670039. 10.1080/15476286.2019.1670039 Nogueira-Ferreira, Rita; Ferreira, Rita; Padrão, Ana Isabel; Oliveira, Paula; Santos, Manuel; Kavazis, Andreas N.; Vitorino, Rui; Moreira-Gonçalves, Daniel. "One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats". Journal of Physiology and Biochemistry 75 4 (2019): 561-572. http://dx.doi.org/10.1007/s13105-019-00705-4. 10.1007/s13105-019-00705-4 Varanda, Ana Sofia; Santos, Mafalda; Soares, Ana R.; Vitorino, Rui; Oliveira, Patrícia; Oliveira, Carla; Santos, Manuel A. S.. "Human cells adapt to translational errors by modulating protein synthesis rate and protein turnover". RNA Biology 17 1 (2019): 135-149. http://dx.doi.org/10.1080/15476286.2019.1670039. 10.1080/15476286.2019.1670039 Varanda, Ana Sofia; Santos, Mafalda; Soares, Ana R.; Vitorino, Rui; Oliveira, Patrícia; Oliveira, Carla; Santos, Manuel A. S.. "Human cells adapt to translational errors by modulating protein synthesis rate and protein turnover". RNA Biology 17 1 (2019): 135-149. http://dx.doi.org/10.1080/15476286.2019.1670039. 10.1080/15476286.2019.1670039 Santos, Mafalda; Fidalgo, Ana; Varanda, A. Sofia; Oliveira, Carla; Santos, Manuel. "tRNA Deregulation and Its Consequences in Cancer". Trends in Molecular Medicine 25 10 (2019): 853-865. http://dx.doi.org/10.1016/j.molmed.2019.05.011. Published • 10.1016/j.molmed.2019.05.011 Silva, Mariline M.; Rodrigues, Beatriz; Fernandes, Joana; Santos, Sandra D.; Carreto, Laura; Santos, Manuel; Pinheiro, Paulo; Carvalho, Ana Luísa. "MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons". Proceedings of the National Academy of Sciences 116 12 (2019): 5727-5736. http://dx.doi.org/10.1073/pnas.1900338116. Published • 10.1073/pnas.1900338116 Cela, Marta; Paulus, Caroline; Santos, Manuel; Moura, Gabriela; Frugier, Magali; Rudinger-Thirion, Joëlle. "Plasmodium apicoplast tyrosyl-tRNA synthetase recognizes an unusual, simplified identity set in cognate tRNATyr". PLOS ONE 13 12 (2018): http://dx.doi.org/10.1371/journal.pone.0209805. Published • 10.1371/journal.pone.0209805 Perego, Jessica; Mendes, A; Bourbon, Clarisse; Camosseto, Voahirana; Combes, Alexis; Liu, Hong; Manh, Thien-Phong Vu; et al. "Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2a dephosphorylation by the GADD34/PP1c complex". Science Signaling 11 514 (2018): http://dx.doi.org/10.1126/scisignal.aam8104. Published • 10.1126/scisignal.aam8104 Santos, M.; Pereira, P.M.; Varanda, A.S.; Carvalho, J.; Azevedo, M.; Mateus, D.D.; Mendes, N.; et al. "Codon misreading tRNAs promote tumor growth in mice". RNA Biology 15 6 (2018): 773-786. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048065304&partnerID=MN8TOARS. 10.1080/15476286.2018.1454244 Pereira, M.; Tomé, D.; Domingues, A.S.; Varanda, A.S.; Paulo, C.; Santos, M.A.S.; Soares, A.R.. "A Fluorescence-Based Sensor Assay that Monitors General Protein Aggregation in Human Cells". Biotechnology Journal 13 4 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85043346932&partnerID=MN8TOARS. 10.1002/biot.201700676 Pereira, M.; Francisco, S.; Varanda, A.S.; Santos, M.; Santos, M.A.S.; Soares, A.R.. "Impact of tRNA modifications and tRNA-modifying enzymes on proteostasis and human disease". International Journal of Molecular Sciences 19 12 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85057211964&partnerID=MN8TOARS. 10.3390/ijms19123738 Tavares, Joana; Santos, Filipe Assis; Santos, Manuel. "Proteomics Analysis for Amino Acid Misincorporation Detection: Mini Review". Journal of Proteomics & Bioinformatics 11 2 (2018): 45-50. http://dx.doi.org/10.4172/jpb.1000464. Published • 10.4172/jpb.1000464 Araújo, A.R.D.; Melo, T.; Maciel, E.A.; Pereira, C.; Morais, C.M.; Santinha, D.R.; Tavares, J.F.; et al. "Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast". PLoS ONE 13 8 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85052640327&partnerID=MN8TOARS. 10.1371/journal.pone.0202402 Magalhães, S.; Graça, Ana; Tavares, Joana; Santos, Manuel; Delgadillo, Ivonne; Nunes, Alexandra. "Saccharomyces cerevisiae as a Model to Confirm the Ability of FTIR to Evaluate the Presence of Protein Aggregates". Spectral Analysis Review 06 01 (2017): 1-11. http://dx.doi.org/10.4236/sar.2018.61001. Published • 10.4236/sar.2018.61001 Bódi, Zoltán; Farkas, Zoltán; Nevozhay, Dmitry; Kalapis, Dorottya; Lázár, Viktória; Csörgo, Bálint; Nyerges, Ákos; et al. "Phenotypic heterogeneity promotes adaptive evolution". PLOS Biology 15 6 (2017): http://dx.doi.org/10.1371/journal.pbio.1002607. Published • 10.1371/journal.pbio.1002607 Soares, Ana Raquel; Santos, Manuel. "Discovery and function of transfer RNA-derived fragments and their role in disease". Wiley Interdisciplinary Reviews: RNA 8 5 (2017): http://dx.doi.org/10.1002/wrna.1423. Published • 10.1002/wrna.1423 Dalet, Alexandre; Argüello, Rafael J; Combes, Alexis; Spinelli, Lionel; Jaeger, Sebastien; Fallet, Mathieu; Vu Manh, Thien-Phong; et al. "Protein synthesis inhibition and GADD34 control IFN-ß heterogeneous expression in response to dsRNA". The EMBO Journal 36 6 (2017): 761-782. http://dx.doi.org/10.15252/embj.201695000. Published • 10.15252/embj.201695000 Leal, Graciano; Comprido, Diogo; de Luca, Pasqualino; Morais, Eduardo; Rodrigues, Luís; Mele, Miranda; Santos, Ana R.; et al. "The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons". eneuro 4 6 (2017): http://dx.doi.org/10.1523/eneuro.0268-17.2017. Published • 10.1523/eneuro.0268-17.2017 Weil, T.; Santamaría, R.; Lee, W.; Rung, J.; Tocci, N.; Abbey, D.; Bezerra, A.R.; et al. "Adaptive mistranslation accelerates the evolution of fluconazole resistance and induces major genomic and gene expression alterations in Candida albicans". mSphere 2 4 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040978047&partnerID=MN8TOARS. Published • 10.1128/mSphere.00167-17 Ferreira, Catarina; Soares, Ana Raquel; Lamosa, Pedro; Santos, Manuel; da Costa, Milton S.. "Comparison of the compatible solute pool of two slightly halophilic planctomycetes species, Gimesia maris and Rubinisphaera brasiliensis". Extremophiles 20 6 (2016): 811-820. http://dx.doi.org/10.1007/s00792-016-0868-0. Published • 10.1007/s00792-016-0868-0 Simões, João; Bezerra, Ana R.; Moura, Gabriela; Araújo, Hugo; Gut, Ivo; Bayes, Mónica; Santos, Manuel. "The Fungus Candida albicans Tolerates Ambiguity at Multiple Codons". Frontiers in Microbiology 7 (2016): http://dx.doi.org/10.3389/fmicb.2016.00401. Published • 10.3389/fmicb.2016.00401 Rizzetto, Lisa; Ifrim, Daniela C.; Moretti, Silvia; Tocci, Noemi; Cheng, Shih-Chin; Quintin, Jessica; Renga, Giorgia; et al. "Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host withSaccharomyces cerevisiae". Journal of Biological Chemistry 291 15 (2016): 7961-7972. http://dx.doi.org/10.1074/jbc.m115.699645. Published • 10.1074/jbc.m115.699645 Costa, Angela M.; Ferreira, Rui M.; Pinto-Ribeiro, Ines; Sougleri, Ioanna S.; Oliveira, Maria J.; Carreto, Laura; Santos, Manuel; et al. "Helicobacter pylori Activates Matrix Metalloproteinase 10 in Gastric Epithelial Cells via EGFR and ERK-mediated Pathways". Journal of Infectious Diseases 213 11 (2016): 1767-1776. http://dx.doi.org/10.1093/infdis/jiw031. Published • 10.1093/infdis/jiw031 Gaspar, P.; Moura, G.; Santos, M.A.S.; Oliveira, J.L.. "Erratum : mRNA secondary structure optimization using a correlated stem-loop prediction (Nucleic Acids Research (2013) 41:6 (e73) DOI: 10.1093/nar/gks1473)". Nucleic Acids Research 44 11 (2016): 5490-5490. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976435942&partnerID=MN8TOARS. 10.1093/nar/gkw127 Gaspar, P.; Luís Oliveira, J.; Frommlet, J.; Santos, M.A.S.; Moura, G.. "Erratum: EuGene: Maximizing synthetic gene design for heterologous expression (Bioinformatics (2012) 28: 20 (2683-2684))". Bioinformatics 32 7 (2016): 1120-1120. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964432672&partnerID=MN8TOARS. 10.1093/bioinformatics/btw063 Soares, Ana Raquel; Fernandes, Noémia; Reverendo, Marisa; Araújo, Hugo Rafael; Oliveira, José Luís; Moura, Gabriela; Santos, Manuel. "Conserved and highly expressed tRNA derived fragments in zebrafish". BMC Molecular Biology 16 1 (2015): http://dx.doi.org/10.1186/s12867-015-0050-8. Published • 10.1186/s12867-015-0050-8 Bezerra, Ana; Guimarães, Ana; Santos, Manuel. "Non-Standard Genetic Codes Define New Concepts for Protein Engineering". Life 5 4 (2015): 1610-1628. http://dx.doi.org/10.3390/life5041610. Published • 10.3390/life5041610 Kalapis, Dorottya; Bezerra, Ana R.; Farkas, Zoltán; Horvath, Peter; Bódi, Zoltán; Daraba, Andreea; Szamecz, Béla; et al. "Evolution of Robustness to Protein Mistranslation by Accelerated Protein Turnover". PLOS Biology 13 11 (2015): e1002291. http://dx.doi.org/10.1371/journal.pbio.1002291. Published • 10.1371/journal.pbio.1002291 Terawaki, Seigo; Camosseto, Voahirana; Prete, Francesca; Wenger, Till; Papadopoulos, Alexia; Rondeau, Christiane; Combes, Alexis; et al. "RUN and FYVE domain–containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4". The Journal of Cell Biology 210 7 (2015): 1133-1152. http://dx.doi.org/10.1083/jcb.201501059. Published • 10.1083/jcb.201501059 Franco-Duarte, Ricardo; Bigey, Frédéric; Carreto, Laura; Mendes, Inês; Dequin, Sylvie; Santos, Manuel; Pais, Célia; Schuller, Dorit. "Intrastrain genomic and phenotypic variability of the commercialSaccharomyces cerevisiaestrain Zymaflore VL1 reveals microevolutionary adaptation to vineyard environments". FEMS Yeast Research 15 6 (2015): fov063. http://dx.doi.org/10.1093/femsyr/fov063. Published • 10.1093/femsyr/fov063 Ragionieri, Lapo; Vitorino, Rui; Frommlet, Joerg; Oliveira, José L.; Gaspar, Paulo; Ribas de Pouplana, Lluís; Santos, Manuel; Moura, Gabriela. "Improving the accuracy of recombinant protein production through integration of bioinformatics, statistical and mass spectrometry methodologies". The FEBS Journal 282 4 (2015): 769-787. http://dx.doi.org/10.1111/febs.13181. Published • 10.1111/febs.13181 Moura, G.R.; Pinheiro, M.; Freitas, A.; Oliveira, J.L.; Frommlet, J.C.; Carreto, L.; Soares, A.R.; Bezerra, A.R.; Santos, M.A.S.. "Erratum: Species-Specific Codon Context Rules Unveil Non-Neutrality Effects of Synonymous Mutations (PLoS ONE (2011) 6:10 (e26817))". PLoS ONE 10 12 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84956899012&partnerID=MN8TOARS. 10.1371/journal.pone.0145593 Calejo, A. I.; Jorga evski, J.; Rituper, B.; Gu ek, A.; Pereira, P. M.; Santos, Manuel; Potokar, M.; et al. "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels and cAMP-Dependent Modulation of Exocytosis in Cultured Rat Lactotrophs". Journal of Neuroscience 34 47 (2014): 15638-15647. http://dx.doi.org/10.1523/jneurosci.5290-13.2014. Published • 10.1523/jneurosci.5290-13.2014 Ribas de Pouplana, Liuís; Santos, Manuel; Zhu, Jun-Hao; Farabaugh, Philip J.; Javid, Babak. "Protein mistranslation: friend or foe?". Trends in Biochemical Sciences 39 8 (2014): 355-362. http://dx.doi.org/10.1016/j.tibs.2014.06.002. Published • 10.1016/j.tibs.2014.06.002 Vieira, M.; Fernandes, J.; Carreto, L.; Anuncibay-Soto, B.; Santos, Manuel; Han, J.; Fernández-López, A.; et al. "Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3". Neurobiology of Disease 68 (2014): 26-36. http://dx.doi.org/10.1016/j.nbd.2014.04.002. Published • 10.1016/j.nbd.2014.04.002 Pimentel, Catarina; Caetano, Soraia M.; Menezes, Regina; Figueira, Inês; Santos, Claudia N.; Ferreira, Ricardo B.; Santos, Manuel; Rodrigues-Pousada, Claudina. "Yap1 mediates tolerance to cobalt toxicity in the yeast Saccharomyces cerevisiae". Biochimica et Biophysica Acta (BBA) - General Subjects 1840 6 (2014): 1977-1986. http://dx.doi.org/10.1016/j.bbagen.2014.01.032. Published • 10.1016/j.bbagen.2014.01.032 Bernardes, Nuno; Ribeiro, Ana Sofia; Abreu, Sofia; Vieira, André F.; Carreto, Laura; Santos, Manuel; Seruca, Raquel; Paredes, Joana; Fialho, Arsenio M.. "High-throughput molecular profiling of a P-cadherin overexpressing breast cancer model reveals new targets for the anti-cancer bacterial protein azurin". The International Journal of Biochemistry & Cell Biology 50 (2014): 1-9. http://dx.doi.org/10.1016/j.biocel.2014.01.023. Published • 10.1016/j.biocel.2014.01.023 Bordeira-Carriço, Renata; Ferreira, Daniel; Mateus, Denisa D; Pinheiro, Hugo; Pêgo, Ana Paula; Santos, Manuel; Oliveira, Carla. "Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA". European Journal of Human Genetics 22 9 (2014): 1085-1092. http://dx.doi.org/10.1038/ejhg.2013.292. Published • 10.1038/ejhg.2013.292 Reverendo, M.; Soares, A.R.; Pereira, P.M.; Carreto, L.; Ferreira, V.; Gatti, E.; Pierre, P.; Moura, G.R.; Santos, M.A.. "TRNA mutations that affect decoding fidelity deregulate development and the proteostasis network in zebrafish". RNA Biology 11 9 (2014): 1199-1213. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921709623&partnerID=MN8TOARS. 10.4161/rna.32199 Fernandes, J.; Vieira, M.; Carreto, L.; Santos, M.A.S.; Duarte, C.B.; Carvalho, A.L.; Santos, A.E.. "In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons". PLoS ONE 9 6 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84903512303&partnerID=MN8TOARS. 10.1371/journal.pone.0099958 Calejo, Ana I.; Reverendo, Marisa; Silva, Virgília S.; Pereira, Patrícia M.; Santos, Manuel; Zorec, Robert; Gonçalves, Paula P.. "Differences in the expression pattern of HCN isoforms among mammalian tissues: sources and implications". Molecular Biology Reports 41 1 (2013): 297-307. http://dx.doi.org/10.1007/s11033-013-2862-2. Published • 10.1007/s11033-013-2862-2 Alam, M. Z.; Ragionieri, L.; Santos, Manuel; Iqbal, A.. "Heterologous Expression and Purification of ? Galactosidase Protein Using Affinity Chromatography". Journal of Scientific Research 5 3 (2013): 499-513. http://dx.doi.org/10.3329/jsr.v5i3.13820. Published • 10.3329/jsr.v5i3.13820 Hoen, Rob; Novoa, Eva Maria; López, Alba; Camacho, Noelia; Cubells, Laia; Vieira, Pedro; Santos, Manuel; et al. "Selective Inhibition of an Apicoplastic Aminoacyl-tRNA Synthetase from Plasmodium falciparum". ChemBioChem 14 4 (2013): 499-509. http://dx.doi.org/10.1002/cbic.201200620. Published • 10.1002/cbic.201200620 Gaspar, Paulo; Moura, Gabriela; Santos, Manuel; Oliveira, José Luís. "mRNA secondary structure optimization using a correlated stem–loop prediction". Nucleic Acids Research 41 6 (2013): e73-e73. http://dx.doi.org/10.1093/nar/gks1473. Published • 10.1093/nar/gks1473 Miranda, I.; Silva-Dias, A.; Rocha, R.; Teixeira-Santos, R.; Coelho, C.; Gonçalves, T.; Santos, M.A.S.; et al. "Candida albicans CUG mistranslation is a mechanism to create cell surface variation". mBio 4 4 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84883429281&partnerID=MN8TOARS. Published • 10.1128/mBio.00285-13 Ribeiro, A.S.; Sousa, B.; Carreto, L.; Mendes, N.; Nobre, A.R.; Ricardo, S.; Albergaria, A.; et al. "P-cadherin functional role is dependent on E-cadherin cellular context: A proof of concept using the breast cancer model". Journal of Pathology 229 5 (2013): 705-718. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875054847&partnerID=MN8TOARS. 10.1002/path.4143 Quintela, T.; Gonçalves, I.; Carreto, L.C.; Santos, M.A.S.; Marcelino, H.; Patriarca, F.M.; Santos, C.R.A.. "Analysis of the Effects of Sex Hormone Background on the Rat Choroid Plexus Transcriptome by cDNA Microarrays". PLoS ONE 8 4 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84876025530&partnerID=MN8TOARS. 10.1371/journal.pone.0060199 Mateus, D.D.; Paredes, J.A.; Español, Y.; De Pouplana, L.R.; Moura, G.R.; Santos, M.A.S.. "Molecular reconstruction of a fungal genetic code alteration". RNA Biology 10 6 (2013): 961-973. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879488664&partnerID=MN8TOARS. 10.4161/rna.24683 Bezerra, A.R.; Simões, J.; Lee, W.; Rung, J.; Weil, T.; Gut, I.G.; Gut, M.; et al. "Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification". Proceedings of the National Academy of Sciences of the United States of America 110 27 (2013): 11079-11084. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879727622&partnerID=MN8TOARS. 10.1073/pnas.1302094110 Silva, A.; Sampaio-Marques, B.; Fernandes, Â.; Carreto, L.; Rodrigues, F.; Holcik, M.; Santos, M.A.S.; Ludovico, P.. "Involvement of Yeast HSP90 Isoforms in Response to Stress and Cell Death Induced by Acetic Acid". PLoS ONE 8 8 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84881561857&partnerID=MN8TOARS. 10.1371/journal.pone.0071294 Bordeira-Carriço, Renata; Pêgo, Ana Paula; Santos, Manuel; Oliveira, Carla. "Cancer syndromes and therapy by stop-codon readthrough". Trends in Molecular Medicine 18 11 (2012): 667-678. http://dx.doi.org/10.1016/j.molmed.2012.09.004. Published • 10.1016/j.molmed.2012.09.004 Gaspar, P.; Oliveira, J. L.; Frommlet, J.; Santos, Manuel; Moura, Gabriela. "EuGene: maximizing synthetic gene design for heterologous expression". Bioinformatics 28 20 (2012): 2683-2684. http://dx.doi.org/10.1093/bioinformatics/bts465. Published • 10.1093/bioinformatics/bts465 Soares, Ana Raquel; Pereira, Patrícia M.; Ferreira, Violeta; Reverendo, Marisa; Simões, João; Bezerra, Ana Rita; Moura, Gabriela; Santos, Manuel. "Ethanol Exposure Induces Upregulation of Specific MicroRNAs in Zebrafish Embryos". Toxicological Sciences 127 1 (2012): 18-28. http://dx.doi.org/10.1093/toxsci/kfs068. Published • 10.1093/toxsci/kfs068 Paredes, João A; Carreto, Laura; Simões, João; Bezerra, Ana R; Gomes, Ana C; Santamaria, Rodrigo; Kapushesky, Misha; Moura, Gabriela; Santos, Manuel. "Low level genome mistranslations deregulate the transcriptome and translatome and generate proteotoxic stress in yeast". BMC Biology 10 1 (2012): 55. http://dx.doi.org/10.1186/1741-7007-10-55. Published • 10.1186/1741-7007-10-55 Lousado, José Paulo; Oliveira, José Luis; Moura, Gabriela; Santos, Manuel; Lousado, J.P.; Oliveira, J.L.; Moura, G.; Santos, M.A.S.. "An integrative approach for codon repeats evolutionary analyses". International Journal of Data Mining and Bioinformatics 6 4 (2012): 369-381. http://dx.doi.org/10.1504/ijdmb.2012.049294. Published • 10.1504/ijdmb.2012.049294 Schuller, D.; Cardoso, F.; Sousa, S.; Gomes, P.; Gomes, A.C.; Santos, M.A.S.; Casal, M.. "Genetic diversity and population structure of saccharomyces cerevisiae strains isolated from different grape varieties and winemaking regions". PLoS ONE 7 2 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84857676912&partnerID=MN8TOARS. 10.1371/journal.pone.0032507 Soares, A.R.; Reverendo, M.; Pereira, P.M.; Nivelles, O.; Pendeville, H.; Bezerra, A.R.; Moura, G.R.; Struman, I.; Santos, M.A.S.. "Dre-miR-2188 targets Nrp2a and mediates proper intersegmental vessel development in zebrafish embryos". PLoS ONE 7 6 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84862690378&partnerID=MN8TOARS. 10.1371/journal.pone.0039417 Carvalho, J.; Van Grieken, N.C.; Pereira, P.M.; Sousa, S.; Tijssen, M.; Buffart, T.E.; Diosdado, B.; et al. "Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer". Journal of Pathology 228 1 (2012): 31-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864749110&partnerID=MN8TOARS. 10.1002/path.4032 Santamaría, Rodrigo; Rizzetto, Lisa; Bromley, Michael; Zelante, Teresa; Lee, Wanseon; Cavalieri, Duccio; Romani, Luigina; et al. "Systems biology of infectious diseases: a focus on fungal infections". Immunobiology 216 11 (2011): 1212-1227. http://dx.doi.org/10.1016/j.imbio.2011.08.004. Published • 10.1016/j.imbio.2011.08.004 Jackson, Katherine E.; Habib, Saman; Frugier, Magali; Hoen, Rob; Khan, Sameena; Pham, James S.; Pouplana, Lluís Ribas de; et al. "Protein translation in Plasmodium parasites". Trends in Parasitology 27 10 (2011): 467-476. http://dx.doi.org/10.1016/j.pt.2011.05.005. Published • 10.1016/j.pt.2011.05.005 Novais, Sara C.; Howcroft, Clara F.; Carreto, Laura; Pereira, Patrícia M.; Santos, Manuel; De Coen, Wim; Soares, Amadeu M. V. M.; Amorim, Mónica J. B.. "Differential gene expression analysis in Enchytraeus albidus exposed to natural and chemical stressors at different exposure periods". Ecotoxicology 21 1 (2011): 213-224. http://dx.doi.org/10.1007/s10646-011-0780-4. Published • 10.1007/s10646-011-0780-4 Santos, Manuel; Gomes, Ana C.; Santos, Maria C.; Carreto, Laura C.; Moura, Gabriela. "The genetic code of the fungal CTG clade". Comptes Rendus Biologies 334 8-9 (2011): 607-611. http://dx.doi.org/10.1016/j.crvi.2011.05.008. Published • 10.1016/j.crvi.2011.05.008 Franco-Duarte, Ricardo; Mendes, Inês; Gomes, Ana Catarina; Santos, Manuel; de Sousa, Bruno; Schuller, Dorit. "Genotyping of Saccharomyces cerevisiae strains by interdelta sequence typing using automated microfluidics". Electrophoresis 32 12 (2011): 1447-1455. http://dx.doi.org/10.1002/elps.201000640. Published • 10.1002/elps.201000640 Freitas, A.; Afreixo, V.; Pinheiro, M.; Oliveira, J. L.; Moura, Gabriela; Santos, Manuel. "Improving the performance of the iterative signature algorithm for the identification of relevant patterns". Statistical Analysis and Data Mining 4 1 (2011): 71-83. http://dx.doi.org/10.1002/sam.10104. Published • 10.1002/sam.10104 Rocha, R.; Barbosa Pereira, P.J.; Santos, M.A.S.; MacEdo-Ribeiro, S.; Rocha, Rita; Barbosa Pereira, Pedro José; Santos, Manuel; Macedo-Ribeiro, Sandra. "Purification, crystallization and preliminary X-ray diffraction analysis of the seryl-tRNA synthetase from Candida albicans". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 67 1 (2011): 153-156. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651065708&partnerID=MN8TOARS. Published • 10.1107/S1744309110048542 Carreto, L.; Eiriz, M.F.; Domingues, I.; Schuller, D.; Moura, G.R.; Santos, M.A.S.. "Expression variability of co-regulated genes differentiates Saccharomyces cerevisiae strains". BMC Genomics 12 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79954600765&partnerID=MN8TOARS. 10.1186/1471-2164-12-201 Rocha, R.; Pereira, P.J.B.; Santos, M.A.S.; Macedo-Ribeiro, S.. "Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen". Proceedings of the National Academy of Sciences of the United States of America 108 34 (2011): 14091-14096. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052182956&partnerID=MN8TOARS. 10.1073/pnas.1102835108 Ibba, M.; Santos, M.A.S.. "Transfer RNA". FEBS Letters 584 2 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-71549115416&partnerID=MN8TOARS. 10.1016/j.febslet.2009.11.080 Pereira, P.M.; Marques, J.P.; Soares, A.R.; Carreto, L.; Santos, M.A.S.. "Microrna expression variability in human cervical tissues". PLoS ONE 5 7 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77955615260&partnerID=MN8TOARS. 10.1371/journal.pone.0011780 Santos, M.A.S.; Orellana, O.; Ibba, M.. "Transfer RNA's latest port of call". RNA Biology 7 5 (2010): 517-520. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649374380&partnerID=MN8TOARS. 10.4161/rna.7.5.13213 Frugier, M.; Bour, T.; Ayach, M.; Santos, M.A.S.; Rudinger-Thirion, J.; Théobald-Dietrich, A.; Pizzi, E.. "Low Complexity Regions behave as tRNA sponges to help co-translational folding of plasmodial proteins". FEBS Letters 584 2 (2010): 448-454. http://www.scopus.com/inward/record.url?eid=2-s2.0-71549152207&partnerID=MN8TOARS. 10.1016/j.febslet.2009.11.004 Moura, G.R.; Paredes, J.A.; Santos, M.A.S.. "Development of the genetic code: Insights from a fungal codon reassignment". FEBS Letters 584 2 (2010): 334-341. http://www.scopus.com/inward/record.url?eid=2-s2.0-71549136142&partnerID=MN8TOARS. 10.1016/j.febslet.2009.11.066 Moura, Gabriela; Carreto, Laura C; Santos, Manuel. "Genetic code ambiguity: an unexpected source of proteome innovation and phenotypic diversity". Current Opinion in Microbiology 12 6 (2009): 631-637. http://dx.doi.org/10.1016/j.mib.2009.09.004. Published • 10.1016/j.mib.2009.09.004 Butler, Geraldine; Rasmussen, Matthew D.; Lin, Michael F.; Santos, Manuel; Sakthikumar, Sharadha; Munro, Carol A.; Rheinbay, Esther; et al. "Evolution of pathogenicity and sexual reproduction in eight Candida genomes". Nature 459 7247 (2009): 657-662. http://dx.doi.org/10.1038/nature08064. Published • 10.1038/nature08064 Ceppi, M.; Pereira, A.M.; Dunand-Sauthier, I.; Barras, E.; Reith, W.; Santos, M.A.; Pierre, P.. "MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells". Proceedings of the National Academy of Sciences of the United States of America 106 8 (2009): 2735-2740. http://www.scopus.com/inward/record.url?eid=2-s2.0-62449173209&partnerID=MN8TOARS. 10.1073/pnas.0811073106 Silva, R.M.; Duarte, I.C.N.; Paredes, J.A.; Lima-Costa, T.; Perrot, M.; Boucherie, H.; Goodfellow, B.J.; et al. "The yeast PNC1 longevity gene is up-regulated by mRNA mistranslation". PLoS ONE 4 4 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-65449173889&partnerID=MN8TOARS. 10.1371/journal.pone.0005212 Soares, A.R.; Pereira, P.M.; Santos, B.; Egas, C.; Gomes, A.C.; Arrais, J.; Oliveira, J.L.; Moura, G.R.; Santos, M.A.S.. "Parallel DNA pyrosequencing unveils new zebrafish microRNAs". BMC Genomics 10 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-65949098165&partnerID=MN8TOARS. 10.1186/1471-2164-10-195 Vieira, O.V.; Hartmann, D.O.; Cardoso, C.M.P.; Oberdoerfer, D.; Baptista, M.; Santos, M.A.S.; Almeida, L.; Ramalho-Santos, J.; Vaz, W.L.C.. "Surfactants as microbicides and contraceptive agents: A systematic In Vitro study". PLoS ONE 3 8 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-51449104764&partnerID=MN8TOARS. 10.1371/journal.pone.0002913 Carreto, L.; Eiriz, M.F.; Gomes, A.C.; Pereira, P.M.; Schuller, D.; Santos, M.A.S.. "Comparative genomics of wild type yeast strains unveils important genome diversity". BMC Genomics 9 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-57049101718&partnerID=MN8TOARS. 10.1186/1471-2164-9-524 Silva, Raquel M; Paredes, João A; Moura, Gabriela; Manadas, Bruno; Lima-Costa, Tatiana; Rocha, Rita; Miranda, Isabel; et al. "Critical roles for a genetic code alteration in the evolution of the genus Candida". The EMBO Journal 26 21 (2007): 4555-4565. http://dx.doi.org/10.1038/sj.emboj.7601876. Published • 10.1038/sj.emboj.7601876 Perrot, Michel; Guieysse-Peugeot, Anne-Laure; Massoni, Aurélie; Espagne, Christelle; Claverol, Stéphane; Silva, Raquel Monteiro; Jenö, Paul; et al. "Yeast proteome map (update 2006)". PROTEOMICS 7 7 (2007): 1117-1120. http://dx.doi.org/10.1002/pmic.200600952. Published • 10.1002/pmic.200600952 Santos, Manuel; Arrais, Joel; Santos, Bruno; Fernandes, João; Carreto, Laura; Oliveira, José Luis. "GeneBrowser: an approach for integration and functional classification of genomic data". Journal of Integrative Bioinformatics 4 3 (2007): http://dx.doi.org/10.1515/jib-2007-82. Published • https://doi.org/10.1515/jib-2007-82 Moura, G.; Pinheiro, M.; Arrais, J.; Gomes, A.C.; Carreto, L.; Freitas, A.; Oliveira, J.L.; Santos, M.A.S.. "Large scale comparative codon-pair context analysis unveils general rules that fine-tune evolution of mRNA primary structure". PLoS ONE 2 9 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-39449087192&partnerID=MN8TOARS. 10.1371/journal.pone.0000847 Gomes, A.C.; Miranda, I.; Silva, R.M.; Moura, G.R.; Thomas, B.; Akoulitchev, A.; Santos, M.A.S.; et al. "A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicans". Genome Biology 8 10 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-39149086991&partnerID=MN8TOARS. 10.1186/gb-2007-8-10-r206 Moura, G.R.; Lousado, J.P.; Pinheiro, M.; Carreto, L.; Silva, R.M.; Oliveira, J.L.; Santos, M.A.S.. "Codon-triplet context unveils unique features of the Candida albicans protein coding genome". BMC Genomics 8 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-39149103111&partnerID=MN8TOARS. 10.1186/1471-2164-8-444 Gomes, A.C.; Costa, T.; Carreto, L.; Santos, M.A.. "The molecular mechanism of evolution of changes in the genetic code". Molekuliarnaia biologiia. 40 4 (2006): 634-639. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749060498&partnerID=MN8TOARS. Gomes, A. C.; Costa, T.; Carreto, L.; Santos, Manuel. "On the molecular mechanism of the evolution of genetic code alterations". Molecular Biology 40 4 (2006): 564-569. http://dx.doi.org/10.1134/s002689330604008x. Published • 10.1134/s002689330604008x Gomes, A.C.; Costa, T.; Carreto, L.; Santos, M.A.S.. "On the molecular mechanism of the evolution of genetic code alterations". Molecular Biology 40 4 (2006): 564-569. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747090648&partnerID=MN8TOARS. 10.1134/S002689330604008X Miranda, I.; Silva, R.; Santos, M.A.S.. "Evolution of the genetic code in yeasts". Yeast 23 3 (2006): 203-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645126396&partnerID=MN8TOARS. 10.1002/yea.1350 Nogueira, C.; Santos, Manuel; Vilarinho, L.. "Molecular investigation in 20 patients with mitochondrial cytopathies". Nascer e Crescer 14 4 (2005): 277-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645302108&partnerID=MN8TOARS. Published Moura, G.; Pinheiro, M.; Silva, R.; Miranda, I.; Afreixo, V.; Dias, G.; Freitas, A.; Oliveira, J.L.; Santos, M.A.. "Comparative context analysis of codon pairs on an ORFeome scale.". Genome biology 6 3 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-33644889434&partnerID=MN8TOARS. Empadinhas, N.; Albuquerque, L.; Costa, J.; Zinder, S. H.; Santos, Manuel; Santos, H.; da Costa, M. S.; et al. "A Gene from the Mesophilic Bacterium Dehalococcoides ethenogenes Encodes a Novel Mannosylglycerate Synthase". Journal of Bacteriology 186 13 (2004): 4075-4084. http://dx.doi.org/10.1128/jb.186.13.4075-4084.2004. Published • 10.1128/jb.186.13.4075-4084.2004 Santos, Manuel; Moura, Gabriela; Massey, Steven E; Tuite, Mick F. "Driving change: the evolution of alternative genetic codes". Trends in Genetics 20 2 (2004): 95-102. http://dx.doi.org/10.1016/j.tig.2003.12.009. Published • 10.1016/j.tig.2003.12.009 Silva, R. M.; Miranda, Isabel; Moura, Gabriela; Santos, Manuel. "Yeast as a model organism for studying the evolution of nonstandard genetic codes". Briefings in Functional Genomics and Proteomics 3 1 (2004): 35-46. http://dx.doi.org/10.1093/bfgp/3.1.35. Published • 10.1093/bfgp/3.1.35 Afreixo, V.; Pinheiro, M.; Oliveira, J.L.; Moura, Gabriela; Santos, Manuel; Freitas, A.. "Association between genetic symbols". Cadernos de Matemática 4 (2004): 1-25. Published Massey, S. E.; Moura, Gabriela; Beltrão, P.; Almeida, R.; Garey1, J. R.; Tuite, M.F.; Santos, Manuel. "Comparative Evolutionary Genomics Unveils the Molecular Mechanism of Reassignment of the CTG Codon in Candida spp.". Genome Research 13 4 (2003): 544-557. http://dx.doi.org/10.1101/gr.811003. Published • 10.1101/gr.811003 Pinheiro, M.; Dias, G.; Afreixo, V.; Valente, A.; Moura, Gabriela; Santos, Manuel; Oliveira, J.L.. "Sistema bioinformático para análise do mecanismo molecular de descodificação da informação genética". 4 (2003): 88-96. Published Moura, Gabriela; Miranda, Isabel; Cheesman, Caroline; Tuite, Mick F.; Santos, Manuel. "Stop codon decoding in Candida albicans: from non-standard back to standard". Yeast 19 9 (2002): 727-733. http://dx.doi.org/10.1002/yea.874. Published • 10.1002/yea.874 O'Sullivan, Justin M.; Mihr, Marian J.; Santos, Manuel; Tuite, Mick F.; O'Sullivan, J.M.; Mihr, M.J.; Santos, M.A.S.; Tuite, M.F.. "Seryl-tRNA synthetase is not responsible for the evolution of CUG codon reassignment in Candida albicans". Yeast 18 4 (2001): 313-322. http://dx.doi.org/10.1002/1097-0061(20010315)18:4<313::aid-yea673>3.0.co;2-7. Published • 10.1002/1097-0061(20010315)18:4<313::aid-yea673>3.0.co;2-7 Santos, J.M.; Silva, R.M.; Domingues, P.; Amado, F.; Santos, Manuel. "Genómica Funcional em Aveiro". 68 (2001): 13-18. Published O'Sullivan, J.M.; Mihr, M.J.; Santos, M.A.S.; Tuite, M.F.; O'Sullivan, Justin M.; Mihr, Marian J.; Santos, Manuel; Tuite, Mick F.. "The Candida albicans gene encoding the cytoplasmic leucyl-tRNA synthetase: Implications for the evolution of CUG codon reassignment". Gene 275 1 (2001): 133-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035812289&partnerID=MN8TOARS. Published • 10.1016/S0378-1119(01)00632-1 Perreau, Victoria M; Keith, Gerard; Holmes, W.Mike; Przykorska, Anna; Santos, Manuel; Tuite, Mick F. "The Candida albicans CUG-decoding ser-tRNA has an atypical anticodon stem-loop structure". Journal of Molecular Biology 293 5 (1999): 1039-1053. http://dx.doi.org/10.1006/jmbi.1999.3209. Published • 10.1006/jmbi.1999.3209 Santos, Manuel; Cheesman, Caroline; Costa, Vitor; Moradas-Ferreira, Pedro; Tuite, Mick F.. "Selective advantages created by codon ambiguity allowed for the evolution of an alternative genetic code in Candida spp.". Molecular Microbiology 31 3 (1999): 937-947. http://dx.doi.org/10.1046/j.1365-2958.1999.01233.x. Published • 10.1046/j.1365-2958.1999.01233.x Santos, Manuel; Ueda, Takuya; Watanabe, Kimitsuna; Tuite, Mick F.. "The non-standard genetic code of Candida spp.: an evolving genetic code or a novel mechanism for adaptation?". Molecular Microbiology 26 3 (1997): 423-431. http://dx.doi.org/10.1046/j.1365-2958.1997.5891961.x. Published • 10.1046/j.1365-2958.1997.5891961.x Perreau, Victoria M.; Santos, Manuel; Tuite, Mick F.. "Beta, a novel repetitive DNA element associated with tRNA genes in the pathogenic yeast Candida albicans". Molecular Microbiology 25 02 (1997): 229-236. http://dx.doi.org/10.1046/j.1365-2958.1997.4521816.x. Published • 10.1046/j.1365-2958.1997.4521816.x Santos, M.A.S.; Perreau, V.M.; Tuite, M.F.; Santos, Manuel; Perreau, V. M.; Tuite, M. F.. "Transfer RNA structural change is a key element in the reassignment of the CUG codon in Candida albicans". EMBO Journal 15 18 (1996): 5060-5068. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029816377&partnerID=MN8TOARS. Published • 10.1002/j.1460-2075.1996.tb00886.x Tuite, M.F.; Santos, M.A.S.; Santos, Manuel. "Codon reassignment in Candida species: An evolutionary conundrum". Biochimie 78 11-12 (1996): 993-999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030437176&partnerID=MN8TOARS. Published • 10.1016/S0300-9084(97)86722-3 Santos, Manuel; Tuite, Mick F.. "The CUG codon is decoded in vivo as serine and not leucine in Candida albicans". Nucleic Acids Research 23 9 (1995): 1481-1486. http://dx.doi.org/10.1093/nar/23.9.1481. Published • 10.1093/nar/23.9.1481 Santos, M.A.S.; El-Adlouni, C.; Cox, A.D.; Luz, J.M.; Keith, G.; Tuite, M.F.. "Transfer RNA profiling: A new method for the identification of pathogenic Candida species". Yeast 10 5 (1994): 625-636. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028237559&partnerID=MN8TOARS. 10.1002/yea.320100507 Santos, Manuel; Tuite, Mick F.. "New insights into mRNA decoding — implications for heterologous protein synthesis". Trends in Biotechnology 11 12 (1993): 500-505. http://dx.doi.org/10.1016/0167-7799(93)90028-8. Published • 10.1016/0167-7799(93)90028-8 Santos, Manuel; Keith, G.; Tuite, M.F.. "Non-standard translational events in Candida albicans mediated by an unusual seryl-tRNA with a 5'-CAG-3' (leucine) anticodon.". The EMBO Journal 12 2 (1993): 607-616. http://dx.doi.org/10.1002/j.1460-2075.1993.tb05693.x. Published • 10.1002/j.1460-2075.1993.tb05693.x Glasser, A.-L.; El Adlouni, C.; Keith, G.; Sochacka, E.; Malkiewicz, A.; Santos, M.; Tuite, M.F.; et al. "Presence and coding properties of 2'-O-methyl-5-carbamoylmethyluridine (ncm⁵Um) in the wobble position of the anticodon of tRNA^Leu (UAA) from brewer's yeast". FEBS Letters* 314 3 (1992): 381-385. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026677843&partnerID=MN8TOARS. Published • 10.1016/0014-5793(92)81510-S Colthurst, David R.; Santos, Manuel; Grant, Chris M.; Tuite, Mick F.. "Candida albicans and three other Candida species contain an elongation factor structurally and functionally analogous to elongation factor 3". FEMS Microbiology Letters 80 1 (1991): 45-50. http://dx.doi.org/10.1111/j.1574-6968.1991.tb04634.x. Published • 10.1111/j.1574-6968.1991.tb04634.x Santos, M.; Colthurst, D.R.; Wills, N.; McLaughlin, C.S.; Tuite, M.F.; Santos, Manuel; Colthurst, D. R.; McLaughlin, C. S.; Tuite, M. F.. "Efficient translation of the UAG termination codon in Candida species". Current Genetics 17 6 (1990): 487-491. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025335761&partnerID=MN8TOARS. Published • 10.1007/BF00313076 Santos, Manuel; Williams, Ralph A.D.; Da Costa, Milton S.; Santos, M.A.; Williams, R.A.D.; Da Costa, M.S.. "Numerical Taxonomy of Thermus Isolates from Hot Springs in Portugal". Systematic and Applied Microbiology 12 3 (1989): 310-315. http://dx.doi.org/10.1016/s0723-2020(89)80079-7. Published • 10.1016/s0723-2020(89)80079-7
Preprint	Correia, Inês; Oliveira, Carla; Reis, Andreia; Guimarães, Ana Rita; Aveiro, Susana; Domingues, Pedro; Bezerra, Ana Rita; et al. "A proteogenomic pipeline for the analysis of protein biosynthesis errors in the human pathogen Candida albicans". 2023. http://dx.doi.org/10.1101/2023.10.31.564356. 10.1101/2023.10.31.564356 Oliveira, Carla; Guimarães, Ana Rita; Correia, Inês; Sousa, Inês; Poim, Ana; Rocha, Sílvia M.; Moura, Gabriela; Santos, Manuel A. S.; Bezerra, Ana Rita. "Filamentation in Candida albicans is modulated by adaptive translation of farnesol signalling genes". 2021. http://dx.doi.org/10.1101/2021.01.20.427544. 10.1101/2021.01.20.427544
Thesis / Dissertation	Santos, Manuel. "Molecular characterization of a novel leucyl-tRNACAG from Candida albicans". PhD, University of Kent, 1992.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2017	The statistical proteome of Candida albicans	28th International Conference on Yeast Genetics and Molecular Biology-Yeast2017
2017	Genetic code ambiguity is a major source of genome instability in C. albicans genome	FEBS3+, 1st joint meeting of the French-Portuguese –Spanish Biochemical and Molecular Biology Societies
2017	Comparative genomics of a Candida genetic code alteration	MicroBiotec’2007
2016/02	Understanding tolerance to protein mistranslation and aggregation	Nucleic Acids in Medicine Worksshop HARC2016
2016	Identification of novel regulators of protein synthesis fidelity and aggregation using high contente screens	EMBL conference : The epitranscriptome
2015/06/24	Misacylation events contribute to tumor progression in vivo	I Simpósio de Pós-Graduação em Biomedicina
2015/05	Misreading tRNAs promote tumor progression in vivo	XXXIX Jornadas Portuguesas da Genética
2015/03/03	The statistical proteome of the pathogenic fungus Candida albicans	University of Aberdeen
2015/03/02	Monitoring protein sinthesis accuracy using mass spectrometry and advanced bioinformatics	BBSRC-BioProNet Workshop on “Protein Authenticity”, Charles Darwin House
2015/02/27	Protein mistranslation in Candid albicans School of Biosciences	University of Kent
2015	Misreading Serine tRNAs accelerate tumor progression in vivo	IV Encontro Nacional de Pós-Graduação em Ciências Biológicas
2014/10	RNA diseases	Fundamentals in Genetics, Development and Neoplasia of the International Postgraduate Programme, Life and Health Sciences Research Institute (ICVS), School of Health Sciences (ECS)
2014/05	Reversion of a genetic code alteration in the human pathogen Candida albicans	114th General Meeting, American Society for Microbiology
2014/02	Monitoring yeast evolutionary trajectories using DNA microarrays and NGS	Agilent’s First AgBio User Meeting
2013/12	Fungal statistical proteomes: can they shake current concepts of the gene?	MicroBiotec’13
2013/12	Statistical proteomes: can they shake current concepts of the gene?	Gene translation: fidelity and quality control. Barcelona BioMed Conferences
2013/10	Diseases associated with protein mistranslation	Fundamentals of Genetics, Development and Neoplasia, 5th edition
2013/06	Invited lecture in Cell Genetics	XXXVIII Jornadas Portuguesas de Genética
2013/06	Genome mistranslation induces proteome aggregation and oxidative stress in zebrafish embryos	XXXVIII Jornadas Portuguesas de Genética
2013/05	Candida albicans has a statistical proteome generated through variable incorporation of Leu and Ser at CUG sites	15th FEBS Advanced Lecture Course on Human Fungal Pathogens
2013/03/22	Statistical proteomes: can they shake the foundations of current biological concepts?	Conferência de Inverno 2013
2012/12	The molecular mechanism of evolution of a fungal genetic code alteration	XXIV tRNA Conference (formerly tRNA Workshop)
2012/12	Genetic code engineering generates genetic and phenotypic diversity in the human pathogen Candida albicans	XXIV tRNA Conference
2012/10	Reversion of a genetic code alteration generates genetic and phenotypic diversity in Candida albicans	EMBO Conference Series “Experimental Approaches to Evolution and Ecology using yeast”
2012/09/27	The national Facility for DNA Microarrays	User Meeting de Genómica
2012/09/27	MicroRNAs in human cancer	User Meeting de Genómica
2012/09	The molecular mechanism of evolution of a fungal genetic code alteration	FEBS International Workshop “New Developments in RNA Biology”
2012/05	Zebrafish as a model system of proteotoxic stress induced by mRNA mistranslation. . Lisboa, 28-30 Maio 2012.	XXXVII Jornadas Portuguesas de Genética
2012/05	Genetic code engineering generates genetic and phenotypic diversity in the human pathogen Candida albicans	XXXVII Jornadas Portuguesas de Genética
2012/04/20	Protein synthesis and drug resistance	6th Biochemistry Day
2012/02/29	The evolvability of the microbial genetic code	Seminários em Microbiologia Molecular
2012/02/09	Genetic code engineering: an insightful tour through synthetic biology, genome evolution and the origin of life	António V. Xavier’s Seminars 2011-2012
2012/02	Roles of mistranslation on the evolution of fungal drug resistance	Annual General Meeting of the European Project SYBARYS
2011/12	Microevolutionary changes of commercial Saccharomyces cerevisiae strains recovered from vineyard environments identified by comparative genome hybridization on array	MicroBiotec’11
2011/11	Translational misreading in fungi and its adaptative and evolutionary consequences	Annual Meeting of the Institute for Cellular and Molecular Medicine
2011/09	The C. albicans Seryl-tRNA synthetase is highly polymorphic	The 2011 International Symposium on Aminoacyl-tRNA Synthetases
2011/05	Molecular characterization of Candida albicans strains with a standard genetic code	4th FEBS Advanced Lecture Course, Human Fungal Pathogens, Molecular Mechanisms of Host-Pathogen Interactions and Virulence
2011	Mistranslation-driven evolution of antifungal drug resistance	XXXVI Jornadas Portuguesas de Genética
2011	Comparative genomics of commercial Saccharomyces cerevisiae isolates recovered from vineyard environments	XXXVI Jornadas Portuguesas de Genética
2011	A novel class of zebrafish small RNAs derived from transfer RNAs	XXXVI Jornadas Portuguesas de Genética
2010/12	Effects of genome mistranslation on zebrafish development	XVII Congresso Nacional de Bioquímica
2010/12	Effects of translational stress mutagenesis on the evolution of antifungal drug resistance	XVII Congresso Nacional de Bioquímica
2010/06	An application for studying tandem repeats in orthologous genes	IWPACBB – 4th International Workshop on Practical applications of Computational Biology & Bioinformatics
2010	Reversion of a genetic code alteration in the human pathogen Candida albicans	EMBO Conference Series – Experimental Approaches to Evolution and Ecology in Yeast
2010	Genome alterations in response to mRNA mistranslation in yeast	XXXV Jornadas Portuguesas de Genética
2010	A collection of indigenous Saccharomyces cerevisiae strains from appellations of origin in Portugal and France	XXXV Jornadas Portuguesas de Genética
2010	Reversion of a genetic code alteration in the human pathogen Candida albicans	23rd tRNA Workshop
2010	Important changes in genome translation in yeasts	23rd tRNA Workshop
2010	The transcriptome and the translatome of yeast mistranslating the genetic code unveil the cellular networks required for recovery of misfolded proteins	23rd tRNA Workshop
2009/11	The evolution of the genetic code	V Meeting on RNA Research in Portugal (RNA2009)
2009/11	Tackling high variability of miRNA expression in human cervical tissues	V Meeting on RNA Research in Portugal (RNA2009)
2009/06	Analysing the evolution of repetitive strands in genomes	IWPACBB – 3rd International Workshop on Practical applications of Computational Biology & Bioinformatics
2009/05	Crystal structures of the SerRS explain proteome tolerance to a genetic code alteration in Candida albicans	Third FEBS Advanced Lecture Course “Human Fungal Pathogens”
2009/05	New tools for studying the Candida albicans genetic code	Third FEBS Advanced Lecture Course “Human Fungal Pathogens”
2009/04	The impact of environmental stress on protein synthesis fidelity	VIII Department of Biology Postgraduate symposium
2009/01/23	National facility for DNA microarrays: an overview	Portuguese-British Meeting on Modulation of Programmed Cell Death and Therapeutic Targets in Cancer and Neurodegenerative Diseases
2009/01	Protein mistranslation in the Pathogenic fungus Candida albicans	Gordon Research Conference on RNA Editing
2008/10	Distinctive microRNA profiles in cervical cancer	XVI Congresso Nacional de Bioquímica
2008/10	Transcriptional and translational responses to mRNA mistranslation in yeast	XVI Congresso Nacional de Bioquímica
2008/09	Crystal structures of the SerRS explain proteome tolerance to a genetic code alteration in the human pathogen Candida albicans	aaRS2008, International Conference on Aminoacyl-tRNA Synthetases
2008/06	Genesplit – uma aplicação para o estudo de associações de codões e de aminoácidos em ORFeomas	CISTI – 3rd Iberian Conference on Information Systems and Technologies
2008/03	Candida albicans uses a genetic code alteration to generate proteome diversity	ASM Conferences – 9th Candida and Candidiasis
2008	Exploiting codon-triplets association for genome primary structure analysis	BIOTECHNO – International Conference on Biocomputation, Bioinformatics and Biomedical Technologies, Bucareste
2007/11	Critical roles for mRNA mistranslation in the evolution of the genetic code	IV National RNA Meeting (RNA 2007)
2007/11	MicroRNA signatures in human cervical cancer	IV National RNA Meeting (RNA 2007)
2007/11	mRNA primary structure features that influence decoding error	IV National RNA Meeting (RNA 2007)
2007/10	The role of tRNA mischarging in the evolution of a genetic code alteration in Candida	ESF-EMBO Symposium on Comparative Genomic of Eukaryotic Microorganisms
2007/10	Comparative tRNomics of a genetic code alteration	ESF-EMBO Symposium on Comparative Genomic of Eukaryotic Microorganisms
2007/06	A new biclustering criterion for the iterative signature algorithm	XI Conferencia Española y 1er Encuentro IberoAmericano de Biometría
2007	Comparison of Saccharomyces cerevisiae populations from different appelations of origin and grape varieties by microsatellite analysis	MicroBiotec’2007
2007	Comparative genome hibridization of wild type and commercial wine strains of Saccharomyces cerevisiae using DNA microarrays	MicroBiotec’2007
2006/12	National facility for DNA microarrays	XV Congresso Nacional de Bioquímica (NCB2006)
2006/12	A tool to unveil the evolution of the tRNA(CAG) in yeasts	XV Congresso Nacional de Bioquímica (NCB2006)
2006/12	The role of mRNA mistranslation on cell degeneration and aging	XV Congresso Nacional de Bioquímica (NCB2006)
2006/12	Whole genome shotgun mapping of Rubrobacter radiotolerans	XV Congresso Nacional de Bioquímica (NCB2006)
2006/12	Large scale comparative codon context analysis unveils novel rules governing gene evolution	III National Meeting on RNA Biology (RNA 2006)
2006/10	Molecular evolution of a genetic code alteration in Candida	aaRS2006, International Conference on Aminoacyl-tRNA Synthetases
2006/09/30	ISA: um algoritmo de “biclustering”?	XIV Congresso Anual da Sociedade Portuguesa de Estatística
2005/12	Functional characterization of a genetic code alteration in the human pathogen Candida albicans	21th international tRNA Workshop (tRNA-2005)
2005/11	Genetic code reassignment in fungi: genomic view and consequences	ESF-EMBO Symposium on Comparative Genomics of Eukaryotic Microorganisms
2005/09	Activation of the stress response by mRNA mistranslation generates phenotypic diversity in yeast	CSSi – 2nd International Congress on Stress Responses in Biology and Medicine
2005/09	High level mistranslation of a reassigned CUG codon in the human pathogen Candida albicans	EMBO Conference on Protein Synthesis and Translational Control
2005/05	Impact of CUG ambiguity on Candida albicans cell Biology- A genomic approach	FEBS Advanced Lecture Course on “Human Fungal Pathogens: Molecular Mechanisms of Host-Pathogen Interactions and Virulence”
2005/04	Mistranslation of the CUG codon generates phenotypic diversity in Candida albicans	BYG2005, British Yeast Group Meeting
2005	Integrating proteomics and transcriptomics data	Proteomics Workshop: from sample preparation to protein identification
2004/12	Comparative codon context analysis in complete genomes unveils new decoding rules in yeast	XIV Congresso Nacional de Bioquímica
2004/09/30	Informação genética – dos genes às proteínas	VI Congresso Nacional da Associação Portuguesa de Professores de Biologia e Geologia
2004/05	Molecular characterization of Saccharomyces cerevisiae cells expressing genetic code ambiguity	XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden
2004/05	A major role for CUG ambiguity in Candida biology and evolution. . Aveiro, 13-15 Maio 2004.	XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden
2004/05	Decoding ambiguity in the CUG codon in Candida albicans. . Aveiro, 13-15 Maio 2004.	XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden
2004/05	Genome duplication and destabilization induced by mRNA decoding ambiguity in both S. cerevisiae and Candida albicans	XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden
2004/05	Implementation of a DNA-microarray platform for yeast gene expression, genome diversity and evolution and molecular diagnostics. . Aveiro, 13-15 Maio 2004.	XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden
2004/05	Genome scale codon context analysis for Saccharomyces cerevisiae and Candida albicans	XII Jornadas de Biologia de Leveduras Prof. Nicolau van Uden
2004/03	A novel and critical role for a genetic code change in the evolution of the genus Candida	ASM Conferences – Candida and Candidiasis (7th)
2004/02/20	A novel and critical role for a genetic code change in the evolution of the genus Candida	Institut de Biologie Moléculaire et cellulaire
2003/11/17	Proteome destabilization by genetic ambiguity in S. cerevisiae	Functional Genomics and Proteomics – 1st Annual Meeting of Portuguese Proteomics Netwrok – ProCura
2003/10	Proteomics: technologies	Genomics and Proteomics Biophysical Perspectives – 5th short course of the Portuguese Biophysical Society
2003/09	Proteome destabilization by a genetic code change in Candida spp.	Luso-Spanish workshop on the structure and function of proteins
2003/09	A novel role for a genetic code change in the evolution of the genus Candida	Human fungal pathogens: Euroconference on Host-pathogen Interactions
2003/09	Evolution of the genetic code	EMBO Young Investigator Programme PhD Course
2003/07	Comparative evolutionary genomics of CUG reassignment in Candida species. , Gotemburgo, Suécia, 7-12 Julho.	XXIst International Conference on the Yeast Genetics and Molecular Biology
2003/05	The effect of ambiguous CUG decoding in C. albicans evolution and physiology	11ª Jornadas de Biologia de Leveduras Professor Nicolau Van Uden
2003/05	The evolution of the Candida CUG codon reassignment	3º EMBO Young Investigator Meeting
2003	A genetic code alteration has driven evolution of the genus Candida	Micro’2003 Congresso Nacional de Microbiologia
2002/12	A functional genomics approach to the evolution of alternative genetic codes	XIII Congresso Nacional de Bioquímica
2002/05	Elucidating the role of genetic code ambiguity in Candida albicans physiology and genome evolution	10ªs Jornadas de Biologia de Leveduras Professor Nicolau Van Uden
2002/04	The role of genetic code alterations on genome evolution	2nd EMBO Young Investigator Meeting
2002/04	Study of codon context on complete genomes	I Post-Graduation Symposium in Biosciences
2002/03	Post-génomique et proteómique- les nouveux modèles cultureles	Journées Albert Netter: Génétique et Biotechnologie en Gynecologie, du diagnostic a la thérapeutique
2001/12	The effect of genetic code ambiguity on Saccharomyces cerevisiae gene expression	Congresso Nacional de Microbiologia- Micro 2001
2001/09/03	A genomics approach to the evolution of alternative genetic codes	International Institute of Molecular and Cell Biology
2001/09	On the evolution of alternative genetic codes in microorganisms	XVIII Congresso de la Sociedad Española de Microbiologia (SEM2001)
2001/06	Codon usage in Candida albicans	The 7th Congress of the European Confederation of Medical Mycology- ECMM
1999/06/12	The evolution of non-standard genetic codes	Summer seminars in Biology
1998/11	Gene expression re-programming by genetic code ambiguity in Saccharomyces cerevisiae	XI Congresso Nacional de Bioquímica
1998/11	Investigar com organismos manipulados geneticamente	Agentes Biológicos: Segurança e Saúde no Ambiente de Trabalho (Biohazard)
1998/04	Can C. albicans exploit its alternative genetic code as a novel mechanism for adaptation?	6as Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
1998	On the molecular mechanism of an alternative genetic code in Candida albicans	Dept. Biosciences, University of Kent
1998	The role of genetic code changes in genome evolution	Department of Molecular and Cell Biology
1998	The role of genetic code changes in genome evolution	Instituto Gulbenkian de Ciência
1997/07	Mistranslation of the leucine-CUG codon as serine by a C. albicans ser-tRNA(CAG) activates the general stress response in S. cerevisiae	Translation UK 1997
1997/05	tRNA structural change is a key element in the reassignment of the CUG codon from leucine to serine in Candida albicans	17th International tRNA Workshop
1997/03	Expression of a novel Candida albicans seryl-tRNA(CAG) in Saccharomyces cerevisiae induces the stress response: implications for the evolution of Candida pathogenesis	Microbial Response to Stress: What’s new and how can it be applied?
1996/07	Transfer RNA structural change is a key element in the reassignment of the CUG codon in Candida albicans	Translation UK ’96
1995	The nature and evolution of the genetic code in Candida species	Meeting of the Society for General Microbiology
1994	The molecular basis of an alternative genetic code in the human pathogenic yeast Candida albicans. , University of Kent, UK	Research School of Biosciences
1993/05	Unusual decoding properties of a tRNA from Candida albicans	Alternate readings of the genetic code
1993	Breakdown in the genetic code in Candida albicans mediated by a unique seryl-tRNA with a 5'-CAG-3' leucine anticodon	15th International tRNA workshop

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2017 - Current	Unravelling the roles of proteotoxic stress on genome diversification and disease Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 - Current	The role of protein mistranslation in fungal pathogenesis Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 - Current	Gene expression variation across the lifespan in mice Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 - Current	Recoding the Saccharomyces cerevisiae genome Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 - Current	Candida albicans gene mistranslation as a modulator of host-pathogen interactions and pathogenesis Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 - Current	Consequences of reciprocal control of mistranslation during antifungal immunity Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - Current	Genotipagem da Vitis vinifera Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2012 - Current	Isolamento, caracterização e estudo in vitro da interacção de microrganismos presentes em Vitis vinifera Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2012 - Current	Identification of development TFs binding sites in Nematostella vectensis genome using ChiP-seq Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2012 - Current	Elucidating the function of a new class of small non-coding RNAs in zebrafish Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2010 - Current	The cellular response to mRNA mistranslation in mammalian cells Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - Current	Caracterização molecular das leveduras vínicas endógenas da Bairrada Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - Current	Estudo da diversidade de Vitis vinifera variedade Baga nas vinhas da Bairrada Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - Current	Estudo dos genes mitocondriais do complexo IV em 31 doentes Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - Current	Estudo fenotípico de leveduras vínicas endógenas da Bairrada Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - Current	Estudo do correcto carregamento dos tRNAs utilizando sequenciação massiva paralela Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2007 - Current	Desenvolvimento de um método para identificação de inibidores de proteases baseado em leveduras Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2007 - Current	Acção do stresse oxidativo e fármacos no desenvolvimento e progressão do cancro da próstata Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2006 - Current	Transcriptional regulation of eukaryotic genome Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2005 - Current	Studying amyloid formation in yeast Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2001 - Current	Estudo do efeito da ambiguidade do código genético no desenvolvimento de Drosophila melanogaster Supervisor	Biologia (Degree) Universidade de Aveiro Departamento de Biologia, Portugal
2017 - 2018	Identificação de factores de transcrição envolvidos no processo de mistranslation em Candida albicans Supervisor	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 - 2018	Identification of novel regulators of protein synthesis fidelity using high content genetic screens Co-supervisor	Programa Doutoral em Biomedicina (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2017	Unravelling the celular networks that regulate proteotoxic stress Supervisor	Programa Doutoral em Biomedicina (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2017	Unravelling the roles of statistical proteomes in human cancer Supervisor	Programa Doutoral em Biomedicina (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 - 2016	Protein aggregation and proteostasis in aging mice Co-supervisor	Biomedicina Molecular (Master) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2011 - 2015	Elucidating the role of genome mistranslation on mitochondrial dysfunction Supervisor	Programa Doutoral em Biomedicina (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2014	Efeitos de erros de tradução no peixe zebra Co-supervisor	Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, Portugal
2012 - 2014	Evolution of antifungal drug resistance in Candida albicans Co-supervisor	Biologia Molecular e Celular (Master) Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, Portugal
2012 - 2014	Elucidating the role of the translation machinery on gene evolution Supervisor
2011 - 2013	Caracterização de uma nova classe de pequenos RNAs não codificantes, derivados de tRNAs em peixe zebra Co-supervisor	Biologia Molecular e Celular (Master) Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, Portugal
2011 - 2013	Stress proteotóxico na estabilidade do genoma humano Supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2013	Estudo do stress proteotóxico no peixe zebra Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2013	The role of mRNA mistranslation in the development of drug resistance in fungi Supervisor
2008 - 2013	Phenotypic consequences of genome mistranslation in Candida albicans Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - 2013	Molecular genomics of a genetic code alteration Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - 2013	Suppressor-tRNAs as therapeutic tools for hereditary cancer syndromes: HDGC as a model system Co-supervisor	Programa Doutoral em Biomedicina (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2007 - 2013	The study of mRNA mistranslation in mammalian cells Supervisor
2010 - 2012	Erros de tradução no mRNA e instabilidade genómica Co-supervisor	Biotecnologia Molecular (Master) Universidade de Aveiro Departamento de Química, Portugal
2010 - 2012	A base genética da longevidade em Drosophila americana Co-supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2010 - 2012	Estudo dos factores que influenciam o stress proteotóxico em levedura Co-supervisor	Biomedicina Molecular (Master) Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, Portugal
2010 - 2012	Cianobactérias marinhas: avaliação do potencial anticancerígeno Co-supervisor	Biotecnologia Molecular (Master) Universidade de Aveiro Departamento de Química, Portugal
2010 - 2012	Quantificação de erros de incorporação em proteínas recombinantes Supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2010 - 2012	Biodiversidade de estirpes de S. cerevisiae vínicas em Portugal Co-supervisor	Biologia Aplicada (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - 2012	The development of bioinformatics and molecular tools to study the effects of codon context on mRNA translation fidelity Supervisor
2007 - 2012	Cellular responses to genome mistranslation Supervisor	Programa Doutoral em Bioquímica (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2007 - 2012	The role of environmental stress on protein synthesis fidelity Supervisor	Programa Doutoral em Bioquímica (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2006 - 2012	The involvement of microRNAs in gastric cancer Co-supervisor	Programa Doutoral em Biomedicina (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2011	Targeting protein synthesis in the apicoplast and cytoplasm of Plasmodium Supervisor
2009 - 2011	Erros de tradução do mRNA em Candida albicans Supervisor	Biologia Aplicada (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2011	Erros de tradução e estabilidade telomérica Supervisor	Biologia Aplicada (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2011	Síntese de genes de novo Supervisor	Biotecnologia Molecular (Master) Universidade de Aveiro Departamento de Química, Portugal
2009 - 2011	Susceptibilidade de Candida albicans à caspofungina e mutações de FKS1 Co-supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2011	Erros de tradução do mRNA em Saccharomyces cerevisiae Supervisor	Biologia Aplicada (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2011	Toxicidade de aminoácidos em peixe-zebra Supervisor	Biologia Aplicada (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2011	O Yap1 no stress causado pelo excesso de cobalto em S. cerevisiae Co-supervisor	Biotecnologia (Master) Universidade de Aveiro Departamento de Química, Portugal
2009 - 2011	Factores genéticos de risco para acidente vascular cerebral jovem Co-supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2009 - 2011	Resistência a antifúngicos gerada por erros na tradução em levedura Supervisor	Biotecnologia (Master) Universidade de Aveiro Departamento de Química, Portugal
2009 - 2011	Síntese proteica aberrante em células humanas HEK293FT Supervisor	Biologia Aplicada (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2006 - 2011	Zebrafish small RNAs: unraveling expression and functions of novel microRNAs and tRNA fragments in a vertebrate model Supervisor	Programa Doutoral em Farmácia, especialidade de Biologia Celular e Molecular (PhD) Universidade de Coimbra Faculdade de Farmácia, Portugal
2006 - 2011	Molecular reconstruction of a genetic code alteration Supervisor	Programa Doutoral em Bioquímica (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2005 - 2011	Analysis of the translation factor genes involved in a genetic code change in Candida albicans Supervisor
2008 - 2010	Estudo molecular da epilepsia mioclonica progressiva Unverricht-Lundborg Co-supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2008 - 2010	Expressão de miRNAs no cérebro de Danio rerio exposto a etanol Supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2005 - 2010	Sistema computacional para o estudo da estrutura primária e redesenho de genes Co-supervisor	Programa Doutoral em Engenharia Informática (PhD) Universidade de Aveiro Departamento de Electrónica Telecomunicações e Informática, Portugal
2005 - 2010	Molecular study of cell degeneration and evolution induced by mRNA mistranslation Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2005 - 2009	Implementation of a National Facility for DNA-Microarrays Supervisor
2006 - 2008	Dinâmica populacional de leveduras na fermentação de mostos vínicos Supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2006 - 2008	Desenvolvimento de um sistema de diagnóstico molecular para microrganismos enológicos Supervisor	Biologia Molecular e Celular (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2006 - 2008	Detecção de bactérias periodontais e análise de polimorfismos da IL1 Co-supervisor	Engenharia Biomédica (Master) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2002 - 2008	Molecular evolution of a genetic code alteration Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2005 - 2007	Caracterização molecular de estirpes autóctones de Saccharomyces cerevisiae Supervisor	Microbiologia (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2005 - 2007	Quitosano para vectorização de genes: do tráfego intracelular à expressão genética Co-supervisor	Engenharia Biomédica (Master) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2002 - 2007	Computational tools for the study of cellular networks Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2002 - 2007	Developing bioinformatics and molecular tools for codon context analysis on a genomic scale Supervisor
2000 - 2006	Molecular Study of a genetic code alteration in C. albicans Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2003 - 2005	Sistema de rastreio de doenças metabólicas Co-supervisor	Engenharia Electrónica e Telecomunicações (Master) Universidade de Aveiro Departamento de Electrónica Telecomunicações e Informática, Portugal
2003 - 2005	Análise funcional do domínio de ligação aos microtúbulos da proteína MAST Co-supervisor	Métodos Biomoleculares Avançados (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2003 - 2005	Desenho de chips de DNA para diagnóstico de doenças infecciosas fúngicas Supervisor	Métodos Biomoleculares Avançados (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2002 - 2005	Analysis of the translation factor genes involved in a genetic code change in Candida albicans Supervisor
2000 - 2005	Molecular reconstruction of a genetic code alteration Supervisor	Programa Doutoral em Biologia (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2002 - 2004	Inibição da replicação do vírus da imunodeficiência humana por anticorpos de domínio único VH derivados de coelho Co-supervisor	Métodos Biomoleculares Avançados (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2001 - 2003	Estudo de tRNAs virais codificados pelo genoma do virus MHV-68 Supervisor	Métodos Biomoleculares Avançados (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2001 - 2003	Elucidation of the identity elements of a seryl-tRNACAG from Candida albicans Supervisor
2000 - 2002	Investigação molecular em 20 doentes com citopatia mitocondrial Supervisor	Métodos Biomoleculares Avançados (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2000 - 2002	Study of the role of a genetic code alteration in the evolution of new phenotypes in Candida albicans Supervisor
2000 - 2001	Developing bioinformatics and molecular tools for codon context analysis on a genomic scale Supervisor
1999 - 2001	Impacto da ambiguidade do código genético na estrutura da parede celular e propriedades de adesão de Saccharomyces cerevisiae Co-supervisor	Biotecnologia-Engenharia de Bioprocessos (Master) Universidade do Minho, Portugal
1997 - 2000	Molecular study of the evolutionary pathway of reassignment of the CUG codon in Candida albicans Supervisor

Event organisation

	Event name Type of event (Role)	Institution / Organization
2018/09/23 - 2018/09/27	XXVII tRNA Conference, Strasbourg-France (2018/09/23 - 2018/09/27)
2018/06/14 - 2018/06/15	XLII Annual Meeting of the Portuguese Society of Genetics (2018/06/14 - 2018/06/15)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/06/08 - 2017/06/09	XLII Jornadas da Sociedade Portuguesa de Genética (2017/06/08 - 2017/06/09)	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/06/08 - 2017/06/09	XLI Jornadas da Sociedade Portuguesa de Genética (2017/06/08 - 2017/06/09)	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016/09/04 - 2016/09/04	XXVI tRNA Conference, Jeju-South Corea (2016/09/04 - 2016/09/04)
2016/06/29 - 2016/06/29	II simpósio de Pós-graduação em Biomedicina (2016/06/29 - 2016/06/29) Symposium (President of the Organising Committee)	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016/06/02 - 2016/06/03	XL jornadas da Sociedade Portuguesa de Genética (2016/06/02 - 2016/06/03)	Universidade de Coimbra, Portugal
2016/04/25 - 2016/04/29	Seminário : Protein synthesis and aggregation across the lifespan - 1st Edition of the MIA Summer School : Biology of Ageing – from cell to society (2016/04/25 - 2016/04/29) Seminar (Member of the Organising Committee)	Universidade de Coimbra, Portugal Newcastle University, United Kingdom
2015/06/24 - 2015/06/24	I simpósio de Pós-graduação em Biomedicina (2015/06/24 - 2015/06/24) Symposium (President of the Organising Committee)	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015/05/25 - 2015/05/27	XXXIX Jornadas da Sociedade Portuguesa de Genética (2015/05/25 - 2015/05/27)	Universidade do Minho, Portugal
2014/05/21 - 2014/05/25	XXV tRNA Conference, Kyllini-Greece (2014/05/21 - 2014/05/25)
2013/01/17 - 2013/01/17	Seminário: RNomics applied to health and disease (2013/01/17 - 2013/01/17) Seminar (Member of the Organising Committee)	Universidade de Coimbra Faculdade de Medicina, Portugal
2012/12/02 - 2012/12/06	XXIV tRNA Conference (formely tRNA Workshop), Olmué, Chile (2012/12/02 - 2012/12/06)
2012/07/09 - 2012/07/13	Seminário: Advanced Course on Protein Profiling of Microorganisms (2012/07/09 - 2012/07/13) Seminar (Member of the Organising Committee)	Universidade de Aveiro Departamento de Biologia, Portugal
2012/05/28 - 2012/05/30	XXXVII Jornadas Portuguesas de Genética, Lisboa (2012/05/28 - 2012/05/30)
2012/04/20 - 2012/04/20	6th Biochemistry Day (2012/04/20 - 2012/04/20)	Universidade de Aveiro, Portugal
2011/12/01 - 2011/12/03	MicroBiotec 2011, Braga (2011/12/01 - 2011/12/03)
2011/05/30 - 2011/06/01	XXXVI Jornadas Portuguesas de Genética, Coimbra (2011/05/30 - 2011/06/01)
2011/02/03 - 2011/02/04	SYBARIS – 2nd Annual General Meeting (2011/02/03 - 2011/02/04)	Universidade de Aveiro, Portugal
2010/12/15 - 2010/12/17	XVII Congresso Nacional de Bioquímica, Porto (2010/12/15 - 2010/12/17)
2010/12/09 - 2010/12/09	Seminário: The role of tRNA processing and tRNA function on protein aggregation and neurodegeneration. RNA regulation in neuronal, development, function and dysfunction. (2010/12/09 - 2010/12/09) Seminar (Member of the Organising Committee)	CNC.IBILI, Portugal
2010/05/31 - 2010/06/02	XXXV Jornadas Portuguesas de Genética, Braga (2010/05/31 - 2010/06/02)
2010/01/28 - 2010/02/02	23rd International tRNA Meeting – from the origin of life to biomedicine (2010/01/28 - 2010/02/02)	Universidade de Aveiro, Portugal
2009/11/05 - 2009/11/06	RNA 2009 – V meeting on RNA research in Portugal, Carcavelos (2009/11/05 - 2009/11/06)
2008/10/22 - 2008/10/25	XVI Congresso Nacional de Bioquímica, Ponta Delgada (2008/10/22 - 2008/10/25)
2008/05/13 - 2008/10/15	Aveiro Molecular Genomics Advanced Courses (2008/05/13 - 2008/10/15) Other (President of the Organising Committee)
2007/11/30 - 2007/12/02	MicroBiotec 2007, Lisboa (2007/11/30 - 2007/12/02)
2006/12/08 - 2006/12/10	XV Congresso Nacional de Bioquímica (2006/12/08 - 2006/12/10)	Universidade de Aveiro, Portugal
2006/12/07 - 2006/12/07	III Reunião Anual de Biologia do RNA (2006/12/07 - 2006/12/07)	Universidade de Aveiro, Portugal
2005/06/28 - 2005/07/01	Proteomics: from sample preparation to protein identification (2005/06/28 - 2005/07/01)	CNC.IBILI, Portugal
2004/12/02 - 2004/12/04	XIV Congresso Nacional de Bioquímica, Vilamoura (2004/12/02 - 2004/12/04)
2004/05/13 - 2004/05/15	XII Jornadas de Biologia de Leveduras: professor Nicolau Van Uden (2004/05/13 - 2004/05/15)	Universidade de Aveiro, Portugal
2003/10/17 - 2003/10/19	Genomics and Proteomics - Biophysical Perspectives, Casa do Brasil, Santarém; Curso organizado em colaboração com a Sociedade Portuguesa de Biofísica (2003/10/17 - 2003/10/19)
2003/09/03 - 2003/09/09	EMBO Young Investigator Programme PhD Course: Spot Lights on Current Biology (2003/09/03 - 2003/09/09)
2002/12/17 - 2002/12/17	Acção de formação: Introdução às tecnologias de análise do genoma: transcriptoma e bioinformática lecionada no âmbito do curso prático avançado de biologia molecular (2002/12/17 - 2002/12/17)
2002/12/05 - 2002/12/07	XIII Congresso Nacional de Bioquímica, Lisboa (2002/12/05 - 2002/12/07)
2002/09/07 - 2002/09/13	Seminário: New methodologies for proteome analysis. FEBS Lecture Course: Advanced technologies for metabolic engineering in biotechnology and Medicine (2002/09/07 - 2002/09/13) Seminar (Member of the Organising Committee)
2002/02/11 - 2002/02/15	Proteomics and bioinformatics methodologies (2002/02/11 - 2002/02/15)
2001/09/24 - 2001/09/28	Gulbenkian advanced course on Functional Genomics (2001/09/24 - 2001/09/28)
1999/09/28 - 1999/09/28	Acção de formação: Curso de genética humana (1999/09/28 - 1999/09/28) Other (Other)
1998/11/12 - 1998/11/13	Seminário: Agentes biológicos: Segurança e saúde no ambiente de trabalho (1998/11/12 - 1998/11/13) Seminar (Member of the Organising Committee)

Event participation

	Activity description Type of event	Event name Institution / Organization
2005 - 2005	Laboratory Management Course Other	Laboratory Management Course EMBO Young Investigator Programme, Germany
2004 - 2004	Laboratory Management Course Other	Laboratory Management Course EMBO Young Investigator Programme, Germany
1987 - 1988	Molecular Microbiology Other	Molecular Microbiology Hospitais da Universidade de Coimbra, Portugal
1987 - 1988	Microbiology of Mineral and Surface Waters Other	Microbiology of Mineral and Surface Waters Universidade de Coimbra, Portugal
1986 - 1987	Advanced Separation Techniques Other	Advanced Separation Techniques Universidade de Coimbra, Portugal
1986 - 1987	Protein Separation and Phosphorylation Other	Protein Separation and Phosphorylation Universidade de Coimbra, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2018	Identification of novel regulators of protein synthesis fidelity using high content genetic screens Thesis Member	Joana Formigal Tavares (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017	Unravelling the roles of statistical proteomes in human cancer Supervisor	Mafalda Raquel da Conceição Santos (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017	Unravelling the celular networks that regulate proteotoxic stress Supervisor	Ana Sofia Paulo Varanda (PhD) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017	Provas de doutoramento em Biologia (Thesis) Main arguer	Joana Pinto Fernandes (PhD) Universidade de Aveiro, Portugal
2017	Provas de doutoramento em Biologia (Thesis) Main arguer	Joana Pinto Fernandes (PhD) Universidade de Aveiro, Portugal
2014/11/28	Identification and molecular characterization of boné-related microRNAs: functional implications (Thesis) Arguer	Lisete Machado e Silva (PhD) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2014/02/11	Identification and molecular characterization of bone-related microRNAs: functional implications (Thesis) Arguer	Ana Lúcia Marques Ramos (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014	Identification and molecular characterization of boné-related microRNAs: functional implications (Thesis) Arguer	Vânia Cristina Palma Roberto (PhD) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2014	Provas de mestrado em Biologia Molecular e Celular Thesis Member	André Figueiredo Rendeiro (Master) Universidade de Aveiro, Portugal
2013/09/30	Apoptosis and miRNAs in nin-alcoholic fatty liver disease pathogenesis (Thesis) Arguer	Duarte Miguel Sacramento Ferreira (PhD) Universidade de Coimbra Faculdade de Farmácia, Portugal
2013/07/17	Regulação de Eventos Exocitóticos pela via de sinalização do CAMP Thesis Member	Ana Isabel Costa Calejo (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2013/05	Role of Biotic interactions in generating and maintaining biodiversity (Thesis) Arguer	Migla Miskinyte Reis (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2013	Stress proteotóxico na estabilidade do genoma humano Supervisor	Inês Manuela Vale Santana (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2013	Phenotypic consequences of genome mistranslation in Candida albicans Supervisor	João Manuel Salvador Simões (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2013	Molecular genomics of a genetic code alteration Supervisor	Ana Rita Macedo Bezerra (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2013	Provas de doutoramento em Bioquímica (especialidade em Microbiologia) (Thesis) Arguer	Ana Sofia Ventura Cunha (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013	Provas de doutoramento em Bioquímica (especialidade em Microbiologia) (Thesis) Arguer	Ana Sofia Ventura Cunha (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/12/19	Evolution of the gene machinery and its applications to drug discovery President of the jury	Eva Maria Novoa Pardo (PhD) Universidade de Barcelona, Spain
2012/06/28	Exploring an uncommon host-parasite interaction to unveil the uniqueness of Perkinsus sp as a model organism (Thesis) Arguer	Ricardo Mário Bastos Leite (PhD) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2012/06/26	Provas de doutoramento em Bioquímica (especialidade de Microbiologia) (Thesis) Arguer	Ana Luísa Nabais Gomes Nobre (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/04/24	The role of mRNA translation on nonsense-mediated decay inhibition of transcripts carrying a short open reading frame (Thesis) Arguer	Isabel Cristina Ramos Peixeiro (PhD) Universidade de Lisboa Faculdade de Ciências, Portugal
2012/04/10	Skeletal muscle atrophy: the role of miRNAs (Thesis) Arguer	Ricardo José Ribeiro Soares (PhD) Universidade de Coimbra Faculdade de Medicina, Portugal
2012/04/03	New insight into translation during yeast programmed cell death (Thesis) Arguer	Maria Alexandra Oliveira da Silva (PhD) Universidade do Minho, Portugal
2012	Cianobactérias marinhas: avaliação do potencial anticancerígeno Thesis Member	Maria João Xavier Ribeiro (Master) Universidade de Aveiro Departamento de Química, Portugal
2012	A base genética da longevidade em Drosophila americana Thesis Member	Hélder Henrique Ribeiro Rocha (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2012	Quantificação de erros de incorporação em proteínas recombinantes Supervisor	Mohammad Zahangir Alam (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2012	Biodiversidade de estirpes de S. cerevisiae vínicas em Portugal Thesis Member	Sara Sofia Dinis de Sousa (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2012	Estudo do stress proteotóxico no peixe zebra Supervisor	Marisa Susete Reverendo Simões (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2012	The role of environmental stress on protein synthesis fidelity Supervisor	Ana Cristina Esteves Oliveira Gomes (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2012	Cellular responses to genome mistranslation Supervisor	Tatiana Lima de Vilhena Magalhães Costa (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2011/12/14	Integrating transcriptional termination with gene expression of polo Thesis Member	Telmo Filipe Antunes Henriques (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/12/09	Provas de doutoramento em Bioquímica (especialidade de Microbiologia) (Thesis) Arguer	Vítor Gonçalo Silva e Costa Mendes (PhD) Universidade de Coimbra, Portugal
2011/11/25	The role of ISC1P in signal transduction during oxidative stress and chronological aging in yeast (Thesis) Arguer	António Daniel Cardoso Barbosa (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/10/24	Provas de doutoramento em Biologia (especialidade de Genética Molecular) Thesis Member	Marco António Dias Coelho (PhD) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/06/01	Role of the transcriptional regulator FHL2: identification of fish target genes and regulatory mechanisms Thesis Member	Marta Isabel da Silva Rafael (PhD) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2011	Erros de tradução do mRNA em Candida albicans Supervisor	Diana Sofia Ortiga de Sousa (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	O Yap1 no stress causado pelo excesso de cobalto em S. cerevisiae Thesis Member	Soraia Cristina Marques Caetano (Master) Universidade de Aveiro Departamento de Química, Portugal
2011	Resistência a antifúngicos gerada por erros na tradução em levedura Supervisor	Ana Rita Dias Araújo (Master) Universidade de Aveiro Departamento de Química, Portugal
2011	Erros de tradução do mRNA em Saccharomyces cerevisiae Supervisor	Jorge Fernando Ferreira de Sousa Paulo (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Erros de tradução e estabilidade telomérica Supervisor	Filipa Isabel Serra e Silva (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Toxicidade de aminoácidos em peixe-zebra Supervisor	Pedro Emanuel Ferreira dos Reis Vieira (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Síntese proteica aberrante em células humanas HEK293FT Supervisor	Ana Sofia Paulo Varanda (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Susceptibilidade de Candida albicans à caspofungina e mutações de FKS1 Thesis Member	Joana Margarida Duarte Pedrosa (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Factores genéticos de risco para acidente vascular cerebral jovem Thesis Member	Ana Lúcia Francisco Correia (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Síntese de genes de novo Supervisor	Joana Pinto Fernandes (Master) Universidade de Aveiro Departamento de Química, Portugal
2011	Molecular reconstruction of a genetic code alteration Supervisor	Denisa Daud Mateus (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2011	Provas de mestrado em Biologia Celular e Molecular (Thesis) Arguer	Luís Pedro de Araújo Leitão (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010	Expressão de miRNAs no cérebro de Danio rerio exposto a etanol Supervisor	Violeta Silva Loureiro Alves Ferreira (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2010	Estudo molecular da epilepsia mioclonica progressiva Unverricht-Lundborg Thesis Member	Eugénia Maria Pinto (Master) Universidade de Aveiro Departamento de Biologia, Portugal
2010	Molecular study of cell degeneration and evolution induced by mRNA mistranslation Supervisor	João Cancela de Amorim Falcão Paredes (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2010	Sistema computacional para o estudo da estrutura primária e redesenho de genes Thesis Member	Miguel Monsanto Pinheiro (PhD) Universidade de Aveiro Departamento de Electrónica Telecomunicações e Informática, Portugal
2008/01/21	Provas de doutoramento em Biologia, especialidade de Microbiologia Thesis Member	Joana Cardoso da Costa (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008	Detecção de bactérias periodontais e análise de polimorfismos da IL1 Thesis Member	Marylin Pascoal dos Santos (Master) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2008	Molecular evolution of a genetic code alteration Supervisor	Ana Catarina Batista Gomes (PhD) Universidade de Aveiro Departamento de Biologia, Portugal
2008	Provas de mestrado em Biologia Molecular e Celular Thesis Member	Cidália Maria Teixiera Gomes (Master) Universidade de Aveiro, Portugal
2008	Provas de doutoramento no ramo e especialidade de Biologia Thesis Member	José Manuel Café Inácio (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2007/06/04	Provas de doutoramento em Ciências da Saúde, área de conhecimento de Ciências Biológicas e Biomédicas (Thesis) Arguer	Agostinho João Ramalho de Almeida (PhD) Universidade do Minho, Portugal
2007/01	Bioinformatics Studies on the Complexity of splicing and gene expression Thesis Member	Nuno Luís Barbosa Morais (PhD) Universidade de Lisboa Faculdade de Medicina, Portugal
2007	Quitosano para vectorização de genes: do tráfego intracelular à expressão genética Thesis Member	Liliana Raquel Fernandes Pires (Master) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2007	Provas de doutoramento em Biologia Supervisor	Pedro Daniel Coelho dos Santos Beltrão (PhD) Universidade de Aveiro, Portugal
2006/11/03	Provas de doutoramento em Bioquímica, na especialidade de Microbiologia (Thesis) Arguer	Ana Paula Kuan Yon Chung (PhD) Hospitais da Universidade de Coimbra, Portugal
2006	Provas de doutoramento em Biologia Thesis Member	Artur Jorge da Costa Peixoto Alves (PhD) Universidade de Aveiro, Portugal
2006	Provas de doutoramento em Biologia, especialidade de Biologia Molecular Thesis Member	Luís Tiago Ferreira Romero Magalhães (PhD) Hospitais da Universidade de Coimbra, Portugal
2006	Provas de doutoramento em Bioquímica, especialidade de Microbiologia (Thesis) Arguer	André Guimarães Lemos Antunes (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2005/04/22	Ecm33p, una proteína com anclaje a GPI, está implicada en los processos de formación de la pared celular, morfogénesis y virulência de Candida albicans (Thesis) Arguer	Raquel Martínez López (PhD) Universidad Complutense de Madrid Facultad de Farmacia, Spain
2005	Provas de doutoramento em Biologia (ramo e especialidade) Thesis Member	Sara Cristina de Almeida Pinto Garcia (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2004/02/03	Pathways for the synthesis of mannosylglycerate in prokaryotes: genes enzymes and evolutionary implications (Thesis) Arguer	Nuno Miguel da Silva Empadinhas (PhD) Universidade de Coimbra, Portugal
2004	Analysis of the G checkpoint during spore development in Bacillus subtilis Thesis Member	Mónica Paula Fernandes Serrano Miranda (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2003/07/15	Expressão da proteína E6 do HPV-16 em Saccharomyces cerevisiae Thesis Member	Ana Cristina Simões de Oliveira (Master) Universidade de Aveiro, Portugal
2002/09/30	Monocarboxylic Acid Transport in Saccharomyces cerevisiae: molecular characterization of JEN1 expression (Thesis) Arguer	Raquel Gláucia Varzielas Pego de Andrade (PhD) Universidade do Minho, Portugal
2002/02/19	Transporte e utilização de ácidos dicarboxílicos nas leveduras Kluyveromyces sp. e Saccharomyces cerevisiae: Uma abordagem fisiológica, bioquímica e genética (Thesis) Arguer	Odília dos Anjos Pimenta Morais de Queirós (PhD) Universidade do Minho, Portugal
2001/09/11	Metabolic strategies to reroute carbon fluxes in Lactococcus lactis (Thesis) Arguer	Ana Rute Ramos Neves (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
1999/12/21	Evidências da multifuncionalidade da proteína p37 de Kluvyveromyces marxianus (Thesis) Arguer	Roxana Esmeriz Falcão Moreira (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1998/12/16	Obtenção e caracterização de mutantes da NADH: ubiquinona oxidorredutase (Thesis) Arguer	Paulo Alexandre Marreiros Caseiro Alves (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1998/12/09	Posttranscriptional control of the Saccharomyces cerevisiae stress-related transcription factor genes YAP1 and YAP2 (Thesis) Arguer	Cristina Paula Gameiro Vilela (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Association member

	Society Organization name	Role
2014 - 2018	Sociedade Portuguesa de Genética	Membro da Direção

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2017/04	Departamento de Ciências Médicas da Universidade de Aveiro : A sala de aula é hoje um espaço público	Revista Perspectivas - distribuída pelo Jornal Público
2016/05	Departamento de Ciências Médicas da Universidade de Aveiro : Criar conhecimento em prol da saúde dos portugueses	Revista Exlibris – distribuída pelo Jornal Público
2014/12/11	Projecto 20+20	Jornal Expresso
2014/01/02	Recoding Life – Rewriting the genetic code can lead to a better understanding of how living cells work, and spawn new biotechnological applications.	The Scientist
2003	Renegade code	New Scientist
2002/09	A biologia computacional na análise dos genomas	Folha Informatica da UA
2001/04	Genómica funcional em Aveiro	Boletim de Biotecnologia
1999/12/18	Candida sob investigação	Jornal Expresso
1999/12/14	Investigadores estudam fungo responsável por várias infecções	Diário das Beiras
1999/12/13	Aveiro: Cientistas estudam fungo responsável por infecções	Agência LUSA
1998/06/20	Code Breakers: breaking the genetic code makes a yeast healthier than ever	New Scientist
1996/07/04	Research Fellow Profiles	Bioscience news, Research School of Biosciences (University of Kent Printing Unit)
1995/07/02	The genetic code is not universal	Bioscience news, Research School of Biosciences (University of Kent Printing Unit)

Interview (tv / radio show)

	Program	Topic
2018 - 2018	Programa 90 segundo de Ciência da rádio Antena-1	Projecto pAGE : Protein aggregation Across the LifeSpan

Other jury / evaluation

	Activity description	Institution / Organization
2018/04 - 2018/04	Presidente de júri no concurso público n.º 33 – aCAL/BiMED – 04/18, tendo em vista a aquisição de equipamentos de computação no âmbito do projeto GenomePT	Universidade de Aveiro Instituto de Biomedicina, Portugal
2018/04 - 2018/04	Presidente de júri no concurso público n.º 36 – aCAL/dcm – 04/18, tendo em vista a aquisição de equipamento de microscopia confocal e respetivos acessórios	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 - 2018	Presidente de júri no CDL-CTTRI-144-ARH/2018 - Aviso n.º 19157/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, para o exercício de atividades de investigação científica na área científica de Ciências Biomédicas
2018 - 2018	Presidente de júri no CDL-CTTRI-149-ARH/2018 – Aviso n.º 16628/2018 - Declaração de Retificação n.º 859/2018 – Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, para o exercício de atividades de investigação científica nas áreas científicas de Ciências Biomédicas, Biologia ou afins, no âmbito do projeto CANCYL – POCI-01-0145-FEDER-031849, suportado pelos orçamentos do Programa Operacional POCI, na sua componente FEDER, e da Fundação para a Ciência e a Tecnologia, na sua componente de Orçamento de Estado
2018 - 2018	Presidente de júri no CDL-CTTRI-89-ARH/2018 - REF.169-89-ARH/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, na(s) área(s) científica(s) de Ciências Biomédicas, no âmbito da Bolsa BPD/UI98/3304/2016
2018 - 2018	Presidente de júri no CDL-CTTRI-153-ARH/2018 - Aviso n.º 17929/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, para o exercício de atividades de investigação científica na área científica da Matemática
2018 - 2018	Presidente de júri no CDL-CTTRI-88-ARH/2018 - REF.030-88-ARH/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, na(s) área(s) científica(s) de Ciências Biomédicas, no âmbito da Bolsa SFRH/BPD/111148/2015
2018 - 2018	Presidente de júri no CDL-CTTRI-88-ARH/2018 - REF.029-88-ARH/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, na(s) área(s) científica(s) de Ciências Biomédicas, no âmbito da Bolsa SFRH/BPD/77619/2011
2018 - 2018	Presidente de júri no CDL-CTTRI-88-ARH/2018 - REF.028-88-ARH/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, na(s) área(s) científica(s) de Ciências Biomédicas, no âmbito da Bolsa SFRH/BPD/96741/2013
2018 - 2018	Presidente de júri no CDL-CTTRI-88-ARH/2018 - REF.027-88-ARH/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, na(s) área(s) científica(s) de Ciências Biomédicas, no âmbito da Bolsa SFRH/BPD/77528/2011
2018 - 2018	Presidente de júri no CDL-CTTRI-89-ARH/2018 – REF.-169 - 89-ARH/2018 - Concurso de âmbito internacional para recrutamento de 1 (um) lugar de Doutorado, na(s) área(s) científica(s) de Ciências Biomédicas, no âmbito do Bolsa (BPD/UI98/3304/2016)
2018 - 2018	Presidente de júri no Processo de Seleção e Recrutamento – Ref.ª CND-CTTRC-165-ARH/2018 – 1 lugar contratualmente equiparado à categoria de Técnico Superior, para ocupar o posto de trabalho de Técnico de Laboratório, nos termos do Código do Trabalho
2017/09 - 2017/09	Presidente de júri no concurso público n.º 169 – aCAL/iBiMED – 09/17, tendo em vista a aquisição de equipamentos científicos no âmbito do projeto GenomePT	Universidade de Aveiro Instituto de Biomedicina, Portugal
2017/07 - 2017/07	Presidente de júri no ajuste Direto n.º 110 - aCP/dcm - 07/17, tendo em vista a aquisição de Mobiliário de Laboratório, para equipar Laboratórios de Aulas Práticas	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/07 - 2017/07	Presidente de júri no ajuste Direto n.º 112 - aCP/dcm - 07/17, tendo em vista a aquisição de equipamentos para os laboratórios de aulas práticas	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/07 - 2017/07	Presidente de júri no ajuste Direto n.º 108 - aCAL/iBiMED - 07/17, tendo em vista a aquisição de serviços especializados na preparação e revisão de candidaturas a projetos regionais, nacionais e europeus	Universidade de Aveiro Instituto de Biomedicina, Portugal
2017 - 2017	Membro de júri no CD-CTTI-51-ARH/2017 - Concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, para a área disciplinar de Ciências Biomédicas (CBM), subárea de Farmacologia (CBM—FARM), em regime de contrato de trabalho por tempo indeterminado, ao abrigo do Código do Trabalho e do Regulamento sobre Regime das Carreiras Próprias do Pessoal Docente em Regime de Direito Privado da Universidade de Aveiro e Respetiva Contratação (Regulamento n.º 384/2014, de 26 de agosto)
2017 - 2017	Membro de júri no CD-CTTI-52-ARH/2017 - Concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, para a área disciplinar de Ciências Biomédicas (CBM), subárea de Imunologia (CBM—IMN), em regime de contrato de trabalho por tempo indeterminado, ao abrigo do Código do Trabalho e do Regulamento sobre Regime das Carreiras Próprias do Pessoal Docente em Regime de Direito Privado da Universidade de Aveiro e Respetiva Contratação (Regulamento n.º 384/2014, de 26 de agosto)
2017 - 2017	Membro de júri no CD-CTTI-53-ARH/2017 - Concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, para a área disciplinar de Ciências Biomédicas (CBM), subárea de Biomedicina do Envelhecimento (CBM—ENV), em regime de contrato de trabalho por tempo indeterminado, ao abrigo do Código do Trabalho e do Regulamento sobre Regime das Carreiras Próprias do Pessoal Docente em Regime de Direito Privado da Universidade de Aveiro e Respetiva Contratação (Regulamento n.º 384/2014, de 26 de agosto)
2017 - 2017	Membro de júri no CD-CTTI-54-ARH/2017- Concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, para a área disciplinar de Ciências Biomédicas (CBM), subárea de Biomedicina Molecular (CBM—BMD), em regime de contrato de trabalho por tempo indeterminado, ao abrigo do Código do Trabalho e do Regulamento sobre Regime das Carreiras Próprias do Pessoal Docente em Regime de Direito Privado da Universidade de Aveiro e Respetiva Contratação (Regulamento n.º 384/2014, de 26 de agosto)
2016/11 - 2016/11	Presidente de júri no ajuste direto n.º 152 - aCAL/iBiMED- 11/16, tendo em vista a aquisição de mobiliário para equipar as salas de laboratório	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016/04 - 2016/04	Presidente de júri na concurso público n.º 30 - aCAL/iBIMED – 04/16, tendo em vista a aquisição de equipamentos de laboratório	Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016 - 2016	Membro de júri no concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, na área disciplinar de Ciências Biomédicas, subárea de Epidemiologia. Diário da República, 2.ª série — N.º 235 — 9 de dezembro de 2016.Edital 149/2016
2016 - 2016	Membro de júri no concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, na área disciplinar de Ciências Biomédicas, subárea de Neurociências. Diário da República, 2.ª série — N.º 235 — 9 de dezembro de 2016.Edital 148/2016
2016 - 2016	Concurso documental, de âmbito internacional, para recrutamento de 1 (um) posto de trabalho de Professor Auxiliar, na área disciplinar de Ciências Biomédicas, subárea de Biomedicina Molecular. Diário da República, 2.ª série — N.º 235 — 9 de dezembro de 2016.Edital 1050/2016
2015/08 - 2015/08	Presidente de júri na concurso público n.º 114 aCAL/sacs – 08/15, tendo em vista a aquisição de sistemas de purificação de água para obtenção de água purificada de qualidade	Universidade de Aveiro Instituto de Biomedicina, Portugal
2015 - 2015	Membro de júri no concurso documental para recrutamento de um posto de trabalho de Professor Auxiliar para a área disciplinar de Biologia Molecular e Microbiologia no âmbito do Departamento de Ciências da Vida da Faculdade de Ciências e Tecnologia (edital nº 855/2014, Universidade Nova de Lisboa)
2014 - 2014	Membro de júri no concurso documental, de âmbito internacional, para recrutamento de um posto de trabalho de Professor Auxiliar na área disciplinar de Biologia, da Escola de Ciências (edital nº 621/2013), Universidade do Minho
2013/06/30 - 2013/06/30	Presidente de júri na contratação de bolseiro. Bolsa de investigação (BI) no âmbito do projeto FCT: PTDC/BIA-MIC/099826/2008. Candidatura aprovada: João Manuel Salvador Simões	Universidade de Aveiro Departamento de Biologia, Portugal
2013/06/24 - 2013/06/24	Presidente de júri na contratação de bolseiro. Bolsa de investigação (BI) no âmbito do projeto FCT: FCT-ANR/IMI-MIC/0041/2012. Candidatura aprovada: Edgar Lopes	Universidade de Aveiro Departamento de Biologia, Portugal
2013/05/24 - 2013/05/24	Presidente de júri na contratação de bolseiro. Bolsa de investigação (BI) no âmbito do projeto FCT: PTDC/SAU-GMG/098850/2008. Candidatura aprovada: Marisa Reverendo Simões	Universidade de Aveiro Departamento de Biologia, Portugal
2013/05/21 - 2013/05/21	Presidente de júri na contratação de bolseiro. Bolsa de investigação (BI) no âmbito do projeto FCT: FCT-ANR/IMI-MIC/0041/2012. Candidatura aprovada: Ana Rita Macedo Bezerra	Universidade de Aveiro Departamento de Biologia, Portugal
2012/09 - 2012/09	Presidente de júri em concurso para aquisição de bens e serviços. Concurso público (nº 32 – aCAL/CESAM – 09/12), Aquisição e instalação de um sequenciador de DNA/genomas de última geração	Universidade de Aveiro, Portugal
2012/09 - 2012/09	Presidente de júri em concurso para aquisição de bens e serviços. Concurso público (nº 33 – aCAL/CESAM – 09/12), Aquisição e instalação de um citómetro de fluxo	Universidade de Aveiro, Portugal
2012/03/23 - 2012/03/23	Membro do júri em concurso para contratação de pessoal (2011). Lugar de Professor Auxiliar para a área disciplinar de Genética Molecular / Genética Molecular de Eucariontes, vertente Humana da Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa. Candidatura aprovada: Doutora Maria Alexandra Núncio de Carvalho Ramos Fernandes, Professora Associada da Universidade Lusófona de Humanidades e Tecnologia
2012/02/01 - 2012/02/01	Presidente de júri na contratação de bolseiro. Bolsa de investigação (BI) no âmbito do projeto FCT: PTDC/BIA-MIC/099826/2008. Candidatura aprovada: João Manuel Salvador Simões	Universidade de Aveiro Departamento de Biologia, Portugal
2012/02/01 - 2012/02/01	Presidente de júri na contratação de bolseiro. Bolsa de investigação (BI) no âmbito do projeto FCT: PTDC/BIA-MIC/098850/2008. Candidatura aprovada: Ana Rita Macedo Bezerra	Universidade de Aveiro Departamento de Biologia, Portugal
2012 - 2012	Membro de júri em concurso internacional para aquisição de bens e serviços. Ajuste directo (nº 99/2012), Aquisição e instalação de 2 termocicladores e 1 PCR tempo real	Universidade de Aveiro, Portugal
2011 - 2011	Presidente de júri em concurso para aquisição de bens e serviços. Ajuste directo (nº 50/2011), Aquisição e instalação de um microscópio confocal com capacidade de leitura automática de arrays de células e single cell imaging	Universidade de Aveiro, Portugal
2011 - 2011	Membro de júri em concurso para aquisição de bens e serviços. Ajuste directo (nº 48/2011), Aquisição e instalação de um módulo de leitura de arrays de muito alta densidade para acoplar ao scanner Agilent, Universidade de Aveiro	Universidade de Aveiro, Portugal
2011 - 2011	Membro de júri em concurso para contratação de pessoal. Lugar de Personal Chair, Universidade de Aberdeen. Dr Ian Stansfield
2011 - 2011	Membro de júri em concurso para contratação de pessoal. Lugar de Professor Auxiliar para a área de Ciências da Vida, área disciplinar de Biologia Celular e Molecular (Microbiologia) da Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa

Distinctions

Award

2011	Prémio Prof. Doutor Amândio Sampaio Tavares
2009	Prémio Young Investigator Award
2005	Prémio Young Investigator Award
2003	2º Prémio Universidades da Microsoft Microsoft Portugal, Portugal
2000	Prémio Gulbenkian de estímulo à investigação científica Fundação Calouste Gulbenkian, Portugal