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Simão P. B. Teixeira graduated in Bioengineering - Molecular Biotechnology at the University of Porto in 2017. In January 2024, he obtained his Doctor (PhD) degree in Tissue Engineering, Regenerative Medicine and Stem Cells awarded by the University of Minho with the maximum grade, with the thesis entitled ¿Molecular Imprinting Technologies for Growth Factor Sequestration and Control of Stem Cell Fate in Tendon Regeneration¿. The PhD project was conducted at 3B¿s Research Group, I3Bs ¿ University of Minho, under the supervision of Professor Manuela E. Gomes and Dr. Rui M. A. Domingues. During this time, he had the opportunity to be a visiting researcher at University College London (Eastman Dental Institute) and ETH Zurich (Institute for Biomechanics), two of the most prestigious European universities. In the latter, he worked at Balgrist Campus under Prof. Jess G. Snedeker, in a collaborative project focusing on tendon mechanotransduction. He has been involved in several international projects, like the ERC Consolidator Grant MagTendon or Twinning project Achilles, awarded to Prof. Manuela E. Gomes, as well as national ones such as SmarTendon and Wi-Pi, awarded to Dr. Rui M. A. Domingues in international collaborations. Simão served as student representative of I3Bs in the University of Minho Doctoral College for 2 years. He also participated in the organization of 3 national conferences and 1 workshop, under the Achilles project, as well as the 31st Annual Meeting of the European Orthopaedic Research Society (EORS 2023) in Porto, Portugal. His early career has thus far yielded 5 published papers (4 as first author) in high impact journals like Advanced Functional Materials or Science Advances, with a current total of 135 citations, with another in submission, 1 patent application, 4 oral presentations at international conferences and 2 at national conferences, including an award for Best Rapid-Fire Presentation (2nd Achilles Conference, 2019), along with 6 poster presentations.
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Identification

Personal identification

Full name
Simão Pedro Barbosa Teixeira

Citation names

  • Teixeira, Simão
  • Teixeira, Simão P. B.

Author identifiers

Ciência ID
E313-09DA-1166
ORCID iD
0000-0003-2764-4319
Google Scholar ID
TjdgbK4AAAAJ&hl
Researcher Id
AAA-6002-2022
Scopus Author Id
57215717709

Email addresses

  • simao.teixeira@i3bs.uminho.pt (Professional)

Telephones

Fax
  • 253510909 (Professional)
Telephone
  • 253510912 (Professional)
  • 253510900 (Professional)

Addresses

  • I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho. Avepark - Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017, Barco, Guimarães, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Advanced (C1) Proficiency (C2) Upper intermediate (B2) Advanced (C1)
Japanese Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2018/09 - 2024/01/10
Concluded
 Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento)
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
"Molecular Imprinting Technologies for Growth Factor Sequestration and Control of Stem Cell Fate in Tendon Regeneration" (THESIS/DISSERTATION)
 Muito bom
2012/09 - 2017/10
Concluded
 Bioengenharia (Mestrado)
Major in Área de especialização: Biotecnologia Molecular
Universidade do Porto Faculdade de Engenharia, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Trimethyl-Chitosan-based Polyplexes for Neurotrophin Mimicking in Brain Ischaemia" (THESIS/DISSERTATION)
 17 valores
Affiliation

Science

Category
Host institution 		Employer
2018/09/01 - 2024/01/10 Researcher (Research) Laboratório Associado ICVS 3B's, Portugal
Biomaterials Biodegradables and Biomimetics, Portugal
2022/09/01 - 2022/12/20 Visiting Researcher (Research) Eidgenössische Technische Hochschule Zürich, Switzerland
Universitätsklinik Balgrist, Switzerland
2022/09/01 - 2022/12/20 Visiting Researcher (Research) Universität Zürich, Switzerland
Universitätsklinik Balgrist, Switzerland
2020/03/09 - 2020/03/30 Visiting Researcher (Research) University College London Eastman Dental Institute, United Kingdom

Others

Category
Host institution 		Employer
2017/02/06 - 2017/10/13 Estudante de Mestrado (tese)/Master Thesis student Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/02/15 - 2016/07/30 Estágio Erasmus+/Erasmus+ Traineeship Max Bergmann Center of Biomaterials Dresden, Germany
Projects

Grant

Designation Funders
2018/09 - 2023/04/05 Doctoral Program in Advanced Therapies for Health
PD/BD/143039/2018
PD/00169/2013
COVID/BD/153025/2022
PhD Student Fellow
Biomaterials Biodegradables and Biomimetics, Portugal

Laboratório Associado ICVS 3B's, Portugal
Fundação para a Ciência e a Tecnologia

European Social Fund
Concluded

Contract

Designation Funders
2023/03/01 - 2023/11/16 Wireless platform of abiotic nanoactuators to probe PIEZO receptors mechanobiology
10.54499/2022.05526.PTDC
2022.05526.PTDC
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 SmarTendon ? Growth Factors Sequestering Biomaterials to Engineer Living Tendon Grafts based on Molecularly Imprinted Nanoparticles
PTDC/NAN-MAT/30595/2017
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference paper
  1. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "3D Biomimetic Constructs Steer Stem Cell Commitment by Synergistic Modulation of Biophysical Cues and Growth Factor Signaling". Paper presented in EORS 2023 - 31st Annual Meeting of the European Orthopaedic Research Society, Porto, 2023.
    Published • 10.1302/1358-992X.2024.1.013
  2. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Bioinspired hydrogels promote tenogenic stem cell commitment by synergistic control over topographical cues and growth factor signaling". Paper presented in Tissue Engineering and Regenerative Medicine International Society European Chapter Conference (TERMIS-EU) 2023, Manchester, 2023.
    Published • 10.1089/ten.tea.2023.29043.abstract
  3. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Gomes, ME; Domingues, Rui M. A.. "Directing Stem Cell Commitment in 3D Bioinspired Hydrogels by Growth Factor Sequestration using Molecularly Imprinted Nanoparticles". Paper presented in TERMIS-EU 2022, Krakow, 2022.
    10.1089/ten.tea.2023.29046.abstracts
  4. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Bioinspired Composite Hydrogels Direct Stem Cell Fate Toward Tenogenesis by Synergistically Modulating Growth Factor Signalling and Local Microtopography". Paper presented in Final Achilles Conference, Guimarães, 2022.
  5. Teixeira, Simão P. B.; Domingues, Rui M. A.; Babo, Pedro S; Margarida S. Miranda; Manuela E. Gomes; Peppas, Nicholas A.; Reis, Rui L.. "Directing stem cell phenotype commitment by sequestering transforming growth factor-ß3 with epitope imprinted nanoparticles". Paper presented in 31st Conference of the European Society for Biomaterials (ESB), Porto, 2021.
Conference poster
  1. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Bioinspired Hydrogels Promote Tenogenic Stem Cell Commitment by Synergistic Control over Topographical Cues and Growth Factor Signaling". Paper presented in HEALTH-UNORTE Conference, 2023.
  2. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "3D Bioinspired Hydrogels with Molecularly Imprinted Nanoparticles Sequester Endogenous Growth Factors and Synergistically Direct Stem Cell Fate Commitment". Paper presented in ESB 2022 - 32nd Annual Conference of the European Society for Biomaterials, 2022.
  3. Teixeira, Simão P. B.; Pardo, Alberto; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Directing stem cell commitment in 3D bioinspired hydrogels by growth factor sequestration using molecularly imprinted nanoparticles". Paper presented in Third Achilles Workshop, 2021.
  4. Teixeira, Simão; Reis, Rui L.; Domingues, Rui M. A.; Gomes, Manuela E.. "Directing stem cell commitment toward tenogenesis by functionalizing tendon-mimetic grafts with epitope imprinted nanoparticles". Paper presented in Second Achilles Conference, 2019.
  5. Teixeira, Simão P. B.; Reis, Rui L.; Domingues, Rui M. A.; Manuela E. Gomes. "Directing stem cell commitment toward tenogenesis by functionalizing tendon-mimetic grafts with epitope imprinted nanoparticles". Paper presented in First Discoveries Forum on Regenerative and Precision Medicine, 2019.
  6. Teixeira, Simão P. B.; Reis, Rui L.; Domingues, Rui M. A.; Manuela E. Gomes. "Epitope-imprinted nanoparticles for TGF-ß3 sequestration and control of stem cell fate in tendon regeneration". Paper presented in First Achilles Conference, 2019.
Journal article
  1. Teixeira, Simão P. B.; Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Reis, Rui L.; Manuela E. Gomes; Domingues, Rui M. A.. "Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell-Scale Biophysical Cues in Bioengineered Constructs". Advanced Functional Materials (2024): 2312961. https://onlinelibrary.wiley.com/doi/10.1002/adfm.202312961.
    Open access • Published • 10.1002/adfm.202312961
  2. Pardo, Alberto; Bakht, Syeda Mahwish; Gomez-Florit, Manuel; Rial, Ramón; Monteiro, Rosa F.; Teixeira, Simão P. B.; Taboada, Pablo; et al. "Magnetically-Assisted 3D Bioprinting of Anisotropic Tissue-Mimetic Constructs". Advanced Functional Materials 32 50 (2022): 2208940. http://dx.doi.org/10.1002/adfm.202208940.
    Open access • Published • 10.1002/adfm.202208940
  3. Teixeira, Simão P. B.; Reis, Rui L.; Peppas, Nicholas A.; Manuela E. Gomes; Domingues, Rui M. A.. "Epitope-imprinted polymers: Design principles of synthetic binding partners for natural biomacromolecules". Science Advances 7 44 (2021): eabi9884. http://dx.doi.org/10.1126/sciadv.abi9884.
    Open access • Published • 10.1126/sciadv.abi9884
  4. Teixeira, Simão P. B.; Domingues, Rui M. A.; Babo, Pedro S; Berdecka, Dominika; Miranda, Margarida S.; Manuela E. Gomes; Peppas, Nicholas A.; Reis, Rui L.. "Epitope-Imprinted Nanoparticles as Transforming Growth Factor-ß3 Sequestering Ligands to Modulate Stem Cell Fate". Advanced Functional Materials 31 4 (2020): 2003934. http://dx.doi.org/10.1002/adfm.202003934.
    Published • 10.1002/adfm.202003934
  5. Teixeira, Simão P. B.; Domingues, Rui M. A.; Shevchuk, Mariya; Manuela E. Gomes; Peppas, Nicholas A.; Reis, Rui L.. "Biomaterials for Sequestration of Growth Factors and Modulation of Cell Behavior". Advanced Functional Materials 30 44 (2020): 1909011. http://dx.doi.org/10.1002/adfm.201909011.
    Published • 10.1002/adfm.201909011
Thesis / Dissertation
  1. "Molecular imprinting technologies for growth factor sequestration and control of stem cell fate in tendon regeneration". PhD, Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, 2024. https://hdl.handle.net/1822/88237.
  2. "Trimethyl-Chitosan-based Polyplexes for Neurotrophin Mimicking in Brain Ischaemia". Master, Universidade do Porto Faculdade de Engenharia, 2017. https://repositorio-aberto.up.pt/handle/10216/108361.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09 3D Biomimetic Constructs Steer Stem Cell Commitment by Synergistic Modulation of Biophysical Cues and Growth Factor Signaling EORS 2023 - 31st Annual Meeting of the European Orthopaedic Research Society
3B's Research Group (Porto, Portugal)
2022/06/29 Directing Stem Cell Commitment in 3D Bioinspired Hydrogels by Growth Factor Sequestration using Molecularly Imprinted Nanoparticles TERMIS European Chapter Conference 2022
Tissue Engineering and Regenerative Medicine International Society (Krakow, Poland)
2022/05 Bioinspired Composite Hydrogels Direct Stem Cell Fate Toward Tenogenesis by Synergistically Modulating Growth Factor Signalling and Local Microtopography Final Achilles Conference
3B's Research Group (Guimaraes, Portugal)
2021/09/09 Directing stem cell phenotype commitment by sequestering transforming growth factor-ß3 with epitope imprinted nanoparticles 31st Conference of the European Society for Biomaterials (ESB)
Institute for Research and Innovation in Health (i3S) and INEB – Instituto de Engenharia Biomédica, University of Porto, Portugal (Porto, Portugal)
2019/11/05 Directing stem cell commitment toward tenogenesis by functionalizing tendon-mimetic grafts with epitope imprinted nanoparticles Second Achilles Conference
3B's Research Group (Braga, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/09/27 - 2023/09/29 EORS 2023 - 31st Annual Meeting of the European Orthopaedic Research Society Local organizing committee (2023/09/27 - 2023/09/29)
Meeting (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2022/05/25 - 2022/05/27 Final Achilles Conference - "Tendon Regeneration: a throwback to the lessons learned and prospects to the future" Local organizing committee (2022/05/25 - 2022/05/27)
Conference (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2021/10/25 - 2021/10/27 Third Achilles Workshop - "Gene & Cell Therapy and Clinical Applications" Local organizing committee (2021/10/25 - 2021/10/27)
Workshop (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2019/11/04 - 2019/11/05 Second Achilles Conference - "Tendon Biophysical Environment" Local organizing committee (2019/11/04 - 2019/11/05)
Conference (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal
2019/07/08 - 2019/07/10 First Achilles Conference - "Molecular and Biological Mechanisms of Tendon Homeostasis and Repair" Local organizing committee (2019/07/08 - 2019/07/10)
Conference (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Biomateriais Biodegradáveis e Biomiméticos, Portugal

Committee member

Activity description
Role 		Institution / Organization
2020/03/01 - 2022/02/28 Representante dos estudantes de doutoramento do I3Bs na Comissão Coordenadora do Colégio Doutoral da Universidade do Minho
Member
 Universidade do Minho, Portugal
Distinctions

Award

2019 Best Rapid Fire Presentation - Second Achilles Conference
Biomaterials Biodegradables and Biomimetics, Portugal

Laboratório Associado ICVS 3B's, Portugal

Universidade do Minho, Portugal

EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation, Belgium

Fundação para a Ciência e a Tecnologia, Portugal