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Paulo J. Oliveira is currently Vice-President and Principal Investigator at the CNC - Center for Neuroscience and Cell Biology, University of Coimbra, Portugal, and Invited Assistant Professor in the same University. He is the current leader of the Mitochondria, Metabolism and Disease group. He received his Bachelor of Science in Biochemistry from the University de Coimbra in 1999. In 2003, he completed his PhD in Cellular Biology from the same University. After obtaining his Ph.D. degree, Paulo Oliveira spent more than three years performing research at the Medical School of the University of Minnesota, Duluth, USA, where he collaborated with several researchers and contributed to the publication of over 20 joint peer-reviewed manuscripts. Paulo Oliveira current research interests focus on mitochondrial biology, investigating the alteration of cardiac mitochondrial function by physical activity and diet, cardiac mitochondrial dysfunction and cell death caused by anti-neoplastic agents, mitochondrial alterations during cancer stem cell differentiation and carcinogenesis or rational designing of mitochondria-directed antioxidants. Paulo has about 300 peer-reviewed publications (h factor ~51, Scopus) and a large number of collaborations in Europe, Africa and in the USA. He has also received several prizes from the Portuguese Cardiology Society for his work on cardiac mitochondrial research, and recently won the FLAD Healthcare 2020 prize. Besides research, Paulo Oliveira is often involved in teaching at the Department of Life Sciences, University of Coimbra, as well as in other Universities in Portugal and elsewhere, besides participating in numerous science communication activities. Of importance, he has maintained a consistent primary role in the organization of national and international scientific meetings, including the International Courses in Toxicology (2005-2010 in Coimbra), Annual Meeting of the European Society for Clinical Investigation (2013, Albufeira, Portugal and 2019, Coimbra, Portugal), the 2014 Meeting of the Portuguese Biochemical Society (Coimbra), and FEBS Advanced Lecture Courses in Oncometabolism (2017, Figueira da Foz, Portugal and 2019 Luso, Portugal).From May 2019 to June 2022, Paulo J. Oliveira was the President of the European Society for Clinical Investigation (www.esci.eu.com), after being its Vice-President for 2 years. Paulo J. Oliveira has also been reviewer for more than 40 different scientific journals and over 10 different national and international funding agencies, including the European Commission (Research Executive Agency) and the Portuguese Foundation for Science and Technology. His research group is supported by competitive national and international funding agencies, including the Portuguese Foundation for Science and Technology, the European Commission, and private foundations. Paulo J. Oliveira is also currently member of the Board of Directors at CNC, as well as member of Board of Directors at CIBB (former CNC.IBILI consortium), the Center for Innovative Biomedicine and Biotechnology. In terms of technology transfer activities, Paulo J. Oliveira is co-inventor in two patents that were licensed to the CNC/University of Porto spin-off company MitoTAG, of which he is one of the co-founders. MitoTAG is a startup that develops targeting systems to deliver antioxidants to mitochondria in order to protect them from the damaging effects of oxidation. This platform technology has applications in diverse areas, namely as active ingredients for anti-aging cosmetics, active principles for the treatment of liver and neurodegenerative diseases, as well as anti-aging food supplements for pets. Finally, Paulo J. Oliveira is also very active in supervising Master (>16 past/present) and Ph.D. students (>30 past/present), as well as Postdocs (14 past/present), being also frequently invited to Master and Ph.D. defenses in Portugal and abroad.
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Identification

Personal identification

Full name
Paulo Jorge Gouveia Simoes Da Silva Oliveira

Citation names

  • Oliveira, Paulo J.

Author identifiers

Ciência ID
E41F-4FB7-5948
ORCID iD
0000-0002-5201-9948
Researcher Id
H-1980-2011

Email addresses

  • pauloliv@cnc.uc.pt (Professional)
  • pauloliv@ci.uc.pt (Professional)

Telephones

Fax
  • 231249179 (Professional)
Telephone
  • 231249235 (Professional)

Addresses

  • CNC - Center for Neuroscience and Cell Biology. UC Biotech Building, Lot 8A, Biocant Park, University of Coimbra, 3060-197, Cantanhede, Cantanhede, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism

Languages

Language Speaking Reading Writing Listening Peer-review
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2020/10/26 - 2020/10/26
Concluded
 Biologia Experimental e Biomedicina (Título de Agregado)
Universidade de Coimbra, Portugal
2003
Concluded
 Biologia (Doutoramento)
Major in Especialidade: Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Cardiac mithocondrial Function: Studies on the Impact of Disease Conditions and on the Protection Afforded by Carvedilol" (THESIS/DISSERTATION)
1999
Concluded
 Bioquimica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Efeito do Carvedilol ao Nível da Bioenergética Mitocondrial Cardíaca e da NADH Desidrogenase Externa Mitocondrial de Coração" (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2012/11/01 - Current Principal Investigator (Research) CNC.IBILI, Portugal
2006/11/01 - 2012/10/31 Auxiliary Researcher (Research) CNC.IBILI, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2016 - 2019 Invited Assistant Professor (University Teacher) Universidade de Coimbra, Portugal
2016 - 2019 Invited Assistant Professor (University Teacher) Universidade de Coimbra, Portugal

Positions / Appointments

Category
Host institution 		Employer
2023/07/01 - Current Member of the Trustof the Society ESCI - European Society for Clinical Investigation, Netherlands
2021/05/20 - Current Coordenador do Programa Doutoral em Biologia Experimental e Biomedicina Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2020/01/01 - Current Member of Board of Directors CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal
2020 - Current Vice-President Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/01/01 - Current Member of Board of Directors CNC.IBILI, Portugal
2019/05/22 - 2022/06/19 President ESCI - European Society for Clinical Investigation, Netherlands
2016/05/25 - 2019/05/22 Vice-President ESCI - European Society for Clinical Investigation, Netherlands

Others

Category
Host institution 		Employer
2014/02/01 - Current Leader, "Mitochondria, Metabolism and Disease Group" CNC.IBILI, Portugal
2006/11/01 - Current Principal Investigator, "MitoXT: Mitochondrial Pharmacology and Experimental Therapeutics" CNC.IBILI, Portugal
2013/03/28 - 2016/05/25 Councillor ESCI - European Society for Clinical Investigation, Netherlands
2013/06/01 - 2015/05/02 Board Member ESCI - European Society for Clinical Investigation, Netherlands
2006/02/01 - 2011/12/31 Leader "Mitochondrial Pharmacology and Toxicology Group" CNC.IBILI, Portugal
2003/03/01 - 2011 Adjunct Research Associate University of Minnesota Medical School - Duluth Campus, United States
2003/03/01 - 2006/10/30 Post-Doc fellow CNC.IBILI, Portugal
2000/01/01 - 2003/02/01 PhD fellow Universidade de Coimbra, Portugal
Projects

Contract

Designation Funders
2023/03/01 - 2028/08/31 PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
HORIZON-HLTH-2022-STAYHLTH- 101080329
Universidade de Coimbra, Portugal
 European Commission
Ongoing
2023/03/01 - 2027/02/28 EXCELScIOR
101087416
Researcher
Universidade de Coimbra, Portugal
 European Commission
Ongoing
2021/01/01 - 2025/12/31 Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado
LA/P/0058/2020
10.54499/LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/15 - 2025/01/14 Células Neuronais Humanas Diferenciadas a partir de Células Estaminais Derivadas de Urina como Plataforma para a Medicina Personalizada na Esclerose Lateral Amiotrófica
PTDC/BTM-ORG/0055/2021
Universidade de Coimbra, Portugal

CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2024/12/31 Lifelong exercise: modulating immunometabolic pathways for decreasing cancer risk.
10/22
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular, Portugal

Universidade de Coimbra Centro de Investigação do Desporto e da Actividade Física, Portugal

Unidade Local de Saúde de Coimbra EPE, Portugal
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
Ongoing
2023/03/10 - 2024/09/09 Desferrização da ataxia de Friedreich com quelantes inovadores direcionados para a mitocôndria
2022.04633.PTDC
Universidade do Porto Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/01 - 2024/08/31 Novas abordagens terapêuticas para a obesidade baseadas na sinalização dopaminérgica periférica
2022.05822.PTDC
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023 - 2024 Profiling the Impact of Physical Activity Using Infra-Red Spectroscopy and Machine Learning Non-Invasive Sampling
n.a.
Principal investigator
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundación Mapfre
Ongoing
2021/01/01 - 2023/12/31 Organelle-targeted Radiocomplexes for Auger Therapy of Cancer
PTDC/MED-QUI/1554/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Centro de Ciências e Tecnologias Nucleares, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 Função da homeostasia tiol-mitocondrial na neurodegeneração: implicações para a esclerose lateral amiotrófica
EXPL/BTM-TEC/1407/2021
Universidade de Coimbra, Portugal

CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 Mitocôndria como potencial mediador do dimorfismo sexual nas alterações pato-morfológicas da microglia e ansiedade causadas pelo stress pré-natal<br>
EXPL/MED-NEU/1002/2021
Universidade de Coimbra, Portugal

CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/07/01 - 2023/06/30 Preservação do património natural e cultural e validação científica das práticas com plantas medicinais do Vale do Côa
COA/BRB/0019/2019
Universidade de Coimbra, Portugal

CNC.IBILI, Portugal

Instituto Politécnico de Bragança, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/06/01 - 2023/05/31 Proof of Concept “MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease
181226
Principal investigator
CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal
 Agência para a Competitividade e Inovação IP
Ongoing
2018/06/01 - 2022/02/28 Eficácia pré-clínica do sulforafano ou do extrato total de Brássicas: uma estratégia para combater a obesidade e valorizar os subprodutos de Brássicas
PTDC/ASP-HOR/29152/2017
Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/01 - 2022/01/31 O papel do metabolismo extra-hepático da frutose no desenvolvimento de doença hepática gordurosa não alcoólica
PTDC/BIA-BQM/28147/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Aveiro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/26 - 2021/07/25 Uso de fitoquímicos redox-activos para desencadear a hormesis mitocondrial: Desenvolvimento de uma nova geração de ingredientes para a cosmética
PTDC/BIA-MOL/28607/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2021 - 2021 Summer with Science: Research, Development and Interdisciplinary Innovation in the Physiolopathology of Aging and Lifestyle-dependent Diseases
n.a.
Principal investigator
CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2021 MitoSHIELD - Redox-active Phytochemicals Triggering Mitochondrial Hormesis: Developing a New Generation of Cosmetic Active Ingredients
PTDC/BTM-SAL/29297/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 The Role of Visceral Fructose Metabolism in the Development of Non-alcoholic Fatty Liver Disease
02/SAICT/2017/028147
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 Development and validation of innovative screening methods for mitochondrial health modulators
PTDC/BTM-SAL/29297/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 MitoCIN- Hydroxycinnamic derivatives, methods and uses thereof, Intelectual Protection Support
Portugal2020/call 17/SI/2015/37586
Principal investigator
Ongoing
2018 - 2021 Development of mitochondriotropic antioxidants based on a hydroxybenzoic acid scaffold, Intelectual Protection Support
Portugal2020/call 04/SAICT/2017/037892
Principal investigator
Ongoing
2018 - 2021 VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproducts
POCI-01-0145-FEDER-029152
POCI-01-0145-FEDER-029152
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 Mito4ALS: Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype
PTDC/MED-FAR/29391/2017
PTDC/MED-FAR/29391/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/07 - 2020/06 mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease
734719
Principal investigator
European Commission
Ongoing
2020 - 2020 Summer Course: Methodologies for Scientific Research – Interdisciplinary Research, Development and Innovation in Cell and Molecular Metabolism
15-20/7/245
Principal investigator
CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/01 - 2019/12 FOIE GRAS - Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease
722619
Principal investigator
European Commission
Ongoing
2016/04/01 - 2019/09/30 EXERCITANDO O FUTURO: Exercício Voluntário Durante Diabetes Gestacional com uma Estratégia para Melhorar a Função Mitocondrial na Descendência
PTDC/DTP-DES/1082/2014
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto Faculdade de Desporto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/04/01 - 2019/09/30 MitoBOOST: Uma Terapeutica de Nova Geração para a Doença de Fígado Gordo Não Alcoólico Baseado na Entrega Inteligente de Antioxidantes à Mitocôndria
PTDC/DTP-FTO/2433/2014
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2019 Tackling CANcer STEM CELls: A Challenge and an Opportunity to Advance in Anti-cancer Therapy
SAICTPAC/0022/2015
SAICTPAC/0022/2015
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2016 - 2019 Exercising obesity - The Role of Exercise Against Endoplasmic Reticulum Stress in Obesity-induced Liver Disease
PTDC/DTP-DES/7087/2014
PTDC/DTP-DES/7087/2014
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2015/10 - 2018/09 EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring
grant.Provided by PTCRIS: 139707
Researcher
CNC.IBILI, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015/10 - 2018/09 MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria
grant.Provided by PTCRIS: 141059
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2018 Mitochondrial-derived Peptides in Cell Homeostasis
FLAD Healthcare 2020
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação Luso-Americana
Concluded
2015 - 2018 FishFree: A Contribution to the Validation of an Alternative Assay for Fish Lethal Ttesting
PTDC/AAG-TEC/4966/2014
PTDC/AAG-TEC/4966/2014
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014 - 2016 An Epigenetic Engineering Approach to Reverse the Parkinson Disease (PD) Cell State (co-investigator)
n.a.
Principal investigator
Montepio Geral - private Bank
Concluded
2014 - 2015 Hypercholesterolemia as a risk factor for Alzheimer’s Disease: impact on nitric oxide bioavailability and bioactivity
8. Transnational Cooperation Agreement Project, CAPES/FCT 2013
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013 - 2015 Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link
PTDC/DTP-FTO/1180/2012
PTDC/DTP-FTO/1180/2012
Principal investigator
Foundation for Science and Technology - Portugal
Concluded
2011/03/01 - 2014/08/31 Actividade Protectora da SIRT3 na Disfunção Mitocondrial Induzida por Fármacos
PTDC/SAU-TOX/110952/2009
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2014 Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction
PTDC/SAU-TOX/110952/2009
PTDC/SAU-TOX/110952/2009
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Foundation for Science and Technology - Portugal
Concluded
2010/05/01 - 2013/10/30 Clarificação do Papel Mitocondrial na Cardiotoxicidade da Doxorubicina Usando um Sistema de Perfusão de Corações Intactos - Papel de Diferentes Calendários de Tratamento com Doxorubicina
PTDC/SAU-OSM/104731/2008
PTDC/SAU-OSM/104731/2008
Researcher
Instituto do Mar, Portugal

University of Minnesota Twin Cities School of Medicine Duluth Campus, United States

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/03/31 A Abertura da Caixa de Pandora Para uma Terapia Activa Anti-cancro da Mama - O Papel do Direccionamento Selectivo da Mitocôndria
PTDC/QUI-QUI/101409/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Mercer University School of Medicine, United States

University of Minnesota Medical School - Duluth Campus, United States

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/03 Opening Pandora's Box for Active Anti-Breast Cancer Therapy - The Role of Selective Targeting to Mitochondria
101409
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010 - 2013 Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics
PTDC/QUI-BIQ/101052/2008
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Foundation for Science and Technology - Portugal
Concluded
2010 - 2013 Metabolism as a Modulator of Stem Cell Pluripotency and Differentiation
PTDC/EBB-EBI/101114/2008
PTDC/EBB-EBI/101114/2008
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Foundation for Science and Technology - Lisbon
Concluded
2010 - 2013 Can Phytoestrogens be Safe and Effective Food Additives for Women During Menopause? - An In Vitro and In Vivo Approach to the problem
PTDC/AGR-ALI/108326/2008
PTDC/AGR-ALI/108326/2008
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Foundation for Science and Technology - Portugal
Concluded
2010 - 2013 Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics
PTDC/QUI-BIQ/101052/2008
 Foundation for Science and Technology - Portugal
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2012 MitocancerStem ¿ Role of Mitochondrial Physiology in Tumor Cell Resistance to Chemotherapeutics
FP7-People-2009-IEF 251850
 European Commission
2009 - 2011 Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study
PTDC/QUI/66701/2006
PTDC/QUI/66701/2006
Researcher
Foundation for Science and Technology - Portugal
Concluded
2007/09/15 - 2010/03/13 Novos Mecanismos Mitocondriais Para a Toxicidade Cardioselectiva da Doxorubicina
PTDC/SAU-OSM/64084/2006
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto Centro de Investigação em Actividade Física Saúde e Lazer, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/09/15 - 2010/03/13 Novel Mitochondrial Mechanisms for the Cardioselective Toxicity of Doxorubicin
PTDC/SAU-OSM/64084/2006
Universidade do Porto Centro de Investigação em Actividade Física Saúde e Lazer, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007 - 2009 Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells - Signalling Pathways Involved
PTDC/QUI/64358/2006
PTDC/QUI/64358/2006
Researcher
Foundation for Science and Technology - Portugal
Concluded
2005/07/01 - 2008/09/30 Influência das Soluções de Preservação para Transplante nos Perfis Metabólico e Imunológico Cardíacos
POCI/SAU-OBS/55802/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005 - 2008 Development of Novel Anticancer Agents: Phenolic Derivatives of Natural and Synthetic Origin - Structure-Activity Relationships
POCTI/QUI/55631/2004
Researcher
Foundation for Science and Technology - Portugal
Concluded
2005/10/15 - 2007/04/15 Desenvolvimento de Novos Agentes Anticancerígenos: Derivados Fenólicos de Origem Natural ou Sintética - Relações Estrutura-Actividade
POCI/QUI/55631/2004
Universidade de Coimbra, Portugal

Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2003/02/15 - 2006/10/14 ADRIAMYCIN - ASSOCIATED CARDIOMYOPATHIES - IMPACT OF METABOLIC THRESHOLDS IN SELECTIVE ORGAN TOXICITY AND DIFFERENTIAL ACTIVATION OF MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS
SFRH/BPD/8359/2002
 Fundação para a Ciência e a Tecnologia
Concluded
2000/01/01 - 2003/01/31 UTILIZAÇÃO SISTEMÁTICA DE CARDIOMIÓCITOS E DE MITOCÔNDRIAS CARDÍACAS ISOLADAS COMO MODELO DE AVALIAÇÃO FARMACOLÓGICA E TOXICOLÓGICA DE FÁRMACOS COM ACÇÃO A NÍVEL CARDÍACO
PRAXIS XXI/BD/21494/99
 Fundação para a Ciência e a Tecnologia
Concluded
2000 - 2003 Mitochondria and diabetes: mitochondrial function in the brain and heart of non-insulin dependent animal models (Goto-Kakizaki)
POCTI/ESP/43642/1999
POCTI/ESP/43642/1999
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2022/01/15 - 2025/01/14 Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Gonçalo J.M. Afonso; Rui F. Simões; Sonia L.C. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Challenges in mitochondrial profiling during pre-clinical studies". 2023.
    10.1016/B978-0-323-88462-4.00002-X
  2. Duarte, Ana I.; Sadowska-Bartosz, Izabela; Karkucinska-Wieckowska, Agnieszka; Lebiedzinska-Arciszewska, Magdalena; Palmeira, Carlos M.; Rolo, Anabela P.; Kabiri, Yaschar; et al. "A metabolic and mitochondrial angle on aging". In Aging, edited by Oliveira PJ; Malva JO, 175-256. Elsevier, 2023.
    Published • 10.1016/b978-0-12-823761-8.00024-0
  3. Cagide, Fernando; Oliveira, Catarina; Teixeira, José; Oliveira, Paulo J.; Borges, Fernanda. "Bridging the Gap Between Nature and Antioxidant Setbacks: Delivering Gallic Acid to Mitochondria". In Methods in Molecular Biology, 161-172. Springer US, 2021.
    10.1007/978-1-0716-1262-0_10
  4. Ferreira, Luciana L.; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Corresponding author: # Cunha-Oliveira, Teresa. "Epigenetics in Doxorubicin Cardiotoxicity". In Pharmacoepigenetics, edited by Cacabelos, Ramón, 837-846. Elsevier, 2019.
    Published • 10.1016/b978-0-12-813939-4.00033-4
  5. Simões, Rui F.; Cunha-Oliveira, Teresa; Costa, Cláudio F.; Sardão, Vilma; Oliveira, Paulo. "In Vitro Methodologies to Investigate Drug-Induced Toxicities". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 229-247. John Wiley & Sons, Inc., 2018.
    Published • 10.1002/9781119329725.ch14
  6. Silva, Filomena S. G.; Costa, Cláudio F.; Marques, Ricardo J.; Oliveira, Paulo J.; Pereira, Gonçalo C.. "Pharmacological Targeting of the Mitochondrial Permeability Transition Pore for Cardioprotection". In Mitochondrial Biology and Experimental Therapeutics, edited by Oliveira, Paulo J., 423-490. NewYork: Springer International Publishing, 2018.
    Published • 10.1007/978-3-319-73344-9_20
  7. Deus, Cláudia; Branco, Ana F.; Oliveira, Paulo J.; Sardão, Vilma. "Caffeine Cardiovascular Toxicity". In Coffee in Health and Disease Prevention, 699-707. Elsevier, 2015.
    10.1016/b978-0-12-409517-5.00078-4
  8. Marques-Aleixo, Inês; Santos-Alves, Estela; Moreira, Paula I.; Oliveira, Paulo J.; Magalhães, José; Ascensão, António; Marques-Aleixo, I.; et al. "Exercise-Induced Protection Against Aging and Neurodegenerative Diseases". In Diet and Exercise in Cognitive Function and Neurological Diseases, 309-321. John Wiley & Sons, Inc, 2015.
    10.1002/9781118840634.ch26
  9. Moreira, Ana; Machado, Nuno; Bernardo, Telma; Sardao, Vilma; Oliveira, Paulo J.. "Mitochondria as a Biosensor for Drug-induced Toxicity ¿ Is It Really Relevant?". In Biosensors for Health, Environment and Biosecurity. InTech, 2011.
    Published • 10.5772/17805
Conference abstract
  1. Marques, M. Pedro; Landim, Euclides; Varela, Carla; MARQUES, JOANA; da Costa, Ricardo MF; Carvalho, Aida; Oliveira, Paulo J.; Cabral, Célia. "Valorization of the neglected species Verbascum pulverulentum Vill. from Côa Valley for possible cosmetic applications". Paper presented in III Bio.Natural 2023 - Bioactive Natural Products Research Conference, Lisbon, 2023.
    Accepted
  2. Sousa, Diana; Amaro, A; Ferreira Junior, Marcos Divino; Susana P. Pereira; Rocha, Mariana; Barra, Cátia; Mello-Gomes, Rodrigo; Oliveira, Paulo; Matafome, Paulo. "Exposure to obesogenic environments during perinatal development modulates offspring nutrient sensing pathways in adipose tissue.". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, 2022.
    Published
  3. Melim, Catarina; Teixeira, José; Varela, Carla; Marques, Mário; Sardão, Vilma; Oliveira, Paulo; Célia Cabral. "Potential of Côa Valley (Portugal) Plants Extracts in Cell Model for Hepatic Lipid Toxicity". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Bari, 2022.
    Published
  4. Teixeira Camila; Marques CC; Baptista MC; Pimenta, J.; Teixeira, José; Cagide F; Borges, F; et al. "Effect of a new mitochondriotropic antioxidant on oocyte maturation and embryo production". Paper presented in 71st Annual Meeting of European Federation of Animal Science (EAAP), Porto, 2020.
    Published
  5. Diniz, Mariana S.; Grilo, Luís F.; João D. Martins; Stephen Ford; Peter W. Nathanielsz; Oliveira, Paulo J.; Susana P. Pereira. "Maternal obesity (MO) during pregnancy: are there implications for maternal hepatic mitochondrial activity?". Paper presented in ESCI Virtual Meeting 2020, 2020.
    10.1111/eci.13369
  6. Marques, R; Oliveira, Paulo; Oliveira GL. "ANT2 Silencing Promotes a Metabolic Shift in P19 Embryonal Carcinoma Stem Cells". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
    https://doi.org/10.1111/eci.13127
  7. Marques, R; Silva MR; Oliveira, Paulo. "P-cadherin effect in mitochondrial dynamics and biogenesis of breast cancer cells". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
    10.1111/eci.13127
  8. Ana M Silva; Videira, Romeu; Moreira, Ana C.; Oliveira, Paulo; Carvalho, RA; Carvalho, R; Carvalho Rui; Sardão, Vilma. "Delving the Bone-buried Osteocytes lipid metabolism commitment in post-menopausal osteoporosis.". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
  9. Santos-Alves, Estela; Marques-Aleixo, Inês; Coxito, Pedro; Balça, Maria Manuel; Rizo-Roca, David; Torrella, J. Ramon; Oliveira, Paulo J.; et al. "Doxorubicin and physical exercise modulate hepatic mitochondrial bioenergetics, oxidative stress, apoptotic signaling, dynamics and quality control". Paper presented in 48th annual scientific meeting of the European Society for Clinical Investigation. European Journal of Clinical Investigation., Utrecht, 2014.
    Published
  10. Pereira, S P; Oliveira, Paulo J.; Tavares, L C; Duarte, A I; Baldeiras, I; Santos, Maria S; Cox, L A; et al. "Implications of Maternal Nutrient Reduction on Fetal Nonhuman Primate Cardiac Mitochondria at 0.65 Gestation (G).". Paper presented in XVIII Congress of the Portuguese Biochemical Society, Coimbra, 2014.
    Published
  11. Monteiro, João P.; Ana M Silva; Jurado, Amália S.; Oliveira, Paulo. "Rapeseed oil-rich diet impacts hepatic mitochondrial physiology and in vitro menadione and nimesulide toxicity". Paper presented in 47th Annual Meeting of the European Society of Clinical Investigation, Albufeira, 2013.
  12. Gonçalves IO; Emanuel Passos; Rocha-Rodrigues, Sílvia; Cátia V. Diogo; Santos-Alves, Estela; Oliveira, Paulo J.; António Ascensão; José Magalhães. "The preventive role of voluntary physical activity against high-fat diet induced liver mitochondrial dysfunction". Paper presented in Eur J Clin Invest, Albufeira, 2013.
    Published
  13. Gonçalves IO; Emanuel Passos; Rocha-Rodrigues, Sílvia; Cátia V Diogo; Estela Santos-Alves; Oliveira, Paulo J.; António Ascensão; José Magalhães. "Modulation of liver mitochondrial bioenergetics and apoptotic signaling by endurance training in high-fat diet fed rats". Paper presented in Eur J Clin Invest, Albufeira, 2013.
    Published
  14. Gonçalves IO; Emanuel Passos; Rocha-Rodrigues, Sílvia; Cátia V. Diogo; Santos-Alves, Estela; Oliveira, Paulo J.; Ascensão, António; Magalhães, J.. "Preventive and Therapeutic effects of physical exercise against obesity: study of clinical and anthropometric variables in rats fed with hipercaloric diets". Paper presented in 47th Annual Scientific Meeting of the European Society for Clinical Investigation, Albufeira, 2013.
  15. António Ascensão; Gonçalves IO; Lumini-Oliveira, José; Marques-Aleixo, Inês; Emanuel Passos; Rocha-Rodrigues, Silvia; Nuno Machado; et al. "Modulation of liver mitochondrial bioenergetics by endurance training and chronic intermittent hypobaric hypoxia. Relevance for salicylate-induced mitochondrial dysfunction". Paper presented in Eur J Clin Invest, Budapeste, 2012.
    Published
  16. Ascensão, António; Gonçalves IO; Lumini-Oliveira, José; Marques-Aleixo, Inês; Emanuel Passos; Rocha-Rodrigues, Sílvia; Nuno Machado; et al. "Endurance Training and Chronic Intermittent Hypobaric-Hypoxia Modulate Liver Mitochondrial Bioenergetics. Role Against Salicylate-Induced Mitochondrial Dysfunction". Paper presented in Med Sci Sports Exerc, 2012.
  17. Mota, Paula C.; Tavares, Renata S.; Cordeiro, M.; Pereira, Susana P.; Oliveira, Paulo J.; Ramalho-Santos, João. "Acute effects of TCDD administration on spermatogenesis and sperm: special emphasis on mitochondrial function". Stockholm, 2012.
    Published
  18. Moreira, Ana C.; Ana M Silva; Oliveira, Paulo; Santos, Maria Sancha; Holy, John; Sardão, Vilma. "Estrogen Dependent Effects on Breast Cancer Cell Motility and Proliferation". Paper presented in XLI Annual Meeting of the Portuguese Society of Pharmacology, Coimbra, 2011.
  19. Martins, Fatima; Margarida, Ana; Oliveira, Maria M.; Oliveira, Paulo J.; Francisco Peixoto. "Toxicity of parabens in testis mitochondria; a possible role on male infertility". 2011.
    Published • 10.1016/j.bbabio.2008.05.239
  20. Diogo, C. V.; Félix, L.; Vilela, S.; Burgeiro, A.; Barbosa, I.A.; Carvalho, M.J.M.; Oliveira, Paulo J.; et al. "Possible anti-cancer application of the phytochemicals daphnetoxin and daphnoretin-relevance of mitochondrial toxicity". Paper presented in 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, 2010.
    Published
  21. Alves, Marco G.; Martins, Fátima O.; Oliveira, Paulo J.; Carvalho, Rui A.. "Energy metabolism assessment during heart preservation in celsior and histidine buffer solution by 1H-NMR spectroscopy". Paper presented in 34th Federation of european Bichemical societies (FEBS) congress, Praga, 2009.
    Published
Conference paper
  1. Magalhães, M; Domínguez Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Oliveira, Paulo J.; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia. "Unravelling an abietane diterpenoid with very promising chemotherapeutic potential against glioblastoma cells". Paper presented in 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Dublin, 2023.
    Published • 10.1055/s-0043-1774254
  2. Magalhães, M; Domínguez-Martín, EM; Jorge, Joana; Gonçalves, Ana Cristina; Duarte, Ana ; Oliveira, Paulo J.; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia. "EACR23-0331 | Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma". Paper presented in EACR 2023 Congress: Innovative Cancer Science, Torino, 2023.
    Published • 10.1002/1878-0261.13471
  3. Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo M.F. da; Carvalho, Luís A.E. Batista de; Carvalho, Aida; Oliveira, Paulo J.; Cabral, Célia. "Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and antioxidant assessment". 2023.
  4. Miranda-Santos, I.; Pereira, Carolina; Pinho, Sónia Andreia; Oliveira, Paulo J.; Cunha-Oliveira, T.. "Visualization of metabolic rewiring of NHDF cells in response to extracellular glucose concentration". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  5. *Cunha-Oliveira, T.; Carvalho, M.; Sardão, V.; Oliveira, Paulo J.; Silva, Filomena S.G.. "Multi-dimensional Analysis of Metabolic and Mitochondrial Dysfunction Parameters in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  6. Afonso, Gonçalo; Inês Miranda-Santos; Carvalho, RA; Carvalho, R; Carvalho Rui; Oliveira, Paulo J.; Cunha-Oliveira, T.. "Impact of Rebaudioside A in the metabolism of breast cancer cells and assessment of its chemotherapeutic potential". Paper presented in ESCI Virtual Meeting 2020 ¿ COVID19 edition, 2020.
    Published
  7. Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S; Garcia, Rita; Burgeiro, Ana; Lourenço, Nuno; Carvalho, RA; Carvalho, R; Carvalho Rui; Oliveira, Paulo J.. "A Data Science Approach to Sub-chronic Doxorubicin Cardiotoxicity Reveals Hidden Patterns of Metabolic Remodeling". Paper presented in ESCI Virtual Meeting 2020 - COVID19 edition, 2020.
    Published
  8. Coelho, Ana R; J. Kovarova; M. Bajzikova; J. Rohlena; Oliveira, Paulo J.; Jiri Neuzil. "Mitochondrial dihydroorotate dehydrogenase plays an important role in tumor formation". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
  9. Tavares, Rui; Ramalho-Santos, João; Oliveira, Paulo J.; Azul, Anabela Marisa. "Using Comics to Bring Mitochondria to ¿Real-Life¿". Paper presented in 6th International Conference for Illustration and Animation, Esposende, 2018.
    Published
  10. Ferreira, Fernanda M.; Pereira, Olívia R.; Cardoso, Susana M.; Oliveira, Paulo J.; Moreno, António J.M.. "Potential noxious effect of mentha aquatica L. on mitochondrial bioenergetics". 2015.
Conference poster
  1. Magalhães, M; Dionísio, Pedro A.; Oliveira, Paulo J.; Efferth, Thomas; Rijo, Patrícia; Raimundo, Nuno; Cabral, Célia. "How does the natural compound 7a-acetoxy-6ß-hydroxyroyleanone (Roy) modulates glioblastoma cells autophagy?". Paper presented in Mitochondria in Aging, Cancer and Cell Death (MAC) 2023: A Gathering of Experts in Mitochondria Research, 2023.
  2. Melim, Catarina; Amorim, Ricardo; Marques, Mário Pedro; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Teixeira, José; Oliveira, Paulo J.; Cabral, Célia. "Efeito hepatoprotetor de plantas do Vale do Côa (Portugal) num modelo celular de doença do fígado gordo não alcoolico (DFGNA)". Paper presented in XXVII Encontro Luso Galego de Química, 2023.
  3. Marques, Mário P.; Euclides Landim; Joana Marques; da Costa, Ricardo MF; Luis Baptista de Carvalho; Dias, Maria Inês; Barros, Lillian; et al. "Cistus Species from Côa Valley: a Source of Antioxidants for Natural-based Cosmetics". Paper presented in Mitochondria in Aging, Cancer and Cell Death (MAC), 2023.
  4. Nunes, Mara; Marques-Carvalho, Adriana; Marques, Mário Pedro; Varela, Carla; Sardão, Vilma A.; Dias, Maria Inês; Barros, Lillian; et al. "Exploring the inhibitory effects of Côa valley plant extracts on osteoclast differentiation: Chemical characterization and cytotoxicity". Paper presented in II Bio Natural - Bioactive Natural Compounds Research Meeting, 2023.
  5. Magalhães, M; Domínguez-Martín, EM; Jorge, Joana; Gonçalves, Ana Cristina; Duarte, Ana I.; Oliveira, Paulo J.; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia. "Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma". Paper presented in EACR 2023 Congress: Innovative Cancer Science, 2023.
  6. Amorim, Ricardo; Melim, Catarina; Marques, Mário P.; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Teixeira, José; Oliveira, Paulo; Célia Cabral. "Protective Effects of Equisetum ramosissimum Desf. Against Palmitic Acid-induced Lipid Accumulation and Mitochondrial Dysfunction in Human HepG2 Cells". Paper presented in 57th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), 2023.
  7. Barreiro, Sandra; Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; Cagide, Fernando; Sequeira, Lisa; Teixeira, José; et al. "Nitrogen-based cationic carriers as a game changer in the development of mitochondriotropic antioxidants". Paper presented in MitoPorto 2023 - Mitochondrial physiology, redox biology, and genetics, 2023.
  8. Gerardo, Heloísa; Amorim, Ricardo; Ines CM Simoes; Cavadas, Claudia; Wieckowski Mariusz R.; Oliveira, Paulo J.; Grãos, Mário; Teixeira, José. Corresponding author: Teixeira, José. "O impacto da síndrome metabólica na interação entre metabolismo mitocondrial e mecanotransdução em cérebros de murganhos sujeitos a uma dieta ocidental". Paper presented in 19º Congresso Portugês de Diabetes, 2023.
  9. Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; Barreiro, Sandra; Cagide, Fernando; Silva, Catia; Teixeira, José; et al. "Synthesis and in vitro evaluation of versatile cell-penetrating mitochondriotropic antioxidants". Paper presented in XXVI Encontro Galego-Portugués de Química, 2022.
  10. Chavarria, Daniel; Benfeito, Sofia; Garrido, Jorge; Serrão, Paula; Soares-da-Silva, Patrício; Remião, Fernando; Oliveira, Paulo; Borges, Fernanda. "Tackling dopamine depletion and oxidative stress with innovative caffeic acid derivatives". Paper presented in X Meeting of the Paul Ehrlich Euro-PhD Network, 2022.
  11. Ilina, V.; Teixeira, José; Varela, Carla; Marques, Mário; Sardão, Vilma; Melim, Catarina; Baranenko, D.; Oliveira, Paulo; Cabral, Célia. "In Vitro Cardioprotective Potential of Côa Valley (Portugal) Plants Extracts Against Lipotoxic Insults". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), 2022.
  12. Mena, Débora; Pedro Soares; Cagide, Fernando; Benfeito, Ester; Grilo, Luís F.; Daniela F. Silva; Valente, Pedro; et al. "The Mitochondria-Targeted Antioxidant Antioxcin4 Protects Against Oxidative/Nitrosative Stress in the Amyotrophic Lateral Sclerosis SOD1GG3A Mouse". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  13. Salermo, A.; Albertini, C.; Atzeni, S.; Uliassi, F.S.G.; Massenzio, F.; Monti, B.; Chavarria, Daniel; et al. "Combining riluzole/dexpramipexole and rasagiline in new multi-target-directed ligands in the context of Amyotrophic Lateral Sclerosis". Paper presented in 13th Young Medicinal Chemist Virtual Symposium, 2021.
  14. C. Teixeira; C. Marques ; M.C. Baptista; Jorge Pimenta; Teixeira, José; Cagide, Fernando; Borges, Fernanda; et al. "Beneficial effects of mitochondriotropic antioxidants on oocyte maturation and embryo production". Paper presented in 54th Annual meeting of the European Society for Clinical Investigation, “COVID-19 edition, 2020.
    10.1111/eci.13109
  15. Simões, Rui F.; Cunha-Oliveira, Teresa; Oliveira, Paulo; Pereira, Francisco. "Differentiated SH-SY5Y cells as a cellular model to study mitochondrial physiology and dynamics". Paper presented in 54th Annual Scientific Meeting of the European Society for Clinical Investigation, COVID Edition, 2020.
  16. Marques, R; Serafim, Teresa; Deus CM; Silva, F.S.G.; Sardão, Vilma; Dias, Sérgio; Oliveira, Paulo. "Glucose dependence and metabolic reprogramming of commercial breast cancer cells.". Paper presented in EACR-AACR-ASPIC Conference on Tumor Microenvironment, 2020.
  17. Silva FSG; Cunha-Oliveira T; Silva, D.F; Daniela Silva; Daniela F. Silva; Luis Segura; Ricardo Marques; Tatiana Rosenstock; Oliveira, Paulo. "Oxidant/antioxidant imbalance in lymphoblast from amyotrophic lateral sclerosis patients with SOD1 mutations and unknown mutations". Paper presented in 11th World Congress on Targeting Mitochondria, 2020.
  18. Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S.; Garcia, Rita; Burgeiro, Ana; Carvalho, Rui; Oliveira, Paulo J.; Lourenço, Nuno. "Unraveling metabolic effects underlying acute cardiotoxicity of the antineoplastic drug Doxorubicin". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  19. Silva, Filomena S.G.; Cunha-Oliveira, T.; Bento, Guida; Oliveira, Paulo J.. "Data mining analysis of respiratory and glycolytic fluxes from amyotrophic lateral sclerosis patients: Unraveling the effect of SOD1 mutation.". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  20. Marques, R; Carvalho, M; Borges D; Oliveira, Paulo; Silva FSG. "Alterations in mitochondrial biogenesis and regulation of morphology in lymphoblasts from amyotrophic lateral sclerosis patients.". Paper presented in 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  21. Marques, R; Borges D; Carvalho, M; Oliveira, Paulo; Silva FSG. "Understanding the influence of SOD1 mutation on mitochondrial mechanisms of autophagy and apoptosis in lymphoblasts from amyotrophic lateral sclerosis patients". Paper presented in 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  22. Marques, R; Sousa, Bárbara; Sardão, Vilma; Schmitt, F.; Oliveira, Paulo; Paredes, Joana. "P-cadherin induces anoikis resistance in breast cancer stem cells by rewiring the metabolic flux and activating of antioxidant systems". Paper presented in 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  23. Marques, R; Oliveira, G.; Oliveira, Paulo. "Adenine Nucleotide Translocase 2 silencing induces metabolic remodelling in P19 embryonal carcinoma stem cells". Paper presented in . 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  24. Marques, R; Deus C; Silva, F.S.G.; Sardão, Vilma; Oliveira, Paulo; Serafim, Teresa. "Metabolic reprogramming forwards oxidative phosphorylation in breast cancer cells as potential drug targets". Paper presented in 2nd FEBS 2019 Advanced Course on Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  25. Simões, Rui F.; Cunha-Oliveira, Teresa; Oliveira, Paulo; Pereira, Francisco. "Early mitochondrial metabolism and dynamics changes as predictors of neurodegeneration and neuronal cell death". Paper presented in 53rd Annual Scientific Meeting of European Society for Clinical Investigation, 2019.
  26. Bento, Guida; Oliveira, Paulo; Macedo, Maria; Sardão, Vilma. "Human urine-derived cells from young and old donors for assessing glycolytic and oxidative phosphorylation functions.". Paper presented in MitoPorto ¿ Mitochondrial evolution, metabolism and diseases, International symposium, University of Porto, Portugal,, 2018.
  27. Simões, Rui F.; Cunha-Oliveira, Teresa; Oliveira, Paulo; Pereira, Francisco. "Dose-dependent analysis of mitochondrial parameters in differentiated SH-SY5Y cells exposed to mitochondrial toxicants". Paper presented in 2nd Edition MitoPorto, 2018.
  28. Fonseca, Ana Catarina; Burgeiro, Ana; Dias, Cândida; Baldeiras, Inês; Cunha-Oliveira, Teresa; Lourenço, Nuno; Costa-Nunes, João; et al. "Mitochondrial function and oxidative stress in diabetic and non-diabetic human epicardial versus subcutaneous adipose tissue.". Paper presented in Mitoporto, Mitochondrial evolution, metabolism and disease,, 2018.
  29. Marques, R; Sousa, B.; Pereira, J.; Nobre AR; Carneiro P,; Sardão, Vilma; Schmitt, F.; Oliveira, Paulo; Paredes, Joana. "P- Cadherin promotes anoikis resistance in breast cancer stem cells by stimulating the glycolytic behavior and lowering the oxidative". Paper presented in 3rd ASPIC International congress, 2018.
  30. Teixeira, Jose; Amorim, Ricardo; Santos, Katia; Sardão, Vilma; Soares, Pedro; Serafim, Teresa; Garrido, Jorge; Oliveira, Paulo; Borges, Fernanda. "In vitro characterization of potential biological applications of MITOK3, A NOVEL Mitocondriotropic Menadione derivative, EpiChemBio (CM1406) and MuTaLig (CA15135)". Paper presented in COST actions joint meeting 2017, Porto, Portugal,, 2017.
  31. Sardão, Vilma; Bento, Guida; Oliveira, Paulo. "Mitochondrial bioenergetic profile of human urine-derived stem cells.". Paper presented in MitoPorto ¿ Advances in mitochondrial research, International symposium, University of Porto, Portugal, 2017.
  32. Teixeira, Jose; Amorim, Ricardo; Santos, Katia; Soares, Pedro; Sardão, Vilma; Serafim, Teresa; Garrido, Jorge; Borges, Fernanda; Oliveira, Paulo. "Improvement of menadione cytotoxic potential by a mitochondria-targeted strategy.". Paper presented in MitoPorto: Advances in Mitochondrial Research International Symposium, University of Porto, Portugal, 2017.
  33. Costa, Cláudio; Maleita, Joana; Deus, Cláudia M.; Pereira, Susana P; Serafim, Teresa; Sardão, Vilma; Oliveira, Paulo; Cunha-Oliveira, Teresa. "Characterization of mitochondrial parameters in cell lines in the presence or absence of glucose. Bioenergetic Analysis: establishment and characterization of new models.". Paper presented in MitoPorto - Advances in Mitochondrial Research, University of Porto, Portugal,, 2017.
  34. Serafim, Teresa; Pinho, Sónia; Martins, Tatiana R; Sardão, Vilma; Grilo, Luís F.; Cavallaro, Chiara H.; Yang, Shanshan; et al. "Impact of Maternal Obesity During Pregnancy on Fetal Hepatic Redox Profile and Quality Control Proteins.". Paper presented in MitoPorto - Advances in Mitochondrial Research, Porto, Portugal. University of Porto, Portugal, 2017.
  35. Serafim, Teresa; Deus, Cláudia M.; Cunha-Oliveira, Teresa; Sardão, Vilma; Cunha, Pedro; Veloso, Caroline; Costa, Daniela; et al. "Stimulation of mitochondrial metabolism in human breast cancer cells results in increased cell motility and decreased resistance to metabolic inhibitors.". Paper presented in MitoPorto - Advances in mitochondrial research, International Symposium, Porto, University of Porto, Portugal, 2017.
  36. Campos, J.; Pereira, Francisco; Costa, Ernesto; Sardão, Vilma; Cunha-Oliveira, Teresa; Silva, T.B.; Simões, Rui F.; et al. "Extracting Knowledge from Data to Predict Mitochondrial Toxicity Indexes for Pharmacological Compounds". Paper presented in MitoPorto - Advances in mitochondrial research. International symposium, 2017.
  37. Sardão, Vilma; Silva, T.B.; Simões, Rui F.; Oliveira, Paulo; Veloso, Caroline; Valente, M.J.; Silva, R.S.; et al. "Parkinson¿s disease therapy with improved Catechol O-Methyltransferase (COMT) inhibitors display lower mitochondrial liabilitie". Paper presented in MitoPorto - Advances in mitochondrial research. International symposium, 2017.
  38. Gomes, Cátia; Teixeira, José; Oliveira, Paulo J.; Ferreira, Isabel C. F. R.; Ramalho-Santos, João; Azul, Anabela Marisa. "Effects of edible mushroom extracts on palmitic acid-induced lipotoxicity in human HepG2 cells". Paper presented in MitoPorto - Advances in Mitochondrial Research: https://sites.google.com/site/mitoporto2018/, 2017.
  39. Bento, Guida; Oliveira, Paulo; Sardão, Vilma. "A Protocol for Human Urine-derived Stem Cells Isolation, Expansion, and Mitochondrial Function Profile Analysis.". Paper presented in 51th Annual Meeting of the European Society for Clinical Investigation, Genoa, Italy, 2017.
  40. Sardão, Vilma; Silva, Tiago B.,; Simões, Rui; Oliveira, Paulo; Vamente, Maria J.; Silva, Renata S.; Remião, Fernando; Borges, Fernanda. "Developing a Novel Generation of Catechol O-Methyltransferase (COMT) Inhibitors Without Mitochondrial Liabilities for the Therapy of Parkinson¿s Disase". Paper presented in 7th World Congress on Tergeting Mitochondria, 2016.
  41. André, Ferreira; Simões, Rui F.; Vilaça, A.; Carvalho, F.S.; Garcia, R.; Burgeiro, Ana; Cunha-Oliveira, Teresa; Oliveira, Paulo. "Decreased global DNA methylation levels and gene expression patterns related metabolic end epigenetic remodeling enzymes are observed after Doxorubicin sub-chronic treatment". Paper presented in 50th Annual Scientific Meeting of the European Society for Clinical Investigation, 2016.
  42. Serafim, Teresa; Teresa Cunha-Oliveira; Sardão, Vilma; Deus, Cláudia M.; Greene, Amy; Perkins, Edward; Oliveira, Paulo. "Characterization of Mitochondria of Breast Cancer Cell Lines.". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  43. Branco, Ana F.; Sampaio, Susana F.; Sardão, Vilma; Gonzales, Susana; Oliveira, Paulo. "Isoproterenol-induced toxicity on H9c2 myoblasts depends on the differentiation status". Paper presented in 47th Annual Meeting of the European Society for Clinical Investigation, Albufeira, Portugal April 17-20, 2013, 2013.
  44. Serafim, Teresa; Sardão, Vilma; Greene, Amy; Perkins, Edward; Santos, Maria S.; Oliveira, Paulo. "Profilling mitochondrial physiology in commercial human cancer cell line for evaluating coumpound anticancer activity". Paper presented in 47th Annual Meeting of the European Society for Clinical Investigation, Albufeira, Portugal, 2013.
  45. Sampaio, Susana; Moreira, Ana C.; Branco, Ana; Santos, Maria S.; Oliveira, Paulo; Sardão, Vilma. "Apoptosis-inducing Factor (AIF) Role in Anthracycline-Induced Cardiomyoblast Cell Death". Paper presented in OCC conferences: Oxidants and Antioxidants in Biology ¿ Cell Signaling and Nutrient-Gene Interactions, Alba, Italy,, 2012.
  46. Sampaio, Susana; Moreira, Ana C.; Santos, Maria S.; Oliveira, Paulo; Sardão, Vilma. "Role of the Apoptosis-inducing Factor (AIF) on Doxorubicin-induced Cardiomyoblast Cell Death". Paper presented in 6th National Meeting on Cell Signaling, Braga, Portugal, 2012.
  47. Silva, Ana M.; Oliveira, Paulo; Moreira, Ana C.; Santos, Maria S.; Sardão, Vilma. "Are phytoestrogens able to prevent lipotoxicity in cardiac cells?". Paper presented in 46th Annual Scientific Meeting of the European Society for Clinical Investigation, Budapest, Hungary, 2012.
  48. Serafim, Teresa; Sardão, Vilma; Greene, Amy; Perkins, Edward; Santos, Maria S.; Oliveira, Paulo. "Mitochondrial characterization of breast cancer cell lines for chemotherapeutic in vitro studies.". Paper presented in AACR Special Conference: Metabolism and Cancer, Baltimore, USA, 2011.
  49. Moreira, Ana C.; Branco, Ana F.; Oliveira, Paulo; Sardão, Vilma. "Caspase-independent apoptosis induced by Doxorubicin on Embryonic Ventricular H9c2 Myoblasts ¿ Role of Apoptosis Inducing Factor (AIF) and Endonuclease G". Paper presented in 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy, 2010.
  50. Gonçalves, Inês; Carneiro, D.; Lumini-Oliveira, José; Machado, Nuno; Marques, F.; Sardão, Vilma; Oliveira, Paulo; Magalhães, José; Ascensão, António. "Effects of acute endurance exercise on heart and liver mitochondrial function in rats treated with Doxorubicin". Paper presented in 3rd Meeting of Young Researchers of University of Porto, Porto, Portugal, 2010.
  51. Branco, Ana F.; Moreira, Ana C.; Pereira, Susana P; Sardão, Vilma; Oliveira, Paulo. "Toxicity of Isoproterenol Increases with the Differentiation State of H9c2 Myoblasts". Paper presented in 49th ASCB Annual Meeting, San Diego, CA, USA, 2009.
  52. Braga, Teresa M.; Marques, J.; Almeida Paz, Filipe A.; Pillinger, M.; Branco, A.F.; Sardão, Vilma; Diogo, C.V.; et al. "Nano-encapsulation of Antitumoral Metal Drug Candidates using Cyclodextrins". Paper presented in Nanomedicine 2009 ¿ 2nd European Summer School in Nanomedicine, 2009.
  53. Branco, Ana F.; Moreira, Ana C.; Holy, Jon; Wallace, Kendall B.; Oliveira, Paulo; Sardão, Vilma. "Differential Sensitivity of Undifferentiated and Differentiated H9c2 Myoblasts to the Cardiotoxicant Doxorubicin". Paper presented in Molecular Regulation of Cardiac Disease Symposium, London, UK,, 2009.
  54. Serafim, Teresa; Sardão, Vilma; Matos, Júlio A.; Pereira, Gonçalo C.; Branco, Ana F.; Pereira, Sandro L.; Parke, Donna; et al. "Sanguinarine Inhibits the Proliferation of Metastatic Melanoma Cells by Nuclear and Mitochondrial Effects". Paper presented in Chemistry in Cancer Research: A Vital Partnership in Cancer Drug Discovery and Development, New Orleans, Louisiana, USA, 2009.
  55. Gonçalo C. Pereira; Susana P. Pereira; Maria S. Santos; António J. Moreno; Paulo J. Oliveira; Pereira, Goncalo C.; Pereira, Susana S.; et al. "Cardiac, Hepatic and Renal Mitochondrial Toxicity of Doxorubicin in a Sub-chronic in vivo Model". Paper presented in United Mitochondrial Disease Foundation – Mitochondrial Medicine 2009, 2009.
    10.1016/j.mito.2009.12.086
  56. Silva, Filomena S.G.; Sardão, Vilma; Oliveira, Paulo; Santos, Maria S.; Sousa, Maria do Céu; Santos-Silva, Alice; Pereira, Petronila Rocha. "Effects of 13-cis-RA and acitretin on tumor cell proliferation and isolated liver mitochondria". Paper presented in 16th National Congress of Biochemistry, Ponta Delgada, São Miguel, Açores, Portugal, 2008.
  57. Silva, João P.; Sardão, Vilma; Proença, Fernanda; Coutinho, Olga P.; Oliveira, Paulo. "Nitrogen compounds as protectors of oxidative damage induced in H9c2 myoblasts". Paper presented in 16th Euroconference on Apoptosis & 5th Swiss Apoptosis Meeting, Bern, Switzerland,, 2008.
  58. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Doxorubicin Toxicity in H9c2 Embryonic Cardiomyoblasts: Morphological Alterations and Activation of p53-Bax Signaling Pathway". Paper presented in 6th Annual meeting of the Society for Heart and Vascular Metabolism, Boston, Massachusetts, USA, 2008.
  59. Branco, Ana F.; Sardão, Vilma; Pereira, Sandro L.; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.; Oliveira, Paulo. "Differentiation of H9c2 embrionic ventricular cells results into increased susceptibility to the cardiac toxicants dosorubicin and isoproterenol". Paper presented in 6th Annual meeting of the Society for Heart and Vascular Metabolism, Boston, Massachusetts, USA, 2008.
  60. Amaral, Sandra; Mota, Paula C; Lacerda, Beatriz; Oliveira, Paulo; Ramalho-Santos, João; Martins, Luís. "Mitochondrial testicular function: effects of age". Paper presented in 15th European testis workshop (Naantali, Finland), 2008.
  61. Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João. "Characterization of mitochondrial bioenergetics of cat testicular cells: variations with age and other functions". Paper presented in 15th European testis workshop" ( Naantali, Finland), 2008.
  62. Pereira, Sandro L.; Sardão, Vilma; Branco, Ana F.; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.; Oliveira, Paulo. "Toxicity of Doxorubicin and Isoproterenol Depends on the Differentiation Stage of H9c2 Myoblasts". Paper presented in Society of Toxicology Annual Meeting 2008, Seattle, WA, EUA, 2008.
  63. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Doxorubicin induces Apoptosis in H9c2 myoblasts ¿ Contribution of P53/Bax pathways and oxidative stress". Paper presented in Apoptosis World 2008, From Mechanisms to Applications, Luxembourg, 2008.
  64. Branco, Ana F.; Pereira, Sandro L.; Sardão, Vilma; Wallace, Kendall B.; Oliveira, Paulo. "Apoptotic effect of isoproterenolon H9c2 myoblasts: Relevance of differentiation State". Paper presented in Apoptosis World 2008, From Mechanisms to Applications, Luxembourg,, 2008.
  65. Serafim, Teresa; Sardão, Vilma; Carvalho, Filipa S.; Marques, Maria P.; Garrido, Jorge; Milhazes, Nuno; Borges, Fernanda; et al. "Antiproliferative activity of ferulic and caffeic acid derivatives on tumor cell lines ¿ Structure-function relations and direct effects on mitochondria". Paper presented in Apoptosis World 2008, From Mechanisms to Applications, Luxembourg, 2008.
  66. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Morphological Hallmarks of Doxorubicin Toxicity on H9c2 Myoblasts: The pro-oxidant action of the antineoplastic agent". Paper presented in European Meeting of the Society for Free Radical Research, Vilamoura, Portugal, 2007.
  67. Braga, Susana S.; Mokal, Vijaya; Paz, Filipe A. A.; Marques, Maria P. M.; Branco, Ana F.; Sardão, Vilma; Oliveira, Paulo; et al. "Cyclodextrin encapsulation of biomimetic organometallic cancer drud candidates". Paper presented in 6th International Medicinal Chemistry Symposium, Istanbul, Turkey, 2007.
  68. Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João. "Characterization of the mitochondrial membrane potential in domestic cat testicular cells: possible implications for germ cell function". Paper presented in 40th Annual Meeting of the Society for the Study of Reproduction¿ (San Antonio, Texas, USA), 2007.
  69. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Morphologic Alterations Induced by the Antineoplastic Agent Doxorubicin in H9c2 myoblasts: Relevance for Doxorubicin Cardiotoxicity". Paper presented in First Iberic Meeting on Medicinal Chemistry ¿ Anticancer Agents, Regua, Portugal, 2007.
  70. Serafim, Teresa; Sardão, Vilma; Holy, Jon; Marques, Maria P.; Batista de Carvalho, Luís A.E.; Garrido, Jorge; Milhazes, Nuno; et al. "Anti-proliferative profile of potential lipophilic antioxidants structurally based on the dietary antioxidants ferulic and caffeic acids". Paper presented in First Iberic Meeting on Medicinal Chemistry ¿ Anticancer Agents, Regua, Portugal, 2007.
  71. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "The H9c2 cell Line as a Model for Cardiotoxicology Studies ¿ Imaging of Cell Dysfunction Induced By Tert-Butylhydroperoxide". Paper presented in XV National Congress of Biochemistry, Aveiro, Portugal, 2006.
  72. Pereira, Gonçalo C.; Serafim, Teresa; Sardão, Vilma; Teles, Ana I.; Moreno, António J. M.; Parke, Donna; Perkins, Edward; Holy, Jon; Oliveira, Paulo. "Berberine-induced Mitochondrial Depolarization and Fragmentation in K1735-M2 Rat Melanoma Cells ¿ A Possible Mechanism for Berberine Anti-proliferative / Pro-apoptotic actions". Paper presented in XV National Congress of Biochemistry, Aveiro, Portugal, 2006.
  73. Matos, Júlio A.; Serafim, Teresa; Sardão, Vilma; Branco, Ana F.; Moreno, António J. M.; Parke, Donna; Perkins, Edward; Holy, Jon; Oliveira, Paulo. "Mitochondrial Involvement in Sanguinarine-Induced Apoptosis". Paper presented in XV National Congress of Biochemistry, Aveiro, Portugal, 2006.
  74. Marques, Maria P.; Amado, A.M.; Fiuza, S.M.; Oliveira, Paulo; Sardão, Vilma; Soares, Ana S; Urbano, Ana M.; Batista De Carvalho, L.A.E.. "Polynuclear Pt(II) and Pd(II) Polyamine Complexes as Novel Anticancer Agents,". Paper presented in XXXVII Meeting of Portuguese Society of Pharmacology, 2006, Porto, Portugal, 2006.
  75. Moreira, Ana C.; Branco, Ana F.; Holy, Jon; Oliveira, Paulo; Santos, Maria S.; Sardão, Vilma. "Role of the Apoptosis Inducing Factor and Endonuclease G in the Cytotoxicity of Doxorubicin on Embryonic Ventricular H9c2 cells". Paper presented in 7th Annual meeting of the Society for Heart and Vascular Metabolism, Padova, Italy, 2006.
  76. Fiuza, Sónia; Amado, Ana M; Oliveira, Paulo; Sardão, Vilma; Marques, Maria P.; Batista de Carvalho, Luís A.E.. "Pt(II) and Pd(II) Complexes with Biogenic Amines - Structure-Activity Study". Paper presented in First European Conference on Chemistry for Life Sciences. Rimini, Italy, 2005.
  77. Fiuza, Sónia; Amado, Ana M.; Oliveira, Paulo; Sardão, Vilma; Marques, Maria P.; Batista de Carvalho, Luis A.E.. "Structure-Activity Study of Pt(II) and Pd(II) Spermidine Complexes". Paper presented in 12th International Conference on Biological Inorganic Chemistry - ICBIC12, Ann Arbor, Michigan, USA, 2005.
  78. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; Moreno, Antonio J. M.. "Caffeine Induces Cytochrome c Release and Reduces Cardiac Mitochondrial ATP Production". Paper presented in XXIV Congresso Portugues de Cardiologia , Madeira (Portugal), 2003.
  79. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Moreno, António J. M.. "Toxicity of Caffeine in Heart Mitochondria: Enhancement of Permeability Transition and Disturbance of Mitochondrial Bioenergetic Processes". Paper presented in XIII Congresso Português de Bioquímica, Lisboa (Portugal), 2002.
  80. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; Moreno, António J. M.. "Mitocôndrias Cardíacas e Cafeína ¿ Desregulação da Homeostase do Cálcio e Interacções com Cadeia Respiratória". Paper presented in XXIII Congresso Português de Cardiologia, Vilamoura, Portugal, 2002.
  81. Oliveira, Paulo; Rolo, Anabela P.; Coxito, Pedro; Santos, Dario L.; Sardão, Vilma; Seiça, Raquel; Monteiro, Pedro; et al. "Mitochondria From Diabetic Rats Cardiomyocytes are more resistent to the Induction of Permeability Transition Pore". Paper presented in 2nd European Meeting on Vascular Biology and Medicine, ULM, German, 2001.
  82. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; Moreno, António J. M.. "Caffeine Induces Directly the Permeability Transition in Isolated Rat Heart Mitochondria". Paper presented in XXII Congresso Português de Cardiologia, Vilamoura, Portugal, 2001.
  83. Oliveira, Paulo; Rolo, Anabela P.; Seiça, Raquel; Sardão, Vilma; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; et al. "Heart Mitochondria From Diabetic Rats Are More Resistant to the Induction of the Mitochondrial Permeability Transition". Paper presented in XXII Congresso Português de Cardiologia, Vilamoura, Portugal, 2001.
Encyclopedia entry
  1. Marques, Mário P.; Mendonça, Laura; Neves, Beatriz G.; Varela, Carla; Oliveira, Paulo; Cabral, Célia. "Pharmacological Wound Healing Evidence of Iberian Lamiaceae". In Scholarly Community Encyclopedia, 2023. https://encyclopedia.pub/entry/41740.
    Published
Journal article
  1. Ferreiro, Elisabete; Monteiro, Mariana; Pereira, Francisco; Barroso, Cristina; Egas, Conceição; Macedo, Paula; Valero, Jorge; Sardão, Vilma A.; Oliveira, Paulo J.. "Age-dependent energy metabolism and transcriptome changes in urine-derived stem cells". Mechanisms of Ageing and Development 218 (2024): 111912. http://dx.doi.org/10.1016/j.mad.2024.111912.
    10.1016/j.mad.2024.111912
  2. Amorim, Ricardo; Magalhães, Carina C.; Benfeito, Sofia; Cagide, Fernando; Tavares, Ludgero C.; Santos, Katia; Sardão, Vilma A.; et al. "Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism". Biochemical Pharmacology 219 (2024): 115953. http://dx.doi.org/10.1016/j.bcp.2023.115953.
    10.1016/j.bcp.2023.115953
  3. Amorim, Ricardo; Chavarria, Daniel; Soares, Pedro; Benfeito, Sofia; Cagide, Fernando; Teixeira, José; Oliveira, Paulo; Borges, Fernanda. "Decreasing the Burden of Non-Alcoholic Fatty Liver Disease: from Therapeutic Targets to Drug Discovery Opportunities". Medicinal Research Reviews (2024):
    Submitted
  4. Aryane Cruz Oliveira Pinho; Diana Santos; Paulo J. Oliveira; Ermelindo Carreira Leal; Eugenia Carvalho. "Real-time OXPHOS capacity analysis in wounded skin from diabetic mice: A pilot study". European Journal of Clinical Investigation (2023): https://doi.org/10.1111/eci.14128.
    10.1111/eci.14128
  5. Elsa T. Rodrigues; Eduarda Pereira; Paulo J. Oliveira; Miguel A. Pardal; Rodrigues, Elsa T.; Pereira, Eduarda; Oliveira, Paulo J.; Pardal, Miguel A.. "The H9c2(2-1) cell-based sulforhodamine B assay is a non-animal alternative to evaluate municipal wastewater quality over time". Environmental Monitoring and Assessment 195 11 (2023): https://doi.org/10.1007/s10661-023-12017-8.
    10.1007/s10661-023-12017-8
  6. Cavaleiro, Carla; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Valero, Jorge; Mota, Sandra I.; Ferreiro, Elisabete. "Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions". Frontiers in Molecular Neuroscience 16 (2023): http://dx.doi.org/10.3389/fnmol.2023.1229728.
    10.3389/fnmol.2023.1229728
  7. Pereira, Susana P.; Diniz, Mariana S.; Tavares, Ludgero C.; Cunha-Oliveira, Teresa; Li, Cun; Cox, Laura A.; Nijland, Mark J.; Nathanielsz, Peter W.; Oliveira, Paulo J.. "Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model". International Journal of Molecular Sciences 24 20 (2023): 15192. http://dx.doi.org/10.3390/ijms242015192.
    10.3390/ijms242015192
  8. Luís F. Grilo; João D. Martins; Mariana S. Diniz; Carolina Tocantins; Chiara H. Cavallaro; Inês Baldeiras; Teresa Cunha-Oliveira; et al. "Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress". Clinical Science 137 17 (2023): 1347-1372. https://doi.org/10.1042/CS20230048.
    10.1042/CS20230048
  9. Monteiro-Alfredo, Tamaeh; dos Santos, Jéssica Maurino; Antunes, Kátia Ávila; Cunha, Janielle; da Silva Baldivia, Debora; Pires, Ana Salomé; Marques, Inês; et al. "Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer activity". Frontiers in Pharmacology 14 (2023): http://dx.doi.org/10.3389/fphar.2023.1223933.
    10.3389/fphar.2023.1223933
  10. Tocantins, Carolina; Martins, João D.; Rodrigues, Óscar M.; Grilo, Luís F.; Diniz, Mariana S.; Stevanovic-Silva, Jelena; Beleza, Jorge; et al. "Metabolic mitochondrial alterations prevail in the female rat heart 8¿weeks after exercise cessation". European Journal of Clinical Investigation 53 11 (2023): http://dx.doi.org/10.1111/eci.14069.
    10.1111/eci.14069
  11. Quatorze, Marta; Silva, Filomena; Duarte, Ana I.; Cardoso, João; Caetano, Carolina; Ramalho-Santos, João; Oliveira, Paulo J.; Amaral, Sara Varela. "Amyotrophic Lateral Sclerosis: When Nerve Cells Run Out of Power". Frontiers for Young Minds 11 (2023): http://dx.doi.org/10.3389/frym.2023.974736.
    Published • 10.3389/frym.2023.974736
  12. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "Reply to the Comment on “1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis”". Pharmacological Research 191 (2023): 106623. http://dx.doi.org/10.1016/j.phrs.2022.106623.
    Published • 10.1016/j.phrs.2022.106623
  13. Amorim, Ricardo; Magalhães, Carina C.; Borges, Fernanda; Oliveira, Paulo J.; Teixeira, José. Corresponding author: Amorim, Ricardo. "From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria". Biology 12 4 (2023): 595. http://dx.doi.org/10.3390/biology12040595.
    10.3390/biology12040595
  14. Bessa, Cláudia; Loureiro, Joana B.; Barros, Matilde; Isca, Vera M. S.; Sardão, Vilma A.; Oliveira, Paulo J.; Bernardino, Raquel L.; et al. "Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCd Activator". International Journal of Molecular Sciences 24 6 (2023): 5710. http://dx.doi.org/10.3390/ijms24065710.
    10.3390/ijms24065710
  15. Diana Sousa; Mariana Rocha; Andreia Marreiros Amaro; Marcos Divino Ferreira-Junior; Keilah Valéria Naves Cavalcante; Tamaeh Monteiro-Alfredo; Tamaeh Monteiro Alfredo; Cátia Barra; et al. "Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models". Nutrients (2023): https://www.mdpi.com/2072-6643/15/5/1281.
    10.3390/nu15051281
  16. Mário P. Marques; Laura Mendonça; Beatriz G. Neves; Carla Varela; Paulo Oliveira; Célia Cabral. "Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing". Pharmaceuticals (2023): https://doi.org/10.3390/ph16030347.
    10.3390/ph16030347
  17. Sofia Benfeito; Carlos Fernandes; Daniel Chavarria; Sandra Barreiro; Fernando Cagide; Lisa Sequeira; José Teixeira; et al. "Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks". Journal of Medicinal Chemistry (2023): https://doi.org/10.1021/acs.jmedchem.2c01630.
    10.1021/acs.jmedchem.2c01630
  18. José P. Castelão-Baptista; Sara Valente; Sara Canário; David Oppolzer; A.I.R.N.A.Barros; Carlos Venâncio; Tânia Martins; et al. "Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity". Nutrients (2023): https://www.mdpi.com/2072-6643/15/4/924.
    10.3390/nu15040924
  19. Inês Ramos Rego; Daniela Silverio; Maria Isabel Eufrásio; Sandra Sofia Pinhanços; Bruna Lopes da Costa; José Carlos Santos Teixeira; Hugo Fernandes; et al. "TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status". Antioxidants (2023): https://www.mdpi.com/2076-3921/12/2/381.
    10.3390/antiox12020381
  20. Jelena Stevanovic-Silva; Jorge Beleza; Pedro Coxito; Paulo J. Oliveira; António Ascensão; José Magalhães. "Gestational Exercise Antagonises the Impact of Maternal High-Fat High-Sucrose Diet on Liver Mitochondrial Alterations and Quality Control Signalling in Male Offspring". International Journal of Environmental Research and Public Health (2023): https://doi.org/10.3390/ijerph20021388.
    10.3390/ijerph20021388
  21. Chouvarine, Philippe; Hysko, Klea; Chan, Stephen Y.; Oliveira, Paulo; Maron, Bradley A.; Kourembanas, Stella; Hansmann, Georg. "Second International Pulmonary Hypertension/Heart Failure Symposium—Structural heart disease, right ventricular dysfunction, and stem cell therapy: The European Pediatric Pulmonary Vascular Disease Network". Pulmonary Circulation 13 1 (2023): http://dx.doi.org/10.1002/pul2.12175.
    10.1002/pul2.12175
  22. Soares, Pedro; Chavarria, Daniel; Silva, Catia; Silva, Filomena S.G.; Oliveira, Paulo J.; Borges, Fernanda. "Drug discovery and amyotrophic lateral sclerosis: Emerging challenges and therapeutic opportunities". Ageing Research Reviews 83 (2023): 101790. http://dx.doi.org/10.1016/j.arr.2022.101790.
    10.1016/j.arr.2022.101790
  23. Diniz, Mariana S; Hiden, Ursula; Falcão-Pires, Inês; Oliveira, Paulo J; Sobrevia, Luis; Pereira, Susana P; Diniz, Mariana S.; Oliveira, Paulo J.; Pereira, Susana P.. "Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869 8 (2023): 166834. http://hdl.handle.net/10316/108720.
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    Submitted
  25. Monteiro-Alfredo, Tamaeh; dos Santos, Jessica Maurino; Antunes, Katia Avila; Cunha, Janielle; Baldivia, Debora da Silva; Pires, Ana Salome; Marques, Ines; et al. "Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer activity". Frontiers in Pharmacology (2023): https://publons.com/wos-op/publon/61325685/.
    10.3389/FPHAR.2023.1223933
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  28. Carlos Fernandes; Fernando Cagide; Jorge Simões; Carlos Pita; Eurico Pereira; Afonso J. C. Videira; Pedro Soares; et al. "Targeting Hydroxybenzoic Acids to Mitochondria as a Strategy to Delay Skin Ageing: An In Vitro Approach". Molecules (2022): https://doi.org/10.3390/molecules27196183.
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  29. Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al. "Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems". Redox Biology 55 (2022): 102400. http://dx.doi.org/10.1016/j.redox.2022.102400.
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  30. Emiliano Panieri; Sónia A. Pinho; Gonçalo J. M. Afonso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Luciano Saso. "NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells". Cells (2022): https://doi.org/10.3390/cells11152401.
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Preprint
  1. Grilo, Luís F.; Zimmerman, Kip D.; Puppala, Sobha; Chan, Jeannie; Huber, Hillary F.; Li, Ge; Jadhav, Avinash Y. L.; et al. "Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway". 2023. http://dx.doi.org/10.1101/2023.11.17.567640.
    10.1101/2023.11.17.567640
  2. Teresa Cunha-Oliveira; Daniela Franco Silva; Luis Segura; Inês Baldeiras; Ricardo Marques; Tatiana Rosenstock; Paulo J. Oliveira; Filomena S.G. Silva. "Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations". 2022. https://doi.org/10.1101/2022.03.03.482309.
    10.1101/2022.03.03.482309

Intellectual property

Patent
  1. Borges, Maria Fernanda; Oliveira, Paulo; Teixeira, José; Cagide-Fagin, Fernando; Oliveira, Ana Catarina. 2018. "HYDROXYBENZOIC DERIVATIVES, METHODS AND USES THEREOF".
  2. Oliveira, Paulo; Teixeira, José; Cagide-Fagin, Fernando; Benfeito, Ester Sofia. 2018. "HYDROXYCINNAMIC DERIVATIVES, METHODS AND USES THEREOF (".

Other

Other output
  1. Synthesis, Characterisation and Antiproliferative Studies of Allyl(dicarbonyl)(cyclopentadienyl)molybdenum Complexes and Cyclodextrin Inclusion Compounds. The complexes [(eta(5)-C5H4-CO-R)Mo(CO)(2)(eta(3)-C3H5)] [R = OH (1), Phe OMe (2)] have been examined as guests for the cyclodextrin (CD) hosts beta-CD and heptakis(2,3,6-tri-O-methyl)-beta-CD (TRIMEB), and the resultant inclusion compounds have been characterised in the solid state by elemental and thermogravimetric analyses, powder X-ray diffraction, C-13{H-1) cross-polarisation (CP) magic angle. 2014. Braga, Susana S.; Mokal, Vijaya; Almeida Paz, Filipe A.; Pillinger, Martyn; Branco, Ana F.; Sardao, Vilma A.; Diogo, Catia V.; et al. http://hdl.handle.net/10773/19837.
    10.1002/ejic.201402540
  2. Mentha aquatica L. extract affects mitochondrial bioenergetics. 2013. Ferreira, Fernanda M.; Pereira, Olívia R.; Cardoso, Susana M.; Oliveira, Paulo J.; Moreno, António J.M.. http://hdl.handle.net/10198/8394.
  3. Bile acids are toxic for isolated cardiac mitochondria. Abstract Cholestasis and other liver diseases may affect the heart through the toxic effects of the retained bile acids on cardiac mitochondria, which could explain the origin of hepatic-derived cardiomyopathies. The objective of this work was to test the hypothesis that bile acids are toxic to heart mitochondria for concentrations that are relevant for cholestasis. Heart mitochondria were isolate. 2005. Ferreira, Manuela; Coxito, Pedro; Sardão, Vilma; Palmeira, Carlos; Oliveira, Paulo. http://hdl.handle.net/10316/7824.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/12/02 A Story of Bad Livers Valorizebyproducts Webinars
Universidade de Trás-os-Montes e Alto Douro (Online, Portugal)
2021/10/29 A Mitochondria-Targeted Caffeic Acid Derivative Reverts Cellular and Mitochondrial Defects in Human Skin Fibroblasts from Male Sporadic Parkinson’s Disease Patients Targeting Mitochondria Meeting
World Mitochondria Society (online, Germany)
2021/06/09 Mitochondrial Determinants of Doxorubicin Cardiotoxicity 55th Annual meeting of the European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease”
European Society for Clinical Investigation (Online, Italy)
2021/05/07 Mitochondria as a Target in Drug Development First webinar on Medicinal Chemistry – Designing Tomorrow’s Therapeutics
online, organized by Dr. Fernanda Borges, University of Porto, Portugal (Online, Portugal)
2021/03/11 Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention Redox Webinar Series - Oxidative Stress: Biochemical and Pharmacological Aspects (online)
organized by Dr. Luciano Saso, Sapienza University of Rome, Italy (online, Italy)
2020/09/03 mtFOIE-GRAS Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease EuroScience Open Forum (ESOF)
(Trieste, Italy)
2020/02/18 FOIE GRAS or A Story of Mitochondria and Fatty Livers Escola Superior Agrária de Coimbra (ESAC)
(Coimbra, Portugal)
2019/11/30 The Cellular Chi: Mitochondria as a Target for Natural and Artificial Compounds in Health and Disease Sino-Portugal Forum on Traditional Medicine
(Nanchang, China)
2019/11/10 Over and Under-nutrition During Pregnancy as a Remodeling Factor for Liver and Heart Fetal Mitochondria International Workshop on Advances inAnalytical Methods for Monitoring Food Quality and Safety
(Bratislava, Slovakia)
2019/09/18 Mitochondria, pluripotency and quality control in embryonal carcinoma cells 6th Conference on Mitochondria, Apoptosis and Cancer (MAC2019), Prague, Czech Republic
(Praga, Czech Republic)
2019/09/06 Metabolism, Quality Control, and Pluripotency in Embryonal Carcinoma Cells II FEBS Advanced Course on Oncometabolism
(Luso, Portugal)
2019/07/16 MitoTAG: From Cellular Organelle to Idea to Start Up and Beyond EIT Health InnoStars Bootcamp
(Coimbra, Portugal)
2019/07/04 Improving Nature: Targeting Active Polyphenols to Mitochondria XIV Annual CICS-UBI Meeting
(Covilhã, Portugal)
2019/07/01 POWER-UP - Mitochondrial Biology and Follies, ETN Treatment Network School University of Coimbra
(Coimbra, Portugal)
2019/05/24 Disruption of Mitochondrial Metabolism and Circadian Genes by Anthracyclines 53rd Annual Meeting of the European Society for Clinical Investigation
(Coimbra, Portugal)
2019/03/30 From a small organelle to a small start-up and beyond…, Academica StartUC, University of Coimbra
(Coimbra, Portugal)
2019/03/29 In utero Programing of Mitochondrial Function by Nutrition TIFN Midterm Project Meeting
(Wageningen, Netherlands)
2019/03/16 From Mitochondria to Business. The Example of MitoTAG III Meet.Lab
(Coimbra, Portugal)
2019/01/17 Mitochondria as a Pharmacological and Toxicological Target in Drug Development International Iberian Nanothechnology Laboratory
(Braga, Portugal)
2019/01/17 MitoTAG: From Bench to Business International Iberian Nanothechnology Laboratory
(Porto, Portugal)
2018/11/23 Implications of Mitochondrial Metabolism for Aging Leonard Davies School of Gerontology, University of Southern California
(Califórnia, United States)
2018/07/29 MitoTAG EIT Health InnoStars Bootcamp
(Coimbra, Portugal)
2018/07/13 Pluripotency, mitochondrial metabolism, and quality control mechanisms in embryonal carcinoma cells MitoPORTO 2018
(Porto, Portugal)
2018/07/12 Identifying Mitochondrial Toxicity in Early Pre-Clinical Drug Development VIII Meeting of the Paul Ehrlich Euro-PhD Network
(Porto, Portugal)
2018/07/03 Understanding the Right and Wrong Metabolism in Lifestyle, Environment and Aging-related Diseases Encontro Ciência 2018
(Lisboa, Portugal)
2018/06/04 Malnutrition vs calorie restriction: The effects of maternal nutrient reduction in cardiac fetal mitochondrial function Bi-annual Meeting of the Society for Free Radical Research International
(Lisboa, Portugal)
2018/05/30 Back to the Basics: Evolution of Mitochondrial Respirometry and Basic Concepts 52nd Annual Meeting of the European Society for Clinical Investigation
(Barcelona, Spain)
2018/01/15 Metabolism and Pluripotency in Embryonal Carcinoma Stem Cells ICVS - Life and Health Sciences Research Institute
(Braga, Portugal)
2018/01/06 An Update on the ETN Project FOIE GRAS 52nd Annual Meeting of the European Society for Clinical Investigation
(Barcelona, Spain)
2017/12/21 Sirtuin 1-dependent Resveratrol Cytotoxicity and Pro-differentiation Activity on Breast Cancer Cells 2nd Biomedical Meeting at UC, University of Coimbra
(Coimbra, Portugal)
2017/12/08 Anthracycline-induced Cardiotoxicity: Tales from a Mitochondrial Journey Meet Your Future Workshop, Gottingen Medical Center
(Gottingen, Germany)
2017/11/21 Mitochondrial Alterations in Non-alcoholic Fatty Liver Disease: A Tale of (Bad) Nutrition and Batteries Science and Technology Week 2017, University of Trás-os-Montes and Alto Douro
(Vila Real, Portugal)
2017/09/22 Mitochondrial Toxicology in Drug Discovery and Development EpiChemBio (CM1406) and MuTaLig (CA15135) COST actions joint meeting 2017
(Porto, Portugal)
2017/09/19 Mitochondria vs. Godzilla: In Search of Energy Instituto Bissaya Barreto
(Coimbra, Portugal)
2017/09/16 Mitochondrial Metabolism and Cellular Quality Control Regulate Differentiation in P19 Embryonal Carcinoma Stem Cells Mitochondria, Apoptosis and Cancer, Bled
(Slovenia)
2017/06/18 Targeting Mitochondria in Cancer FEBS Advanced Course on Oncometabolism
(Figueira da Foz, Portugal)
2017/05/17 Targeting Mitochondria with Improved Dietary Antioxidants 51st Annual Meeting of the European Society for Clinical Investigation
(Genoa, Italy)
2017/05/17 ETN FOIE GRAS – the European Network 51st Annual Meeting of the European Society for Clinical Investigation
(Genoa, Italy)
2017/03/05 Mitochondrial Dysfunction and Bioenergetic Collapse ENEBT 2017 – National Meeting of Biotechnology Students, University of Aveiro
(Aveiro, Portugal)
2017/03/04 Mitochondria vs. Godzilla Electric Circuits, Disease and Smart Missiles IMeet.Lab, University of Coimbra
(Coimbra, Portugal)
2017/02/16 Optimizing Nature: Targeting Mitochondria with Enhanced Natural Antioxidants VIII Course Week, Agricultural School of Coimbra
(Coimbra, Portugal)
2016/12/28 Portugal, um País Apetecível? 5th GraPE Meeting, University of Coimbra
(Coimbra, Portugal)
2016/12/19 Heartbroken: Mitochondrial Damage by Anthracyclines I Biomedical Meeting @UC, University of Coimbra
(Coimbra, Portugal)
2016/11/02 Mitochondrial Folies: From Basic Science to Product Development Innovation Now 2016!
(Aveiro, Portugal)
2016/10/24 Optimizing Nature: Targeting Mitochondria with Enhanced Natural Antioxidants Targeting Mitochondria
(Berlim, Germany)
2016/10/19 Mitochondrial Remodeling During Embryonal Carcinoma Stem Cell Differentiation CEDOC, Universidade NOVA de Lisboa
2016/06/29 Polyphenol toxicity and mitochondrial function: an emergent link Porto Polyphenols Congress 2016
(Porto, Portugal)
2016/04/28 Mitochondrial TRAP1 in cancer metabolism and quality control 50th Annual Scientific Meeting of the European Society of Clinical Investigation
(Paris, France)
2016/03/21 Remodeling Mitochondria During P19 Embryonal Carcinoma Cell Differentiation IX National Meeting of the Biochemistry Students
(Coimbra, Portugal)
2015/10/08 Remodeling Mitochondria During P19 Embryonal Carcinoma Cell Differentiation Institute of Biotechnology CAS
(Prague, Czech Republic)
2015/05/30 Anthracycline-induced Cardiac Mitochondrial Injury: Multiple Targets, Multiple Effects 49th Annual Scientific Meeting of the European Society of Clinical Investigation
(Cluj, Romania)
2015/05/29 Exercising Mitochondria: Improving Mitochondrial Capacity by Physical Activity 49th Annual Scientific Meeting of the European Society of Clinical Investigation
(Cluj, Romania)
2015/05/07 Mitochondrial and Metabolic Remodeling During P19 Embryonal Carcinoma Cell Differentiation XXIII Porto Cancer Meeting
(Porto, Portugal)
2015/02/22 Mitochondrial Phenotype in Cancer Cells Give Science to Life Meeting
(Coimbra, Portugal)
2015/02/21 Targeting Mitochondria in Tumor Cells IN4Med Meeting
(Coimbra, Portugal)
2015/02/07 Basic mechanisms for Anthracycline cardiotoxicity and therapeutic targets Annual Meeting of the Study Group for Myocardium and Pericardium Diseases, Portuguese Cardiology Society
(Óbidos, Portugal)
2014/11/21 30. Cellular Respiration as a Biomarker: Evolution of Technology Integrating Biomarkers and Cell Physiology for Metabolic Profiling: Next Generation Approaches and Technologies Workshop, Biocant Park
(Cantanhede, Portugal)
2014/11/21 Analysis of Cell Metabolism Using the Seahorse Extracellular Flux Analyzer – Principles and Applications “Integrating Biomarkers and Cell Physiology for Metabolic Profiling: Next Generation Approaches and Technologies” Workshop, Biocant Park
(Cantanhede, Portugal)
2014/05/14 Mitochondrial Degeneration During Aging: Causes and Solutions 5th Symposium of Health Sciences “Aging”, Medical School, University of Lisbon
(Lisboa, Portugal)
2014/05/03 The Role of Mitochondria on Anthracycline-induced Cardiomyopathy 48th Annual Scientific Meeting of the European Society of Clinical Investigation
(Utrecht, Netherlands)
2014/04/28 Triterpenoid Derivatives as Mitochondrial Disturbing Agents in Breast Cancer Cell Lines Nencki Institute of Experimental Biology
(Varsóvia, Poland)
2013/07/09 Mitochondria as a Perfect Target in Health and Disease Department of Biology, University of Braga
(Braga, Portugal)
2013/06/11 Doxorubicin-induced Cardiac Mitochondrionopathy: A Tale of Targets and Mechanism CIAFEL, School of Sports and Physical Activity, University of Porto
(Porto, Portugal)
2013/04/29 Mitochondria as a Tool in Drug Discovery Natural Products: Health and Pharmaceutical Research Workshop, ESAC
(Coimbra, Portugal)
2013/04/17 Targeting the Powerplants in Cancer 47th Annual Meeting of the European Society for Clinical Investigation
(Albufeira, Portugal)
2013/01/27 In Vitro Models in Basic Research International Conference of Alternatives to Animal Experimentation
(Almada, Portugal)
2012/12/10 Alternatives to Animal Use in Toxicological Testing Alternatives to Animal Use in Pre-Clinical Studies, ShareBiotech
(Cantanhede, Portugal)
2012/11/25 Targeting Mitochondria in Cardiovascular Diseases and Cancer Jornadas de Bioquímica, University of Coimbra
(Coimbra, Portugal)
2012/11/08 19. Mitochondria as a Perfect Target in Health and Disease Targeting Mitochondria Meeting
(Berlim, Germany)
2012/10/25 Mitochondria and Polyphenols: a Tale of Mending Hearts Flawopiryna” Conference, Medical University of Lodz
(Lodz, Poland)
2012/07/10 Mitochondria as a Perfect Target in Health and Disease Department of Biology, University of Braga
(Braga, Portugal)
2012/03/31 Our Battery: What Keeps us Moving IEC, Institute for Education and Citizenship
(Mamarrosa, Portugal)
2012/03/29 Mitochondria in Health and Disease: a Tale of Injury and Redemption University of Tras-os-Montes and Alto Douro (UTAD)
(Vila Real, Portugal)
2012/03/24 Mitochondria: You Are what You Eat 45th Annual Scientific Meeting of the European Society for Clinical Research
(Budapeste, Hungary)
2012/03/23 Berberine as a Potential Mitochondrial-directed Anti-cancer Agent 45th Annual Scientific Meeting of the European Society for Clinical Investigation
(Budapeste, Hungary)
2012/02/22 Regulation of Mitochondrial Function by Exercise (joint research seminar/lecture for first year Medical Students) University of Valencia Medical School
(Valência, Spain)
2011/11/10 Mitochondrial Dynamics and Physiology During P19 Embryonal Cell Differentiation University of Texas Health Science Center, CPNR Research Seminar
(San Antonio, Texas, United States)
2011/11/09 Short-Circuit: Tales of Broken Mitochondria University of Texas Health Science Center Ob/Gyn Grand Rounds Seminar
(San Antonio, Texas, United States)
2011/06/08 Tales of Broken Mitochondria: Drug-induced Cardiac Mitochondrionopathy, World Pharma Congress
(Philadelphia, PA, United States)
2010/05/19 When Batteries Fail – Tales of Broken Mitochondria CNC Seminar
(Coimbra, Portugal)
2008/09/23 Anti-melanoma Effects of the Alkaloid Berberine - Role of Mitochondrial Interactions University of Minnesota
(Duluth, MN, United States)
2008/04/26 Mitochondrial Toxicology and Pharmacology V National Meeting of Biochemistry Students
(Coimbra, Portugal)
2006/11/03 Cardiac Mitochondrial Toxicity of Antineoplastic Agents 2006 CNC Seminars
(Coimbra, Portugal)
2005/09/08 Cardiac Mitochondrial Alterations During Doxorubicin Treatment: Targets and Preventive Strategies University of Colorado Health Sciences Center
(Denver, United States)
2003/11/26 Mitochondrial Permeability Transition – Relevance for Toxicity and Pathology Conferências de Bioquímica Vítor Madeira
(Coimbra, Portugal)
2002/09/10 Critical Role of Mitochondrial Protein Thiol Groups in the Inhibitory Action of Carvedilol on the Mitochondrial Permeability Transition 12th European Bioenergetics Conference (EBEC)
(Arcachon, France)
2002/03/20 Resistance to Myocardial Ischemia and Reperfusion – A Mitochondrial Determinant? V Congresso Português de Diabetes
(Vilamoura, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2017 - Current Mitochondria-directed Antioxidants as a Therapy for Non-Alcoholic Fatty Liver Disease
Supervisor
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016 - Current Urinary-derived Cells in Personalized Medicine: Role of Mitochondrial Metabolism
Supervisor
 Envelhecimento e Doenças Crónicas (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - Current Development of Multitarget Directed Antioxidants with Therapeutic Potential Towards Age-related Disorders
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - Current Role of Mitochondria in Drosophila Tissue Repair
Co-supervisor
 Envelhecimento e Doenças Crónicas (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 - Current An Innovative Metabolic and Epigenetic Engineering Approach to Reverse the Parkinson Disease Cell State
Supervisor
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015 - Current Neuroprotective Effects of Potent Antioxidant Molecules Isolated From Bifurcaria bifurcata and Codium tomentosum in an in vitro and in vivo Parkinson Disease Model
Co-supervisor
 Ciências Marinhas, Tecnologia e Gestão (PhD)
Instituto Politécnico de Leiria, Portugal
2012 - Current Menopause vs. Osteoporosis – The Role of Phytoestrogens on Bone Remodeling and their Antiosteoporetic Effects
Co-supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - Current Modulation of Heart and Skeletal Muscle Mitochondrial Sirtuin 3 by Acute Exercise and Endurance Training – Relevance for Exercise-induced Mitochondrial Adaptations
Supervisor
 Biociências
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022 - 2022 CardioCLOCK: Descoberta de Mecanismos de Interações entre Programação durante o Desenvolvimento e Envelhecimento do Coração / CardioCLOCK: Unraveling Mechanisms of Developmental Programming-aging interactions in the heart
Supervisor
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2022 - 2022 Organelle-targeted Radioconjugates for Auger Therapy of Prostate Cancer
Co-supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2020 Molecular Mechanims of Mitochondrial Transfer from Stromal cells to cancer cells with damaged mitochondrial DNA
Supervisor
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019 - 2019 Mitochondriotropic Antioxidants Based on Dietary Phenolic Acids as Modulators of Oxidative Stress on Skin Fibroblasts
Supervisor
 Biotecnologia Farmacêutica (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2019 MitoBULLET: Antioxidant Targeting of Mitochondria to Prevent Non-Alcoholic Fatty Liver Disease-induced Oxidative Stress
Supervisor
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019 - 2019 Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders.
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2019 Role of Mitochondria-Targeted Novel Antioxidants based in Dietary Polyphenols
Supervisor
 Biotecnologia Farmacêutica (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2015 - 2019 Targeting Hsp70 in Huntington's Disease
Co-supervisor
 Ciências Farmacêuticas
Universidade do Porto, Portugal
2014 - 2019 Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-epigenetics Link
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - 2018 Fetal Liver Mitochondria Alterations in an Ovine Model of Maternal Obesity
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016 - 2018 Fetal Liver Mitochondria Alterations in an Ovine Model of Maternal Obesity
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2018 Effect of Life-span Exercise Against Obesity-induced Brain Mitochondrial Dysfunction
Co-supervisor
 Metabolismo - Clínica e Experimentação (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2016 The role of mitochondria in Drosophila wound healing
Co-supervisor
 Envelhecimento e Doenças Crónicas (associação) (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - 2016 Targeting Dietary Antioxidants to Mitochondria: Regulating Mitochondrial Radical Production and Redox Signaling to Improve Human Health
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2016 Mechanisms of DNA Damage Detection and Repair in Embryonic Carcinoma Cells: A Model to Study Chemotherapy Resistance in Cancer Stem Cells
Co-supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2016 Programming of fetal cardio-renal mitochondria by maternal nutrition
Supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2015 Mitochondrial-directed antioxidants as anti-cancer agents
Co-supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2015 Doxorubicin cardiotoxicity: Metabolic landscaping of the epigenome
Co-supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2015 Mitochondria-directed Antioxidants as Anticancer Agents
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2015 Pathophysiology of Persistent Doxorubicin Cardiotoxicity: Metabolic Landscaping of the Epigenome
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2015 Role of Mitochondrial p66Shc in Nefazodone-induced Mitochondrial Toxicity on HepG2 Cells
Supervisor
 Biologia (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2011 - 2015 Unraveling Cancer Metabolism Through Flux Analysis and Metabolic Engineering
Co-supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2015 Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System – Impact of Different Doxorubicin Treatment Regimens
Supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014 Berberine modulation on doxorubicin-induced cell death and autophagy
Co-supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014 Cardiolipin content in P19 embryonal carcinoma cells
Co-supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014 Protection provided by phytoestrogens against cardiac lipotoxicity induced by palmitic acid
Co-supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014 Role of Sirtuin 3 on Doxorubicin-induced Toxicity on H9c2 Cardiomyoblasts
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014 Berberine Modulation on Doxorubicin-induced Cell Death and Autophagy
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014 Protection Provided by Phytoestrogens Against Cardiac Lipotoxicity Induced by Palmitic Acid
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014 Cardiolipin content in P19 embryonal carcinoma cells
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2014 TRAP1 Regulation of Mitochondrial Homeostasis and Cellular Quality Control
Supervisor
 Biologia (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2013 Oxidative Stress, Mitochondrial Dysfunction and Cellular pathology in Experimental Models of Hyperglycaemia and High Fat Diet
Supervisor
 Biologia (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2013 Idiosyncrasy of Drug-induced Mitochondrial Liabilities: From Mitochondrial DNA Single Nucleotide Polymorphisms to Mitochondrial Sirtuin
Supervisor
 Biologia (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013 A Metabolic Switch for Cell Differentiation
Co-supervisor
 Biologia (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013 Impact of H9c2 Cardiomyoblast Differentiation on Isoproterenol Toxicity: Different Modulation of Signaling Pathways
Supervisor
 Biologia
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013 A Lipidomics Approach to Hepatic Mitochondrial Function and Toxicology: Role of Diet-induced Modifications
Supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2012 Resveratrol and Cancer – What Role for Sirtuins?
Supervisor
 Biologia Aplicada (Master)
Universidade de Aveiro, Portugal
2010 - 2012 Role of p66Shc Signaling on Doxorubicin-induced Cardiac Mitochondrial Dysfunction
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2012 Mitochondrial Physiology During Doxorubicin-induced Selective Cardiotoxicity
Supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2011 Dimethylaminopyridine Derivatives of Lupane Triterpenoids Acting as Mitochondrial-directed Agents on Breast Cancer Cells
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2011 Mitochondria and Cancer: Opening Pandora’s Box
Supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2011 Apoptosis Signaling as a Therapeutic Target in Melanoma
Supervisor
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2006 - 2011 Mitochondrial Function and Cell Death in Cardioplegic Preserved Hearts: Effects of Ischemia and Ischemia and Ischemia/Reperfusion
Co-supervisor
 Bioquímica (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2009 Mitochondrial and Cellular Toxicity of Two Triterpenoid Derivatives
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2009 In Vivo Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Heart and Liver Mitochondrial Bioenergetics and ATP-sensitive Potassium Channels
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2009 Does Sub-Chronic Administration of Doxorubicin to Wistar Rats Result in Lung Apoptotic Signalling and Oxidative Stress?
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2008 Cellular Alterations Involved in the Different Susceptibility of Differentiated and Non-differentiated H9c2 Myoblasts to Doxorubicin
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2007 A Lipidomic Approach to Hepatic Mitochondrial Function and Toxicology: role of Diet-Induced Modifications
Co-supervisor
 Biociências (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/05/22 - 2019/05/24 Organizer of the 53rd Annual Meeting of the European Society for Clinical Investigation (2019/05/22 - 2019/05/24)
Seminar (Co-organisor)
 European Society for Clinical Investigation, Netherlands
2019/05/22 - 2019/05/24 Organization of Workshop “Mitochondrial Biology and Medicine”, part of the 53rd Annual Meeting of the European Society for Clinical Investigation (2019/05/22 - 2019/05/24)
Symposium (Co-organisor)
 European Society for Clinical Investigation, Netherlands
2018/10/23 - 2018/10/23 Organizer of Meeting “Mitochondrial DNA and Derived Peptides in Health and Disease” (2018/10/23 - 2018/10/23)
Seminar (Co-organisor)
 Universidade de Coimbra, Portugal
2018/05/30 - 2018/06/01 Organization of Workshop “Mitochondrial Biology and Medicine”, part of the 52rd Annual Meeting of the European Society of Clinical Investigation (2018/05/30 - 2018/06/01)
Symposium (Co-organisor)
 ESCI - European Society for Clinical Investigation, Netherlands
2017/05/17 - 2017/05/20 Organization of Workshop “Mitochondrial Biology and Medicine” (2017/05/17 - 2017/05/20)
Symposium (Co-organisor)
2017/05/16 - 2017/05/16 Member of Scientific Commission, MitoPorto meeting (2017/05/16 - 2017/05/16)
Seminar (Co-organisor)
 Universidade do Porto, Portugal
2016/04/27 - 2016/04/29 Organization of Workshop “Mitochondrial Biology and Medicine” (2016/04/27 - 2016/04/29)
Symposium (Co-organisor)
 ESCI - European Society for Clinical Investigation, Netherlands
2015/05/27 - 2015/05/30 Organization of Workshop “Mitochondria: from Organelle to Patient”, (2015/05/27 - 2015/05/30)
Symposium (Co-organisor)
 European Society for Clinical Investigation, Netherlands
2015/02/02 - 2015/02/03 Chair of the Meeting “Cancer Epigenetics and Metabolism: Connecting the Dots”, (2015/02/02 - 2015/02/03)
Seminar (Co-organisor)
 Biocant Associação de Transferência de Tecnologia, Portugal
2014/11/21 - 2014/11/21 Co-organizer of the Workshop “Integrating Biomarkers and Cell Physiology for Metabolic Profiling: Next Generation Approaches and Technologies” (2014/11/21 - 2014/11/21)
Symposium (Co-organisor)
 Biocant Associação de Transferência de Tecnologia, Portugal
2014/04/28 - 2014/05/02 Organization of Workshop “Mitochondrial Translational Medicine”, part of the Annual Meeting of the European Society of Clinical Investigation (2014/04/28 - 2014/05/02)
Symposium (Co-organisor)
 European Society for Clinical Investigation, Netherlands
2013/04/17 - 2013/04/20 President of the Local Organization of the 47th Annual Meeting of the European Society for Clinical Investigation and Organization of the workshop “Mitochondrial Physiology: From Basic Research to the Clinic” (2013/04/17 - 2013/04/20)
Seminar (Co-organisor)
 European Society for Clinical Investigation, Netherlands
2012/03/22 - 2012/03/23 Organization of Workshop “Mitochondria in Health and Disease”, part of the Annual Meeting of the European Society of Clinical Investigation, Budapest (2012/03/22 - 2012/03/23)
Symposium (Co-organisor)
 ESCI - European Society for Clinical Investigation, Netherlands
2010/05/11 - 2010/05/14 Organization of the Meeting “Survival or Death as a Matter of Fat” (International Courses on Toxicology 2010) (2010/05/11 - 2010/05/14)
Seminar (Co-organisor)
 CNC.IBILI, Portugal
2009/05/05 - 2009/05/09 Organization of the Meeting “Mitochondria: Between Life and Death” (International Courses on Toxicology 2009) (2009/05/05 - 2009/05/09)
Seminar (Co-organisor)
 CNC.IBILI, Portugal
2008/04/09 - 2008/04/11 Organization of the Meeting “Metabolic Toxicology, From Pathway to Organism” (International Courses on Toxicology 2008) (2008/04/09 - 2008/04/11)
Seminar (Co-organisor)
 CNC.IBILI, Portugal
2007/03/21 - 2007/03/23 Organization of the Meeting “Stem cells as a Tool in Toxicology” (International Courses on Toxicology 2007) (2007/03/21 - 2007/03/23)
Seminar (Co-organisor)
 CNC.IBILI, Portugal
2006/03/22 - 2006/03/24 Organization of the Meeting “Smart Toxicology: Subcellular Targets of Anti-cancer Therapy” (International Courses on Toxicology 2006) (2006/03/22 - 2006/03/24)
Seminar (Co-organisor)
 CNC.IBILI, Portugal
2005/04/27 - 2005/04/29 Organization of the Meeting “Mitochondria: Between Life and Death” (International Courses on Toxicology 2005) (2005/04/27 - 2005/04/29)
Seminar (Co-organisor)
 CNC.IBILI, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2019/05/01 - Current Section Editor - European Journal of Clinical Investigation Wiley
2004/12/01 - Current Reviewer adhoc in more than 30 scientific journals including Aging, AJP, BBA, FASEB Journal, Nature Protocols, Circulation Research

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/03/04 - 2023/03/31 Molecular Biology of Cancer Biologia Celular e Molecular (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2000/01/01 - Current Acta Physiologica
2000/01/01 - Current American Journal of Anatomy and Physiology
2000/01/01 - Current Biochemical Pharmacology (0006-2952) Elsevier
2000/01/01 - Current Biochemical Journal (1470-8728) Portland Press
2000/01/01 - Current Biochimica et Biophysica Acta (BBA) - Bioenergetics (0005-2728) Elsevier
2000/01/01 - Current BMC Cancer (1471-2407) Springer (Biomed Central Ltd.)
2000/01/01 - Current British Journal of Pharmacology (1476-5381) Wiley (Blackwell Publishing)
2000/01/01 - Current British Journal of Sports Medicine (1473-0480) BMJ
2000/01/01 - Current Cancer Biology & Therapy (1555-8576) Landes Bioscience
2000/01/01 - Current Cardiovascular Toxicology (1530-7905) Springer-Verlag
2000/01/01 - Current Cell Biology and Toxicology (1573-6822) Springer-Verlag
2000/01/01 - Current Cell Death and Disease (2041-4889) Springer Science and Business Media LLC
2000/01/01 - Current Environmental Chemistry Letters (1610-3661) Springer-Verlag
2000/01/01 - Current Environmental Technology (1479-487X) Informa UK (Taylor & Francis)
2000/01/01 - Current Epigenetics (1559-2308) Landes Bioscience
2000/01/01 - Current European Journal of Applied Physiology (1439-6327) Springer-Verlag
2000/01/01 - Current European Journal of Clinical Investigation (1365-2362) Wiley (Blackwell Publishing)
2000/01/01 - Current Journal of Cellular and Molecular Medicine (1582-4934) Wiley (Blackwell Publishing)
2000/01/01 - Current Expert Review of Molecular Diagnostics (1744-8352) Informa UK (Taylor & Francis)
2000/01/01 - Current Experimental Biology and Medicine (1535-3699) SAGE Publications
2000/01/01 - Current FEBS Letters (1873-3468) Wiley (John Wiley & Sons)
2000/01/01 - Current Free Radical Research (1029-2470) Informa UK (Taylor & Francis)
2000/01/01 - Current Frontiers in Bioscience (1093-4715) Frontiers in BioScience
2000/01/01 - Current International Journal of Cardiology (0167-5273) Elsevier
2000/01/01 - Current Journal of Applied Physiology (1522-1601) American Physiological Society
2000/01/01 - Current Journal of Cachexia Sarcopenia and Muscle (2190-6009) Wiley (John Wiley & Sons)
2000/01/01 - Current Journal of Experimental & Clinical Cancer Research (1756-9966) Springer (Biomed Central Ltd.)
2000/01/01 - Current The journal of nutrition health & aging (1760-4788) Springer-Verlag
2000/01/01 - Current Journal of Pharmacy and Pharmacology (2042-7158) Wiley (Blackwell Publishing)
2000/01/01 - Current The Journal of Physiology (1469-7793) Wiley (Blackwell Publishing)
2000/01/01 - Current Mitochondrion (1567-7249) Elsevier
2000/01/01 - Current Molecular Pharmacology (1521-0111) American Society for Pharmacology & Experimental Therapeutics
2000/01/01 - Current Nature Protocols (1754-2189) Springer Science and Business Media LLC
2000/01/01 - Current Nutrients (2072-6643) MDPI AG
2000/01/01 - Current Physiological Genomics (1531-2267) American Physiological Society
2000/01/01 - Current PLoS ONE (1932-6203) Public Library of Science
2000/01/01 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2000/01/01 - Current Trends in Molecular Medicine (1471-4914) Elsevier
2000/01/01 - Current Toxicology in Vitro (0887-2333) Elsevier
2000/01/01 - Current Toxicological Sciences (1096-0929) Oxford University Press
2000/01/01 - Current Toxicology and Applied Pharmacology (1096-0333) Elsevier
2000 - Current Frontiers in Oncology
Distinctions

Award

2022 Prize for Best Oral Presentation
2021 Poster Award (Senior Author)
Sociedade Portuguesa de Diabetes, Portugal
2021 Poster Award (co-author)
International Society of Microbiota, France
2020 Poster Award (senior author)
European Society for Clinical Investigation, Netherlands
2020 Poster Award (senior author)
ESCI - European Society for Clinical Investigation, Netherlands
2020 Poster Award (co-author)
ESCI - European Society for Clinical Investigation, Netherlands
2020 Poster Award (senior author)
ESCI - European Society for Clinical Investigation, Netherlands
2020 Poster Award (senior author)
ESCI - European Society for Clinical Investigation, Netherlands
2020 Poster Award (senior author)
European Society for Clinical Investigation, Netherlands

Other distinction

2019 Poster Award (senior author)
SRI - Society for Reproductive Investigation, United States
2018 FLAD Healthcare 2020
Fundação Luso-Americana, Portugal
2018 Best Oral Talk (senior author)
Sociedade Portuguesa de Diabetes, Portugal
2018 Poster Award (senior author)
European Society for Clinical Investigation, Netherlands
2018 Poster Award (co-author)
European Society for Clinical Investigation, Netherlands
2018 Poster Award (senior author)
European Society for Clinical Investigation, Netherlands
2015 Senior author of Poster Award at the 49th Annual Meeting of the European Society for Clinical Investigation, Cluj-Napoca, Romania. “New Paradigms in Anticancer Combined Therapy: Targeting Dietary Antioxidants to Mitochondria” (Kátia Santos)
European Society for Clinical Investigation, Netherlands
2014 Poster Award at the 48th Annual Scientific Meeting of the European Society for Clinical Investigation, “Physical Exercise Modulates Brain Cortex and Cerebellum Mitochondrial OXPHOS, Redox Status, Apoptotic Signaling, Mitochondrial Dynamics and Auto(mito)p
European Society for Clinical Investigation, Netherlands
2014 Co-author of Young Research Award communication at the Asia Pacific Lung Cancer Congress 2014, “Metabolic Coupling in Lung Cancer Cell Lines by 13C NMR isotopomer Analysis” (Ludgero C. Tavares)
International Association for the Study of Lung Cancer, United States
2004 Best Young Researcher in Basic Investigation
Sociedade Portuguesa de Cardiologia, Portugal
2003 Best Young Researcher in Basic Investigation Prize (co-author)
Sociedade Portuguesa de Cardiologia, Portugal
2003 Prize Aventis for Scientific Research (co-author)
Sanofi Spa, Italy
1999 Prize for Merit
1998 Prize for Merit
1997 Prize for Merit