Andreia Brandão (EA13-D4E6-CDE1)

Curriculum Vitae

Andreia Brandão

Andreia Brandão has extensive experience in population genetics, bioinformatics, and cancer genomics, with a degree in Genetics and Biotechnology and an MSc in Technological Comparative Molecular Genetics. She has a PhD in Biomedical Sciences, specializing in population genetics and bioinformatics, where she focused on the analysis of mitochondrial DNA (mtDNA) and genome-wide data to identify human genetic variation in Southeast Asian populations. She has worked on various research projects in different fields, including molecular genetics, microbiology, proteomics, population genomics, phylogenetics, and bioinformatics, at different universities and research institutions in Portugal, Spain, and the UK. She has several years of postdoctoral experience combining bioinformatics, population genetics, and cancer genomics at the Research Center of the Portuguese Oncology Institute of Porto (CI-IPOP). Here she has implemented a computational cancer genomics research line focusing on the analysis of both high-throughput genomics (targeted-NGS, whole-genome/exome) and transcriptomics data (RNAseq) from cancer patients to help characterize the inherited mutations associated with cancer predisposition, as well as the pattern of somatic genetic alterations that might have implications on tumor progression and therapy response. She often mentors MSc and PhD students, and actively participates in scientific meetings and workshops. Her in-depth experience in bioinformatics resources, large-scale databases (populational and pan-cancer), and data analysis and visualization (Python and R), has rendered 12 co-authorships in peer-reviewed Q1 journals (4 as first author) and several oral and poster communications in international meetings. She is on the Editorial Board of the Cancer Genetics and Oncogenomics (Frontiers in Genetics), as a Review Editor, and a Guest Editor at the open-access journal, Genes. Her contributions have been recognized by awards such as the Leonardo da Vinci mobility fellowship, FCT PhD fellowship, and recently the FCT Scientific Employment Stimulus (CEEC) - Individual Call.

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Identification

Personal identification

Full name: Andreia Brandão

Citation names

Brandão, Andreia

Author identifiers

Ciência ID: EA13-D4E6-CDE1
ORCID iD: 0000-0003-0938-1543

Email addresses

andreia.aguiar.brandao@ipoporto.min-saude.pt (Professional)

Telephones

Telephone

225084000 Ext.: 5609 (Professional)

Addresses

IPO-Porto. Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Porto, Portugal (Professional)

Websites

https://www.linkedin.com/in/andreia-brand%C3%A3o-27333a25/ (Professional)

Knowledge fields

Natural sciences - Biological Sciences
Exact Sciences - Computer and Information Sciences - Bioinformatics
Natural sciences - Biological Sciences - Genetics and Heredity

Languages

Language	Speaking	Reading	Writing	Listening
French	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)
Spanish; Castilian	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Portuguese	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2024/06/11 - 2024/06/13 Concluded	COST Computational Immunogenomics Summer School (Curso de Especialização Tecnológica) Major in Immunogenomics Hospital Clínico Universitario Lozano Blesa, Spain
2023/10/31 - 2023/11/23 Concluded	R Software for Statistics in Health (Curso de Especialização Tecnológica) Escola Portuguesa de Oncologia do Porto (EPOP), Portugal
2019/03/27 - 2019/03/29 Concluded	Advanced course: introduction to programming for Bioinformatics using Java (Curso de Especialização Tecnológica) Universidade do Porto Centro de Investigação em Biodiversidade e Recursos Genéticos, Portugal
2018/01/08 - 2018/01/12 Concluded	International intensive course on cancer biology: advances in epidemiology, etiology and therapy (Curso de Especialização Tecnológica) Universidade do Porto Faculdade de Farmácia, Portugal
2017/06/26 - 2017/06/28 Concluded	Hands on course - Introduction to biological data analysis with R (Curso de Especialização Tecnológica) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2012/01/01 - 2016/06/28 Concluded	PhD in Biomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Demography of modern humans in Southeast Asia (SEA): a genetic approach" (THESIS/DISSERTATION)	Approved with distinction
2010/01/27 Concluded	Master in Technological Comparative Molecular Genetics (Mestrado) Universidade de Trás-os-Montes e Alto Douro, Portugal "Identification of bacteriocinogenic enterococci of aninal and human origin: antimicrobial activity and biochemical and genetic characterization of their bacteriocins." (THESIS/DISSERTATION)	17 values (0-20)
2008/04/16 Concluded	Genetics and Biotechnology (Licenciatura) Universidade de Trás-os-Montes e Alto Douro, Portugal "Prevalence of the C677T polymorphism of Methylenetetrahydrofolate reductase (MTHFR) in chronic hepatitis C." (THESIS/DISSERTATION)	14 values (0-20)

Affiliation

Science

	Category Host institution	Employer
2022/05/16 - Current	Contracted Researcher (Research)	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

2020/01/27 - 2022/05/15	Contracted Researcher (Research)	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2016/10/01 - 2019/12/31	Postdoc (Research)	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2012/01/01 - 2016/09/30	Researcher (Research)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2012/09/01 - 2013/07/31	Researcher (Research)	University of Huddersfield Department of Biological Sciences, United Kingdom
	University of Huddersfield Department of Biological Sciences, United Kingdom
2011/04/01 - 2011/09/30	Researcher (Research)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2010/05/01 - 2010/10/31	Researcher (Research)	Instituto Politécnico de Bragança, Portugal
	Instituto Politécnico de Bragança Escola Superior Agrária, Portugal
2008/04/01 - 2008/10/31	Researcher (Research)	Universidad Complutense de Madrid, Spain
	Universidad Complutense de Madrid, Spain
2007/11/01 - 2008/03/31	Researcher (Research)	Universidade de Trás-os-Montes e Alto Douro, Portugal
	Universidade de Trás-os-Montes e Alto Douro, Portugal
2008/01/01 - 2008/01/31	Research Trainee (Research)	Universidade de Lisboa Faculdade de Medicina, Portugal
	Universidade de Lisboa Faculdade de Medicina, Portugal

Projects

Grant

	Designation	Funders
2023/12/20 - Current	PRUNE2 gene as a novel dual-role biomarker for prostate cancer inherited predisposition and therapy response 2023.01928.RESTART Principal investigator Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022 - 2028	PATHSEARCH – Understanding the polygenic basis of hereditary predisposition to prostate cancer: a multi-omics integrative approach combining genomics and transcriptomics Project 161-CI-IPOP-154-2021 Principal investigator Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação Ongoing
2021/01/01 - 2025/12/31	Health Research Network: From Lab to Community Health LA/P/0053/2020 10.54499/LA/P/0053/2020 Researcher Universidade do Porto Faculdade de Medicina, Portugal Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade NOVA de Lisboa, Portugal Escola Superior de Enfermagem do Porto, Portugal Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal Universidade de Aveiro, Portugal Universidade da Madeira, Portugal Universidade do Algarve, Portugal Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/03/01 - 2024/08/31	REVERENT: PRE-CLINICAL VALIDATION OF A GLYCOCODE-INSPIRED VACCINE FOR BLADDER CANCER IMMUNOTHERAPY 2022.03621.PTDC Researcher Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/01/01 - 2023/12/31	IPO Porto Research Center UIDP/00776/2020 10.54499/UIDP/00776/2020 Post-doc Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2012/01/01 - 2016/06/27	Demography of modern humans in Southeast Asia (SEA): a genetic approach SFRH/BD/78990/2011 PhD Student Fellow Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal University of Huddersfield, United Kingdom	Fundação para a Ciência e a Tecnologia Concluded
2012/01 - 2015/12	DEMOGRAPHY OF MODERN HUMANS IN SOUTHEAST ASIA AND THE PORTUGUESE OVERSEAS EMPIRE INFLUENCE: A GENETIC APPROACH Provided by PTCRIS: SFRH/BD/78990/2011	Fundação para a Ciência e a Tecnologia
2013/06 - 2015/09	Genetic history and population structure in Southeast Asia Provided by PTCRIS: 132046	Fundação para a Ciência e a Tecnologia

Contract

	Designation	Funders
2022/05/16 - 2028/05/15	Leveraging multi-omics approaches under a polygenic disease model to identify potential new target biological pathways in early-onset/familial prostate cancer 2021.03835.CEECIND Principal investigator Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/07/27 - 2022/05/15	IPO Porto Research Center UIDP/00776/2020 10.54499/UIDP/00776/2020 Researcher Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/07/26 - 2021/11/21	SEGMAPP: The role of chromosome segregation machinery defects in genetic predisposition to prostate cancer PTDC/MED-GEN/28245/2017 Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/01/27 - 2021/07/27	The role of chromosome segregation machinery defects in genetic predisposition to prostate cancer PTDC/MED-GEN/28245/2017 Researcher Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2019/07/24 - 2019/12/24	Inherited prostate cancer predisposition UID/DTP/00776/2019 Post-doc Fellow Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/10/01 - 2019/06/30	Inherited predisposition to prostate cancer: finding the missing heritability by combining exome sequencing and haplotype analysis in a population with strong founder effects PTDC/DTPPIC/1308/2014 Post-doc Fellow Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/05/01 - 2016/09/30	Identifying susceptibility cancer biomarkers in inflammation-prone tumors: stomach and lung models NORTE-01-0145-FEDER-000029 Research Fellow Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Concluded
2010/05/01 - 2010/10/31	Patterns and processes of change (neutral and adaptive) in the hybridization area of bee (Apis mellifera iberiensis) of the Iberian Peninsula: an approach to integrate population genomics and landscape genetics PTDC/BIA-BEC/099640/2008 Research Fellow	Fundação para a Ciência e a Tecnologia

Outputs

Publications

Conference abstract	Lopes, Catarina; Brandão, Andreia; Costa, João; Libânio, Diogo; Mário Dinis-Ribeiro; Pereira, Carina. "Desregulação transcriptómica como uma ferramenta na deteção precoce de cancro gástrico". Paper presented in Semana Digestiva 2024, Faro, 2024. Catarina Lopes; Almeida, Tatiana C.; Andreia Brandão; Mário Dinis-Ribeiro; Pereira, Carina; Lopes, Catarina; Almeida, Tatiana; Brandão, Andreia. Corresponding author: Pereira, Carina. "Can saliva be considered a proxy of gastric tumors? A bioinformatic analysis towards biomarker discover and early diagnosis". Paper presented in European Association for Cancer Researc (EACR) 23, Torino, 2023. Accepted Almeida, Tatiana; Lopes, Catarina; Brandão, Andreia; Mário Dinis-Ribeiro; Pereira, Carina. "Revisiting the arachidonic acid pathway in gastric cancer: A transcriptomics approach towards the discovery of novel biomarkers.". Paper presented in EACR 2023 Innovative Cancer Science, Torino, 2023. Published
Conference poster	Soares, Janine; Santos, Daniela A. R.; Eiras, Mariana; Santos, Lúcio; Mário Dinis-Ribeiro; Brandão, Andreia; Lima, Luís. "Enhancing Colorectal Cancer Screening through Machine Learning-Based Biomarker Identification". Paper presented in 2nd Young Research Day, 2024. Lopes, Catarina; Brandão, Andreia; Costa, João; Libânio, Diogo; Mário Dinis-Ribeiro; Pereira, Carina. "Transcriptomic-based molecular signature towards early detection of gastric cancer in intermediate-risk populations". Paper presented in UEG Week 2024, 2024. Lopes, Catarina; Brandão, Andreia; Teixeira, Manuel R.; Mário Dinis-Ribeiro; Pereira, Carina. "Unlocking the screening potential of transcriptomic-based salivary biomarkers in gastric cancer as a proxy of malignant transformation". Paper presented in The FEBS Congress, 2024. Corado, Madalena; Cardoso, Marta; Paulo, Paula; Bernardo Orr; Brandão, Andreia; Henrique, Rui; Teixeira, Manuel R.. "Dissecting the roles of PRUNE2 and PCA3 in the PRUNE2/PCA3/AR triad and prostate cancer progression". Paper presented in IJUP, 2024. Lopes, Catarina; Brandão, Andreia; Teixeira, Manuel R.; Mário Dinis-Ribeiro; Pereira, Carina. "Saliva as a liquid biopsy for gastric cancer screening: A gene expression signature with diagnostic and prognostic potential". Paper presented in 30th Porto Cancer Meeting, 2024. Brandão, Andreia; Almeida, Tatiana; Lopes, Catarina; Teixeira, Manuel R.; Mário Dinis-Ribeiro; Pereira, Carina. "Definition of a novel arachidonic acid pathway-derived risk models for predicting diagnosis and prognosis in gastric cancer: A transcriptomics approach". Paper presented in 30th Porto Cancer Meeting, 2024. Lopes, Catarina; Brandão, Andreia; Costa, João; Libânio, Diogo; Pereira, Carina. "Exploring the transcriptomic landscape towards early detection of cancer in a Western intermediate-risk population". Paper presented in IPO Porto Summit, 2024. Lopes, Catarina; Brandão, Andreia; Costa, João; Libânio, Diogo; Mário Dinis-Ribeiro; Pereira, Carina. "Unveiling the molecular fingerprint of early gastric cancer in a Western population with intermediate risk". Paper presented in 6th ASPIC International Congress, 2024. Cruz, Pedro; Meneses, Olga; Ramos, Raquel; Brandão, Andreia; Veiga, Isabel; Rocha, Patricia; Henrique, Rui; et al. Corresponding author: Paulo, Paula. "Eficácia de anti-EGFR em cancro colorretal metastizado é aumentada pela sobreexpressão de EGFR ou ETV4 e reduzida pela de ETV5 ou ETV1". Paper presented in 3ª Edição do Concurso de Pósteres Científicos Revolution Poster Awards by Pierre Fabre, 2023. Soares, Janine; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Brandão, Andreia; Freitas, Rui; Ferreira, Eduardo; et al. "Glycosylation as a driver of Colorectal cancer aggressiveness". Paper presented in 1st Young Researchers¿s Day, 2023. Ramos, Raquel Almeida; Brandão, Andreia; Cruz, Pedro; Meneses, Olga; Veiga, Isabel; Rocha, Patricia; Henrique, Rui; et al. Corresponding author: Paulo, Paula. "PEA3 transcription factors are prognostic biomarkers of response to anti-EGFR therapy in metastatic colorectal cancer". Paper presented in 1st Young Researcher's Day, 2023. Lopes, Catarina; Brandão, Andreia; Almeida, Tatiana; Teixeira, Manuel R.; Mário Dinis-Ribeiro; Pereira, Carina. "Non- invasive screening of gastric cancer: Can saliva be considered a proxy of gastric tissue?". Paper presented in 1st Young Researchers¿ Day., 2023. Cotton, Sofia; Ferreira, Dylan; Relvas-Santos, Marta; Brandão, Andreia; André Moreira Neto da Silva; Lúcio Lara Santos; Ferreira, José Alexandre. "The Secretin Receptor as a Prognostic Marker Carrying E-Selectin Ligands in Colorectal Cancer". Paper presented in 1ST YOUNG RESEARCHERS´DAY, 2023. Meneses, Olga; Cruz, Pedro; Ramos, Raquel; Brandão, Andreia; Veiga, Isabel; Rocha, Patricia; Henrique, Rui; et al. Corresponding author: Paulo, Paula. "Determinantes moleculares da eficácia terapêutica anti-EGFR no cancro colorretal metastizado.". Paper presented in 20º Congresso Nacional de Oncologia, 2023. Lopes, Catarina; Almeida, Tatiana; Brandão, Andreia; Mário Dinis-Ribeiro; Pereira, Carina. "Can saliva be considered a proxy of gastric tumors? A bioinformatic analysis towards biomarker discovery and early diagnosis". Paper presented in EACR 2023 Innovative Cancer Science, 2023. Almeida, Tatiana; Lopes, Catarina; Brandão, Andreia; Mário Dinis-Ribeiro; Pereira, Carina. "Revisiting the arachidonic acid pathway In gastric cancer: A trancriptomics approach towards novel biomarkers". Paper presented in EACR 2023 Innovative Cancer Science, 2023. https://doi.org/10.1002/1878-0261.13469 Cardoso M., Maia S., Brandão A., Sahasrabudhe R., Lott P., Belter N., Carvajal-Carmona, L.G., Paulo P., Teixeira M.R.. "Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene". Paper presented in 26th Annual Meeting of Portuguese Society of Human Genetics (SPGH), 2022. Silva, M.P., Ferreira, A.L., Brás N.F., Torres L., Brandão A., Pinheiro M., Cardoso M., Vieira J., Palmeira C., Martins. "BUB1B monoallelic germline variants contribute to prostate cancer predisposition by triggering chromosomal instability". Paper presented in 26th Annual Meeting of Portuguese Society of Human Genetics (SPGH), 2022. Silva, Maria P. ((9618-5B5D-E47A); Ferreira, Luisa; Torres, Lurdes; Brandão, Andreia; Pinheiro, Manuela; Palmeira, Carlos; Maiato, Helder; Paulo, Paula; Teixeira, Manuel R.. "A recurrent in-frame BUB1B germline variant in prostate cancer predisposition". Paper presented in EMBO Workshop: Systems Approaches in Cancer, 2021. Brandão, A., Cardoso, M., Silva, M., Peixoto, A., Pinheiro, M., Santos, C., Practical Consortium, Paulo, P., Teixeira, M. "The tale of CHEK2 c.349A>G, a new founder variant associated with prostate cancer risk in populations of European ancestry". Paper presented in 2nd ASEICA EDUCATIONAL SYMPOSIUM, 2019. Almeida M., Brandão A., Vieira D., Cavadas B., Matos E., Rito T., Oppenheimer S., Pereira L., Richards M.B., Soares P.. "Recovering the genetic history of the Pacific using mitochondrial DNA and genome-wide data". Paper presented in XV Encontro Nacional de Biologia Evolutiva, 2019. Ferreira, Joana C; Brandão, Andreia; Cavadas, Bruno; Porto, Graça. "Dating the origins of hemochromatosis with ancient and modern DNA". Paper presented in EMBL Conference: 8th Congress of the International BioIron Society, 2019. Almeida, T.; Brandão, Andreia; Torres, Carmen; Prof. Doutor Luis Cintas; Campanero C; Herranz C; Hernandez P; Igrejas G; Poeta, C Q. D Alexandra Patrícia. "Biotechnology Potential of Enterococcus spp. producers of bacteriocins of fish, mammals and wild birds.". 2019. Foody, M. G. B., Ditchfield, P. W., Ambrose, S. H., Eakin, J. E., Almeida, M., Vieira, D., Brandão, A., Rito, T., Hackla. "Ancient DNA and isotopic analysis of archaeological remains from Guam". Paper presented in 8th International Symposium on Biomolecular Archaeology ISBA, 2018. Brandão, Andreia; Cavadas, Bruno; Porto, Graça; Pereira, Luisa. "The genetic heritage of hemochromatosis: a tale of ancient and modern DNA". Paper presented in 5th I3S Annual Meeting, 2016. Brandão, Andreia; Richards, M., Soares, P., Pereira, L.. "Genetic trace of postglacial and Neolithic movements in Southeast Asia". Paper presented in European Human Genetics Conference, 2015. Brandão, Andreia; Cavadas, B., Pereira, L., Richards, M., Soares, P.. "Complex genetic structure of Southeast Asian populations using genome-wide data.". Paper presented in 19ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2015. Brandão, Andreia; Almeida, T., Muñoz-Atienza, E., Torres, C., Igrejas, G., Hernández, P. E, Herranz, C., Cintas, L., Poeta, P. "Bacteriocinogenic activity of Enterococcus spp. isolated from mullets (Liza ramada) in Portugal". Paper presented in 4th Congress European Microbiologist, 2011. Almeida, T., Brandão, A., Torres, C., Cintas, L., Campanero, C., Herranz, C., Hernandez, P., Igrejas, G., Poeta, P.. "Potencial Biotecnológico de Enterococcus spp. Produtores de Bacteriocinas Isolados de Peixes, Mamíferos e Aves". Paper presented in 3as Jornadas de Biologia, 2009.
Journal article	Cotton, Sofia; Ferreira, Dylan; Relvas-Santos, Marta; Brandão, Andreia; Afonso, Luís Pedro; Miranda, Andreia; Ferreira, Eduardo; et al. "E-selectin affinity glycoproteomics reveals neuroendocrine proteins and the secretin receptor as a poor-prognosis signature in colorectal cancer". Molecular Oncology (2024): https://doi.org/10.1002/1878-0261.13733. 10.1002/1878-0261.13733 Santos, Marlene; Lima, Luis; Carvalho, Serafim; Brandão, Andreia; Barroso, Fátima; Cruz, Agostinho; Medeiros, Rui. "ABCB1 C1236T, G2677TA and C3435T Genetic Polymorphisms and Antidepressant Response Phenotypes: Results from a Portuguese Major Depressive Disorder Cohort". International Journal of Molecular Sciences 25 10 (2024): 5112. http://dx.doi.org/10.3390/ijms25105112. 10.3390/ijms25105112 Paula Paulo; Marta Cardoso; Andreia Brandão; Pedro Pinto; Ariane Falconi; Manuela Pinheiro; Nuno Cerveira; et al. "Genetic landscape of homologous recombination repair genes in early-onset/familial prostate cancer patients". Genes, Chromosomes and Cancer (2023): https://doi.org/10.1002/gcc.23190. Published • 10.1002/gcc.23190 Wang, Anqi; Shen, Jiayi; Rodriguez, Alex A.; Saunders, Edward J.; Chen, Fei; Janivara, Rohini; Darst, Burcu F.; et al. "Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants". Nature Genetics 55 12 (2023): 2065-2074. http://dx.doi.org/10.1038/s41588-023-01534-4. 10.1038/s41588-023-01534-4 Silva, Maria P.; Ferreira, Luisa; Bras, Natercia F.; Torres, Lurdes; Brandão, Andreia; Pinheiro, Manuela; Cardoso, Marta; et al. Corresponding author: Paulo, Paula. "Proceedings of the 26th Annual Meeting of the Portuguese Society of Human Genetics (SPGH Sociedade Portuguesa de Genética Humana) Coimbra, 17-19 November 2022". Medicine 102 13 (2023): e33154. http://dx.doi.org/10.1097/md.0000000000033154. 10.1097/md.0000000000033154 Cardoso, Marta; Maia, Sofia; Brandão, Andreia; Sahasrabudhe, Ruta; Lott, Paul; Belter, Natalia; Carvajal-Carmona, Luis G.; Paulo, Paula; Teixeira, Manuel R.. "Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene". British Journal of Cancer (2022): http://dx.doi.org/10.1038/s41416-022-02125-6. 10.1038/s41416-022-02125-6 Gaiteiro, Cristiana; Soares, Janine; Relvas-Santos, Marta; Peixoto, Andreia; Ferreira, Dylan; Paulo, Paula; Brandão, Andreia; et al. "Glycoproteogenomics characterizes the CD44 splicing code associated with bladder cancer invasion". Theranostics 12 7 (2022): 3150-3177. http://dx.doi.org/10.7150/thno.67409. 10.7150/thno.67409 Barbosa, Ana; Pinto, Pedro; Peixoto, Ana; Guerra, Joana; Pinheiro, Manuela; Santos, Catarina; Pinto, Carla; et al. "Next Generation Sequencing of Tumor and Matched Plasma Samples: Identification of Somatic Variants in ctDNA From Ovarian Cancer Patients". Frontiers in Oncology 11 (2021): http://dx.doi.org/10.3389/fonc.2021.754094. 10.3389/fonc.2021.754094 Conti, David V.; Darst, Burcu F.; Moss, Lilit C.; Saunders, Edward J.; Sheng, Xin; Chou, Alisha; Schumacher, Fredrick R.; et al. "Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction". Nature Genetics 53 1 (2021): 65-75. http://dx.doi.org/10.1038/s41588-020-00748-0. 10.1038/s41588-020-00748-0 Brandão, Andreia; Paulo, Paula; Maia, Sofia; Pinheiro, Manuela; Peixoto, Ana; Cardoso, Marta; Silva, Maria P.; et al. "The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor". Cancers 12 11 (2020): 3254. http://dx.doi.org/10.3390/cancers12113254. 10.3390/cancers12113254 Brandão, Andreia; Paulo, Paula; Teixeira, Manuel R.. "Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications". International Journal of Molecular Sciences 21 14 (2020): 5036. http://dx.doi.org/10.3390/ijms21145036. 10.3390/ijms21145036 Silva, Marina; Oliveira, Marisa; Vieira, Daniel; Brandão, Andreia; Rito, Teresa; Pereira, Joana B.; Fraser, Ross M.; et al. "A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals". BMC Evolutionary Biology 17 1 (2017): http://dx.doi.org/10.1186/s12862-017-0936-9. 10.1186/s12862-017-0936-9 Brandão, Andreia; Eng, Ken Khong; Rito, Teresa; Cavadas, Bruno; Bulbeck, David; Gandini, Francesca; Pala, Maria; et al. "Quantifying the legacy of the Chinese Neolithic on the maternal genetic heritage of Taiwan and Island Southeast Asia". Human Genetics 135 4 (2016): 363-376. http://dx.doi.org/10.1007/s00439-016-1640-3. 10.1007/s00439-016-1640-3 Soares, Pedro A.; Trejaut, Jean A.; Rito, Teresa; Cavadas, Bruno; Hill, Catherine; Eng, Ken Khong; Mormina, Maru; et al. "Resolving the ancestry of Austronesian-speaking populations". Human Genetics 135 3 (2016): 309-326. http://dx.doi.org/10.1007/s00439-015-1620-z. 10.1007/s00439-015-1620-z Cavadas, Bruno; Soares, Pedro; Camacho, Rui; Brandão, Andreia; Costa, Marta D.; Fernandes, Verónica; Pereira, Joana B.; et al. "Fine Time Scaling of Purifying Selection on Human Nonsynonymous mtDNA Mutations Based on the Worldwide Population Tree and Mother-Child Pairs". Human Mutation 36 11 (2015): 1100-1111. http://dx.doi.org/10.1002/humu.22849. 10.1002/humu.22849 ALMEIDA, TEREZA; BRANDÃO, ANDREIA; MUÑOZ-ATIENZA, ESTEFANÍA; GONÇALVES, ALEXANDRE; TORRES, CARMEN; IGREJAS, GILBERTO; HERNÁNDEZ, PABLO E.; et al. "Identification of Bacteriocin Genes in Enterococci Isolated from Game Animals and Saltwater Fish". Journal of Food Protection 74 8 (2011): 1252-1260. http://dx.doi.org/10.4315/0362-028x.jfp-11-016. 10.4315/0362-028x.jfp-11-016 Brandão, A.; Almeida, T.; Muñoz-Atienza, E.; Torres, C.; Igrejas, G.; Hernández, P. E.; Cintas, L. M.; Poeta, P.; Herranz, C.. "Antimicrobial activity and occurrence of bacteriocin structural genes in Enterococcus spp. of human and animal origin isolated in Portugal". Archives of Microbiology 192 11 (2010): 927-936. http://dx.doi.org/10.1007/s00203-010-0619-z. 10.1007/s00203-010-0619-z
Preprint	Peixoto, Andreia; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Freitas, Rui; Veth, Tim S.; Brandão, Andreia; et al. "Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells". 2025. https://www.cell.com/iscience/fulltext/S2589-0042(25)00017-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004225000173%3Fshowall%3Dtrue. 10.1016/j.isci.2025.111758
Thesis / Dissertation	Brandão, Andreia. "Demography of modern humans in Southeast Asia (SEA): a genetic approach". PhD, 2016. Brandão, Andreia. "Identification of bacteriocinogenic enterococci from animal and human origin: antimicrobial activity and genetic and biochemical characterization of their bacteriocins". Master, 2010. Brandão, Andreia. "Prevalence of the C677T polymorphism of Methylenetetrahydrofolate reductase (MTHFR) in chronic hepatitis C". Degree, Universidade de Trás-os-Montes e Alto Douro, 2010.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/11/28	Exploring PRUNE2’s tumor suppressor role in Prostate Cancer	2nd Young Researchers' Day Portuguese Institute of Oncology of Porto (IPO Porto)
2024/05/09	Deciphering PEA3 signaling as a novel mechanism of resistance to anti-EGFR therapy and immunotherapy response in metastatic colorectal cancer	IPO-Porto Summit 2024 Portuguese Institute of Oncology of Porto (IPO Porto) (Porto, Portugal)
2021/09/22	IPO4 as a new DNA repair gene contributing to inherited prostate cancer predisposition	EMBO Workshop on Systems approaches in cancer Mediterranean Institute for Life Sciences (Split, Croatia)
2018/06/14	The genetic impact of the foraging-based Coastal Neolithic and Rice Neolithic in Mainland Southeast Asia	XLII Portuguese Genetics Conference (Portugal)
2017/10/19	The BRCA2 c.156_157insAlu and BRCA1 c.3331_3334del founder mutations	CIMBA - Consortium of Investigators of Modifiers of BRCA1/2 (Spain)
2016/06/03	The settlement and split of the Sundaland Continent	XLII Portuguese Genetics Conference (Portugal)
2015/05/25	Genetic ancestry of Austronesian-speaking populations in Island Southeast Asia and the Pacific	XXXIX Jornadas Portuguesas de Genética (Portugal)
2015/01/26	A decade-long commitment to the OMICS of antimicrobial resistance	1st International Caparica Conference in Antibiotic Resistance - IC2A (Portugal)
2015/01/15	Laos mtDNA study in the MMAP project: preliminary survey findings	The 20th Congress of the Indo-Pacific Prehistory Association (IPPA) (Cambodia)
2015/01/13	Tracing Neolithic migrations in Indo-China and the importance of adding genetic data from regions adjoining the central Mekong route: Laos, Cambodia and inland Vietnam/Thailand	The 20th Congress of the Indo-Pacific Prehistory Association (IPPA) (Cambodia)
2010/11/12	Patrones y procesos de variación (neutral y adaptativa) de la abeja ibérica en el área de hibridación	VI Congreso Apicola Nacional. Nacional (Spain)
2010/09/21	A landscape genetics approach to unravel the complex evolutionary history of the Iberian honey bee hybrid zone.	IUFRO Landscape Ecology Working Group International Conference: Forest Landscapes and Global Change (Portugal)
2009/10/21	Identification of bacteriocinogenic enterococci from human and animal origin.	3as Jornadas de Biologia (Portugal)
2009/10/02	Resistência a antibióticos e factores de virulência em bactérias de animais selvagens e sua função como probióticos.	I Simpósio de Selvagens e Exóticos: A actualidade do sector animal (Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2024/09 - Current	Unveiling Transcriptome Landscape to Enhance Colorectal Cancer Screening: An Integrated Approach Co-supervisor of Mariana Eiras	Doctoral Degree in Biomedical Sciences (PhD) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/09 - Current	GEMS: Genetic markers towards Early gastric cancer individualized Management and Surveillance Co-supervisor of Tatiana Almeida	Doctoral Degree in Biomedical Sciences (PhD) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/09 - Current	Comprehensive characterization of the gastric cancer surfactome by machine learning-assisted glycoproteogenomics towards targetable signatures Co-supervisor of Roberto Pinto	Pathology and Molecular Genetics (PhD) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024/09 - Current	Identificação de potenciais biomarcadores para deteção precoce de cancro colorretal Co-supervisor of Gonçalo Pereira	Master's degree in Biostatistics and Bioinformatics Applied to Health (Master) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2023/09/01 - 2024/12/09	Dissecting the independent roles of PRUNE2 and PCA3 in the function of the PRUNE2/PCA3/AR triad and prostate cancer progression Supervisor of Madalena Ribeiro	Master Degree in Oncology (Master) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/03 - 2024/07	Bioinformatics analysis of molecular alterations in normal tissue adjacent to the tumors in prostate cancer Supervisor of André Vieira	BSc in Artificial Intelligence and Data Science (Degree) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal Faculty of Sciences of the University of Porto, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2019/05/19 - 2019/05/21	The Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome (PRACTICAL) consortium (2019/05/19 - 2019/05/21) Meeting (Member of the Organising Committee)	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2010/09/21 - 2010/09/27	IUFRO Landscape Ecology Working Group International Conference: Forest Landscapes and Global Change (2010/09/21 - 2010/09/27) Congress (Member of the Organising Committee)	Instituto Politécnico de Bragança, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2023/10/13 - 2023/10/15	United European Gastroenterology (UEG) Week 2023 Congress	United European Gastroenterology (UEG) Week 2023 United European Gastroenterology, Austria
2022/11/17 - 2022/11/19	26 Annual meeting of the Portuguese Society of Human Genetics Meeting	26 Annual meeting of the Portuguese Society of Human Genetics Sociedade Portuguesa de Genética Humana, Portugal
2021/09/21 - 2021/09/26	EMBO Workshop on Systems approaches in cancer. Workshop	EMBO Workshop on Systems approaches in cancer Mediterranean Institute for Life Sciences, Croatia
2019/11/28 - 2019/11/29	2nd ASEICA EDUCATIONAL SYMPOSIUM Symposium	2nd ASEICA EDUCATIONAL SYMPOSIUM
2017/10/17 - 2017/10/19	CIMBA - Consortium of Investigators of Modifiers of BRCA1/2 Meeting	CIMBA - Consortium of Investigators of Modifiers of BRCA1/2
2017 - 2017	Specialization courses in Computational Biology (3) - Intro to Python for Data Science (On-line course from DataCamp) Workshop	Intro to Python for Data Science
2015/11/05 - 2015/11/07	19ª Reunião Anual da Sociedade Portuguesa de Genética Humana Congress	19ª Reunião Anual da Sociedade Portuguesa de Genética Humana
2015/06/06 - 2015/06/09	European Human Genetics Conference Conference	European Human Genetics Conference
2015/05/25 - 2015/05/27	XXXIX Jornadas Portuguesas de Genética Congress	XXXIX Jornadas Portuguesas de Genética
2010/09/06 - 2010/09/07	Specialization courses in Computational Biology (4) - Proteomics Workshop Workshop	Proteomics Workshop Universidade de Aveiro, Portugal
2009/10/12 - 2009/10/13	Specialization courses in Computational Biology (5) - The Gulbenkian Training Programme in Bioinformatics 10th Edition: Pathway Analyses Biology Other	The Gulbenkian Training Programme in Bioinformatics 10th Edition: Pathway Analyses Biology Instituto Gulbenkian de Ciência, Portugal

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2023 - Current	Frontiers in Molecular Biosciences (2296-889X)	Frontiers
2022 - Current	Genes (ISSN 2073-4425)	MDPI

Association member

	Society Organization name	Role
2019/09/18 - Current	Portuguese Association for Cancer Research (ASPIC)	ASPIC member: ASPIC429
2019/09/13 - Current	European Association for Cancer Research (EACR)	EACR number: EACR28972

Committee member

	Activity description Role	Institution / Organization
2023/03 - Current	Community of practice on industry-academia collaboration for knowledge valorisation. Co-moderator of topic 7: Digital platforms to better connect industry and academia. Member	European Commission, Belgium

Consulting

	Activity description	Institution / Organization
2019 - Current	Invited to join as an External Expert in the field of Bioinformatics in the project BioS: Digital Skills on Computational Biology for Health Professionals (Ref: 591945-EPP-1-2017-1-DE-EPPKA2-SSA). Link: https://www.bios-project.eu/site/en/project/expert-advisory-board.html

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2024/11 - Current	Advanced R Programming for Multi-omics Data Analysis	Advanced R Programming for Multi-omics Data Analysis (Curso de Especialização Tecnológica)	Escola Portuguesa de Oncologia do Porto (EPOP), Portugal
2024/02 - Current	Bioinformatics and computational biology applied to omics sciences	Master Degree in Oncology (Mestrado)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/10 - Current	Lecture on Clinical Bioinformatics in the Advanced Training Course in Human Laboratory Genetics	Genetics (Curso de Especialização Tecnológica)	Escola Portuguesa de Oncologia do Porto (EPOP), Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2023/03 - Current	Frontiers in Genetics (1664-8021)	Frontiers
2023/02/01 - Current	Genes (2073-4425)	MDPI

Mentoring / Tutoring

	Topic	Student name
2016 - Current	PhD project: Germline mutations in genes involved in the chromosome segregation machinery associated with inherited prostate cancer predisposition	Maria Pedro Silva
2016 - Current	PhD project: Recurrent germline mutations in patients with early-onset and/or familial prostate cancer	Marta Cardoso
2022/09/01 - 2023/12/12	MSc project: PEA3 signalling in the resistance to EGFR therapy in metastatic colorectal cancer: possible biomarkers and therapeutic targets	Raquel Ramos
2019 - 2020	MSc project: Simultaneous detection of germline and somatic mutations in DNA repair genes by next generation sequencing of tumor and blood samples from metastatic prostate cancer patients	Ariene Falconi

Distinctions

Award

2021	Competitive application-Scientific Employment Stimulus (CEEC) - Individual Call 4th Edition (ref: 2021.03835.CEECIND) Fundação para a Ciência e a Tecnologia, Portugal
2011	Competitive application- Four-year Doctoral Fellowship (SFRH/BD/78990/2011) divided between the University of Porto (Portugal) and the University of Huddersfield (United Kingdom). Fundação para a Ciência e a Tecnologia, Portugal
2008	Leonardo da Vinci” (LdV) mobility fellowship. Six-month fellowship to develop my MSc research project at the Universidad Complutense de Madrid, Spain

Other distinction

2020	Selected team for Scicare - Novartis Health Science Accelerator Program Novartis Farma SA, Portugal