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Simão P. B. Teixeira graduated in Bioengineering - Molecular Biotechnology at the University of Porto in 2017. In January 2024, he obtained his Doctor (PhD) degree in Tissue Engineering, Regenerative Medicine and Stem Cells awarded by the University of Minho with the maximum grade, with the thesis entitled "Molecular Imprinting Technologies for Growth Factor Sequestration and Control of Stem Cell Fate in Tendon Regeneration". The PhD project was conducted at 3B's Research Group, I3Bs - University of Minho, under the supervision of Professor Manuela E. Gomes and Dr. Rui M. A. Domingues. During this time, he had the opportunity to be a visiting researcher at University College London (Eastman Dental Institute), ETH Zurich and University of Zurich, some of the most prestigious European universities. He has been involved in several international projects, like the ERC Consolidator Grant MagTendon (772817) or Twinning project Achilles (810850), awarded to Prof. Manuela E. Gomes, as well as national ones such as SmarTendon (PTDC/NAN-MAT/30595/2017) and Wi-Pi (doi.org/10.54499/2022.05526.PTDC), awarded by FCT to Dr. Rui M. A. Domingues in international collaborations. Simão served as student representative of I3Bs in the University of Minho Doctoral College for 2 years. He also participated in the organization of 3 conferences and 1 workshop under the Achilles project, as well as the 31st Annual Meeting of the European Orthopaedic Research Society (EORS 2023) in Porto, Portugal. His early career has thus far yielded 5 published papers (4 as first author) in high impact (Q1, top 10%) journals like Advanced Functional Materials or Science Advances, with a current total of over 180 citations (h-index = 4), 1 patent application, 7 oral presentations at international conferences, including awards for Best Rapid-Fire Presentation (2nd Achilles Conference, 2019), EORS 2024 New Investigator Special Award (top 3 finalist) and ON/EORS Orthoregeneration Award 2024 (best paper on orthoregeneration), along with 6 poster presentations.
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Identification

Personal identification

Full name
Simão Pedro Barbosa Teixeira

Citation names

  • Teixeira, Simão
  • Teixeira, Simão P. B.

Author identifiers

Ciência ID
E313-09DA-1166
ORCID iD
0000-0003-2764-4319
Google Scholar ID
TjdgbK4AAAAJ&hl
Researcher Id
AAA-6002-2022
Scopus Author Id
57215717709

Email addresses

  • simao.teixeira@i3bs.uminho.pt (Professional)

Telephones

Fax
  • 253510909 (Professional)
Telephone
  • 253510948 (Professional)
  • 253510900 (Professional)

Addresses

  • I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho. Avepark - Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017, Barco, Guimarães, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Advanced (C1) Proficiency (C2) Upper intermediate (B2) Advanced (C1)
Japanese Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2018/09 - 2024/01/10
Concluded
 Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento)
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
"Molecular Imprinting Technologies for Growth Factor Sequestration and Control of Stem Cell Fate in Tendon Regeneration" (THESIS/DISSERTATION)
 Muito bom
2012/09 - 2017/10
Concluded
 Bioengenharia (Mestrado)
Major in Área de especialização: Biotecnologia Molecular
Universidade do Porto Faculdade de Engenharia, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Trimethyl-Chitosan-based Polyplexes for Neurotrophin Mimicking in Brain Ischaemia" (THESIS/DISSERTATION)
 17 valores
Affiliation

Science

Category
Host institution 		Employer
2024/03/01 - Current Contracted Researcher (Research) Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
Biomaterials Biodegradables and Biomimetics, Portugal
2022/09/01 - 2022/12/20 Visiting Researcher (Research) Eidgenössische Technische Hochschule Zürich, Switzerland
Universitätsklinik Balgrist, Switzerland
2022/09/01 - 2022/12/20 Visiting Researcher (Research) Universität Zürich, Switzerland
Universitätsklinik Balgrist, Switzerland
2020/03/09 - 2020/03/30 Visiting Researcher (Research) University College London Eastman Dental Institute, United Kingdom

Others

Category
Host institution 		Employer
2018/09/01 - 2024/01/10 Estudante de Doutoramento/PhD student Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
Biomaterials Biodegradables and Biomimetics, Portugal
2017/02/06 - 2017/10/13 Estudante de Mestrado/MSc student Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/02/15 - 2016/07/30 Estagiário/Trainee (Erasmus+) Max Bergmann Center of Biomaterials Dresden, Germany
Technische Universität Dresden, Germany
(...)
Projects

Grant

Designation Funders
2018/09 - 2023/04/05 Doctoral Program in Advanced Therapies for Health
PD/BD/143039/2018
PD/00169/2013
COVID/BD/153025/2022
PhD Student Fellow
Biomaterials Biodegradables and Biomimetics, Portugal

Laboratório Associado ICVS 3B's, Portugal
Fundação para a Ciência e a Tecnologia

European Social Fund
Concluded

Contract

Designation Funders
2023/03/01 - 2025/08/31 Wi-Pi - Plataforma wireless de atuadores abióticos para estudar a mecanobiologia dos receptores PIEZO
2022.05526.PTDC
10.54499/2022.05526.PTDC
Post-doc
Universidade do Minho, Portugal

Biomaterials Biodegradables and Biomimetics, Portugal

Universidade de Santiago de Compostela Facultade de Física, Spain
Fundação para a Ciência e a Tecnologia
Ongoing
2018/09/01 - 2024/05/15 MagTendon - Magnetically Assisted Tissue Engineering Technologies for Tendon Regeneration
772817
10.3030/772817
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
 European Commission
Ongoing
2022/11/02 - 2024/04/30 BioCHIPs - Innovative microfluidics-based platform for biofabrication of tissue-/organs-on-a-chip
101069302
10.3030/101069302
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
 European Research Council
Concluded
2018/09/01 - 2023/07/05 TERM RES-Hub .: Infraestrutura em Engenharia de Tecidos e Medicina Regenerativa
NORTE-01-0145-FEDER-022190
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
 Fundação para a Ciência e a Tecnologia

Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2018/10/01 - 2022/06/30 ACHILLES - Overcoming specific weaknesses in tendon biology to design advanced regenerative therapies
810850
10.3030/810850
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
 European Commission
Concluded
2018/07/01 - 2021/06/30 SmarTendon - Growth Factors Sequestering Biomaterials to Engineer Living Tendon Grafts based on Molecularly Imprinted Nanoparticles
PTDC/NAN-MAT/30595/2017
PhD Student Fellow
Universidade do Minho, Portugal

Biomaterials Biodegradables and Biomimetics, Portugal

Laboratório Associado ICVS 3B's, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/09/01 - 2020/10/29 "Accelerating tissue engineering and personalized medicine discoveries by the integration of key enabling nanotechnologies, marine-derived biomaterials and stem cells”
NORTE-01-0145-FEDER-000021
PhD Student Fellow
Biomaterials Biodegradables and Biomimetics, Portugal

Laboratório Associado ICVS 3B's, Portugal
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2019/01/01 - 2019/12/31 Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
LA/P/0070/2020
10.54499/LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/09/01 - 2019/12/31 Implementation of The Discoveries Centre for Regenerative and Precision Medicine, a new Centre of Excellence in Portugal
739572
10.3030/739572
Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
 European Commission
Concluded
Outputs

Publications

Conference paper
  1. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Bioinspired hydrogels promote tenogenic stem cell commitment by synergistic control over topographical cues and growth factor signaling". Paper presented in Tissue Engineering and Regenerative Medicine International Society European Chapter Conference (TERMIS-EU) 2023, Manchester, 2023.
    Published • 10.1089/ten.tea.2023.29043.abstract
  2. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Gomes, ME; Domingues, Rui M. A.. "Directing Stem Cell Commitment in 3D Bioinspired Hydrogels by Growth Factor Sequestration using Molecularly Imprinted Nanoparticles". Paper presented in TERMIS-EU 2022, Krakow, 2022.
    Published • 10.1089/ten.tea.2023.29046.abstracts
  3. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Bioinspired Composite Hydrogels Direct Stem Cell Fate Toward Tenogenesis by Synergistically Modulating Growth Factor Signalling and Local Microtopography". Paper presented in Final Achilles Conference, Guimarães, 2022.
  4. Teixeira, Simão P. B.; Domingues, Rui M. A.; Babo, Pedro S; Margarida S. Miranda; Manuela E. Gomes; Peppas, Nicholas A.; Reis, Rui L.. "Directing stem cell phenotype commitment by sequestering transforming growth factor-ß3 with epitope imprinted nanoparticles". Paper presented in 31st Conference of the European Society for Biomaterials (ESB), Porto, 2021.
Conference poster
  1. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Bioinspired Hydrogels Promote Tenogenic Stem Cell Commitment by Synergistic Control over Topographical Cues and Growth Factor Signaling". Paper presented in HEALTH-UNORTE Conference, 2023.
  2. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "3D Bioinspired Hydrogels with Molecularly Imprinted Nanoparticles Sequester Endogenous Growth Factors and Synergistically Direct Stem Cell Fate Commitment". Paper presented in ESB 2022 - 32nd Annual Conference of the European Society for Biomaterials, 2022.
  3. Teixeira, Simão P. B.; Pardo, Alberto; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Directing stem cell commitment in 3D bioinspired hydrogels by growth factor sequestration using molecularly imprinted nanoparticles". Paper presented in Third Achilles Workshop, 2021.
  4. Teixeira, Simão; Reis, Rui L.; Domingues, Rui M. A.; Gomes, Manuela E.. "Directing stem cell commitment toward tenogenesis by functionalizing tendon-mimetic grafts with epitope imprinted nanoparticles". Paper presented in Second Achilles Conference, 2019.
  5. Teixeira, Simão P. B.; Reis, Rui L.; Domingues, Rui M. A.; Manuela E. Gomes. "Directing stem cell commitment toward tenogenesis by functionalizing tendon-mimetic grafts with epitope imprinted nanoparticles". Paper presented in First Discoveries Forum on Regenerative and Precision Medicine, 2019.
  6. Teixeira, Simão P. B.; Reis, Rui L.; Domingues, Rui M. A.; Manuela E. Gomes. "Epitope-imprinted nanoparticles for TGF-ß3 sequestration and control of stem cell fate in tendon regeneration". Paper presented in First Achilles Conference, 2019.
Journal article
  1. Teixeira, S. P. B.; Pardo, A.; Taboada, P.; Wolleb, M.; Snedeker, J.; Reis, R. L.; Gomes, M. M. E.; Domingues, R. M. A.. "TAILOR-MADE NANOSWITCHES FOR TARGETED MODULATION OF PIEZO1 MECHANOSENSING INFLUENCE STEM CELL FATE". Orthopaedic Proceedings 106-B SUPP_18 (2024): 46-46. http://dx.doi.org/10.1302/1358-992x.2024.18.046.
    Published • 10.1302/1358-992x.2024.18.046
  2. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell-Scale Biophysical Cues in Bioengineered Constructs". Advanced Functional Materials (2024): 2312961. https://onlinelibrary.wiley.com/doi/10.1002/adfm.202312961.
    Open access • Published • 10.1002/adfm.202312961
  3. Teixeira, S.P.B.; Pardo, A.; Bakht, S.M.; Gomez-Florit, M.; Reis, R.L.; Gomes, M.E.; Domingues, R.M.A.. "3D BIOMIMETIC CONSTRUCTS STEER STEM CELL COMMITMENT BY SYNERGISTIC MODULATION OF BIOPHYSICAL CUES AND GROWTH FACTOR SIGNALLING". Orthopaedic Proceedings 106-B SUPP_1 (2024): 13-13. http://dx.doi.org/10.1302/1358-992x.2024.1.013.
    Published • 10.1302/1358-992x.2024.1.013
  4. Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Rial, Ramón; Monteiro, Rosa F.; Teixeira, Simão P. B.; Taboada, Pablo; et al. "Magnetically-Assisted 3D Bioprinting of Anisotropic Tissue-Mimetic Constructs". Advanced Functional Materials 32 50 (2022): 2208940. http://dx.doi.org/10.1002/adfm.202208940.
    Open access • Published • 10.1002/adfm.202208940
  5. Teixeira, Simão P. B.; Reis, Rui L.; Peppas, Nicholas A.; Manuela E. Gomes; Domingues, Rui M. A.. "Epitope-imprinted polymers: Design principles of synthetic binding partners for natural biomacromolecules". Science Advances 7 44 (2021): eabi9884. http://dx.doi.org/10.1126/sciadv.abi9884.
    Open access • Published • 10.1126/sciadv.abi9884
  6. Teixeira, Simão P. B.; Domingues, Rui M. A.; Babo, Pedro S; Berdecka, Dominika; Miranda, Margarida S.; Manuela E. Gomes; Peppas, Nicholas A.; Reis, Rui L.. "Epitope-Imprinted Nanoparticles as Transforming Growth Factor-ß3 Sequestering Ligands to Modulate Stem Cell Fate". Advanced Functional Materials 31 4 (2020): 2003934. http://dx.doi.org/10.1002/adfm.202003934.
    Published • 10.1002/adfm.202003934
  7. Teixeira, Simão P. B.; Domingues, Rui M. A.; Shevchuk, Mariya; Manuela E. Gomes; Peppas, Nicholas A.; Reis, Rui L.. "Biomaterials for Sequestration of Growth Factors and Modulation of Cell Behavior". Advanced Functional Materials 30 44 (2020): 1909011. http://dx.doi.org/10.1002/adfm.201909011.
    Published • 10.1002/adfm.201909011
Thesis / Dissertation
  1. "Molecular imprinting technologies for growth factor sequestration and control of stem cell fate in tendon regeneration". PhD, Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, 2024. https://hdl.handle.net/1822/88237.
  2. "Trimethyl-Chitosan-based Polyplexes for Neurotrophin Mimicking in Brain Ischaemia". Master, Universidade do Porto Faculdade de Engenharia, 2017. https://repositorio-aberto.up.pt/handle/10216/108361.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/09/19 TAILOR-MADE NANOSWITCHES FOR TARGETED MODULATION OF PIEZO1 MECHANOSENSING INFLUENCE STEM CELL FATE EORS 2024 - 32nd Annual Meeting of the European Orthopaedic Research Society
Aalborg University, Denmark (Aalborg, Denmark)
2023/09 3D Biomimetic Constructs Steer Stem Cell Commitment by Synergistic Modulation of Biophysical Cues and Growth Factor Signaling EORS 2023 - 31st Annual Meeting of the European Orthopaedic Research Society
3B's Research Group (Porto, Portugal)
2022/06/29 Directing Stem Cell Commitment in 3D Bioinspired Hydrogels by Growth Factor Sequestration using Molecularly Imprinted Nanoparticles TERMIS European Chapter Conference 2022
Tissue Engineering and Regenerative Medicine International Society (Krakow, Poland)
2022/05 Bioinspired Composite Hydrogels Direct Stem Cell Fate Toward Tenogenesis by Synergistically Modulating Growth Factor Signalling and Local Microtopography Final Achilles Conference
3B's Research Group (Guimaraes, Portugal)
2021/09/09 Directing stem cell phenotype commitment by sequestering transforming growth factor-ß3 with epitope imprinted nanoparticles 31st Conference of the European Society for Biomaterials (ESB)
Institute for Research and Innovation in Health (i3S) and INEB – Instituto de Engenharia Biomédica, University of Porto, Portugal (Porto, Portugal)
2019/11/05 Directing stem cell commitment toward tenogenesis by functionalizing tendon-mimetic grafts with epitope imprinted nanoparticles Second Achilles Conference
3B's Research Group (Braga, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/09/27 - 2023/09/29 EORS 2023 - 31st Annual Meeting of the European Orthopaedic Research Society Local organizing committee (2023/09/27 - 2023/09/29)
Meeting (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2022/05/25 - 2022/05/27 Final Achilles Conference - "Tendon Regeneration: a throwback to the lessons learned and prospects to the future" Local organizing committee (2022/05/25 - 2022/05/27)
Conference (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2021/10/25 - 2021/10/27 Third Achilles Workshop - "Gene & Cell Therapy and Clinical Applications" Local organizing committee (2021/10/25 - 2021/10/27)
Workshop (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2019/11/04 - 2019/11/05 Second Achilles Conference - "Tendon Biophysical Environment" Local organizing committee (2019/11/04 - 2019/11/05)
Conference (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2019/07/08 - 2019/07/10 First Achilles Conference - "Molecular and Biological Mechanisms of Tendon Homeostasis and Repair" Local organizing committee (2019/07/08 - 2019/07/10)
Conference (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal

Committee member

Activity description
Role 		Institution / Organization
2020/03/01 - 2022/02/28 Representante dos estudantes de doutoramento do I3Bs na Comissão Coordenadora do Colégio Doutoral da Universidade do Minho
Member
 Universidade do Minho, Portugal
Distinctions

Award

2024 EORS 2024 New Investigator Special Award (Top 3 Finalist)
European Orthopaedic Research Society, Germany
2024 ON/EORS Orthoregeneration Award 2024
ON Foundation, Switzerland

European Orthopaedic Research Society, Germany
2019 Best Rapid Fire Presentation - Second Achilles Conference
Biomaterials Biodegradables and Biomimetics, Portugal

Laboratório Associado ICVS 3B's, Portugal

Universidade do Minho, Portugal

EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation, Belgium

Fundação para a Ciência e a Tecnologia, Portugal