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From 2006 to 2009, I completed my undergraduate studies in Cell and Molecular Biology (FCT-NOVA). Two years later, I obtained my MSc in Biotechnology (FCT/NOVA). In 2016, I received my PhD in Biochemistry under supervision of Profs. Teresa Santos-Silva and Maria João Romão (UCIBIO, FCT-NOVA) focusing on the structural/functional characterization of protein-ligand interactions of bioactive metal-based drugs - CORMs (CO-Releasing Molecules) and vanadium-based (6 papers/18 poster communications). I gained a strong X-ray crystallography background: protein-ligand crystallization (soaking/co-crystallization); in-house/synchrotron data collection; structure determination/ refinement. I also contacted with basic organometallic procedures and biological assays during short stays at C.C. Romão (ITQB-NOVA) and P.V.Baptista (FCT-NOVA) Labs. In 2016/2017, I undertook a postdoctoral position within the FCT project PTDC/QEQMED/1902/2014 with T. Santos-Silva aiming to nanofunctionalize CORM-3 with gold nanoparticles to fight rheumatoid arthritis. Parallelly, I also investigated a bioeconomy-related formate dehydrogenase enzyme for CO2 reduction. In 2017/2018, I moved to CQE/IST-UL with J.Pessoa to study putative anticancer V/Cu-complexes. I further developed my expertise in biophysical methods [Small-Angle X-ray Scattering (SAXS)/Thermal Shift Assay (TSA)/Microscale Thermophoresis (MST)]. Within my collaborations, I also have contacted with other characterization techniques as Electron Paramagnetic Resonance (EPR) and Circular Dichroism (CD). In 2019, on a part-time and volunteer-basis, I returned to UCIBIO where I have been involved in exciting drug design projects within new collaborations. With H.Terenzi (UFSC/Brazil), I started working on PtpA inhibitors, (co-)supervising 2MSc/3BSc students; with T.Santos-Silva, I started working on bacterial LCP protein family (biofilms formation implicated in antibiotic resistance); with L.Passarinha (UCIBIO; CICS/UBI), I was involved in the biophysical characterization of STEAP1 and COMT, 2 therapeutic protein targets in prostate cancer and Parkinson disease, respectively. In 2022, I started an independent collaboration with J.Dias (UCIBIO) on the structural/functional characterization of phage lysins to overcome antibiotic resistance. In addition, over the years, I spent several abroad periods (France, United Kingdom, Switzerland, Germany) improving my X-ray and SAXS data collection and analysis skills. To date, I have been member of 5 FCT financed projects (1.181.657¿) in addition to 2020-2023 UCIBIO and 2021-2025 i4HB funding projects (5.593.273€). I have 16 international peer reviewed publications (4 as 1st/corresponding author), 2 book chapters (both as corresponding author), 1 national peer reviewed paper, 1 national book chapter, 4 conference proceedings and 11 PDB entries [global Scopus metrics: H-index 11; 652 citations; average 36.22 citations per paper; average journal IF 7.3; most cited (153) paper: CCR, 2015, IF=24.8]. My work has been often presented in national/international structural biology/medicinal chemistry conferences (90 attendances: 24 oral/46 poster communications with 2 best poster awards) such as 1st-8th ENURS, EBSA2013, 47th Crystallographic School Erice, 6th ECCLS, 2014/2017/2021/2022/2023/2024 CCP4 Study Weekend and 7th ECBS/LS EuCHEMS. I supervised/co-supervised 6 BSc (2012/2013/2014/2018/2022/2023) and 3 MSc students (2015/2018/2019) tutoring over 40 other fellows and main argued 2 BSc projects (2018 and 2019). I supported Structural Biology classes (FCT-NOVA, FCS-UBI) and, in 2018, I co-organized the Workshop "X-ray Crystallography" (FCT-NOVA). I was still involved in different outreach activities (e.g., open day EXPO-FCT, 2014 International Year of Crystallography (FCT-NOVA), 2020 European Researchers Night) and I co-maintain a broad biology-based blog ("Science is Not Glamarous").
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Identification

Personal identification

Full name
Marino Filipe Alves dos Santos
Date of birth
1988/03/28
Gender
Male

Citation names

  • Marino F. A. Santos
  • MFA Santos
  • Marino Santos

Author identifiers

Ciência ID
E61F-DC83-9374
ORCID iD
0000-0002-8205-1041
Researcher Id
N-9093-2013
Scopus Author Id
55588796800

Email addresses

  • marino.fa.santos@gmail.com (Professional)
  • mf.santos@alumni.fct.unl.pt (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biophysics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2017/09 - 2018/06
Concluded
 Post-Doctoral Grant BPD/CQE-2017-029 (Pós-doutoramento)
Universidade de Lisboa Centro de Química Estrutural, Portugal
2016/09 - 2017/02
Concluded
 Project PTDC/QEQ-MED/1902/2014 (Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis) (Pós-doutoramento)
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2012/01/01 - 2016/07/11
Concluded
 Bioquímica (Doutoramento)
Major in Structural Biochemistry
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Structural and Functional studies on the Reactivity of CORMs with plasma proteins" (THESIS/DISSERTATION)
 Approved by unanimity
2014/10 - 2014/10
Concluded
 BAG Training ESRF (Postgraduate Certificate)
European Synchrotron Radiation Facility (ESRF), France
2012/07/01 - 2012/10/15
Concluded
 Postgraduate Studies in Hands-on Course: From proteomics to proteins (Pós-Graduação)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 19 (out of 20)
2009/09/15 - 2011/10/26
Concluded
 Biotecnologia (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Interacções de proteínas do plasma com potenciais fármacos: estudos 3D a nível molecular" (THESIS/DISSERTATION)
 18 (out of 20)
2006/09/15 - 2009/07/17
Concluded
 Biologia Celular e Molecular (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 15 (out 20)
2003/09/18 - 2006/07/31
Concluded
 - (Ensino secundário)
Major in Agrupamento Geral - Científico-Natural
Escola Secundária Daniel Sampaio, Portugal
 17 (out of 20)
Affiliation

Others

Category
Host institution 		Employer
2019/01/01 - Current Visiting Post-Doctoral Fellow (volunteer) at the Laboratory of Macromolecular Crystallography REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2019/01/01 - Current Volunteer at a Wholesaling Small Company Batista Santos e Santos Lda, Portugal
2017/09/01 - 2018/06/29 Post-Doctoral Fellow (BPD/CQE-2017-029) under supervision of João Costa Pessoa Universidade de Lisboa Centro de Química Estrutural, Portugal
Universidade de Lisboa Centro de Química Estrutural, Portugal
2018/05 - 2018/06 Short stay (1 week) - X-ray and SAXS data collection Deutsches Elektronen-Synchrotron, Germany
Deutsches Elektronen-Synchrotron, Germany
2012/10 - 2018/04 Ten short stays (3/4 days) - X-ray and SAXS data collection European Synchrotron Radiation Facility (ESRF), France
European Synchrotron Radiation Facility (ESRF), France
2016/09/01 - 2017/07/31 Post-doctoral Fellow under the project PTDC/QEQ-MED/1902/2014 (Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2012/01/01 - 2016/07/11 PhD student in Biochemistry (Structural Biochemistry) with the project "Structural and Functional studies on the Reactivity of CORMs with plasma proteins" REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/03 - 2015/07 Visiting Fellow at Nanomedicine@FCT/UNL Lab under supervision of Pedro V. Baptista and Alexandra R. Fernandes REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2013/12 - 2015/02 Two short stays (5 days) - X-ray data collection Swiss Light Source - SLS, Switzerland
Swiss Light Source - SLS, Switzerland
2014/03 - 2014/11 Two short stays (5 days) - X-ray data collection Synchrotron SOLEIL, France
Synchrotron SOLEIL, France
2013/10 - 2013/10 Short stays (4 days) - X-ray data collection Diamond Light Source Ltd, United Kingdom
Diamond Light Source Ltd, United Kingdom
2013/02/01 - 2013/02/28 Visiting Fellow at Organometallic Chemistry Lab under supervision of Carlos C. Romão Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010/09/06 - 2011/10/26 Master's Dissertation Project in Biotechnology: "Interacções de proteínas do plasma com potenciais fármacos: estudos 3D a nível molecular" REQUIMTE, Portugal
REQUIMTE, Portugal
2008/10/15 - 2009/10/15 Integration into Research Grant: "Interacções proteína-ligando e alterações conformacionais de proteínas em solução: Um estudo por RMN" Supervisors: Anjos Macedo, Jorge Caldeira Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
REQUIMTE, Portugal
Projects

Grant

Designation Funders
2017/09 - 2018/06 Centro de Química Estrutural
BPD/CQE-2017-029
Post-doc Fellow
Universidade de Lisboa Centro de Química Estrutural, Portugal
Concluded
2016/09 - 2017/02 Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis
PTDC/QEQ-MED/1902/2014
Post-doc Fellow
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Concluded
2012/01 - 2015/12 Structural and Functional studies on the Reactivity of CORMs with plasma proteins
SFRH/BD/77894/2011
PhD Student Fellow
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
2008/10 - 2009/10 Interacções proteína-ligando e alterações conformacionais de proteínas em solução: Um estudo por RMN
-
Integration into Research Grant Fellow
REQUIMTE, Portugal
Concluded

Contract

Designation Funders
2021/01/01 - 2025/12/31 Instituto para a Saúde e a Bioeconomia
LA/P/0140/2020
10.54499/LA/P/0140/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Unidade de Ciências Biomoleculares Aplicadas
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/01/01 - 2023/12/31 Unidade de Ciências Biomoleculares Aplicadas
UIDP/04378/2020
10.54499/UIDP/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/01 - 2018/12 Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis
Provided by PTCRIS: 140528
Other
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2016 - 2017 Reduction of CO2 for sustainable biofuel production
PTDC/BBB-EBB/2723/2014
Post-doc
Concluded
2013/07 - 2016/06 Modern Structural Biology: Resources for the advancement of in-house X-ray Crystallography
Provided by PTCRIS: 125363
Other
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2012/03 - 2015/08 Protein interaction with CO Releasing Molecules (CORM)
Provided by PTCRIS: 117799
PhD Student Fellow
Fundação para a Ciência e a Tecnologia, I.P.
2012/02 - 2015/07 Mammalian and Bacterial Aldehyde Oxidases: Structure, mechanism and insights into cofactor binding and protein maturation
Provided by PTCRIS: 118377
PhD Student Fellow
Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Book chapter
  1. Engrola, Filipa S. S.; Paquete-Ferreira, João; Santos-Silva, Teresa; Correia, Márcia A. S.; Leisico, Francisco; Marino F. A. Santos. Corresponding author: Marino F. A. Santos. "Screening of Buffers and Additives for Protein Stabilization by Thermal Shift Assay: A Practical Approach". In Advanced Methods in Structural Biology, 199-213. Springer US, 2023.
    Published • 10.1007/978-1-0716-3147-8_11
  2. Paquete-Ferreira, João; Leisico, Francisco; Correia, Márcia A. S.; Engrola, Filipa S. S.; Santos-Silva, Teresa; Marino F. A. Santos. Corresponding author: Marino F. A. Santos. "Using Small-angle X-ray Scattering to Characterize Biological Systems: A General Overview and Practical Tips". In Advanced Methods in Structural Biology, 381-403. Springer US, 2023.
    Published • 10.1007/978-1-0716-3147-8_22
  3. Marino F. A. Santos; Rui M. C. Portela; Tânia Leandro; Tânia Perestrelo. "Darwin em Londres: 1836-1842; Notebooks de Darwin". In O Percurso até à Publicação da Origem das Espécies, 65-85. Caparica, Portugal: Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2009.
Conference paper
  1. Marino F. A. Santos; Andreia C. P. Fernandes; Isabel Correia; Eugenio Garribba; James Doutch; Teresa Santos Silva; João Costa Pessoa. "The world of protein-ligand interactions: Computational, biophysical and structural characterization of vanadium-based complexes". Paper presented in International School of Chemistry: Chemistry for everyday life, Camerino, 2020.
    Published
  2. Marino F. A. Santos; João Costa Pessoa; Isabel Correia; Nádia Ribeiro; Cristina Matos; Patrique Nunes; Fernanda Marques; et al. "Evaluation and comparison of Cu-, V-, Zn and Fe-complexes containing bipy or phen as ligands as anticancer agents,". Paper presented in 18th ICBIC18 - International Conference on Biological Inorganic Chemistry, Florianópolis, 2017.
  3. Marino F. A. Santos; Ana R. Oliveira; Somnath Roy; Maria João Romão; João Costa Pessoa; Teresa Santos-Silva. "Vanadium compounds as prospective therapeutics: X-ray structure of protein adducts". Paper presented in EBSA2013 - 9th EBSA European Biophysics Congress, Lisboa, 2013.
    Published
  4. Teresa Santos-Silva; Abhik Mukhopadhyay; Marino F. A. Santos; João D. Seixas; Ana C. Coelho; Patrícia M. Reis; Maria João Romão; Carlos C. Romão. "How CO releasing molecules CO-RMs interact with proteins". Paper presented in International Symposia on Metal Complexes (ISMEC 2012), Lisboa, 2012.
    Published
Conference poster
  1. Marino F. A. Santos; Giuseppe Sciortino; Isabel Correia; Andreia C. P. Fernandes; Teresa Santos-Silva; Eugenio Garribba; João Costa Pessoa. "Exploring the oxidation state of V-based complexes bound to proteins: An X-ray and Theoretical Characterization". Paper presented in 2022 SSRL/LCLS Users' Meeting, 2022.
  2. Marino F. A. Santos; Isabel Correia; James Doutch; Ielyzaveta Chorna; Isabel Cavaco; Somnath Roy; Maxim L. Kuznetsov; et al. "Bis(acetylacetonato)oxidovanadium(IV) and human serum transferrin - A SAXS, contribution". Paper presented in EMBL Hamburg P12 Virtual User Meeting, 2021.
  3. Marino F. A. Santos; Isabel Correia; James Doutch; Ielyzaveta Chorna; Isabel Cavaco; Somnath Roy; Maxim L. Kuznetsov; et al. "Bis(acetylacetonato)oxidovanadium(IV) and human serum transferrin - A SAXS, Circular Dichroism and MALDI-TOF characterization". Paper presented in S4SAS Conference 2021, 2021.
  4. Jorge Barroca-Ferreira; Marino F. A. Santos; Cláudio J. Maia; Teresa Santos-Silva; Luís A. Passarinha. "A Molecular Perspective on the Bio-Structural Properties of the Human Native Six-Transmembrane Epithelial Antigen of the Prostate 1 (STEAP1)". Paper presented in 24th Meeting of the International Society for Molecular Recognition, 2021.
  5. João Paquete-Ferreira; Jayaraman Muthukumaran; João Ramos; Filipe Freire; Marino F. A. Santos; Márcia A. S. Correia; Maria João Romão; Alexandra R. Fernandes; Teresa Santos-Silva. "Might LCP Proteins Represent the Key to Biofilm Inhibition". Paper presented in PDB50 - Symposium celebrating the 50th anniversary of the Protein Data Bank, 2021.
  6. Marino F. A. Santos; Inês Mendonça-Martins; Luís R. Raposo; Rita Mendes; Joana Marques; Carlos C. Romão; Maria João Romão; et al. "Improving the Anti-inflammatory Response via Gold Nanoparticle Vectorization of CO-Releasing Molecules". Paper presented in EuroNanoForum2021, 2021.
  7. Marino F. A. Santos; James Doutch; Isabel Correia; Andreia C.P. Fernandes; Teresa Santos-Silva; João Costa Pessoa. "Using structural tools to unveil the interactions between vanadium-based complexes and proteins". Paper presented in European Chemical Biology Symposium (ECBS2021), 2021.
  8. João Paquete-Ferreira; Jayaraman Muthukumaran; João Ramos; Filipe Freire; Marino F. A. Santos; Márcia A. S. Correia; Maria João Romão; Alexandra R. Fernandes; Teresa Santos-Silva. "Targeting Besides the Peptidoglycan, a Novel Approach for the Development of New Antimicrobial Agents". Paper presented in European Chemical Biology Symposium (ECBS2021), 2021.
  9. Marino F. A. Santos; Isabel Correia; James Doutch; Ielyzaveta Chorna; Isabel Cavaco; Somnath Roy; Maxim L. Kuznetsov; et al. "Biophysical insights on the interaction of bis(acetylacetonato)oxidovanadium(IV) with human serum transferrin". Paper presented in 25th Annual Sealy Center Structural Biology Symposium, 2021.
  10. João Paquete-Ferreira; Jayaraman Muthukumaran; João Ramos; Filipe Freire; Marino F. A. Santos; Márcia A. S. Correia; Maria João Romão; Alexandra R. Fernandes; Teresa Santos-Silva. "Crystal Structure vs in Solution: Unravelling the Conformations of an LCP Protein from a Biofilm Producer". Paper presented in ESRF Virtual User Meeting 2021, 2021.
  11. Marino F. A. Santos; Andreia C. P. Fernandes; Isabel Correia; James Doutch; Teresa Santos-Silva; João Costa Pessoa. "Synchrotron-based characterization of Transferrin and HEWL with vanadium-based compounds: A solution and crystal study". Paper presented in ESRF Virtual User Meeting 2021, 2021.
  12. Marino F. A. Santos; James Doutch; Andreia C. P. Fernandes; Isabel Correia; João Costa Pessoa; Teresa Santos-Silva. "Organic and inorganic vanadium-based complexes interactions with Human Serum Transferrin and Hen Egg White Lysozyme – A combined SAXS and crystallographic study". Paper presented in EMBL Hamburg P12 Virtual User Meeting, 2020.
  13. Marino F. A. Santos; Andreia C. P. Fernandes; Isabel Correia; James Doutch; Teresa Santos-Silva; João Costa Pessoa. "Synchrotron-based characterization of proteins complexed with vanadium-based compounds". Paper presented in 2020 Virtual Stanford Synchrotron Radiation Lightsource (SSRL)/Linac Coherent Light Source (LCLS) Users' Meeting, 2020.
  14. Marino F. A. Santos; Andreia C. P. Fernandes; James Doutch; Isabel Correia; Teresa Santos-Silva; João Costa Pessoa. "A Journey into the Structural and Biophysical Characterization of Vanadium-based Compounds". Paper presented in CICS-UBI Symposium 2020, 2020.
  15. Andreia C. P. Fernandes; Marino F. A. Santos; Francisco Leisico; Maria M. B. Marques; Hernán Terenzi; Teresa Santos-Silva. "A Structure-based Drug Design Approach to Fight Tuberculosis - Developing New PtpA Inhibitors". Paper presented in CICS-UBI Symposium 2020, 2020.
  16. Marino F. A. Santos; Andreia C. P. Fernandes; James Doutch; Isabel Correia; Teresa Santos-Silva; João Costa Pessoa. "SAXS and X-ray crystallography hints to depict how V(IV)OSO4 and NaV(V)O3 complexes interact with transferrin and lysozyme". Paper presented in S4SAS Conference 2020, 2020.
  17. Andreia C. P. Fernandes; Marino F. A. Santos; Francisco Leisico; Jayaraman Muthukumaran; Hernán Terenzi; Maria M. B. Marques; Teresa Santos-Silva. "A Structure-based Drug Design Approach to Fight Tuberculosis - Developing New Inhibitors Targeting the Phosphatase PtpA". Paper presented in 11th AIMS (Annual International (bio)Medical Students) Meeting, Aula Magna of University of Lisbon, Lisboa, Portugal (postponed due to the COVID-19 outbreak) ), 2020.
  18. Andreia C. P. Fernandes; Marino F. A. Santos; Francisco Leisico; Jayaraman Muthukumaran; Maria M. B. Marques; Hernán Terenzi; Teresa Santos-Silva. "Structural and Functional Characterization of a New Bacterial Target Against Tuberculosis: The Phosphatase PtpA". Paper presented in iMed Conference 11.0, Lisboa, Portugal, 2019.
  19. Cristiano Mota; Ana R. Oliveira; Marino F. A. Santos; Diana Gesto; Teresa Santos-Silva; Inês A. Cardoso Pereira; Maria João Romão. "The crystal stucture of an oxygen-tolerant and highly efficient W-Formate Dehydrogenase". Paper presented in MoTEC2019 - XI Molybdenum & Tungsten Enzyme Conference 2019, Potsdam, Germany, 2019.
    10.1109/meta.2008.4723530
  20. Joana J. F. Gonçalves; Francisco Leisico; Marino F. A. Santos; Hernán Terenzi; Teresa Santos-Silva. "Structural and biophysical characterization of PtpA-inhibitors complexes: a possible target against tuberculosis". Paper presented in 1st Meeting of Young Biophysicists, ITQB-UNL, Oeiras, Portugal, 2018.
  21. Marino F. A. Santos; James Doutch; Henrique Amado; Isabel Correia; João Costa Pessoa; Teresa Santos-Silva. "Structural and biophysical characterization of protein-vanadium interactions by X-ray crystallography and SAXS". Paper presented in 1st Meeting of Young Biophysicists, ITQB_UNL, Oeiras, Portugal, 2018.
  22. Joana J. F. Gonçalves; Francisco Leisico; Marino F. A. Santos; Hernán Terenzi; Teresa Santos-Silva. "Structural and functional studies of a new class of Mycobacterium tuberculosis inhibitors". Paper presented in 7th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), FCT-UNL, Caparica, Portugal, 2018.
  23. Marino F. A. Santos; Henrique Amado; James Doutch; Isabel Correia; Teresa Santos-Silva; João Costa Pessoa. "New structural insights on protein-VIVOSO4 and protein-NaVVO3 interactions revealed by X-ray crystallography and SAXS". Paper presented in 7th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), FCT-NOVA, Caparica, Portugal, 2018.
  24. Marino F. A. Santos; Isabel Correia; James Doutch; Ielyzaveta Chorna; Isabel Cavaco; Somnath Roy; Maxim L. Kuznetsov; et al. "Using Synchrotron radiation to characterize the interactions of VIVO(acac)2 with human serum transferrin – A biophysical study". Paper presented in 6th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), LNEG, Alfragide, Portugal, 2017.
    10.1158/1538-7445.am2011-lb-201
  25. Rita Mendes; Ana R. Oliveira; Marino F. A. Santos; Maria João Romão; Pedro Viana Baptista; Alexandra R. Fernandes; Carlos C. Romão; Teresa Santos-Silva. "Can nanoparticles be used for efficient CO delivery during inflammation?". Paper presented in XVI DESY Research Course Nanoscience at Modern X-ray Sources, DESY, Hamburg, Germany, 2017.
  26. Marino F. A. Santos; Carlos C. Romão; João Costa Pessoa; Maria João Romão; Teresa Santos-Silva. "A journey into the world of metal-based drugs – New findings on CORMs and vanadium complexes revealed by X-ray crystallography". Paper presented in Encontro Ciência2016, Centro de Congressos de Lisboa, Portugal, 2016.
  27. Marino F. A. Santos; Ana C. Coelho; Marta F. M. Vieira; Maria João Romão; Carlos C. Romão; Teresa Santos-Silva. "Iridium- and platinum-based CORMs as putative drugs – Synthesis, FTIR characterization and structural characterization of protein adducts". Paper presented in 5th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), ITQB/UNL, Oeiras, Portugal, 2016.
  28. Marino F. A. Santos; Ana R. Oliveira; Isabel Correia; Eugenio Garribba; João Costa Pessoa; Teresa Santos-Silva. "Structural Characterization of VIVO(carrier)2-Protein Adducts – New perspectives on Vanadium interactions with Lysozyme, Trypsin and Transferrin". Paper presented in 2nd Integrative Structural Biology tools for the study of protein-ligand interactions (ISBio), FCT/UNL, Caparica, Portugal, 2015.
  29. Marino F. A. Santos; Ana R. Oliveira; Isabel Correia; Eugenio Garribba; João Costa Pessoa; Teresa Santos-Silva. "Structural Characterization of VIVO(carrier)2-Protein Adducts – New perspectives on Vanadium interactions with Lysozyme, Trypsin and Transferrin". Paper presented in 6th European Conference on Chemistry in Life Sciences (6th ECCLS), Rectorate UNL, Lisboa, Portugal, 2015.
  30. Ana R. Oliveira; Marino F. A. Santos; João Costa Pessoa; Teresa Santos-Silva. "VIVO(pic)2-Protein Adducts – Structure and Function of Potential Inhibitors". Paper presented in 4th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), FCT/UC, Coimbra, Portugal, 2015.
  31. Marino F. A. Santos; João D. Seixas; Abhik Mukhopadhyay; Ana C. Coelho; Patrícia M. Reis; Luís F. Veiros; Ana R. Marques; et al. "Structural Characterization of Ru(CO)3Cl2L CORMs with Lysozyme – New insights into the CO releasing mechanism". Paper presented in 4th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), FCT/UC, Coimbra, Portugal, 2015.
    10.1109/oceansap.2016.7485624
  32. Marino F. A. Santos; Isabel Correia; Ana R. Oliveira; Eugenio Garribba; João Costa Pessoa; Teresa Santos-Silva. "Structural Characterization of a VIVO(pic)2 Lysozyme Adduct – New Insights on Vanadium Complexes as Potential Therapeutics". Paper presented in 47th Crystallographic Course: Structural Basis of Pharmacology, Erice, Italy, 2014.
  33. João D. Seixas; Abhik Mukhopadhyay; Ana Catarina Coelho; Marino F. A. Santos; Patrícia M. Reis; Gonçalo J. L. Bernardes; Ana M. Gonçalves; et al. "The Reactivity of [RuCl2(CO)3L] Complexes in Aqueous Media and with Proteins". Paper presented in 10th Inorganic Chemistry Conference, Hotel Costa da Caparica, Caparica, Portugal, 2014.
  34. Marino F. A. Santos; Isabel Correia; Ana R. Oliveira; Eugenio Garribba; João Costa Pessoa; Teresa Santos-Silva. "Structural Characterization of a VIVO(pic)2 Lysozyme Adduct – New Insights on Vanadium Complexes as Potential Therapeutics". Paper presented in 3rd Meeting of the Synchrotron Radiation Users from Portugal (ENURS), CDRSP/IPL, Marinha Grande, Portugal, 2014.
  35. Marino F. A. Santos; Ana R. Oliveira; Somnath Roy; Maria João Romão; João Costa Pessoa; Teresa Santos-Silva. "Vanadium compounds as prospective therapeutics: X-ray structure of protein adducts". Paper presented in ENEBIOQ VII, FCT/UNL, Caparica, Portugal, 2014.
  36. Marino F. A. Santos; Ana R. Oliveira; Somnath Roy; Maria João Romão; João Costa Pessoa; Teresa Santos-Silva. "Vanadium compounds as prospective therapeutics: X-ray structure of protein adducts". Paper presented in EBSA2013, Pavilhão Atlântico, Lisboa, Portugal, 2013.
  37. Teresa Santos-Silva; Marino F. A. Santos; Ana R. Oliveira; Somnath Roy; Maria João Romão; João Costa Pessoa. "Vanadium compounds as prospective therapeutics: X-ray structure of protein adducts". Paper presented in Drug Discovery & Therapy World Congress 2013, Boston USA, 2013.
  38. Marino F. A. Santos; João D. Seixas; Ana C. Coelho; Abhik Mukhopadhyay; Patrícia M. Reis; Maria João Romão; Carlos C. Romão; Teresa Santos-Silva. "X-ray Characterization of Lysozyme coordinated to a ruthenium CORM". Paper presented in 2nd Meeting of the Synchrotron Radiation Users from Portugal (ENURS), Pavilhão do Conhecimento, Lisboa, Portugal, 2013.
  39. Marino F. A. Santos; João D. Seixas; Ana C. Coelho; Abhik Mukhopadhyay; Patrícia M. Reis; Maria João Romão; Carlos C. Romão; Teresa Santos-Silva. "X-ray Characterization of Lysozyme coordinated to a ruthenium CORM". Paper presented in BioCrys2012, ITQB/UNL, Oeiras, Portugal., 2012.
    10.1109/melcon.2012.6196578
  40. Ana C. Coelho; Gonçalo J.L. Bernardes; João D. Seixas; Marino F. A. Santos; Abhik Mukhopadhyay; Maria João Romão; Teresa Santos-Silva; Carlos C. Romão. "Synthesis and Characterization of Novel Ruthenium Based CORM Candidates". Paper presented in 25th International Symposium on Organometallic Chemistry, Lisboa, Portugal., 2012.
    10.1117/12.477347
  41. Carlos C. Romão; Teresa Santos-Silva; Abhik Mukhopadhyay; Marino F. A. Santos; João D. Seixas; Patrícia M. Reis; Ana C. Coelho,; Maria João Romão. "Exploring the Interaction of CO-Releasing Molecules with Proteins". Paper presented in 1st Whole Action Meeting, COST CM1105, Functional Metal Complexes that Bind to Biomolecules, Granada, Spain., 2012.
  42. Marino F. A. Santos; Abhik Mukhopadhyay; João D. Seixas; Maria João Romão; Carlos C. Romão; Teresa Santos-Silva. "Structural Characterization of a potential CORM coordinated to Lysozyme". Paper presented in V Hands-on Course "From Proteomics to Proteins", FCT/UNL, Caparica, Portugal, 2012.
  43. Marino F. A. Santos; Abhik Mukhopadhyay; João D. Seixas; Maria João Romão; Carlos C. Romão; Teresa Santos-Silva. "Structural Characterization of a potential CORM coordinated to Lysozyme". Paper presented in 1st Meeting of the Synchrotron Radiation Users from Portugal (ENURS), FCT/UNL, Caparica, Portugal, 2012.
  44. Marino F. A. Santos; Rui M. C. Portela; Tânia Leandro; Tânia Perestrelo. "Darwin em Londres: 1836-1842". Paper presented in Exposição "A rEvolução Darwiniana", FCT/UNL, Caparica, Portugal., 2009.
  45. Marino F. A. Santos; Rui M. C. Portela; Tânia Leandro; Tânia Perestrelo. "Notebooks de Darwin". Paper presented in Exposição "A rEvolução Darwiniana", FCT/UNL, Caparica, Portugal., 2009.
  46. Marino F. A. Santos; Rui M. C. Portela; Tânia Perestrelo. "Nicotina - Uma visão toxicológica". Paper presented in Student Meeting - Molecular Toxicology Class, 2008.
Journal article
  1. Marino F. A. Santos; João Costa Pessoa. Corresponding author: Marino F. A. Santos. "Interaction of Vanadium Complexes with Proteins: Revisiting the Reported Structures in the Protein Data Bank (PDB) since 2015". Molecules (2023): https://www.mdpi.com/1420-3049/28/18/6538.
    10.3390/molecules28186538
  2. Ana M. Gonçalves; Augusto Q. Pedro; Diana M. Oliveira; Adriana E. Oliveira; Marino F. A. Santos; Márcia A. S. Correia; João Queiroz; et al. "Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-Methyltransferase". International Journal of Molecular Sciences 23 20 (2022): 232012298. https://www.mdpi.com/1422-0067/23/20/12298 (2022 Impact Factor: 5.60; Citations: 2).
    Published • 10.3390/ijms232012298
  3. Jorge Barroca-Ferreira; Ana M. Gonçalves; Marino F. A. Santos; Teresa Santos-Silva; Cláudio J. Maia; Luís A. Passarinha. "A chromatographic network for the purification of detergent-solubilized six-transmembrane epithelial antigen of the prostate 1 from Komagataella pastoris mini-bioreactor lysates". Journal of Chromatography A 1685 (2022): 463576. https://www.sciencedirect.com/science/article/pii/S0021967322007671 (2022 Impact Factor: 4.1; Citations: 3)..
    Open access • Published
  4. Santos, Marino F. A.; Sciortino, Giuseppe; Correia, Isabel; Fernandes, Andreia C. P.; Santos-Silva, Teresa; Pisanu, Federico; Garribba, Eugenio; Pessoa, João Costa. "Binding of VIVO2+, VIVOL+, VIVOL2 and VVO2L moieties to proteins: X-ray/theoretical characterization and biological implications". Chemistry ¿ A European Journal 28 40 (2022): e202200105. https://doi.org/10.1002/chem.202200105 (2022 Impact Factor: 4.30; Citations: 8)..
    Published • 10.1002/chem.202200105
  5. Pessoa, João Costa; Santos, Marino F.A.; Correia, Isabel; Sanna, Daniele; Sciortino, Giuseppe; Garribba, Eugenio. "Binding of vanadium ions and complexes to proteins and enzymes in aqueous solution". Coordination Chemistry Reviews 449 (2021): 214192. http://dx.doi.org/10.1016/j.ccr.2021.214192 (2022 Impact Factor: 24.80; Citations: 36).
    10.1016/j.ccr.2021.214192
  6. Barroca-Ferreira, Jorge; Cruz-Vicente, Pedro; Santos, Marino F. A.; Rocha, Sandra M.; Santos-Silva, Teresa; Maia, Cláudio J.; Passarinha, Luís A.. "Enhanced Stability of Detergent-Free Human Native STEAP1 Protein from Neoplastic Prostate Cancer Cells upon an Innovative Isolation Procedure". International Journal of Molecular Sciences 22 18 (2021): 10012. http://dx.doi.org/10.3390/ijms221810012 (2022 Impact Factor: 5.60; Citations: 5).
    10.3390/ijms221810012
  7. Ana Rita Oliveira; Cristiano Mota; Cláudia Mourato; Renato M. Domingos; Marino F. A. Santos; Diana Gesto; Bruno Guigliarelli; et al. "Toward the Mechanistic Understanding of Enzymatic CO2 Reduction". ACS Catalysis 10 6 (2020): 3844-3856. https://doi.org/10.1021%2Facscatal.0c00086 (2022 Impact Factor: 12.90; 67 citations).
    10.1021/acscatal.0c00086
  8. Alexandra R. Fernandes; Inês Mendonça-Martins; Marino F. A. Santos; Luís R. Raposo; Rita Mendes; Joana Marques; Carlos C. Romão; et al. "Improving the Anti-inflammatory Response via Gold Nanoparticle Vectorization of CO-Releasing Molecules". ACS Biomaterials Science & Engineering 6 2 (2020): 1090-1101. https://doi.org/10.1021%2Facsbiomaterials.9b01936 (2022 Impact Factor: 5.70; Citations: 16).
    10.1021/acsbiomaterials.9b01936
  9. Cristina G. Azevedo; Isabel Correia; Margarida M.C. dos Santos; Marino F.A. Santos; Teresa Santos-Silva; James Doutch; Luz Fernandes; et al. "Binding of vanadium to human serum transferrin - voltammetric and spectrometric studies". Journal of Inorganic Biochemistry 180 (2018): 211-221. https://doi.org/10.1016%2Fj.jinorgbio.2017.12.012 (2022 Impact Factor: 3.90; Citations: 24).
    Published • 10.1016/j.jinorgbio.2017.12.012
  10. Isabel Correia; Ielyzaveta Chorna; Isabel Cavaco; Somnath Roy; Maxim L. Kuznetsov; Nádia Ribeiro; Gonçalo Justino; et al. "Interaction of [VIVO(acac)2] with Human Serum Transferrin and Albumin". Chemistry - An Asian Journal 12 16 (2017): 2062-2084. https://doi.org/10.1002%2Fasia.201700469 (2022 Impact Factor: 4.10; Citations: 38).
    10.1002/asia.201700469
  11. João Costa Pessoa; Eugenio Garribba; Marino F.A. Santos; Teresa Santos-Silva. "Vanadium and proteins: Uptake, transport, structure, activity and function". Coordination Chemistry Reviews 301-302 (2015): 49-86. http://dx.doi.org/10.1016/j.ccr.2015.03.016 (2022 Impact Factor: 24.80; Citations: 150).
    10.1016/j.ccr.2015.03.016
  12. João D. Seixas; Marino F. A. Santos; Abhik Mukhopadhyay; Ana C. Coelho; Patrícia M. Reis; Luís F. Veiros; Ana R. Marques; et al. "A contribution to the rational design of Ru(CO) 3 Cl 2 L complexes for in vivo delivery of CO". Dalton Transactions 44 11 (2015): 5058-5075. http://dx.doi.org/10.1039/c4dt02966f (2022 Impact Factor: 4.00; Citations: 68).
    10.1039/c4dt02966f
  13. João Costa Pessoa; Gisela Gonçalves; Somnath Roy; Isabel Correia; Sameena Mehtab; Marino F.A. Santos; Teresa Santos-Silva. "New insights on vanadium binding to human serum transferrin". Inorganica Chimica Acta 420 (2014): 60-68. http://dx.doi.org/10.1016/j.ica.2013.11.025 (2022 Impact Factor: 2.80; Citations: 47).
    10.1016/j.ica.2013.11.025
  14. Marino F. A. Santos; Isabel Correia; Ana R. Oliveira; Eugenio Garribba; João Costa Pessoa; Teresa Santos-Silva. "Vanadium Complexes as Prospective Therapeutics: Structural Characterization of a V IV Lysozyme Adduct". European Journal of Inorganic Chemistry 2014 21 (2014): 3293-3297. http://dx.doi.org/10.1002/ejic.201402408 (2022 Impact Factor: 2.30; Citations: 54).
    10.1002/ejic.201402408
  15. Sameena Mehtab; Gisela Gonçalves; Somnath Roy; Ana Isabel Tomaz; Teresa Santos-Silva; Marino F.A. Santos; Maria J. Romão; et al. "Interaction of vanadium(IV) with human serum apo-transferrin". Journal of Inorganic Biochemistry 121 (2013): 187-195. http://dx.doi.org/10.1016/j.jinorgbio.2012.12.020 (2022 Impact Factor: 3.90; Citations: 72).
    10.1016/j.jinorgbio.2012.12.020
  16. M.F.A. Santos; J.D. Seixas; A.C. Coelho; A. Mukhopadhyay; P.M. Reis; M.J. Romão; C.C. Romão; T. Santos-Silva. "New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme". Journal of Inorganic Biochemistry 117 (2012): 285-291. http://dx.doi.org/10.1016/j.jinorgbio.2012.06.018 (2022 Impact Factor: 3.90; Citations: 53).
    10.1016/j.jinorgbio.2012.06.018
Journal issue
  1. Marino F. A. Santos; Luís A. Passarinha. "Structural and Other Proteomics Approaches in Drug Discovery". Pharmaceuticals (2023): https://www.mdpi.com/journal/pharmaceuticals/special_issues/5162K897KC.
    Under revision • Invited editor
Magazine article
  1. Maria João Romão; Teresa Santos-Silva; Isabel Bento; Filipe Freire; Marino F. A. Santos; Ana Luísa Carvalho. "Marcos Históricos em Cristalografia", Química - Boletim da Sociedade Portuguesa de Química, 2015, https://www.spq.pt/magazines/BSPQuimica/668.
Online resource
  1. Marino F. A. Santos; Filipa M. Marques; Rui M. C. Portela; Tânia Perestrelo. Blog "Science is not glamorous". 2018. https://scienceisnotglamorous.com/.
Report
  1. Marino F. A. Santos. 2009. Purificação e preparação de amostras de proteínas e péptidos para estudos estruturais por Ressonância Magnética Nuclear, Cristalografia de Raios-X e Microscopia de Força Atómica.
    10.17699/workshopnpt.13.2
Thesis / Dissertation
  1. Marino F. A. Santos. "Structural and functional studies on the reactivity of CORMs with plasma proteins". PhD, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2016. https://run.unl.pt/handle/10362/19026.
  2. Marino F. A. Santos. "Interacções de proteínas do plasma com potenciais fármacos: estudos 3D a nível molecular". Master, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2011. https://run.unl.pt/handle/10362/6238.
  3. Marino F. A. Santos. "Imprinting Gamético". Degree, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2009.

Artistic / Performance

Artistic exhibition
  1. Permanent Exhibit “Journal Covers” - Department of Chemistry, FCT-UNL. 2015.
  2. Permanent Exhibit “Nobel Prizes in Chemistry” - Department of Chemistry, FCT-UNL. 2015.
  3. Exhibit “Crystallography for Humankind” - 2014 International Year of Crystallography (IYCr2014). 2014.

Other

Dataset
  1. Marino F. A. Santos. PDB entry 4C3W - Vanadium(IV)-Picolinate Complexed with Lysozyme. http://www.rcsb.org/structure/4C3W.
  2. Marino F. A. Santos. PDB entry 4UWV - Lysozyme soaked with a ruthenium based CORM with a pyridine ligand (complex 8). http://www.rcsb.org/structure/4UWV.
  3. Marino F. A. Santos. PDB entry 4UWU - Lysozyme soaked with a ruthenium based CORM with a pyridine ligand (complex 7). http://www.rcsb.org/structure/4UWU.
  4. Marino F. A. Santos. PDB entry 4UWN - Lysozyme soaked with a ruthenium based CORM with a methione oxide ligand (complex 6b). http://www.rcsb.org/structure/4UWN.
  5. Marino F. A. Santos. PDB entry 6SDR - W-formate dehydrogenase from Desulfovibrio vulgaris - Oxidized form. https://www.rcsb.org/structure/6SDR.
  6. Marino F. A. Santos. PDB entry 6SDV - W-formate dehydrogenase from Desulfovibrio vulgaris - Formate reduced form. https://www.rcsb.org/structure/6SDV.
  7. Marino F. A. Santos. PDB entry 7Q0T - Lysozyme soaked with V(IV)OSO4. https://www.rcsb.org/structure/7Q0T.
  8. Marino F. A. Santos. PDB entry 7Q0U - Lysozyme soaked with V(IV)OSO4 and bipy. https://www.rcsb.org/structure/7Q0U.
  9. Marino F. A. Santos. PDB entry 7Q0V - Lysozyme soaked with V(IV)OSO4 and phen. https://www.rcsb.org/structure/7Q0V.
  10. Marino F. A. Santos. PDB entry 7Q0W - Bovine Trypsin co-crystallized with V(IV)OSO4 and phen. https://www.rcsb.org/structure/7Q0W.
  11. Marino F. A. Santos. PDB entry 7Q0X - Bovine Trypsin co-crystallized with V(IV)OSO4 and pic. https://www.rcsb.org/structure/7Q0X.
Other output
  1. Cover Picture "Marcos Históricos em Cristalografia" (Química - Boletim da Sociedade Portuguesa de Química, Número 136 / Volume 39). 2015. Maria João Romão; Teresa Santos-Silva; Isabel Bento; Filipe Freire; Marino F. A. Santos; Ana Luísa Carvalho. https://www.spq.pt/magazines/BSPQuimica/668.
  2. Cover Picture "Vanadium Complexes as Prospective Therapeutics: Structural Characterization of a VIV Lysozyme Adduct" (Eur. J. Inorg. Chem. 21/2014). 2014. Marino F. A. Santos; Ana R. Oliveira; Isabel Correia; Eugenio Garribba; João Costa Pessoa; Teresa Santos-Silva. https://doi.org/10.1002/ejic.201490101.
  3. Critical Recension of the book 'Our Posthuman Future: Consequences of the Biotechnology Revolution' byFrancis Fukuyama. School paper prepared for Bioethics class (Msc Biotechnology). 2010. Marino F. A. Santos.
  4. The (Genetic) Immortality. Scientific Fiction Tale produced within Bioethics class (B.Sc. Cell and Molecular Biology). 2008. Marino F. A. Santos; Rui M. C. Portela; Tânia Perestrelo; Tânia Lucas.
  5. BioJornalética - Bioethics Newspaper within Bioethics class (BSc Cell and Molecular Biology). Co-author and co-editor of BioJornalética - Bioethics Newspaper within Bioethics class (BSc Cell and Molecular Biology). 2007. Marino F. A. Santos.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/11/03 On the biological activities of phenanthroline-containing vanadium complexes 12th International Vanadium Symposium
(Nicosia, Cyprus)
2021/09/30 Enhanced Stability of Detergent-Free Human Native STEAP1 Protein from Neoplastic Prostate Cancer Cells Upon an Innovative Isolation Procedure XVI Annual CICS-UBI Symposium
CICS, FCS-UBI (Covilhã, Portugal)
2020/01 Greenhouse gas (CO2) fixation by the formate dehydrogenase (Fdh) enzyme BioSeminars@UCIBIO
Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (Caparica, Portugal)
2019/07 W/Sec-FdhAB from Desulfovibrio vulgaris Hildenborough: catalytic characterization and crystal structures in oxidized and reduced states Satellite Meeting “FeS for Life” - MoTEC2019 (XI Molybdenum & Tungsten Enzyme)
University of Potsdam, Germany (Potsdam, Germany)
2019/06 The crystal structure of an oxygen-tolerant and highly efficient W-formate dehydrogenase First National Crystallographic Meeting
CCCI (Complexo das Ciências de Comunicação e Imagem), University of Aveiro (Aveiro, Portugal)
2019/06 Structural and biophysical hints to decipher protein-ligand interactions of vanadium compounds 8th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Faculdade de Ciências, Universidade do Porto (Porto, Portugal)
2019/06 Structural and Functional Characterization of a New Bacterial Target Against Tuberculosis: The Phosphatase PtpA 8th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Faculdade de Ciências, Universidade do Porto (Porto, Portugal)
2019/06 LytR from Streptococcus dysgalactiae subs. dysgalactiae: A Target for Biofilm Inhibition 8th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Faculdade de Ciências, Universidade do Porto (Porto, Portugal)
2019/06 The crystal structure of an oxygen-tolerant and highly efficient W-Formate Dehydrogenase 8th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Faculdade de Ciências, Universidade do Porto (Porto, Portugal)
2019/06 Biological activities of phenanthroline-containing vanadium and copper complexes 15th International Symposium on Applied Bioinorganic Chemistry (ISABC15)
Osaka University (Nara, Japan)
2018/09 Relevance of speciatíon in in-vitro experiments with metal-complexes of Cu(II), V(IV/V) or Zn(II) 7th EuCheMS Conference on Nitrogen Ligands
Faculdade de Ciências, Universidade de Lisboa (Lisboa, Portugal)
2018/07 Structural and biophysical characterization of PtpA-inhibitors complexes: a possible target against tuberculosis 1st Meeting of Young Biophysicists
ITQB-UNL (Oeiras, Portugal)
2018/07 Structural and biophysical characterization of protein-vanadium interactions by X-ray crystallography and SAXS 1st Meeting of Young Biophysicists
ITQB-UNL (Oeiras, Portugal)
2017/11/08 Structural Biology for Drug Development Chemforum_CQE
CQE, IST-UL (Lisboa, Portugal)
2017/08 Evaluation and comparison of Cu-, V-, Zn and Fe-complexes containing bipy or phen as ligands as anticancer agents 18th International Conference on Biological Inorganic Chemistry (ICBIC18)
UFSC (Universidade Federal de Santa Catarina) (Florianópolis, Brazil)
2016/06 The active-site pocket of trypsin: a dance hall 5th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
ITQB-UNL (Oeiras, Portugal)
2016/05/05 “Metal Complexes Interacting with Proteins - a Crystallographic insight” C2TN Seminars Cycle
C2TN-UL (Loures, Portugal)
2015/09 Structural Characterization of the Interaction of Ru, Ir and Pt Carbonyls with Lysozyme and Blood Proteins: the Ru-Hb case Joint Meeting of the Working Groups 1 and 5 of the COST Action CM1105 (Functional Metal Complexes that Bind to Biomolecules)
(Belgrade, Serbia)
2015/07 Interaction of vanadium complexes with serum proteins 17th International Conference on Biological Inorganic Chemistry (ICBIC17)
Chinese Chemical Society (CCS) (Beijing, China)
2015/06 Structural Characterization of VIVO(carrier)2-Protein Adducts – New perspectives on Vanadium interactions with Lysozyme, Trypsin and Transferrin 6th European Conference on Chemistry in Life Sciences (6th ECCLS)
Rectorate Universidade Nova de Lisboa (Lisboa, Portugal)
2014/05 New Ruthenium based CORMs, COST Action BM1005 - Gasotransmitters: from basic science to therapeutic applications (ENOG: European Network on Gasotransmitters)
(Messina, Italy)
2014/04 Interaction of therapeutic vanadium complexes with proteins 10th Inorganic Chemistry Conference of the Portuguese Chemical Society
Portuguese Chemical Society (Caparica, Portugal)
2013/12 Interaction of therapeutic vanadium complexes with serum proteins International Symposium on Applied Bioinorganic Chemistry (ISABC12)
(Guangzhou, China)
2013/06 New structural insights on Ru- and Mo- based CORMs interactions with proteins Drug Discovery and Therapy World Congress
(Boston, United States)
2012/11 X-ray crystallography applied to Drug Design at REQUIMTE 43rd Conference Cycle of Chemistry Department
Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (Caparica, Portugal)
2012/06 How CO releasing molecules CO-RMs interact with proteins International Symposia on Metal Complexes (ISMEC 2012)
Fundação Calouste Gulbenkian (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/01 - 2023/07 B.Sc. project in Biochemistry "New strategies against tuberculosis – Exploring putative inhibitors of the phosphatase PtpA"
Co-supervisor of Inês Costa
 Bioquímica (Degree)
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/02 - 2022/07 B.Sc. project in Biochemistry "Finding new inhibitors of the mycobacterium phosphatase PtpA to fight Tuberculosis"
Supervisor of Nuno Ferreira
 Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2018/09 - 2019/11 M.Sc. project in Biochemistry entitled: Structural and functional characterization of a new bacterial target against tuberculosis – The phosphatase PtpA
Co-supervisor of Andreia C. P. Fernandes
 Bioquímica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/09 - 2018/10 M.Sc. project in Bioorganic Chemistry entitled: Structural and functional studies of a new class of Mycobacterium tuberculosis inhibitors
Co-supervisor of Joana Gonçalves
 Química Bioorgânica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01 - 2018/06 B.Sc. project in Biochemistry entitled: Interacção de proteínas e complexos metálicos – Contributo da Cristalografia de raios-X no processo de drug design
Supervisor of Henrique Amado
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/09 - 2015/11 M.Sc. project in Biotechnology entitled: Complexos Organometálicos: caracterização preliminar de compostos de vanádio e de moléculas libertadoras de CO como potenciais fármacos
Co-supervisor of Ana Rita Oliveira
 Biotecnologia (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/01 - 2014/06 B.Sc. project in Biochemistry entitled: Interacção de proteínas com complexos metálicos biologicamente activos
Co-supervisor of Marta Vieira
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/01 - 2013/06 B.Sc. project in Biochemistry entitled: Cristalografia de proteínas aplicada ao drug design
Co-supervisor of Ana Rita Oliveira
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/01 - 2012/06 B.Sc. project in Biochemistry entitled: Interacções de proteínas do plasma com potenciais fármacos
Co-supervisor of Joana Macedo
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2011/04 - Current Co-organizer of the stand "Macromolecular crystallography" at EXPO-FCT - Open Day destined to prospective high school students and to the civil society (2011/04)
Other (Co-organisor)
 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07 - 2018/07 Workshop "X-ray Crystallography" (2018/07 - 2018/07)
Workshop (Other)
 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/07 - 2015/07 Support in the organization of International hands-on Course ISBio2015: Course on Integrative Structural Biology - Integrative Structural Biology tools for the study of protein-ligand interactions (INSTRUCT/COST supported training course) (2015/07 - 2015/07)
Other (Other)
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014/10 - 2014/10 Support in the organization of International hands-on Course ISBio2014: Course on Integrative Structural Biology - Integrative Structural Biology tools for the study of protein-ligand interactions (INSTRUCT/COST supported training course) (2014/10 - 2014/10)
Other (Other)
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2008/10 - 2008/10 The Discovery of the Structure of DNA - Facts and Myths (organized within Science History class) (2009/10 - 2009/10)
Round table (Co-organisor)
 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2020/01 - Current BioSeminars@UCIBIO Conference Cycle
Conference
 BioSeminars@UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2024/01/03 - 2024/01/05 CCP4 Study Weekend 2024: “Decision making in MX – how to be a productive structural biologist”
Conference
 CCP4 Study Weekend 2024: “Decision making in MX – how to be a productive structural biologist”
CCP4 Study Weekend, United Kingdom
2023/11/30 - 2023/11/30 Remote X-ray data collection - Beamline ID23-2, ESRF Synchrotron
Other
 Remote X-ray data collection - Beamline ID23-2, ESRF Synchrotron
ESRF, France
2023/06/18 - 2023/06/18 Remote X-ray data collection - Beamline ID30B, ESRF Synchrotron
Other
 Remote X-ray data collection - Beamline ID30B, ESRF Synchrotron
ESRF, France
2023/04/21 - 2023/04/22 Remote X-ray data collection - Beamline ID23-1, ESRF Synchrotron
Other
 Remote X-ray data collection - Beamline ID23-1, ESRF Synchrotron
ESRF, France
2023/03/24 - 2023/03/24 World Tuberculosis Day Webinar 2023
Seminar
 World Tuberculosis Day Webinar 2023
MDPI AG, Switzerland
2023/02/27 - 2023/02/28 Remote X-ray data collection - Beamline ID30B, ESRF Synchrotron
Other
 Remote X-ray data collection - Beamline ID30B, ESRF Synchrotron
ESRF, France
2023/01/04 - 2023/01/06 CCP4 Study Weekend 2023: Data – Subtle details to big insights
Conference
 CCP4 Study Weekend 2023: Data – Subtle details to big insights
CCP4 Study Weekend, United Kingdom
2022/10/06 - 2022/10/07 Remote X-ray data collection - Beamline ID23-2, ESRF Synchrotron
Other
 Remote X-ray data collection - Beamline ID23-2 ESRF Synchrotron
ESRF, France
2022/09/26 - 2022/09/30 2022 Virtual SSRL/LCLS Users' Meeting
Meeting
 2022 Virtual SSRL/LCLS Users' Meeting
Stanford Synchrotron Radiation Lightsource, United States
2022/04 - 2022/05 Open online course: Introduction to Synchrotron and XFEL Radiation - Techniques and Applications
Workshop
 Open online course: Introduction to Synchrotron and XFEL Radiation - Techniques and Applications
École Polytechnique Fédérale de Lausanne, Switzerland
2022/04/27 - 2022/04/27 "Career Management Skills: why we need them and how to develop them", IRIS, FCT-NOVA
Workshop
 "Career Management Skills: why we need them and how to develop them"
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/03/10 - 2022/03/11 8th Latin American Symposium on Coordination and Organometallic Chemistry - SILQCOM08
Symposium
 8th Latin American Symposium on Coordination and Organometallic Chemistry - SILQCOM08
Universitat Jaume I, Spain
2022/02/28 - 2022/03/01 SLS 2.0 User Workshop/SLS MX User Meeting 2022
Meeting
 SLS 2.0 User Workshop/SLS MX User Meeting 2022
Swiss Light Source - SLS, Switzerland
2022/02/07 - 2022/02/09 ESRF Virtual User Meeting 2022
Meeting
 ESRF Virtual User Meeting 2022
European Synchrotron Radiation Facility (ESRF), France
2022/01/05 - 2022/01/07 CCP4 Virtual Study Weekend 2022: "Current trends in macromolecular model refinement and validation", East Midlands Conference Centre, University of Nottingham, Nottingham, United Kingdom
Conference
 CCP4 Virtual Study Weekend 2022: "Current trends in macromolecular model refinement and validation", East Midlands Conference Centre, University of Nottingham, Nottingham, United Kingdom
University of Nottingham, United Kingdom
2021/11/24 - 2021/11/24 PDB50 in Asia
Symposium
 PDB50 in Asia
Research Collaboratory for Structural Bioinformatics Protein Data Bank, United States
2021/11/01 - 2021/11/03 EMBL Hamburg P12 Virtual User Meeting 2021 EMBL Hamburg P12 Virtual User Meeting 2021
European Molecular Biology Laboratory Hamburg, Germany
2021/10/12 - 2021/10/13 Remote X-ray data collection - Beamline ID30A3, ESRF Synchrotron
Other
 Remote X-ray data collection - Beamline ID30A3, ESRF Synchrotron
ESRF, France
2021/09/20 - 2021/09/24 2021 Virtual Stanford Synchrotron Radiation Lightsource (SSRL) and the Linac Coherent Light Source (LCLS) Users' Meeting
Meeting
 2021 Virtual Stanford Synchrotron Radiation Lightsource (SSRL) and the Linac Coherent Light Source (LCLS) Users' Meeting
Stanford Synchrotron Radiation Lightsource, United States
2021/09/01 - 2021/09/03 S4SAS Conference 2021
Conference
 S4SAS Conference 2021
Diamond Light Source Ltd, United Kingdom
2021/08/31 - 2021/09/01 AlphaFold v2.0 and RoseTTAFold Workshop
Workshop
 AlphaFold v2.0 and RoseTTAFold Workshop
NORA – Norwegian Artificial Intelligence Research Consortium, Norway
2021/06/15 - 2021/06/15 PCISBIO 2021
Seminar
 PCISBIO 2021
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/05/26 - 2021/05/28 7th European Chemical Biology Symposium 2021 (ECBS/LS EuCHEMS)
Symposium
 7th European Chemical Biology Symposium 2021 (ECBS/LS EuCHEMS)
EuChemS, Belgium
2021/05/05 - 2021/05/06 EuroNanoForum 2021
Conference
 EuroNanoForum 2021
International Iberian Nanotechnology Laboratory, Portugal
2021/04/29 - 2021/04/30 SCSB 25th Annual Structural Biology Symposium
Symposium
 SCSB 25th Annual Structural Biology Symposium
The University of Texas Medical Branch at Galveston Sealy Center for Structural Biology and Molecular Biophysics, United States
2021/04/20 - 2021/04/23 CCP-EM Spring Symposium CCP-EM Spring Symposium
CCP-EM, United Kingdom
2021/03/29 - 2021/03/30 Strategy for future EMBL research infrastructures in the Life Sciences in Hamburg
Workshop
 Strategy for future EMBL research infrastructures in the Life Sciences in Hamburg
European Molecular Biology Laboratory Hamburg, Germany
2021/02/16 - 2021/02/16 iNEXT-Discovery 1st Annual Scientific Meeting 2021
Meeting
 iNEXT-Discovery 1st Annual Scientific Meeting 2021
Consejo Superior de Investigaciones Científicas, Spain

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/02/08 - 2021/02/10 ESRF Virtual User Meeting 2021
Meeting
 ESRF Virtual User Meeting 2021
European Synchrotron Radiation Facility (ESRF), France
2021/01/21 - 2021/01/21 SU² 2021 (SOLEIL Users Update 2021)
Meeting
 SU² 2021 (SOLEIL Users Update 2021)
Synchrotron SOLEIL, France
2021/01/05 - 2021/01/08 CCP4 Virtual Study Weekend 2021: "Integrating Structural Biology", East Midlands Conference Centre, University of Nottingham, Nottingham, United Kingdom
Congress
 CCP4 Virtual Study Weekend 2021: "Integrating Structural Biology"
University of Nottingham, United Kingdom
2020/12/17 - 2020/12/17 ALBA Synchrotron - FCT joint (online) Meeting 2020
Meeting
 ALBA Synchrotron - FCT joint (online) Meeting 2020
ALBA Synchrotron, Spain
2020/11/17 - 2020/11/19 EMBL Hamburg P12 Virtual User Meeting
Meeting
 EMBL Hamburg P12 Virtual User Meeting
European Molecular Biology Laboratory Hamburg, Germany
2020/10/14 - 2020/10/16 11th International Workshop on X-ray Radiation Damage to Biological Samples - RD11
Workshop
 11th International Workshop on X-ray Radiation Damage to Biological Samples - RD11
Paul Scherrer Institut, Switzerland
2020/10/09 - 2020/10/10 28th Protein Structure Determination in Industry - Virtual PSDI 2020
Meeting
 28th Protein Structure Determination in Industry - Virtual PSDI 2020
Merck Accounting Solutions and Services Europe GmbH, Germany
2020/09/28 - 2020/10/09 2020 Virtual Stanford Synchrotron Radiation Lightsource (SSRL) and the Linac Coherent Light Source (LCLS) Users' Meeting
Meeting
 2020 Virtual Stanford Synchrotron Radiation Lightsource (SSRL)/Linac Coherent Light Source (LCLS) Users' Meeting
Stanford Synchrotron Radiation Lightsource, United States
2020/10/01 - 2020/10/02 CICS-UBI Symposium 2020
Symposium
 CICS-UBI Symposium 2020
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2020/09/21 - 2020/09/22 S4SAS Conference 2020 - Annual Diamond meeting for users of Small Angle Scattering (SAS).
Conference
 S4SAS Conference 2020
Diamond Light Source Ltd, United Kingdom
2020/09/14 - 2020/09/17 British Biophysical Society 60th Anniversary meeting - Web Edition
Meeting
 British Biophysical Society 60th Anniversary meeting
British Biophysical Society, United Kingdom
2020/09/01 - 2020/09/06 International School of Chemistry - Chemistry for everyday life web edition
Conference
 International School of Chemistry - Chemistry for everyday life
Università degli Studi di Camerino, Italy
2020/05/05 - 2020/06/02 Solution Scattering from Biological Macromolecules - Online Course
Workshop
 Solution Scattering from Biological Macromolecules
European Molecular Biology Laboratory Hamburg, Germany
2020/04/27 - 2020/04/29 MedChemTrain e-School, organized by the MedChemTrain Doctoral Program, covers state of the art research in different areas of medicinal chemistry.
Workshop
 MedChemTrain e-School
2020/01 - 2020/01 Remote X-ray data collection - Beamline XALOC, ALBA Synchrotron
Other
 Remote X-ray data collection - Beamline XALOC, ALBA Synchrotron
ALBA Synchrotron, Spain
2019/12 - 2019/12 Remote X-ray data collection - Beamline I03, Diamond Synchrotron
Other
 Remote X-ray data collection - Beamline I03, Diamond Synchrotron
Diamond Light Source Ltd, United Kingdom
2017/10 - 2019/12 PSST! - LUPA Post-Doc Scientific Short Talks
Conference
 PSST! - LUPA Post-Doc Scientific Short Talks
LUPA - LAQV and UCIBIO Post-Doctoral Association, Portugal
2019/11 - 2019/11 Workshop "Protein purification: Technical tips & tricks"
Workshop
 Protein purification: Technical tips & tricks
GE Healthcare, Spain
2019/07 - 2019/07 Remote X-ray data collection - Beamline I04, Diamond Synchrotron
Other
 Remote X-ray data collection - Beamline I04, Diamond Synchrotron
Diamond Light Source Ltd, United Kingdom
2019/06 - 2019/06 8th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 8th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Universidade do Porto Faculdade de Ciências, Portugal
2019/02 - 2019/02 Remote X-ray data collection - Beamline I04, Diamond Synchrotron
Other
 Remote X-ray data collection - Beamline I03, Diamond Synchrotron
Diamond Light Source Ltd, United Kingdom
2018/10 - 2018/10 Remote X-ray data collection - Beamline I03, Diamond Synchrotron
Other
 Remote X-ray data collection - Beamline I03, Diamond Synchrotron
Diamond Light Source Ltd, United Kingdom
2018/09 - 2018/09 UCIBIO Annual Meeting 2018
Meeting
 UCIBIO Annual Meeting 2018
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2018/07 - 2018/07 Workshop on protein-ligand interactions - Measure Binding Affinities with NanoTemper Technologies
Workshop
 Workshop on protein-ligand interactions - Measure Binding Affinities with NanoTemper Technologies
NanoTemper Technologies GmbH, Germany
2018/07 - 2018/07 1st Meeting of Young Biophysicists, ITQB_UNL, Oeiras, Portugal
Meeting
 1st Meeting of Young Biophysicists
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/06 - 2018/06 7th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 7th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/06 - 2018/06 3rd PCISBIO Day
Meeting
 3rd PCISBIO Day
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/05 - 2018/06 X-ray and SAXS data collection - Beamline P13/P12, Diamond Synchrotron
Other
 X-ray and SAXS data collection - Beamline P13/P12, Diamond Synchrotron
Deutsches Elektronen-Synchrotron, Germany
2018/03 - 2018/06 8th LAQV-UCIBIO Conference Cycle
Conference
 8th LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2017/10 - 2018/06 7th LAQV-UCIBIO Conference Cycle
Conference
 7th LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2018/04 - 2018/04 SAXS data collection - Beamlines BM29, ESRF Synchrotron
Other
 SAXS data collection - Beamlines BM29, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2018/01 - 2018/01 Leadership for a better future
Workshop
 WORKS4U - Workshops for Funding Applications & Career Development
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/12 - 2017/12 X-ray data collection - Beamlines ID30B and ID23.2, ESRF Synchrotron
Other
 X-ray data collection - Beamlines ID30B and ID23.2, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2017/11 - 2017/11 VCW (Value Creation Wheel) – Finding the best job for me
Workshop
 WORKS4U - Workshops for Funding Applications & Career Development
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/05 - 2017/07 6th LAQV-UCIBIO Conference Cycle
Conference
 6th LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2017/05 - 2017/05 ABC of Career Management for Young Researchers
Workshop
 WORKS4U - Workshops for Funding Applications & Career Development
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/05 - 2017/05 6th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 6th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Laboratório Nacional de Energia e Geologia - Campus do Lumiar, Portugal
2017/02 - 2017/04 5th LAQV-UCIBIO Conference Cycle
Conference
 5th LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2017/02 - 2017/02 How to Write a Good CV
Workshop
 WORKS4U - Workshops for Funding Applications & Career Development
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/02 - 2017/02 X-ray data collection - Beamline ID29, ESRF Synchrotron
Other
 X-ray data collection - Beamline ID29, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2017/01 - 2017/01 Insights into FCT Project Applications WORKS4U - Workshops for Funding Applications & Career Development
2017/01 - 2017/01 CCP4 Study Weekend 2017: Crystal to Structure, East Midlands Conference Centre, University of Nottingham, Nottingham, United Kingdom
Meeting
 CCP4 Study Weekend 2017: Crystal to Structure
University of Nottingham, United Kingdom
2016/10 - 2016/12 4th LAQV-UCIBIO Conference Cycle
Conference
 4th LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2016/09 - 2016/09 Tips & Tricks for Successful Funding WORKS4U - Workshops for Funding Applications & Career Development
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2016/09 - 2016/09 X-ray data collection - Beamline ID30A.3, ESRF Synchrotron
Other
 X-ray data collection - Beamline ID30A.3, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2016/03 - 2016/07 3rd LAQV-UCIBIO Conference Cycle
Conference
 3rd LAQV-UCIBIO Conference Cycle
2016/05 - 2016/05 5th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 5th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/01 - 2016/03 2nd LAQV-UCIBIO Conference Cycle
Conference
 2nd LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2015/12 - 2015/12 Workshop "Thermal Shift Assay (TSA)"
Workshop
 Workshop "Thermal Shift Assay (TSA)"
Thermo Fisher Scientific, Spain
2015/09 - 2015/12 1st LAQV-UCIBIO Conference Cycle
Conference
 1st LAQV-UCIBIO Conference Cycle
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2015/07 - 2015/07 2nd ISBio (ISBio2015), FCT/UNL, Caparica, Portugal
Other
 ISBio2015: Integrative Structural Biology tools for the study of protein-ligand interactions
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/06 - 2015/06 In-house X-ray data collection - D8 Venture Bruker (Postgraduate Certificate)
Workshop
 In-house X-ray data collection - D8 Venture Bruker (Postgraduate Certificate)
Bruker AXS GmbH, Germany
2015/06 - 2015/06 X-ray data collection - Beamline ID23.1, ESRF Synchrotron
Other
 X-ray data collection - Beamline ID23.1, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2014/04 - 2015/06 45th Conference Cycle - Chemistry Department (International Crystallography Year)
Conference
 45th Conference Cycle - Chemistry Department (International Crystallography Year)
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/04 - 2015/04 4th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 4th Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/02 - 2015/02 X-ray data collection - Beamline PXIII, SLS Synchrotron
Other
 X-ray data collection - Beamline PXIII, SLS Synchrotron
Swiss Light Source - SLS, Switzerland
2015/02 - 2015/02 SAXS data collection - Beamline BM29, ESRF Synchrotron
Other
 SAXS data collection - Beamline BM29, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2014/11 - 2014/11 X-ray data collection - Beamline Proxima1, Soleil Synchrotron
Meeting
 X-ray data collection - Beamline Proxima1, Soleil Synchrotron
Synchrotron SOLEIL, France
2014/10 - 2014/10 X-ray data collection - Beamline ID23.1, ESRF Synchrotron
Other
 X-ray data collection - Beamline ID23.1, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2014/10 - 2014/10 BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the European Synchrotron Radiation Facility
Seminar
 BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the European Synchrotron Radiation Facility
European Synchrotron Radiation Facility (ESRF), France
2014/07 - 2014/07 1st PCISBIO Day
Meeting
 1st PCISBIO Day
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014/06 - 2014/06 SAXS data collection - Beamline BM29, ESRF Synchrotron
Other
 SAXS data collection - Beamline BM29, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2014/05 - 2014/06 47th Crystallographic Course: Structural Basis of Pharmacology, Erice, Italy
Other
 47th Crystallographic Course: Structural Basis of Pharmacology
Ettore Majorana Centre, Italy
2014/04 - 2014/04 3rd Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 3rd Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
2014/04 - 2014/04 ENEBIOQ VII, FCT/UNL, Caparica, Portugal
Meeting
 ENEBIOQ VII - Encontro Nacional de Estudantes de Bioquímica
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/03 - 2014/03 X-ray data collection - Beamline Proxima1, Soleil Synchrotron
Other
 X-ray data collection - Beamline Proxima1, Soleil Synchrotron
Synchrotron SOLEIL, France
2014/02 - 2014/03 44th Conference Cycle - Chemistry Department
Conference
 44th Conference Cycle - Chemistry Department
REQUIMTE, Portugal
2014/01 - 2014/01 CCP4 Study Weekend 2014: Two Way Street - Complementary Methods, East Midlands Conference Centre, University of Nottingham, Nottingham, United Kingdom
Meeting
 CCP4 Study Weekend 2014: Two Way Street - Complementary Methods,
University of Nottingham, United Kingdom
2013/12 - 2013/12 X-ray data collection - Beamline PXIII, SLS Synchrotron
Other
 X-ray data collection - Beamline PXIII, SLS Synchrotron
Swiss Light Source - SLS, Switzerland
2013/10 - 2013/10 X-ray data collection - Beamline I03, Diamond Synchrotron
Other
 X-ray data collection - Beamline I03, Diamond Synchrotron
Diamond Light Source Ltd, United Kingdom
2013/07 - 2013/07 9th European Biophysics Congress (EBSA2013), Pavilhão Atlântico, Lisboa, Portugal
Congress
 9th European Biophysics Congress (EBSA2013)
Pavilhão Atlântico, Portugal
2012/10 - 2013/06 43rd Conference Cycle - Chemistry Department
Conference
 43rd Conference Cycle - Chemistry Department
REQUIMTE, Portugal
2013/02 - 2013/02 2nd Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 2nd Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Pavilhão do Conhecimento, Portugal
2012/11 - 2012/11 X-ray data collection - Beamline BM30, ESRF Synchrotron
Other
 X-ray data collection - Beamline BM30, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2012/10 - 2012/10 SAXS data collection - Beamline BM29, ESRF Synchrotron
Other
 SAXS data collection - Beamline BM29, ESRF Synchrotron
European Synchrotron Radiation Facility (ESRF), France
2012/09 - 2012/09 "BioCrys2012 - Fundamental of Modern Methods of BioCrystallography", ITQB/UNL, Oeiras, Portugal
Other
 BioCrys2012 - Fundamental of Modern Methods of BioCrystallography
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012/07 - 2012/07 V Hands-on Course "From Proteomics to Proteins", FCT/UNL, Caparica, Portugal
Other
 V Hands-on Course "From Proteomics to Proteins",
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/01 - 2012/07 42nd Conference Cycle - Chemistry Department
Conference
 42nd Conference Cycle - Chemistry Department
REQUIMTE, Portugal
2012/01 - 2012/01 1st Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Meeting
 1st Meeting of the Synchrotron Radiation Users from Portugal (ENURS)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/01 - 2009/06 Exposition "A Revolução Darwiniana"
Exhibition
 Exposition "A Revolução Darwiniana"
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/07 Finding new inhibitors of the mycobacterium phosphatase PtpA to fight Tuberculosis
Supervisor
 Nuno Ferreira (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/07 Structural studies on a type VI sulfide:quinone oxidoreductase (Sqr) from the bacterium Thiocapsa roseopersicina
(Thesis) Arguer
 Sofia Costa (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07 Interacção de proteínas e complexos metálicos – Contributo da Cristalografia de raios-X no processo de drug design
Supervisor
 Henrique Amado (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07 Enzymatic arsenite oxidation at the molecular level: X-ray Crystallography and Small Angle X-ray Scattering
(Thesis) Arguer
 Filipa Lopes (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Association member

Society Organization name Role
2017/06 - Current LUPA - LAQV and UCIBIO Post-Doctoral Association

Committee member

Activity description
Role 		Institution / Organization
2012/01 - Current Operating Oryx8 Nanocrystallization Robot (Douglas Instruments) team - Macromolecular crystallography (XTAL) Group
Member
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2012/01 - Current Lab management (consumables and hard drives) team - Macromolecular crystallography (XTAL) Group
Member
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2012/10 - 2016/12 Evacuation Team of the Internal Emergency Plan of the TOMO 3 - Edifício Departamental (Chemistry wing, 6th Floor)
Member
 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Consulting

Activity description Institution / Organization
2012 - Current Reviewing different BSc, MSc and PhD scientific works (papers, oral and poster presentations, reports, theses)
2023/11 - 2023/12 Consultant of the scientific program of the Advanced Course "Medical Structural Biology" requested by Professor Luís Passarinha Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2012/03 - Current Fundaments of Structural Biochemistry (support in practical class "Crystallization and data collection") Bioquímica (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/03 - Current Structural Biochemistry (support in practical class "Crystallization and data collection") Bioquímica (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07 - 2018/07 Practical lesson - Bioquímica – Protein crystallization: crystal manipulation, soaking and mounting and cryo-conservation; Theoretical lesson - Structural Analysis: protein-ligand/drug interactions Workshop "X-ray Crystallography" (Outros) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014/05 - 2014/05 Structural Bioorganic Chemistry (Practical lesson "CSD - Cambridge Structural Database" Química Bioorgânica (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/04 - 2014/04 Structural Biochemistry (practical class "PDB database and Chimera software") Bioquímica (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/10 - 2013/10 Methods for Characterization of Biomolecules (Theoretic-pratical lesson - X-ray Crystallography applied to Drug Design) Bioquímica para a Saúde (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/03 - 2012/03 Biochemistry I (Practical class) Bioquímica (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2021/02/01 Disclosing the enzymatic reaction mechanism for the reduction of carbon dioxide. ESRF highlights 2020 Booklet
2020/03/06 Portuguese article about the Fdh protein "Portugueses identificam funcionamento de bactéria que absorve CO2 e produz combustível" Expresso
2018/11 The treatment of rheumatoid arthritis generally consists of anti-inflammatory drugs, but we explain why we hope carbon monoxide will become the treatment of the future. Impact.pub

Interview (tv / radio show)

Program Topic
2020/09/28 - 2020/09/28 “90 segundos de ciência” Laboratório estuda Proteína capaz de converter Dióxido de carbono em Combustível
2018/04/18 - 2018/04/18 “90 segundos de ciência” - ANTENA 1 De gás tóxico para agente anti-inflamatório. Investigadora estuda aplicação de monóxido de carbono no tratamento da artrite reumatóide

Journal scientific committee

Journal title (ISSN) Publisher
2023/09 - Current Computational and Structural Biotechnology Journal Elsevier
2023/04 - Current Life (2075-1729) MDPI
2022/06 - Current International Journal of Molecular Sciences (1422-0067) MDPI
2022/02 - Current Molecules (1420-3049) MDPI
2022/01 - Current Inorganics (2304-6740) MDPI

Mentoring / Tutoring

Topic Student name
2022/09 - Current M.Sc. in Biotechnology - Tutor Nuno Ferreira
2020/05 - Current Structural (X-ray Crystallography) and biophysical protein characterization Filipa Engrola
2020/01 - Current Structural (X-ray Crystallography) and biophysical protein characterization João Paquete Ferreira
2019/06 - Current TSA assays applied to the protein sCOMT Margarida Gonçalves
2019/07 - 2022/07 B.Sc. in Cell and Molecular Biology - Tutor Carolina Pereira
2019/07 - 2021/02/19 M.Sc. project in Biochemistry entitled: Structure and Function of Target Proteins for the Design of New Inhibitors Raquel Gama
2019/11 - 2020/09 Structural and biophysical studies applied to Drug Design Andreia C. P. Fernandes
2019/09 - 2020/03 TSA assays applied to the protein sCOMT Pedro Vicente
2019/01 - 2020/03 M.Sc project in Bioorganic Chemistry entitled: BSA@CORM-3 effect in AIA rats and spectroscopic studies Inês Mendonça Martins
2018/09 - 2019/11 M.Sc. project in Biochemistry entitled: Bacterial arsenite oxidation at the molecular level Filipa Engrola
2018/07 - 2019/10 M.Sc. project in Biochemistry entitled: LytR Inhibition, an Approach to Avoid Biofilm Formation in Streptococcus dysgalactiae subs. dysgalactiae João Paquete Ferreira
2013/12 - 2019/09 Strcutural and biophysical of protein-ligand interactions Jayamaran Muthukumaran
2017/09 - 2018/11 M.Sc. project in Bioorganic Chemistry entitled: Caracterização estrutural e funcional da MsmK, uma ATPase multitarefa de Streptoccocus pneumoniae Bruno Carneiro
2016/09 - 2018/11 M.Sc. project in Biochemistry entitled: Structure based drug design for the discovery of promising inhibitors of human Bcl-2 and Streptococcus dysgalactiae LytR proteins João Ramos
2018/06 - 2018/06 Curricular Internship (Lab Analysis Technician) from Profissional School EPED (Almada) Camila Oliveira
2017/04 - 2017/09 Improvement of crystallization using photocromic agents Mário Soromenho
2017/01 - 2017/07 Project CORMs and gold nanoparticles Rita Mendes
2015/07 - 2016/11 M.Sc. project in Biochemistry entitled: Arsenito oxidase bacteriana: caracterização a nível molecular Marta Vieira
2015/12 - 2016/01 Project CORMs and gold nanoparticles Joana Marques
2015/11 - 2015/11 M.Sc. Biochemistry (Lab Rotation of Biomolecular Techniques I Curricular Unit 2015) - Crystallization and X-ray crystallography of proteins Frederico Lourenço
2014/09 - 2015/11 M.Sc. project in Biochemistry entitled: Estudo da interação proteína-ligando em proteases de serina para desenvolvimento de inibidores da Uroquinase Cátia Silva
2015/01 - 2015/06 B.Sc. project in Biochemistry entitled: Estudos cristalográficos sobre a interacção de líquidos iónicos e nanopartículas com macromoléculas biológicas Gonçalo Nunes
2013/09 - 2014/12 Structural characterization of protein-ligand interactions Francisco Leisico
2013/09 - 2014/11 M.Sc. project in Biochemistry: Structural and functional characterization of ModA and TupA proteins belonging to the molybdate and tungstate transport system from desulfovibrio alaskensis G20 Raquel Cordeiro
2014/08 - 2014/08 Solving a X-ray protein structure Diana Vieira
2010/07 - 2013/07 B.Sc. in Cell and Molecular Biology - Tutor Rute Pinto
2012/12 - 2012/12 M.Sc. in Biochemistry ( Lab Rotation of Biomolecular Techniques I Curricular Unit 2012): Cristalografia de raios-X Frederico Marques
2012/12 - 2012/12 M.Sc. in Biochemistry ( Lab Rotation of Biomolecular Techniques I Curricular Unit 2012): Cristalografia de raios-X Nuno Santos
2012/07 - 2012/09 Interaction of V-based complexes with human serum transferrin Sameena Mehtab
2007/09 - 2011/07 B.Sc. in Cell and Molecular Biology - Tutor Duarte Martins
2011/01 - 2011/06 B.Sc. project in Biochemistry entitled: Cristalização de complexos formados entre proteína L artificial e anticorpos Susana Barão
2011/01 - 2011/06 B.Sc. project in Biochemistry entitled: Cristalização de complexos formados entre proteína A artificial e anticorpos Cristiana Pinheiro
2007/09 - 2010/06 B.Sc. in Cell and Molecular Biology - Tutor Sílvia Lourenço
Distinctions

Award

2018 Best poster award (Joana J. F. Gonçalves, Francisco Leisico, Marino F. A. Santos, Hernán Terenzi, Teresa Santos-Silva, "Structural and functional studies of a new class of Mycobacterium tuberculosis inhibitors")
7th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), FCT-NOVA, Caparica, Portugal, Portugal
2009 Best poster award (Marino F. A. Santos, Rui M. C. Portela, Tânia Leandro, Tânia Perestrelo, "Notebooks de Darwin")
Exposição "A rEvolução Darwiniana", FCT-NOVA, Caparica, Portugal , Portugal

Other distinction

2023 Feature paper: "Interaction of Vanadium Complexes with Proteins: Revisiting the Reported Structures in the Protein Data Bank (PDB) since 2015"
MDPI AG, Switzerland
2020 Selection to the final poster presentation contest with the poster "A Structure-based Drug Design Approach to Fight Tuberculosis - Developing New Inhibitors Targeting the Phosphatase PtpA"
11th AIMS Meeting, Portugal
2019 Selection to the final poster presentation contest with the poster "Structural and Functional Characterization of a New Bacterial Target Against Tuberculosis: The Phosphatase PtpA"
iMed Conference 11.0, Lisboa, Portugal, Portugal
2017 Post-Doctoral Scholarship BPD/CQE-2017-029
Universidade de Lisboa Centro de Química Estrutural, Portugal
2017 Travel Bursary for CCP4 Study Weekend 2017 (University of Nottingham)
CCP4 Study Weekend, United Kingdom
2016 Post-Doctoral Scholarship under the project PTDC/QEQ-MED/1902/2014
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014 Travel Bursary for CCP4 Study Weekend 2014 (University of Nottingham)
CCP4 Study Weekend, United Kingdom
2014 Travel Bursary for the 47th Crystallographic Course: Structural Basis of Pharmacology, Erice, Italy
Ettore Majorana Centre, Italy
2012 PhD Scholarship SFRH/BD/77894/2011 ("Structural and Functional studies on the Reactivity of CORMs with plasma proteins")
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2008 Integration into Research Scholarship (Bolsa de Integração na Investigação, BII) - Attributed to the best undergraduate students
Fundação para a Ciência e a Tecnologia, I.P., Portugal