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Ana Sofia Rodrigues is a science and project manager at Universidade de Coimbra, Faculdade de Medicina. Although she has only started her career as a Science Manager in 2020, she has supported over 90 grant applications for different funding schemes and funding entities, both International and National. Her management support activities during pre-award and post- award to researchers, benefit with a perspective of a former researcher with the objectivity and integrated vision that a Science and Project Manager must have. Her scientific background, routed in a Bachelor degree in Biology, a Masters degree in Cellular Biology and a PhD in Biomedicine and Experimental Biology, provided her with skills not only at project coordination/management and mentoring students, but also, in implementing and optimizing different processes with an efficient resolution of the roadblocks that appeared along the way. Throughout this journey not only she had to master literature from different areas of research but also successfully implement a Stem Cell laboratory from scratch in the middle of her PhD representing a major challenge. Ana Sofia's career counts with almost twelve years of experience echoed in 16 peer reviewed papers, 2 book chapters and 7 oral communications besides several poster communications in a total of 524 citations (Scopus ID24353179000) and an h index of 12 (in google scholar).
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Identification

Personal identification

Full name
Ana Sofia Jesus Rodrigues

Citation names

  • Rodrigues, Ana Sofia

Author identifiers

Ciência ID
EA13-3E7C-D0EB
ORCID iD
0000-0001-7060-879X

Email addresses

  • sofiarodrigues@fmed.uc.pt (Professional)

Addresses

  • Pólo das Ciências da Saúde, Unidade Central, Azinhaga de Santa Comba, 3000-548, Coimbra, Coimbra, Portugal (Professional)

Websites

  • http://orcid.org/0000-0001-7060-879X (Professional)
  • linkedin.com/in/ana-sofia-rodrigues-a1665392 (Professional)
  • http://www.scopus.com/authid/detail.url?authorId=24353179000 (Professional)

Knowledge fields

  • Social Sciences - Economics and Business - Business and Management
  • Medical and Health Sciences
  • Medical and Health Sciences - Medical Biotechnology
  • Natural sciences - Biological Sciences - Reproductive Biology
  • Natural sciences - Biological Sciences - Developmental Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Italian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2014
Concluded
 PhD (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"The role of metabolism and mitochondrial function in embryonic stem cells." (THESIS/DISSERTATION)
 Distincao e Louvor
2008
Concluded
 M.S. (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Uncoupling protein 2 modulates mitochondrial proton leak and reactive oxygen species in a tissue specific manner" (THESIS/DISSERTATION)
 A
2006
Concluded
 B.Sc. Biology (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"n/a" (THESIS/DISSERTATION)
 15
Affiliation

Others

Category
Host institution 		Employer
2020/01 - Current Science and Technology Manager Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/09/01 - 2019/12/31 Post Doctoral fellow with a FCT scholarship #SFRH/BPD/119367/2016 Fundação para a Ciência e a Tecnologia, Portugal
2017/06/01 - 2017/08/31 Post-Doctoral Fellow in the Project HealthyAging 2020 with a scholarship BID 6.1.1 Universidade de Coimbra, Portugal
2014/04/01 - 2015/09/30 Post-Doctoral Fellow in the project Projeto Mais Centro - "Stemcell based platforms for Regenerative and Therapeutic Medicine¿ (CENTRO-07-ST24-FEDER-002008) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/07/21 - 2014/07/25 Lecturer: II Cell culture and tissue training course. http://www.uc.pt/fmuc/cimago/cursos/IICellCultureTissueTrainingCourse. Hospitais da Universidade de Coimbra Centro de Cirurgia Cardiotorácica, Portugal
2013/12/08 - 2013/12/13 Teacher Assistant: FRONTIERS IN STEM CELLS IN CANCER (FriSC2). http://www.pdc.magee.edu/outreach.htm. An annual advanced training course that trains promising physician and scientists. University of Pittsburgh Medical Center, United States
2013/12/02 - 2013/12/08 Teacher Assistant: Rehabilitative and Regenerative Medicine for Minority Health and Health Disparities (REMEDY) http://www.pdc.magee.edu/outreach.htm. A FRONTIERS Advanced Training Course. University of Pittsburgh Medical Center, United States
2013/06/01 - 2013/10/31 Researcher in the project PTDC/QUI-BIQ/120652/2010 "Role of the pyruvate dehydrogenase Kinase metabolic swith in pluripotency insights into cancer and stem cell biology". Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/10/01 - 2012/09/30 Invidual PhD Scholarship granted by FCT with the reference: SFRH/ BD/ 33463/ 2008. Fundação para a Ciência e a Tecnologia, Portugal
2011/10/02 - 2011/10/08 Teacher Assistant: The Frontiers in Stem Cells and Regeneration Course (FrHESC) http://www.pdc.magee.edu/outreach.htm. Brown University Marine Biological Laboratory Biological and Environmental Sciences, United States
2009/04/01 - 2010/08/31 ¿¿Visiting Ph.D. Student University of Pittsburgh Medical Center, United States
Projects

Grant

Designation Funders
2012/05 - 2015/08 Role of the pyruvate dehydrogenase kinase metabolic switch in pluripotency: insights into cancer and stem cell biology.
Provided by PTCRIS: 120652
 Fundação para a Ciência e a Tecnologia
Outputs

Publications

Journal article
  1. Rodrigues, Ana Sofia. "Effects of DMSO on the Pluripotency of Cultured Mouse Embryonic Stem Cells (mESCs).". Stem cells international (2020): https://europepmc.org/articles/PMC7584961.
    10.1155/2020/8835353
  2. Rodrigues, Ana Sofia. "Metabolic characterization of a paused-like pluripotent state". Biochimica et Biophysica Acta (BBA) - General Subjects (2020): http://dx.doi.org/10.1016/j.bbagen.2020.129612.
    10.1016/j.bbagen.2020.129612
  3. Rodrigues, Ana Sofia. "Stem metabolism: Insights from oncometabolism and vice versa". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2020): http://dx.doi.org/10.1016/j.bbadis.2020.165760.
    10.1016/j.bbadis.2020.165760
  4. Rodrigues, Ana. "Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis Software.". Stem cell reports (2017): http://europepmc.org/abstract/med/28712847.
    10.1016/j.stemcr.2017.06.006
  5. Correia M; Perestrelo T; Rodrigues AS; Ribeiro MF; Pereira SL; Sousa MI; Ramalho-Santos J. "Sirtuins in metabolism, stemness and differentiation.". (2017): http://europepmc.org/abstract/med/27614149.
    10.1016/j.bbagen.2016.09.008
  6. Correia M; Rodrigues AS; Perestrelo T; Pereira SL; Ribeiro MF; Sousa MI; Ramalho-Santos J. "Different concentrations of kaempferol distinctly modulate murine embryonic stem cell function.". (2016): http://europepmc.org/abstract/med/26683311.
    10.1016/j.fct.2015.12.011
  7. Fonseca NA; Rodrigues AS; Rodrigues-Santos P; Alves V; Gregório AC; Valério-Fernandes Â; Gomes-da-Silva LC; et al. "Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination.". (2015): http://europepmc.org/abstract/med/26283155.
    10.1016/j.biomaterials.2015.08.007
  8. Sousa MI; Rodrigues AS; Pereira S; Perestrelo T; Correia M; Ramalho-Santos J. "Mitochondrial Mechanisms of Metabolic Reprogramming in Proliferating Cells.". (2015): http://europepmc.org/abstract/med/25973982.
    10.2174/0929867322666150514095718
  9. Rodrigues AS; Pereira SL; Correia M; Gomes A; Perestrelo T; Ramalho-Santos J. "Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells.". (2015): http://europepmc.org/abstract/med/26266544.
    10.1371/journal.pone.0135617
  10. Rodrigues AS; Correia M; Gomes A; Pereira SL; Perestrelo T; Sousa MI; Ramalho-Santos J. "Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency.". (2015): http://europepmc.org/abstract/med/26147621.
    10.1371/journal.pone.0131663
  11. Pereira SL; Rodrigues AS; Sousa MI; Correia M; Perestrelo T; Ramalho-Santos J. "From gametogenesis and stem cells to cancer: common metabolic themes.". (2014): http://europepmc.org/abstract/med/25013216.
    10.1093/humupd/dmu034
  12. Pereira SL; Grãos M; Rodrigues AS; Anjo SI; Carvalho RA; Oliveira PJ; Arenas E; Ramalho-Santos J. "Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency.". (2013): http://europepmc.org/abstract/med/24312632.
    10.1371/journal.pone.0082095
  13. Varum S; Rodrigues AS; Moura MB; Momcilovic O; Easley CA 4th; Ramalho-Santos J; Van Houten B; Schatten G. "Energy metabolism in human pluripotent stem cells and their differentiated counterparts.". (2011): http://europepmc.org/abstract/med/21698063.
    10.1371/journal.pone.0020914
  14. Rodrigues AS; Lacerda B; Moreno AJ; Ramalho-Santos J. "Proton leak modulation in testicular mitochondria affects reactive oxygen species production and lipid peroxidation.". (2010): http://europepmc.org/abstract/med/20235330.
    10.1002/cbf.1644
  15. Gamboa S; Rodrigues AS; Henriques L; Batista C; Ramalho-Santos J. "Seasonal functional relevance of sperm characteristics in equine spermatozoa.". (2010): http://europepmc.org/abstract/med/20083300.
    10.1016/j.theriogenology.2009.11.023
  16. Amaral S; Mota P; Rodrigues AS; Martins L; Oliveira PJ; Ramalho-Santos J. "Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak.". (2008): http://europepmc.org/abstract/med/19041646.
    10.1016/j.febslet.2008.11.020
  17. Morte MI; Rodrigues AM; Soares D; Rodrigues AS; Gamboa S; Ramalho-Santos J. "The quantification of lipid and protein oxidation in stallion spermatozoa and seminal plasma: seasonal distinctions and correlations with DNA strand breaks, classical seminal parameters and stallion fertility.". (2008): http://europepmc.org/abstract/med/17451892.
    10.1016/j.anireprosci.2007.03.020
  18. Karen Mascaro Gonçalves da Silva; Sandra Cristina Gamboa; Ana Sofia Rodrigues; João Ramalho Santos; Maria Madalena Pessoa Guerra. "Adição de piruvato de sódio e trolox ao diluidor utilizado para congelação de sêmen de garanhões férteis e subférteis". Cienc. Rural 38 8 (2008): 2271-2277. http://dx.doi.org/10.1590/s0103-84782008000800028.
    10.1590/s0103-84782008000800028

Other

Other output
  1. From Oocytes and Pluripotent Stem Cells to Fully Differentiated Fates: (Also) a Mitochondrial Odyssey. 2012. João Ramalho-Santos; Ana Sofia Rodrigues. http://dx.doi.org/10.1007/978-1-62703-101-1_4.
    10.1007/978-1-62703-101-1_4
Distinctions

Other distinction

2017 Best Oral Communication in the 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies