Curriculum Vitae
Elizabeth de Abreu Lopes
Elizabeth A. Lopes is a medicinal chemist with expertise in organic synthesis, analytical methods, molecular modeling, and
flow analysis. She holds a doctorate in Pharmacy from the University of Lisbon, where her research focused on developing novel
scaffolds and reactivators of p53 targeting cancer and malaria. Her work contributed to the discovery of potent bioactive
compounds and advanced strategies for hit-to-lead optimization.
With extensive experience across leading European laboratories, Elizabeth has excelled in designing innovative synthetic routes,
synthesizing and characterizing bioactive small molecules, and establishing structure-activity relationships to enhance drug
efficacy. Her computational chemistry expertise includes molecular docking, molecular dynamics, target fishing, and ADME prediction
using tools such as Schrodinger Suite, MOE, and PyMOL. She is also skilled in flow analysis techniques, having performed drug
quantification and pharmacokinetic studies using sequential injection lab-on-valve systems.
Elizabeth’s contributions extend beyond research; she has published over 10 peer-reviewed articles in high-impact journals,
presented her findings at more than 25 conferences, and received grants and awards. She has collaborated on interdisciplinary
projects, and worked across diverse fields, from antimalarial drug discovery to cancer therapies.
Identification
Personal identification
- Full name
- Elizabeth de Abreu Lopes
Citation names
- Lopes, Elizabeth A.
- Lopes, EA
- Elizabeth A. Lopes
Author identifiers
- Ciência ID
- E61C-F1AB-4D7D
- ORCID iD
- 0000-0001-5746-4058
- Google Scholar ID
- https://scholar.google.com/citations?user=Pepq6wYAAAAJ&hl=pt-PT&oi=ao
- Researcher Id
- AAG-3999-2021
- Scopus Author Id
- 57203321271
Email addresses
- elizabeth.lopes@edu.ulisboa.pt (Professional)
Websites
- https://www.linkedin.com/in/elizabeth-a-lopes-520b28105/ (Professional)
Knowledge fields
- Exact Sciences - Chemical Sciences - Organic Chemistry
- Exact Sciences - Computer and Information Sciences - Bioinformatics
- Exact Sciences - Chemical Sciences - Analytical Chemistry
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | |
Spanish; Castilian | Beginner (A1) | Beginner (A1) | Beginner (A1) | Beginner (A1) | |
French | Beginner (A1) | Beginner (A1) | Beginner (A1) | Beginner (A1) |
Education
Degree | Classification | |
---|---|---|
2018/10/01 - 2024/07/18
Concluded
|
Pharmacy (Doutoramento)
Major in Pharmaceutical and Therapeutic Chemistry
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Development of indole-based scaffolds for tackling Cancer and Malaria" (THESIS/DISSERTATION)
|
|
2015/09/01 - 2017/10/11
Concluded
|
Bioorganic Chemistry (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Spirooxadiazoline oxindoles: synthesis and evaluation of anticancer and antimalarial activities" (THESIS/DISSERTATION)
|
16 |
2011/09/01 - 2014/09/24
Concluded
|
Chemistry (Licenciatura)
Major in Chemistry
Universidade do Porto Faculdade de Ciências, Portugal
"Analytical characterization of photochemical degradation products of pieces of art " (THESIS/DISSERTATION)
|
17 |
Affiliation
Others
Category Host institution |
Employer | |
---|---|---|
2018/10/01 - 2024/07/18 | Ph.D student (supervisors Dr Maria M. M. Santos, Professor Maurizio Botta (until 2019) and Dr Mattia Mori (from 2020)) | iMed.ULisboa, Portugal |
iMed.ULisboa, Portugal | ||
2022/08/01 - 2022/08/26 | Scientific mission through DD4PPI project (PTDC/QUI-QOR/29664/2017) | Universität Wien Institut für Organische Chemie, Austria |
Universität Wien Institut für Organische Chemie, Austria | ||
2019/11/09 - 2019/12/11 | Scientific mission through bilateral project with Hungary (FCT-NKFIH) | Szegedi Tudományegyetem Gyógyszerésztudományi Kar, Hungary |
Szegedi Tudományegyetem Gyógyszerésztudományi Kar, Hungary | ||
2018/07/01 - 2018/09/30 | BI grant holder for Hovione (supervisor Dra Maria M. M. Santos) | iMed.ULisboa, Portugal |
iMed.ULisboa, Portugal | ||
2018/02/01 - 2018/04/30 | BI grant holder (supervisor Dr Maria M. M. Santos under the project PTCD/DTP-FTO/1981/2014 Targeting p53 Family Proteins: on the Route of New Anticancer Agents) | iMed.ULisboa, Portugal |
iMed.ULisboa, Portugal | ||
2017/11/01 - 2017/12/21 | Short Term Scientific Mission Cost Action CM1407 (In silico studies of indole derivatives, supervisor Professor Maurizio Botta and Dr Mattia Mori) | Università degli Studi di Siena Dipartimento di Biotecnologie Chimica e Farmacia, Italy |
Università degli Studi di Siena Dipartimento di Biotecnologie Chimica e Farmacia, Italy | ||
2016/09/05 - 2017/10/11 | Master student (supervisors Maria M. M. Santos and Lídia M. Gonçalves, classification 18 out of 20)) | iMed.ULisboa, Portugal |
iMed.ULisboa, Portugal | ||
2014/11/01 - 2015/05/02 | Erasmus+ internship (Pharmacokinetic study of the transport of a fluorescent marker through cell monolayer using SIA system, supervisors Dr Hana Sklenárová and Professor Peter Solich) | Univerzita Karlova Farmaceutická Fakulta v Hradci Králové, Czech Republic |
Univerzita Karlova Farmaceutická Fakulta v Hradci Králové, Czech Republic | ||
2014/02/01 - 2014/06/30 | Bachelor extracurricular project (PEEC) (Characterization of inorganic pigments, supervisor Dr Carlos Pereira, classification 18 out of 20) | Universidade do Porto Faculdade de Ciências, Portugal |
Universidade do Porto Faculdade de Ciências, Portugal | ||
2014/02/01 - 2014/06/30 | Bachelor curricular project for 20|21 (Characterization of products of photochemical degradation in pieces of contemporaneous art, supervisors Dr Carlos Pereira and Dr Luís Pinho) | Universidade do Porto Faculdade de Ciências, Portugal |
Universidade do Porto Faculdade de Ciências, Portugal (...) |
||
2012/10/01 - 2014/05/31 | Bachelor extracurricular IJUP project (Synthesis and application of novel molecularly imprinted material for determination of an aromatase inhibitor, supervisors Dr Manuel Azenha, Dr Marcela Segundo) | Universidade do Porto Faculdade de Ciências, Portugal |
Universidade do Porto Faculdade de Ciências, Portugal (...) |
Outputs
Publications
Book chapter |
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Conference poster |
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Journal article |
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Thesis / Dissertation |
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