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Ricardo Alexandre Rodrigues Pires finished his PhD in Materials Science and Engineering in 2004/12/09 by the Technical University of Lisbon, Technical Superior Institute and the graduation in Technological Chemistry in 1998/12/01 by the University of Lisbon, Faculty of Sciences. He is Principal Investigator from the University of Minho, President of the Council of the Unit I3Bs and member of the Academic Senate of the University of Minho. He published 72 papers in international scientific journals , 9 book chapters and he registered 4 patents. He supervised 15 students/researchers at different (post-)graduation level, including: 4 PhD and 2 MSc thesis. He participates or participated as a researcher in different scientific/industrial projects with a budget of ~8.5M€ (Host)/~18M€ (Total). His research is centred in the field of Materials Science and Engineering applied to the biomedical field, in particular in the areas of Neurosciences, Bionanotechnology e Biochemistry. During his research activities he interacted with 150 collaborators in co-autorships of scientific publications. In his CV at Ciência Vitae the most frequent keywords that are related with his professional activities are: self-assembly; supramolecular systems; hydrogels; Cancer; 3D disease models; metastasis; hyaluronic acid; gastric cancer; peptide/protein aggregation; amyloid; beta-sheet breakers; protein secondary structure; oligomers; nanofibres; ECM mimics. In the past years he has been dedicated to the development of systems able to reduce the cytotoxicity of different types of amyloids present in neurodegenerative disorders, e.g. Alzheimer's Disease. In particular, he is currently developing nanosystems (e.g. dendrimers) that are able to present different chemical moieties (e.g. saccharides and phenolic) and modulate the aggregation of amyloid-beta 42 (Ab42, a hallmark of Alzheimer's Disease), as well as to control the Ab42 cytotoxicity. He his also developing different types of hydrogels using glycosaminoglycans, supramolecular systems generated by short peptide amphiphiles, or their combination to generate mimics of the extracellular matrix of different tissues. These mimics are tuned to be able to recapitulate the biological environment in healthy and pathological (e.g. cancer) states. While the ones that mimic the pathological states (e.g. cancer) are being developed as platforms to study the cancer onset, evolution, invasiveness in response to the hydrogel composition. These hydrogels are also being used to screen the efficacy of different cancer drugs. In the case of the mimics of the extracellular matrix of the healthy cells, the systems are being tested for tissue engineering and regenerative medicine, namely for their capacity to promote the differentiation of stem cells while promoting the regeneration of the target tissue.
Identification

Personal identification

Full name
Ricardo Alexandre Rodrigues Pires

Citation names

  • Pires, Ricardo
  • Pires, Ricardo A
  • Pires, R A

Author identifiers

Ciência ID
E511-56A0-F77A
ORCID iD
0000-0002-9197-0138
Researcher Id
A-1595-2009
Scopus Author Id
8129144800

Telephones

Telephone
  • 253510907 (Professional)

Addresses

  • Universidade do Minho, I3Bs, Grupo 3Bs, Avepark, Zona Industrial da Gandra, 4805-017, Barco, Taipas, Guimarães, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Engineering and Technology - Nano-technology - Nano-materials
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2004/12/09
Concluded
Engenharia de Materiais (Doutoramento)
Major in Biomateriais
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Ionómeros de Vidro para utilização em medicina dentária: síntese e estudo por técnicas avançadas de espectroscopia e imagem de ressonância magnética nuclear" (THESIS/DISSERTATION)
1998/12/01
Concluded
Química Tecnológica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
15
Affiliation

Science

Category
Host institution
Employer
2013/08/01 - Current Contracted Researcher (Research) Universidade do Minho, Portugal
Universidade do Minho, Portugal
2009/01/01 - 2013/12/31 Postdoc (Research) Universidade do Minho, Portugal
2005/02/01 - 2008/12/31 Postdoc (Research) Universidade do Minho, Portugal
2000/01/01 - 2005/01/31 Researcher (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
1999/01/01 - 1999/12/31 Researcher (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal

Positions / Appointments

Category
Host institution
Employer
2018/09/19 - Current President of the I3Bs Unit Council Universidade do Minho, Portugal

Others

Category
Host institution
Employer
2023/12/01 - Current Member of the Academic Senate Universidade do Minho, Portugal
Universidade do Minho, Portugal
Projects

Grant

Designation Funders
2010/01 - 2012/12 GlueCork - Novos aglomerantes baseados em componentes da cortiça
GlueCork-5396
QREN - FEDER
2010/01 - 2012/12 WaterCork - Valorização de subprodutos da indústria de cortiça na remoção de contaminantes (orgânicos) em águas
WaterCork-5523
QREN - FEDER

Contract

Designation Funders
2021/09/01 - Current EcaBox - "Eyes in a Care Box": Regenerating human retina from resuscitated cadaveric eyes
964342-EcaBox
Researcher
2023/04/19 - 2029/04/18 NANOPATH - Nanosystems for the modulation of pathological protein aggregation in neurodegenerative disorders
2022.05623.CEECIND/CP1718/CT0014
Principal investigator
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/09/30 - 2025/09/29 RePark - Refining the efficacy of systemic administration of bioactive molecules for Parkinson's Disease
M-ERA-NET3/0007/2021
Principal investigator
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2024/12/31 Inorganic-Templated and Polymeric Layer-by-Layer Microcapsules with Multimodal Drug Loading to Treat Breast Cancer
PTDC/CTM-REF/0022/2020
Researcher
2020/04/01 - 2024/03/31 MEPHOS - Shaping the Mechano-Pharmacological properties of Microparticles and Extracellular Vesicles for the Treatment of Osteoarthritis
872648-MEPHOS
Researcher
Ongoing
2021/02/01 - 2024/01/31 Microcápsulas Poliméricas Obtidas por Automontagem Camada-a-Camada em Suportes Inorgânicos Com Capacidade de Encapsulamento Multimodal de Drogas Para o Tratamento do Cancro da Mama
PTDC/CTM-REF/0022/2020
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2024 THE DISCOVERIES CTR – Implementation of the Discoveries Centre for Regenerative and Precision Medicine, a new Centre of Excellence in Portugal
H2020-WIDESPREAD-01-2016-2017-739572
Researcher
Universidade do Minho, Portugal
EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation
Ongoing
2021/03/01 - 2023/03/31 Bio4Cork+ - Technical cork-polymer biocomposites for application in the wine industry
Bio4Cork+
Researcher
2021/11/02 - 2023/03/01 CEEC Institutional
CEECINST/00077/2018/CP1640/CT0004
Researcher
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 Self-Healing Hydrogels with Extracellular Matrix Analogues for Cardiac Tissue Engineering
PTDC/BTM-MAT/28327/2017
Principal investigator
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 Smart Carbohydrate Nanonets for selective anticancer therapies
PTDC/NAN-MAT/28468/2017
Researcher
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2020 INtegrated Conductive and biomimetic polymeric Interfaces able to serve as micro-nanostructured Patches for myocardIal regeneraTion
M-ERA-NET2/0001/2016
Researcher
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2015 - 2020 FoReCaST - Forefront Research in 3D Disease Cancer Models as in vitro Screening Technologies
FP7-ERAChairs-PilotCall-2013-621399-FoReCaST
Researcher
EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation
Ongoing
2016 - 2018 CHEM2NATURE – Enabling precision chemical methodologies applied to natural-based systems for the development of multifunctional biomedical devices
H2020-TWINN-2015-692333
Researcher
EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation
Concluded
2012 - 2015 POLARIS – Unlocking the research potential of 3Bs Group, University of Minho, in the Nanomedicine field to strengthen its competitive position at the European level
FP7-REGPOT-2012-CT2012-316331
Researcher
EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 23 - 2011-2012
PEst-OE/EQB/LA0023/2011
Universidade do Minho, Portugal

Universidade do Algarve, Portugal

Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Fundação Gaspar Frutuoso, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade dos Açores, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2012 BioActiveCork - Extracção e isolamento de compostos de elevado potencial biológico de subprodutos da indústria corticeira
BioActiveCork
Researcher
Concluded
2009 - 2011 NovelComp - Desenvolvimento de novos materiais compósitos cortiça-polímero com base na valorização de resíduos de cortiça
NovelComp-3107
Researcher
Concluded
2005 - 2008 WaCheUp – New concepts for upgrading pulp and cork mill waste streams to value-added chemicals
NMP2-CT-2005-013896
Researcher
European Commission Sixth Framework Programme
Concluded
2000 - 2004 Development of new materials in dentistry: synthesis, properties and in-vitro studies using non-invasive advanced techniques
POCTI 33193/FCB/2000
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1998 - 2000 Oclusal sealants and dental adhesives: New in-vitro studies using NMR advanced techniques and mechanical spectrometry
PRAXIS XXI - C/SAU/131/96
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Amorim, Sara; Reis, Rui L.; Pires, Ricardo. "Hyaluronan-based hydrogels as modulators of cellular behaviour". In Multifunctional Hydrogels for Biomedical Applications. Wiley, 2022.
    Published
  2. Pires, Ricardo A.; Abul-Haija, Yousef M.; Reis, Rui L.; Ulijn, Rein V.; Pashkuleva, Iva. "Hydrogel Nanomaterials for Cancer Diagnosis and Therapy". In Hydrogels: Design, Synthesis and Application in Drug Delivery & Regenerative Medicine, 170-183. CRC Press, 2018.
    10.1201/9781315152226-10
  3. Brito, Alexandra; Reis, Rui L.; Pires, Ricardo A.; Pashkuleva, Iva. "Sweet building blocks for self-assembling biomaterials with molecular recognition". In Self-assembling Biomaterials, 79-94. Elsevier, 2018.
    10.1016/b978-0-08-102015-9.00005-8
  4. Fernandes, Emanuel M.; Pires, Ricardo A; Reis, Rui L.. "Cork biomass biocomposites: lightweight and sustainable materials". In Lignocellulosic Fibre and Biomass-Based Composite Materials. Elsevier, 2017.
    Published
  5. Barros, Alexandre A.; Leite, Álvaro J.; Pires, Ricardo A.; Mano, João F.; Reis, Rui L.. "Bioactive Composites Reinforced with Inorganic Glasses and Glass–Ceramics for Tissue Engineering Applications". In Advances in Calcium Phosphate Biomaterials, 331-353. Springer Berlin Heidelberg, 2014.
    Published • 10.1007/978-3-642-53980-0_10
  6. Pereira, David M.; Andrade, Paula B.; Pires, Ricardo A; Reis, Rui L.. "Chemical Ecology of Echinoderms: Impact of Environment and Diet in Metabolomic Profile". In Chemical Ecology of Echinoderms. 2014.
    Published
Conference paper
  1. Barros, Alexandre; Duarte, Ana Rita C.; Oliveira, Carlos; Pires, Ricardo; Lima, Estêvão; Reis, Rui L.. "Bioresorbable urological stent systems based on natural polymers: update". Paper presented in 5th Meeting ICVS/3B's, Braga, 2015.
    Published
  2. Monteiro, Nelson; Martins, Albino; Pires, Ricardo; Faria, Susana; Fonseca, Nuno A; Moreira, João N.; Reis, Rui L.; Neves, Nuno M.. "TS40 - Immobilization of bioactive factor-loaded liposomes at the surface of electrospun nanofibers targeting tissue engineering strategies". Paper presented in TERM STEM 2013 Nanotechnology as a Tool for Improving Tissue Engineering and Regenerative Medicine, 2013.
    Published • 10.1002/term.1822
  3. Barros, Alexandre A. A.; Duarte, Ana Rita C.; Pires, Ricardo A; Lima, Estêvão; Mano, João F.; Reis, Rui L.. "Tailor made degradable ureteral stents from natural origin polysaccharides". Paper presented in 10th Conference on Supercritical Fluids and Their Applications, 2013.
  4. Mestre, Ana S.; Pires, Ricardo A; Aroso, Ivo; Fernandes, Emanuel M.; Reis, Rui L.; Silva, Susana P.; Carvalho, Ana P.. "Cork-based activated carbons for pharmaceutical compounds removal". Paper presented in Carbon 2013, 2013.
  5. Fernandes, E.M.; Aroso, I.; Pires, R.A.; Correlo, V.M.; Pitkänen, P.; Koskimies, S.; Mano, J.F.; Reis, R.L.. "Improvement on the mechanical properties of cork composites using suberin as coupling agent through a reactive extrusion process". 2011.
  6. Fernandes, Emanuel M.; Aroso, Ivo; Pires, Ricardo A; Correlo, Vitor M.; Pitkänen, P.; Koskimies, S.; Mano, João F.; Reis, Rui L.. "Improvement on the mechanical properties of cork composites using suberin as coupling agent through a reactive extrusion process". Paper presented in Annual Technical Conference of the Society of Plastics Engineeres (SPE), 2011.
  7. Pires, R.A.; Abrahams, I.; Nunes, T.G.; Hawkes, G.E.. "31P Nuclear Magnetic Resonance and X-Ray Diffraction Studies of Na-Sr-Phosphate Glass-Ceramics". Paper presented in Bioceramics, Porto, 2004.
    Published
  8. Pires, Ricardo A; Abrahams, Isaac; Nunes, Teresa G.; Hawkes, Geoffrey E.. "31P nuclear magnetic resonance and X-ray diffraction studies of Na-Sr-phosphate glass-ceramics". Paper presented in Key Engineering Materials, 2004.
  9. Pires, Ricardo A; Nunes, Teresa G.; Hawkes, Geoffrey E.; Abrahams, Isaac. "1H-19F Stray-field Magnetic Resonance Imaging studies of a Commercial Glass Ionomer Cement". Paper presented in Annals of Magnetic Resonance, 2004.
  10. Ferreira, M. C.; Duarte, Maria L.; Marvão, M. R.; Pires, Ricardo A. "FT-IR Spectroscopy as a tool to determine the degree of acetylation of beta-chitin/chitosan from loligo pen". Paper presented in Proceedings of the 3rd Asia-Pacific Chitin/Chitosan Symposium, 1998.
Conference poster
  1. Castro, Vânia I. B.; Amorim, Sara; Caballero, David; Abreu, Catarina M.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo. "Micropatterned glycopeptide-based supramolecular hydrogels promote the alignment and contractility of cardiomyocytes". Paper presented in TERMIS-EU 2023, 2023.
  2. Castro, Vânia I. B.; Ana Rita Araujo; António Duarte Zapico Bicho de Sousa Franco; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo A. "Supramolecular hydrogels induce differentiation of stem cell into neural lineages". Paper presented in Third Achilles Workshop, 2021.
  3. Dudik, Olesia; Amorim, Sara; Silva, Tiago H.; Pires, Ricardo; Reis, Rui L.. "Evaluation of osteogenic potential of sponge-derived biosilica for bone tissue engineering applications". Paper presented in Forecast Final Conference, 2021.
  4. Dudik, Olesia; Amorim, Sara; Soares da Costa, Diana; Silva, Tiago H; Pires, Ricardo A; Reis, Rui L.. "Modified mesoporous silica nanoparticles improves BMP2 loading and its release timeframe". Paper presented in TERMSTEM 2019, 2019.
  5. Castro, Vânia I. B.; Ge, J.; Chen, J.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo. "Carbohydrates can code bioinformation by inversion of the supramolecular chirality". Paper presented in TermStem 2019, 2019.
  6. Castro, Vania; Gao, Yuting; Brito, Alexandra; Soares da Costa, Diana; Chen, J.; Ulijn, R.V.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo A. "Different energy inputs promotes helicity change in the supramolecular arrangement of carbohydrates". Paper presented in 1st Discoveries Forum, 2019.
  7. Amorim, Sara; Soares da Costa, Diana; Pashkuleva, Iva; Reis, CA; Reis, Rui L.; Pires, Ricardo A. "Immobilized oligosaccharides of hyaluronic acid induce the migration and proliferation of AGS gastric cancer cells through the activation of the AKT pathway". Paper presented in 1st Discoveries Forum, 2019.
  8. Dudik, Olesia; Amorim, Sara; Soares da Costa, Diana; Silva, Tiago H; Pires, Ricardo A; Reis, Rui L.. "Development of mesoporous silica-based nanoparticles as BMP-2 controled release systems". Paper presented in 1st Discoveries Forum, 2019.
  9. Castro, Vânia I. B.; Yuting Gao; Brito, Alexandra; Soares da Costa, Diana; Jien Chen; Reis, Rui L.; Rein V. Ulijn; Pashkuleva, Iva; Pires, Ricardo. "Carbohydrate stereoisomers self-assemble into supramolecular fibers with different helicity". Paper presented in Glupor13, 2019.
  10. Castro, Vânia I. B.; Gao, Yuting; Brito, Alexandra; Soares da Costa, Diana; Chen, J.; Rein V. Ulijn; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo A. "Out of equilibrium assembly of carbohydrate amphiphiles as a modulator of supramolecular helicity and gelation". Paper presented in Forecast 2nd Workshop, 2019.
  11. Sousa-Franco, António; Soares da Costa, Diana; Reis, Rui L.; Adams, David J.; Pashkuleva, Iva; Pires, Ricardo A. "Minimalistic supramolecular hydrogels for tissue engineering and regenerative medicine". Paper presented in 2nd Achilles Conference, 2019.
  12. Dudik, Olesia; Amorim, Sara; Soares da Costa, Diana; Silva, Tiago H; Pires, Ricardo A; Reis, Rui L.. "Silica-based nanoparticles as BMP-2 localized delivery systems for bone tissue engineering applications". Paper presented in 2nd Achilles Conference, 2019.
  13. Castro, Vânia I. B.; Gao, Y.; Brito, Alexandra; Soares da Costa, Diana; Chen, J.; Ulijn, R. V.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo. "Out of equilibrium assembly of carbohydrate amphiphiles as a modulator of the supramolecular helicity and gelation". Paper presented in FoReCast 2nd Workshop, 2019.
  14. Yuting Gao; Brito, Alexandra; Jien Chen; Rein V. Ulijn; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo A. "Control of supramolecular helicity by the energy input and the monomer stereochemistry". Paper presented in TERMIS-EU 2020 Chapter Meeting, 2019.
  15. Castro, Vânia I. B.; Gao, Y.; A. Brito; Chen, J.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo. "Effect of stereochemistry on the assembly and properties of supramolecular structures made of short aromatic carbohydrate amphiphiles". Paper presented in Chem2Nature_Final Conference, 2018.
  16. Castro, Vânia I. B.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo. "Supramolecular hydrogels generated by short peptide sequences that mimic the extracellular matrix". Paper presented in Chem2Nature, 2018.
  17. Gomes, Sandra F.; Brito, Alexandra; Caballero, David; Brancato, Virginia; Soares da Costa, Diana; Kundu, Subhas; Martins, Ana M.; Pashkuleva, Iva; Pires, Ricardo A. "Micropatterned supramolecular hydrogels promote cell alignment for myocardium regeneration". Paper presented in Chem2Nature, 2018.
  18. Brito, Alexandra; Gomes, Sandra F.; Caballero, David; Soares da Costa, Diana; Kundu, Subhas; Martins, Ana M.; Pashkuleva, Iva; Reis, Rui L.; Pires, Ricardo A. "Development of micropatterned supramolecular hydrogels for myocardium regeneration". Paper presented in Chem2Nature Final Conference, 2018.
Journal article
  1. Sara Amorim; Olesia Dudik; Diana Soares da Costa; Rui L. Reis; Tiago H. Silva; Ricardo A. Pires. "Fucoidan-Coated Silica Nanoparticles Promote the Differentiation of Human Mesenchymal Stem Cells into the Osteogenic Lineage". ACS Biomaterials Science & Engineering (2023): https://doi.org/10.1021/acsbiomaterials.3c00265.
    10.1021/acsbiomaterials.3c00265
  2. Vânia I.B. Castro; Ana R. Araújo; Filipa Duarte; António Sousa-Franco; Rui L. Reis; Iva Pashkuleva; Ricardo A. Pires. "Glycopeptide-Based Supramolecular Hydrogels Induce Differentiation of Adipose Stem Cells into Neural Lineages". ACS Applied Materials & Interfaces (2023): https://doi.org/10.1021/acsami.3c05309.
    10.1021/acsami.3c05309
  3. Catarina S. Silva; Rute D. Pinto; Ricardo A. Pires; Margarida Correia-Neves; Rui L. Reis; Nuno L. Alves; Albino Martins; Nuno M. Neves. "The Influence of Feeder Cell-Derived Extracellular Matrix Density on Thymic Epithelial Cell Culture". ACS Biomaterials Science & Engineering (2023): https://doi.org/10.1021/acsbiomaterials.3c00148.
    10.1021/acsbiomaterials.3c00148
  4. Sara Monteiro-Reis; João P. S. Ferreira; Ricardo A. Pires; João Lobo; João A. Carvalho; Rui L. Reis; Renato Natal Jorge; Carmen Jerónimo. "Bladder Wall Stiffness after Cystectomy in Bladder Cancer Patients: A Preliminary Study". Cancers (2023): https://doi.org/10.3390/cancers15020359.
    10.3390/cancers15020359
  5. Ana L. Alves; Ana C. Carvalho; Inês Machado; Gabriela S. Diogo; Emanuel M. Fernandes; Vânia I. B. Castro; Ricardo A. Pires; et al. "Cell-Laden Marine Gelatin Methacryloyl Hydrogels Enriched with Ascorbic Acid for Corneal Stroma Regeneration". Bioengineering (2023): https://doi.org/10.3390/bioengineering10010062.
    10.3390/bioengineering10010062
  6. Eva Martins; Gabriela S. Diogo; Ricardo Pires; Rui L. Reis; Tiago H. Silva. "3D Biocomposites Comprising Marine Collagen and Silica-Based Materials Inspired on the Composition of Marine Sponge Skeletons Envisaging Bone Tissue Regeneration". Marine Drugs (2022): https://doi.org/10.3390/md20110718.
    10.3390/md20110718
  7. D. Caballero; B. Kundu; C. M. Abreu; S. Amorim; D. C. Fernandes; R. A. Pires; J. M. Oliveira; et al. "Forecast cancer: the importance of biomimetic 3D in vitro models in cancer drug testing/discovery and therapy". In vitro models (2022): https://doi.org/10.1007/s44164-022-00014-z.
    10.1007/s44164-022-00014-z
  8. Ana R. Araújo; Juan Correa; Vicente Dominguez-Arca; Rui L. Reis; Eduardo Fernandez-Megia; Ricardo A. Pires. "Functional Gallic Acid-Based Dendrimers as Synthetic Nanotools to Remodel Amyloid-ß-42 into Noncytotoxic Forms". ACS Applied Materials & Interfaces (2021): https://doi.org/10.1021/acsami.1c17823.
    10.1021/acsami.1c17823
  9. Alexandra Brito; Dhwanit Dave; Ayala Lampel; Vânia I. B. Castro; Daniela Kroiss; Rui L. Reis; Tell Tuttle; et al. "Expanding the Conformational Landscape of Minimalistic Tripeptides by Their O-Glycosylation". Journal of the American Chemical Society (2021): https://doi.org/10.1021/jacs.1c07592.
    10.1021/jacs.1c07592
  10. Ana L. Silva; Pedro S. Babo; Márcia T. Rodrigues; Ana I. Gonçalves; Ramon Novoa-Carballal; Ricardo A. Pires; Jeroen Rouwkema; Rui L. Reis; Manuela E. Gomes. "Hyaluronic Acid Oligomer Immobilization as an Angiogenic Trigger for the Neovascularization of TE Constructs". ACS Applied Bio Materials (2021): https://doi.org/10.1021/acsabm.1c00291.
    10.1021/acsabm.1c00291
  11. Ana R. Araújo; Vânia I. B. Castro; Rui L. Reis; Ricardo A. Pires. "Glucosamine and Its Analogues as Modulators of Amyloid-ß Toxicity". ACS Medicinal Chemistry Letters 12 4 (2021): 548-554. https://doi.org/10.1021/acsmedchemlett.0c00350.
    10.1021/acsmedchemlett.0c00350
  12. Ana R. Araújo; Ana C. Araújo; Rui L. Reis; Ricardo A. Pires. "Vescalagin and Castalagin Present Bactericidal Activity toward Methicillin-Resistant Bacteria". ACS Biomaterials Science & Engineering (2021): https://doi.org/10.1021/acsbiomaterials.0c01698.
    10.1021/acsbiomaterials.0c01698
  13. Sara Amorim; Celso A. Reis; Rui L. Reis; Ricardo A. Pires. "Extracellular Matrix Mimics Using Hyaluronan-Based Biomaterials". Trends in Biotechnology (2021): https://doi.org/10.1016/j.tibtech.2020.06.003.
    10.1016/j.tibtech.2020.06.003
  14. Sara Amorim; Diana Soares da Costa; Iva Pashkuleva; Celso A. Reis; Rui L. Reis; Ricardo A. Pires. "3D hydrogel mimics of the tumor microenvironment: the interplay among hyaluronic acid, stem cells and cancer cells". Biomaterials Science (2021): https://doi.org/10.1039/D0BM00843E.
    10.1039/D0BM00843E
  15. Brito, Alexandra; Kassem, Salma; Reis, Rui L.; Ulijn, Rein V.; Pires, Ricardo A.; Pashkuleva, Iva. "Carbohydrate amphiphiles for supramolecular biomaterials: Design, self-assembly, and applications". Chem (2021): https://publons.com/publon/50855752/.
    10.1016/J.CHEMPR.2021.04.011
  16. Alheib, Omar; da Silva, Lucilia P.; Caballero, David; Pires, Ricardo A.; Kundu, Subhas C.; Correlo, Vitor M.; Reis, Rui L.. "Micropatterned gellan gum-based hydrogels tailored with laminin-derived peptides for skeletal muscle tissue engineering". Biomaterials (2021): https://publons.com/publon/47704976/.
    10.1016/J.BIOMATERIALS.2021.121217
  17. Riveiro, Antonio; Amorim, Sara; Solanki, Anu; Costa, Diana S.; Pires, Ricardo A.; Quintero, Felix; del Val, Jesus; et al. "Hyaluronic acid hydrogels reinforced with laser spun bioactive glass micro- and nanofibres doped with lithium". Materials Science and Engineering: C (2021): https://publons.com/publon/45390621/.
    10.1016/J.MSEC.2021.112124
  18. Dudik, Olesia; Amorim, Sara; Xavier, Joana R.; Rapp, Hans Tore; Silva, Tiago H.; Pires, Ricardo A.; Reis, Rui L.. "Bioactivity of Biosilica Obtained From North Atlantic Deep-Sea Sponges". Frontiers in Marine Science (2021): https://publons.com/publon/46385313/.
    10.3389/FMARS.2021.637810
  19. Amorim, Sara; da Costa, Diana Soares; Mereiter, Stefan; Pashkuleva, Iva; Reis, Celso A.; Reis, Rui L.; Pires, Ricardo A.. "Multilayer platform to model the bioactivity of hyaluronic acid in gastric cancer". Materials Science and Engineering: C (2021): https://publons.com/publon/34572317/.
    10.1016/J.MSEC.2020.111616
  20. Araujo, Ana R.; Camero, Sergio; Taboada, Pablo; Reis, Rui L.; Pires, Ricardo A.. "Vescalagin and castalagin reduce the toxicity of amyloid-beta42 oligomers through the remodelling of its secondary structure (vol 56, pg 3187, 2020)". Chemical Communications (2021): https://publons.com/publon/46178535/.
    10.1039/D1CC90090K
  21. Catarina S. Silva; Rute D. Pinto; Sara Amorim; Ricardo A. Pires; Margarida Correia-Neves; Rui L. Reis; Nuno L. Alves; Albino Martins; Nuno M. Neves. "Fibronectin-Functionalized Fibrous Meshes as a Substrate to Support Cultures of Thymic Epithelial Cells". Biomacromolecules (2020): https://doi.org/10.1021/acs.biomac.0c00933.
    10.1021/acs.biomac.0c00933
  22. Sara Amorim; Diana Soares da Costa; Iva Pashkuleva; Celso A. Reis; Rui L. Reis; Ricardo A. Pires. "Hyaluronic Acid of Low Molecular Weight Triggers the Invasive Hummingbird Phenotype on Gastric Cancer Cells". Advanced Biosystems 4 11 (2020): 2000122-2000122. https://doi.org/10.1002/adbi.202000122.
    10.1002/adbi.202000122
  23. Sofia Oliveira; Tatiana Felizardo; Sara Amorim; Suzanne M. Mithieux; Ricardo A. Pires; Rui L. Reis; Albino Martins; Anthony S. Weiss; Nuno M. Neves. "Tubular Fibrous Scaffolds Functionalized with Tropoelastin as a Small-Diameter Vascular Graft". Biomacromolecules (2020): https://doi.org/10.1021/acs.biomac.0c00599.
    10.1021/acs.biomac.0c00599
  24. Ana R. Araújo; Sergio Camero; Pablo Taboada; Rui L. Reis; Ricardo A. Pires. "Vescalagin and castalagin reduce the toxicity of amyloid-beta42 oligomers through the remodelling of its secondary structure". Chemical Communications (2020): https://doi.org/10.1039/D0CC00192A.
    10.1039/D0CC00192A
  25. Alexandra Brito; Patrícia M. R. Pereira; Rui L. Reis; Rein V. Ulijn; Jason S. Lewis; Ricardo A. Pires; Iva Pashkuleva. "Aromatic carbohydrate amphiphile disrupts cancer spheroids and prevents relapse". Nanoscale (2020): https://doi.org/10.1039/D0NR05008C.
    10.1039/D0NR05008C
  26. Sara Amorim; Iva Pashkuleva; Celso A. Reis; Rui L. Reis; Ricardo A. Pires. "Tunable layer-by-layer films containing hyaluronic acid and their interactions with CD44". Journal of Materials Chemistry B (2020): https://doi.org/10.1039/D0TB00407C.
    10.1039/D0TB00407C
  27. Alexandra Brito; Patrícia M. R. Pereira; Diana Soares da Costa; Rui L. Reis; Rein V. Ulijn; Jason S. Lewis; Ricardo A. Pires; Iva Pashkuleva. "Inhibiting cancer metabolism by aromatic carbohydrate amphiphiles that act as antagonists of the glucose transporter GLUT1". Chemical Science (2020): https://doi.org/10.1039/D0SC00954G.
    10.1039/D0SC00954G
  28. Moreira, Joana; Vale, Ana C.; Pires, Ricardo A.; Botelho, Gabriela; Reis, Rui L.; Alves, Natalia M.. "Spin-Coated Polysaccharide-Based Multilayered Freestanding Films with Adhesive and Bioactive Moieties (vol 25, 840, 2020)". Molecules (2020): https://publons.com/publon/38740818/.
    10.3390/MOLECULES25122727
  29. Moreira, Joana; Vale, Ana C.; Pires, Ricardo A.; Botelho, Gabriela; Reis, Rui L.; Alves, Natalia M.. "Spin-Coated Polysaccharide-Based Multilayered Freestanding Films with Adhesive and Bioactive Moieties". Molecules (2020): https://publons.com/publon/31712610/.
    10.3390/MOLECULES25040840
  30. Araujo, Ana R.; Reis, Rui L.; Pires, Ricardo A.. "Natural Polyphenols as Modulators of the Fibrillization of Islet Amyloid Polypeptide". Advances in Experimental Medicine and Biology (2020): https://publons.com/publon/33371545/.
    10.1007/978-981-15-3262-7_11
  31. Canadas, Raphael F.; Patricio, Pedro; Brancato, Virginia; Gasperini, Luca; Caballero, David; Pires, Ricardo A.; Costa, Joao B.; et al. "Convection patterns gradients of non-living and living micro-entities in hydrogels". Applied Materials Today (2020): https://publons.com/publon/34914708/.
    10.1016/J.APMT.2020.100859
  32. Helena Almeida; Rui M. A. Domingues; Suzanne M. Mithieux; Ricardo A. Pires; Ana I. Gonçalves; Manuel Gómez-Florit; Rui L. Reis; Anthony S. Weiss; Manuela E. Gomes. "Tropoelastin-Coated Tendon Biomimetic Scaffolds Promote Stem Cell Tenogenic Commitment and Deposition of Elastin-Rich Matrix". ACS Applied Materials & Interfaces (2019): https://doi.org/10.1021/acsami.9b04616.
    10.1021/acsami.9b04616
  33. Alexandra Brito; Yousef M. Abul-Haija; Diana Soares da Costa; Ramon Novoa-Carballal; Rui L. Reis; Rein V. Ulijn; Ricardo A. Pires; Iva Pashkuleva. "Minimalistic supramolecular proteoglycan mimics by co-assembly of aromatic peptide and carbohydrate amphiphiles". Chemical Science (2019): https://doi.org/10.1039/C8SC04361B.
    10.1039/C8SC04361B
  34. Amorim, Sara; da Costa, Diana Soares; Freitas, Daniela; Reis, Celso A.; Reis, Rui L.; Pashkuleva, Iva; Pires, Ricardo A.. "Molecular weight of surface immobilized hyaluronic acid influences CD44-mediated binding of gastric cancer cells". Scientific Reports 8 1 (2018): http://dx.doi.org/10.1038/s41598-018-34445-0.
    10.1038/s41598-018-34445-0
  35. Rui R. Costa; Miguel González-Pérez; Marcos Herrero-Gutiérrez; Ricardo A. Pires; Matilde Alonso; J. Carlos Rodriguez-Cabello; Rui L. Reis; Iva Pashkuleva. "Tuning the Stiffness of Surfaces by Assembling Genetically Engineered Polypeptides with Tailored Amino Acid Sequence". Biomacromolecules (2018): https://doi.org/10.1021/acs.biomac.8b00723.
    10.1021/acs.biomac.8b00723
  36. Ana M. Carvalho; Raquel Teixeira; Ramón Novoa-Carballal; Ricardo A. Pires; Rui L. Reis; Iva Pashkuleva. "Redox-Responsive Micellar Nanoparticles from Glycosaminoglycans for CD44 Targeted Drug Delivery". Biomacromolecules (2018): https://doi.org/10.1021/acs.biomac.8b00561.
    10.1021/acs.biomac.8b00561
  37. Vieira, Sara; Franco, Albina R.; Fernandes, Emanuel M.; Amorim, Sara; Ferreira, Helena; Pires, Ricardo A.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Fish sarcoplasmic proteins as a high value marine material for wound dressing applications". Colloids and Surfaces B: Biointerfaces 167 (2018): 310-317. http://dx.doi.org/10.1016/j.colsurfb.2018.04.002.
    10.1016/j.colsurfb.2018.04.002
  38. Dudik, Olesia; Leonor, Isabel; Xavier, Joana R.; Rapp, Hans Tore; Pires, Ricardo A.; Silva, Tiago H.; Reis, Rui L.. "Sponge-derived silica for tissue regeneration". Materials Today 21 5 (2018): 577-578. http://dx.doi.org/10.1016/j.mattod.2018.03.025.
    10.1016/j.mattod.2018.03.025
  39. Helena Ferreira; Albino Martins; Marta L. Alves da Silva; Sara Amorim; Susana Faria; Ricardo A. Pires; Rui L. Reis; Nuno M. Neves. "The functionalization of natural polymer-coated gold nanoparticles to carry bFGF to promote tissue regeneration". Journal of Materials Chemistry B (2018): https://doi.org/10.1039/C7TB03273K.
    10.1039/C7TB03273K
  40. Bárbara B. Mendes; Manuel Gómez-Florit; Ricardo A. Pires; Rui M. A. Domingues; Rui L. Reis; Manuela E. Gomes. "Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior". Nanoscale (2018): https://doi.org/10.1039/C8NR04273J.
    10.1039/C8NR04273J
  41. Pires, Ricardo. "OBP fused with cell-penetrating peptides promotes liposomal transduction". Colloids and Surfaces B: Biointerfaces 161 (2018): 645-653. http://www.sciencedirect.com/science/article/pii/S0927776517307622.
    https://doi.org/10.1016/j.colsurfb.2017.11.026
  42. Goncalves, Filipa; Castro, Tarsila; Nogueira, Eugenia; Pires, Ricardo; Reis, Rui L.; Silva, Carla; Ribeiro, Artur; Cavaco-Paulo, Artur. "OBP fused with cell-penetrating and anchor peptides promotes liposomal transduction of 1-aminoanthracene". Abstracts of Papers of the American Chemical Society (2018): https://publons.com/wos-op/publon/19628750/.
  43. Ivo M. Aroso; Ana R. Araújo; Ricardo A. Pires; Rui L. Reis. "Cork: Current Technological Developments and Future Perspectives for this Natural, Renewable, and Sustainable Material". ACS Sustainable Chemistry & Engineering (2017): https://doi.org/10.1021/acssuschemeng.7b00751.
    10.1021/acssuschemeng.7b00751
  44. Fernandes, João S.; Gentile, Piergiorgio; Crawford, Aileen; Pires, Ricardo A.; Hatton, Paul V.; Reis, Rui L.. "Substituted Borosilicate Glasses with Improved Osteogenic Capacity for Bone Tissue Engineering". Tissue Engineering Part A 23 23-24 (2017): 1331-1342. http://dx.doi.org/10.1089/ten.tea.2016.0386.
    10.1089/ten.tea.2016.0386
  45. João S. Fernandes; Piergiorgio Gentile; Ricardo A. Pires; Rui L. Reis; Paul V. Hatton. "Multifunctional Bioactive Glass and Glass-Ceramic Biomaterials with Antibacterial Properties for Repair and Regeneration of Bone Tissue". Acta Biomaterialia (2017): https://doi.org/10.1016%2Fj.actbio.2017.06.046.
    10.1016/j.actbio.2017.06.046
  46. Aroso, Ivo M.; Araújo, Ana R.; Fernandes, João P.; Santos, Tânia; Batista, Maria T.; Pires, Ricardo A.; Mano, João F.; Reis, Rui L.. "Hydroalcoholic extracts from the bark of Quercus suber L. (Cork): optimization of extraction conditions, chemical composition and antioxidant potential". Wood Science and Technology 51 4 (2017): 855-872. http://dx.doi.org/10.1007/s00226-017-0904-y.
    10.1007/s00226-017-0904-y
  47. João S. Fernandes; Rui L. Reis; Ricardo A. Pires. "Wetspun poly-L-(lactic acid)-borosilicate bioactive glass scaffolds for guided bone regeneration". Materials Science and Engineering: C 71 (2017): 252-259. https://doi.org/10.1016/j.msec.2016.10.007.
    10.1016/j.msec.2016.10.007
  48. Araújo, Ana R.; Soares da Costa, Diana; Amorim, Sara; Reis, Rui L.; Pires, Ricardo A.; Pashkuleva, Iva. "Surfaces Mimicking Glycosaminoglycans Trigger Different Response of Stem Cells via Distinct Fibronectin Adsorption and Reorganization". ACS Applied Materials & Interfaces 8 42 (2016): 28428-28436. http://dx.doi.org/10.1021/acsami.6b04472.
    10.1021/acsami.6b04472
  49. Nelson Monteiro; Albino Martins; Ricardo A. Pires; Susana Faria; Nuno A. Fonseca; João N. Moreira; Rui L. Reis; Nuno M. Neves. "Dual release of a hydrophilic and a hydrophobic osteogenic factor from a single liposome". RSC Advances 6 115 (2016): 114599-114612. https://doi.org/10.1039/C6RA21623D.
    10.1039/C6RA21623D
  50. Fernandes, Joao S.; Gentile, Piergiorgio; Martins, Margarida; Neves, Nuno M.; Miller, Cheryl; Crawford, Aileen; Pires, Ricardo A.; Hatton, Paul; Reis, Rui L.. "Reinforcement of poly-L-lactic acid electrospun membranes with strontium borosilicate bioactive glasses for bone tissue engineering". Acta Biomaterialia 44 (2016): 168-177. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000385594700015&KeyUID=WOS:000385594700015.
    10.1016/j.actbio.2016.08.042
  51. Fernandes, Joao S.; Martins, Margarida; Neves, Nuno M.; Fernandes, Maria H. V.; Reis, Rui L.; Pires, Ricardo A.. "Intrinsic Antibacterial Borosilicate Glasses for Bone Tissue Engineering Applications". Acs Biomaterials Science & Engineering 2 7 (2016): 1143-1150. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000379638200008&KeyUID=WOS:000379638200008.
    10.1021/acsbiomaterials.6b00162
  52. Fernandes, Joao S.; Gentile, Piergiorgio; Moorehead, Robert; Crawford, Aileen; Miller, Cheryl A.; Pires, Ricardo A.; Hatton, Paul V.; Reis, Rui L.. "Design and Properties of Novel Substituted Borosilicate Bioactive Glasses and Their Glass-Ceramic Derivatives". Crystal Growth & Design 16 7 (2016): 3731-3740. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000379456700023&KeyUID=WOS:000379456700023.
    10.1021/acs.cgd.6b00231
  53. Aroso, Ivo M.; Duarte, Ana Rita C.; Pires, Ricardo R.; Mano, João F.; Reis, Rui L.. "Cork processing with supercritical carbon dioxide: Impregnation and sorption studies". The Journal of Supercritical Fluids 104 (2015): 251-258. http://dx.doi.org/10.1016/j.supflu.2015.06.024.
    10.1016/j.supflu.2015.06.024
  54. Barros, Alexandre A.; Duarte, Ana Rita C.; Pires, Ricardo A.; Sampaio-Marques, Belem; Ludovico, Paula; Lima, Estevao; Mano, Joao F.; Reis, Rui L.. "Bioresorbable ureteral stents from natural origin polymers". Journal of Biomedical Materials Research Part B-Applied Biomaterials 103 3 (2015): 608-617. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000351760000014&KeyUID=WOS:000351760000014.
    10.1002/jbm.b.33237
  55. Aroso, Ivo M.; Fernandes, Emanuel M.; Pires, Ricardo A.; Mano, Joao F.; Reis, Rui L.. "Cork extractives exhibit thermo-oxidative protection properties in polypropylene-cork composites and as direct additives for polypropylene". Polymer Degradation and Stability 116 (2015): 45-52. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355348800005&KeyUID=WOS:000355348800005.
    10.1016/j.polymdegradstab.2015.03.006
  56. Pires, R.A.; Abul-Haija, Y.M.; Costa, D.S.; Novoa-Carballal, R.; Reis, R.L.; Ulijn, R.V.; Pashkuleva, I.. "Controlling cancer cell fate using localized biocatalytic self-assembly of an aromatic carbohydrate amphiphile". Journal of the American Chemical Society 137 2 (2015): 576-579. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921457793&partnerID=MN8TOARS.
    10.1021/ja5111893
  57. Araújo, Ana R.; Pereira, David M.; Aroso, Ivo M.; Santos, Tânia; Batista, Maria T.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.; Pires, Ricardo A.. "Cork extracts reduce UV-mediated DNA fragmentation and cell death". RSC Advances 5 116 (2015): 96151-96157. http://dx.doi.org/10.1039/c5ra15712a.
    10.1039/c5ra15712a
  58. Monteiro, Nelson; Martins, Albino; Pires, Ricardo; Faria, Susana; Fonseca, Nuno A.; Moreira, Joao N.; Reisa, Rui L.; Neves, Nuno M.. "Immobilization of bioactive factor-loaded liposomes on the surface of electrospun nanofibers targeting tissue engineering". Biomaterials Science 2 9 (2014): 1195-1209. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000341519500006&KeyUID=WOS:000341519500006.
    10.1039/c4bm00069b
  59. Amorim, Sara; Martins, Albino; Neves, Nuno M.; Reis, Rui L.; Pires, Ricardo A.. "Hyaluronic acid/poly-L-lysine bilayered silica nanoparticles enhance the osteogenic differentiation of human mesenchymal stem cells". Journal of Materials Chemistry B 2 40 (2014): 6939-6946. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342994100005&KeyUID=WOS:000342994100005.
    10.1039/c4tb01071j
  60. Pires, Ricardo A; Leonor, Isabel B; Pashkuleva, Iva; Reis, Rui L. "Highlights from the latest articles in nanomedicine.". Nanomedicine (London, England) 9 5 (2014): 573-6. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:24827840&KeyUID=MEDLINE:24827840.
    10.2217/nnm.14.29
  61. Mestre, Ana S.; Pires, Ricardo A.; Aroso, Ivo; Fernandes, Emanuel M.; Pinto, Moises L.; Reis, Rui L.; Andrade, Marta A.; et al. "Activated carbons prepared from industrial pre-treated cork: Sustainable adsorbents for pharmaceutical compounds removal". Chemical Engineering Journal 253 (2014): 408-417. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340213600049&KeyUID=WOS:000340213600049.
    10.1016/j.cej.2014.05.051
  62. Nuno M Neves. "Anti-bacterial glass formulations for bone tissue engineering applications". Journal of Tissue Engineering and Regenerative Medicine (2014): https://publons.com/publon/4130669/.
  63. Fernandes, E.M.; Pires, R.A.; Mano, J.F.; Reis, R.L.. "Bionanocomposites from lignocellulosic resources: Properties, applications and future trends for their use in the biomedical field". Progress in Polymer Science 38 10-11 (2013): 1415-1441. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885019137&partnerID=MN8TOARS.
    10.1016/j.progpolymsci.2013.05.013
  64. Barros, A.A.A.; Alves, A.; Nunes, C.; Coimbra, M.A.; Pires, R.A.; Reis, R.L.. "Carboxymethylation of ulvan and chitosan and their use as polymeric components of bone cements". Acta Biomaterialia 9 11 (2013): 9086-9097. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885065626&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.06.036
  65. Gomes, F.O.; Pires, R.A.; Reis, R.L.. "Aluminum-free glass-ionomer bone cements with enhanced bioactivity and biodegradability". Materials Science and Engineering C 33 3 (2013): 1361-1370. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873404777&partnerID=MN8TOARS.
    10.1016/j.msec.2012.12.037
  66. Amorim, S.; Pires, R.A.; Da Costa, D.S.; Reis, R.L.; Pashkuleva, I.. "Interactions between exogenous FGF-2 and sulfonic groups: In situ characterization and impact on the morphology of human adipose-derived stem cells". Langmuir 29 25 (2013): 7983-7992. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879543962&partnerID=MN8TOARS.
    10.1021/la400871c
  67. Da Costa, D.S.; Pires, R.A.; Frias, A.M.; Reis, R.L.; Pashkuleva, I.. "Sulfonic groups induce formation of filopodia in mesenchymal stem cells". Journal of Materials Chemistry 22 15 (2012): 7172-7178. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858972552&partnerID=MN8TOARS.
    10.1039/c2jm15762d
  68. Pires, R.A.; Aroso, I.; Silva, S.P.; Mano, J.F.; Reis, R.L.. "Isolation of friedelin from black condensate of cork". Natural Product Communications 6 11 (2011): 1577-1579. http://www.scopus.com/inward/record.url?eid=2-s2.0-82455191744&partnerID=MN8TOARS.
  69. Pires, R.A.; Mano, J.F.; Reis, R.L.. "Surface properties of extracts from cork black condensate". Holzforschung 64 2 (2010): 217-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-76849098485&partnerID=MN8TOARS.
    10.1515/HF.2010.032
  70. Pires, R.A.; Abrahams, I.; Nunes, T.G.; Hawkes, G.E.. "The role of alumina in aluminoborosilicate glasses for use in glass-ionomer cements". Journal of Materials Chemistry 19 22 (2009): 3652-3660. http://www.scopus.com/inward/record.url?eid=2-s2.0-66249127217&partnerID=MN8TOARS.
    10.1039/b822285a
  71. Pires, R.A.; Nunes, T.G.; Abrahams, I.; Hawkes, G.E.. "The role of aluminium and silicon in the setting chemistry of glass ionomer cements". Journal of Materials Science: Materials in Medicine 19 4 (2008): 1687-1692. http://www.scopus.com/inward/record.url?eid=2-s2.0-40949116779&partnerID=MN8TOARS.
    10.1007/s10856-007-3251-y
  72. Pires, R.A.; Fernandez, C.; Nunes, T.G.. "Structural and spatially resolved studies on the hardening of a commercial resin-modified glass-ionomer cement". Journal of Materials Science: Materials in Medicine 18 5 (2007): 787-796. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248545242&partnerID=MN8TOARS.
    10.1007/s10856-006-0010-4
  73. Pires, R.A.; Abrahams, I.; Nunes, T.G.; Hawkes, G.E.. "Multinuclear magnetic resonance studies of borosilicate glasses for use in glass ionomer cements: Incorporation of CaO and Al2O3". Journal of Materials Chemistry 16 24 (2006): 2364-2373. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745023550&partnerID=MN8TOARS.
    10.1039/b601593j
  74. Pires, R.; Nunes, T.G.; Abrahams, I.; Hawkes, G.E.; Morais, C.M.; Fernandez, C.. "Stray-field imaging and multinuclear magnetic resonance spectroscopy studies on the setting of a commercial glass-ionomer cement". Journal of Materials Science: Materials in Medicine 15 3 (2004): 201-208. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642263902&partnerID=MN8TOARS.
    10.1023/B:JMSM.0000015479.65516.d0
  75. Pires, R.; Abrahams, I.; Nunes, T.G.; Hawkes, G.E.. "Non-random cation distribution in sodium-strontium-phosphate glasses". Journal of Non-Crystalline Solids 337 1 (2004): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442588520&partnerID=MN8TOARS.
    10.1016/j.jnoncrysol.2004.03.108
  76. Nunes, T.G.; Guillot, G.; Pereira, S.G.; Pires, R.. "1H stray-field long spin-echo trains and MRI: Novel studies on the photopolymerization of a commercial dental resin". Journal of Physics D: Applied Physics 35 11 (2002): 1251-1257. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037035997&partnerID=MN8TOARS.
    10.1088/0022-3727/35/11/323
  77. Nunes, T.G.; Pires, R.; Perdigão, J.; Amorim, A.; Polido, M.. "The study of a commercial dental resin by 1H stray-field magnetic resonance imaging". Polymer 42 19 (2001): 8051-8054. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035908170&partnerID=MN8TOARS.
    10.1016/S0032-3861(01)00296-8
Newspaper article
  1. Rodrigues, Ana J; Zille, Andrea; Lúcio, Joana; Castro, Nuno Filipe; Cerca, N.; Pires, Ricardo. "É necessário debater a política de emprego científico em Portugal", Público, 2023, Ciência e Ambiente, https://hdl.handle.net/1822/84907.
Thesis / Dissertation
  1. Fernandes, João Pedro Silva. "Antibacterial glass and glass-biodegradable matrix composites for bone tissue engineering". PhD, 2017. http://hdl.handle.net/1822/48683.

Intellectual property

Patent
  1. Pires, Ricardo A. 2014. "Stents based on natural polymers produced using clean technologies".
    Pending
  2. Pires, Ricardo A. 2014. "Extracto hidro-alcoólico de cortiça, processo para a sua preparação, formulações compreendendo o referido extracto e sua utilização".
    Pending
  3. Pires, Ricardo A. 2009. "Extraction and Purification of Friedelin".
    Pending
  4. Pires, Ricardo A. 2009. "Extraction of Polyol fractions from cork and cork-derived materials".
    Pending
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019 ECM mimics using modular minimalistic supramolecular systems TERMIS-EU 2019
(Rhodes, Greece)
2019 Hyaluronan-based 3D extracellular matrix model to study cancer progression TERMIS-EU 2019
(Rhodes, Greece)
2019 Natural aromatic small molecules redesign toxic soluble aß42 oligomers TERMIS-EU 2019
(Rhodes, Greece)
2019 Vescalagin/castalagin reduces Aß42 cytotoxicity through the modulation of its aggregation pathway Integrative Approaches to Protein Folding & Aggregation
(Lisboa, Portugal)
2019 Hyaluronan molecular weight regulates cancer cell migration and invasiveness 2nd FORECAST Workshop
(Porto, Portugal)
2019 Carbohydrate toolbox for the supramolecular (dis)assembly in nanomedicine GLUPOR 13
(Porto, Portugal)
2019 Biocatalytic self-assembly of supramolecular gels is controlled by the choice of the amphiphile regioisomer European Society for Biomaterials 2019
(Dresden, Germany)
2019 Glucose amphiphiles as metabolic inhibitors in cancer GLUPOR 13
(Porto, Portugal)
2019 Hyaluronan molecular weight regulates the dynamics of focal adhesions and cancer cell migration and invasiveness GLUPOR 13
(Porto, Portugal)
2019 Supramolecular inhibition of Aß42 intermediates by GlcN analogues GLUPOR 13
(Porto, Portugal)
2019 Carbohydrate stereoisomers self-assemble into supramolecular fibers with different helicity GLUPOR 13
(Porto, Portugal)
2018 Self-assembling carbohydrate amphiphiles for biomedical applications HUJI Nano-Center Annual Conference
(Jerusalem, Israel)
2018 Self-Assembly Glycan Amphiphiles for Biomedical Applications 3rd Asian University Symposium on Biomedical Engineerin
(South Korea)
2018 Co-assembly of peptide and carbohydrate amphiphiles to generate proteoglycan mimics 256th ACS National Meeting
(Boston, United States)
2018 Cork: a source of (bio)active compounds 3rd Chem2Nature Workshop

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2011 - 2017 Smart Materials Based on Polyester-Glass Composites for Bone Tissue Engineering
Co-supervisor
Materials Science and Engineering (PhD)
2012 - 2012 Carboxylated polysaccharides as the polymeric component of Glass-Ionomer Cements
Co-supervisor
Properties and Technology of Polymers (Master)
2010 - 2011 Bone cements – development of partially degradable ionomer cements
Co-supervisor
Characterization and Analytical Chemistry Techniques (Master)
Distinctions

Award

2021 Young Biophysicist Prize 2021 (Awarded to the PhD student Ana Rita Araújo - Supervised by Ricardo A. Pires)
2007 BES Inovação in the area of Forestry
Banco Espírito Santo e Comercial de Lisboa, Portugal