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Renato B. Pereira awarded his PhD degree in Pharmaceutical Sciences - Phytochemistry and Pharmacognosy Speciality (2019) from the University of Porto, Faculty of Pharmacy (UPFP). His research interests focus natural products chemistry and the assessment of their biological properties, with special emphasis in anti-inflammatory and anticancer activities. His research career has resulted in 40+ peer-reviewed papers, 12 as first author and 3 as corresponding author, 1 book chapter, 1 international patent, and participation in 7 funded national and 2 international projects, 1 as Co-PI, 1 as research team member and 7 as research fellow.
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Identification

Personal identification

Full name
Renato Joel Barros Pereira
Date of birth
1989/10/06

Citation names

  • Pereira, Renato B.
  • Pereira, RB

Author identifiers

Ciência ID
E813-03FA-043D
ORCID iD
0000-0001-8500-7364
Scopus Author Id
55802371953

Email addresses

  • rjpereira@ff.up.pt (Professional)

Telephones

Telephone
  • 220428654 (Professional)

Addresses

  • Requimte/Faculdade de Farmácia, Universidade do Porto. Rua de Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
  • Natural sciences - Biological Sciences - Marine Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Italian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Portuguese (Mother tongue)
Education
Degree Classification
2015/09/01 - 2019/12/06
Concluded
 PhD in Pharmaceutical Sciences (Doutoramento)
Major in Phytochemistry and Pharmacognosy
Universidade do Porto Faculdade de Farmácia, Portugal
"Bioprospecting Aplysia sea hares as valuable sources of bioactive molecules" (THESIS/DISSERTATION)
 Approved
2012/11/06
Concluded
 Integrated Master's in Pharmaceutical Sciences (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
"Vitamin D and the metabolic syndrome" (THESIS/DISSERTATION)
 15/20
Affiliation

Science

Category
Host institution 		Employer
2023/05/01 - Current Contracted Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2022/06/01 - 2023/04/30 Research Assistant (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
(...)
2021/05/01 - 2022/01/31 Contracted Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2020/05/11 - 2021/03/10 Postdoc (Research) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2021/09/06 - 2022/02/19 Invited Assistant (University Teacher) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
2020/01/22 - 2020/04/21 Research fellowship in project "MILKQUA" (PRIMA/0007/2018 -BI1) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2019/10/01 - 2019/12/31 BI scholarship in project "IBERPHENOL - Red cooperativa de investigación en el ámbito de polifenoles y sus aplicaciones industriales" (0377_IBERPHENOL_6_E) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09/01 - 2019/08/31 FCT-funded PhD scholarship (PD/BD/113565/2015) under the program in Medicines and Pharmaceutical Innovation (i3DU) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2013/11/01 - 2015/07/31 BI scholarship in project "ALGADOURADA" (31-03-05-FEP-041) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
(...)
2012/11/01 - 2013/09/30 BI scholarship in project "Protection against pests of the olive tree: promoting the action of natural enemies for the establishment of native flora" (PTDC/AGR-AAM/102908/2008) Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2012/06/01 - 2012/08/31 Internship in community pharmacy at "Farmácia Ferreira da Silva", Matosinhos (Portugal) Universidade do Porto Faculdade de Farmácia, Portugal
2012/03/01 - 2012/05/31 Research internship in the Department of Pharmacy of the Universitá Degli studi G. D'annunzio, Chieti-Pescara (Italy) Università degli Studi Gabriele d'Annunzio Chieti Pescara Dipartimento di Farmacia, Italy
Università degli Studi Gabriele d'Annunzio Chieti Pescara Dipartimento di Farmacia, Italy
Projects

Grant

Designation Funders
2020/05/11 - 2021/03/10 "MILKQUA" (PRIMA/0007/2018 -BIPD1)
PRIMA/0007/2018 -BIPD1
Post-doc Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/10/01 - 2019/12/31 "IBERPHENOL - Red cooperativa de investigación en el ámbito de polifenoles y sus aplicaciones industriales" (0377_IBERPHENOL_6_E)
0377_IBERPHENOL_6_E
Research Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2015/09/01 - 2019/08/31 Bioprospecting Aplysia sea hares as valuable sources of bioactive molecules
PD/BD/113565/2015
PhD Student Fellow
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/11/01 - 2015/07/31 ALGA DOURADA - Selection and evaluation of of seaweed species as an additive for seabream (Dicentrarchus labrax) diets. (31-03-05-FEP-041)
31-03-05-FEP-041
Research Fellow
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Concluded
2012/11/01 - 2013/09/30 Sustainable control of olive pests: enhancement of natural enemies' activity through the establishment of native floral vegetation (PTDC/AGR-AAM/102908/2008)
PTDC/AGR-AAM/102908/2008
Research Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2023/05/01 - Current KIWIBOL - Looking Beyond KIWIfruit ESCA Complex to Define a PeptaiBOL-based Strategy to Disease Control
PTDC/ASP-PLA/2440/2021
Researcher
REQUIMTE LAQV Porto, Portugal
Ongoing
2021/01/01 - 2023/12/31 Marine Chemiluminescence as a Broad-Spectrum Anticancer Therapy with Enhanced Tumor-Selectivity and Activity
PTDC/QUI-QFI/2870/2020
Research team member
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/06/01 - 2023/04/30 MARemPÓ: Sustainable source of compounds for the development of commercial products for aquaculture
POCI-01-0247-FEDER-047200
Researcher
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Ongoing
2022/02/17 - 2023/03/31 Milk quality all along the dairy chain for a sustainable MILK
PRIMA/0007/2018
Co-Principal Investigator (Co-PI)
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2021 - Current Characterization of the structural changes of bio-macromolecules upon cells interaction with tumor-selective and self-activating photosensitizers based on Coelenterazine: FTIR spectroscopical study
2021075222
Research team member
Universidade do Porto Faculdade de Farmácia, Portugal

REQUIMTE LAQV Porto, Portugal
ALBA Synchrotron
Ongoing
Outputs

Publications

Book chapter
  1. Pereira, RB; Dasari, R; Lefranc, F; Kornienko, A; Kiss, R; Gomes, NGM. "Targeting Enzymatic Pathways with Marine-Derived Clinical Agents". In Natural Products Targeting Clinically Relevant Enzymes, 255-275. Wiley-VCH Verlag GmbH & Co. KGaA, 2017.
    10.1002/9783527805921.ch10
Conference abstract
  1. Pereira, RB; Oliveira, AP; Valentão, P; Andrade, PB. "Fatty Acids from Edible Sea Hares: Anti-Inflammatory Capacity in LPS-Stimulated RAW 264.7 Cells Involves iNOS Modulation". Paper presented in 11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry, 2016.
    10.1039/c4ra14333g
Conference paper
  1. José Ricardo A. Coelho; Tatiana F. Vieira; Renato B. Pereira; David M. Pereira; Elisabete M. S. Castanheira; António Gil Fortes; Sérgio F. Sousa; Maria José G. Fernandes; Maria Sameiro T. Gonçalves. "Synthesis, Insecticidal Activity and Computational Studies of Eugenol-Based Insecticides". 2022.
    10.3390/ecsoc-26-13649
  2. Ribeiro, MAF; Vieira, TF; Fernandes, MJG; Pereira, RB; Pereira, DM; Castanheira, EMS; Fortes, AG; Sousa, SF; Gonçalves, MST. "Synthesis and in silico evaluation of potential insecticide activity of benzamides". Paper presented in 25th International Electronic Conference on Synthetic Organic Chemistry, 2021.
    Published
  3. Teixeira, C; Pinto, NFS; Pereira, DM; Pereira, RB; Fernandes, MJG; Castanheira, EMS; Fortes, AG; Gonçalves, MST. "Cytotoxicity studies of eugenol amino alcohols derivatives". Paper presented in 25th International Electronic Conference on Synthetic Organic Chemistry, 2021.
    Published • https://doi.org/10.3390/ecsoc-25-11689 (registering DOI)
  4. José R. A. Coelho; Tatiana F. Vieira; Renato B. Pereira; David M. Pereira; Elisabete M. S. Castanheira; A. Gil Fortes; Sérgio F. Sousa; Maria José G. Fernandes; M. Sameiro T. Gonçalves. "Eugenol Ester Derivatives: Synthesis, Insecticidal Activity and Computational Studies". 2021.
  5. Coelho, CMM; Fernandes, MJG; Pereira, DM; Pereira, RB; Fortes, AG; Gonçalves, MST; Castanheira, EMS. "Synthesis, insecticidal activity and nanoencapsulation studies of alkoxy alcohols from eugenol". Paper presented in 25th International Electronic Conference on Synthetic Organic Chemistry, 2021.
    https://doi.org/10.3390/ecsoc-25-11788 (registering DOI)
  6. Coelho, JRA; Vieira, TF; Pereira, RB; Pereira, DM; Castanheira, EMS; Fortes, AG; Sousa, SF; Fernandes, MJG; Gonçalves, MST. "Eugenol ester derivatives: synthesis, insecticidal activity and computational studies". Paper presented in 25th International Electronic Conference on Synthetic Organic Chemistry, 2021.
    https://doi.org/10.3390/ecsoc-25-11787 (registering DOI)
  7. Natal, CM; Pereira, DM; Pereira, RB; Fernandes, MJG; Fortes, AG; Castanheira, EMS; Gonçalves, MST. "Carvacrol Derivatives with Potential Insecticidal Activity". Paper presented in 24th International Electronic Conference on Synthetic Organic Chemistry, 2020.
    Published • 10.3390/ecsoc-24-08334
  8. Fernandes, MJG; Pereira, DM; Pereira, RB; Fortes, AG; Castanheira, EMS; Gonçalves, MST. "Synthesis and Insecticidal Activity of O-alkylated Oxirane Eugenol Derivatives". Paper presented in 24th International Electronic Conference on Synthetic Organic Chemistry, 2020.
    Published • 10.3390/ecsoc-24-08335
  9. Pinto, NFS; Pereira, DM; Pereira, RB; Fortes, AG; Fernandes, MJG; Castanheira, EMS; Gonçalves, MST. "Synthesis of Amino Alcohols from Eugenol and Their Insecticidal Activity against Sf9 Cell Line". Paper presented in 24th International Electronic Conference on Synthetic Organic Chemistry, 2020.
    Published • 10.3390/ecsoc-24-08337
Conference poster
  1. Pereira, RB; Gomes, A; Ferreira, M; Gameiro, P; Gomes, P. "Synthesis and antibacterial activity of Trichoderma longibrachiatum longibramide E analogs". Paper presented in Iberian Peptide Meeting, 2023.
  2. Coelho, José R. A.; Pereira, Renato B.; Pereira, David M.; Castanheira, Elisabete M. S.; Fortes, A. G.; Fernandes, Maria José G.; Gonçalves, M. Sameiro T.. "New potential insecticide candidates based on eugenyl 3-aminobenzoates". Paper presented in 8th PYCHEM – Portuguese Young Chemistry Meeting, 2023.
  3. Ceciliani, F; Nehme, R; Cremonesi, P; Castiglioni, B; Biscarini, F; Ciccola, M; Di Mauro, S; et al. "The effects of external treatment with essential oils on milk quality: a lipidomics approach". Paper presented in 73rd Annual Meeting of the European Federation of Animal Science, 2022.
  4. Pinto, NFS; Teixeira, C; Pereira, DM; Pereira, RB; Fernandes, MJG; Castanheira, EMS; Fortes, AG; Gonçalves, MST. "Synthesis of amino alcohols from eugenol and their biological evaluation against AGS cell line". Paper presented in Chemistry and Opportunities in a Global Society - XXVII National Meeting of the Portuguese Chemical Society, 2021.
  5. Coelho, JRA; Fernandes, MJG; Pereira, RB; Pereira, DM; Castanheira, EMS; Fortes, AG; Gonçalves, MST. "Eugenol derivatives with potential insecticide activity". Paper presented in Chemistry and Opportunities in a Global Society - XXVII National Meeting of the Portuguese Chemical Society, 2021.
  6. Duarte, JMSGP; Fernandes, MJG; Pereira, DM; Pereira, RB; Fortes, AG; Rodrigues, ARO; Castanheira, EMS; Gonçalves, MST. "Synthesis, insecticidal activity and encapsulation of carvacrol and thymol derivatives". Paper presented in Chemistry and Opportunities in a Global Society - XXVII National Meeting of the Portuguese Chemical Society, 2021.
  7. Pereira, RB; Almeida, AA; Pereira, DM; Silva, OMD; Andrade, PB; Pinto, E; Valentão, P. "Trace elements in wild edible Aplysia species: relationship with the desaturation-elongation indexes of fatty acids". Paper presented in 10th Postgraduate iMed.ULisboa Students Meeting & 3rd i3DU Meeting, 2018.
  8. Moreira, AS; Fernandes, F; Carvalho, ÁMM; Pereira, RB; Jesus, RS; Pereira, DM; Valentão, P; et al. "Fatty acid profiling of Armina maculata and assessment of its potential as a producer of anti-inflammatory agents". Paper presented in 11th Meeting of Young Researchers of University of Porto, 2018.
  9. Vieira, MD; Carvalho, Á; Figueiredo-González, M; Pereira, RB; Pereira, DM; Valentão, P; Andrade, PB; Gomes, NGM. "Valorization of the invasive red macroalgae Grateloupia turuturu as a potential source of anti-inflammatory agents". Paper presented in 10th Meeting of Young Researchers of University of Porto, 2017.
  10. Pereira, RB; Gomes, NGM; Andrade, PB; Valentão, P. "Refreshing the marine-derived chemotherapeutic pipeline". Paper presented in 8th Postgraduate iMed.ULisboa Students Meeting & 1st i3DU Meeting, 2016.
  11. Valentão, Patrícia; Bernardo, João; Andrade, Catarina; Pereira, Renato B.; Andrade, Paula B.; Grosso, Clara. "Comparation between two methodologies to evaluate monoaminoxidase-A inhibition by polyphenol-rich extracts". Paper presented in XXVIII International Conference in Polyphenols, 2016.
  12. Pereira, RB; Andrade, PB; Valentão, P. "Aplysia sea hares from Portuguese coast: fatty acids composition and their anti-inflammatory properties". Paper presented in GEOMAR-Biotech Mini Symposium - Challenges and Opportunities in Marine Biotechnology Research and Development in Europe, 2015.
  13. Pereira, RB; Schindler, B; Silva, LR. "In vitro studies to assess the biological potential of Endopleura uchi". Paper presented in 7th Meeting of Young Researchers of University of Porto, 2014.
  14. Pereira, RB; Pinto, DCGA; Pereira, DM; Gomes, NGM; Silva, OMD; Silva, AMS; Andrade, PB; Valentão, P. "UHPLC-MS/MS profiling of Aplysia depilans and assessment of its potential therapeutic use". Paper presented in 9th Postgraduate iMed.ULisboa Students Meeting & 2nd i3DU Meeting, 2013.
  15. Valentão, P; Pereira, RB; Grosso, C; Azevedo, C; Andrade, PB. "Phenolic compounds from Jacaranda caroba: interfaces with neurodegenerative disorders". Paper presented in XXIII National Meeting of the Portuguese Society of Chemistry, 2013.
  16. Costa, A; Pereira, RB; Valentão, P; Andrade, PB; Sousa, C. "Binary mixtures with phenolic compounds and BHT: synergistic or antagonistic antioxidant effects". Paper presented in 6th Meeting of Young Researchers of University of Porto, 2013.
  17. Pereira, RB; Costa, A; Valentão, P; Andrade, PB; Sousa, C. "Glutathione and the antioxidant potential of binary mixtures with phenolic compounds". Paper presented in 6th Meeting of Young Researchers of University of Porto, 2013.
  18. Pereira, RB; Silva, G.; Valentão, P; Andrade, PB; Sousa, C. "Antioxidant potential of binary mixtures of phenolic compounds: synergistic or antagonistic effects". Paper presented in 5th Meeting of Young Researchers of University of Porto, 2012.
  19. Oliveira, AP; Martins, FM; Tavares, H; Cêrca, J; Osório, MV; Pereira, RB; Morgado, S; Mota, V. "Spiny sea-star (Marthasterias glacialis Linnaeus) - beyond what we see". Paper presented in 5th Meeting of Young Researchers of University of Porto, 2012.
Journal article
  1. Filho, JLP; Pereira, RB; Vieira, TF; Sousa, SF; Gonçalves, MST; Pereira, DM. Corresponding author: Pereira, RB. "Development of eugenol derivatives with 5-LOX inhibitory activity". (2024):
    Submitted
  2. Magalhães, CM; Pereira, RB; Erbiai, El Hadi; González-Berdullas, P; Eda Silva, JCG; Pereira, DM; da Silva, LP. Corresponding author: da Silva, LP. "Comparative investigation into the anticancer activity of analogs of marine coelenterazine and coelenteramine". Bioorganic Chemistry 144 (2024): 107083. http://dx.doi.org/10.1016/j.bioorg.2023.107083.
    Published • 10.1016/j.bioorg.2023.107083
  3. Silva, Sónia; Teixeira, Catia; Dias, Maria Celeste; Pereira, Renato B.; Paula Gomes; Artur M. S. Silva. Corresponding author: Silva, Sónia. "Novel approach to deal with water deficit stress in crops using a natural antioxidant peptide". (2024):
    Under revision
  4. Olim, P; Pereira, RB; Fernandes, MJG; Natal, CM; Coelho, JRA; Fortes, AG; Gonçalves, MST; Pereira, DM. Corresponding author: Pereira, RB. "Structural modification of naturally-occurring phenolics as a strategy for developing cytotoxic molecules towards cancer cells". Archiv der Pharmazie 356 12 (2023): e2300294. https://onlinelibrary.wiley.com/doi/10.1002/ardp.202300294.
    Published • 10.1002/ardp.202300294
  5. Wu, Dongze; Jin, Yingzhao; Xing, Yuhan; Abate, Melsew Dagne; Abbasian, Mohammadreza; Abbasi-Kangevari, Mohsen; Abbasi-Kangevari, Zeinab; et al.. "Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019". eClinicalMedicine 64 (2023): 102193. http://dx.doi.org/10.1016/j.eclinm.2023.102193.
    Published • 10.1016/j.eclinm.2023.102193
  6. Shin, Youn Ho; Hwang, Jimin; Kwon, Rosie; Lee, Seung Won; Kim, Min Seo; Shin, Jae Il; Yon, Dong Keon; et al.. "Global, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019". Allergy: European Journal of Allergy and Clinical Immunology 78 8 (2023): 2232-2254. http://dx.doi.org/10.1111/all.15807.
    Published • 10.1111/all.15807
  7. Rechek, H; Haouat, A; Pinto, DCGA; Pereira, DM; Pereira, RB; Válega, MSGA; Cardoso, SM; Silva, AMS. Corresponding author: Silva, AMS. "A comparative analysis between the phenolic content, key enzyme inhibitory potential, and cytotoxic activity of Arum italicum Miller in Two Different Organs". International Journal of Plant Biology 14 (2023): 520-532. https://www.mdpi.com/2037-0164/14/2/41.
    Open access • Published • 10.3390/ijpb14020041
  8. Magalhães, C; Ducic, T; Pereira, RB; González-Berdullas, P; Rodríguez-Borges, JE; Pereira, DM; Esteves da Silva, J; Algarra, M; Pinto da Silva, L. Corresponding author: Pinto da Silva, L. "Synchrotron-based FTIR evaluation of biochemical changes in cancer and noncancer cells induced by brominated marine coelenteramine". Archives of Biochemistry and Biophysics 743 (2023): 109660. https://www.sciencedirect.com/science/article/pii/S0003986123001595?via%3Dihub.
    Published • 10.1016/j.abb.2023.109660
  9. Momtazmanesh, Sara; Moghaddam, Sahar Saeedi; Ghamari, Seyyed-Hadi; Rad, Elaheh Malakan; Rezaei, Negar; Shobeiri, Parnian; Aali, Amirali; et al.. "Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019". eClinicalMedicine 59 (2023): 101936. http://dx.doi.org/10.1016/j.eclinm.2023.101936.
    Published • 10.1016/j.eclinm.2023.101936
  10. Pereira, RB; Rahali, FZ; Nehme, R; Falleh, H; Jemaa, MB; Sellami, IH; Ksouri, R; et al. Corresponding author: Pereira, RB. "Anti-inflammatory activity of essential oils from Tunisian aromatic and medicinal plants and their major constituents in THP-1 macrophages". Food Research International 167 (2023): 112678. http://dx.doi.org/10.1016/j.foodres.2023.112678.
    Published • 10.1016/j.foodres.2023.112678
  11. Rechek, H; Haouat, A; Hamaidia, K; Pinto, DCGA; Boudiar, T; Válega, MSGA; Pereira, DM; Pereira, RB; Silva, AMS. "Inula viscosa (L.) Aiton ethanolic extract inhibits the growth of human AGS and A549 cancer cell lines". Chemistry & Biodiversity 20 3 (2023): e2022008. http://dx.doi.org/10.1002/cbdv.202200890.
    Published • 10.1002/cbdv.202200890
  12. Lukasiuk, K; Lason, W. "Emerging molecular targets for anti-epileptogenic and epilepsy modifying drugs". International Journal of Molecular Sciences 24 3 (2023): 2928. http://dx.doi.org/10.3390/ijms24032928.
    Open access • Published • 10.3390/ijms24032928 • Editor
  13. Bada, L; Pereira, RB; Pereira, DM; Lores, M; Celeiro, M; Quezada, E; Uriarte, E; Gil-Longo, J; Viña, D. "Phytochemical analysis and antiproliferative activity of Ulex gallii Planch. (Fabaceae), a medicinal plant from Galicia (Spain)". Molecules 28 1 (2023): 351. http://dx.doi.org/10.3390/molecules28010351.
    Published • 10.3390/molecules28010351
  14. Ricardo G. G. Coelho; Renato Pereira; Rita Rodrigues; David Pereira; Elisabete M. S. Castanheira; A. Gil Fortes; Maria José G. Fernandes; M Sameiro T Gonçalves. "Nanoencapsulation of 3-Chloropropylaminobenzoate Derivatives with Potential Insecticidal Activity". Chemistry Proceedings (2022): https://www.mdpi.com/2673-4583/12/1/91.
    10.3390/ecsoc-26-13719
  15. BenJemaa, M; Rahali, FZ; Falleh, H; Beji-Serairi, R; Megdiche-Ksouri, W; Hamrouni, I; Hammami, M; et al. "Essential oil stabilisation by response surface methodology (RSM): nanoemulsion formulation, physicochemical, microbiological, and sensory investigations". Molecules 27 21 (2022): 7330. http://dx.doi.org/10.3390/molecules27217330.
    Published • 10.3390/molecules27217330
  16. Fernandes, MJG; Pereira, RB; Rodrigues, ARO; Vieira, TF; Fortes, AG; Pereira, DM; Sousa, SF; Gonçalves, MST; Castanheira, EMS. Corresponding author: Castanheira, EMS. "Liposomal formulations loaded with a eugenol derivative for application as insecticides: encapsulation studies and in silico identification of protein targets". Nanomaterials 12 20 (2022): 3583. http://dx.doi.org/10.3390/nano12203583.
    Open access • Published • 10.3390/nano12203583
  17. Oliveira, CBP; Pereira, RB; Pereira, DM; Hilliou, L; Castro, TG; Martins, JA; Jervis, PJ; Ferreira, PMT. "Aryl-capped lysine-dehydroamino acid dipeptide supergelators as potential drug release systems". International Journal of Molecular Sciences 23 19 (2022): 11811. http://dx.doi.org/10.3390/ijms231911811.
    Open access • Published • 10.3390/ijms231911811
  18. Veloso, SRS; Gomes, V; Mendes, SLF; Hilliou, L; Pereira, RB; Pereira, DM; Coutinho, PJG; et al. "Plasmonic lipogels: driving co-assembly of composites with peptide-based gels for controlled drug release". Soft Matter 18 44 (2022): 8384-8397. http://dx.doi.org/10.1039/d2sm00926a.
    Published • 10.1039/d2sm00926a
  19. Tran, Khanh Bao; Lang, Justin J; Compton, Kelly; Xu, Rixing; Acheson, Alistair R; Henrikson, Hannah Jacqueline; et al.. "The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 400 10352 (2022): 563-591. http://dx.doi.org/10.1016/s0140-6736(22)01438-6.
    Published • 10.1016/s0140-6736(22)01438-6
  20. González-Berdullas, P; Pereira, RB; Teixeira, C; Silva, JP; Magalhães, CM; Rodríguez-Borges, JE; Pereira, DM; Esteves da Silva, JCG; Pinto da Silva, L. "Discovery of the anticancer activity for lung and gastric cancer of a brominated coelenteramine analog". International Journal of Molecular Sciences 23 15 (2022): 8271. http://dx.doi.org/10.3390/ijms23158271.
    Published • 10.3390/ijms23158271
  21. Coelho, CMM; Pereira, RB; Vieira, TF; Teixeira, CM; Fernandes, MJG; Rodrigues, ARO; Pereira, DM; et al. "Synthesis, computational and nanoencapsulation studies on eugenol-derived insecticides". New Journal of Chemistry 46 30 (2022): 14375-14387. http://dx.doi.org/10.1039/d2nj01893d.
    Published • 10.1039/d2nj01893d
  22. Oliveira, CBP; Veloso, SRS; Castanheira, EMS; Figueiredo, PR; Carvalho, ATP; Hilliou, L; Pereira, RB; et al. "An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration-prepared from a known folate receptor ligand". Soft Matter 18 20 (2022): 3955-3966. http://dx.doi.org/10.1039/d2sm00121g.
    Published • 10.1039/d2sm00121g
  23. Sharma, Rajesh; Abbasi-Kangevari, Mohsen; Abd-Rabu, Rami; Abidi, Hassan; Adhikari, Sangeet; Advani, Shailesh M; et al.. "Global, regional, and national burden of colorectal cancer and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet Gastroenterology & Hepatology 7 7 (2022): 627-647. http://dx.doi.org/10.1016/s2468-1253(22)00044-9.
    Published • 10.1016/s2468-1253(22)00044-9
  24. Teixeira, C; Pereira, RB; Pinto, NFS; Coelho, CMM; Fernandes, MJG; Fortes, AG; Gonçalves, MST; Pereira, DM. "Eugenol ß-amino/ß-alkoxy alcohols with selective anticancer activity". International Journal of Molecular Sciences 23 7 (2022): 3759. http://dx.doi.org/10.3390/ijms23073759.
    Published • 10.3390/ijms23073759
  25. Armocida, Benedetta; Monasta, Lorenzo; Sawyer, Susan; Bustreo, Flavia; Segafredo, Giulia; Castelpietra, Giulio; et al.. "Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019". The Lancet Child & Adolescent Health 6 6 (2022): 367-383. http://dx.doi.org/10.1016/s2352-4642(22)00073-6.
    Published • 10.1016/s2352-4642(22)00073-6
  26. Lipinski, PFJ ; Matalinska, J. "Fentanyl Structure as a Scaffold for Opioid/Non-Opioid Multitarget Analgesics". International Journal of Molecular Targets 23 5 (2022): 2766. https://www.mdpi.com/1422-0067/23/5/2766.
    Published • Editor
  27. Witkowska, E; Godlewska, M; Osiejuk, J; Gatarz, S; Wilenska, B; Kosinska, K; Starnowska-Sokól, J; et al. "Bifunctional opioid/melanocortin peptidomimetics for Use in neuropathic pain: variation in the type and length of the linker connecting the two pharmacophores". International Journal of Molecular Sciences 23 2 (2022): 674. http://dx.doi.org/10.3390/ijms23020674.
    Open access • Published • 10.3390/ijms23020674 • Editor
  28. Kocarnik, JM; Compton, K; Dean, FE; Fu, W; Gaw, BL; Henrikson, HJ; Lu, D; et al. "Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019". JAMA Oncology (2021): http://dx.doi.org/10.1001/jamaoncol.2021.6987.
    Published • 10.1001/jamaoncol.2021.6987
  29. Alvarez, EM; Force, LM; Xu, R; Compton, K; Lu, D; Henrikson, HJ; Kocarnik, JM; et al.. "The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet Oncology 23 1 (2021): 27-52. http://dx.doi.org/10.1016/s1470-2045(21)00581-7.
    Published • 10.1016/s1470-2045(21)00581-7
  30. Pereira, RB; Pinto, NFS; Fernandes, MJG; Vieira, TF; Rodrigues, ARO; Pereira, DM; Sousa, SF; et al. "Amino alcohols from eugenol as potential semisynthetic insecticides: chemical, biological, and computational insights". Molecules 26 21 (2021): 6616. http://dx.doi.org/10.3390/molecules26216616.
    Open access • Published • 10.3390/molecules26216616
  31. Natal, CM; Fernandes, MJG; Pinto, NFS; Pereira, RB; Vieira, TF; Rodrigues, ARO; Pereira, DM; et al. "New carvacrol and thymol derivatives as potential insecticides: synthesis, biological activity, computational studies and nanoencapsulation". RSC Advances 11 54 (2021): 34024-34035. http://dx.doi.org/10.1039/d1ra05616f.
    Published • 10.1039/d1ra05616f
  32. Amorim, C; Veloso, SRS; Castanheira, EMS; Hilliou, L; Pereira, RB; Pereira, DM; Martins, JA; Jervis, PJ; Ferreira, PMT. "Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems". Gels 7 2 (2021): 52. http://dx.doi.org/10.3390/gels7020052.
    Published • 10.3390/gels7020052
  33. Jervis, PJ; Hilliou, L; Pereira, RB; Pereira, DM; Martins, JA; Ferreira, PMT. "Evaluation of a model photo-caged dehydropeptide as a stimuli-responsive supermolecular hydrogel". Nanomaterials 11 3 (2021): 704.
    Published • 10.3390/nano11030704
  34. Nehme, R; Andrés, S; Pereira, RB; Jemaa, MB; Bouhallab, S; Ceciliani, F; López, S; et al. "Essential Oils in Livestock: From Health to Food Quality". Antioxidants 10 2 (2021): 330. http://dx.doi.org/10.3390/antiox10020330.
    Open access • Published • 10.3390/antiox10020330
  35. Pech-Puch, D; Joseph-Nathan, P; Burgueño-Tapia, E; González-Salas, C; Martínez-Matamoros, D; Pereira, DM; Pereira, RB; Jiménez, C; Rodríguez, J. "Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian Briareum asbestinum". Scientific Reports 11 1 (2021): 496. http://dx.doi.org/10.1038/s41598-020-79774-1.
    Published • 10.1038/s41598-020-79774-1
  36. Fernandes, MJG; Pereira, RB; Pereira, DM; Fortes, AG; Castanheira, EMS; Gonçalves, MST. "New Eugenol Derivatives with Enhanced Insecticidal Activity". International Journal of Molecular Sciences 21 23 (2020): 9257. https://doi.org/10.3390/ijms21239257.
    Published • 10.3390/ijms21239257
  37. Gomes, NGM; Valentão, P; Andrade, PB; Pereira, RB. Corresponding author: Pereira, RB. "Plitidepsin to treat multiple myeloma". Drugs of Today 56 5 (2020): 1-11.
    Published • 10.1358/dot.2020.56.5.3135886
  38. Nelson G. M. Gomes; Renato B. Pereira; Paula B. Andrade; Patrícia Valentão. "Double the Chemistry, Double the Fun: Structural Diversity and Biological Activity of Marine-Derived Diketopiperazine Dimers". Marine Drugs 17 10 (2019): 551-551. https://doi.org/10.3390/md17100551.
    Published • 10.3390/md17100551
  39. Pereira, RB; Pereira, DM; Jiménez, C; Rodríguez, J; Nieto, RM; Videira, RA; Silva, OMD; Andrade, PB; Valentão, P. "Anti-Inflammatory Effects of 5a,8a-Epidioxycholest-6-en-3ß-ol, a Steroidal Endoperoxide Isolated from Aplysia depilans, Based on Bioguided Fractionation and NMR Analysis". Marine Drugs 17 6 (2019): 330. https://doi.org/10.3390/md17060330.
    Published • 10.3390/md17060330
  40. Pereira, RB; Evdokimov, NM; Lefranc, F; Valentão, P; Kornienko, A; Pereira, DM; Andrade, PB; Gomes, NGM. "Marine-Derived Anticancer Agents: Clinical Benefits, Innovative Mechanisms, and New Targets". Marine Drugs 17 6 (2019): 329. https://doi.org/10.3390/md17060329.
    Published • 10.3390/md17060329
  41. Pereira, RB; Almeida, AA; Pereira, DM; Silva, OMD; Andrade, PB; Pinto, E; Valentão, P. "Trace elements in wild edible Aplysia species: Relationship with the desaturation-elongation indexes of fatty acids". Chemosphere 208 (2018): 682-690. http://dx.doi.org/10.1016/j.chemosphere.2018.06.034.
    Published • 10.1016/j.chemosphere.2018.06.034
  42. Pereira, RB; Pinto, DCGA; Pereira, DM; Gomes, NGM; Silva, AMS; Andrade, PB; Valentão, P. "UHPLC-MS/MS profiling of Aplysia depilans and assessment of its potential therapeutic use: Interference on iNOS expression in LPS-stimulated RAW 264.7 macrophages and caspase-mediated pro-apoptotic effect on SH-SY5Y cells". Journal of Functional Foods 37 (2017): 164-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026412540&partnerID=MN8TOARS.
    Published • 10.1016/j.jff.2017.07.053
  43. Pereira, R.B.; Andrade, P.B.; Valentão, P.. "Chemical diversity and biological properties of secondary metabolites from sea hares of Aplysia genus". Marine Drugs 14 2 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84960109402&partnerID=MN8TOARS.
    Published • 10.3390/md14020039
  44. Pereira, RB; Andrade, PB; Valentão, P. "A Comprehensive View of the Neurotoxicity Mechanisms of Cocaine and Ethanol". Neurotoxicity Research 28 3 (2015): 253-267. http://dx.doi.org/10.1007/s12640-015-9536-x.
    Published • 10.1007/s12640-015-9536-x
  45. Pereira, RB; Taveira, M; Valentão, P; Sousa, C; Andrade, PB. "Fatty acids from edible sea hares: anti-inflammatory capacity in LPS-stimulated RAW 264.7 cells involves iNOS modulation". RSC Advances 5 12 (2015): 8981-8987. http://dx.doi.org/10.1039/c4ra14333g.
    Published • 10.1039/c4ra14333g
  46. Pereira, RB; Sousa, C; Costa, A; Andrade, PB; Valentão, P. "Glutathione and the Antioxidant Potential of Binary Mixtures with Flavonoids: Synergisms and Antagonisms". Molecules 18 8 (2013): 8858-8872. http://dx.doi.org/10.3390/molecules18088858.
    Published • 10.3390/molecules18088858
  47. Silva, G; Pereira, RB; Valentão, P; Andrade, PB; Sousa, C. "Distinct fatty acid profile of ten brown macroalgae". Brazilian Journal of Pharmacognosy 23 4 (2013): 608-613.
    Published • 10.1590/S0102-695X2013005000048
Journal issue
  1. Pereira, RB; Pereira, DM. "Dual Targeting as a Strategy to Counteract Chronic Diseases". International Journal of Molecular Sciences (2020): https://www.mdpi.com/journal/ijms/special_issues/dual_targeting.
    Invited editor
Thesis / Dissertation
  1. Pereira, RB. "Bioprospecting Aplysia sea hares as valuable sources of bioactive molecules". PhD, Universidade do Porto Faculdade de Farmácia, 2019. https://repositorio-aberto.up.pt/handle/10216/125008.

Intellectual property

Patent
  1. Pereira, RB; Pereira, DM; Gonçalves, MST; Fortes, AG; Coutinho, EMS. 2021. "Low toxicity compound suitable for use as insecticide and method of producing said compounds PCT/IB2021/053422".
    Pending
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/09/08 Nutritional and health benefits of essential oils in dairy cows 73rd Annual Meeting of the European Federation of Animal Science
Portuguese Association of Animal Science (APEZ) under the patronage of the Ministry of Agriculture, Rural Development and Fisheries of Portugal (Porto, Portugal)
2022/05/04 Plant extracts as biopesticides: chemistry, bioactivity and nanoencapsulation IJUP 15 ed.
Universidade do Porto (Porto, Portugal)
2021/09/27 In vitro evaluation of bioactive molecules and extracts 2nd MilkQua Project Steering Board Meeting
Università degli Studi di Milano Statale (Milan, Italy)
2021/08/11 Synthesis of alkoxy alcohols from eugenol and their biological activity against Sf9 cell line Virtual Conference on Chemistry and its Applications (VCCA-2021)
Computational Chemistry Group of the University of Mauritius (Reduit, Mauritius)
2021/08/10 Eugenol epoxide derivatives: synthesis and biological activity Virtual Conference on Chemistry and its Applications (VCCA-2021)
Computational Chemistry Group of the University of Mauritius (Reduit, Mauritius)
2021/08/09 Synthesis, insecticidal activity and nanoencapsulation studies of amino alcohols derivatives from eugenol Virtual Conference on Chemistry and its Applications (VCCA-2021)
Computational Chemistry Group of the University of Mauritius (Reduit, Mauritius)
2021/05/07 New semisynthetic derivatives of thymol, eugenol, ginkgolic acid and 6-hydroxyflavanone with enhanced cytotoxic activity IJUP 14 ed.
University of Porto
2020/08 Synthesis and insecticidal activity of O-alkylated derivatives of eugenol Virtual Conference on Chemistry and its Applications
(Held online due to COVID-19)
2020/08 N-Alkylated derivatives of anthranilic acid as potential bioinsecticides Virtual Conference on Chemistry and its Applications
(Held online due to COVID-19)
2016/06/15 Blue Biotechnology: Unlocking the Potential of Oceans and Seas 1st Workshop Novel Compounds from Renewable Sources
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (Lisbon, Portugal)
2016/06/01 Box-Behnken design applied to exotic fruits: enhancing betacyanins and phenolic compounds extraction from the peel CIPAM 2016 - 6th International Congress of Aromatic and Medicinal Plants
(Coimbra, Portugal)
2016/02/18 Anti-inflammatory activity of aqueous extracts of sea anemones in macrophages 9th Meeting of Young Researchers of University of Porto
(Porto, Portugal)
2015/12/02 Fatty acids from edible sea hares: anti-inflammatory capacity in LPS-stimulated RAW 264.7 cells involves iNOS modulation 11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry
Portuguese Chemical Society (Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/09 - Current Evaluation of lipoxygenase inhibitory activity of novel eugenol derivatives
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade Federal do Maranhão, Brazil

Universidade do Porto Faculdade de Farmácia, Portugal
2020/09 - 2021/07 "New semisynthetic derivatives of thymol, eugenol, ginkgolic acid and 6-hydroxyflavanone: evaluation of cytotoxic activity"
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/05/18 - 2019/05/18 Monitor of the organizing committee of the event "Nature serving Pharmacy: the therapeutic potential of plants" within the celebration of the International Fascination of Plants Day (2019/05/18 - 2019/05/18)
Workshop
 Universidade do Porto Faculdade de Farmácia, Portugal
2015/11/28 - 2015/11/28 Member of the organizing committee of the event "Semana da Ciência e da Tecnologia 2015" promoted by the "Programa Ciência Viva" (2015/11/28 - 2015/11/28)
Workshop
 Universidade do Porto Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/07/26 Práticas etnofarmacológicas na Guiné-Bissau: Estudo fitoquímico e biológico de espécies com atividade citotóxica em células de cancro
(Thesis) Arguer
 Vera Alexandra de Macedo Ribeiro (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/07/28 Conservantes alimentares baseados em compostos bioativos
(Thesis) Main arguer
 Diana Margarida Correia Pereira (Master)
Universidade do Minho Escola de Ciências, Portugal
2020/07/28 "Interações entre carcinogénicos ambientais - uma abordagem genotóxica e metabolómica"
(Thesis) Main arguer
 Vânia Raquel Da Cunha Monteiro (Other)
Instituto Universitário de Ciências da Saúde, Portugal

Association member

Society Organization name Role
2015/09/21 - Current Sociedade Portuguesa de Química Member

Committee member

Activity description
Role 		Institution / Organization
2021/06/10 - Current Review Editor on the Editorial Board of Ethnopharmacology (specialty section of Frontiers in Pharmacology).
Member
 Frontiers Media SA, Switzerland
2021/04/09 - Current International Journal of Molecular Sciences: Member of the Reviewer Board
Member
 MDPI AG, Switzerland

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020 - Current Continuing Training Course "Medicinal Plants: Challenges and Opportunities" (Summer School) Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Current Course Unit - "Tópicos de Farmacognosia" PhD Program in Marine Biotechnology and Aquaculture (Doutoramento) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2021/09/06 - 2022/02/19 Practical classes: Pharmaceutical Technology IV Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2015/09 - 2019/09 Course Unit "Bioactivity of Natural Matrices" Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2023/03/03 - Current BioChem (2673-6411) MDPI
2022/12/05 - Current Life (2075-1729) MDPI
2022/07/09 - Current Pharmaceuticals (1424-8247) MDPI
2022/06/15 - Current Antibiotics (2079-6382) MDPI
2022/03/31 - Current Antioxidants (2076-3921) MDPI
2022/03/15 - Current Cells (2073-4409) MDPI
2021/12/09 - Current Medicines (2305-6320) MDPI
2021/08/12 - Current PLoS One (1932-6203) PUBLIC LIBRARY SCIENCE
2021/08/02 - Current Plants (2223-7747) MDPI
2021/06/19 - Current Processes (2227-9717) MDPI
2021/04/09 - Current Frontiers in Pharmacology (1663-9812) Frontiers
2021/03/24 - Current Foods (2304-8158) MDPI
2020/12/22 - Current Marine drugs (1660-3397) MDPI
2020/12/19 - Current Molecules (1420-3049) MDPI
2019/09/29 - Current Chemical papers (1336-9075) Springer

Mentoring / Tutoring

Topic Student name
2022/02/01 - Current Bioresponsive nanomaterials for combined chemo/photodynamic therapy of cancer and biomedical imaging Carla Marisa Pacheco Magalhães (PhD)
2020/09 - Current Cytotoxicity studies of phytochemicals and/or synthetic natural Cláudia Sofia Machado Teixeira (MSc student)
2020/05 - Current Phytochemical and pharmacological study of Galician medicinal plants Lucía Bada Díaz (PhD student)
2020/09 - 2021/07 Food preservatives based on bioactive compounds Diana Margarida Correia Pereira (MSc student)
Distinctions

Award

2023 Nanomaterials 2022 Best Cover Award
MDPI AG, Switzerland

Other distinction

2015 PhD grant in PhD Programme in Medicines and Pharmaceutical Innovation funded by FCT
Fundação para a Ciência e a Tecnologia, Portugal